{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T07:35:43Z","timestamp":1788593743959,"version":"build-2803163510"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T00:00:00Z","timestamp":1586217600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T00:00:00Z","timestamp":1586217600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch Pharmacol"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1007\/s00210-020-01854-w","type":"journal-article","created":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T11:04:01Z","timestamp":1586257441000},"page":"1599-1610","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["RETRACTED ARTICLE: Ameliorative effect of nicorandil in ovarian ischemia-reperfusion\u2013induced injury in rats: role of potassium channel"],"prefix":"10.1007","volume":"393","author":[{"given":"Seham Abdel-Wekeel","family":"Abdel-Gaber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Medhat","family":"Atta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara Mohammed Naguib","family":"Abdel-Hafez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6511-1797","authenticated-orcid":false,"given":"Walaa Yehia","family":"Abdelzaher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,4,7]]},"reference":[{"key":"1854_CR1","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.lfs.2018.07.060","volume":"209","author":"SA Abdel-Gaber","year":"2018","unstructured":"Abdel-Gaber SA, Mohammed RK, Refaie MM (2018) Mechanism mediating the protective effect of diacerein in ischemia-reperfusion-induced testicular injury in rats. Life Sci 209:57\u201362","journal-title":"Life Sci"},{"key":"1854_CR2","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1016\/j.pharep.2019.06.006","volume":"71","author":"SA Abdel-Gaber","year":"2019","unstructured":"Abdel-Gaber SA, Geddawy A, Moussa RA (2019) The hepatoprotective effect of sitagliptin against hepatic ischemia reperfusion-induced injury in rats involves Nrf-2\/HO-1 pathway. Pharmacol Rep 71:1044\u20131049. https:\/\/doi.org\/10.1016\/j.pharep.2019.06.006","journal-title":"Pharmacol Rep"},{"key":"1854_CR3","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1111\/bcpt.12078","volume":"113","author":"IT Abdel-Raheem","year":"2013","unstructured":"Abdel-Raheem IT, Taye A, Abouzied MM (2013) Cardioprotective effects of nicorandil, a mitochondrial potassium channel opener against doxorubicin-induced cardiotoxicity in rats. Basic Clin Pharmacol Toxicol 113:158\u2013166. https:\/\/doi.org\/10.1111\/bcpt.12078","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"1854_CR4","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.intimp.2018.07.008","volume":"62","author":"WY Abdelzaher","year":"2018","unstructured":"Abdelzaher WY, Bahaa HA, Toni NDM, Sanad AS (2018) Mechanisms underlying the protective effect of montelukast in prevention of endometrial hyperplasia in female rats. Int Immunopharmacol 62:326\u2013333. https:\/\/doi.org\/10.1016\/j.intimp.2018.07.008","journal-title":"Int Immunopharmacol"},{"key":"1854_CR5","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1523\/jneurosci.4468-06.2007","volume":"27","author":"AY Abramov","year":"2007","unstructured":"Abramov AY, Scorziello A, Duchen MR (2007) Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation. J Neurosci 27:1129\u20131138. https:\/\/doi.org\/10.1523\/jneurosci.4468-06.2007","journal-title":"J Neurosci"},{"key":"1854_CR6","doi-asserted-by":"publisher","first-page":"129","DOI":"10.4103\/1687-4625.195894","volume":"22","author":"SM Ahmed","year":"2016","unstructured":"Ahmed SM, Abdelzaher WY (2016) Zafirlukast alleviates ovarian histological and biochemical alterations induced by ischemia\u2013reperfusion in rats. Kasr Al Ainy Med J 22:129","journal-title":"Kasr Al Ainy Med J"},{"key":"1854_CR7","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1016\/S0735-1097(02)02007-7","volume":"40","author":"M Akao","year":"2002","unstructured":"Akao M, Teshima Y, Marban E (2002) Antiapoptotic effect of