{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T22:23:15Z","timestamp":1792102995306,"version":"4.4.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Microbiol"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1007\/s00203-025-04579-7","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T07:20:56Z","timestamp":1764314456000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Investigating in vitro antifungal mechanisms of geraniol against Candida albicans"],"prefix":"10.1007","volume":"208","author":[{"given":"Jiayi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengkun","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,28]]},"reference":[{"key":"4579_CR4","doi-asserted-by":"publisher","first-page":"e00228","DOI":"10.1016\/j.mec.2023.e00228","volume":"17","author":"A Agrawal","year":"2023","unstructured":"Agrawal A, Yang Z, Blenner M (2023) Engineering Yarrowia lipolytica for the biosynthesis of geraniol. Metab Eng Commun 17:e00228","journal-title":"Metab Eng Commun"},{"issue":"2","key":"4579_CR16","first-page":"1","volume":"48","author":"Z Cheng","year":"2022","unstructured":"Cheng Z, Liu G, Nakanishi H (2022) Analysis of the inhibitory effect of 3-phosphoglyceraldehyde on yeast spore germination. Food Ferment Ind 48(2):1\u20136","journal-title":"Food Ferment Ind"},{"issue":"11","key":"4579_CR17","doi-asserted-by":"publisher","first-page":"6061","DOI":"10.3390\/ijms23116061","volume":"23","author":"AA Damus-Grabicka","year":"2022","unstructured":"Damus-Grabicka AA, Da\u015bko M, Hikisz P et al (2022) Biochemical, structural analysis, and docking studies of spiropyrazoline derivatives. Int J Mol Sci 23(11):6061","journal-title":"Int J Mol Sci"},{"issue":"3","key":"4579_CR5","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1080\/10412905.2020.1745697","volume":"32","author":"MHP de Lira","year":"2020","unstructured":"de Lira MHP, de Andrade J\u00fanior FP, Queiroga G et al (2020a) Antimicrobial activity of geraniol: an integrative review. J Essent Oil Res 32(3):187\u2013197","journal-title":"J Essent Oil Res"},{"issue":"3","key":"4579_CR9","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1080\/10412905.2020.1745697","volume":"32","author":"MHP de Lira","year":"2020","unstructured":"de Lira MHP, de Andrade J\u00fanior FP, Moraes GFQ et al (2020b) Antimicrobial activity of geraniol: an integrative review. J Essent Oil Res 32(3):187\u2013197","journal-title":"J Essent Oil Res"},{"issue":"2","key":"4579_CR8","doi-asserted-by":"publisher","first-page":"228","DOI":"10.3109\/13880209.2014.913299","volume":"53","author":"F de Oliveira Pereira","year":"2015","unstructured":"de Oliveira Pereira F, Mendes JM, Lima IO et al (2015) Antifungal activity of geraniol and citronellol, two monoterpene alcohols, against Trichophyton rubrum involves Inhibition of ergosterol biosynthesis. Pharm Biol 53(2):228\u2013234","journal-title":"Pharm Biol"},{"key":"4579_CR13","unstructured":"Gao C (2022) Relationship between abnormal seed development and starch synthesis in cytoplasmic male sterile wheat lines [Master\u2019s thesis]. Northwest A&F University"},{"key":"4579_CR15","unstructured":"Gao W (2023) Mechanisms of acid- and alkali-producing microorganisms on the release of stibnite [Master\u2019s thesis]. China University of Geosciences"},{"issue":"12","key":"4579_CR6","first-page":"1","volume":"13","author":"R Gaonkar","year":"2018","unstructured":"Gaonkar R, Pramod KA, Gurumurthy H (2018) Differential antifungal efficiency of geraniol and citral. Nat Prod Commun 13(12):1\u20134","journal-title":"Nat Prod Commun"},{"issue":"1","key":"4579_CR14","doi-asserted-by":"publisher","first-page":"e54579","DOI":"10.1371\/journal.pone.0054579","volume":"8","author":"SD Huang","year":"2013","unstructured":"Huang SD, Yuan Y, Tang H et al (2013) Tumor cells positive and negative for the common cancer stem cell markers are capable of initiating tumor growth and generating both progenies. PLoS One 8(1):e54579","journal-title":"PLoS One"},{"issue":"6","key":"4579_CR7","doi-asserted-by":"publisher","first-page":"210","DOI":"10.3390\/cosmetics11060210","volume":"11","author":"S Javed","year":"2024","unstructured":"Javed S, Mangla B, Salawi A et al (2024) Essential oils as dermocosmetic agents, their mechanism of action and nanolipidic formulations for maximized skincare. Cosmetics 