{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T01:14:47Z","timestamp":1760577287210},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2009,5,16]],"date-time":"2009-05-16T00:00:00Z","timestamp":1242432000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Toxicol"],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1007\/s00204-009-0431-1","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T12:59:55Z","timestamp":1242392395000},"page":"835-849","source":"Crossref","is-referenced-by-count":24,"title":["Trichloroethylene liver toxicity in mouse and rat: microarray analysis reveals species differences in gene expression"],"prefix":"10.1007","volume":"83","author":[{"given":"Yuri","family":"Sano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Nakashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyuki","family":"Yoshioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norihito","family":"Etho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuo","family":"Nomiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Nishiwaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Takebayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyuki","family":"Oame","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,5,16]]},"reference":[{"key":"431_CR1","doi-asserted-by":"crossref","first-page":"52390","DOI":"10.1074\/jbc.M409347200","volume":"279","author":"SP Anderson","year":"2004","unstructured":"Anderson SP, Howroyd P, Liu J, Qian X, Bahnemann R, Swanson C, Kwak MK, Kensler TW, Corton JC (2004) The transcriptional response to a peroxisome proliferator-activated receptor alpha agonist includes increased expression of proteome maintenance genes. J Biol Chem 279:52390\u201352398. doi: 10.1074\/jbc.M409347200","journal-title":"J Biol Chem"},{"key":"431_CR2","first-page":"1","volume":"56","author":"HK Bojes","year":"1996","unstructured":"Bojes HK, Thurman RG (1996) Peroxisome proliferators activate Kupffer cells in vivo. Cancer Res 56:1\u20134","journal-title":"Cancer Res"},{"key":"431_CR3","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.tox.2004.07.015","volume":"206","author":"S Bosgra","year":"2005","unstructured":"Bosgra S, Mennes W, Seinen W (2005a) Proceedings in uncovering the mechanism behind peroxisome proliferator-induced hepatocarcinogenesis. Toxicology 206:309\u2013323. doi: 10.1016\/j.tox.2004.07.015","journal-title":"Toxicology"},{"key":"431_CR4","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.tox.2004.07.015","volume":"206","author":"S Bosgra","year":"2005","unstructured":"Bosgra S, Mennes W, Seinen W (2005b) Proceedings in uncovering the mechanism behind peroxisome proliferator-induced hepatocarcinogenesis. Toxicology 206:309\u2013323. doi: 10.1016\/j.tox.2004.07.015","journal-title":"Toxicology"},{"issue":"3","key":"431_CR5","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0300-483X(90)90195-M","volume":"63","author":"R Bull","year":"1990","unstructured":"Bull R, Sanchez I, Nelson M, Larson J, Lansing A (1990) Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate. Toxicology 63(3):341\u2013359. doi: 10.1016\/0300-483X(90)90195-M","journal-title":"Toxicology"},{"key":"431_CR6","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1006\/taap.2002.9427","volume":"182","author":"RJ Bull","year":"2002","unstructured":"Bull RJ, Orner GA, Cheng RS, Stillwell L, Stauber AJ, Sasser LB, Lingohr MK, Thrall BD (2002) Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene. Toxicol Appl Pharmacol 182:55\u201365. doi: 10.1006\/taap.2002.9427","journal-title":"Toxicol Appl Pharmacol"},{"key":"431_CR8","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.cell.2006.01.021","volume":"124","author":"L Chang","year":"2006","unstructured":"Chang L, Kamata H, Solinas G, Luo JL, Maeda S, Venuprasad K, Liu YC, Karin M (2006) The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover. Cell 124:601\u2013613. doi: 10.1016\/j.cell.2006.01.021","journal-title":"Cell"},{"key":"431_CR9","doi-asserted-by":"crossref","first-page":"18451","DOI":"10.1074\/jbc.M601720200","volume":"281","author":"YT Chou","year":"2006","unstructured":"Chou YT, Yang YC (2006) Post-transcriptional control of Cited2 by transforming growth factor beta. Regulation via Smads and Cited2 coding region. J Biol Chem 281:18451\u201318462. doi: 10.1074\/jbc.M601720200","journal-title":"J Biol