nicorandil mediated by mitochondrial atp-sensitive potassium channels in cultured cardiac myocytes. J Am Coll Cardiol 40:803\u2013810","journal-title":"J Am Coll Cardiol"},{"issue":"7","key":"1854_CR8","doi-asserted-by":"publisher","first-page":"721","DOI":"10.3109\/01443615","volume":"35","author":"V Asfour","year":"2015","unstructured":"Asfour V, Varma R, Menon P (2015) Clinical risk factors for ovarian torsion. J Obstet Gynaecol 35(7):721\u2013725. https:\/\/doi.org\/10.3109\/01443615","journal-title":"J Obstet Gynaecol"},{"issue":"11","key":"1854_CR9","doi-asserted-by":"publisher","first-page":"639","DOI":"10.4236\/ojog.2015.511090","volume":"05","author":"D Balsak","year":"2015","unstructured":"Balsak D, Togrul C, Ekinci C et al (2015) Effects of melatonin on ischemia-reperfusion injury in rat ovary: histopathologic and immunohistochemical study. Open J Obstet Gynecol 05(11):639\u2013645","journal-title":"Open J Obstet Gynecol"},{"key":"1854_CR10","doi-asserted-by":"crossref","unstructured":"Bancroft JD, Layton C (2013) The hematoxylins and eosin (7th Edition). In: Suvarna SK, Layton C, Bancroft JD (Eds) Bancroft\u2019s theory and practice of histological techniques, 10. Elsevier, Edinburgh, 173\u2013186","DOI":"10.1016\/B978-0-7020-4226-3.00010-X"},{"key":"1854_CR11","doi-asserted-by":"publisher","first-page":"684","DOI":"10.3906\/sag-1207-108","volume":"43","author":"H BA\u015e","year":"2013","unstructured":"BA\u015e H, KARA \u00d6, Kara M, Pandir D (2013) Protective effect of vardenafil on ischemia\u2013reperfusion injury in rat ovary. Turk J Med Sci 43:684\u2013689","journal-title":"Turk J Med Sci"},{"key":"1854_CR12","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1111\/jog.13846","volume":"45","author":"F Beyazit","year":"2019","unstructured":"Beyazit F, Buyuk B, Turkon H, Elmas S, Uzun M (2019) Adalimumab mitigates ovarian ischemia-reperfusion injury in rats by regulating oxidative stress, apoptosis and resolution of inflammation. J Obstet Gynaecol Res 45:358\u2013367. https:\/\/doi.org\/10.1111\/jog.13846","journal-title":"J Obstet Gynaecol Res"},{"key":"1854_CR13","doi-asserted-by":"publisher","unstructured":"Buege JA, Aust SD (1978) Microsomal lipid peroxidation. Methods Enzymol 52:302\u2013310. https:\/\/doi.org\/10.1016\/s0076-6879(78)52032-6","DOI":"10.1016\/s0076-6879(78)52032-6"},{"key":"1854_CR14","doi-asserted-by":"publisher","first-page":"6435","DOI":"10.1167\/iovs.11-7523","volume":"52","author":"UR Chowdhury","year":"2011","unstructured":"Chowdhury UR, Bahler CK, Hann CR, Chang M, Resch ZT, Romero MF, Fautsch MP (2011) ATP-sensitive potassium (KATP) channel activation decreases intraocular pressure in the anterior chamber of the eye. Invest Ophthalmol Vis Sci 52:6435\u20136442. https:\/\/doi.org\/10.1167\/iovs.11-7523","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1854_CR15","first-page":"148","volume":"II","author":"S C\u00f4t\u00e9","year":"1993","unstructured":"C\u00f4t\u00e9 S (1993) Current protocol for light microscopy immunocytochemistry. Immunohistochemistry II:148\u2013167","journal-title":"Immunohistochemistry"},{"key":"1854_CR16","doi-asserted-by":"publisher","first-page":"219","DOI":"10.17219\/acem\/33250","volume":"25","author":"MC Cure","year":"2016","unstructured":"Cure MC et al (2016) The protective effect of adalimumab on renal injury in a model of abdominal aorta cross-clamping. Adv Clin Exp Med 25:219\u2013226. https:\/\/doi.org\/10.17219\/acem\/33250","journal-title":"Adv Clin Exp Med"},{"key":"1854_CR17","doi-asserted-by":"publisher","unstructured":"Eken MK, Ersoy GS, Kaygusuz EI, Devrano\u011flu B, Tak\u0131r M, \u00c7ilingir \u00d6T, \u00c7evik \u00d6 (2019) Etanercept protects ovarian reserve against ischemia\/reperfusion injury in a rat model. Arch Med Sci. https:\/\/doi.org\/10.5114\/aoms.2017.72406","DOI":"10.5114\/aoms.2017.72406"},{"key":"1854_CR18","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.intimp.2018.09.017","volume":"64","author":"DH