{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T03:07:10Z","timestamp":1778641630819,"version":"3.51.4"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch Pharmacol"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1007\/s00210-022-02353-w","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T14:29:22Z","timestamp":1669904962000},"page":"693-703","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The modulation of sirtuins by natural compounds in the management of cisplatin-induced nephrotoxicity"],"prefix":"10.1007","volume":"396","author":[{"given":"Simin","family":"Zare","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hedyieh","family":"Karbasforooshan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Wallace","family":"Hayes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1273-5448","authenticated-orcid":false,"given":"Gholamreza","family":"Karimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"key":"2353_CR1","doi-asserted-by":"crossref","unstructured":"Abo El-Magd NF, Ebrahim HA, El-Sherbiny M, Eisa NH (2021) Quinacrine ameliorates cisplatin-induced renal toxicity via modulation of sirtuin-1 pathway. Int J Mol Sci 22:10660","DOI":"10.3390\/ijms221910660"},{"key":"2353_CR2","doi-asserted-by":"publisher","first-page":"e22738","DOI":"10.1002\/jbt.22738","volume":"35","author":"FEM Ali","year":"2021","unstructured":"Ali FEM, Hassanein EHM, El-Bahrawy AH, Omar ZMM, Rashwan EK, Abdel-Wahab BA, Abd-Elhamid TH (2021) Nephroprotective effect of umbelliferone against cisplatin-induced kidney damage is mediated by regulation of NRF2, cytoglobin, SIRT1\/FOXO-3, and NF- kB-p65 signaling pathways. J Biochem Mol Toxicol 35:e22738","journal-title":"J Biochem Mol Toxicol"},{"key":"2353_CR3","doi-asserted-by":"publisher","first-page":"5498054","DOI":"10.1155\/2017\/5498054","volume":"2017","author":"K Anilkumar","year":"2017","unstructured":"Anilkumar K, Reddy GV, Azad R, Yarla NS, Dharmapuri G, Srivastava A, Kamal MA, Pallu R (2017) Evaluation of anti-inflammatory properties of isoorientin isolated from tubers of Pueraria tuberosa. Oxid Med Cell Longev 2017:5498054","journal-title":"Oxid Med Cell Longev"},{"key":"2353_CR4","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1002\/ptr.6565","volume":"34","author":"V Baradaran Rahimi","year":"2020","unstructured":"Baradaran Rahimi V, Ghadiri M, Ramezani M, Askari VR (2020) Antiinflammatory and anti-cancer activities of pomegranate and its constituent, ellagic acid: evidence from cellular, animal, and clinical studies. Phytother Res 34:685\u2013720","journal-title":"Phytother Res"},{"key":"2353_CR5","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1177\/1078155219901305","volume":"26","author":"W Ben Ayed","year":"2020","unstructured":"Ben Ayed W, Ben Said A, Hamdi A, Mokrani A, Masmoudi Y, Toukabri I, Limayem I, Yahyaoui Y (2020) Toxicity, risk factors and management of cisplatin-induced toxicity: a prospective study. J Oncol Pharm Pract 26:1621\u20131629","journal-title":"J Oncol Pharm Pract"},{"key":"2353_CR6","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1097\/FJC.0b013e3181bfaff3","volume":"54","author":"AA Bertelli","year":"2009","unstructured":"Bertelli AA, Das DK (2009) Grapes, wines, resveratrol, and heart health. J Cardiovasc Pharmacol 54:468\u2013476","journal-title":"J Cardiovasc Pharmacol"},{"key":"2353_CR7","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1016\/j.bmcl.2015.01.057","volume":"25","author":"J Bian","year":"2015","unstructured":"Bian J, Xu L, Deng B, Qian X, Fan J, Yang X, Liu F, Xu X, Guo X, Li X, Sun H, You Q, Zhang X (2015) Synthesis and evaluation of (\u00b1)-dunnione and its ortho-quinone analogues as substrates for NAD(P)H:quinone oxidoreductase 1 (NQO1). Bioorg Med Chem Lett 25:1244\u20131248","journal-title":"Bioorg Med Chem Lett"},{"key":"2353_CR8","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1002\/cam4.3728","volume":"10","author":"Y Cao","year":"2021","unstructured":"Cao Y, Li P, Wang H, Li L, Li Q (2021) SIRT3 promotion reduces resistance to cisplatin in lung cancer by modulating the FOXO3\/CDT1 axis. Cancer Med 10:1394\u20131404","journal-title":"Cancer Med"},{"key":"2353_CR9","doi-asserted-by":"crossref","unstructured":"Chien LH, Wu CT, Deng JS, Jiang WP, Huang WC, Huang GJ (2021) Salvianolic Acid C Protects against Cisplatin-Induced Acute Kidney Injury through Attenuation of Inflammation, Oxidative Stress and Apoptotic Effects and Activation of the CaMKK-AMPK-Sirt1-Associated Signaling Pathway in Mouse Models. Antioxidants (Basel) 1010:1620","DOI":"10.3390\/antiox10101620"},{"key":"2353_CR10","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1186\/1472-6882-10-53","volume":"10","author":"WL Chu","year":"2010","unstructured":"Chu WL, Lim YW, Radhakrishnan AK, Lim PE (2010) Protective effect of aqueous extract from Spirulina platensis against cell death induced by free radicals. BMC Complement Altern Med 10:53","journal-title":"BMC Complement Altern Med"},{"key":"2353_CR11","doi-asserted-by":"crossref","unstructured":"Deng JS, Jiang WP, Chen CC, Lee LY, Li PY, Huang WC, Liao JC, Chen HY, Huang SS, Huang GJ (2020) Cordyceps cicadae mycelia ameliorate cisplatin-induced acute kidney injury by suppressing the TLR4\/NF-\u03baB\/MAPK and activating the HO-1\/Nrf2 and Sirt-1\/AMPK pathways in mice. Oxid Med Cell Longev 2020:7912763","DOI":"10.1155\/2020\/7912763"},{"key":"2353_CR12","first-page":"21","volume":"33","author":"NA El-Shitany","year":"2021","unstructured":"El-Shitany NA, Mohammedsaleh ZM, Ali SS, Nasrullah MZ, Bagher AM, Eid BG, Neamatallah T (2021) Activation of sirtuin 1 by ellagic acid ameliorates cisplatin-induced apoptosis, oxidative stress and nephrotoxicity. J Pharm Res Int 33:21\u201332","journal-title":"J Pharm Res Int"},{"key":"2353_CR13","doi-asserted-by":"publisher","first-page":"264","DOI":"10.3389\/fphar.2020.00264","volume":"11","author":"X Fan","year":"2020","unstructured":"Fan X, Wei W, Huang J, Liu X, Ci X (2020a) Isoorientin attenuates cisplatin-induced nephrotoxicity through the inhibition of oxidative stress and apoptosis via activating the SIRT1\/SIRT6\/Nrf-2 pathway. Front Pharmacol 11:264","journal-title":"Front Pharmacol"},{"key":"2353_CR14","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.3389\/fphar.2020.579178","volume":"11","author":"X Fan","year":"2020","unstructured":"Fan X, Wei W, Huang J, Peng L, Ci X (2020b) Daphnetin attenuated cisplatin-induced acute nephrotoxicity with enhancing antitumor activity of cisplatin by upregulating SIRT1\/SIRT6-Nrf2 pathway. Front Pharmacol 11:1877","journal-title":"Front Pharmacol"},{"key":"2353_CR15","doi-asserted-by":"publisher","first-page":"579178","DOI":"10.3389\/fphar.2020.579178","volume":"11","author":"X Fan","year":"2020","unstructured":"Fan X, Wei W, Huang J, Peng L, Ci X (2020c) Daphnetin attenuated cisplatin-induced acute nephrotoxicity with enhancing antitumor activity of cisplatin by upregulating SIRT1\/SIRT6-Nrf2 pathway. Front Pharmacol 11:579178","journal-title":"Front Pharmacol"},{"key":"2353_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jchromb.2013.06.017","volume":"933","author":"H Gao","year":"2013","unstructured":"Gao H, Li Z, