{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T02:05:18Z","timestamp":1725588318899},"reference-count":55,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2012,7,19]],"date-time":"2012-07-19T00:00:00Z","timestamp":1342656000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Toxicol"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1007\/s00204-012-0907-2","type":"journal-article","created":{"date-parts":[[2012,7,19]],"date-time":"2012-07-19T23:29:44Z","timestamp":1342740584000},"page":"1899-1910","source":"Crossref","is-referenced-by-count":6,"title":["The rat prepubertal uterine myometrium and not the luminal epithelium is predominantly affected by a chronic dietary genistein exposure"],"prefix":"10.1007","volume":"86","author":[{"given":"Frank Josef","family":"M\u00f6ller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinna","family":"Ledwig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Zierau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Torsten","family":"Hertrampf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisela H.","family":"Degen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Diel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fcnter","family":"Vollmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,7,19]]},"reference":[{"issue":"6","key":"907_CR1","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/S1470-2045(02)00777-5","volume":"3","author":"H Adlercreutz","year":"2002","unstructured":"Adlercreutz H (2002) Phyto-oestrogens and cancer. Lancet Oncol 3(6):364\u2013373","journal-title":"Lancet Oncol"},{"issue":"12","key":"907_CR2","doi-asserted-by":"crossref","first-page":"5592","DOI":"10.1016\/S0021-9258(18)45614-1","volume":"262","author":"T Akiyama","year":"1987","unstructured":"Akiyama T, Ishida J, Nakagawa S, Ogawara H, Watanabe S, Itoh N, Shibuya M, Fukami Y (1987) Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 262(12):5592\u20135595","journal-title":"J Biol Chem"},{"issue":"3","key":"907_CR3","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1006\/rtph.1997.1108","volume":"25","author":"J Ashby","year":"1997","unstructured":"Ashby J, Odum J, Foster JR (1997) Activity of raloxifene in immature and ovariectomized rat uterotrophic assays. Regul Toxicol Pharmacol 25(3):226\u2013231","journal-title":"Regul Toxicol Pharmacol"},{"issue":"1","key":"907_CR4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1124\/mol.54.1.105","volume":"54","author":"T Barkhem","year":"1998","unstructured":"Barkhem T, Carlsson B, Nilsson Y, Enmark E, Gustafsson J, Nilsson S (1998) Differential response of estrogen receptor alpha and estrogen receptor beta to partial estrogen agonists\/antagonists. Mol Pharmacol 54(1):105\u2013112","journal-title":"Mol Pharmacol"},{"issue":"1","key":"907_CR5","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.mce.2009.07.032","volume":"314","author":"A Bliedtner","year":"2009","unstructured":"Bliedtner A, Zierau O, Albrecht S, Liebhaber S, Vollmer G (2009) Effects of genistein and estrogen receptor subtype-specific agonists in ArKO mice following different administration routes. Mol Cell Endocrinol 314(1):41\u201352","journal-title":"Mol Cell Endocrinol"},{"issue":"8","key":"907_CR6","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1289\/ehp.00108701","volume":"108","author":"KB Bouker","year":"2000","unstructured":"Bouker KB, Hilakivi-Clarke L (2000) Genistein: does it prevent or promote breast cancer? Environ Health Perspect 108(8):701\u2013708","journal-title":"Environ Health Perspect"},{"issue":"2","key":"907_CR7","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1093\/toxsci\/51.2.236","volume":"51","author":"M Casanova","year":"1999","unstructured":"Casanova M, You L, Gaido KW, Archibeque-Engle S, Janszen DB, Heck HA (1999) Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro. Toxicol Sci 51(2):236\u2013244","journal-title":"Toxicol Sci"},{"issue":"Suppl 