{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T10:19:35Z","timestamp":1793441975473,"version":"4.5.0"},"reference-count":182,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T00:00:00Z","timestamp":1769990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T00:00:00Z","timestamp":1769990400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Manipal Academy of Higher Education, Manipal"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Microbiol"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Acinetobacter baumannii<\/jats:italic>\n                    is a Gram-negative opportunistic pathogen and a major cause of healthcare-associated infections, including ventilator-associated pneumonia, bacteraemia, meningitis, and urinary tract infections. Its persistence in hospital environments is due to its ability to survive desiccation, resist disinfectants, and colonize both biotic and abiotic surfaces. Virulence in\n                    <jats:italic>A. baumannii<\/jats:italic>\n                    is largely associated with structures such as Csu pili, biofilm-associated protein (Bap), and outer membrane protein A (OmpA), which enable surface attachment, biofilm formation, and host cell damage. The production of extracellular polysaccharides and quorum sensing further enhance biofilm development. Iron uptake systems support bacterial growth even under iron-limited conditions within the host. Resistance to polymyxins often results from lipid A modifications regulated by the PmrCAB operon and\n                    <jats:italic>LpxL<\/jats:italic>\n                    -related genes, which also reduce immune recognition via the TLR4 pathway. Phase variation allows phenotypic changes that aid immune evasion. The highly adaptable genome of\n                    <jats:italic>A. baumannii<\/jats:italic>\n                    enables rapid acquisition of multiple resistance determinants, including OXA-type carbapenemases, efflux pumps, and aminoglycoside-modifying enzymes. Due to its extensive multidrug resistance, the World Health Organization lists\n                    <jats:italic>A. baumannii<\/jats:italic>\n                    as a critical-priority pathogen. This review aims to comprehensively examine the molecular mechanisms driving its virulence and resistance, highlighting potential therapeutic targets and strategies to combat this formidable pathogen.\n                  <\/jats:p>","DOI":"10.1007\/s00203-025-04668-7","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T08:03:26Z","timestamp":1770019406000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Virulence arsenal of Acinetobacter baumannii: mechanisms driving persistence and resistance"],"prefix":"10.1007","volume":"208","author":[{"given":"K.","family":"Ayswarya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6862-1944","authenticated-orcid":false,"given":"Rafwana","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vimal V.","family":"Veetilvalappil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishanth B.","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7666-3252","authenticated-orcid":false,"given":"Jesil Mathew","family":"Aranjani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,2]]},"reference":[{"key":"4668_CR180","doi-asserted-by":"publisher","unstructured":"Ababneh Q, Al Sbei S, Jaradat Z, Syaj S, Aldaken N, Ababneh H,  Inaya Z (2023) Extensively drug-resistant Acinetobacter baumannii: role of conjugative plasmids in transferring resistance. PeerJ 11:e14709. https:\/\/doi.org\/10.7717\/peerj.14709","DOI":"10.7717\/peerj.14709"},{"key":"4668_CR1","doi-asserted-by":"publisher","first-page":"423","DOI":"10.2147\/IDR.S228089","volume":"13","author":"SN Abdi","year":"2020","unstructured":"Abdi SN, Ghotaslou R, Ganbarov K, Mobed A, Tanomand A, Yousefi M, Asgharzadeh M, Kafil HS (2020) Acinetobacter baumannii efflux pumps and antibiotic resistance. Infect Drug Resist 13:423\u2013434. https:\/\/doi.org\/10.2147\/IDR.S228089","journal-title":"Infect Drug Resist"},{"key":"4668_CR182","doi-asserted-by":"publisher","unstructured":"Abed ES, Ali MR (2024) Identification of class I, II, and III Integron genes in multidrug-resistant Acinetobacter baumannii strains. J Appl Nat Sci 16(2):874\u2013882. https:\/\/doi.org\/10.31018\/jans.v16i2.5519","DOI":"10.31018\/jans.v16i2.5519"},{"issue":"9","key":"4668_CR2","doi-asserted-by":"publisher","first-page":"3569","DOI":"10.1128\/AAC.00057-10","volume":"54","author":"MD Adams","year":"2010","unstructured":"Adams MD, Chan ER, Molyneaux ND, Bonomo RA (2010) Genomewide analysis of divergence of antibiotic resistance determinants in closely related isolates of Acinetobacter baumannii. Antimicrob Agents Chemother 54(9):3569\u20133577. https:\/\/doi.org\/10.1128\/AAC.00057-10","journal-title":"Antimicrob Agents Chemother"},{"key":"4668_CR3","doi-asserted-by":"publisher","DOI":"10.1038\/S41598-020-58522-5","author":"I Ahmad","year":"2020","unstructured":"Ahmad I, Nygren E, Khalid F, Myint SL, Uhlin BE (2020) A cyclic-di-GMP signalling network regulates biofilm formation and surface associated motility of Acinetobacter baumannii. Sci Rep. https:\/\/doi.org\/10.1038\/S41598-020-58522-5","journal-title":"Sci Rep"},{"issue":"5","key":"4668_CR4","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1159\/000522232","volume":"14","author":"L Akoolo","year":"2022","unstructured":"Akoolo L, Pires S, Kim J, Parker D (2022) The capsule of Acinetobacter baumannii protects against the innate immune response. J Innate Immun 14(5):543\u2013554. https:\/\/doi.org\/10.1159\/000522232","journal-title":"J Innate Immun"},{"issue":"3","key":"4668_CR5","first-page":"167","volume":"7","author":"C Alexander","year":"2001","unstructured":"Alexander C, Rietschel ET (2001) Bacterial lipopolysaccharides and innate immunity. J Endotoxin Res 7(3):167\u2013202","journal-title":"J Endotoxin Res"},{"key":"4668_CR6","doi-asserted-by":"publisher","unstructured":"Ali A, Soares SC, Barbosa E, Santos AR, Barh D, Bakhtiar SM, Hassan S, Ussery D, Silva A, Miyoshi A (2013) Microbial comparative genomics: an overview of tools and insights into the genus Corynebacterium. J Bacteriol Parasitol. 4:167. https:\/\/doi.org\/10.4172\/2155-9597.1000167","DOI":"10.4172\/2155-9597.1000167"},{"issue":"8","key":"4668_CR7","doi-asserted-by":"publisher","first-page":"3743","DOI":"10.1128\/aac.00256-11","volume":"55","author":"LA Arroyo","year":"2011","unstructured":"Arroyo LA, Herrera CM, Fernandez L, Hankins JV, Trent MS, Hancock REW (2011a) The pmrCAB operon mediates polymyxin resistance in Acinetobacter baumannii ATCC 17978 and clinical isolates through phosphoethanolamine modification of lipid A. Antimicrob Agents Chemother 55(8):3743\u20133751. https:\/\/doi.org\/10.1128\/aac.00256-11","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"4668_CR8","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9030119","volume":"9","author":"C Ayoub Moubareck","year":"2020","unstructured":"Ayoub Moubareck C, Hammoudi Halat D (2020) Insights into Acinetobacter baumannii: a review of microbiological, virulence, and resistance traits in a threatening nosocomial pathogen. Antibiotics 9(3):119. https:\/\/doi.org\/10.3390\/antibiotics9030119","journal-title":"Antibiotics"},{"issue":"2","key":"4668_CR9","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.mib.2006.02.008","volume":"9","author":"S Backert","year":"2006","unstructured":"Backert S, Meyer TF (2006) Type IV secretion systems and their effectors in bacterial pathogenesis. Curr Opin Microbiol 9(2):207\u2013217. https:\/\/doi.org\/10.1016\/j.mib.2006.02.008","journal-title":"Curr Opin Microbiol"},{"issue":"1","key":"4668_CR10","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1128\/AAC.01597-13","volume":"58","author":"A Beceiro","year":"2014","unstructured":"Beceiro A, Moreno A, Fern\u00e1ndez N, Vallejo JA, Aranda J, Adler B, Harper M, Boyce JD, Bou G (2014) Biological cost of different mechanisms of colistin resistance and their impact on virulence in Acinetobacter baumannii. Antimicrob Agents Chemother 58(1):518. https:\/\/doi.org\/10.1128\/AAC.01597-13","journal-title":"Antimicrob Agents Chemother"},{"key":"4668_CR11","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/5419874","volume":"2022","author":"A Bharadwaj","year":"2022","unstructured":"Bharadwaj A, Rastogi A, Pandey S, Gupta S, Sohal JS (2022) Multidrug-resistant bacteria: their mechanism of action and prophylaxis. Biomed Res Int 2022:5419874. https:\/\/doi.org\/10.1155\/2022\/5419874","journal-title":"Biomed Res Int"},{"issue":"4","key":"4668_CR12","doi-asserted-by":"publisher","first-page":"349","DOI":"10.3109\/1040841X.2010.512269","volume":"36","author":"N Bhargava","year":"2010","unstructured":"Bhargava N, Sharma P, Capalash N (2010) Quorum sensing in acinetobacter: an emerging pathogen. Crit Rev Microbiol 36(4):349\u2013360. https:\/\/doi.org\/10.3109\/1040841X.2010.512269","journal-title":"Crit Rev Microbiol"},{"issue":"2","key":"4668_CR13","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.03025-24","volume":"16","author":"S Bhowmik","year":"2025","unstructured":"Bhowmik S, Pathak A, Pandey S, Devnath K, Sett A, Jyoti N, Bhando T, Akhter J, Chugh S, Singh R, Sharma TK, Pathania R (2025) Acinetobacter baumannii represses type VI secretion system through a manganese-dependent small RNA-mediated regulation. mBio 16(2):e0302524. https:\/\/doi.org\/10.1128\/mbio.03025-24","journal-title":"mBio"},{"issue":"3","key":"4668_CR14","doi-asserted-by":"publisher","first-page":"e00349","DOI":"10.1128\/MSPHERE.00349-20","volume":"5","author":"D Bi","year":"2020","unstructured":"Bi D, Zheng J, Xie R, Zhu Y, Wei R, Ou H-Y, Wei Q, Qin H (2020) Comparative analysis of AbaR-Type genomic Islands reveals distinct patterns of genetic features in elements with different backbones. mSphere 5(3):e00349\u2013e00320. https:\/\/doi.org\/10.1128\/MSPHERE.00349-20","journal-title":"mSphere"},{"issue":"4","key":"4668_CR15","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1007\/s00284-021-02407-x","volume":"78","author":"U Blaschke","year":"2021","unstructured":"Blaschke U, Skiebe E, Wilharm G (2021) Novel genes required for Surface-Associated motility in Acinetobacter baumannii. Curr Microbiol 78(4):1509\u20131528. https:\/\/doi.org\/10.1007\/s00284-021-02407-x","journal-title":"Curr Microbiol"},{"issue":"1","key":"4668_CR16","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1128\/IAI.05913-11","volume":"80","author":"KA Brossard","year":"2012","unstructured":"Brossard KA, Campagnari AA (2012) The Acinetobacter baumannii