{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T01:50:21Z","timestamp":1792461021451,"version":"4.5.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T00:00:00Z","timestamp":1498176000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch Pharmacol"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1007\/s00210-017-1393-0","type":"journal-article","created":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T05:10:48Z","timestamp":1498194648000},"page":"919-928","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Cytoprotective effects of diallyl trisulfide against valproate-induced hepatotoxicity: new anticonvulsant strategy"],"prefix":"10.1007","volume":"390","author":[{"given":"Ahmed A.","family":"Shaaban","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina S.","family":"El-Agamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,6,23]]},"reference":[{"issue":"2","key":"1393_CR1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s40268-014-0042-z","volume":"14","author":"MA Abdel-Dayem","year":"2014","unstructured":"Abdel-Dayem MA, Elmarakby AA, Abdel-Aziz AA, Pye C, Said SA, El-Mowafy AM (2014) Valproate-induced liver injury: modulation by the omega-3 fatty acid DHA proposes a novel anticonvulsant regimen. Drugs R D 14(2):85\u201394","journal-title":"Drugs R D"},{"issue":"3.2","key":"1393_CR2","first-page":"685","volume":"3","author":"J Akhondian","year":"2015","unstructured":"Akhondian J, Kiani MA, Jafari SA, Beiraghi Toosi M, Mirzaei Najm Abad M, Ahanchian H, Kianifar H (2015) Evaluation of liver enzymes rising in patients treated with sodium valproate (VPA). Int J Ped 3(3.2):685\u2013689","journal-title":"Int J Ped"},{"issue":"4","key":"1393_CR3","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.jhep.2010.11.006","volume":"54","author":"K Begriche","year":"2011","unstructured":"Begriche K, Massart J, Robin MA, Borgne-Sanchez A, Fromenty B (2011) Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. J Hepatol 54(4):773\u2013794","journal-title":"J Hepatol"},{"key":"1393_CR4","doi-asserted-by":"crossref","first-page":"17977","DOI":"10.1073\/pnas.0705710104","volume":"104","author":"GA Benavides","year":"2007","unstructured":"Benavides GA, Squadrito GL, Mills RW, Patel HD, Isbell TS, Patel RP, Darley-Usmar VM, Doeller JE, Kraus DW (2007) Hydrogen sulfide mediates the vasoactivity of garlic. Proc Natl Acad Sci U S A 104:17977\u201317982","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1393_CR5","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1161\/CIRCRESAHA.109.199919","volume":"105","author":"JW Calvert","year":"2009","unstructured":"Calvert JW, Jha S, Gundewar S, Elrod JW, Ramachandran A, Pattillo CB, Kevil CG, Lefer DJ (2009) Hydrogen sulfide mediates cardioprotection through Nrf2 signaling. Circ Res 105:365\u2013374","journal-title":"Circ Res"},{"key":"1393_CR6","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1089\/ars.2009.2882","volume":"12","author":"JW Calvert","year":"2010","unstructured":"Calvert JW, Coetzee WA, Lefer DJ (2010) Novel insights into hydrogen sulfide-mediated cytoprotection. Antioxid Redox Signal 12:1203\u20131217","journal-title":"Antioxid Redox Signal"},{"key":"1393_CR7","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.fct.2006.10.005","volume":"45","author":"KC Chan","year":"2007","unstructured":"Chan KC, Yin MC, Chao WJ (2007) Effect of diallyl trisulfide-rich garlic oil on blood coagulation and plasma activity of anticoagulation factors in rats. Food Chem Toxicol 45:502\u2013507","journal-title":"Food Chem Toxicol"},{"issue":"5","key":"1393_CR8","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/s11596-012-1013-7","volume":"32","author":"H Chen","year":"2012","unstructured":"Chen H, Zhu W, Feng J, Li S (2012) Protective effect of diallyl trisulfide on liver in rats with sepsis and the mechanism. J Huazhong Univ Sci Technolog Med Sci 32(5):657\u2013662","journal-title":"J Huazhong Univ Sci Technolog Med