{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T13:55:14Z","timestamp":1768830914397,"version":"3.49.0"},"reference-count":68,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2007,11,30]],"date-time":"2007-11-30T00:00:00Z","timestamp":1196380800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Toxicol"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1007\/s00204-007-0255-9","type":"journal-article","created":{"date-parts":[[2007,11,29]],"date-time":"2007-11-29T07:35:20Z","timestamp":1196321720000},"page":"343-353","source":"Crossref","is-referenced-by-count":16,"title":["Attenuation by methyl mercury and mercuric sulfide of pentobarbital induced hypnotic tolerance in mice through inhibition of ATPase activities and nitric oxide production in cerebral cortex"],"prefix":"10.1007","volume":"82","author":[{"given":"Jiunn-Jye","family":"Chuu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zih-Ning","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsun-Hsin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang-Hao","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoei-Yn","family":"Lin-Shiau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,11,30]]},"reference":[{"issue":"1","key":"255_CR1","first-page":"67","volume":"85","author":"AN Alexidis","year":"1994","unstructured":"Alexidis AN, Rekka EA, Kourounakis PN (1994) Influence of mercury and cadmium intoxication on hepatic microsomal CYP2E and CYP3A subfamilies. Res Commun Mol Pathol Pharmacol 85(1):67\u201372","journal-title":"Res Commun Mol Pathol Pharmacol"},{"issue":"2","key":"255_CR2","first-page":"125","volume":"13","author":"F Anjum","year":"1994","unstructured":"Anjum F, Shakoori AR (1994) Sublethal effects of inorganic mercury on the bodygrowth rate and liver function enzymes of phenobarbitone-pretreated and promethazine-pretreated rabbits. J Environ Pathol Toxicol Oncol 13(2):125\u2013132","journal-title":"J Environ Pathol Toxicol Oncol"},{"issue":"1\u20132","key":"255_CR3","first-page":"61","volume":"185","author":"Z Annau","year":"1987","unstructured":"Annau Z (1987) The use of pharmacological challenges in behavioral toxicology. Zentralbl Bakteriol Mikrobiol Hyg B 185(1\u20132):61\u201364","journal-title":"Zentralbl Bakteriol Mikrobiol Hyg B"},{"issue":"2","key":"255_CR4","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/tera.1420380207","volume":"38","author":"M Aschner","year":"1988","unstructured":"Aschner M, Clarkson TW (1988) Distribution of mercury 203 in pregnant rats and their fetuses following systemic infusions with thiol-containing amino acids and glutathione during late gestation. Teratology 38(2):145\u2013155","journal-title":"Teratology"},{"issue":"3","key":"255_CR5","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/tera.1420360308","volume":"36","author":"M Aschner","year":"1987","unstructured":"Aschner M, Clarkson TW (1987) Mercury 203 distribution in pregnant andnonpregnant rats following systemic infusions with thiol-containing amino acids. Teratology 36(3):321\u2013328","journal-title":"Teratology"},{"key":"255_CR6","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1080\/00039896.1972.10666141","volume":"25","author":"G Birke","year":"1972","unstructured":"Birke G, Johnels AG, Plantin LO, Sjostrand B, Skerfving S, Westermark T (1972) Studies on humans exposed to methyl mercury through fish consumption. Arch Environ Health 25:77\u201391","journal-title":"Arch Environ Health"},{"key":"255_CR7","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0005-2728(97)00053-4","volume":"1321","author":"AA Boldyrev","year":"1997","unstructured":"Boldyrev AA, Bulygina ER, Kramarenko GG, Vanin AF (1997) Effect of nitroso compounds on Na+\/K+-ATPase. Biochim Biophy Acta 1321:243\u2013251","journal-title":"Biochim Biophy Acta"},{"issue":"4","key":"255_CR8","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1517\/17425255.2.4.629","volume":"2","author":"JJ Cali","year":"2006","unstructured":"Cali JJ, Ma D, Sobol M, Simpson DJ, Frackman S, Good TD, Daily WJ, Liu D. (2006) Luminogenic cytochrome P450 assays. Expert Opin Drug Metab Toxicol Aug; 2(4):629\u2013645","journal-title":"Expert Opin Drug Metab Toxicol Aug;"},{"key":"255_CR9","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1080\/00028896909343139","volume":"30","author":"H Cember","year":"1969","unstructured":"Cember H (1969) A model for the kinetics of mercury elimination. Am Ind Hyg Assoc J 30:367\u2013371","journal-title":"Am Ind Hyg Assoc J"},{"key":"255_CR10","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1080\/15287398109530018","volume":"7","author":"SK Chakrabarti","year":"1981","unstructured":"Chakrabarti SK (1981) Influence of mercury of the anesthetic response to and of distribution thiopental in rats. J Toxicol Env Health 7:765\u2013774","journal-title":"J Toxicol Env Health"},{"key":"255_CR11","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1124\/jpet.103.058818","volume":"308","author":"Y Chen","year":"2004","unstructured":"Chen Y, Ferguson SS, Negishi M, Goldstein JA (2004) Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor. J Pharmacol Exper Ther 308:495\u2013501","journal-title":"J Pharmacol Exper Ther"},{"issue":"1","key":"255_CR12","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0300-483X(01)00348-1","volume":"162","author":"JJ Chuu","year":"2001","unstructured":"Chuu JJ, Hsu CJ, Lin-Shiau SY (2001b) Abnormal auditory brainstem responses for mice treated with mercurial compounds: involvement of excessive nitric oxide. Toxicology 162(1):11\u201322","journal-title":"Toxicology"},{"issue":"2","key":"255_CR13","first-page":"128","volume":"25","author":"JJ Chuu","year":"2001","unstructured":"Chuu JJ, Liu SH, Lin-Shiau SY (2001c) Effects of methyl mercury, mercuric sulfide and cinnabar on active avoidance responses, Na+\/K+-ATPase activities and tissue mercury contents in rats. Proc Natl Sci Counc Repub China B 25(2):128\u2013136","journal-title":"Proc Natl Sci Counc Repub China B"},{"issue":"1","key":"255_CR14","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1046\/j.1472-8206.2003.00119.x","volume":"17","author":"AK Daly","year":"2003","unstructured":"Daly AK (2003) Pharmacogenetics of the major polymorphic metabolizing enzymes. Fundam Clin Pharmacol 17(1):27\u201341 (Review)","journal-title":"Fundam Clin Pharmacol"},{"issue":"1","key":"255_CR15","first-page":"10","volume":"108","author":"K Eto","year":"2006","unstructured":"Eto K (2006) Minamata disease: a neuropathological viewpoint. Seishin Shinkeigaku Zasshi 108(1):10\u201323 (Review)","journal-title":"Seishin Shinkeigaku Zasshi"},{"issue":"8","key":"255_CR16","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1007\/s00216-005-3143-2","volume":"381","author":"R Fernandez-Martinez","year":"2005","unstructured":"Fernandez-Martinez R, Rucandio MI (2005) Study of the suitability of HNO3 and HCl as extracting agents of mercury species in soils from cinnabar mines. Anal Bioanal Chem 381(8):1499\u20131506","journal-title":"Anal Bioanal Chem"},{"key":"255_CR67","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0006-8993(94)90386-7","volume":"653","author":"TD Foley","year":"1994","unstructured":"Foley TD, Rhoads DE (1994) Stimulation of synaptosomal Na+, K(+)-ATPase by ethanol: possible involvement of an isozyme-specific inhibitor of Na+, K(+)-ATPase. Brain Res 653:167\u2013172","journal-title":"Brain Res"},{"issue":"6","key":"255_CR17","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1007\/BF01721945","volume":"13","author":"RH Goldsmith","year":"1975","unstructured":"Goldsmith RH, Soares JH Jr (1975) Barbiturate potentiation in mercury poisoning. Bull Environ Contam Toxicol 13(6):737\u2013740","journal-title":"Bull Environ Contam