Biofilm-Associated protein plays a role in adherence to human epithelial cells. Infect Immun 80(1):228. https:\/\/doi.org\/10.1128\/IAI.05913-11","journal-title":"Infect Immun"},{"issue":"5","key":"4668_CR17","doi-asserted-by":"publisher","first-page":"e0125832","DOI":"10.1371\/journal.pone.0125832","volume":"10","author":"JR Brown","year":"2015","unstructured":"Brown JR, Livesay DR (2015) Flexibility correlation between active site regions is conserved across four AmpC \u03b2-Lactamase enzymes. PLoS ONE 10(5):e0125832. https:\/\/doi.org\/10.1371\/journal.pone.0125832","journal-title":"PLoS ONE"},{"issue":"Pt 9","key":"4668_CR18","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1099\/JMM.0.020339-0","volume":"59","author":"K Cardoso","year":"2010","unstructured":"Cardoso K, Gandra RF, Wisniewski ES, Osaku CA, Kadowaki MK, Felipach-Neto V, Haus LFA\u00c1, Sim\u00e3o RDCG (2010) DnaK and GroEL are induced in response to antibiotic and heat shock in Acinetobacter baumannii. J Med Microbiol 59(Pt 9):1061\u20131068. https:\/\/doi.org\/10.1099\/JMM.0.020339-0","journal-title":"J Med Microbiol"},{"issue":"1","key":"4668_CR19","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1080\/21505594.2018.1460187","volume":"9","author":"M Carretero-Ledesma","year":"2018","unstructured":"Carretero-Ledesma M, Garc\u00eda-Quintanilla M, Mart\u00edn-Pe\u00f1a R, Pulido MR, Pach\u00f3n J, McConnell MJ (2018) Phenotypic changes associated with Colistin resistance due to Lipopolysaccharide loss in Acinetobacter baumannii. Virulence 9(1):930\u2013942. https:\/\/doi.org\/10.1080\/21505594.2018.1460187","journal-title":"Virulence"},{"issue":"3","key":"4668_CR20","doi-asserted-by":"publisher","first-page":"e59388","DOI":"10.1371\/JOURNAL.PONE.0059388","volume":"8","author":"MD Carruthers","year":"2013","unstructured":"Carruthers MD, Nicholson PA, Tracy EN, Munson RS (2013) Acinetobacter baumannii utilizes a type VI secretion system for bacterial competition. PLoS One 8(3):e59388. https:\/\/doi.org\/10.1371\/JOURNAL.PONE.0059388","journal-title":"PLoS One"},{"issue":"2","key":"4668_CR21","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1007\/S10534-006-0003-2","volume":"19","author":"ML Cartron","year":"2006","unstructured":"Cartron ML, Maddocks S, Gillingham P, Craven CJ, Andrews SC (2006) Feo\u2014transport of ferrous iron into bacteria. Biometals 19(2):143\u2013157. https:\/\/doi.org\/10.1007\/S10534-006-0003-2","journal-title":"Biometals"},{"key":"4668_CR22","doi-asserted-by":"publisher","first-page":"1196774","DOI":"10.3389\/fmicb.2023.1196774","volume":"14","author":"I Cavallo","year":"2023","unstructured":"Cavallo I, Oliva A, Pages R, Sivori F, Truglio M, Fabrizio G, Pasqua M, Pimpinelli F, Di Domenico EG (2023) Acinetobacter baumannii in the critically ill: complex infections get complicated. Front Microbiol 14:1196774. https:\/\/doi.org\/10.3389\/fmicb.2023.1196774","journal-title":"Front Microbiol"},{"key":"4668_CR23","doi-asserted-by":"publisher","first-page":"919","DOI":"10.3389\/FMICB.2020.00919","volume":"11","author":"M Cerezales","year":"2020","unstructured":"Cerezales M, Xanthopoulou K, Wille J, Krut O, Seifert H, Gallego L, Higgins PG (2020) Mobile genetic elements harboring antibiotic resistance determinants in Acinetobacter baumannii isolates from Bolivia. Front Microbiol 11:919. https:\/\/doi.org\/10.3389\/FMICB.2020.00919","journal-title":"Front Microbiol"},{"issue":"7","key":"4668_CR24","doi-asserted-by":"publisher","DOI":"10.3390\/covid40700921","volume":"4","author":"T Chaaban","year":"2024","unstructured":"Chaaban T, Ezzeddine Z, Ghssein G (2024) Antibiotic misuse during the COVID-19 pandemic in Lebanon: a cross-sectional study. COVID 4(7):921. https:\/\/doi.org\/10.3390\/covid40700921","journal-title":"COVID"},{"issue":"Pt 9","key":"4668_CR25","doi-asserted-by":"publisher","first-page":"2534","DOI":"10.1099\/MIC.0.049791-0","volume":"157","author":"KM Clemmer","year":"2011","unstructured":"Clemmer KM, Bonomo RA, Rather PN (2011) Genetic analysis of surface motility in Acinetobacter baumannii. Microbiology 157(Pt 9):2534\u20132544. https:\/\/doi.org\/10.1099\/MIC.0.049791-0","journal-title":"Microbiology"},{"issue":"10","key":"4668_CR26","doi-asserted-by":"publisher","first-page":"e00223","DOI":"10.1128\/iai.00223-22","volume":"90","author":"S Cook-Libin","year":"2022","unstructured":"Cook-Libin S, Sykes EME, Kornelsen V, Kumar A (2022) Iron acquisition mechanisms and their role in the virulence of Acinetobacter baumannii. Infect Immun 90(10):e00223\u2013e00222. https:\/\/doi.org\/10.1128\/iai.00223-22","journal-title":"Infect Immun"},{"issue":"1","key":"4668_CR27","doi-asserted-by":"publisher","first-page":"2201","DOI":"10.1080\/21505594.2021.1950268","volume":"12","author":"J Corral","year":"2021","unstructured":"Corral J, P\u00e9rez-Varela M, S\u00e1nchez-Osuna M, Cort\u00e9s P, Barb\u00e9 J, Aranda J (2021) Importance of twitching and surface-associated motility in the virulence of Acinetobacter baumannii. Virulence 12(1):2201\u20132213. https:\/\/doi.org\/10.1080\/21505594.2021.1950268","journal-title":"Virulence"},{"issue":"6","key":"4668_CR28","doi-asserted-by":"publisher","first-page":"3180","DOI":"10.1093\/NAR\/GKAE129","volume":"52","author":"A Correa","year":"2024","unstructured":"Correa A, Shehreen S, Machado LC, Thesier J, Cunic LM, Petassi MT, Chu J, Kapili BJ, Jia Y, England KA, Peters JE (2024) Novel mechanisms of diversity generation in Acinetobacter baumannii resistance islands driven by Tn7-like elements. Nucleic Acids Res 52(6):3180\u20133198. https:\/\/doi.org\/10.1093\/NAR\/GKAE129","journal-title":"Nucleic Acids Res"},{"issue":"10","key":"4668_CR29","doi-asserted-by":"publisher","first-page":"4389","DOI":"10.1128\/AAC.00155-10","volume":"54","author":"S Coyne","year":"2010","unstructured":"Coyne S, Rosenfeld N, Lambert T, Courvalin P, P\u00e9richon B (2010) Overexpression of resistance-nodulation-cell division pump AdeFGH confers multidrug resistance in Acinetobacter baumannii. Antimicrob Agents Chemother 54(10):4389\u20134393. https:\/\/doi.org\/10.1128\/AAC.00155-10","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"4668_CR30","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1128\/AAC.01388-10","volume":"55","author":"S Coyne","year":"2011","unstructured":"Coyne S, Courvalin P, P\u00e9richon B (2011) Efflux-mediated antibiotic resistance in acinetobacter spp. Antimicrob Agents Chemother 55(3):947\u2013953. https:\/\/doi.org\/10.1128\/AAC.01388-10","journal-title":"Antimicrob Agents Chemother"},{"issue":"5","key":"4668_CR31","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1038\/NRMICRO885","volume":"2","author":"L Craig","year":"2004","unstructured":"Craig L, Pique ME, Tainer JA (2004) Type IV pilus structure and bacterial pathogenicity. Nat Rev Microbiol 2(5):363\u2013378. https:\/\/doi.org\/10.1038\/NRMICRO885","journal-title":"Nat Rev Microbiol"},{"key":"4668_CR32","doi-asserted-by":"publisher","first-page":"2168","DOI":"10.1016\/J.CSBJ.2025.05.032","volume":"27","author":"B Cui","year":"2025","unstructured":"Cui B, Peng G, Wang LE, Deng Y (2025) Signaling in Acinetobacter baumannii: quorum sensing and nucleotide second messengers. Comput Struct Biotechnol J 27:2168\u20132175. https:\/\/doi.org\/10.1016\/J.CSBJ.2025.05.032","journal-title":"Comput Struct Biotechnol J"},{"key":"4668_CR178","doi-asserted-by":"publisher","unstructured":"Dalbanjan NP, Kadapure AJ,  Praveen Kumar SK (2024) A comprehensive review on latent role of stress proteins in antibiotic resistance. The Microbe 4:100151. https:\/\/doi.org\/10.1016\/j.microb.2024.100151","DOI":"10.1016\/j.microb.2024.100151"},{"issue":"2","key":"4668_CR33","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1128\/AAC.00732-07\/ASSET\/8F4FE06F-AE14-4739-AC6D-43770ACD11D8\/ASSETS\/GRAPHIC\/ZAC0020870690002.JPEG","volume":"52","author":"L Damier-Piolle","year":"2008","unstructured":"Damier-Piolle L, Magnet S, Br\u00e9mont S, Lambert T, Courvalin P (2008) AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. Antimicrob Agents Chemother 52(2):557\u2013562. https:\/\/doi.org\/10.1128\/AAC.00732-07\/ASSET\/8F4FE06F-AE14-4739-AC6D-43770ACD11D8\/ASSETS\/GRAPHIC\/ZAC0020870690002.JPEG","journal-title":"Antimicrob Agents Chemother"},{"issue":"27","key":"4668_CR34","doi-asserted-by":"publisher","first-page":"40507","DOI":"10.1007\/S11356-022-19840-5","volume":"29","author":"S Das","year":"2022","unstructured":"Das S, Bombaywala S, Srivastava S, Kapley A, Dhodapkar R, Dafale NA (2022) Genome plasticity as a paradigm of antibiotic resistance spread in ESKAPE pathogens. Environ Sci Pollut Res Int 29(27):40507\u201340519. https:\/\/doi.org\/10.1007\/S11356-022-19840-5","journal-title":"Environ Sci Pollut Res Int"},{"key":"4668_CR35","doi-asserted-by":"publisher","DOI":"10.1186\/s40793-016-0158-6","volume":"11","author":"EL de Aguiar","year":"2016","unstructured":"de Aguiar EL, Mariano DC, Viana MV, Benevides LdeJ, de Souza Rocha F, de Castro Oliveira L, Pereira FL, Dorella FA, Leal CA, de Carvalho AF, Santos GS, Mattos-Guaraldi AL, Nagao PE, de Castro Soares S, Hassan SS, Pinto AC, Figueiredo HC, Azevedo V (2016) Complete genome sequence of Streptococcus agalactiae strain GBS85147 serotype of type Ia isolated from human oropharynx. Stand Genomic Sci 11:39. https:\/\/doi.org\/10.1186\/s40793-016-0158-6","journal-title":"Stand Genomic Sci"},{"issue":"7","key":"4668_CR36","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms13071501","volume":"13","author":"J de Souza","year":"2025","unstructured":"de Souza J, D\u2019Espindula HRS, Ribeiro IF, Gon\u00e7alves GA, Pillonetto M, Faoro H (2025) Carbapenem Resistance in Acinetobacter baumannii: mechanisms, therapeutics, and innovations. Microorganisms 13(7):1501. https:\/\/doi.org\/10.3390\/microorganisms13071501","journal-title":"Microorganisms"},{"key":"4668_CR181","doi-asserted-by":"publisher","unstructured":"Deylam Salehi M, Ferdosi-Shahandashti E, Yahyapour Y, Khafri S, Pournajaf A,  Rajabnia R (2017) Integron-Mediated Antibiotic Resistance in Acinetobacter baumannii Isolated from Intensive Care Unit Patients, Babol, North of Iran. BioMed Res Int 7157923. https:\/\/doi.org\/10.1155\/2017\/7157923","DOI":"10.1155\/2017\/7157923"},{"issue":"7","key":"4668_CR37","doi-asserted-by":"publisher","first-page":"2623","DOI":"10.1073\/pnas.1222783110","volume":"110","author":"TG Dong","year":"2013","unstructured":"Dong TG, Ho BT, Yoder-Himes DR, Mekalanos JJ (2013) Identification of T6SS-dependent effector and immunity proteins by Tn-seq in vibrio cholerae. Proc Natl