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Relevant literatures were accessed via Google Scholar, PubMed, Scopus, and Web of Science to give updated information on the phytochemical constituents and pharmacological action of\n                    <jats:italic>Commiphora myrrh<\/jats:italic>\n                    . It has been used traditionally for treating wounds, mouth ulcers, aches, fractures, stomach disorders, microbial infections, and inflammatory diseases. It is used as an antiseptic, astringent, anthelmintic, carminative, emmenagogue, and as an expectorant. Phytochemical studies have shown that it contains terpenoids (monoterpenoids, sesquiterpenoids, and volatile\/essential oil), diterpenoids, triterpenoids, and steroids. Its essential oil has applications in cosmetics, aromatherapy, and perfumery. Research has shown that it exerts various biological activities such as anti-inflammatory, antioxidant, anti-microbial, neuroprotective, anti-diabetic, anti-cancer, analgesic, anti-parasitic, and recently, it was found to work against respiratory infections like COVID-19. With the advancement in drug development, hopefully, its rich phytochemical components can be explored for drug development as an insecticide due to its great anti-parasitic activity. Also, its interactions with drugs can be fully elucidated.\n                  <\/jats:p>\n                  <jats:p>\n                    This review highlights an updated information on the history, distribution, traditional uses, phytochemical components, pharmacology, and various biological activities of\n                    <jats:italic>Commiphora myrrh<\/jats:italic>\n                    .\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Graphical abstract<\/jats:bold>\n                  <\/jats:p>\n                  <jats:p>\n                    Graphical summary of the phytochemical and pharmacological update of\n                    <jats:italic>Commiphora myrrh<\/jats:italic>\n                  <\/jats:p>","DOI":"10.1007\/s00210-022-02325-0","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T03:30:11Z","timestamp":1668742211000},"page":"405-420","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":157,"title":["Commiphora myrrh: a phytochemical and pharmacological update"],"prefix":"10.1007","volume":"396","author":[{"given":"Gaber El-Saber","family":"Batiha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamiaa","family":"Wasef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Oluwafemi","family":"Teibo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hazem M.","family":"Shaheen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Muhammad","family":"Zakariya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Opeyemi Abigail","family":"Akinfe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Titilade Kehinde Ayandeyi","family":"Teibo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayder M.","family":"Al-kuraishy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali I.","family":"Al-Garbee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanasios","family":"Alexiou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marios","family":"Papadakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,18]]},"reference":[{"key":"2325_CR1","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1081\/SL-120003804","volume":"35","author":"MH Abdel-Hay","year":"2002","unstructured":"Abdel-Hay MH, Saleh A, El Ashry ESH et al (2002) Colorimetric determination of crude powdered myrrh, purified myrrh extract, oily fraction, and its different pharmaceutical dosage forms. 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