1","key":"907_CR8","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/j.psyneuen.2009.05.004","volume":"34","author":"TD Charlier","year":"2009","unstructured":"Charlier TD (2009) Importance of steroid receptor coactivators in the modulation of steroid action on brain and behavior. Psychoneuroendocrinology 34(Suppl 1):S20\u2013S29","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"907_CR9","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","volume":"162","author":"P Chomczynski","year":"1987","unstructured":"Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162(1):156\u2013159","journal-title":"Anal Biochem"},{"key":"907_CR10","unstructured":"Clark J, Markaverich B (1988) Actions of ovarian steroids. In: Knobil E, Neill J (eds) The physiology of reproduction, vol 1. Raven Press, New York, pp 675\u2013724"},{"issue":"7","key":"907_CR11","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1055\/s-2003-41122","volume":"69","author":"P Cos","year":"2003","unstructured":"Cos P, De Bruyne T, Apers S, Vanden Berghe D, Pieters L, Vlietinck AJ (2003) Phytoestrogens: recent developments. Planta Med 69(7):589\u2013599","journal-title":"Planta Med"},{"issue":"1\u20132","key":"907_CR12","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0303-7207(00)00405-6","volume":"173","author":"MS Cotroneo","year":"2001","unstructured":"Cotroneo MS, Wang J, Eltoum IA, Lamartiniere CA (2001) Sex steroid receptor regulation by genistein in the prepubertal rat uterus. Mol Cell Endocrinol 173(1\u20132):135\u2013145","journal-title":"Mol Cell Endocrinol"},{"issue":"1\u20132","key":"907_CR13","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.mce.2004.04.006","volume":"221","author":"P Diel","year":"2004","unstructured":"Diel P, Geis RB, Caldarelli A, Schmidt S, Leschowsky UL, Voss A, Vollmer G (2004a) The differential ability of the phytoestrogen genistein and of estradiol to induce uterine weight and proliferation in the rat is associated with a substance specific modulation of uterine gene expression. Mol Cell Endocrinol 221(1\u20132):21\u201332","journal-title":"Mol Cell Endocrinol"},{"issue":"4","key":"907_CR14","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s00204-003-0535-y","volume":"78","author":"P Diel","year":"2004","unstructured":"Diel P, Schmidt S, Vollmer G, Janning P, Upmeier A, Michna H, Bolt HM, Degen GH (2004b) Comparative responses of three rat strains (DA\/Han, Sprague-Dawley and Wistar) to treatment with environmental estrogens. Arch Toxicol 78(4):183\u2013193","journal-title":"Arch Toxicol"},{"issue":"1\u20135","key":"907_CR15","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jsbmb.2006.09.022","volume":"102","author":"P Diel","year":"2006","unstructured":"Diel P, Hertrampf T, Seibel J, Laudenbach-Leschowsky U, Kolba S, Vollmer G (2006) Combinatorial effects of the phytoestrogen genistein and of estradiol in uterus and liver of female Wistar rats. J Steroid Biochem Mol Biol 102(1\u20135):60\u201370","journal-title":"J Steroid Biochem Mol Biol"},{"issue":"3","key":"907_CR16","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.reprotox.2005.09.007","volume":"21","author":"DR Doerge","year":"2006","unstructured":"Doerge DR, Twaddle NC, Churchwell MI, Newbold RR, Delclos KB (2006) Lactational transfer of the soy isoflavone, genistein, in Sprague-Dawley rats consuming dietary genistein. Reprod Toxicol 21(3):307\u2013312. doi: 10.1016\/j.reprotox.2005.09.007","journal-title":"Reprod Toxicol"},{"issue":"10","key":"907_CR17","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.jnutbio.2005.03.005","volume":"16","author":"RR Eason","year":"2005","unstructured":"Eason RR, Till SR, Velarde MC, Geng Y, Chatman L Jr, Gu L, Badger TM, Simmen FA, Simmen RC (2005) Uterine phenotype of young adult rats exposed to dietary soy or genistein during development. J Nutr Biochem 16(10):625\u2013632","journal-title":"J Nutr Biochem"},{"issue":"10","key":"907_CR18","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1002\/mnfr.200700217","volume":"51","author":"G