Acad Sci USA 110(7):2623\u20132628. https:\/\/doi.org\/10.1073\/pnas.1222783110","journal-title":"Proc Natl Acad Sci USA"},{"key":"4668_CR38","doi-asserted-by":"crossref","unstructured":"Elkheloui R, Laktib A, Mimouni R, Aitalla A, Hassi M, Elboulani A, Hamadi F (2020) Acinetobacter baumannii biofilm: intervening Factors, Persistence, drug Resistance, and strategies of treatment. Mediterranean J Infect Microb Antimicrob. p 9","DOI":"10.4274\/mjima.galenos.2020.2020.7"},{"key":"4668_CR39","doi-asserted-by":"publisher","first-page":"558003","DOI":"10.3389\/FMICB.2021.558003","volume":"12","author":"BA Evans","year":"2021","unstructured":"Evans BA, Zhou J, Zhong S, He S (2021) Quorum sensing inhibition or quenching in Acinetobacter baumannii: the novel therapeutic strategies for new drug development. Front Microbiol 12:558003. https:\/\/doi.org\/10.3389\/FMICB.2021.558003","journal-title":"Front Microbiol"},{"key":"4668_CR40","doi-asserted-by":"publisher","first-page":"2277","DOI":"10.2147\/IDR.S169894","volume":"11","author":"EC Eze","year":"2018","unstructured":"Eze EC, Chenia HY, Zowalaty MEE (2018) Acinetobacter baumannii biofilms: effects of physicochemical factors, virulence, antibiotic resistance determinants, gene regulation, and future antimicrobial treatments. Infect Drug Resist 11:2277. https:\/\/doi.org\/10.2147\/IDR.S169894","journal-title":"Infect Drug Resist"},{"issue":"10","key":"4668_CR41","doi-asserted-by":"publisher","first-page":"e0205638","DOI":"10.1371\/JOURNAL.PONE.0205638","volume":"13","author":"JM Farrow","year":"2018","unstructured":"Farrow JM, Wells G, Pesci EC (2018) Desiccation tolerance in Acinetobacter baumannii is mediated by the two-component response regulator BfmR. PLoS One 13(10):e0205638. https:\/\/doi.org\/10.1371\/JOURNAL.PONE.0205638","journal-title":"PLoS One"},{"issue":"6","key":"4668_CR42","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s00005-011-0144-z","volume":"59","author":"CK Ferrari","year":"2011","unstructured":"Ferrari CK, Souto PC, Fran\u00e7a EL, Honorio-Fran\u00e7a AC (2011) Oxidative and nitrosative stress on phagocytes\u2019 function: from effective defense to immunity evasion mechanisms. Arch Immunol Ther Exp 59(6):441\u2013448. https:\/\/doi.org\/10.1007\/s00005-011-0144-z","journal-title":"Arch Immunol Ther Exp"},{"key":"4668_CR43","doi-asserted-by":"publisher","unstructured":"Fiester SE, Arivett BA, Schmidt RE, Beckett AC, Ticak T, Carrier MV, Ghosh R, Ohneck EJ, Metz ML, Jeffries MKS, Actis LA (2016b) Iron-Regulated phospholipase C activity contributes to the cytolytic activity and virulence of Acinetobacter baumannii. PLoS ONE. https:\/\/doi.org\/10.1371\/JOURNAL.PONE.0167068","DOI":"10.1371\/JOURNAL.PONE.0167068"},{"key":"4668_CR44","doi-asserted-by":"publisher","unstructured":"Fitzsimons TC, Lewis JM, Wright A, Kleifeld O, Schittenhelm RB, Powell D, Harper M, Boyce JD (2018) Identification of novel Acinetobacter baumannii type VI secretion system antibacterial effector and immunity pairs. Infect Immun. https:\/\/doi.org\/10.1128\/IAI.00297-18\/SUPPL_FILE\/ZII999092468S1.PDF","DOI":"10.1128\/IAI.00297-18\/SUPPL_FILE\/ZII999092468S1.PDF"},{"key":"4668_CR187","doi-asserted-by":"publisher","unstructured":"Florencia Haurat M, Scott NE, Di Venanzio G, et al (2020) The glycoprotease CpaA secreted by medically relevant acinetobacter species targets multiple O-linked host glycoproteins. mBio 11:1\u201319. https:\/\/doi.org\/10.1128\/MBIO.02033-20\/SUPPL_FILE\/MBIO.02033-20-ST002.","DOI":"10.1128\/MBIO.02033-20\/SUPPL_FILE\/MBIO.02033-20-ST002."},{"issue":"6","key":"4668_CR46","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1159\/000515740","volume":"13","author":"RS Gabarin","year":"2021","unstructured":"Gabarin RS, Li M, Zimmel PA, Marshall JC, Li Y, Zhang H (2021) Intracellular and extracellular lipopolysaccharide signaling in sepsis: avenues for novel therapeutic strategies. J Innate Immun 13(6):323\u2013332. https:\/\/doi.org\/10.1159\/000515740","journal-title":"J Innate Immun"},{"issue":"3","key":"4668_CR47","doi-asserted-by":"publisher","first-page":"273","DOI":"10.2217\/fmb.09.5","volume":"4","author":"JA Gaddy","year":"2009","unstructured":"Gaddy JA, Actis LA (2009) Regulation of Acinetobacter baumannii biofilm formation. Future Microbiol 4(3):273\u2013278. https:\/\/doi.org\/10.2217\/fmb.09.5","journal-title":"Future Microbiol"},{"key":"4668_CR48","doi-asserted-by":"publisher","unstructured":"Gedefie A, Demsis W, Ashagrie M, Kassa Y, Tesfaye M, Tilahun M, Bisetegn H, Sahle Z (2021) Acinetobacter baumannii biofilm formation and its role in disease pathogenesis: A review. Infect Drug Resist. https:\/\/doi.org\/10.2147\/IDR.S332051","DOI":"10.2147\/IDR.S332051"},{"issue":"suppl1","key":"4668_CR49","doi-asserted-by":"publisher","first-page":"S9","DOI":"10.1093\/INFDIS\/JIW402","volume":"215","author":"E Geisinger","year":"2017","unstructured":"Geisinger E, Isberg RR (2017) Interplay between antibiotic resistance and virulence during disease promoted by multidrug-resistant bacteria. J Infect Dis 215(suppl1):S9\u2013S17. https:\/\/doi.org\/10.1093\/INFDIS\/JIW402","journal-title":"J Infect Dis"},{"issue":"5","key":"4668_CR50","doi-asserted-by":"publisher","first-page":"e1007030","DOI":"10.1371\/journal.ppat.1007030","volume":"14","author":"E Geisinger","year":"2018","unstructured":"Geisinger E, Mortman NJ, Vargas-Cuebas G, Tai AK, Isberg RR (2018) A global regulatory system links virulence and antibiotic resistance to envelope homeostasis in Acinetobacter baumannii. PLoS Pathog 14(5):e1007030. https:\/\/doi.org\/10.1371\/journal.ppat.1007030","journal-title":"PLoS Pathog"},{"key":"4668_CR51","doi-asserted-by":"publisher","unstructured":"Gr\u00e4ff \u00c1T, Barry SM (2024) Siderophores as tools and treatments. npj Antimicrob Resist. 2(1):47. https:\/\/doi.org\/10.1038\/s44259-024-00053-4","DOI":"10.1038\/s44259-024-00053-4"},{"key":"4668_CR183","doi-asserted-by":"publisher","unstructured":"Hamidian M,  Hall RM (2018) The AbaR antibiotic resistance islands found in Acinetobacter baumannii global clone 1 - Structure, origin and evolution. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 41:26\u201339. https:\/\/doi.org\/10.1016\/j.drup.2018.10.003","DOI":"10.1016\/j.drup.2018.10.003"},{"issue":"4","key":"4668_CR52","doi-asserted-by":"publisher","first-page":"e00360","DOI":"10.1128\/MBIO.00360-13","volume":"4","author":"CM Harding","year":"2013","unstructured":"Harding CM, Tracy EN, Carruthers MD, Rather PN, Actis LA, Munson RS (2013) Acinetobacter baumannii strain M2 produces type IV pili which play a role in natural transformation and twitching motility but not surface-associated motility. mBio 4(4):e00360\u2013e00313. https:\/\/doi.org\/10.1128\/MBIO.00360-13","journal-title":"mBio"},{"issue":"2","key":"4668_CR54","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1038\/nrmicro.2017.148","volume":"16","author":"CM Harding","year":"2018","unstructured":"Harding CM, Hennon SW, Feldman MF (2018) Uncovering the mechanisms of Acinetobacter baumannii virulence. Nat Rev Microbiol 16(2):91\u2013102. https:\/\/doi.org\/10.1038\/nrmicro.2017.148","journal-title":"Nat Rev Microbiol"},{"issue":"20","key":"4668_CR55","doi-asserted-by":"publisher","first-page":"5718","DOI":"10.1128\/JB.01373-12","volume":"194","author":"SS Hassan","year":"2012","unstructured":"Hassan SS, Schneider MP, Ramos RT, Carneiro AR, Ranieri A, Guimar\u00e3es LC, Ali A, Bakhtiar SM, Pereira UdeP, dos Santos AR, Soares SdeC, Dorella F, Pinto AC, Ribeiro D, Barbosa MS, Almeida S, Abreu V, Aburjaile F, Fiaux K, Barbosa E, Silva A (2012) Whole-genome sequence of Corynebacterium pseudotuberculosis strain Cp162, isolated from camel. J Bacteriol 194(20):5718\u20135719. https:\/\/doi.org\/10.1128\/JB.01373-12","journal-title":"J Bacteriol"},{"key":"4668_CR56","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/J.MIB.2021.08.005","volume":"64","author":"KA Hassan","year":"2021","unstructured":"Hassan KA, Maher C, Elbourne LD, Henderson PJ, Paulsen IT (2021) Increasing the PACE of characterising novel transporters by functional genomics. Curr Opin Microbiol 64:1\u20138. https:\/\/doi.org\/10.1016\/J.MIB.2021.08.005","journal-title":"Curr Opin Microbiol"},{"issue":"5","key":"4668_CR57","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1128\/MBIO.02033-20\/SUPPL_FILE\/MBIO.02033-20-ST002.PDF","volume":"11","author":"MF Haurat","year":"2020","unstructured":"Haurat MF, Scott NE, Venanzio GD, Lopez J, Pluvinage B, Boraston AB, Ferracane MJ, Feldman MF (2020) The glycoprotease CpaA secreted by medically relevant acinetobacter species targets multiple O-linked host glycoproteins. mBio 11(5):1\u201319. https:\/\/doi.org\/10.1128\/MBIO.02033-20\/SUPPL_FILE\/MBIO.02033-20-ST002.PDF","journal-title":"mBio"},{"key":"4668_CR58","doi-asserted-by":"publisher","unstructured":"Heindorf M, Kadari M, Heider C, Skiebe E, Wilharm G (2014) Impact of Acinetobacter baumannii superoxide dismutase on motility, virulence, oxidative stress resistance and susceptibility to antibiotics. PLoS ONE 9(7). https:\/\/doi.org\/10.1371\/JOURNAL.PONE.0101033","DOI":"10.1371\/JOURNAL.PONE.0101033"},{"issue":"1","key":"4668_CR59","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1128\/AAC.05191-11\/ASSET\/9587D656-7D0B-4E5F-BE0C-ECD094F6818D\/ASSETS\/GRAPHIC\/ZAC9991004790004.JPEG","volume":"56","author":"R Henry","year":"2012","unstructured":"Henry R, Vithanage N, Harrison P, Seemann T, Coutts S, Moffatt JH, Nation RL, Li J, Harper M, Adler B, Boyce JD (2012) Colistin-resistant, lipopolysaccharide-deficient Acinetobacter baumannii responds to lipopolysaccharide loss through increased expression of genes involved in the synthesis and transport of lipoproteins, phospholipids, and poly-\u03b2-1,6-N-acetylglucosamine. Antimicrob Agents Chemother 56(1):59\u201369. https:\/\/doi.org\/10.1128\/AAC.05191-11\/ASSET\/9587D656-7D0B-4E5F-BE0C-ECD094F6818D\/ASSETS\/GRAPHIC\/ZAC9991004790004.JPEG","journal-title":"Antimicrob Agents Chemother"},{"issue":"26","key":"4668_CR60","doi-asserted-by":"publisher","first-page":"9786","DOI":"10.1073\/pnas.0402521101","volume":"101","author":"MT Holden","year":"2004","unstructured":"Holden MT, Feil EJ, Lindsay JA, Peacock SJ, Day NP, Enright MC, Foster TJ, Moore CE, Hurst L, Atkin R, Barron A, Bason N, Bentley SD, Chillingworth C, Chillingworth T, Churcher C, Clark L, Corton C, Cronin A, Doggett J, Parkhill J (2004) Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci USA 101(26):9786\u20139791. https:\/\/doi.org\/10.1073\/pnas.0402521101","journal-title":"Proc Natl Acad Sci