Sci"},{"key":"1393_CR9","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.biopha.2016.01.009","volume":"79","author":"LY Chen","year":"2016","unstructured":"Chen LY, Chen Q, Cheng YF, Jin HH, Kong DS, Zhang F, Wu L, Shao JJ, Zheng SZ (2016a) Diallyl trisulfide attenuates ethanol-induced hepatic steatosis by inhibiting oxidative stress and apoptosis. Biomed Pharmacother 79:35\u201343","journal-title":"Biomed Pharmacother"},{"key":"1393_CR10","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.intimp.2016.04.015","volume":"36","author":"LY Chen","year":"2016","unstructured":"Chen LY, Chen Q, Zhu XJ, Kong DS, Wu L, Shao JJ, Zheng SZ (2016b) Diallyl trisulfide protects against ethanol-induced oxidative stress and apoptosis via a hydrogen sulfide-mediated mechanism. Int Immunopharmacol 36:23\u201330","journal-title":"Int Immunopharmacol"},{"issue":"1","key":"1393_CR11","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/1423-0127-19-50","volume":"19","author":"YH Choi","year":"2012","unstructured":"Choi YH, Park HS (2012) Apoptosis induction of U937 human leukemia cells by diallyl trisulfide induces through generation of reactive oxygen species. J Biomed Sci 19(1):50\u201360","journal-title":"J Biomed Sci"},{"key":"1393_CR12","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/j.bcp.2004.05.031","volume":"68","author":"KS Chun","year":"2004","unstructured":"Chun KS, Surh YJ (2004) Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention. Biochem Pharmacol 68:1089\u20131100","journal-title":"Biochem Pharmacol"},{"key":"1393_CR13","first-page":"S25","volume":"37","author":"CL DeVane","year":"2003","unstructured":"DeVane CL (2003) Pharmacokinetics, drug interactions and tolerability of valproate. Psychopharmacol Bull 37:S25\u2013S42","journal-title":"Psychopharmacol Bull"},{"key":"1393_CR14","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/srep00499","volume":"2","author":"N Dufton","year":"2012","unstructured":"Dufton N, Natividad J, Verdu EF, Wallace JL (2012) Hydrogen sulfide and resolution of acute inflammation: a comparative study utilizing a novel fluorescent probe. Sci Rep 2:499\u2013509","journal-title":"Sci Rep"},{"issue":"14","key":"1393_CR15","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1177\/1535370216643418","volume":"241","author":"DS El-Agamy","year":"2016","unstructured":"El-Agamy DS, Abo-Haded HM, Elkablawy MA (2016) Cardioprotective effects of sitagliptin against doxorubicin-induced cardiotoxicity in rats. Exp Biol Med (Maywood) 241(14):1577\u20131587","journal-title":"Exp Biol Med (Maywood)"},{"issue":"2","key":"1393_CR16","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.3945\/jn.109.109611","volume":"139","author":"T Hosono-Fukao","year":"2009","unstructured":"Hosono-Fukao T, Hosono T, Seki T, Ariga T (2009) Diallyl trisulfide protects rats from carbon tetrachloride-induced liver injury. J Nutr 139(2):2252\u20132256","journal-title":"J Nutr"},{"issue":"3","key":"1393_CR17","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1152\/japplphysiol.00672.2012","volume":"114","author":"YT Huang","year":"2013","unstructured":"Huang YT, Yao CH, Way CL, Lee KW, Tsai CY, Ou HC, Kuo WW (2013) Diallyl trisulfide and diallyl disulfide ameliorate cardiac dysfunction by suppressing apoptotic and enhancing survival pathways in experimental diabetic rats. J Appl Physiol (1985) 114(3):402\u2013410","journal-title":"J Appl Physiol (1985)"},{"key":"1393_CR18","doi-asserted-by":"crossref","first-page":"H801","DOI":"10.1152\/ajpheart.00377.2008","volume":"295","author":"S Jha","year":"2008","unstructured":"Jha S, Calvert JW, Duranski MR, Ramachandran A (2008) Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signalling. Am J Physiol Heart Circ Physiol 295:H801\u2013H806","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"1393_CR19","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.fct.2014.08.009","volume":"73","author":"J Jin","year":"2014","unstructured":"Jin J, Xiong T, Hou X, Sun X, Liao J, Huang Z, Huang M, Zhao Z (2014) Role of Nrf2 activation and NF-\u03baB