Toxicol"},{"key":"255_CR18","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1111\/j.1471-4159.1986.tb00696.x","volume":"47","author":"D Guillaume","year":"1986","unstructured":"Guillaume D, Grisar T, Delgado Escueta AV (1986) Phenytoin dephosphorylates the catalytic subunit of the Na+\/K+-ATPase in C57 BL mice. J Neurochem 47:904\u2013911","journal-title":"J Neurochem"},{"issue":"1","key":"255_CR19","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0378-8741(95)01296-6","volume":"49","author":"AD Hardy","year":"1995","unstructured":"Hardy AD, Sutherland HH, Vaishnav R, Worthing MA (1995) A report on the composition of mercurials used in traditional medicines in Oman. J Ethnopharmacol 49(1):17\u201322","journal-title":"J Ethnopharmacol"},{"issue":"1","key":"255_CR20","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1081\/CLT-120018275","volume":"41","author":"BS Ho","year":"2003","unstructured":"Ho BS, Lin JL, Huang CC, Tsai YH, Lin MC (2003) Mercury vapor inhalation from Chinese red (Cinnabar). J Toxicol Clin Toxico 41(1):75\u201378","journal-title":"J Toxicol Clin Toxico"},{"key":"255_CR21","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/0041-008X(74)90173-2","volume":"27","author":"F Iverson","year":"1974","unstructured":"Iverson F, Downie RH, Trenholm HL, Paul C (1974) Accumulation and tissue distribution of mercury in the guinea pig during subacute administration of methyl mercury. Toxicol Appl Pharm 27:60\u201369","journal-title":"Toxicol Appl Pharm"},{"issue":"9","key":"255_CR22","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1248\/bpb.29.1983","volume":"29","author":"S Iwakawa","year":"2006","unstructured":"Iwakawa S, Miyashita K, Hashimoto Y, Kuroda T (2006) Effect of glimepiride and glibenclamide on S-warfarin 7-hydroxylation by human liver microsomes, recombinant human CYP2C9.1 and CYP2C9.3. Biol Pharm Bull 29(9):1983\u20131985","journal-title":"Biol Pharm Bull"},{"issue":"4","key":"255_CR23","first-page":"35","volume":"5","author":"M Kadiyska","year":"1979","unstructured":"Kadiyska M, Stoytchev T (1979) Influence of the acute intoxication with salts of some heavy metals on hexobarbital sleep and hexobarbital metabolism. Acta Physiol Pharmacol Bulg 5(4):35\u201343","journal-title":"Acta Physiol Pharmacol Bulg"},{"issue":"6","key":"255_CR24","first-page":"81","volume":"71","author":"PA Kaliman","year":"1999","unstructured":"Kaliman PA, Nikitchenko IV, Barannik TV, Sokol OA (1999) Metabolism of heme and hemoproteins in rat liver upon administration of mercuric chloride. Ukr Biokhim Zh 71(6):81\u201385","journal-title":"Ukr Biokhim Zh"},{"issue":"9","key":"255_CR25","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.2460\/ajvr.2003.64.1167","volume":"64","author":"JC Kawalek","year":"2003","unstructured":"Kawalek JC, Howard KD, Farrell DE, Derr J, Cope CV, Jackson JD, Myers MJ (2003) Effect of oral administration of low doses of pentobarbital on the induction of cytochrome P450 isoforms and cytochrome P450-mediated reactions in immature Beagles. Am J Vet Res 64(9):1167\u20131175","journal-title":"Am J Vet Res"},{"issue":"4","key":"255_CR26","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1620\/tjem.191.241","volume":"191","author":"CY Kim","year":"2000","unstructured":"Kim CY, Nakai K, Kameo S, Kurokawa N, Liu ZM, Satoh H (2000) Protective effect of melatonin on methylmercury-induced mortality in mice. Tohoku J Exp Med 191(4):241\u2013246","journal-title":"Tohoku J Exp Med"},{"issue":"1","key":"255_CR27","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.envres.2005.07.008","volume":"101","author":"L Knobeloch","year":"2006","unstructured":"Knobeloch L, Steenport D, Schrank C, Anderson H (2006) Methylmercury exposure in wisconsin: a case study series. Environ Res 101(1):113\u201322","journal-title":"Environ Res"},{"issue":"2","key":"255_CR28","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0378-4274(87)90179-2","volume":"36","author":"DA