USA"},{"issue":"7","key":"4668_CR61","doi-asserted-by":"publisher","first-page":"e1010646","DOI":"10.1371\/JOURNAL.PGEN.1010646","volume":"19","author":"R Iruegas","year":"2023","unstructured":"Iruegas R, Pfefferle K, G\u00f6ttig S, Averhoff B, Ebersberger I (2023) Feature architecture aware phylogenetic profiling indicates a functional diversification of type IVa pili in the nosocomial pathogen Acinetobacter baumannii. PLoS Genet 19(7):e1010646. https:\/\/doi.org\/10.1371\/JOURNAL.PGEN.1010646","journal-title":"PLoS Genet"},{"key":"4668_CR62","doi-asserted-by":"publisher","unstructured":"Jeon JH, Jang KM, Lee JH, Kang LW, Lee SH (2023) Transmission of antibiotic resistance genes through mobile genetic elements in Acinetobacter baumannii and gene-transfer prevention. Sci Total Environ. https:\/\/doi.org\/10.1016\/J.SCITOTENV.2022.159497","DOI":"10.1016\/J.SCITOTENV.2022.159497"},{"issue":"1","key":"4668_CR63","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/S00253-023-12975-6\/TABLES\/3","volume":"108","author":"GJ Jeong","year":"2024","unstructured":"Jeong GJ, Khan F, Tabassum N, Kim YM (2024) Motility of Acinetobacter baumannii: regulatory systems and controlling strategies. Appl Microbiol Biotechnol 108(1):1\u201313. https:\/\/doi.org\/10.1007\/S00253-023-12975-6\/TABLES\/3","journal-title":"Appl Microbiol Biotechnol"},{"key":"4668_CR64","doi-asserted-by":"publisher","unstructured":"Jiang X, Yang K, Han ML, Yuan B, Li J, Gong B, Velkov T, Schreiber F, Wang L, Li J (2020) Outer membranes of Polymyxin-Resistant Acinetobacter baumannii with Phosphoethanolamine-Modified lipid A and lipopolysaccharide loss display different Atomic-Scale interactions with polymyxins. ACS Infect Dis. https:\/\/doi.org\/10.1021\/acsinfecdis.0c00330","DOI":"10.1021\/acsinfecdis.0c00330"},{"issue":"4","key":"4668_CR65","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1128\/JB.00622-15","volume":"198","author":"TL Johnson","year":"2016","unstructured":"Johnson TL, Waack U, Smith S, Mobley H, Sandkvist M (2016) Acinetobacter baumannii is dependent on the type II secretion system and its substrate LipA for lipid utilization and in vivo fitness. J Bacteriol 198(4):711\u2013719. https:\/\/doi.org\/10.1128\/JB.00622-15","journal-title":"J Bacteriol"},{"issue":"12","key":"4668_CR66","doi-asserted-by":"publisher","first-page":"2377","DOI":"10.1111\/j.1462-5822.2008.01187.x","volume":"10","author":"M Juhas","year":"2008","unstructured":"Juhas M, Crook DW, Hood DW (2008) Type IV secretion systems: tools of bacterial horizontal gene transfer and virulence. Cell Microbiol 10(12):2377\u20132386. https:\/\/doi.org\/10.1111\/j.1462-5822.2008.01187.x","journal-title":"Cell Microbiol"},{"issue":"1","key":"4668_CR67","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1186\/S12866-025-03806-X","volume":"25","author":"M Kakavan","year":"2025","unstructured":"Kakavan M, Gholami M, Ahanjan M, Ebrahimzadeh MA, Salehian M, Roozbahani F, Goli HR (2025) Expression of bap gene in multidrug-resistant and biofilm-producing Acinetobacter baumannii clinical isolates. BMC Microbiol 25(1):108. https:\/\/doi.org\/10.1186\/S12866-025-03806-X","journal-title":"BMC Microbiol"},{"key":"4668_CR68","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1146\/annurev-biochem-052909-141507","volume":"80","author":"JY Kang","year":"2011","unstructured":"Kang JY, Lee JO (2011) Structural biology of the Toll-like receptor family. Annu Rev Biochem 80:917\u2013941. https:\/\/doi.org\/10.1146\/annurev-biochem-052909-141507","journal-title":"Annu Rev Biochem"},{"key":"4668_CR69","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1016\/J.MICPATH.2017.08.001","volume":"110","author":"SM Kareem","year":"2017","unstructured":"Kareem SM, Al-Kadmy IMS, Al-Kaabi MH, Aziz SN, Ahmad M (2017) Acinetobacter baumannii virulence is enhanced by the combined presence of virulence factors genes phospholipase C (plcN) and elastase (lasB). Microb Pathog 110:568\u2013572. https:\/\/doi.org\/10.1016\/J.MICPATH.2017.08.001","journal-title":"Microb Pathog"},{"issue":"5","key":"4668_CR70","doi-asserted-by":"publisher","first-page":"e0224821","DOI":"10.1128\/mBio.02248-21","volume":"12","author":"M Kim","year":"2021","unstructured":"Kim M, Kim DY, Song WY, Park SE, Harrison SA, Chazin WJ, Oh MH, Kim HJ (2021) Distinctive roles of two acinetobactin isomers in challenging host nutritional immunity. mBio 12(5):e0224821. https:\/\/doi.org\/10.1128\/mBio.02248-21","journal-title":"mBio"},{"key":"4668_CR71","doi-asserted-by":"publisher","DOI":"10.3390\/IJMS232113136","author":"HJ Kim","year":"2022","unstructured":"Kim HJ, Kim NY, Ko SY, Park SY, Oh MH, Shin MS, Lee YC, Lee JC (2022a) Complementary regulation of BfmRS two-component and AbaIR quorum sensing systems to express virulence-associated genes in  Acinetobacter baumannii. Int J Mol Sci. https:\/\/doi.org\/10.3390\/IJMS232113136","journal-title":"Int J Mol Sci"},{"issue":"4","key":"4668_CR72","doi-asserted-by":"publisher","first-page":"e01295","DOI":"10.1128\/SPECTRUM.01295-22","volume":"10","author":"S-H Kim","year":"2022","unstructured":"Kim S-H, Yun S, Park W (2022b) Constitutive phenotypic modification of lipid A in clinical Acinetobacter baumannii isolates. Microbiol Spectr 10(4):e01295\u2013e01222. https:\/\/doi.org\/10.1128\/SPECTRUM.01295-22","journal-title":"Microbiol Spectr"},{"issue":"3","key":"4668_CR73","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1039\/d4cb00293h","volume":"6","author":"S Kim","year":"2025","unstructured":"Kim S, Park HS, Kim DY, Joh H, Oh J, Kim DH, Kang MJ, Choi CH, Kim HJ (2025) Siderophore-based targeted antibody recruitment for promoting immune responses towards Gram-negative pathogens. RSC Chem Biology 6(3):387\u2013393. https:\/\/doi.org\/10.1039\/d4cb00293h","journal-title":"RSC Chem Biology"},{"issue":"3","key":"4668_CR74","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10030373","volume":"10","author":"I Kyriakidis","year":"2021","unstructured":"Kyriakidis I, Vasileiou E, Pana ZD, Tragiannidis A (2021) Acinetobacter baumannii antibiotic resistance mechanisms. Pathogens 10(3):373. https:\/\/doi.org\/10.3390\/pathogens10030373","journal-title":"Pathogens"},{"issue":"2","key":"4668_CR75","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1093\/FEMSRE\/FUV049","volume":"40","author":"CKY Lau","year":"2016","unstructured":"Lau CKY, Krewulak KD, Vogel HJ (2016) Bacterial ferrous iron transport: the Feo system. FEMS Microbiol Rev 40(2):273\u2013298. https:\/\/doi.org\/10.1093\/FEMSRE\/FUV049","journal-title":"FEMS Microbiol Rev"},{"key":"4668_CR76","doi-asserted-by":"publisher","DOI":"10.1016\/J.MICRES.2022.127032","author":"SKK Law","year":"2022","unstructured":"Law SKK, Tan HS (2022) The role of quorum sensing, biofilm formation, and iron acquisition as key virulence mechanisms in Acinetobacter baumannii and the corresponding anti-virulence strategies. Microbiol Res. https:\/\/doi.org\/10.1016\/J.MICRES.2022.127032","journal-title":"Microbiol Res"},{"issue":"1","key":"4668_CR77","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1111\/J.1469-0691.2007.01842.X","volume":"14","author":"HW Lee","year":"2008","unstructured":"Lee HW, Koh YM, Kim J, Lee JC, Lee YC, Seol SY, Cho DT (2008) Capacity of multidrug-resistant clinical isolates of Acinetobacter baumannii to form biofilm and adhere to epithelial cell surfaces. Clin Microbiol Infect 14(1):49\u201354. https:\/\/doi.org\/10.1111\/J.1469-0691.2007.01842.X","journal-title":"Clin Microbiol Infect"},{"key":"4668_CR78","doi-asserted-by":"publisher","unstructured":"Lee Y, Kim CK, Lee H, Jeong SH, Yong D, Lee K (2011) A novel insertion sequence, ISAba10, inserted into ISAba1 adjacent to the bla\u2009OXA-23\u2009gene and disrupting the outer membrane protein gene CarO in Acinetobacter baumannii. Antimicrob Agents Chemother 55(1):361\u2013363. https:\/\/doi.org\/10.1128\/AAC.00938-10","DOI":"10.1128\/AAC.00938-10"},{"key":"4668_CR175","doi-asserted-by":"publisher","unstructured":"Lee YL, Ko WC,  Hsueh PR (2023) Geographic patterns of Acinetobacter baumannii and carbapenem resistance in the Asia-Pacific Region: results from the Antimicrobial Testing Leadership and Surveillance (ATLAS) program, 2012-2019. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 127:48\u201355. https:\/\/doi.org\/10.1016\/j.ijid.2022.12.010","DOI":"10.1016\/j.ijid.2022.12.010"},{"key":"4668_CR79","doi-asserted-by":"publisher","DOI":"10.3389\/FMICB.2019.02440\/FULL","volume":"10","author":"JM Lewis","year":"2019","unstructured":"Lewis JM, Lucas DD, Harper M, Boyce JD (2019) Systematic identification and analysis of Acinetobacter baumannii type vi secretion system effector and immunity components. Front Microbiol 10:2440. https:\/\/doi.org\/10.3389\/FMICB.2019.02440\/FULL","journal-title":"Front Microbiol"},{"key":"4668_CR80","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1186\/1471-2180-14-119","volume":"14","author":"MF Lin","year":"2014","unstructured":"Lin MF, Lin YY, Yeh HW, Lan CY (2014) Role of the BaeSR two-component system in the regulation of Acinetobacter baumannii AdeAB genes and its correlation with Tigecycline susceptibility. BMC Microbiol 14:119. https:\/\/doi.org\/10.1186\/1471-2180-14-119","journal-title":"BMC Microbiol"},{"issue":"1","key":"4668_CR81","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1007\/s44154-021-00008-z","volume":"1","author":"J Lin","year":"2021","unstructured":"Lin J, Xu L, Yang J, Wang Z, Shen X (2021) Beyond dueling: roles of the type VI secretion system in Microbiome modulation, pathogenesis and stress resistance. Stress Biol 1(1):11. https:\/\/doi.org\/10.1007\/s44154-021-00008-z","journal-title":"Stress Biol"},{"issue":"3","key":"4668_CR82","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/J.YGENO.2014.07.011","volume":"104","author":"CC Liu","year":"2014","unstructured":"Liu CC, Kuo HY, Tang CY, Chang KC, Liou ML (2014) Prevalence and mapping of a plasmid encoding a type IV secretion system in Acinetobacter baumannii. Genomics 104(3):215\u2013223. https:\/\/doi.org\/10.1016\/J.YGENO.2014.07.011","journal-title":"Genomics"},{"issue":"3","key":"4668_CR83","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1128\/JB.01416-07","volume":"190","author":"TW Loehfelm","year":"2008","unstructured":"Loehfelm TW, Luke NR, Campagnari AA (2008) Identification and characterization of an Acinetobacter baumannii biofilm-associated protein. J Bacteriol 190(3):1036\u20131044. https:\/\/doi.org\/10.1128\/JB.01416-07","journal-title":"J Bacteriol"},{"key":"4668_CR84","doi-asserted-by":"publisher","unstructured":"L\u00f3pez-Mart\u00edn