inhibition in valproic acid induced hepatotoxicity and in diammonium glycyrrhizinate induced protection in mice. Food Chem Toxicol 73:95\u2013104","journal-title":"Food Chem Toxicol"},{"key":"1393_CR20","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1093\/toxsci\/kfq294","volume":"118","author":"TK Kiang","year":"2010","unstructured":"Kiang TK, Teng XW, Karagiozov S, Surendradoss J, Chang TK, Abbott FS (2010) Role of oxidative metabolism in the effect of valproic acid on markers of cell viability, necrosis, and oxidative stress in sandwich-cultured rat hepatocytes. Toxicol Sci 118:501\u2013509","journal-title":"Toxicol Sci"},{"key":"1393_CR21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/ars.2008.2282","volume":"12","author":"Y Kimura","year":"2010","unstructured":"Kimura Y, Goto Y, Kimura H (2010) Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria. Antioxid Redox Signal 12:1\u201313","journal-title":"Antioxid Redox Signal"},{"key":"1393_CR22","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.tox.2015.03.001","volume":"331","author":"T Komulainen","year":"2015","unstructured":"Komulainen T, Lodge T, Hinttala R, Bolszak M, Pietil\u00e4 M, Koivunen P, Hakkola J, Poulton J, Morten KJ, Uusimaa J (2015) Sodium valproate induces mitochondrial respiration dysfunction in HepG2 in vitro cell model. Toxicology 331:47\u201356","journal-title":"Toxicology"},{"key":"1393_CR23","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1080\/10715760701263265","volume":"41","author":"H Laggner","year":"2007","unstructured":"Laggner H, Muellner MK, Schreier S, Sturm B, Hermann M, Exner M, Gmeiner BM, Kapiotis S (2007) Hydrogen sulphide: a novel physiological inhibitor of LDL atherogenic modification by HOCl. Free Radic Res 41:741\u2013747","journal-title":"Free Radic Res"},{"issue":"2","key":"1393_CR24","doi-asserted-by":"crossref","first-page":"487","DOI":"10.3892\/ijmm.2014.2036","volume":"35","author":"HH Lee","year":"2015","unstructured":"Lee HH, Han MH, Hwang HJ, Kim GY, Moon SK, Hyun JW, Kim WJ, Choi YH (2015) Diallyl trisulfide exerts anti-inflammatory effects in lipopolysaccharide-stimulated RAW 264.7 macrophages by suppressing the toll-like receptor 4\/nuclear factor-\u03baB pathway. Int J Mol Med 35(2):487\u2013495","journal-title":"Int J Mol Med"},{"key":"1393_CR25","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ejphar.2005.04.031","volume":"516","author":"CT Liu","year":"2005","unstructured":"Liu CT, Hse H, Li CK, Chen PS, Sheen LY (2005) Effects of garlic oil and diallyl trisulfide on glycemic control in diabetic rats. Eur J Pharmacol 516:165\u2013173","journal-title":"Eur J Pharmacol"},{"issue":"9","key":"1393_CR26","doi-asserted-by":"crossref","first-page":"3472","DOI":"10.1021\/jf060043k","volume":"54","author":"KL Liu","year":"2006","unstructured":"Liu KL, Chen HW, Wang RY, Lei YP, Sheen LY, Lii CK (2006) DATS reduces LPS-induced iNOS expression, NO production, oxidative stress, and NF-kappaB activation in RAW 264.7 macrophages. J Agric Food Chem 54(9):3472\u20133478","journal-title":"J Agric Food Chem"},{"issue":"10","key":"1393_CR27","doi-asserted-by":"crossref","first-page":"669","DOI":"10.2165\/00023210-200216100-00003","volume":"16","author":"W L\u00f6scher","year":"2002","unstructured":"L\u00f6scher W (2002) Basic pharmacology of valproate. A review after 35 years of clinical use for the treatment of epilepsy. CNS Drugs 16(10):669\u2013694","journal-title":"CNS Drugs"},{"key":"1393_CR28","doi-asserted-by":"crossref","first-page":"E1089","DOI":"10.1016\/S0735-1097(10)61090-X","volume":"55","author":"BL Predmore","year":"2010","unstructured":"Predmore BL, Grinsfelder DB, Aragon JP, Elston M, Calvert JW, Lefer DJ (2010) The stable hydrogen sulfide donor, diallyl trisulfide, protects against acute myocardial infarction in mice. J Am Coll Cardiol 55:E1089","journal-title":"J Am Coll Cardiol"},{"key":"1393_CR29","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/j.bbagen.2007.02.004","volume":"1770","author":"K