Eisenbrand","year":"2007","unstructured":"Eisenbrand G (2007) Isoflavones as phytoestrogens in food supplements and dietary foods for special medical purposes. Opinion of the senate commission on food safety (SKLM) of the German research foundation (DFG)-(shortened version). Mol Nutr Food Res 51(10):1305\u20131312","journal-title":"Mol Nutr Food Res"},{"key":"907_CR19","first-page":"127","volume":"46","author":"KH Fritzemeier","year":"2004","unstructured":"Fritzemeier KH, Hillisch A, Elger W, Kaufmann U, Kollenkirchen U, Kosemund D, Lindenthal B, Muller G, Muhn P, Nubbemeyer R, Peters O, Siebel P, Hegele-Hartung C (2004) Biological effects of ERalpha- and ERbeta-selective estrogens. Ernst Scher Res Found Workshop 46:127\u2013150","journal-title":"Ernst Scher Res Found Workshop"},{"issue":"4","key":"907_CR20","first-page":"302","volume":"9","author":"L Gaete","year":"2010","unstructured":"Gaete L, Tchernitchin AN, Bustamante R, Villena J, Ferrada K, Erazo S, Garcia R, Lemus I (2010) Biological activity of genistein and soy extracts: selective induction of some but not all estrogenic responses in the prepubertal rat uterus. Boletin Litanoamericano y del Carribe de Plantas Medicinales y Arom\u00e1ticas 9(4):302\u2013311","journal-title":"Boletin Litanoamericano y del Carribe de Plantas Medicinales y Arom\u00e1ticas"},{"key":"907_CR21","volume-title":"Histotechnik: Erg\u00e4nzungsheft zu: Laboratoriumsmedizin, ein Lehrbuch f\u00fcr medizinisch-technische Assistentinnen","year":"1989","unstructured":"Hagemann P, Rosenmund K (eds) (1989) Histotechnik: Erg\u00e4nzungsheft zu: Laboratoriumsmedizin, ein Lehrbuch f\u00fcr medizinisch-technische Assistentinnen, 3rd edn. Hirzel, Stuttgart","edition":"3"},{"key":"907_CR22","doi-asserted-by":"crossref","unstructured":"Hertrampf T, Degen GH, Kaid AA, Laudenbach-Leschowsky U, Seibel J, Di Virgilio AL, Diel P (2006) Supporting information to \u201ccombined effects of physical activity, dietary isoflavones and 17beta-estradiol on movement drive, body weight and bone mineral density in ovariectomized female rats\u201d. Planta Med","DOI":"10.1055\/s-2006-931579"},{"issue":"2\u20133","key":"907_CR23","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.toxlet.2009.08.019","volume":"191","author":"T Hertrampf","year":"2009","unstructured":"Hertrampf T, Ledwig C, Kulling S, Molzberger A, Moller FJ, Zierau O, Vollmer G, Moors S, Degen GH, Diel P (2009) Responses of estrogen sensitive tissues in female Wistar rats to pre- and postnatal isoflavone exposure. Toxicol Lett 191(2\u20133):181\u2013188","journal-title":"Toxicol Lett"},{"issue":"12","key":"907_CR24","doi-asserted-by":"crossref","first-page":"2326S","DOI":"10.3945\/jn.110.124230","volume":"140","author":"L Hilakivi-Clarke","year":"2010","unstructured":"Hilakivi-Clarke L, Andrade JE, Helferich W (2010) Is soy consumption good or bad for the breast? J Nutr 140(12):2326S\u20132334S","journal-title":"J Nutr"},{"issue":"7","key":"907_CR25","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1210\/me.2004-0050","volume":"18","author":"A Hillisch","year":"2004","unstructured":"Hillisch A, Peters O, Kosemund D, Muller G, Walter A, Schneider B, Reddersen G, Elger W, Fritzemeier KH (2004) Dissecting physiological roles of estrogen receptor alpha and beta with potent selective ligands from structure-based design. Mol Endocrinol 18(7):1599\u20131609","journal-title":"Mol Endocrinol"},{"issue":"1\u20132","key":"907_CR26","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0378-4274(00)00272-1","volume":"118","author":"KS Kang","year":"2000","unstructured":"Kang KS, Kim HS, Ryu DY, Che JH, Lee YS (2000) Immature uterotrophic assay is more sensitive than ovariectomized uterotrophic assay for the detection of estrogenicity of p-nonylphenol in Sprague-Dawley rats. Toxicol Lett 118(1\u20132):109\u2013115","journal-title":"Toxicol