El-Kashef","year":"2018","unstructured":"El-Kashef DH (2018) Nicorandil ameliorates pulmonary inflammation and fibrosis in a rat model of silicosis. Int Immunopharmacol 64:289\u2013297. https:\/\/doi.org\/10.1016\/j.intimp.2018.09.017","journal-title":"Int Immunopharmacol"},{"key":"1854_CR19","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.ejphar.2014.12.017","volume":"748","author":"SM Elshazly","year":"2015","unstructured":"Elshazly SM (2015) Ameliorative effect of nicorandil on high fat diet induced non-alcoholic fatty liver disease in rats. Eur J Pharmacol 748:123\u2013132. https:\/\/doi.org\/10.1016\/j.ejphar.2014.12.017","journal-title":"Eur J Pharmacol"},{"key":"1854_CR20","doi-asserted-by":"publisher","first-page":"S76","DOI":"10.4103\/0973-1296.176106","volume":"12","author":"AA El-Sheikh","year":"2016","unstructured":"El-Sheikh AA, Morsy MA, Hamouda AH (2016) Protective mechanisms of thymoquinone on methotrexate-induced intestinal toxicity in rats. Pharmacogn Mag 12:S76\u2013S81. https:\/\/doi.org\/10.4103\/0973-1296.176106","journal-title":"Pharmacogn Mag"},{"key":"1854_CR21","doi-asserted-by":"publisher","first-page":"807","DOI":"10.3892\/br.2015.515","volume":"3","author":"A Eser","year":"2015","unstructured":"Eser A, Hizli D, Haltas H, Namuslu M, Kosus A, Kosus N, Kafali H (2015) Effects of curcumin on ovarian ischemia-reperfusion injury in a rat model. Biomed Rep 3:807\u2013813. https:\/\/doi.org\/10.3892\/br.2015.515","journal-title":"Biomed Rep"},{"key":"1854_CR22","doi-asserted-by":"publisher","first-page":"75339","DOI":"10.18632\/oncotarget.12180","volume":"7","author":"F Finkernagel","year":"2016","unstructured":"Finkernagel F et al (2016) The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization. Oncotarget 7:75339\u201375352. https:\/\/doi.org\/10.18632\/oncotarget.12180","journal-title":"Oncotarget"},{"key":"1854_CR23","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1159\/000235898","volume":"18","author":"L Franco","year":"2009","unstructured":"Franco L, Talamini G (2009) Cross-talk between inducible nitric oxide synthase and cyclooxygenase in Helicobacter-pylori-induced gastritis. Med Princ Pract 18:477\u2013481","journal-title":"Med Princ Pract"},{"key":"1854_CR24","doi-asserted-by":"publisher","first-page":"1673","DOI":"10.1210\/jc.2011-3032","volume":"97","author":"EW Freeman","year":"2012","unstructured":"Freeman EW, Sammel MD, Lin H, Gracia CR (2012) Anti-mullerian hormone as a predictor of time to menopause in late reproductive age women. J Clin Endocrinol Metab 97:1673\u20131680. https:\/\/doi.org\/10.1210\/jc.2011-3032","journal-title":"J Clin Endocrinol Metab"},{"key":"1854_CR25","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/0003-2697(82)90118-X","volume":"126","author":"LC Green","year":"1982","unstructured":"Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR (1982) Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem 126:131\u2013138","journal-title":"Anal Biochem"},{"key":"1854_CR26","doi-asserted-by":"publisher","unstructured":"Hafez HMMZ, Abdel-Ghany H, Zenhom NM, Khalaf MA, Elhussieny M (2017) Nicorandil mitigates renal oxidative damage, apoptotic, and fibrotic changes induced by cyclosporine-A in rats. Egypt J Basic Clin Pharmacol 7:25\u201336. https:\/\/doi.org\/10.32527\/2017\/101423","DOI":"10.32527\/2017\/101423"},{"key":"1854_CR27","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1097\/00005344-200108000-00005","volume":"38","author":"S Horinaka","year":"2001","unstructured":"Horinaka S, Kobayashi N, Higashi T, Hara K, Hara S, Matsuoka H (2001) Nicorandil enhances cardiac endothelial nitric oxide synthase expression via activation of adenosine triphosphate-sensitive K channel in rat. J Cardiovasc Pharmacol 38:200\u2013210","journal-title":"J Cardiovasc Pharmacol"},{"key":"1854_CR28","doi-asserted-by":"publisher","first-page":"143","DOI":"10.4103\/tcmj.tcmj_55_17","volume":"29","author":"C Huang","year":"2017","unstructured":"Huang C, Hong MK, Ding DC (2017) A