{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T20:21:30Z","timestamp":1782418890109,"version":"3.54.5"},"reference-count":105,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"the Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University","award":["IMSIU-DDRSP2501"],"award-info":[{"award-number":["IMSIU-DDRSP2501"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Microbiol"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1007\/s00203-025-04582-y","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T07:29:36Z","timestamp":1763623776000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Redefining acne treatment: emerging role of probiotics in dermatology"],"prefix":"10.1007","volume":"208","author":[{"given":"Milind","family":"Umekar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anis","family":"Chaudhary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shreya","family":"Koche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damini","family":"Dhule","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supriya","family":"Shidhaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruchi","family":"Khobragade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita","family":"Bonde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan Ahmed","family":"Rudayni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed A. M.","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi","family":"Trivedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,20]]},"reference":[{"key":"4582_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/J.BBRC.2024.149632","volume":"702","author":"A Abdi","year":"2024","unstructured":"Abdi A, Oroojzadeh P, Valivand N, Sambrani R, Lotfi H (2024) Immunological aspects of probiotics for improving skin diseases: influence on the gut-brain-skin axis. Biochem Biophys Res Commun 702:149632. https:\/\/doi.org\/10.1016\/J.BBRC.2024.149632","journal-title":"Biochem Biophys Res Commun"},{"key":"4582_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/J.MICRES.2022.127275","volume":"267","author":"S Aghamohammad","year":"2023","unstructured":"Aghamohammad S, Rohani M (2023) Antibiotic resistance and the alternatives to conventional antibiotics: the role of probiotics and microbiota in combating antimicrobial resistance. Microbiol Res 267:127275. https:\/\/doi.org\/10.1016\/J.MICRES.2022.127275","journal-title":"Microbiol Res"},{"key":"4582_CR3","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1007\/S10522-020-09865-Z\/METRICS","volume":"21","author":"IA Ahmed","year":"2020","unstructured":"Ahmed IA, Mikail MA, Zamakshshari N, Abdullah ASH (2020) Natural anti-aging skincare: role and potential. Biogerontology 21:293\u2013310. https:\/\/doi.org\/10.1007\/S10522-020-09865-Z\/METRICS","journal-title":"Biogerontology"},{"key":"4582_CR4","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/BS.PMBTS.2022.07.003","volume":"191","author":"T Ahrodia","year":"2022","unstructured":"Ahrodia T, Das S, Bakshi S, Das B (2022) Structure, functions, and diversity of the healthy human Microbiome. Prog Mol Biol Transl Sci 191:53\u201382. https:\/\/doi.org\/10.1016\/BS.PMBTS.2022.07.003","journal-title":"Prog Mol Biol Transl Sci"},{"key":"4582_CR5","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1111\/J.1468-2494.2009.00555.X","volume":"32","author":"FH Al-Ghazzewi","year":"2010","unstructured":"Al-Ghazzewi FH, Tester RF (2010) Effect of konjac glucomannan hydrolysates and probiotics on the growth of the skin bacterium Propionibacterium acnes in vitro. Int J Cosmet Sci 32:139\u2013142. https:\/\/doi.org\/10.1111\/J.1468-2494.2009.00555.X","journal-title":"Int J Cosmet Sci"},{"key":"4582_CR6","doi-asserted-by":"publisher","DOI":"10.7759\/CUREUS.51563","author":"A Alyoussef","year":"2024","unstructured":"Alyoussef A (2024) The impact of consuming probiotics and following a vegetarian diet on the outcomes of acne. Cureus. https:\/\/doi.org\/10.7759\/CUREUS.51563","journal-title":"Cureus"},{"key":"4582_CR7","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1007\/S13346-021-00905-W","volume":"11","author":"V Andretto","year":"2021","unstructured":"Andretto V, Rosso A, Brian\u00e7on S, Lollo G (2021) Nanocomposite systems for precise oral delivery of drugs and biologics. Drug Deliv Transl Res 11:445\u2013470. https:\/\/doi.org\/10.1007\/S13346-021-00905-W","journal-title":"Drug Deliv Transl Res"},{"key":"4582_CR8","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.2174\/1389201024666230703115732","volume":"25","author":"R Arora","year":"2023","unstructured":"Arora R, Kaur R, Babbar R, Dhingra S, Dhingra AK, Grewal AS (2023) Evolving advances in the cosmetic use of probiotics and postbiotics: Health, regulatory and marketing aspects. Curr Pharm Biotechnol 25:1349\u20131361. https:\/\/doi.org\/10.2174\/1389201024666230703115732","journal-title":"Curr Pharm Biotechnol"},{"key":"4582_CR9","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/S40257-020-00542-Y","volume":"22","author":"H Baldwin","year":"2021","unstructured":"Baldwin H, Tan J (2021) Effects of diet on acne and its response to treatment. Am J Clin Dermatol 22:55\u201365. https:\/\/doi.org\/10.1007\/S40257-020-00542-Y","journal-title":"Am J Clin Dermatol"},{"key":"4582_CR10","doi-asserted-by":"publisher","first-page":"7535","DOI":"10.2147\/IJN.S337427","volume":"16","author":"KC Baral","year":"2021","unstructured":"Baral KC, Bajracharya R, Lee SH, Han HK (2021) Advancements in the pharmaceutical applications of probiotics: dosage forms and formulation technology. Int J Nanomed 16:7535\u20137556. https:\/\/doi.org\/10.2147\/IJN.S337427","journal-title":"Int J Nanomed"},{"key":"4582_CR11","doi-asserted-by":"publisher","DOI":"10.3389\/FMICB.2020.01662","author":"S Binda","year":"2020","unstructured":"Binda S, Hill C, Johansen E, Obis D, Pot B, Sanders ME, Tremblay A, Ouwehand AC (2020) Criteria to qualify microorganisms as probiotic in foods and dietary supplements. Front Microbiol. https:\/\/doi.org\/10.3389\/FMICB.2020.01662","journal-title":"Front Microbiol"},{"key":"4582_CR12","doi-asserted-by":"publisher","first-page":"249","DOI":"10.2147\/CCID.S135529","volume":"10","author":"S Blanchet-R\u00e9thor\u00e9","year":"2017","unstructured":"Blanchet-R\u00e9thor\u00e9 S, Bourd\u00e8s V, Mercenier A, Haddar CH, Verhoeven PO, Andres P (2017) Effect of a lotion containing the heat-treated probiotic strain Lactobacillus johnsonii NCC 533 on Staphylococcus aureus colonization in atopic dermatitis. Clin Cosmet Investig Dermatol 10:249\u2013257. https:\/\/doi.org\/10.2147\/CCID.S135529","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"4582_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/J.EJPHAR.2022.174936","volume":"923","author":"SG Bungau","year":"2022","unstructured":"Bungau SG, Tit DM, Vesa CM, Abid A, Szilagyi DV, Radu AF, Bungau AF, Tarce AG, Behl T, Stoicescu M, Brisc CM, Gitea D, Nechifor AC, Endres L (2022) Non-conventional therapeutical approaches to acne vulgaris related to its association with metabolic disorders. Eur J Pharmacol 923:174936. https:\/\/doi.org\/10.1016\/J.EJPHAR.2022.174936","journal-title":"Eur J Pharmacol"},{"issue":"8","key":"4582_CR14","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.3390\/MICROORGANISMS8071026","volume":"8","author":"\u00c9 Butler","year":"2020","unstructured":"Butler \u00c9, Lundqvist C, Axelsson J (2020) Lactobacillus reuteri DSM 17938 as a novel topical cosmetic ingredient: a proof of concept clinical study in adults with atopic dermatitis. Microorganisms 8(8):1026. https:\/\/doi.org\/10.3390\/MICROORGANISMS8071026","journal-title":"Microorganisms"},{"key":"4582_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/J.ANAEROBE.2020.102243","volume":"64","author":"HM Cha","year":"2020","unstructured":"Cha HM, Kim SK, Kook MC, Yi TH (2020) Lactobacillus paraplantarum THG-G10 as a potential anti-acne agent with anti-bacterial and anti-inflammatory activities. Anaerobe 64:102243. https:\/\/doi.org\/10.1016\/J.ANAEROBE.2020.102243","journal-title":"Anaerobe"},{"key":"4582_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-823733-5.00013-1","author":"A Chaudhari","year":"2022","unstructured":"Chaudhari A, Dwivedi MK (2022) The concept of probiotics, prebiotics, postbiotics, synbiotics, nutribiotics, and pharmabiotics. Probiotics Prev Manage Hum Dis: Sci Perspect. https:\/\/doi.org\/10.1016\/B978-0-12-823733-5.00013-1","journal-title":"Probiotics Prev Manage Hum Dis: Sci Perspect"},{"key":"4582_CR17","doi-asserted-by":"publisher","DOI":"10.1111\/EXD.15150","volume":"33","author":"CT Cheung","year":"2024","unstructured":"Cheung CT, Lancien U, Corvec S, Mengeaud V, Mias C, V\u00e9ziers J, Khammari A, Dr\u00e9no B (2024) Pro-inflammatory activity of Cutibacterium acnes phylotype IA1 and extracellular vesicles: an in vitro study. Exp Dermatol 33:e15150. https:\/\/doi.org\/10.1111\/EXD.15150","journal-title":"Exp Dermatol"},{"issue":"16","key":"4582_CR18","doi-asserted-by":"publisher","DOI":"10.3390\/NU16040539","volume":"16","author":"S Ci\u0119\u017cki","year":"2024","unstructured":"Ci\u0119\u017cki S, Odyjewska E, Bossowski A, G\u0142owi\u0144ska-Olszewska B (2024) Not only metabolic complications of childhood obesity. Nutrients 16(16):539. https:\/\/doi.org\/10.3390\/NU16040539","journal-title":"Nutrients"},{"key":"4582_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/J.FOODRES.2020.109502","volume":"136","author":"PF Cuevas-Gonz\u00e1lez","year":"2020","unstructured":"Cuevas-Gonz\u00e1lez PF, Liceaga AM, Aguilar-Toal\u00e1 JE (2020) Postbiotics and paraprobiotics: from concepts to applications. Food Res Int 136:109502. https:\/\/doi.org\/10.1016\/J.FOODRES.2020.109502","journal-title":"Food Res Int"},{"key":"4582_CR20","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.ijd_655_22","volume":"67","author":"H Cui","year":"2022","unstructured":"Cui H, Feng C, Guo C, Duan Z (2022) Development of novel topical anti-acne cream containing postbiotics for mild-to-moderate acne: an observational study to evaluate its efficacy. Indian J Dermatol 67:667. https:\/\/doi.org\/10.4103\/ijd.ijd_655_22","journal-title":"Indian J Dermatol"},{"issue":"3","key":"4582_CR21","doi-asserted-by":"publisher","DOI":"10.3390\/COSMETICS10030077","volume":"10","author":"I Dapkevicius","year":"2023","unstructured":"Dapkevicius I, Romualdo V, Marques AC, Lopes CM, Amaral MH (2023) Acne vulgaris topical therapies: application of probiotics as a new prevention strategy. Cosmet 10(3):77. https:\/\/doi.org\/10.3390\/COSMETICS10030077","journal-title":"Cosmet"},{"key":"4582_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/J.AFRES.2022.100185","volume":"2","author":"TK Das","year":"2022","unstructured":"Das TK, Pradhan S, Chakrabarti S, Mondal KC, Ghosh K (2022) Current status of probiotic and related health benefits. Appl Food Res 2:100185. https:\/\/doi.org\/10.1016\/J.AFRES.2022.100185","journal-title":"Appl Food Res"},{"key":"4582_CR23","volume":"16","author":"KE Dolan","year":"2017","unstructured":"Dolan KE, Pizano JM, Gossard CM, Williamson CB, Burns CM, Gasta MG, Finley HJ, Parker EC, Lipski EA (2017) Probiotics and disease: a comprehensive summary\u2014part 6, skin health. Integr Med: Clin J 16:32","journal-title":"Integr Med: Clin J"},{"key":"4582_CR24","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-15-4759-1_3","author":"MM El-Dalatony","year":"2020","unstructured":"El-Dalatony MM, Li X (2020) Introduction to probiotics and their potential health benefits. Gut Remediat Environ Pollut: Potential Roles Probiotics Gut Microb. https:\/\/doi.org\/10.1007\/978-981-15-4759-1_3","journal-title":"Gut Remediat Environ Pollut: Potential Roles Probiotics Gut Microb"},{"key":"4582_CR25","doi-asserted-by":"publisher","first-page":"1486","DOI":"10.3390\/MICROORGANISMS9071486\/S1","volume":"9","author":"M Espinoza-Monje","year":"2021","unstructured":"Espinoza-Monje M, Campos J, Alvarez Villamil E, Jerez A, Dentice Maidana S, Elean M, Salva S, Kitazawa H, Villena J, Garc\u00eda-Cancino A (2021) Characterization of Weissella viridescens uco-smc3 as a potential probiotic for the skin: its beneficial role in the