Lett"},{"issue":"2","key":"907_CR27","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0002-8223(99)00051-6","volume":"99","author":"A King","year":"1999","unstructured":"King A, Young G (1999) Characteristics and occurrence of phenolic phytochemicals. J Am Diet Assoc 99(2):213\u2013218","journal-title":"J Am Diet Assoc"},{"issue":"6","key":"907_CR28","doi-asserted-by":"crossref","first-page":"2371","DOI":"10.1210\/en.132.6.2371","volume":"132","author":"WL Kraus","year":"1993","unstructured":"Kraus WL, Katzenellenbogen BS (1993) Regulation of progesterone receptor gene expression and growth in the rat uterus: modulation of estrogen actions by progesterone and sex steroid hormone antagonists. Endocrinology 132(6):2371\u20132379","journal-title":"Endocrinology"},{"issue":"3","key":"907_CR29","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1210\/en.138.3.863","volume":"138","author":"GG Kuiper","year":"1997","unstructured":"Kuiper GG, Carlsson B, Grandien K, Enmark E, Haggblad J, Nilsson S, Gustafsson JA (1997) Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 138(3):863\u2013870","journal-title":"Endocrinology"},{"issue":"10","key":"907_CR30","doi-asserted-by":"crossref","first-page":"4252","DOI":"10.1210\/en.139.10.4252","volume":"139","author":"GG Kuiper","year":"1998","unstructured":"Kuiper GG, Lemmen JG, Carlsson B, Corton JC, Safe SH, van der Saag PT, van der Burg B, Gustafsson JA (1998) Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 139(10):4252\u20134263","journal-title":"Endocrinology"},{"issue":"2","key":"907_CR31","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1210\/jcem-67-2-334","volume":"67","author":"BA Lessey","year":"1988","unstructured":"Lessey BA, Killam AP, Metzger DA, Haney AF, Greene GL, McCarty KS Jr (1988) Immunohistochemical analysis of human uterine estrogen and progesterone receptors throughout the menstrual cycle. J Clin Endocrinol Metab 67(2):334\u2013340","journal-title":"J Clin Endocrinol Metab"},{"issue":"15","key":"907_CR32","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1001\/archinternmed.2011.330","volume":"171","author":"S Levis","year":"2011","unstructured":"Levis S, Strickman-Stein N, Ganjei-Azar P, Xu P, Doerge DR, Krischer J (2011) Soy isoflavones in the prevention of menopausal bone loss and menopausal symptoms: a randomized, double-blind trial. Arch Intern Med 171(15):1363\u20131369","journal-title":"Arch Intern Med"},{"key":"907_CR33","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2741\/s144","volume":"3","author":"MD Molla","year":"2011","unstructured":"Molla MD, Hidalgo-Mora JJ, Soteras MG (2011) Phytotherapy as alternative to hormone replacement therapy. Front Biosci (Schol Ed) 3:191\u2013204","journal-title":"Front Biosci (Schol Ed)"},{"issue":"3\u20135","key":"907_CR34","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.jsbmb.2009.01.016","volume":"113","author":"FJ M\u00f6ller","year":"2009","unstructured":"M\u00f6ller FJ, Zierau O, Hertrampf T, Bliedtner A, Diel P, Vollmer G (2009) Long-term effects of dietary isoflavones on uterine gene expression profiles. J Steroid Biochem Mol Biol 113(3\u20135):296\u2013303","journal-title":"J Steroid Biochem Mol Biol"},{"key":"907_CR35","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.toxlet.2010.03.1117","volume":"196","author":"FJ M\u00f6ller","year":"2010","unstructured":"M\u00f6ller FJ, Diel P, Zierau O, Hertrampf T, Maass J, Vollmer G (2010) Long-term dietary isoflavone exposure enhances estrogen sensitivity of rat uterine responsiveness mediated through estrogen receptor alpha. Toxicol Lett 196:142\u2013153","journal-title":"Toxicol Lett"},{"issue":"7","key":"907_CR36","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/mnfr.200600289","volume":"51","author":"S Moors","year":"2007","unstructured":"Moors S, Blaszkewicz M, Bolt HM, Degen GH (2007) Simultaneous determination of daidzein, equol, genistein and bisphenol A in human urine by a fast and simple method using SPE and GC-MS. Mol Nutr Food Res 