review of ovary torsion. Ci Ji Yi Xue Za Zhi 29:143\u2013147. https:\/\/doi.org\/10.4103\/tcmj.tcmj_55_17","journal-title":"Ci Ji Yi Xue Za Zhi"},{"key":"1854_CR29","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.ejogrb.2010.02.006","volume":"150","author":"C Huchon","year":"2010","unstructured":"Huchon C, Fauconnier A (2010) Adnexal torsion: a literature review. Eur J Obstet Gynecol Reprod Biol 150:8\u201312. https:\/\/doi.org\/10.1016\/j.ejogrb.2010.02.006","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"1854_CR30","doi-asserted-by":"crossref","unstructured":"Jafari A, Pourrazi H, Nikookheslat S, Baradaran B (2015) Effect of exercise training on Bcl-2 and bax gene expression in the rat heart. Gene Cell Tissue 2(4):e60174","DOI":"10.17795\/gct-32833"},{"key":"1854_CR31","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1016\/j.acthis.2015.07.006","volume":"117","author":"SA Karamese","year":"2015","unstructured":"Karamese SA, Toktay E, Unal D, Selli J, Karamese M, Malkoc I (2015) The protective effects of beta-carotene against ischemia\/reperfusion injury in rat ovarian tissue. Acta Histochem 117:790\u2013797. https:\/\/doi.org\/10.1016\/j.acthis.2015.07.006","journal-title":"Acta Histochem"},{"key":"1854_CR32","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1111\/jog.12658","volume":"41","author":"R Keskin Kurt","year":"2015","unstructured":"Keskin Kurt R et al (2015) Zofenopril attenuates injury induced by ischemia-reperfusion on rat ovary. J Obstet Gynaecol Res 41:926\u2013931. https:\/\/doi.org\/10.1111\/jog.12658","journal-title":"J Obstet Gynaecol Res"},{"key":"1854_CR33","doi-asserted-by":"publisher","first-page":"e115947","DOI":"10.1371\/journal.pone.0115947","volume":"10","author":"D Kumar","year":"2015","unstructured":"Kumar D, Singla SK, Puri V, Puri S (2015) The restrained expression of NF-kB in renal tissue ameliorates folic acid induced acute kidney injury in mice. PLoS One 10:e115947. https:\/\/doi.org\/10.1371\/journal.pone.0115947","journal-title":"PLoS One"},{"key":"1854_CR34","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1111\/j.1432-1033.1974.tb03714.x","volume":"47","author":"S Marklund","year":"1974","unstructured":"Marklund S, Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47:469\u2013474","journal-title":"Eur J Biochem"},{"key":"1854_CR35","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1016\/j.tjog.2018.10.012","volume":"57","author":"K Ozlem","year":"2018","unstructured":"Ozlem K, Birkan Y, Mustafa K, Emin K (2018) Protective effect of Vaccinium myrtillus on ischemia- reperfusion injury in rat ovary. Taiwan J Obstet Gynecol 57:836\u2013841. https:\/\/doi.org\/10.1016\/j.tjog.2018.10.012","journal-title":"Taiwan J Obstet Gynecol"},{"key":"1854_CR36","doi-asserted-by":"publisher","first-page":"376","DOI":"10.5530\/jyp.2017.9.75","volume":"9","author":"S Patel","year":"2017","unstructured":"Patel S, Patel N, Patel V (2017) Anti-fibrotic potential of nicorandil in the treatment of bleomycin induced pulmonary fibrosis. J Young Pharm 9:376\u2013380","journal-title":"J Young Pharm"},{"key":"1854_CR37","doi-asserted-by":"publisher","first-page":"234","DOI":"10.3109\/08941939.2015.1119219","volume":"29","author":"B Prieto-Moure","year":"2016","unstructured":"Prieto-Moure B, Lloris-Cars\u00ed JM, Barrios-Pitarque C, Toledo-Pereyra LH, Lajara-Romance JM, Berda-Antol\u00ed M, Lloris-Cejalvo JM, Cejalvo-Lape\u00f1a D (2016) Pharmacology of ischemia-reperfusion. Translational Research Considerations. J Investig Surg 29:234\u2013249. https:\/\/doi.org\/10.3109\/08941939.2015.1119219","journal-title":"J Investig Surg"},{"key":"1854_CR38","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.intimp.2018.06.037","volume":"62","author":"MMM Refaie","year":"2018","unstructured":"Refaie MMM, El-Hussieny M (2018) Protective effect of pioglitazone on ovarian ischemia reperfusion injury of female rats via modulation of peroxisome proliferator activated receptor gamma and heme-oxygenase 