M, Dubern JF, Alexander MR, Williams P (2021) AbaM regulates quorum sensing, biofilm formation, and virulence in Acinetobacter baumannii. J Bacteriol 203(8). https:\/\/doi.org\/10.1128\/JB.00635-20","DOI":"10.1128\/JB.00635-20"},{"issue":"1","key":"4668_CR85","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2023.2289769","volume":"15","author":"M Lucidi","year":"2024","unstructured":"Lucidi M, Visaggio D, Migliaccio A, Capecchi G, Visca P, Imperi F, Zarrilli R (2024) Pathogenicity and virulence of Acinetobacter baumannii: factors contributing to the fitness in healthcare settings and the infected host. Virulence 15(1):2289769. https:\/\/doi.org\/10.1080\/21505594.2023.2289769","journal-title":"Virulence"},{"key":"4668_CR86","doi-asserted-by":"publisher","unstructured":"Mack AR, Hujer AM, Mojica MF, Taracila MA, Feldgarden M, Haft DH, Klimke W, Prasad AB, Bonomo RA (2025) \u03b2-Lactamase diversity in Acinetobacter baumannii. Antimicrob Agents Chemother. https:\/\/doi.org\/10.1128\/AAC.00784-24\/SUPPL_FILE\/AAC.00784-24-S0003.XLSX","DOI":"10.1128\/AAC.00784-24\/SUPPL_FILE\/AAC.00784-24-S0003.XLSX"},{"key":"4668_CR87","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2013.00003","volume":"3","author":"N Maeshima","year":"2013","unstructured":"Maeshima N, Fernandez RC (2013) Recognition of lipid A variants by the TLR4-MD-2 receptor complex. Front Cell Infect Microbiol 3:3. https:\/\/doi.org\/10.3389\/fcimb.2013.00003","journal-title":"Front Cell Infect Microbiol"},{"issue":"12","key":"4668_CR88","doi-asserted-by":"publisher","first-page":"6101","DOI":"10.1093\/nar\/gkad341","volume":"51","author":"RP Maharjan","year":"2023","unstructured":"Maharjan RP, Sullivan GJ, Adams FG, Shah BS, Hawkey J, Delgado N, Semenec L, Dinh H, Li L, Short FL, Parkhill J, Paulsen IT, Barquist L, Eijkelkamp BA, Cain AK (2023) DksA is a conserved master regulator of stress response in Acinetobacter baumannii. Nucleic Acids Res 51(12):6101\u20136119. https:\/\/doi.org\/10.1093\/nar\/gkad341","journal-title":"Nucleic Acids Res"},{"issue":"6","key":"4668_CR89","doi-asserted-by":"publisher","first-page":"2752","DOI":"10.1016\/J.AJPATH.2011.02.007","volume":"178","author":"ML Manni","year":"2011","unstructured":"Manni ML, Tomai LP, Norris CA, Thomas LM, Kelley EE, Salter RD, Crapo JD, Chang LYL, Watkins SC, Piganelli JD, Oury TD (2011) Extracellular superoxide dismutase in macrophages augments bacterial killing by promoting phagocytosis. Am J Pathol 178(6):2752. https:\/\/doi.org\/10.1016\/J.AJPATH.2011.02.007","journal-title":"Am J Pathol"},{"key":"4668_CR90","doi-asserted-by":"publisher","first-page":"109","DOI":"10.3389\/fimmu.2013.00109","volume":"4","author":"M Matsuura","year":"2013","unstructured":"Matsuura M (2013) Structural modifications of bacterial lipopolysaccharide that facilitate Gram-negative bacteria evasion of host innate immunity. Front Immunol 4:109. https:\/\/doi.org\/10.3389\/fimmu.2013.00109","journal-title":"Front Immunol"},{"issue":"Pt 8","key":"4668_CR91","doi-asserted-by":"publisher","first-page":"2587","DOI":"10.1099\/mic.0.27141-0","volume":"150","author":"K Mihara","year":"2004","unstructured":"Mihara K, Tanabe T, Yamakawa Y, Funahashi T, Nakao H, Narimatsu S, Yamamoto S (2004) Identification and transcriptional organization of a gene cluster involved in biosynthesis and transport of acinetobactin, a siderophore produced by Acinetobacter baumannii ATCC 19606T. Microbiology 150(Pt 8):2587\u20132597. https:\/\/doi.org\/10.1099\/mic.0.27141-0","journal-title":"Microbiology"},{"issue":"1","key":"4668_CR92","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1146\/annurev-phyto-121423-084620","volume":"63","author":"J Mijatovi\u0107 Scouten","year":"2025","unstructured":"Mijatovi\u0107 Scouten J, Hsieh SC, Sung LK, Wen YV, Kuo CH, Lai EM, Chang JH (2025) Function, evolution, and ecology of type VI secretion systems of plant-associated bacteria. Annu Rev Phytopathol 63(1):333\u2013356. https:\/\/doi.org\/10.1146\/annurev-phyto-121423-084620","journal-title":"Annu Rev Phytopathol"},{"key":"4668_CR93","doi-asserted-by":"publisher","first-page":"728644","DOI":"10.3389\/fmicb.2021.728644","volume":"12","author":"S Mindlin","year":"2021","unstructured":"Mindlin S, Maslova O, Beletsky A, Nurmukanova V, Zong Z, Mardanov A, Petrova M (2021) Ubiquitous conjugative mega-plasmids of acinetobacter species and their role in horizontal transfer of multi-drug resistance. Front Microbiol 12:728644. https:\/\/doi.org\/10.3389\/fmicb.2021.728644","journal-title":"Front Microbiol"},{"issue":"12","key":"4668_CR94","doi-asserted-by":"publisher","first-page":"4971","DOI":"10.1128\/aac.00834-10","volume":"54","author":"JH Moffatt","year":"2010","unstructured":"Moffatt JH, Harper M, Harrison P, Hale JDF, Vinogradov E, Seemann T, Henry R, Crane B, Michael FS, Cox AD, Adler B, Nation RL, Li J, Boyce JD (2010) Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production. Antimicrob Agents Chemother 54(12):4971\u20134977. https:\/\/doi.org\/10.1128\/aac.00834-10","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"4668_CR95","doi-asserted-by":"publisher","DOI":"10.1186\/s43094-023-00525-w","volume":"9","author":"EA Mohamed","year":"2023","unstructured":"Mohamed EA, Raafat MM, Mohamed RS, Ali AEE (2023) Acinetobacter baumannii biofilm and its potential therapeutic targets. Future Journal of Pharmaceutical Sciences 9(1):82. https:\/\/doi.org\/10.1186\/s43094-023-00525-w","journal-title":"Future Journal of Pharmaceutical Sciences"},{"issue":"15","key":"4668_CR96","doi-asserted-by":"publisher","DOI":"10.3390\/IJMS21155498","volume":"21","author":"S Monem","year":"2020","unstructured":"Monem S, Furmanek-Blaszk B, \u0141upkowska A, Kuczy\u0144ska-Wi\u015bnik D, Stojowska-Sw\u0119drzy\u0144ska K, Laskowska E (2020) Mechanisms protecting Acinetobacter baumannii against multiple stresses triggered by the host immune response, antibiotics and outside-host environment. Int J Mol Sci 21(15):5498. https:\/\/doi.org\/10.3390\/IJMS21155498","journal-title":"Int J Mol Sci"},{"issue":"7","key":"4668_CR98","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1038\/nrmicro3047","volume":"11","author":"BD Needham","year":"2013","unstructured":"Needham BD, Trent MS (2013) Fortifying the barrier: the impact of lipid A remodelling on bacterial pathogenesis. Nat Rev Microbiol 11(7):467\u2013481. https:\/\/doi.org\/10.1038\/nrmicro3047","journal-title":"Nat Rev Microbiol"},{"issue":"6","key":"4668_CR99","doi-asserted-by":"publisher","first-page":"2715","DOI":"10.1111\/jam.15130","volume":"131","author":"SG Nguyen","year":"2021","unstructured":"Nguyen SG (2021) Carbapenem resistance in Acinetobacter baumannii, and their importance in hospital-acquired infections: a scientific review. J Appl Microbiol 131(6):2715\u20132738. https:\/\/doi.org\/10.1111\/jam.15130","journal-title":"J Appl Microbiol"},{"issue":"1","key":"4668_CR100","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/S12929-020-0617-7\/FIGURES\/1","volume":"27","author":"D Nie","year":"2020","unstructured":"Nie D, Hu Y, Chen Z, Li M, Hou Z, Luo X, Mao X, Xue X (2020) Outer membrane protein A (OmpA) as a potential therapeutic target for Acinetobacter baumannii infection. J Biomed Sci 27(1):1\u20138. https:\/\/doi.org\/10.1186\/S12929-020-0617-7\/FIGURES\/1","journal-title":"J Biomed Sci"},{"issue":"9","key":"4668_CR101","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01929-07","volume":"190","author":"C Niu","year":"2008","unstructured":"Niu C, Clemmer KM, Bonomo RA, Rather PN (2008) Isolation and characterization of an autoinducer synthase from Acinetobacter baumannii. J Bacteriol 190(9):3386. https:\/\/doi.org\/10.1128\/JB.01929-07","journal-title":"J Bacteriol"},{"issue":"1","key":"4668_CR102","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1111\/NYAS.14918","volume":"1518","author":"HR Noel","year":"2022","unstructured":"Noel HR, Petrey JR, Palmer LD (2022) Mobile genetic elements in acinetobacter antibiotic-resistance acquisition and dissemination. Ann N Y Acad Sci 1518(1):166\u2013182. https:\/\/doi.org\/10.1111\/NYAS.14918","journal-title":"Ann N Y Acad Sci"},{"issue":"12","key":"4668_CR103","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1016\/J.TIM.2011.09.005","volume":"19","author":"P Nordmann","year":"2011","unstructured":"Nordmann P, Poirel L, Walsh TR, Livermore DM (2011) The emerging NDM carbap enemases. Trends Microbiol 19(12):588\u2013595. https:\/\/doi.org\/10.1016\/J.TIM.2011.09.005","journal-title":"Trends Microbiol"},{"key":"4668_CR104","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2014.00643","author":"AO Olaitan","year":"2014","unstructured":"Olaitan AO, Morand S, Rolain J-M (2014) Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria. Front Microbiol. 5 https:\/\/doi.org\/10.3389\/fmicb.2014.00643","journal-title":"Front Microbiol"},{"issue":"46","key":"4668_CR105","doi-asserted-by":"publisher","first-page":"14150","DOI":"10.1021\/bi0012843","volume":"39","author":"L Otvos","year":"2000","unstructured":"Otvos L, Jr O, Rogers I, Consolvo ME, Condie PJ, Lovas BA, Bulet S, P., Blaszczyk-Thurin M (2000) Interaction between heat shock proteins and antimicrobial peptides. Biochemistry 39(46):14150\u201314159. https:\/\/doi.org\/10.1021\/bi0012843","journal-title":"Biochemistry"},{"issue":"4","key":"4668_CR106","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1016\/J.BJM.2016.06.005","volume":"47","author":"M Pagano","year":"2016","unstructured":"Pagano M, Martins AF, Barth AL (2016) Mobile genetic elements related to carbap enem resistance in Acinetobacter baumannii. Braz J Microbiol 47(4):785\u2013792. https:\/\/doi.org\/10.1016\/J.BJM.2016.06.005","journal-title":"Braz J Microbiol"},{"key":"4668_CR107","doi-asserted-by":"publisher","unstructured":"Palethorpe S, Farrow JM 3rd, Wells G, Milton ME, Actis LA, Cavanagh J, Pesci EC (2022) Acinetobacter baumannii regulates its stress responses via the BfmRS Two-Component regulatory system. J Bacteriol 204(2):e0049421. https:\/\/doi.org\/10.1128\/JB.00494-21","DOI":"10.1128\/JB.00494-21"},{"key":"4668_CR108","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-48441-8","author":"JH Park","year":"2024","unstructured":"Park JH, Mortaja M, Son HG, Zhao X, Sloat LM, Azin M, Wang J, Collier MR, Tummala KS, Mandinova A, Bardeesy N, Semenov YR, Mino-Kenudson M, Demehri S (2024) Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression. Nat Commun. https:\/\/doi.org\/10.1038\/s41467-024-48441-8","journal-title":"Nat