pathogenesis of acne vulgaris. Microorganisms 9:1486. https:\/\/doi.org\/10.3390\/MICROORGANISMS9071486\/S1","journal-title":"Microorganisms"},{"key":"4582_CR26","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1146\/ANNUREV-FOOD-072023-034528\/CITE\/REFWORKS","volume":"15","author":"E Esposito","year":"2024","unstructured":"Esposito E, Pecorelli A, Ferrara F, AnnLila M, Valacchi G (2024) Feeding the body through the skin: ethosomes and transethosomes as a new topical delivery system for bioactive compounds. Annu Rev Food Sci Technol 15:53\u201378. https:\/\/doi.org\/10.1146\/ANNUREV-FOOD-072023-034528\/CITE\/REFWORKS","journal-title":"Annu Rev Food Sci Technol"},{"key":"4582_CR27","doi-asserted-by":"publisher","first-page":"110496","DOI":"10.1016\/J.LWT.2020.110496","volume":"137","author":"ML Estilarte","year":"2021","unstructured":"Estilarte ML, Tymczyszyn EE, Serradell M, de los \u00c1, Carasi P (2021) Freeze-drying of Enterococcus durans: effect on their probiotics and biopreservative properties. LWT 137:110496. https:\/\/doi.org\/10.1016\/J.LWT.2020.110496","journal-title":"LWT"},{"key":"4582_CR28","doi-asserted-by":"publisher","first-page":"720393","DOI":"10.3389\/FIMMU.2021.720393\/BIBTEX","volume":"12","author":"Z Fang","year":"2021","unstructured":"Fang Z, Li L, Zhang H, Zhao J, Lu W, Chen W (2021) Gut Microbiota, Probiotics, and their interactions in prevention and treatment of atopic dermatitis: A review. Front Immunol 12:720393. https:\/\/doi.org\/10.3389\/FIMMU.2021.720393\/BIBTEX","journal-title":"Front Immunol"},{"issue":"7","key":"4582_CR29","doi-asserted-by":"publisher","DOI":"10.3390\/MICROORGANISMS7030083","volume":"7","author":"K Fenster","year":"2019","unstructured":"Fenster K, Freeburg B, Hollard C, Wong C, Laursen RR, Ouwehand AC (2019) The production and delivery of probiotics: a review of a practical approach. Microorganisms 7(7):83. https:\/\/doi.org\/10.3390\/MICROORGANISMS7030083","journal-title":"Microorganisms"},{"key":"4582_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-822909-5.00001-0","author":"S Fijan","year":"2021","unstructured":"Fijan S, ter Haar JA, Varga L (2021) Probiotic microorganisms and their benefit to human health. Adv Probiotics. https:\/\/doi.org\/10.1016\/B978-0-12-822909-5.00001-0","journal-title":"Adv Probiotics"},{"key":"4582_CR31","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/S13555-020-00476-7","volume":"11","author":"K Fran\u00e7a","year":"2021","unstructured":"Fran\u00e7a K (2021) Topical probiotics in dermatological therapy and skincare: a concise review. Dermatol Ther (Heidelb) 11:71\u201377. https:\/\/doi.org\/10.1007\/S13555-020-00476-7","journal-title":"Dermatol Ther (Heidelb)"},{"key":"4582_CR32","doi-asserted-by":"publisher","DOI":"10.3390\/fermentation8030117","volume":"8","author":"AJ Garcia-Brand","year":"2022","unstructured":"Garcia-Brand AJ, Quezada V, Gonzalez-Melo C, Bola\u00f1os-Barbosa AD, Cruz JC, Reyes LH (2022) Novel developments on stimuli-responsive probiotic encapsulates: from smart hydrogels to nanostructured platforms. Fermentation 8:117. https:\/\/doi.org\/10.3390\/fermentation8030117","journal-title":"Fermentation"},{"key":"4582_CR33","doi-asserted-by":"publisher","first-page":"107","DOI":"10.30476\/TIPS.2022.95146.1142","volume":"8","author":"P Ghasemiyeh","year":"2022","unstructured":"Ghasemiyeh P, Noorizadeh K, Dehghan D, Rasekh S, Zadmehr O, Mohammadi-Samani S (2022) The role of different factors in pathophysiology of acne and potential therapeutic options: a brief review. Trends Pharm Sci 8:107\u2013118. https:\/\/doi.org\/10.30476\/TIPS.2022.95146.1142","journal-title":"Trends Pharm Sci"},{"key":"4582_CR34","doi-asserted-by":"publisher","DOI":"10.3390\/POLYM13162729","volume":"13","author":"R Gheorghita","year":"2021","unstructured":"Gheorghita R, Anchidin-Norocel L, Filip R, Dimian M, Covasa M (2021) Applications of biopolymers for drugs and probiotics delivery. Polymers 13:2729. https:\/\/doi.org\/10.3390\/POLYM13162729","journal-title":"Polymers"},{"key":"4582_CR35","doi-asserted-by":"publisher","DOI":"10.1111\/DTH.13279","volume":"33","author":"A Goodarzi","year":"2020","unstructured":"Goodarzi A, Mozafarpoor S, Bodaghabadi M, Mohamadi M (2020) The potential of probiotics for treating acne vulgaris: a review of literature on acne and microbiota. Dermatol Ther 33:e13279. https:\/\/doi.org\/10.1111\/DTH.13279","journal-title":"Dermatol Ther"},{"key":"4582_CR36","doi-asserted-by":"publisher","DOI":"10.3389\/FMICB.2022.929346","volume":"13","author":"HZ Gou","year":"2022","unstructured":"Gou HZ, Zhang YL, Ren LF, Li ZJ, Zhang L (2022) How do intestinal probiotics restore the intestinal barrier? Front Microbiol 13:929346. https:\/\/doi.org\/10.3389\/FMICB.2022.929346","journal-title":"Front Microbiol"},{"issue":"2","key":"4582_CR37","doi-asserted-by":"publisher","DOI":"10.3390\/PATHOGENS11020121","volume":"11","author":"A Gueniche","year":"2022","unstructured":"Gueniche A, Perin O, Bouslimani A, Landemaine L, Misra N, Cupferman S, Aguilar L, Clavaud C, Chopra T, Khodr A (2022) Advances in microbiome-derived solutions and methodologies are founding a new era in skin health and care. Pathogens 11(2):121. https:\/\/doi.org\/10.3390\/PATHOGENS11020121","journal-title":"Pathogens"},{"key":"4582_CR38","doi-asserted-by":"publisher","DOI":"10.1208\/S12249-021-02024-8","author":"S Gurram","year":"2021","unstructured":"Gurram S, Jha DK, Shah DS, Kshirsagar MM, Amin PD (2021) Insights on the critical parameters affecting the probiotic viability during stabilization process and formulation development. AAPS PharmSciTech. https:\/\/doi.org\/10.1208\/S12249-021-02024-8","journal-title":"AAPS PharmSciTech"},{"key":"4582_CR39","doi-asserted-by":"publisher","first-page":"557","DOI":"10.3390\/PHARMACEUTICS14030557","volume":"14","author":"M Habeebuddin","year":"2022","unstructured":"Habeebuddin M, Karnati RK, Shiroorkar PN, Nagaraja S, Asdaq SMB, Anwer MK, Fattepur S (2022) Topical probiotics: more than a skin deep. Pharmaceutics 