Chem"},{"key":"431_CR10","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/ng0502-19","volume":"31","author":"K Dahlquist","year":"2002","unstructured":"Dahlquist K, Salomonis N, Vranizan K, Lawlor S, Conklin B (2002) GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat Genet 31:19\u201320. doi: 10.1038\/ng0502-19","journal-title":"Nat Genet"},{"key":"431_CR11","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0041-008X(85)90135-8","volume":"79","author":"CR Elcombe","year":"1985","unstructured":"Elcombe CR, Rose MS, Pratt IS (1985) Biochemical, histological, and ultrastructural changes in rat and mouse liver following the administration of trichloroethylene: possible relevance to species differences in hepatocarcinogenicity. Toxicol Appl Pharmacol 79:365\u2013376. doi: 10.1016\/0041-008X(85)90135-8","journal-title":"Toxicol Appl Pharmacol"},{"key":"431_CR42","unstructured":"European Union (2004) European Union Risk Assessment Report: trichloroethylene. First priority list, vol 31. European Chemicals Bureau, European Commission, EUR 21057 EN. http:\/\/ecb.jrc.it\/DOCUMENTS\/Existing-Chemicals\/RISK_ASSESSMENT\/REPORT\/trichloroethylenereport018.pdf"},{"key":"431_CR43","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1053\/j.gastro.2007.03.033","volume":"132","author":"F Geisler","year":"2007","unstructured":"Geisler F, Algul H, Paxian S, Schmid RM (2007) Genetic inactivation of RelA\/p65 sensitizes adult mouse hepatocytes to TNF-induced apoptosis in vivo and in vitro. Gastroenterology 132:2489\u20132503","journal-title":"Gastroenterology"},{"key":"431_CR13","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.taap.2007.08.017","volume":"225","author":"PJ Hendriksen","year":"2007","unstructured":"Hendriksen PJ, Freidig AP, Jonker D, Thissen U, Bogaards JJ, Mumtaz MM, Groten JP, Stierum RH (2007) Transcriptomics analysis of interactive effects of benzene, trichloroethylene and methyl mercury within binary and ternary mixtures on the liver and kidney following subchronic exposure in the rat. Toxicol Appl Pharmacol 225:171\u2013188. doi: 10.1016\/j.taap.2007.08.017","journal-title":"Toxicol Appl Pharmacol"},{"key":"431_CR14","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1080\/713608372","volume":"33","author":"JE Klaunig","year":"2003","unstructured":"Klaunig JE, Babich MA, Baetcke KP, Cook JC, Corton JC, David RM, DeLuca JG, Lai DY, McKee RH, Peters JM, Roberts RA, Fenner-Crisp PA (2003) PPARalpha agonist-induced rodent tumors: modes of action and human relevance. Crit Rev Toxicol 33:655\u2013780. doi: 10.1080\/713608372","journal-title":"Crit Rev Toxicol"},{"key":"431_CR15","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0092-8674(00)80753-9","volume":"97","author":"DM Koepp","year":"1999","unstructured":"Koepp DM, Harper JW, Elledge SJ (1999) How the cyclin became a cyclin: regulated proteolysis in the cell cycle. Cell 97:431\u2013434. doi: 10.1016\/S0092-8674(00)80753-9","journal-title":"Cell"},{"key":"431_CR17","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.tox.2004.06.014","volume":"203","author":"AR Laughter","year":"2004","unstructured":"Laughter AR, Dunn CS, Swanson CL, Howroyd P, Cattley RC, Corton JC (2004) Role of the peroxisome proliferator-activated receptor alpha (PPARalpha) in responses to trichloroethylene and metabolites, trichloroacetate and dichloroacetate in mouse liver. Toxicology 203:83\u201398. doi: 10.1016\/j.tox.2004.06.014","journal-title":"Toxicology"},{"key":"431_CR18","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1038\/ng1481","volume":"36","author":"JS Lee","year":"2004","unstructured":"Lee JS, Chu IS, Mikaelyan A, Calvisi DF, Heo J, Reddy JK, Thorgeirsson SS (2004) Application of comparative functional genomics to identify best-fit mouse models to study human cancer. Nat Genet 36:1306\u20131311. doi: 10.1038\/ng1481","journal-title":"Nat Genet"},{"key":"431_CR19","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/bies.10204","volume":"25","author":"A Lin","year":"2003","unstructured":"Lin A (2003) Activation of the JNK signaling pathway: breaking the brake on apoptosis. Bioessays 25:17\u201324. doi: 10.1002\/bies.10204","journal-title":"Bioessays"},{"key":"431_CR20","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.molcel.2005.12.020","volume":"21","author":"J Liu","year":"2006","unstructured":"Liu J, Yang D, Minemoto Y, Leitges