1. Int Immunopharmacol 62:7\u201314. https:\/\/doi.org\/10.1016\/j.intimp.2018.06.037","journal-title":"Int Immunopharmacol"},{"key":"1854_CR39","first-page":"315","volume":"53","author":"Z Sahnoun","year":"1998","unstructured":"Sahnoun Z, Jamoussi K, Zeghal KM (1998) Free radicals and antioxidants: physiology, human pathology and therapeutic aspects (part II). Therapie 53:315\u2013339","journal-title":"Therapie"},{"key":"1854_CR40","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1111\/jog.12858","volume":"42","author":"I Sayar","year":"2016","unstructured":"Sayar I, Bicer S, Gursul C, G\u00fcrb\u00fczel M, Peker K, I\u015fik A (2016) Protective effects of ellagic acid and ozone on rat ovaries with an ischemia\/reperfusion injury. J Obstet Gynaecol Res 42:52\u201358","journal-title":"J Obstet Gynaecol Res"},{"key":"1854_CR41","doi-asserted-by":"publisher","first-page":"444","DOI":"10.4274\/balkanmedj.2016.1386","volume":"34","author":"Z Soyman","year":"2017","unstructured":"Soyman Z, Kelek\u00e7i S, Sal V, \u015eevket O, Bay\u0131nd\u0131r N, Uzun H (2017) Effects of apigenin on experimental ischemia\/reperfusion injury in the rat ovary. Balkan Med J 34:444\u2013449. https:\/\/doi.org\/10.4274\/balkanmedj.2016.1386","journal-title":"Balkan Med J"},{"key":"1854_CR42","doi-asserted-by":"publisher","first-page":"99347","DOI":"10.18632\/oncotarget.19966","volume":"8","author":"Q Su","year":"2017","unstructured":"Su Q, Li L, Zhao J, Sun Y, Yang H (2017) Effects of nicorandil on PI3K\/Akt signaling pathway and its anti-apoptotic mechanisms in coronary microembolization in rats. Oncotarget 8:99347\u201399358. https:\/\/doi.org\/10.18632\/oncotarget.19966","journal-title":"Oncotarget"},{"key":"1854_CR43","doi-asserted-by":"publisher","first-page":"18j","DOI":"10.1016\/0002-9149(89)90200-2","volume":"63","author":"N Taira","year":"1989","unstructured":"Taira N (1989) Nicorandil as a hybrid between nitrates and potassium channel activators. Am J Cardiol 63:18j\u201324j","journal-title":"Am J Cardiol"},{"key":"1854_CR44","doi-asserted-by":"publisher","first-page":"F339","DOI":"10.1152\/ajprenal.00158.2012","volume":"303","author":"Y Tamura","year":"2012","unstructured":"Tamura Y, Tanabe K, Kitagawa W, Uchida S, Schreiner GF, Johnson RJ, Nakagawa T (2012) Nicorandil, a K(atp) channel opener, alleviates chronic renal injury by targeting podocytes and macrophages. Am J Physiol Ren Physiol 303:F339\u2013F349. https:\/\/doi.org\/10.1152\/ajprenal.00158.2012","journal-title":"Am J Physiol Ren Physiol"},{"key":"1854_CR45","first-page":"34","volume":"18","author":"A Tas Hekimoglu","year":"2014","unstructured":"Tas Hekimoglu A, Toprak G, Akkoc H, Evliyaoglu O, Tas T, Kelle I, Colpan L (2014) Protective effect of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) polymerase in distant liver injury induced by renal ischemia-reperfusion in rats. Eur Rev Med Pharmacol Sci 18:34\u201338","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"1854_CR46","doi-asserted-by":"publisher","first-page":"593","DOI":"10.22038\/ijbms.2018.26914.6581","volume":"21","author":"VY Tokgoz","year":"2018","unstructured":"Tokgoz VY, Sipahi M, Keskin O, Guvendi GF, Takir S (2018) Protective effects of vitamin D on ischemia-reperfusion injury of the ovary in a rat model. Iran J Basic Med Sci 21:593\u2013599. https:\/\/doi.org\/10.22038\/ijbms.2018.26914.6581","journal-title":"Iran J Basic Med Sci"},{"key":"1854_CR47","doi-asserted-by":"publisher","first-page":"3415046","DOI":"10.1155\/2016\/3415046","volume":"2016","author":"AA Tuncer","year":"2016","unstructured":"Tuncer AA, Bozkurt MF, Koken T, Dogan N, Pektas MK, Baskin Embleton D (2016) The protective effects of alpha-lipoic acid and coenzyme Q10 combination on ovarian ischemia-reperfusion injury: an experimental study. Adv Med 2016:3415046. https:\/\/doi.org\/10.1155\/2016\/3415046","journal-title":"Adv Med"},{"key":"1854_CR48","doi-asserted-by":"publisher","first-page":"619","DOI":"10.2144\/000112776","volume":"44","author":"HD