14:557. https:\/\/doi.org\/10.3390\/PHARMACEUTICS14030557","journal-title":"Pharmaceutics"},{"key":"4582_CR40","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-99-1463-0_21","author":"HA Hallowell","year":"2023","unstructured":"Hallowell HA, Gao AL, Kelly KE, Suez J (2023) Interactions between microbial therapeutics and the endogenous microbiome. Probiotics Prebiotics Synbiotics Postbiotics: Hum Microbiome Hum Health. https:\/\/doi.org\/10.1007\/978-981-99-1463-0_21","journal-title":"Probiotics Prebiotics Synbiotics Postbiotics: Hum Microbiome Hum Health"},{"key":"4582_CR41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/S13048-020-00670-3\/FIGURES\/2","volume":"13","author":"FF He","year":"2020","unstructured":"He FF, Li YM (2020) Role of gut microbiota in the development of insulin resistance and the mechanism underlying polycystic ovary syndrome: A review. J Ovarian Res 13:1\u201313. https:\/\/doi.org\/10.1186\/S13048-020-00670-3\/FIGURES\/2","journal-title":"J Ovarian Res"},{"key":"4582_CR42","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/J.FBP.2021.04.016","volume":"128","author":"E Hirsch","year":"2021","unstructured":"Hirsch E, Pantea E, Vass P, Domj\u00e1n J, Moln\u00e1r M, Suhajda \u00c1, Andersen SK, Vigh T, Verreck G, Marosi GJ, Nagy ZK (2021) Probiotic bacteria stabilized in orally dissolving nanofibers prepared by high-speed electrospinning. Food Bioprod Process 128:84\u201394. https:\/\/doi.org\/10.1016\/J.FBP.2021.04.016","journal-title":"Food Bioprod Process"},{"issue":"10","key":"4582_CR43","doi-asserted-by":"publisher","first-page":"2699","DOI":"10.1039\/d0na00952k","volume":"3","author":"SM Hoorfar","year":"2021","unstructured":"Hoorfar SM, Razavi S, Janfaza S, Tasnim N, Gibson DL, Hoorfar M, Janfaza S, Tasnim N, Gibson DL (2021) Nanomaterial-based encapsulation for controlled gastrointestinal delivery of viable probiotic bacteria. Nanoscale Adv 3(10):2699\u20132709. https:\/\/doi.org\/10.1039\/d0na00952k","journal-title":"Nanoscale Adv"},{"key":"4582_CR44","doi-asserted-by":"publisher","DOI":"10.7243\/2052-6180-3-5","author":"M-CJ Huang","year":"2018","unstructured":"Huang M-CJ, Tang J (2018) Formulating topical products containing live microorganisms as the active ingredient. Microbiol Discov. https:\/\/doi.org\/10.7243\/2052-6180-3-5","journal-title":"Microbiol Discov"},{"key":"4582_CR45","doi-asserted-by":"publisher","DOI":"10.3389\/FMICB.2022.942027","volume":"13","author":"Y Huang","year":"2022","unstructured":"Huang Y, Liu L, Hao Z, Chen L, Yang Q, Xiong X, Deng Y (2022) Potential roles of gut microbial tryptophan metabolites in the complex pathogenesis of acne vulgaris. Front Microbiol 13:942027. https:\/\/doi.org\/10.3389\/FMICB.2022.942027","journal-title":"Front Microbiol"},{"key":"4582_CR46","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/978-981-16-5628-6_4","volume":"3","author":"L Huuskonen","year":"2021","unstructured":"Huuskonen L, Anglenius H, Tiihonen K, Ouwehand AC (2021) Probiotics and their various forms supporting skin health. Probiotic Res Therapeutics: 3: Probiotics Gut Skin Axis\u2013Inside Out Outside in 3:57\u2013109. https:\/\/doi.org\/10.1007\/978-981-16-5628-6_4","journal-title":"Probiotic Res Therapeutics: 3: Probiotics Gut Skin Axis\u2013Inside Out Outside in"},{"key":"4582_CR47","doi-asserted-by":"publisher","first-page":"1774","DOI":"10.1080\/07373937.2021.1874968","volume":"40","author":"R Jawan","year":"2022","unstructured":"Jawan R, Abbasiliasi S, Tan JS, Kapri MR, Mustafa S, Halim M, Ariff AB (2022) Influence of type and concentration of lyoprotectants, storage temperature and storage duration on cell viability and antibacterial activity of freeze-dried lactic acid bacterium, Lactococcus lactis Gh1. Drying Technol 40:1774\u20131790. https:\/\/doi.org\/10.1080\/07373937.2021.1874968","journal-title":"Drying Technol"},{"issue":"22","key":"4582_CR48","doi-asserted-by":"publisher","DOI":"10.3390\/IJMS22137055","volume":"22","author":"R Kashapov","year":"2021","unstructured":"Kashapov R, Ibragimova A, Pavlov R, Gabdrakhmanov D, Kashapova N, Burilova E, Zakharova L, Sinyashin O (2021) Nanocarriers for biomedicine: from lipid formulations to inorganic and hybrid nanoparticles. Int J Mol Sci 22(22):7055. https:\/\/doi.org\/10.3390\/IJMS22137055","journal-title":"Int J Mol Sci"},{"key":"4582_CR49","doi-asserted-by":"publisher","first-page":"1851","DOI":"10.2174\/1389201023666220411090301","volume":"23","author":"S Kianmehr","year":"2022","unstructured":"Kianmehr S, Jahani M, Moazzen N, Ahanchian H, Khameneh B (2022) The potential of probiotics for treating skin disorders: a concise review. Curr Pharm Biotechnol 23:1851\u20131863. https:\/\/doi.org\/10.2174\/1389201023666220411090301","journal-title":"Curr Pharm Biotechnol"},{"key":"4582_CR50","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.3390\/NU13041368\/S1","volume":"13","author":"MJ Kim","year":"2021","unstructured":"Kim MJ, Kim KP, Choi E, Yim JH, Choi C, Yun HS, Ahn HY, Oh JY, Cho Y (2021) Effects of Lactobacillus plantarum cjlp55 on clinical improvement, skin condition and urine bacterial extracellular vesicles in patients with acne vulgaris: A randomized, double-blind, placebo-controlled study. Nutrients 13:1368. https:\/\/doi.org\/10.3390\/NU13041368\/S1","journal-title":"Nutrients"},{"key":"4582_CR51","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1146\/ANNUREV.MICRO.091208.073341","volume":"63","author":"M Kleerebezem","year":"2009","unstructured":"Kleerebezem M, Vaughan EE (2009) Probiotic and gut lactobacilli and bifidobacteria: molecular approaches to study diversity and activity. Annu Rev Microbiol 63:269\u2013290. https:\/\/doi.org\/10.1146\/ANNUREV.MICRO.091208.073341","journal-title":"Annu Rev Microbiol"},{"key":"4582_CR52","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1111\/EXD.14032","volume":"29","author":"R Knackstedt","year":"2020","unstructured":"Knackstedt R, Knackstedt T, Gatherwright J (2020) The role of topical probiotics in skin conditions: a systematic review of animal and human studies and implications for future therapies. Exp Dermatol 