Commun"},{"key":"4668_CR109","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00088-17","author":"SR Partridge","year":"2018","unstructured":"Partridge SR, Kwong SM, Firth N, Jensen SO (2018) Mobile genetic elements associated with antimicrobial resistance. Clin Microbiol Rev. https:\/\/doi.org\/10.1128\/CMR.00088-17","journal-title":"Clin Microbiol Rev"},{"issue":"5","key":"4668_CR110","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1111\/apm.13399","volume":"132","author":"NN Pathoor","year":"2024","unstructured":"Pathoor NN, Viswanathan A, Wadhwa G, Ganesh PS (2024) Understanding the biofilm development of Acinetobacter baumannii and novel strategies to combat infection. APMIS Acta Pathol Microbiol Immunol Scand 132(5):317\u2013335. https:\/\/doi.org\/10.1111\/apm.13399","journal-title":"APMIS Acta Pathol Microbiol Immunol Scand"},{"issue":"3","key":"4668_CR111","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1128\/CMR.00058-07","volume":"21","author":"AY Peleg","year":"2008","unstructured":"Peleg AY, Seifert H, Paterson DL (2008) Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev 21(3):538\u2013582. https:\/\/doi.org\/10.1128\/CMR.00058-07","journal-title":"Clin Microbiol Rev"},{"issue":"10","key":"4668_CR112","doi-asserted-by":"publisher","first-page":"4831","DOI":"10.1128\/AAC.00865-13\/SUPPL_FILE\/ZAC010132194SO1.PDF","volume":"57","author":"MR Pelletier","year":"2013","unstructured":"Pelletier MR, Casella LG, Jones JW, Adams MD, Zurawski DV, Hazlett KRO, Doi Y, Ernst RK (2013) Unique structural modifications are present in the lipopolysaccharide from colistin-resistant strains of Acinetobacter baumannii. Antimicrob Agents Chemother 57(10):4831\u20134840. https:\/\/doi.org\/10.1128\/AAC.00865-13\/SUPPL_FILE\/ZAC010132194SO1.PDF","journal-title":"Antimicrob Agents Chemother"},{"key":"4668_CR113","unstructured":"Penwell WF (2013) Iron acquisition in Acinetobacter baumannii (Doctoral dissertation, Miami University)"},{"issue":"28","key":"4668_CR114","doi-asserted-by":"publisher","first-page":"3740","DOI":"10.2174\/092986709789104957","volume":"16","author":"FJ P\u00e9rez-Llarena","year":"2009","unstructured":"P\u00e9rez-Llarena FJ, Bou G (2009) Beta-lactamase inhibitors: the story so far. Curr Med Chem 16(28):3740\u20133765. https:\/\/doi.org\/10.2174\/092986709789104957","journal-title":"Curr Med Chem"},{"key":"4668_CR115","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0175246","author":"N Piedra-Carrasco","year":"2017","unstructured":"Piedra-Carrasco N, F\u00e0brega A, Calero-C\u00e1ceres W, Cornejo-S\u00e1nchez T, Brown-Jaque M, Mir-Cros A, Muniesa M, Gonz\u00e1lez-L\u00f3pez JJ (2017) Carbapenemase-producing enterobacteriaceae recovered from a Spanish river ecosystem. PLoS One. https:\/\/doi.org\/10.1371\/journal.pone.0175246","journal-title":"PLoS One"},{"issue":"9","key":"4668_CR116","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1111\/J.1469-0691.2006.01456.X","volume":"12","author":"L Poirel","year":"2006","unstructured":"Poirel L, Nordmann P (2006) Carbapenem resistance in bap: mechanisms and epidemiology. Clin Microbiol Infect 12(9):826\u2013836. https:\/\/doi.org\/10.1111\/J.1469-0691.2006.01456.X","journal-title":"Clin Microbiol Infect"},{"key":"4668_CR186","doi-asserted-by":"publisher","unstructured":"Radusky LG, Hassan S, Lanzarotti E, Tiwari S, Jamal S, Ali J, Ali A, Ferreira R, Barh D, Silva A, Turjanski AG,  Azevedo VA (2015) An integrated structural proteomics approach along the druggable genome of Corynebacterium pseudotuberculosis species for putative druggable targets. BMC genomics, 16 Suppl 5(Suppl 5), S9. https:\/\/doi.org\/10.1186\/1471-2164-16-S5-S9","DOI":"10.1186\/1471-2164-16-S5-S9"},{"issue":"20","key":"4668_CR117","doi-asserted-by":"publisher","first-page":"3080","DOI":"10.15252\/EMBJ.201796629","volume":"36","author":"A Redzej","year":"2017","unstructured":"Redzej A, Ukleja M, Connery S, Trokter M, Felisberto-Rodrigues C, Cryar A, Thalassinos K, Hayward RD, Orlova EV, Waksman G (2017) Structure of a VirD4 coupling protein bound to a virb type IV secretion machinery. EMBO J 36(20):3080\u20133095. https:\/\/doi.org\/10.15252\/EMBJ.201796629","journal-title":"EMBO J"},{"issue":"9","key":"4668_CR118","doi-asserted-by":"publisher","first-page":"e0138265","DOI":"10.1371\/journal.pone.0138265","volume":"10","author":"GD Repizo","year":"2015","unstructured":"Repizo GD, Gagn\u00e9 S, Foucault-Grunenwald ML, Borges V, Charpentier X, Limansky AS, Gomes JP, Viale AM, Salcedo SP (2015) Differential role of the T6SS in Acinetobacter baumannii virulence. PLoS ONE 10(9):e0138265. https:\/\/doi.org\/10.1371\/journal.pone.0138265","journal-title":"PLoS ONE"},{"key":"4668_CR119","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.atherosclerosis.2015.11.015","volume":"244","author":"DM Rocha","year":"2016","unstructured":"Rocha DM, Caldas AP, Oliveira LL, Bressan J, Hermsdorff HH (2016) Saturated fatty acids trigger TLR4-mediated inflammatory response. Atherosclerosis 244:211\u2013215. https:\/\/doi.org\/10.1016\/j.atherosclerosis.2015.11.015","journal-title":"Atherosclerosis"},{"key":"4668_CR120","doi-asserted-by":"publisher","DOI":"10.3389\/FMICB.2024.1501051\/FULL","volume":"15","author":"M Romano","year":"2024","unstructured":"Romano M, Falchi F, Gregorio ED, Stabile M, Migliaccio A, Ruggiero A, Napolitano V, Autiero I, Squeglia F, Berisio R (2024) Structure-based targeting of the lipid A-modifying enzyme PmrC to contrast colistin resistance in Acinetobacter baumannii. Front Microbiol 15:1501051. https:\/\/doi.org\/10.3389\/FMICB.2024.1501051\/FULL","journal-title":"Front Microbiol"},{"issue":"1","key":"4668_CR121","doi-asserted-by":"publisher","DOI":"10.1074\/JBC.RA118.005814","volume":"294","author":"LA Ronish","year":"2018","unstructured":"Ronish LA, Lillehoj E, Fields JK, Sundberg EJ, Piepenbrink KH (2018) The structure of PilA from Acinetobacter baumannii AB5075 suggests a mechanism for functional specialization in Acinetobacter type IV pili. J Biol Chem 294(1):218. https:\/\/doi.org\/10.1074\/JBC.RA118.005814","journal-title":"J Biol Chem"},{"key":"4668_CR177","doi-asserted-by":"publisher","unstructured":"Rosenfeld Y,  Shai Y (2006) Lipopolysaccharide (Endotoxin)-host defense antibacterial peptides interactions: role in bacterial resistance and prevention of sepsis. Biochimica et biophysica acta, 1758(9):1513\u20131522. https:\/\/doi.org\/10.1016\/j.bbamem.2006.05.017","DOI":"10.1016\/j.bbamem.2006.05.017"},{"key":"4668_CR122","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.793615","author":"S Roy","year":"2022","unstructured":"Roy S, Chowdhury G, Mukhopadhyay AK, Dutta S, Basu S (2022) Convergence of biofilm formation and antibiotic resistance in Acinetobacter baumannii infection. Front Med (Lausanne). https:\/\/doi.org\/10.3389\/fmed.2022.793615","journal-title":"Front Med (Lausanne)"},{"issue":"7","key":"4668_CR123","doi-asserted-by":"publisher","first-page":"3084","DOI":"10.1128\/AAC.00929-10","volume":"55","author":"C Rumbo","year":"2011","unstructured":"Rumbo C, Fern\u00e1ndez-Moreira E, Merino M, Poza M, Mendez JA, Soares NC, Mosquera A, Chaves F, Bou G (2011) Horizontal transfer of the OXA-24 carbapenemase gene via outer membrane vesicles: a new mechanism of dissemination of carbapenem resistance genes in Acinetobacter baumannii. Antimicrob Agents Chemother 55(7):3084\u20133090. https:\/\/doi.org\/10.1128\/AAC.00929-10","journal-title":"Antimicrob Agents Chemother"},{"issue":"4","key":"4668_CR124","doi-asserted-by":"publisher","first-page":"e00755","DOI":"10.1128\/IAI.00755-18","volume":"87","author":"F Runci","year":"2019","unstructured":"Runci F, Gentile V, Frangipani E, Rampioni G, Leoni L, Lucidi M, Visaggio D, Harris G, Chen W, Stahl J, Averhoff B, Visca P (2019) Contribution of active iron uptake to Acinetobacter baumannii pathogenicity. Infect Immun 87(4):e00755\u2013e00718. https:\/\/doi.org\/10.1128\/IAI.00755-18","journal-title":"Infect Immun"},{"key":"4668_CR125","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1186\/1471-2164-12-291","volume":"12","author":"JW Sahl","year":"2011","unstructured":"Sahl JW, Johnson JK, Harris AD, Phillippy AM, Hsiao WW, Thom KA, Rasko DA (2011) Genomic comparison of multi-drug resistant invasive and colonizing Acinetobacter baumannii isolated from diverse human body sites reveals genomic plasticity. BMC Genomics 12:291. https:\/\/doi.org\/10.1186\/1471-2164-12-291","journal-title":"BMC Genomics"},{"issue":"1","key":"4668_CR126","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1111\/jam.14330","volume":"128","author":"K Saipriya","year":"2020","unstructured":"Saipriya K, Swathi CH, Ratnakar KS, Sritharan V (2020) Quorum-sensing system in Acinetobacter baumannii: a potential target for new drug development. J Appl Microbiol 128(1):15\u201327. https:\/\/doi.org\/10.1111\/jam.14330","journal-title":"J Appl Microbiol"},{"issue":"1","key":"4668_CR127","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/S12879-025-11185-X","volume":"25","author":"S Salem","year":"2025","unstructured":"Salem S, Osama D, Abdelsalam NA, Shata AH, Mouftah SF, Elhadidy M (2025) Comparative genomics of Acinetobacter baumannii from Egyptian healthcare settings reveals high-risk clones and resistance gene mobilization. BMC Infect Dis 25(1):1\u201314. https:\/\/doi.org\/10.1186\/S12879-025-11185-X","journal-title":"BMC Infect Dis"},{"key":"4668_CR179","doi-asserted-by":"publisher","unstructured":"Salgado-Camargo AD, Castro-Jaimes S, Gutierrez-Rios RM, Lozano LF, Altamirano-Pacheco L, Silva-Sanchez J, P\u00e9rez-Oseguera \u00c1, Volkow P, Castillo-Ram\u00edrez S,  Cevallos MA (2020) Structure and Evolution of Acinetobacter baumannii Plasmids. Frontiers microbiol 11:1283. https:\/\/doi.org\/10.3389\/fmicb.2020.01283","DOI":"10.3389\/fmicb.2020.01283"},{"issue":"1","key":"4668_CR128","doi-asserted-by":"publisher","first-page":"17462","DOI":"10.1038\/s41598-019-53846-3","volume":"9","author":"Y Sato","year":"2019","unstructured":"Sato Y, Unno Y, Miyazaki C, Ubagai T, Ono Y (2019) Multidrug-resistant Acinetobacter baumannii resists reactive oxygen species and survives in macrophages. Sci Rep 9(1):17462. https:\/\/doi.org\/10.1038\/s41598-019-53846-3","journal-title":"Sci Rep"},{"issue":"5","key":"4668_CR129","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1615\/CritRevImmunol.v20.i5.40","volume":"20","author":"MG Scott","year":"2000","unstructured":"Scott MG, Hancock RE (2000) Cationic antimicrobial peptides and their multifunctional role in the immune system. Crit Rev Immunol 20(5):407\u2013431","journal-title":"Crit Rev