M, Rosner MR, Lin A (2006) NF-kappaB is required for UV-induced JNK activation via induction of PKCdelta. Mol Cell 21:467\u2013480. doi: 10.1016\/j.molcel.2005.12.020","journal-title":"Mol Cell"},{"key":"431_CR21","first-page":"465","volume":"12","author":"PK Majumder","year":"2001","unstructured":"Majumder PK, Mishra NC, Sun X, Bharti A, Kharbanda S, Saxena S, Kufe D (2001) Targeting of protein kinase C delta to mitochondria in the oxidative stress response. Cell Growth Differ 12:465\u2013470","journal-title":"Cell Growth Differ"},{"key":"431_CR22","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/35043051","volume":"1","author":"J Massague","year":"2000","unstructured":"Massague J (2000) How cells read TGF-beta signals. Nat Rev Mol Cell Biol 1:169\u2013178. doi: 10.1038\/35043051","journal-title":"Nat Rev Mol Cell Biol"},{"key":"431_CR23","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0378-4347(99)00282-0","volume":"732","author":"S Muralidhara","year":"1999","unstructured":"Muralidhara S, Bruckner JV (1999) Simple method for rapid measurement of trichloroethylene and its major metabolites in biological samples. J Chromatogr B Biomed Sci Appl 732:145\u2013153. doi: 10.1016\/S0378-4347(99)00282-0","journal-title":"J Chromatogr B Biomed Sci Appl"},{"key":"431_CR24","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1128\/MCB.24.1.144-153.2004","volume":"24","author":"LO Murphy","year":"2004","unstructured":"Murphy LO, MacKeigan JP, Blenis J (2004) A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration. Mol Cell Biol 24:144\u2013153. doi: 10.1128\/MCB.24.1.144-153.2004","journal-title":"Mol Cell Biol"},{"key":"431_CR41","unstructured":"National Academy of Sciences (NAS) (2006) Assessing the human health risks of trichloroethylene: key scientific issues. BEST-K-03-06-A. http:\/\/www8.nationalacademies.org\/cp\/projectview.aspx?key=127"},{"key":"431_CR25","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0898-6568(01)00260-1","volume":"14","author":"CJ Pauley","year":"2002","unstructured":"Pauley CJ, Ledwith BJ, Kaplanski C (2002) Peroxisome proliferators activate growth regulatory pathways largely via peroxisome proliferator-activated receptor alpha-independent mechanisms. Cell Signal 14:351\u2013358. doi: 10.1016\/S0898-6568(01)00260-1","journal-title":"Cell Signal"},{"key":"431_CR26","doi-asserted-by":"crossref","first-page":"13452","DOI":"10.1074\/jbc.272.20.13452","volume":"272","author":"CL Rokos","year":"1997","unstructured":"Rokos CL, Ledwith BJ (1997) Peroxisome proliferators activate extracellular signal-regulated kinases in immortalized mouse liver cells. J Biol Chem 272:13452\u201313457. doi: 10.1074\/jbc.272.20.13452","journal-title":"J Biol Chem"},{"key":"431_CR27","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1093\/carcin\/18.8.1453","volume":"18","author":"ML Rose","year":"1997","unstructured":"Rose ML, Germolec DR, Schoonhoven R, Thurman RG (1997) Kupffer cells are causally responsible for the mitogenic effect of peroxisome proliferators. Carcinogenesis 18:1453\u20131456. doi: 10.1093\/carcin\/18.8.1453","journal-title":"Carcinogenesis"},{"key":"431_CR28","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1093\/carcin\/19.7.1217","volume":"19","author":"I Rusyn","year":"1998","unstructured":"Rusyn I, Tsukamoto H, Thurman RG (1998) WY-14 643 rapidly activates nuclear factor kappaB in Kupffer cells before hepatocytes. Carcinogenesis 19:1217\u20131222. doi: 10.1093\/carcin\/19.7.1217","journal-title":"Carcinogenesis"},{"key":"431_CR29","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1080\/10408440600779065","volume":"36","author":"I Rusyn","year":"2006","unstructured":"Rusyn I, Peters JM, Cunningham ML (2006) Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver. Crit Rev Toxicol 36:459\u2013479. doi: 10.1080\/10408440600779065","journal-title":"Crit Rev Toxicol"},{"key":"431_CR30","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1289\/ehp.8949","volume":"114","author":"CS Scott","year":"2006","unstructured":"Scott CS, Chiu WA (2006) Trichloroethylene cancer epidemiology: a consideration of select issues. Environ Health Perspect 114:1471\u20131478","journal-title":"Environ Health Perspect"},{"key":"431_CR31","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","volume":"102","author":"A Subramanian","year":"2005","unstructured":"Subramanian