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Therefore, this study aimed to assess whether\n                    <jats:italic>K. pneumoniae<\/jats:italic>\n                    from CA infections share microbiological and molecular features with isolates recovered from an urban river in Salvador, Brazil. A total of 115 isolates, including 65 from CA infections and 50 from river water, were analyzed using antimicrobial susceptibility testing, \u03b2-lactamase and virulence gene detection, and multilocus sequence typing (MLST). Resistance rates were similar between groups, including multidrug resistance (24.6% vs. 22.0%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&gt;\u20090.05) and carbapenem resistance (4.6% vs. 4.0%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&gt;\u20090.05). \u03b2-lactamase gene detection was consistent with observed resistance patterns, with\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>CTX\u2212M<\/jats:sub>\n                    detected in 18.5% of CA isolates and 12.0% of river isolates, while\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>KPC\u22122<\/jats:sub>\n                    (3.1% vs. 2.0%) and\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>NDM\u22121<\/jats:sub>\n                    (1.5% vs. 2.0%) occurred at comparable frequencies. However, hypervirulent\n                    <jats:italic>K. pneumoniae<\/jats:italic>\n                    isolates were identified only among CA infections (4.6%). MLST revealed high clonal diversity, with 88 sequence types (STs), including 14 novel STs, with most STs being singletons. Four STs were shared between groups, including the high-risk lineages ST11 and ST307. These findings indicate that clinically relevant\n                    <jats:italic>K. pneumoniae<\/jats:italic>\n                    lineages, including high-risk, occur beyond healthcare settings, with urban aquatic environments serving as potential environmental reservoirs.\n                  <\/jats:p>","DOI":"10.1007\/s00203-026-05239-0","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:26:09Z","timestamp":1791257169000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Klebsiella pneumoniae from community-acquired infections and an urban river share antimicrobial resistance profiles and high-risk lineages but differ in virulence"],"prefix":"10.1007","volume":"208","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6675-4217","authenticated-orcid":false,"given":"Adriano Souza Santos","family":"Monteiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3553-9690","authenticated-orcid":false,"given":"Jo\u00e3o Ricardo","family":"Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6796-0610","authenticated-orcid":false,"given":"V\u00edvian Santos","family":"Galv\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7493-2009","authenticated-orcid":false,"given":"Vanessa Tibolla","family":"Moretto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8703-8498","authenticated-orcid":false,"given":"Ana Beatriz","family":"Purifica\u00e7\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8034-6532","authenticated-orcid":false,"given":"Lee Senhorinha Almeida","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1016-041X","authenticated-orcid":false,"given":"Camila Maria Pi\u00f1eiro","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7272-0515","authenticated-orcid":false,"given":"L\u00facio Macedo","family":"Barbosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7739-4082","authenticated-orcid":false,"given":"Luciano Kalabric","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5320-892X","authenticated-orcid":false,"given":"Soraia Machado","family":"Cordeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6655-7336","authenticated-orcid":false,"given":"Ronald Edward","family":"Blanton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5273-2658","authenticated-orcid":false,"given":"Joice Neves","family":"Reis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3051-9060","authenticated-orcid":false,"given":"Mitermayer Galv\u00e3o","family":"Reis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,6]]},"reference":[{"key":"5239_CR1","doi-asserted-by":"publisher","first-page":"4380","DOI":"10.1128\/AAC.02753-15","volume":"60","author":"CFM Araujo","year":"2016","unstructured":"Araujo CFM, Silva DM, Carneiro MT, Ribeiro S, Fontana-Maurell M, Alvarez P et al (2016) Detection of carbapenemase genes in aquatic environments in Rio de Janeiro, Brazil. 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