Kuznetsov","year":"1987","unstructured":"Kuznetsov DA, Zavijalov NV, Govorkov AV, Sibileva TM (1987) Methyl mercury-induced nonselective blocking of phosphorylation processes as a possible cause of protein synthesis inhibition in vitro and in vivo. Toxicol Lett 36(2):153\u2013160","journal-title":"Toxicol Lett"},{"issue":"Suppl 2","key":"255_CR29","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0168-8278(97)80492-8","volume":"26","author":"D Larrey","year":"1997","unstructured":"Larrey D, Pageaux GP (1997) Genetic predisposition to drug-induced hepatotoxicity. J Hepatol 26(Suppl 2):12\u201321 (Review)","journal-title":"J Hepatol"},{"issue":"4","key":"255_CR30","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1080\/15287399509532005","volume":"45","author":"JH Lee","year":"1995","unstructured":"Lee JH, Han DH (1995) Maternal and fetal toxicity of methylmercuric chloride administered to pregnant Fischer 344 rats. J Toxicol Environ Health 45(4):415\u2013425","journal-title":"J Toxicol Environ Health"},{"issue":"23","key":"255_CR31","first-page":"1809","volume":"30","author":"AH Liang","year":"2005","unstructured":"Liang AH, Xu YJ, Shang MF (2005) Analysis of adverse effects of cinnabar. Zhongguo Zhong Yao Za Zhi 30(23):1809\u20131811","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"key":"255_CR32","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0304-3940(99)00805-8","volume":"276","author":"CH Lin","year":"1999","unstructured":"Lin CH, Kang BH, Wong CH, Mao SH, Wan FJ (1999) Systemic administration of d-amphetamine induced a delayed production of nitric oxide in the straitum of rats. Neurosci Lett 276:141\u2013144","journal-title":"Neurosci Lett"},{"key":"255_CR33","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0014-2999(97)01133-3","volume":"333","author":"SH Liu","year":"1997","unstructured":"Liu SH, Sheu ZJ, Lin RH, Lin Shiau SY (1997) The in vivo effect of lipopoly-saccharide on neuromuscular transmission in the mouse. Eur J Pharmacol 333:241\u2013247","journal-title":"Eur J Pharmacol"},{"issue":"1\u20133","key":"255_CR34","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.scitotenv.2004.08.019","volume":"340","author":"J Loredo","year":"2005","unstructured":"Loredo J, Alvarez R, Ordonez A (2005) Release of toxic metals and metalloids from Los Rueldos mercury mine (Asturias, Spain). Sci Total Environ 340(1\u20133):247\u2013260","journal-title":"Sci Total Environ"},{"issue":"6","key":"255_CR35","first-page":"909","volume":"22","author":"Y Masubuchi","year":"1994","unstructured":"Masubuchi Y, Hosokawa S, Horie T, Suzuki T, Ohmori S, Kitada M, Narimatsu S (1994) Cytochrome P450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxylase and CYP1A2 as N-desisopropylase. Drug Metab Dispos 22(6):909\u2013915","journal-title":"Drug Metab Dispos"},{"issue":"1","key":"255_CR36","first-page":"198","volume":"J216","author":"T Nabeshima","year":"1981","unstructured":"Nabeshima T, Ho IK (1981) Pharmacological responses to pentobarbital in different strains of mice. J Pharmacol Exp Ther J216(1):198\u2013204","journal-title":"J Pharmacol Exp Ther"},{"key":"255_CR37","first-page":"427","volume":"34","author":"TM Park","year":"1994","unstructured":"Park TM (1994) Abnormal cortical unit activity of the reticular formation. Electromyo Clin Neurophysiol 34:427\u2013435","journal-title":"Electromyo Clin Neurophysiol"},{"issue":"3","key":"255_CR38","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1093\/alcalc\/36.3.193","volume":"36","author":"P Pokk","year":"2001","unstructured":"Pokk P, Sepp E, Vassiljev V, Vali M (2001) The effects of the nitric oxide synthase inhibitor 7-nitroindazole on the behaviour of mice after chronic ethanol administration. Alcohol Alcohol 36(3):193\u2013198","journal-title":"Alcohol