A, Tamayo P, Mootha V, Mukherjee S, Ebert B, Gillette M, Paulovich A, Pomeroy S, Golub T, Lander E, Mesirov J (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102:15545\u201315550. doi: 10.1073\/pnas.0506580102","journal-title":"Proc Natl Acad Sci USA"},{"key":"431_CR32","doi-asserted-by":"crossref","first-page":"5068","DOI":"10.1038\/sj.onc.1207690","volume":"23","author":"H Suzuki","year":"2004","unstructured":"Suzuki H, Yagi K, Kondo M, Kato M, Miyazono K, Miyazawa K (2004) c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements. Oncogene 23:5068\u20135076. doi: 10.1038\/sj.onc.1207690","journal-title":"Oncogene"},{"key":"431_CR33","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1038\/sj.emboj.7600501","volume":"24","author":"R Thyss","year":"2005","unstructured":"Thyss R, Virolle V, Imbert V, Peyron JF, Aberdam D, Virolle T (2005) NF-kappaB\/Egr-1\/Gadd45 are sequentially activated upon UVB irradiation to mediate epidermal cell death. EMBO J 24:128\u2013137. doi: 10.1038\/sj.emboj.7600501","journal-title":"EMBO J"},{"key":"431_CR34","doi-asserted-by":"crossref","first-page":"24053","DOI":"10.1074\/jbc.M401489200","volume":"279","author":"ES Tien","year":"2004","unstructured":"Tien ES, Davis JW, Vanden Heuvel JP (2004) Identification of the CREB-binding protein\/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor alpha coregulator. J Biol Chem 279:24053\u201324063. doi: 10.1074\/jbc.M401489200","journal-title":"J Biol Chem"},{"key":"431_CR35","doi-asserted-by":"crossref","first-page":"14484","DOI":"10.1074\/jbc.C400005200","volume":"279","author":"M Wan","year":"2004","unstructured":"Wan M, Tang Y, Tytler EM, Lu C, Jin B, Vickers SM, Yang L, Shi X, Cao X (2004) Smad4 protein stability is regulated by ubiquitin ligase SCF beta-TrCP1. J Biol Chem 279:14484\u201314487. doi: 10.1074\/jbc.C400005200","journal-title":"J Biol Chem"},{"key":"431_CR36","doi-asserted-by":"crossref","first-page":"31686","DOI":"10.1074\/jbc.M504447200","volume":"280","author":"Y Weng","year":"2005","unstructured":"Weng Y, DiRusso CC, Reilly AA, Black PN, Ding X (2005) Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype. J Biol Chem 280:31686\u201331698. doi: 10.1074\/jbc.M504447200","journal-title":"J Biol Chem"},{"key":"431_CR37","unstructured":"Woodworth GG (2004) Biostatistics: a Bayesian introduction Wiley-Interscience, Hoboken"},{"key":"431_CR38","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/toxsci\/kfl002","volume":"92","author":"S Xiao","year":"2006","unstructured":"Xiao S, Anderson SP, Swanson C, Bahnemann R, Voss KA, Stauber AJ, Corton JC (2006) Activation of peroxisome proliferator-activated receptor alpha enhances apoptosis in the mouse liver. Toxicol Sci 92:368\u2013377. doi: 10.1093\/toxsci\/kfl002","journal-title":"Toxicol Sci"},{"key":"431_CR39","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.cell.2006.06.050","volume":"126","author":"X Yang","year":"2006","unstructured":"Yang X, Downes M, Yu RT, Bookout AL, He W, Straume M, Mangelsdorf DJ, Evans RM (2006) Nuclear receptor expression links the circadian clock to metabolism. Cell 126:801\u2013810. doi: 10.1016\/j.cell.2006.06.050","journal-title":"Cell"},{"key":"431_CR40","doi-asserted-by":"crossref","first-page":"11324","DOI":"10.1073\/pnas.95.19.11324","volume":"95","author":"ZK Yu","year":"1998","unstructured":"Yu ZK, Gervais JL, Zhang H (1998) Human CUL-1 associates with the SKP1\/SKP2 complex and regulates p21(CIP1\/WAF1) and cyclin D proteins. Proc Natl Acad Sci USA 95:11324\u201311329. doi: 10.1073\/pnas.95.19.11324","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Archives of Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00204-009-0431-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00204-009-0431-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00204-009-0431-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T15:22:04Z","timestamp":1558624924000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00204-009-0431-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,16]]},"references-count":40,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["431"],"URL":"https:\/\/doi.org\/10.1007\/s00204-009-0431-1","relation":{},"ISSN":["0340-5761","1432-0738"],"issn-type":[{"value":"0340-5761","type":"print"},{"value":"1432-0738","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,16]]}}}