29:15\u201321. https:\/\/doi.org\/10.1111\/EXD.14032","journal-title":"Exp Dermatol"},{"key":"4582_CR53","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1111\/BJD.19477","volume":"184","author":"AM Layton","year":"2021","unstructured":"Layton AM, Thiboutot D, Tan J (2021) Reviewing the global burden of acne: how could we improve care to reduce the burden? Br J Dermatol 184:219\u2013225. https:\/\/doi.org\/10.1111\/BJD.19477","journal-title":"Br J Dermatol"},{"key":"4582_CR54","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2022.100521","author":"S Lebeer","year":"2022","unstructured":"Lebeer S, Oerlemans EFM, Claes I, Henkens T, Delanghe L, Wuyts S, Spacova I, van den Broek MFL, Tuyaerts I, Wittouck S, De Boeck I, Allonsius CN, Kiekens F, Lambert J (2022) Selective targeting of skin pathobionts and inflammation with topically applied lactobacilli. Cell Rep Med. https:\/\/doi.org\/10.1016\/j.xcrm.2022.100521","journal-title":"Cell Rep Med"},{"key":"4582_CR55","doi-asserted-by":"publisher","DOI":"10.7573\/DIC.2021-8-6","author":"AKC Leung","year":"2021","unstructured":"Leung AKC, Barankin B, Lam JM, Leong KF, Hon KL (2021) Dermatology: how to manage acne vulgaris. Drugs Context. https:\/\/doi.org\/10.7573\/DIC.2021-8-6","journal-title":"Drugs Context"},{"key":"4582_CR56","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1111\/JAM.13349","volume":"122","author":"EG Lopes","year":"2017","unstructured":"Lopes EG, Moreira DA, Gull\u00f3n P, Gull\u00f3n B, Cardelle-Cobas A, Tavaria FK (2017) Topical application of probiotics in skin: adhesion, antimicrobial and antibiofilm in vitro assays. J Appl Microbiol 122:450\u2013461. https:\/\/doi.org\/10.1111\/JAM.13349","journal-title":"J Appl Microbiol"},{"key":"4582_CR57","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1111\/WRR.12607","volume":"25","author":"J Lukic","year":"2017","unstructured":"Lukic J, Chen V, Strahinic I, Begovic J, Lev-Tov H, Davis SC, Tomic-Canic M, Pastar I (2017) Probiotics or pro-healers: the role of beneficial bacteria in tissue repair. Wound Repair Regen 25:912\u2013922. https:\/\/doi.org\/10.1111\/WRR.12607","journal-title":"Wound Repair Regen"},{"key":"4582_CR58","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/J.JCONREL.2022.10.030","volume":"352","author":"Y Luo","year":"2022","unstructured":"Luo Y, De Souza C, Ramachandran M, Wang S, Yi H, Ma Z, Zhang L, Lin K (2022) Precise oral delivery systems for probiotics: a review. J Controlled Release 352:371\u2013384. https:\/\/doi.org\/10.1016\/J.JCONREL.2022.10.030","journal-title":"J Controlled Release"},{"key":"4582_CR59","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2022.2096995","author":"MR Mahmud","year":"2022","unstructured":"Mahmud MR, Akter S, Tamanna SK, Mazumder L, Esti IZ, Banerjee S, Akter S, Hasan MR, Acharjee M, Hossain MS, Pirttil\u00e4 AM (2022) Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases. Gut Microbes. https:\/\/doi.org\/10.1080\/19490976.2022.2096995","journal-title":"Gut Microbes"},{"key":"4582_CR60","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.det.2018.07.002","volume":"37","author":"JW Marson","year":"2019","unstructured":"Marson JW, Baldwin HE (2019) New concepts, concerns, and creations in acne. Dermatol Clin 37:1\u20139. https:\/\/doi.org\/10.1016\/j.det.2018.07.002","journal-title":"Dermatol Clin"},{"issue":"9","key":"4582_CR61","doi-asserted-by":"publisher","first-page":"Page303","DOI":"10.3390\/MICROORGANISMS9020303","volume":"2021","author":"C Mayslich","year":"2021","unstructured":"Mayslich C, Grange PA, Dupin N (2021) Cutibacterium acnes as an opportunistic pathogen: an update of its Virulence-Associated factors. Microorganisms 2021(9):Page303\u20139303. https:\/\/doi.org\/10.3390\/MICROORGANISMS9020303","journal-title":"Microorganisms"},{"key":"4582_CR62","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1007\/S12602-021-09824-1","volume":"14","author":"IJ McLoughlin","year":"2022","unstructured":"McLoughlin IJ, Wright EM, Tagg JR, Jain R, Hale JDF (2022) Skin microbiome\u2014the next frontier for probiotic intervention. Probiotics Antimicrob Proteins 14:630\u2013647. https:\/\/doi.org\/10.1007\/S12602-021-09824-1","journal-title":"Probiotics Antimicrob Proteins"},{"key":"4582_CR63","doi-asserted-by":"publisher","DOI":"10.1016\/J.MICRES.2024.127749","volume":"285","author":"TT Min","year":"2024","unstructured":"Min TT, Choowongkomon K, Htoo HH, Nonejuie P, Haltrich D, Yamabhai M (2024) Anti-CAMP1 IgG promotes macrophage phagocytosis of Cutibacterium acnes type II. Microbiol Res 285:127749. https:\/\/doi.org\/10.1016\/J.MICRES.2024.127749","journal-title":"Microbiol Res"},{"key":"4582_CR64","doi-asserted-by":"publisher","DOI":"10.1016\/J.MICRES.2023.127595","volume":"281","author":"S Mohammad","year":"2024","unstructured":"Mohammad S, Karim MR, Iqbal S, Lee JH, Mathiyalagan R, Kim YJ, Yang DU, Yang DC (2024) Atopic dermatitis: pathophysiology, microbiota, and metabolome \u2013 a comprehensive review. Microbiol Res 281:127595. https:\/\/doi.org\/10.1016\/J.MICRES.2023.127595","journal-title":"Microbiol Res"},{"key":"4582_CR65","doi-asserted-by":"publisher","DOI":"10.3390\/MICROORGANISMS10071344","author":"G Mosaico","year":"2022","unstructured":"Mosaico G, Artuso G, Pinna M, Denotti G, Orr\u00f9 G, Casu C (2022) Host microbiota balance in teenagers with gum hypertrophy concomitant with acne vulgaris: role of oral hygiene associated with topical probiotics. Microorganisms. https:\/\/doi.org\/10.3390\/MICROORGANISMS10071344","journal-title":"Microorganisms"},{"key":"4582_CR66","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.1111\/IJD.13972","volume":"57","author":"VHM Mottin","year":"2018","unstructured":"Mottin VHM, Suyenaga ES (2018) An approach on the potential use of probiotics in the treatment of skin conditions: acne and atopic dermatitis. Int J Dermatol 57:1425\u20131432. https:\/\/doi.org\/10.1111\/IJD.13972","journal-title":"Int J Dermatol"},{"key":"4582_CR67","doi-asserted-by":"publisher","DOI":"10.1126\/SCITRANSLMED.AAH4680","author":"T Nakatsuji","year":"2017","unstructured":"Nakatsuji