Alcohol"},{"issue":"2","key":"255_CR39","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1124\/jpet.102.033837","volume":"302","author":"JL Raucy","year":"2002","unstructured":"Raucy JL, Mueller L, Duan K, Allen SW, Strom S, Lasker JM (2002) Expression and induction of CYP2C P450 enzymes in primary cultures of human hepatocytes. J Pharmacol Exp Ther 302(2):475\u2013482","journal-title":"J Pharmacol Exp Ther"},{"key":"255_CR40","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/0006-2952(93)90530-A","volume":"46","author":"TT Rohn","year":"1993","unstructured":"Rohn TT, Hinds TR, Vincenzi FF (1993) Ion transport ATPases as targets for free radical damage. Protection by an aminosteroid of the Ca2+ pump ATPase and Na+\/K+ pump ATPase of human red blood cell membranes. Biochem Pharmacol 46:525\u2013534","journal-title":"Biochem Pharmacol"},{"issue":"12","key":"255_CR41","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1124\/dmd.104.000208","volume":"32","author":"J Sahi","year":"2004","unstructured":"Sahi J, Stern RH, Milad MA, Rose KA, Gibson G, Zheng X, Stilgenbauer L, Sadagopan N, Jolley S, Gilbert D, LeCluyse EL (2004) Effects of avasimibe on cytochrome P450 2C9 expression in vitro and in vivo. Drug Metab Dispos 32(12):1370\u20131376","journal-title":"Drug Metab Dispos"},{"issue":"2","key":"255_CR42","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1265\/jjh.45.717","volume":"45","author":"K Sano","year":"1990","unstructured":"Sano K, Shimojo N, Yamaguchi S (1990) Effects of methylmercury on ethanol induced sleeping time of mice. Nippon Eiseigaku Zasshi 45(2):717\u2013722","journal-title":"Nippon Eiseigaku Zasshi"},{"issue":"23","key":"255_CR43","doi-asserted-by":"crossref","first-page":"2868","DOI":"10.1001\/jama.292.23.2868","volume":"292","author":"RB Saper","year":"2004","unstructured":"Saper RB, Kales SN, Paquin J, Burns MJ, Eisenberg DM, Davis RB, Phillips RS (2004) Heavy metal content of ayurvedic herbal medicine products. JAMA 292(23):2868\u20132873","journal-title":"JAMA"},{"issue":"6","key":"255_CR44","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1213\/01.ANE.0000184127.67866.2E","volume":"101","author":"Y Sato","year":"2005","unstructured":"Sato Y, Seo N, Kobahashi E (2005) The dosing-time dependent effects of intravenous hypnotics in mice. Anesth Analg 101(6):1706\u20131708","journal-title":"Anesth Analg"},{"key":"255_CR45","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1539-6924.1997.tb00896.x","volume":"17","author":"RA Schoof","year":"1997","unstructured":"Schoof RA, Nielsen JB (1997) Evaluation of methods for assessing the oral bioavailability of inorganic mercury in soil. Risk Anal 17:545\u2013555 (Review)","journal-title":"Risk Anal"},{"key":"255_CR46","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0006-8993(98)00400-4","volume":"798","author":"M Shinyashiki","year":"1998","unstructured":"Shinyashiki M, Kumagai Y, Nakajima H, Nagafune J, Homma Takeda S, Sagai M, Shimojo N (1998) Differential changes in rat brain nitric oxide synthase in vivo and in vitro by methylmercury. Brain Res 798:147\u2013155","journal-title":"Brain Res"},{"issue":"3","key":"255_CR47","first-page":"29","volume":"4","author":"T Stoytchev","year":"1978","unstructured":"Stoytchev T, Krotev L (1978) Effect of subacute intoxication with some heavy metals on hexobarbital sleep and metabolism. Acta Physiol Pharmacol Bulg 4(3):29\u201335","journal-title":"Acta Physiol Pharmacol Bulg"},{"issue":"6","key":"255_CR48","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1517\/17425255.2.6.895","volume":"2","author":"M Strolin Benedetti","year":"2006","unstructured":"Strolin Benedetti M, Whomsley R, Baltes E (2006) Involvement of enzymes other than CYPs in the oxidative metabolism of xenobiotics. Expert Opin Drug Metab Toxicol 2(6):895\u2013921 (Review)","journal-title":"Expert Opin Drug Metab