Immunol"},{"key":"4668_CR130","unstructured":"Secretion Systems of Acinetobacter baumannii | Encyclopedia MDPI. (n.d.). https:\/\/encyclopedia.pub\/entry\/40727"},{"key":"4668_CR184","doi-asserted-by":"publisher","unstructured":"Seputiene V, Povilonis J,  Suziedeliene E (2012) Novel variants of AbaR resistance islands with a common backbone in Acinetobacter baumannii isolates of European clone II. Antimicrob agents chemother 56(4):1969\u20131973. https:\/\/doi.org\/10.1128\/AAC.05678-11","DOI":"10.1128\/AAC.05678-11"},{"issue":"10","key":"4668_CR131","doi-asserted-by":"publisher","first-page":"e1008995","DOI":"10.1371\/journal.ppat.1008995","volume":"16","author":"JR Sheldon","year":"2020","unstructured":"Sheldon JR, Skaar EP (2020) Acinetobacter baumannii can use multiple siderophores for iron acquisition, but only acinetobactin is required for virulence. PLoS Pathog 16(10):e1008995. https:\/\/doi.org\/10.1371\/journal.ppat.1008995","journal-title":"PLoS Pathog"},{"key":"4668_CR132","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.716627","author":"MM Sherif","year":"2021","unstructured":"Sherif MM, Elkhatib WF, Khalaf WS, Elleboudy NS, Abdelaziz NA (2021) Multidrug resistant Acinetobacter baumannii biofilms: evaluation of phenotypic\u2013genotypic association and susceptibility to cinnamic and gallic acids. Front Microbiol. https:\/\/doi.org\/10.3389\/fmicb.2021.716627","journal-title":"Front Microbiol"},{"key":"4668_CR133","doi-asserted-by":"publisher","first-page":"1332108","DOI":"10.3389\/fmicb.2024.1332108","volume":"15","author":"J Shi","year":"2024","unstructured":"Shi J, Cheng J, Liu S, Zhu Y, Zhu M (2024) Acinetobacter baumannii: an evolving and cunning opponent. Front Microbiol 15:1332108. https:\/\/doi.org\/10.3389\/fmicb.2024.1332108","journal-title":"Front Microbiol"},{"issue":"3","key":"4668_CR134","doi-asserted-by":"publisher","first-page":"29","DOI":"10.3390\/MICROORGANISMS4030029","volume":"4","author":"GJD Silva","year":"2016","unstructured":"Silva GJD, Domingues S (2016) Insights on the horizontal gene transfer of Carbapenemase determinants in the opportunistic pathogen Acinetobacter baumannii. Microorganisms 4(3):29. https:\/\/doi.org\/10.3390\/MICROORGANISMS4030029","journal-title":"Microorganisms"},{"issue":"11","key":"4668_CR135","doi-asserted-by":"publisher","first-page":"2602","DOI":"10.7860\/JCDR\/2013\/6337.3626","volume":"7","author":"H Singh","year":"2013","unstructured":"Singh H, Thangaraj P, Chakrabarti A (2013) Acinetobacter baumannii: a brief account of mechanisms of multidrug resistance and current and future therapeutic management. Journal of Clinical and Diagnostic Research: JCDR 7(11):2602. https:\/\/doi.org\/10.7860\/JCDR\/2013\/6337.3626","journal-title":"Journal of Clinical and Diagnostic Research: JCDR"},{"key":"4668_CR136","doi-asserted-by":"publisher","first-page":"3301","DOI":"10.3389\/fmicb.2018.03301","volume":"9","author":"JK Singh","year":"2019","unstructured":"Singh JK, Adams FG, Brown MH (2019) Diversity and function of capsular polysaccharide in Acinetobacter baumannii. Front Microbiol 9:3301. https:\/\/doi.org\/10.3389\/fmicb.2018.03301","journal-title":"Front Microbiol"},{"issue":"3","key":"4668_CR137","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.ijmm.2012.03.003","volume":"302","author":"E Skiebe","year":"2012","unstructured":"Skiebe E, de Berardinis V, Morczinek P, Kerrinnes T, Faber F, Lepka D, Hammer B, Zimmermann O, Ziesing S, Wichelhaus TA, Hunfeld KP, Borgmann S, Gr\u00f6bner S, Higgins PG, Seifert H, Busse HJ, Witte W, Pfeifer Y, Wilharm G (2012) Surface-associated motility, a common trait of clinical isolates of Acinetobacter baumannii, depends on 1,3-diaminopropane. Int J Med Microbiol 302(3):117\u2013128. https:\/\/doi.org\/10.1016\/j.ijmm.2012.03.003","journal-title":"Int J Med Microbiol"},{"issue":"3","key":"4668_CR138","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1111\/J.1365-2958.2011.07612.X","volume":"80","author":"JM Slauch","year":"2011","unstructured":"Slauch JM (2011) How does the oxidative burst of macrophages kill bacteria? Still an open question. Mol Microbiol 80(3):580. https:\/\/doi.org\/10.1111\/J.1365-2958.2011.07612.X","journal-title":"Mol Microbiol"},{"issue":"10","key":"4668_CR139","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1093\/infdis\/jit386","volume":"208","author":"Y Smani","year":"2013","unstructured":"Smani Y, Dominguez-Herrera J, Pachon J (2013) Association of the outer membrane protein Omp33 with fitness and virulence of Acinetobacter baumannii. J Infect Dis 208(10):1561\u20131570. https:\/\/doi.org\/10.1093\/infdis\/jit386","journal-title":"J Infect Dis"},{"key":"4668_CR140","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.micpath.2017.06.015","volume":"110","author":"C Staerck","year":"2017","unstructured":"Staerck C, Gastebois A, Vandeputte P, Calenda A, Larcher G, Gillmann L, Papon N, Bouchara JP, Fleury MJJ (2017) Microbial antioxidant defense enzymes. Microb Pathog 110:56\u201365. https:\/\/doi.org\/10.1016\/j.micpath.2017.06.015","journal-title":"Microb Pathog"},{"issue":"1","key":"4668_CR141","doi-asserted-by":"publisher","first-page":"4321","DOI":"10.1038\/s41598-022-08052-z","volume":"12","author":"BA Steimbr\u00fcch","year":"2022","unstructured":"Steimbr\u00fcch BA, Sartorio MG, Cortez N, Albanesi D, Lisa MN, Repizo GD (2022) The distinctive roles played by the superoxide dismutases of the extremophile acinetobacter sp. Ver3. Sci Rep 12(1):4321. https:\/\/doi.org\/10.1038\/s41598-022-08052-z","journal-title":"Sci Rep"},{"key":"4668_CR143","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/167572","volume":"2015","author":"Y Sun","year":"2015","unstructured":"Sun Y, Shang D (2015) Inhibitory effects of antimicrobial peptides on lipopolysaccharide-induced inflammation. Mediators Inflamm 2015:167572. https:\/\/doi.org\/10.1155\/2015\/167572","journal-title":"Mediators Inflamm"},{"key":"4668_CR144","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/J.LFS.2016.02.015","volume":"148","author":"D Sun","year":"2016","unstructured":"Sun D, Crowell SA, Harding CM, Silva PMD, Harrison A, Fernando DM, Mason KM, Santana E, Loewen PC, Kumar A, Liu Y (2016) KatG and KatE confer acinetobacter resistance to hydrogen peroxide but sensitize bacteria to killing by phagocytic respiratory burst. Life Sci 148:31\u201340. https:\/\/doi.org\/10.1016\/J.LFS.2016.02.015","journal-title":"Life Sci"},{"issue":"23","key":"4668_CR145","doi-asserted-by":"publisher","first-page":"8044","DOI":"10.1128\/JB.00824-06","volume":"188","author":"MF Susin","year":"2006","unstructured":"Susin MF, Baldini RL, Gueiros-Filho F, Gomes SL (2006) GroES\/GroEL and DnaK\/DnaJ have distinct roles in stress responses and during cell cycle progression in caulobacter crescentus. J Bacteriol 188(23):8044. https:\/\/doi.org\/10.1128\/JB.00824-06","journal-title":"J Bacteriol"},{"issue":"10","key":"4668_CR146","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1038\/EMBOJ.2008.77","volume":"27","author":"YC Tang","year":"2008","unstructured":"Tang YC, Chang HC, Chakraborty K, Hartl FU, Hayer-Hartl M (2008) Essential role of the chaperonin folding compartment in vivo. EMBO J 27(10):1458. https:\/\/doi.org\/10.1038\/EMBOJ.2008.77","journal-title":"EMBO J"},{"key":"4668_CR176","doi-asserted-by":"publisher","unstructured":"Taylor CM,  Roberts IS (2005) Capsular polysaccharides and their role in virulence. Contribu microbiol 12:55\u201366. https:\/\/doi.org\/10.1159\/000081689","DOI":"10.1159\/000081689"},{"issue":"12","key":"4668_CR147","doi-asserted-by":"publisher","first-page":"111367","DOI":"10.1016\/j.isci.2024.111367","volume":"27","author":"A Thacharodi","year":"2024","unstructured":"Thacharodi A, Vithlani A, Hassan S, Alqahtani A, Pugazhendhi A (2024) Carbapenem-resistant Acinetobacter baumannii raises global alarm for new antibiotic regimens. iScience 27(12):111367. https:\/\/doi.org\/10.1016\/j.isci.2024.111367","journal-title":"iScience"},{"issue":"9","key":"4668_CR148","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1038\/NRMICRO1234","volume":"3","author":"CM Thomas","year":"2005","unstructured":"Thomas CM, Nielsen KM (2005) Mechanisms of, and barriers to, horizontal gene transfer between bacteria. Nat Rev Microbiol 3(9):711\u2013721. https:\/\/doi.org\/10.1038\/NRMICRO1234","journal-title":"Nat Rev Microbiol"},{"issue":"1","key":"4668_CR149","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-020-79966-9","volume":"11","author":"V Tiku","year":"2021","unstructured":"Tiku V, Kofoed EM, Yan D, Kang J, Xu M, Reichelt M, Dikic I, Tan MW (2021) Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii. Sci Rep 11(1):1\u201316. https:\/\/doi.org\/10.1038\/s41598-020-79966-9","journal-title":"Sci Rep"},{"issue":"15","key":"4668_CR150","doi-asserted-by":"publisher","first-page":"2593","DOI":"10.1128\/JB.00188-15","volume":"197","author":"KA Tipton","year":"2015","unstructured":"Tipton KA, Dimitrova D, Rather PN (2015) Phase-variable control of multiple phenotypes in Acinetobacter baumannii strain AB5075. J Bacteriol 197(15):2593. https:\/\/doi.org\/10.1128\/JB.00188-15","journal-title":"J Bacteriol"},{"issue":"12","key":"4668_CR151","doi-asserted-by":"publisher","first-page":"3473","DOI":"10.1099\/MIC.0.26541-0","volume":"149","author":"AP Tomaras","year":"2003","unstructured":"Tomaras AP, Dorsey CW, Edelmann RE, Actis LA (2003) Attachment to and biofilm formation on abiotic surfaces by Acinetobacter baumannii: involvement of a novel chaperone-usher pili assembly system. Microbiology 149(12):3473\u20133484. https:\/\/doi.org\/10.1099\/MIC.0.26541-0","journal-title":"Microbiology"},{"issue":"10","key":"4668_CR152","doi-asserted-by":"publisher","first-page":"2866","DOI":"10.1093\/gbe\/evu225","volume":"6","author":"M Touchon","year":"2014","unstructured":"Touchon M, Cury J, Yoon EJ, Krizova L, Cerqueira GC, Murphy C, Feldgarden M, Wortman J, Clermont D, Lambert T, Grillot-Courvalin C, Nemec A, Courvalin P, Rocha EP (2014) The genomic diversification of the whole acinetobacter genus: origins, mechanisms, and consequences. Genome Biol Evol 6(10):2866\u20132882. https:\/\/doi.org\/10.1093\/gbe\/evu225","journal-title":"Genome Biol Evol"},{"key":"4668_CR153","doi-asserted-by":"publisher","DOI":"10.1016\/j.crmicr.2022.100131","volume":"3","author":"K Upmanyu","year":"2022","unstructured":"Upmanyu K, Haq QMR, Singh R (2022) Factors mediating Acinetobacter baumannii biofilm formation: opportunities for developing therapeutics. Curr Res Microb Sci 3:100131. https:\/\/doi.org\/10.1016\/j.crmicr.2022.100131","journal-title":"Curr Res Microb Sci"},{"key":"4668_CR154","doi-asserted-by":"publisher","DOI":"10.3389\/FMICB.2022.869653\/BIBTEX","volume":"13","author":"S Vijayakumar","year":"2022","unstructured":"Vijayakumar S, Jacob JJ, Vasudevan K, Mathur P, Ray P, Neeravi A, Baskaran A, Kirubananthan A, Anandan S, Biswas I, Walia K, Veeraraghavan B (2022) Genomic characterization of mobile genetic elements associated with carbap enem resistance of Acinetobacter baumannii from India. Front Microbiol 13:869653. https:\/\/doi.org\/10.3389\/FMICB.2022.869653\/BIBTEX","journal-title":"Front Microbiol"},{"issue":"6","key":"4668_CR155","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.1093\/JAC\/DKL509","volume":"59","author":"J Vila","year":"2007","unstructured":"Vila J, Mart\u00ed S, S\u00e1nchez-C\u00e9spedes J (2007) Porins, efflux pumps and multidrug resistance in Acinetobacter baumannii. J Antimicrob Chemother 59(6):1210\u20131215. https:\/\/doi.org\/10.1093\/JAC\/DKL509","journal-title":"J Antimicrob Chemother"},{"key":"4668_CR156","doi-asserted-by":"publisher","unstructured":"Vrancianu CO, Pelcaru CF, Alistar A, Gheorghe I, Marutescu L, Popa M, Czobor I, Gradisteanu G, Dobre EG, Chifiriuc MC (2021) Escaping from ESKAPE. Clinical significance and antibiotic resistance mechanisms in Acinetobacter baumannii: a review.