51(7):787\u2013798","journal-title":"Mol Nutr Food Res"},{"issue":"3","key":"907_CR37","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1046\/j.1525-1373.2000.22341.x","volume":"223","author":"KP Nephew","year":"2000","unstructured":"Nephew KP, Osborne E, Lubet RA, Grubbs CJ, Khan SA (2000) Effects of oral administration of tamoxifen, toremifene, dehydroepiandrosterone, and vorozole on uterine histomorphology in the rat. Proc Soc Exp Biol Med 223(3):288\u2013294","journal-title":"Proc Soc Exp Biol Med"},{"issue":"11","key":"907_CR38","first-page":"4325","volume":"61","author":"RR Newbold","year":"2001","unstructured":"Newbold RR, Banks EP, Bullock B, Jefferson WN (2001) Uterine adenocarcinoma in mice treated neonatally with genistein. Cancer Res 61(11):4325\u20134328","journal-title":"Cancer Res"},{"issue":"5","key":"907_CR39","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1093\/carcin\/bgh052","volume":"25","author":"TT Nguyen","year":"2004","unstructured":"Nguyen TT, Tran E, Nguyen TH, Do PT, Huynh TH, Huynh H (2004) The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells. Carcinogenesis 25(5):647\u2013659","journal-title":"Carcinogenesis"},{"issue":"3","key":"907_CR40","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/aje\/kwk015","volume":"165","author":"SH Olson","year":"2007","unstructured":"Olson SH, Bandera EV, Orlow I (2007) Variants in estrogen biosynthesis genes, sex steroid hormone levels, and endometrial cancer: a HuGE review. Am J Epidemiol 165(3):235\u2013245","journal-title":"Am J Epidemiol"},{"issue":"12","key":"907_CR41","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1289\/ehp.5949","volume":"111","author":"W Owens","year":"2003","unstructured":"Owens W, Ashby J, Odum J, Onyon L (2003) The OECD program to validate the rat uterotrophic bioassay. Phase 2: dietary phytoestrogen analyses. Environ Health Perspect 111(12):1559\u20131567","journal-title":"Environ Health Perspect"},{"issue":"2","key":"907_CR42","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1093\/toxsci\/56.2.332","volume":"56","author":"AD Papaconstantinou","year":"2000","unstructured":"Papaconstantinou AD, Umbreit TH, Fisher BR, Goering PL, Lappas NT, Brown KM (2000) Bisphenol A-induced increase in uterine weight and alterations in uterine morphology in ovariectomized B6C3F1 mice: role of the estrogen receptor. Toxicol Sci 56(2):332\u2013339","journal-title":"Toxicol Sci"},{"key":"907_CR43","doi-asserted-by":"crossref","unstructured":"Patisaul HB, Jefferson W (2010) The pros and cons of phytoestrogens. Front Neuroendocrinol 31(4):400\u2013419","DOI":"10.1016\/j.yfrne.2010.03.003"},{"issue":"9","key":"907_CR44","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","volume":"29","author":"MW Pfaffl","year":"2001","unstructured":"Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29(9):e45","journal-title":"Nucleic Acids Res"},{"issue":"4","key":"907_CR45","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/PL00007388","volume":"40","author":"MQ Ren","year":"2001","unstructured":"Ren MQ, Kuhn G, Wegner J, Chen J (2001) Isoflavones, substances with multi-biological and clinical properties. Eur J Nutr 40(4):135\u2013146","journal-title":"Eur J Nutr"},{"issue":"3\u20135","key":"907_CR46","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.jsbmb.2007.09.003","volume":"108","author":"S Rice","year":"2008","unstructured":"Rice S, Whitehead SA (2008) Phytoestrogens oestrogen synthesis and breast cancer. J Steroid Biochem Mol Biol 108(3\u20135):186\u2013195","journal-title":"J Steroid Biochem Mol Biol"},{"key":"907_CR47","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1477-7827-4-47","volume":"4","author":"L Sahlin","year":"2006","unstructured":"Sahlin L, Masironi B, Akerberg S, Eriksson H (2006) Tissue- and hormone-dependent progesterone receptor distribution in the rat uterus. Reprod Biol Endocrinol 4:47","journal-title":"Reprod Biol