T, Chen TH, Narala S, Chun KA, Two AM, Yun T, Shafiq F, Kotol PF, Bouslimani A, Melnik AV, Latif H, Kim JN, Lockhart A, Artis K, David G, Taylor P, Streib J, Dorrestein PC, Grier A, Gill SR, Zengler K, Hata TR, Leung DYM, Gallo RL (2017) Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis. Sci Transl Med. https:\/\/doi.org\/10.1126\/SCITRANSLMED.AAH4680","journal-title":"Sci Transl Med"},{"key":"4582_CR68","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1007\/S40257-017-0300-2","volume":"18","author":"M Notay","year":"2017","unstructured":"Notay M, Foolad N, Vaughn AR, Sivamani RK (2017) Probiotics, prebiotics, and synbiotics for the treatment and prevention of adult dermatological diseases. Am J Clin Dermatol 18:721\u2013732. https:\/\/doi.org\/10.1007\/S40257-017-0300-2","journal-title":"Am J Clin Dermatol"},{"issue":"9","key":"4582_CR69","doi-asserted-by":"publisher","first-page":"168","DOI":"10.3390\/JCM9010168","volume":"9","author":"SY Park","year":"2020","unstructured":"Park SY, Kim HS, Lee SH, Kim S (2020) Characterization and analysis of the skin microbiota in acne: impact of systemic antibiotics. J Clin Med 2020 9(9):168. https:\/\/doi.org\/10.3390\/JCM9010168","journal-title":"J Clin Med 2020"},{"key":"4582_CR70","doi-asserted-by":"publisher","first-page":"417","DOI":"10.3390\/MICROORGANISMS11020417\/S1","volume":"11","author":"C Podrini","year":"2023","unstructured":"Podrini C, Schramm L, Marianantoni G, Apolinarska J, McGuckin C, Forraz N, Milet C, Desroches AL, Payen P, D\u2019Aguanno M, Biazzo M (2023) Topical administration of Lactiplantibacillus plantarum (SkinDuoTM) serum improves Anti-Acne properties. Microorganisms 11:417. https:\/\/doi.org\/10.3390\/MICROORGANISMS11020417\/S1","journal-title":"Microorganisms"},{"key":"4582_CR71","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/J.ADDR.2011.01.012","volume":"63","author":"TW Prow","year":"2011","unstructured":"Prow TW, Grice JE, Lin LL, Faye R, Butler M, Becker W, Wurm EMT, Yoong C, Robertson TA, Soyer HP, Roberts MS (2011) Nanoparticles and microparticles for skin drug delivery. Adv Drug Deliv Rev 63:470\u2013491. https:\/\/doi.org\/10.1016\/J.ADDR.2011.01.012","journal-title":"Adv Drug Deliv Rev"},{"key":"4582_CR72","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.3390\/molecules26051249","volume":"26","author":"S Puebla-Barragan","year":"2021","unstructured":"Puebla-Barragan S, Reid G (2021) Probiotics in cosmetic and personal care products: trends and challenges. Molecules 26:1249","journal-title":"Molecules"},{"key":"4582_CR73","doi-asserted-by":"publisher","first-page":"3966","DOI":"10.1039\/D3FO00152K","volume":"14","author":"S Rawal","year":"2023","unstructured":"Rawal S, Ali SA (2023) Probiotics and postbiotics play a role in maintaining dermal health. Food Funct 14:3966\u20133981. https:\/\/doi.org\/10.1039\/D3FO00152K","journal-title":"Food Funct"},{"key":"4582_CR74","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/J.TIFS.2021.05.022","volume":"114","author":"PM Reque","year":"2021","unstructured":"Reque PM, Brandelli A (2021) Encapsulation of probiotics and nutraceuticals: applications in functional food industry. Trends Food Sci Technol 114:1\u201310. https:\/\/doi.org\/10.1016\/J.TIFS.2021.05.022","journal-title":"Trends Food Sci Technol"},{"key":"4582_CR75","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1007\/S13555-021-00664-Z","volume":"12","author":"F Rinaldi","year":"2022","unstructured":"Rinaldi F, Marotta L, Mascolo A, Amoruso A, Pane M, Giuliani G, Pinto D (2022) Facial acne: a randomized, double-blind, placebo-controlled study on the clinical efficacy of a symbiotic dietary supplement. Dermatol Ther 12:577\u2013589. https:\/\/doi.org\/10.1007\/S13555-021-00664-Z","journal-title":"Dermatol Ther"},{"key":"4582_CR1000","doi-asserted-by":"crossref","unstructured":"Rocha M, Barnes F, Calder\u00f3\u00f3n J, Fierro-Arias L, Gomez CEM, Munoz C, Jannell O, Troieli P (2024) Acne treatment challenges-Recommendations of Latin American expert consensus. Anais Bras de Dermatol 99(3):414\u2013424","DOI":"10.1016\/j.abd.2023.09.001"},{"key":"4582_CR76","doi-asserted-by":"publisher","DOI":"10.1111\/DTH.13439","volume":"33","author":"E Rodighiero","year":"2020","unstructured":"Rodighiero E, Bertolani M, Saleri R, Pedrazzi G, Lotti T, Feliciani C, Satolli F (2020) Do acne treatments affect insulin-like growth factor-1 serum levels? A clinical and laboratory study on patients with acne vulgaris. Dermatol Ther 33:e13439. https:\/\/doi.org\/10.1111\/DTH.13439","journal-title":"Dermatol Ther"},{"key":"4582_CR77","first-page":"33","volume":"27","author":"R-D Romila","year":"2021","unstructured":"Romila R-D, Nastase A, Misailoaie DM, Horiceanu M-M, Statescu L, Stincanu A, Patrascu AI, Vata D, Gheuca-Solovastru L (2021) Psycho-social impact of dermatological conditions associated with psychiatric disorders. Bull Integr Psychiatry 27:33\u201346","journal-title":"Bull Integr Psychiatry"},{"key":"4582_CR78","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/J.COFS.2020.01.003","volume":"32","author":"U Roobab","year":"2020","unstructured":"Roobab U, Batool Z, Manzoor MF, Shabbir MA, Khan MR, Aadil RM (2020) Sources, formulations, advanced delivery and health benefits of probiotics. Curr Opin Food Sci 32:17\u201328. https:\/\/doi.org\/10.1016\/J.COFS.2020.01.003","journal-title":"Curr Opin Food Sci"},{"issue":"18","key":"4582_CR79","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1038\/s41575-021-00440-6","volume":"18","author":"S Salminen","year":"2021","unstructured":"Salminen S, Collado MC, Endo A, Hill C, Lebeer S, Quigley EMM, Sanders ME, Shamir R, Swann JR, Szajewska H, Vinderola G (2021) The international scientific association of probiotics and prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics. Nat Rev Gastroenterol Hepatol 18(18):9. https:\/\/doi.org\/10.1038\/s41575-021-00440-6","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"1","key":"4582_CR80","doi-asserted-by":"publisher","DOI":"10.1002\/MNFR.201600240","volume":"61","author":"B