\u00a0Biointerface Res Appl Chem. 11(1):8190\u20138203. https:\/\/doi.org\/10.33263\/BRIAC111.81908203","DOI":"10.33263\/BRIAC111.81908203"},{"issue":"8","key":"4668_CR157","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00334-19","volume":"63","author":"JI Wachino","year":"2019","unstructured":"Wachino JI, Jin W, Kimura K, Arakawa Y (2019) Intercellular transfer of chromosomal antimicrobial resistance genes between Acinetobacter baumannii strains mediated by prophages. Antimicrob Agents Chemother 63(8):e00334-19. https:\/\/doi.org\/10.1128\/AAC.00334-19","journal-title":"Antimicrob Agents Chemother"},{"key":"4668_CR158","unstructured":"Wan Mohd Noor WSA, A Shukor NS, Mohd Sukri MA (2024) Acinetobacter baumannii: a current review of virulence factors and their clinical significance. J Microb Biol. 13(52):35\u201353"},{"issue":"10","key":"4668_CR159","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10101196","volume":"10","author":"Z Wang","year":"2021","unstructured":"Wang Z, Li H, Zhang J, Wang H (2021) Co-occurrence of bla<Subscript>OXA-23<\/Subscript> in the chromosome and plasmid: increased fitness in carbapenem-resistant Acinetobacter baumannii. Antibiotics 10(10):1196. https:\/\/doi.org\/10.3390\/antibiotics10101196","journal-title":"Antibiotics"},{"key":"4668_CR160","doi-asserted-by":"publisher","DOI":"10.1016\/j.micres.2025.128105","volume":"295","author":"H Wang","year":"2025","unstructured":"Wang H, Xu Q, Zhao W, Chan BKW, Chen K, Xie M, Yang X, Ni H, Chan EWC, Yang G, Chen S (2025) Simultaneous functional disruption of the iron acquisition system and type VI secretion system results in complete suppression of virulence in Acinetobacter baumannii. Microbiol Res 295:128105. https:\/\/doi.org\/10.1016\/j.micres.2025.128105","journal-title":"Microbiol Res"},{"key":"4668_CR161","doi-asserted-by":"publisher","unstructured":"Weber BS, Hennon SW, Wright MS, Scott NE, de Berardinis V, Foster LJ, Ayala JA, Adams MD, Feldman MF (2016) Genetic dissection of the type VI secretion system in acinetobacter and identification of a novel peptidoglycan hydrolase, TagX, required for its biogenesis. mBio. https:\/\/doi.org\/10.1128\/MBIO.01253-16\/SUPPL_FILE\/MBO005163027ST2.DOCX","DOI":"10.1128\/MBIO.01253-16\/SUPPL_FILE\/MBO005163027ST2.DOCX"},{"issue":"12","key":"4668_CR162","doi-asserted-by":"publisher","first-page":"e00454","DOI":"10.1128\/IAI.00454-21","volume":"89","author":"CDM Wijers","year":"2021","unstructured":"Wijers CDM, Pham L, Menon S, Boyd KL, Noel HR, Skaar EP, Gaddy JA, Palmer LD, Noto MJ (2021) Identification of two variants of Acinetobacter baumannii strain ATCC 17978 with distinct genotypes and phenotypes. Infect Immun 89(12):e00454\u2013e00421. https:\/\/doi.org\/10.1128\/IAI.00454-21","journal-title":"Infect Immun"},{"key":"4668_CR163","doi-asserted-by":"publisher","DOI":"10.1038\/S44259-024-00074-Z","author":"RL Wimalasekara","year":"2025","unstructured":"Wimalasekara RL, White D, Kumar A (2025) Targeting Acinetobacter baumannii resistance-nodulation-division efflux pump transcriptional regulators to combat antimicrobial resistance. NPJ Antimicrob Resist. https:\/\/doi.org\/10.1038\/S44259-024-00074-Z","journal-title":"NPJ Antimicrob Resist"},{"key":"4668_CR185","doi-asserted-by":"publisher","unstructured":"Wisal A, Saeed N, Aurongzeb M, Shafique M, Sohail S, Anwar W, Basharat Z, Irfan M, Ullah A,  Hassan SS (2024) Bridging drug discovery through hierarchical subtractive genomics against asd, trpG, and secY of pneumonia-causing MDR Staphylococcus aureus. Mol Genet Genomics, 299(1):34. https:\/\/doi.org\/10.1007\/s00438-024-02115-8","DOI":"10.1007\/s00438-024-02115-8"},{"issue":"1","key":"4668_CR164","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1128\/CMR.00058-16","volume":"30","author":"D Wong","year":"2016","unstructured":"Wong D, Nielsen TB, Bonomo RA, Pantapalangkoor P, Luna B, Spellberg B (2016) Clinical and pathophysiological overview of acinetobacter infections: a century of challenges. Clin Microbiol Rev 30(1):409. https:\/\/doi.org\/10.1128\/CMR.00058-16","journal-title":"Clin Microbiol Rev"},{"key":"4668_CR173","unstructured":"World Health Organization (2024) WHO bacterial priority pathogens list (BPPL) 2024: bacterial pathogens of public health importance to guide research, development and strategies to prevent and control antimicrobial resistance. Geneva: World Health Organization. Available from: https:\/\/www.who.int\/publications\/i\/item\/9789240093461"},{"issue":"7","key":"4668_CR165","doi-asserted-by":"publisher","DOI":"10.1128\/aac.01858-24","volume":"69","author":"L Xie","year":"2025","unstructured":"Xie L, Li J, Peng Q, Liu X, Lin F, Dai X, Ling B (2025) Contribution of RND superfamily multidrug efflux pumps AdeABC, AdeFGH, and AdeIJK to antimicrobial resistance and virulence factors in multidrug-resistant Acinetobacter baumannii AYE. Antimicrob Agents Chemother 69(7):e0185824. https:\/\/doi.org\/10.1128\/aac.01858-24","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"4668_CR166","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/S12866-022-02612-Z\/TABLES\/3","volume":"22","author":"L Xiong","year":"2022","unstructured":"Xiong L, Yi F, Yu Q, Huang X, Ao K, Wang Y, Xie Y (2022) Transcriptomic analysis reveals the regulatory role of quorum sensing in the Acinetobacter baumannii ATCC 19606 via RNA-seq. BMC Microbiol 22(1):1\u201312. https:\/\/doi.org\/10.1186\/S12866-022-02612-Z\/TABLES\/3","journal-title":"BMC Microbiol"},{"issue":"2","key":"4668_CR167","doi-asserted-by":"publisher","DOI":"10.3390\/ANTIBIOTICS13020149\/S1","volume":"13","author":"T Yaikhan","year":"2024","unstructured":"Yaikhan T, Chukamnerd A, Singkhamanan K, Nokchan N, Chintakovid N, Chusri S, Pomwised R, Wonglapsuwan M, Surachat K (2024) Genomic characterization of mobile genetic elements associated with multidrug-resistant Acinetobacter non-baumannii species from southern Thailand. Antibiotics 13(2):149. https:\/\/doi.org\/10.3390\/ANTIBIOTICS13020149\/S1","journal-title":"Antibiotics"},{"issue":"10","key":"4668_CR168","doi-asserted-by":"publisher","first-page":"2923","DOI":"10.1021\/acschembio.2c00573","volume":"17","author":"J Yang","year":"2022","unstructured":"Yang J, Wencewicz TA (2022) In vitro reconstitution of Fimsbactin biosynthesis from Acinetobacter baumannii. ACS Chem Biol 17(10):2923\u20132935. https:\/\/doi.org\/10.1021\/acschembio.2c00573","journal-title":"ACS Chem Biol"},{"key":"4668_CR169","doi-asserted-by":"publisher","first-page":"1565965","DOI":"10.3389\/fmicb.2025.1565965","volume":"16","author":"A Yehya","year":"2025","unstructured":"Yehya A, Ezzeddine Z, Chakkour M, Dhaini Z, Bou Saba MS, Saba B, Nohra AS, Nassar L, Yassine NB, Bahmad M, Ghssein G (2025) The intricacies of Acinetobacter baumannii: a multifaceted comprehensive review of a multidrug-resistant pathogen and its clinical significance and implications. Front Microbiol 16:1565965. https:\/\/doi.org\/10.3389\/fmicb.2025.1565965","journal-title":"Front Microbiol"},{"issue":"16","key":"4668_CR170","doi-asserted-by":"publisher","first-page":"5200","DOI":"10.1021\/JA068922A","volume":"129","author":"Y Zhang","year":"2007","unstructured":"Zhang Y, Gaekwad J, Wolfert MA, Boons GJ (2007) Modulation of innate immune responses with synthetic lipid A derivatives. J Am Chem Soc 129(16):5200. https:\/\/doi.org\/10.1021\/JA068922A","journal-title":"J Am Chem Soc"},{"key":"4668_CR171","doi-asserted-by":"publisher","DOI":"10.1093\/jacamr\/dlaf039","author":"R Zhang","year":"2025","unstructured":"Zhang R, Li D, Fang H, Xie Q, Tang H, Chen L (2025) Iron-dependent mechanisms in Acinetobacter baumannii: pathogenicity and resistance. JAC Antimicrob Resist. https:\/\/doi.org\/10.1093\/jacamr\/dlaf039","journal-title":"JAC Antimicrob Resist"},{"key":"4668_CR172","doi-asserted-by":"publisher","unstructured":"Zhu Y, Lu J, Han M-L, Jiang X, Azad MAK, Patil NA, Lin Y-W, Zhao J, Hu Y, Yu HH, Chen K, Boyce JD, Dunstan RA, Lithgow T, Barlow CK, Li W, Schneider-Futschik EK, Wang J, Gong B, Li J (2020) Polymyxins bind to the cell surface of unculturable Acinetobacter baumannii and cause unique dependent resistance. Adv Sci. https:\/\/doi.org\/10.1002\/advs.202000704","DOI":"10.1002\/advs.202000704"}],"container-title":["Archives of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00203-025-04668-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00203-025-04668-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00203-025-04668-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T11:59:39Z","timestamp":1774699179000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00203-025-04668-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,2]]},"references-count":182,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["4668"],"URL":"https:\/\/doi.org\/10.1007\/s00203-025-04668-7","relation":{},"ISSN":["0302-8933","1432-072X"],"issn-type":[{"value":"0302-8933","type":"print"},{"value":"1432-072X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,2]]},"assertion":[{"value":"8 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 December 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 December 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 February 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"162"}}