Reyes-Gordillo","year":"2007","unstructured":"Reyes-Gordillo K, Segovia J, Shibayama M, Vergara P, Moreno MG, Muriel P (2007) Curcumin protects against acute liver damage in the rat by inhibiting NFkappaB, proinflammatory cytokines production and oxidative stress. Biochim Biophys Acta 1770:989\u2013996","journal-title":"Biochim Biophys Acta"},{"issue":"11","key":"1393_CR30","first-page":"647","volume":"60","author":"SA Said","year":"2010","unstructured":"Said SA, El-Agamy DS (2010) Prevention of sodium valproate-induced hepatotoxicity by curcumin, rosiglitazone and N-acetylcysteine in rats. Arzneimittelforschung 60(11):647\u2013653","journal-title":"Arzneimittelforschung"},{"issue":"2","key":"1393_CR31","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.tox.2005.10.004","volume":"217","author":"KH Schulpis","year":"2006","unstructured":"Schulpis KH, Lazaropoulou C, Regoutas S, Karikas GA, Margeli A, Tsakiris S, Papassotiriou I (2006) Valproic acid monotherapy induces DNA oxidative damage. Toxicology 217(2):228\u2013232","journal-title":"Toxicology"},{"key":"1393_CR32","first-page":"249","volume":"17","author":"T Seki","year":"2008","unstructured":"Seki T, Hosono T, Hosono-Fukao T, Inada K, Tanaka R, Ogihara J, Ariga T (2008) Anticancer effects of diallyl trisulfide derived from garlic. Asia Pac J Clin Nutr 17:249\u2013252","journal-title":"Asia Pac J Clin Nutr"},{"key":"1393_CR33","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.molcel.2011.10.021","volume":"45","author":"N Sen","year":"2012","unstructured":"Sen N, Paul BD, Gadalla MM, Mustafa AK, Sen T, Xu R, Kim S, Snyder SH (2012) Hydrogen sulfide-linked sulfhydration of NF-kappaB mediates its antiapoptotic actions. Mol Cell 45:13\u201324","journal-title":"Mol Cell"},{"issue":"10","key":"1393_CR34","doi-asserted-by":"crossref","first-page":"3562","DOI":"10.1016\/j.fct.2012.07.056","volume":"50","author":"BB Sokmen","year":"2012","unstructured":"Sokmen BB, Tunali S, Yanardag R (2012) Effects of vitamin U [S-methyl methionine sulphonium chloride] on valproic acid induced liver injury in rats. Food Chem Toxicol 50(10):3562\u20133566","journal-title":"Food Chem Toxicol"},{"issue":"5","key":"1393_CR35","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1177\/0960327114543933","volume":"34","author":"NC Sumedha","year":"2015","unstructured":"Sumedha NC, Miltonprabu S (2015) Diallyl trisulfide ameliorates arsenic-induced hepatotoxicity by abrogation of oxidative stress, inflammation, and apoptosis in rats. Hum Exp Toxicol 34(5):506\u2013525","journal-title":"Hum Exp Toxicol"},{"issue":"2","key":"1393_CR36","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.bionut.2014.01.005","volume":"4","author":"M Suresh","year":"2014","unstructured":"Suresh M, Kumar SNK, Kumar SA, Raman KT, Uma M, Kalaiselvi P (2014) Hesperidin safeguards hepatocytes from valproate-induced liver dysfunction in Sprague-Dawley rats. Biomed Prev Nutr 4(2):209\u2013217","journal-title":"Biomed Prev Nutr"},{"issue":"2","key":"1393_CR37","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1093\/toxsci\/kfi184","volume":"86","author":"V Tong","year":"2005","unstructured":"Tong V, Teng XW, Chang TK, Abbott FS (2005) Valproic acid I: time course of lipid peroxidation biomarkers, liver toxicity, and valproic acid metabolite levels in rats. Toxicol Sci 86(2):427\u2013435","journal-title":"Toxicol Sci"},{"issue":"22","key":"1393_CR38","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0024-3205(00)00548-8","volume":"66","author":"D Vohora","year":"2000","unstructured":"Vohora D, Pal SN, Pillai KK (2000) Thioperamide, a selective histamine H3 receptor antagonist protects against PTZ-induced seizures in mice. Life Sci 66(22):297\u2013301","journal-title":"Life Sci"},{"key":"1393_CR39","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/j.1471-4159.2004.02617.x","volume":"90","author":"M Whiteman","year":"2004","unstructured":"Whiteman M, Armstrong JS, Chu SH, Jia-Ling S, Wong BS, Cheung NS, Halliwell B, Moore PK (2004) The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite \u201cscavenger\u201d? J Neurochem 90:765\u2013768","journal-title":"J Neurochem"},{"key":"1393_CR40","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.bbrc.2004.11.110","volume":"326","author":"M Whiteman","year":"2005","unstructured":"Whiteman M, Cheung NS, Zhu YZ, Chu SH, Siau JL, Wong BS, Armstrong JS, Moore PK (2005) Hydrogen sulphide: a novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain? Biochem Biophys Res Commun 326:794\u2013798","journal-title":"Biochem Biophys Res Commun"},{"key":"1393_CR41","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.bbrc.2006.02.154","volume":"343","author":"M Whiteman","year":"2006","unstructured":"Whiteman M, Li L, Kostetski I, Chu SH, Siau JL, Bhatia M, Moore PK (2006) Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide. Biochem Biophys Res Commun 343:303\u2013310","journal-title":"Biochem Biophys Res Commun"},{"key":"1393_CR42","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1089\/ars.2009.2899","volume":"12","author":"M Whiteman","year":"2010","unstructured":"Whiteman M, Li L, Rose P, Tan CH, Parkinson DB, Moore PK (2010) The effect of hydrogen sulfide donors on lipopolysaccharide induced formation of inflammatory mediators in macrophages. Antioxid Redox Signal 12:1147\u20131154","journal-title":"Antioxid Redox Signal"},{"key":"1393_CR43","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0278-6915(00)00171-X","volume":"39","author":"CC Wu","year":"2001","unstructured":"Wu CC, Sheen LY, Chen HW, Tsai SJ, Li CK (2001) Effects of organosulfur compounds from garlic oil on the antioxidation system in rat liver and red blood cells. Food Chem Toxicol 39:563\u2013569","journal-title":"Food Chem Toxicol"},{"key":"1393_CR44","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1093\/jn\/134.4.724","volume":"134","author":"CC Wu","year":"2004","unstructured":"Wu CC, Li CK, Tsai SJ, Sheen LY (2004) Diallyl trisulfide modulates cell viability and the antioxidation and detoxification systems of rat primary hepatocytes. J Nutr 134:724\u2013728","journal-title":"J Nutr"},{"key":"1393_CR45","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.brainres.2015.04.014","volume":"1614","author":"XH Xu","year":"2015","unstructured":"Xu XH, Li GL, Wang BA, Qin Y, Bai SR, Rong J, Deng T, Li Q (2015) Diallyl trisulfide protects against oxygen glucose deprivation -induced apoptosis by scavenging free radicals via the PI3K\/Akt-mediated Nrf2\/HO-1 signaling pathway in B35 neural cells. Brain Res 1614:38\u201350","journal-title":"Brain Res"},{"key":"1393_CR46","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.tox.2007.07.020","volume":"241","author":"D Yonezawa","year":"2007","unstructured":"Yonezawa D, Sekiguchi F, Miyamoto M, Taniguchi E, Honjo M, Masuko T, Nishikawa H, Kawabata A (2007) A protective role of hydrogen sulfide against oxidative stress in rat gastric mucosal epithelium. Toxicology 241:11\u201318","journal-title":"Toxicology"},{"key":"1393_CR47","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.tox.2008.07.062","volume":"252","author":"T Zeng","year":"2008","unstructured":"Zeng T, Zhang CL, Zhu ZP, Yu LH, Zhao XL, Xie KQ (2008) Diallyl trisulfide (DATS) effectively attenuated oxidative stress-mediated liver injury and hepatic mitochondrial dysfunction in acute ethanol-exposed mice. Toxicology 252:86\u201391","journal-title":"Toxicology"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00210-017-1393-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-017-1393-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-017-1393-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T17:20:52Z","timestamp":1569518452000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00210-017-1393-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,23]]},"references-count":47,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["1393"],"URL":"https:\/\/doi.org\/10.1007\/s00210-017-1393-0","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,23]]}}}