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All animal experiments were approved by the Ethics Committee Com\u2019Eth (Comit\u00e9 d\u2019Ethique pour l\u2019Exp\u00e9rimentation Animale, Strasbourg, France), and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}