Toxicol"},{"issue":"3","key":"255_CR49","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0300-483X(86)90025-9","volume":"39","author":"MQ Su","year":"1986","unstructured":"Su MQ, Okita GT (1986) Effects of methylmercury on hypnotic action of hexobarbital, liver hydroxylase and cytochrome P-450 in mice. Toxicology 39(3):233\u2013245","journal-title":"Toxicology"},{"issue":"1","key":"255_CR50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.abb.2004.05.015","volume":"429","author":"H Suzuki","year":"2004","unstructured":"Suzuki H, Kneller MB, Rock DA, Jones JP, Trager WF, Rettie AE (2004) Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors. Arch Biochem Biophys 429(1):1\u201315","journal-title":"Arch Biochem Biophys"},{"issue":"6","key":"255_CR51","first-page":"719","volume":"56","author":"S Talarek","year":"2004","unstructured":"Talarek S, Fidecka S (2004) Involvement of nitricoxidergic system in thehypnotic effects of benzodiazepines in mice. Pol J Pharmacol 56(6):719\u2013726","journal-title":"Pol J Pharmacol"},{"issue":"1","key":"255_CR52","first-page":"27","volume":"J54","author":"S Talarek","year":"2002","unstructured":"Talarek S, Fidecka S (2002) Role of nitric oxide in benzodiazepines-induced antinociception in mice. Pol J Pharmacol J54(1):27\u201334","journal-title":"Pol J Pharmacol"},{"issue":"3","key":"255_CR53","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/cbdv.200790032","volume":"4","author":"B Testa","year":"2007","unstructured":"Testa B, Kramer SD (2007) The biochemistry of drug metabolism\u2014an introduction: part 2. Redox reactions and their enzymes. Chem Biodivers 4(3):257\u2013405 Review","journal-title":"Chem Biodivers"},{"key":"255_CR54","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/00008506-199901000-00007","volume":"11","author":"PH Tonner","year":"1999","unstructured":"Tonner PH, Scholz J, Schlamp N, Schulteam Esch J (1999) Inhibition of nitric oxide metabolism enhances the hypnotic-anesthetic action of the alpha2-adrenoceptor agonist dexmedetomidine in vivo. J Neurosurg Anesth 11:37\u201341","journal-title":"J Neurosurg Anesth"},{"issue":"5","key":"255_CR55","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1289\/ehp.7743","volume":"113","author":"L Trasande","year":"2006","unstructured":"Trasande L, Landrigan PJ, Schechter C (2006) Public health and economic consequences of methyl mercury toxicity to the developing brain. Environ Health Perspect 113(5):590\u2013596","journal-title":"Environ Health Perspect"},{"key":"255_CR56","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.etap.2004.12.045","volume":"19","author":"T Vezer","year":"2005","unstructured":"Vezer T, Papp A, Kurunczi A, Parducz A, Naray M, Nagymajtenyi L (2005) Behavioral and neurotoxic effects seen during and after subchronic exposure of rats to organic mercury. Environ Toxicol Pharmacol 19:785\u2013796","journal-title":"Environ Toxicol Pharmacol"},{"issue":"7","key":"255_CR57","first-page":"639","volume":"28","author":"JH Wang","year":"2003","unstructured":"Wang JH, Ye ZG, Liang AH, Xue BY, Wang YS, Wang ZM, Wang L, Li CY, Zhang J, Huang N, Jin AY (2003) Absorption and distribution of mercury and arsenic from realgar and cinnabar of angong niuhuang pill in normal rats and rats with cerebral ischemia. Zhongguo Zhong Yao Za Zhi 28(7):639\u2013642","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"issue":"3","key":"255_CR58","first-page":"268","volume":"11","author":"WH Wang","year":"1990","unstructured":"Wang WH, Yu ZH, Cai M, Xu XM, Wu GP (1990) Antifertility actions of gossypol derivatives and analogues. Acta Pharmacologica Sinica. 