Endocrinol"},{"issue":"12","key":"907_CR48","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1007\/s00204-006-0102-4","volume":"80","author":"S Schmidt","year":"2006","unstructured":"Schmidt S, Degen GH, Seibel J, Hertrampf T, Vollmer G, Diel P (2006) Hormonal activity of combinations of genistein, bisphenol A and 17beta-estradiol in the female Wistar rat. Arch Toxicol 80(12):839\u2013845","journal-title":"Arch Toxicol"},{"issue":"3","key":"907_CR49","doi-asserted-by":"crossref","first-page":"758S","DOI":"10.1093\/jn\/129.3.758S","volume":"129","author":"KD Setchell","year":"1999","unstructured":"Setchell KD, Cassidy A (1999) Dietary isoflavones: biological effects and relevance to human health. J Nutr 129(3):758S\u2013767S","journal-title":"J Nutr"},{"issue":"6","key":"907_CR50","first-page":"527","volume":"25","author":"JE Thigpen","year":"2001","unstructured":"Thigpen JE, Locklear J, Haseman JK, Saunders H, Grant MF, Forsythe DB (2001) Effects of the dietary phytoestrogens daidzein and genistein on the incidence of vulvar carcinomas in 129\/J mice. Cancer Detect Prev 25(6):527\u2013532","journal-title":"Cancer Detect Prev"},{"issue":"5","key":"907_CR51","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1095\/biolreprod59.5.1143","volume":"59","author":"TA Tibbetts","year":"1998","unstructured":"Tibbetts TA, Mendoza-Meneses M, O\u2019Malley BW, Conneely OM (1998) Mutual and intercompartmental regulation of estrogen receptor and progesterone receptor expression in the mouse uterus. Biol Reprod 59(5):1143\u20131152","journal-title":"Biol Reprod"},{"issue":"11","key":"907_CR52","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1016\/S0278-6915(03)00168-6","volume":"41","author":"MG Wade","year":"2003","unstructured":"Wade MG, Lee A, McMahon A, Cooke G, Curran I (2003) The influence of dietary isoflavone on the uterotrophic response in juvenile rats. Food Chem Toxicol 41(11):1517\u20131525","journal-title":"Food Chem Toxicol"},{"issue":"4","key":"907_CR53","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1021\/pr100974w","volume":"10","author":"J Wang","year":"2011","unstructured":"Wang J, Betancourt AM, Mobley JA, Lamartiniere CA (2011) Proteomic discovery of genistein action in the rat mammary gland. J Proteome Res 10(4):1621\u20131631. doi: 10.1021\/pr100974w","journal-title":"J Proteome Res"},{"issue":"11","key":"907_CR54","doi-asserted-by":"crossref","first-page":"5936","DOI":"10.1073\/pnas.97.11.5936","volume":"97","author":"Z Weihua","year":"2000","unstructured":"Weihua Z, Saji S, Makinen S, Cheng G, Jensen EV, Warner M, Gustafsson JA (2000) Estrogen receptor (ER) beta, a modulator of ERalpha in the uterus. Proc Natl Acad Sci USA 97(11):5936\u20135941","journal-title":"Proc Natl Acad Sci USA"},{"issue":"19","key":"907_CR55","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1016\/S0024-3205(02)01483-2","volume":"70","author":"T Wilson","year":"2002","unstructured":"Wilson T, March H, Ban WJ, Hou Y, Adler S, Meyers CY, Winters TA, Maher MA (2002) Antioxidant effects of phyto-and synthetic-estrogens on cupric ion-induced oxidation of human low-density lipoproteins in vitro. Life Sci 70(19):2287\u20132297","journal-title":"Life Sci"}],"container-title":["Archives of Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00204-012-0907-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00204-012-0907-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00204-012-0907-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,22]],"date-time":"2022-01-22T09:03:20Z","timestamp":1642842200000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00204-012-0907-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,19]]},"references-count":55,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["907"],"URL":"https:\/\/doi.org\/10.1007\/s00204-012-0907-2","relation":{},"ISSN":["0340-5761","1432-0738"],"issn-type":[{"value":"0340-5761","type":"print"},{"value":"1432-0738","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,19]]}}}