S\u00e1nchez","year":"2017","unstructured":"S\u00e1nchez B, Delgado S, Blanco-M\u00edguez A, Louren\u00e7o A, Gueimonde M, Margolles A (2017) Probiotics, gut microbiota, and their influence on host health and disease. Mol Nutr Food Res 61(1):1600240. https:\/\/doi.org\/10.1002\/MNFR.201600240","journal-title":"Mol Nutr Food Res"},{"key":"4582_CR81","doi-asserted-by":"publisher","DOI":"10.3390\/MICROORGANISMS10071303","volume":"10","author":"P S\u00e1nchez-Pellicer","year":"2022","unstructured":"S\u00e1nchez-Pellicer P, Navarro-Moratalla L, N\u00fa\u00f1ez-Delegido E, Ruzafa-Costas B, Ag\u00fcera-Santos J, Navarro-L\u00f3pez V (2022) Acne, microbiome, and probiotics: the gut\u2013skin axis. Microorganisms 10:1303. https:\/\/doi.org\/10.3390\/MICROORGANISMS10071303","journal-title":"Microorganisms"},{"key":"4582_CR82","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1080\/10408398.2014.887055","volume":"57","author":"LK Sarao","year":"2017","unstructured":"Sarao LK, Arora M (2017) Probiotics, prebiotics, and microencapsulation: a review. Crit Rev Food Sci Nutr 57:344\u2013371. https:\/\/doi.org\/10.1080\/10408398.2014.887055","journal-title":"Crit Rev Food Sci Nutr"},{"key":"4582_CR83","doi-asserted-by":"publisher","first-page":"5092","DOI":"10.1111\/JOCD.14971","volume":"21","author":"S Sathikulpakdee","year":"2022","unstructured":"Sathikulpakdee S, Kanokrungsee S, Vitheejongjaroen P, Kamanamool N, Udompataikul M, Taweechotipatr M (2022) Efficacy of probiotic-derived lotion from Lactobacillus paracasei MSMC 39\u2009\u2013\u20091 in mild to moderate acne vulgaris, randomized controlled trial. J Cosmet Dermatol 21:5092\u20135097. https:\/\/doi.org\/10.1111\/JOCD.14971","journal-title":"J Cosmet Dermatol"},{"key":"4582_CR84","doi-asserted-by":"publisher","unstructured":"Sharma G, Khanna G, Sharma P, Deol PK, Kaur IP (2021) Mechanistic role of probiotics in improving skin health. Probiotic research in therapeutics: volume 3: probiotics and gut skin axis\u2013inside out and outside In 3: 27\u201347. https:\/\/doi.org\/10.1007\/978-981-16-5628-6_2","DOI":"10.1007\/978-981-16-5628-6_2"},{"key":"4582_CR85","doi-asserted-by":"publisher","DOI":"10.1016\/J.EJPS.2020.105563","volume":"156","author":"JA Silva","year":"2021","unstructured":"Silva JA, De Gregorio PR, Rivero G, Abraham GA, Nader-Mac\u00edas MEF (2021) Immobilization of vaginal Lactobacillus in polymeric nanofibers for its incorporation in vaginal probiotic products. Eur J Pharm Sci 156:105563. https:\/\/doi.org\/10.1016\/J.EJPS.2020.105563","journal-title":"Eur J Pharm Sci"},{"key":"4582_CR86","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.00130","author":"S Stojanov","year":"2020","unstructured":"Stojanov S, Berlec A (2020) Electrospun nanofibers as carriers of microorganisms, stem cells, proteins, and nucleic acids in therapeutic and other applications. Front Bioeng Biotechnol. https:\/\/doi.org\/10.3389\/fbioe.2020.00130","journal-title":"Front Bioeng Biotechnol"},{"key":"4582_CR87","doi-asserted-by":"publisher","first-page":"1127704","DOI":"10.3389\/FIMMU.2023.1127704\/BIBTEX","volume":"14","author":"M Strzelec","year":"2023","unstructured":"Strzelec M, Detka J, Mieszczak P, Soboci\u0144ska MK, Majka M (2023) Immunomodulation\u2014a general review of the current state-of-the-art and new therapeutic strategies for targeting the immune system. Front Immunol 14:1127704. https:\/\/doi.org\/10.3389\/FIMMU.2023.1127704\/BIBTEX","journal-title":"Front Immunol"},{"key":"4582_CR88","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2147\/JEP.S498769","volume":"17","author":"IAMP Sutema","year":"2025","unstructured":"Sutema IAMP, Latarissa IR, Widowati IGAR, Sartika CR, Ciptasari NWE, Lestari K (2025) Efficacy of probiotic supplements and topical applications in the treatment of acne: a scoping review of current results. J Exp Pharmacol 17:1\u201314. https:\/\/doi.org\/10.2147\/JEP.S498769","journal-title":"J Exp Pharmacol"},{"key":"4582_CR89","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.1111\/EXD.14016","volume":"28","author":"M Sz\u00e1nt\u00f3","year":"2019","unstructured":"Sz\u00e1nt\u00f3 M, D\u00f3zsa A, Antal D, Szab\u00f3 K, Kem\u00e9ny L, Bai P (2019) Targeting the gut-skin axis\u2014probiotics as new tools for skin disorder management? Exp Dermatol 28:1210\u20131218. https:\/\/doi.org\/10.1111\/EXD.14016","journal-title":"Exp Dermatol"},{"key":"4582_CR90","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1007\/S40257-018-0345-X","volume":"19","author":"MK Trivedi","year":"2018","unstructured":"Trivedi MK, Bosanac SS, Sivamani RK, Larsen LN (2018) Emerging therapies for acne vulgaris. Am J Clin Dermatol 19:505\u2013516. https:\/\/doi.org\/10.1007\/S40257-018-0345-X","journal-title":"Am J Clin Dermatol"},{"key":"4582_CR91","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.7150\/IJMS.51545","volume":"18","author":"WH Tsai","year":"2021","unstructured":"Tsai WH, Chou CH, Chiang YJ, Lin CG, Lee CH (2021) Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome. Int J Med Sci 18:1114\u20131120. https:\/\/doi.org\/10.7150\/IJMS.51545","journal-title":"Int J Med Sci"},{"key":"4582_CR92","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s10880-019-09640-4","volume":"27","author":"S Tugnoli","year":"2020","unstructured":"Tugnoli S, Agnoli C, Silvestri \u00b7, Giari A, Bettoli S, Caracciolo V, S (2020) Anger, emotional fragility, self-esteem, and psychiatric comorbidity in patients with hidradenitis suppurativa\/acne inversa. Springer 27:527\u2013540. https:\/\/doi.org\/10.1007\/s10880-019-09640-4","journal-title":"Springer"},{"key":"4582_CR97","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2020.1831339","author":"WF van Zyl","year":"2020","unstructured":"van Zyl WF, Deane SM, Dicks LMT (2020) Molecular insights into probiotic mechanisms of action employed against intestinal pathogenic bacteria. Gut Microbes. https:\/\/doi.org\/10.1080\/19490976.2020.1831339","journal-title":"Gut Microbes"},{"issue":"12","key":"4582_CR93","doi-asserted-by":"publisher","DOI":"10.1002\/ANBR.202100118","volume":"1","author":"AM