VanGuilder","year":"2008","unstructured":"VanGuilder HD, Vrana KE, Freeman WM (2008) Twenty-five years of quantitative PCR for gene expression analysis. Biotechniques 44:619\u2013626. https:\/\/doi.org\/10.2144\/000112776","journal-title":"Biotechniques"},{"key":"1854_CR49","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.jneuroim.2018.07.003","volume":"323","author":"I Wimmer","year":"2018","unstructured":"Wimmer I, Zrzavy T, Lassmann H (2018) Neuroinflammatory responses in experimental and human stroke lesions. J Neuroimmunol 323:10\u201318","journal-title":"J Neuroimmunol"},{"key":"1854_CR50","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1093\/humupd\/dmh011","volume":"10","author":"RJ Wu","year":"2004","unstructured":"Wu RJ, Van der Hoek KH, Ryan NK, Norman RJ, Robker RL (2004) Macrophage contributions to ovarian function. Hum Reprod Update 10:119\u2013133. https:\/\/doi.org\/10.1093\/humupd\/dmh011","journal-title":"Hum Reprod Update"},{"key":"1854_CR51","doi-asserted-by":"publisher","first-page":"2320","DOI":"10.1159\/000374035","volume":"35","author":"H Wu","year":"2015","unstructured":"Wu H, Ye M, Yang J, Ding J, Yang J, Dong W, Wang X (2015) Nicorandil protects the heart from ischemia\/reperfusion injury by attenuating endoplasmic reticulum response-induced apoptosis through PI3K\/Akt signaling pathway. Cell Physiol Biochem 35:2320\u20132332. https:\/\/doi.org\/10.1159\/000374035","journal-title":"Cell Physiol Biochem"},{"key":"1854_CR52","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.jss.2009.09.049","volume":"167","author":"H Yamazaki","year":"2011","unstructured":"Yamazaki H et al (2011) The effect of nicorandil on ischemia-reperfusion injury in a porcine total hepatic vascular exclusion model. J Surg Res 167:49\u201355. https:\/\/doi.org\/10.1016\/j.jss.2009.09.049","journal-title":"J Surg Res"},{"key":"1854_CR53","doi-asserted-by":"publisher","first-page":"141","DOI":"10.12659\/msmbr.910974","volume":"24","author":"M Zhang","year":"2018","unstructured":"Zhang M, Zhang H, Liu C, Li X, Ling M, Wang Z, Xing Y (2018) Myocardial protective effects of nicorandil on rats with type 2 diabetic cardiomyopathy. Med Sci Monit Basic Res 24:141\u2013145. https:\/\/doi.org\/10.12659\/msmbr.910974","journal-title":"Med Sci Monit Basic Res"}],"updated-by":[{"DOI":"10.1007\/s00210-026-05091-5","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000}},{"DOI":"10.1007\/s00210-026-05091-5","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"record-id":"71587"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-020-01854-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00210-020-01854-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-020-01854-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T02:03:28Z","timestamp":1778205808000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00210-020-01854-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,7]]},"references-count":53,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["1854"],"URL":"https:\/\/doi.org\/10.1007\/s00210-020-01854-w","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,7]]},"assertion":[{"value":"12 December 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 March 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 April 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 February 2026","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This article has been retracted. Please see the Retraction Notice for more detail:","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s00210-026-05091-5","URL":"https:\/\/doi.org\/10.1007\/s00210-026-05091-5","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The experiments were conducted in accordance with the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health and the protocol was approved by the Faculty of Medicine, Minia University Ethics Committee, for the Care and Use of Laboratory Animals.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}