11(3):268\u2013271","journal-title":"Acta Pharmacologica Sinica"},{"issue":"5","key":"255_CR59","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/0006-2952(94)90475-8","volume":"47","author":"RJ Weaver","year":"1994","unstructured":"Weaver RJ, Thompson S, Smith G, Dickins M, Elcombe CR, Mayer RT, Burke MD (1994) A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes. Biochem Pharmacol 47(5):763\u2013773","journal-title":"Biochem Pharmacol"},{"key":"255_CR60","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1006\/enrs.1997.3748","volume":"74","author":"LG Wild","year":"1997","unstructured":"Wild LG, Ortega HG, Lopez M, Salvaggio JE (1997) Immune system alteration in the rat after indirect exposure to methyl mercury chloride or methyl mercury sulfide. Environ Res 74:34\u201342","journal-title":"Environ Res"},{"issue":"3","key":"255_CR61","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0048-9697(97)05474-0","volume":"199","author":"M Yamada","year":"1997","unstructured":"Yamada M, Minami T, Yamada G, Tohno Y, Tohno S, Ikeda Y, Tashiro T, Kohno Y, Kawakami K (1997) Different element ratios of red cosmetics excavated from ancient burials of Japan. Sci Total Environ 199(3):293\u2013298","journal-title":"Sci Total Environ"},{"issue":"2","key":"255_CR62","first-page":"227","volume":"60","author":"I Yamamoto","year":"1985","unstructured":"Yamamoto I (1985) Studies on the behavior of mercury and selenium in blood of mice injected with those elements. Hokkaido Igaku Zasshi 60(2):227\u2013240","journal-title":"Hokkaido Igaku Zasshi"},{"issue":"3","key":"255_CR63","first-page":"381","volume":"19","author":"I Yamamoto","year":"1978","unstructured":"Yamamoto I, Ho IK (1978) Sensitivity to continuous administration of pentobarbital in different strains of mice. Res Commun Chem Pathol Pharmacol 19(3):381\u2013388","journal-title":"Res Commun Chem Pathol Pharmacol"},{"issue":"7","key":"255_CR64","first-page":"636","volume":"28","author":"ZG Ye","year":"2003","unstructured":"Ye ZG, Wang JH, Liang AH, Xue BY, Wang YS, Wang ZM, Wang L, Li CY, Zhang J, Huang N, Jin AY (2003) Comparative studies on pharmacological effects of angong niuhuang pill with its simplified prescription. Zhongguo Zhong Yao Za Zhi 28(7):636\u2013639","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"issue":"5","key":"255_CR65","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1093\/jat\/26.5.286","volume":"26","author":"CC Yen","year":"2002","unstructured":"Yen CC, Liu SH, Chen WK, Lin RH, Lin-Shiau SY (2002) Tissue distribution of different mercurial compounds analyzed by the improved FI-CVAAS. J Anal Toxicol 26(5):286\u2013295","journal-title":"J Anal Toxicol"},{"key":"255_CR66","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0300-483X(86)90108-3","volume":"41","author":"TS Yeoh","year":"1986","unstructured":"Yeoh TS, Lee AS, Lee HS (1986) Absorption of mercuric sulphide following oral administration in mice. Toxicology 41:107\u2013111","journal-title":"Toxicology"},{"issue":"2","key":"255_CR68","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1093\/toxsci\/67.2.256","volume":"67","author":"YH Young","year":"2002","unstructured":"Young YH, Chuu JJ, Liu SH, Lin-Shiau SY (2002) Neurotoxic mechanism of cinnabar and mercuric sulfide on the vestibulo-ocular reflex system of guinea pigs. Toxicol Sci 67(2):256\u2013263","journal-title":"Toxicol Sci"}],"container-title":["Archives of Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00204-007-0255-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00204-007-0255-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00204-007-0255-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T15:21:58Z","timestamp":1558624918000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00204-007-0255-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11,30]]},"references-count":68,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["255"],"URL":"https:\/\/doi.org\/10.1007\/s00204-007-0255-9","relation":{},"ISSN":["0340-5761","1432-0738"],"issn-type":[{"value":"0340-5761","type":"print"},{"value":"1432-0738","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,11,30]]}}}