Vargason","year":"2021","unstructured":"Vargason AM, Anselmo AC (2021) Live biotherapeutic products and probiotics for the skin. Adv NanoBiomed Res 1(12):2100118. https:\/\/doi.org\/10.1002\/ANBR.202100118","journal-title":"Adv NanoBiomed Res"},{"key":"4582_CR94","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.989563","volume":"13","author":"A Visciglia","year":"2022","unstructured":"Visciglia A, Allesina S, Amoruso A, De Prisco A, Dhir R, Bron PA, Pane M (2022) Assessment of shelf-life and metabolic viability of a multi-strain synbiotic using standard and innovative enumeration technologies. Front Microbiol 13:989563. https:\/\/doi.org\/10.3389\/fmicb.2022.989563","journal-title":"Front Microbiol"},{"key":"4582_CR98","doi-asserted-by":"publisher","DOI":"10.1002\/9781119593058.CH17","author":"A Von Wright","year":"2020","unstructured":"Von Wright A (2020) Regulatory aspects of probiotics and other microbial products intended for skin care. Skin Microb Handbook: Basic Res Product Dev. https:\/\/doi.org\/10.1002\/9781119593058.CH17","journal-title":"Skin Microb Handbook: Basic Res Product Dev"},{"issue":"8","key":"4582_CR95","doi-asserted-by":"publisher","first-page":"Page90","DOI":"10.3390\/COSMETICS8030090","volume":"2021","author":"C Wallen-Russell","year":"2021","unstructured":"Wallen-Russell C, Wallen-Russell S (2021) Topical probiotics do not satisfy new criteria for effective use due to insufficient skin Microbiome knowledge. Cosmetics 2021(8):Page90\u2013890. https:\/\/doi.org\/10.3390\/COSMETICS8030090","journal-title":"Cosmetics"},{"key":"4582_CR96","doi-asserted-by":"publisher","first-page":"126912","DOI":"10.1016\/J.MICRES.2021.126912","volume":"254","author":"M Wei","year":"2022","unstructured":"Wei M, ping, Yu H, Guo Y, hui, Cheng Y, liang, Xie Y, fei, Yao W, rong (2022) Synergistic combination of Sapindoside A and B: A novel antibiofilm agent against Cutibacterium acnes. Microbiol Res 254:126912. https:\/\/doi.org\/10.1016\/J.MICRES.2021.126912","journal-title":"Microbiol Res"},{"key":"4582_CR99","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1007\/S00223-018-0395-3","volume":"102","author":"J Yan","year":"2018","unstructured":"Yan J, Charles JF (2018) Gut microbiota and IGF-1. Calcif Tissue Int 102:406\u2013414. https:\/\/doi.org\/10.1007\/S00223-018-0395-3","journal-title":"Calcif Tissue Int"},{"key":"4582_CR100","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2020.00450","author":"J Yang","year":"2020","unstructured":"Yang J, Yang H, Xu A, He L (2020) A review of advancement on influencing factors of acne: an emphasis on environment characteristics. Front Public Health. https:\/\/doi.org\/10.3389\/fpubh.2020.00450","journal-title":"Front Public Health"},{"key":"4582_CR101","doi-asserted-by":"publisher","first-page":"2943","DOI":"10.7150\/IJMS.60874","volume":"18","author":"J Yang","year":"2021","unstructured":"Yang J, Jia C, Yang J (2021) Designing nanoparticle-based drug delivery systems for precision medicine. Int J Med Sci 18:2943\u20132949. https:\/\/doi.org\/10.7150\/IJMS.60874","journal-title":"Int J Med Sci"},{"key":"4582_CR102","doi-asserted-by":"publisher","first-page":"e12797","DOI":"10.1111\/JFPP.12797","volume":"41","author":"L Yilmaz-Ersan","year":"2017","unstructured":"Yilmaz-Ersan L, Ozcan T, Akpinar-Bayizit A, Turan MA, Taskin MB (2017) Probiotic cream: viability of probiotic bacteria and chemical characterization. J Food Process Preserv 41:e12797. https:\/\/doi.org\/10.1111\/JFPP.12797","journal-title":"J Food Process Preserv"},{"key":"4582_CR103","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/J.COFS.2020.03.009","volume":"32","author":"F Zendeboodi","year":"2020","unstructured":"Zendeboodi F, Khorshidian N, Mortazavian AM, da Cruz AG (2020) Probiotic: conceptualization from a new approach. Curr Opin Food Sci 32:103\u2013123. https:\/\/doi.org\/10.1016\/J.COFS.2020.03.009","journal-title":"Curr Opin Food Sci"},{"key":"4582_CR104","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1016\/j.cell.2018.08.041","volume":"174","author":"N Zmora","year":"2018","unstructured":"Zmora N, Zilberman-Schapira G, Suez J, Mor U, Dori-Bachash M, Bashiardes S, Kotler E, Zur M, Regev-Lehavi D, Brik RBZ, Federici S, Cohen Y, Linevsky R, Rothschild D, Moor AE, Ben-Moshe S, Harmelin A, Itzkovitz S, Maharshak N, Shibolet O, Shapiro H, Pevsner-Fischer M, Sharon I, Halpern Z, Segal E, Elinav E (2018) Personalized gut mucosal colonization resistance to empiric probiotics is associated with unique host and microbiome features. Cell 174:1388-1405e21. https:\/\/doi.org\/10.1016\/j.cell.2018.08.041","journal-title":"Cell"}],"container-title":["Archives of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00203-025-04582-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00203-025-04582-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00203-025-04582-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T20:02:31Z","timestamp":1771272151000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00203-025-04582-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,20]]},"references-count":105,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["4582"],"URL":"https:\/\/doi.org\/10.1007\/s00203-025-04582-y","relation":{},"ISSN":["0302-8933","1432-072X"],"issn-type":[{"value":"0302-8933","type":"print"},{"value":"1432-072X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,20]]},"assertion":[{"value":"23 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 November 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 November 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"During the preparation of this work the author(s) used [ChatGPT] in order to ensure the outline and readability of the review. After using this tool, the authors reviewed and edited the content as needed and takes full responsibility for the content of the publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"<!--Emphasis Type='Bold' removed-->Generative AI and AI-assisted technologies in the writing process"}}],"article-number":"27"}}