11(6):210","journal-title":"Cosmetics"},{"issue":"6","key":"4579_CR11","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.3390\/foods12061239","volume":"12","author":"L Kaur","year":"2023","unstructured":"Kaur L, Elamurugan A, Chian FM, Zhu X, Boland M (2023) Protein and lipid digestibility of pasture-raised and grain-finished beef: an in vitro comparison. Foods 12(6):1239","journal-title":"Foods"},{"key":"4579_CR10","first-page":"581","volume":"9","author":"AL Lima","year":"2017","unstructured":"Lima AL, Perez AL, Sousa JP et al (2017) Antifungal activity of geraniol on Candida albicans isolates of pediatric clinic importance. Int J Pharmacol Phytochem Res 9:581\u2013586","journal-title":"Int J Pharmacol Phytochem Res"},{"key":"4579_CR3","unstructured":"Longfei Y (2019) Discovery and mechanism study of active small molecules from traditional Chinese medicine against Candida albicans [Master\u2019s thesis]. Jilin University"},{"key":"4579_CR21","doi-asserted-by":"publisher","first-page":"286","DOI":"10.3389\/fmicb.2012.00286","volume":"3","author":"AC Mesa-Arango","year":"2012","unstructured":"Mesa-Arango AC, Scorzoni L, Zaragoza O (2012) It only takes one to do many jobs: amphotericin B as antifungal and Immunomodulatory drug. Front Microbiol 3:286","journal-title":"Front Microbiol"},{"issue":"4","key":"4579_CR22","doi-asserted-by":"publisher","first-page":"441","DOI":"10.2217\/fmb.11.19","volume":"6","author":"DS Perlin","year":"2011","unstructured":"Perlin DS (2011) Current perspectives on echinocandin class drugs. Future Microbiol 6(4):441\u2013457","journal-title":"Future Microbiol"},{"key":"4579_CR1","doi-asserted-by":"crossref","unstructured":"Schille TB, Sprague JL, Naglik JR, Brunke S, Hube B (2025) Commensalism and pathogenesis of Candida albicans at the mucosal interface. Nat Rev Microbiol 23:1\u201316","DOI":"10.1038\/s41579-025-01174-x"},{"issue":"7","key":"4579_CR2","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1080\/14656566.2021.1873951","volume":"22","author":"L Scorzoni","year":"2021","unstructured":"Scorzoni L, Fuchs BB, Junqueira JC, Mylonakis E (2021) Current and promising pharmacotherapeutic options for candidiasis. Expert Opin Pharmacother 22(7):887\u2013888","journal-title":"Expert Opin Pharmacother"},{"issue":"1","key":"4579_CR20","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1128\/CMR.12.1.40","volume":"12","author":"DJ Sheehan","year":"1999","unstructured":"Sheehan DJ, Hitchcock CA, Sibley CM (1999) Current and emerging azole antifungal agents. Clin Microbiol Rev 12(1):40\u201379","journal-title":"Clin Microbiol Rev"},{"issue":"10","key":"4579_CR12","doi-asserted-by":"publisher","first-page":"2475","DOI":"10.3390\/pharmaceutics15102475","volume":"15","author":"C Silva Pontes","year":"2023","unstructured":"Silva Pontes C, Garcia de Carvalho G, Rosa Perin Leite A, Chorilli M, Spolidorio DMP (2023) Improving drug delivery on Candida albicans using geraniol nanoemulsion. Pharmaceutics 15(10):2475","journal-title":"Pharmaceutics"},{"issue":"2","key":"4579_CR18","first-page":"87","volume":"26","author":"H Wang","year":"1999","unstructured":"Wang H, Zhu X, Wang Y (1999) Fluorescence assay of H\u207a-ATPase proton pump activity in vacuolar membranes. Prog Biochem Biophys 26(2):87\u201390","journal-title":"Prog Biochem Biophys"}],"container-title":["Archives of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00203-025-04579-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00203-025-04579-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00203-025-04579-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T20:05:33Z","timestamp":1771272333000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00203-025-04579-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,28]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["4579"],"URL":"https:\/\/doi.org\/10.1007\/s00203-025-04579-7","relation":{},"ISSN":["0302-8933","1432-072X"],"issn-type":[{"value":"0302-8933","type":"print"},{"value":"1432-072X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,28]]},"assertion":[{"value":"3 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 October 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 November 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 November 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"42"}}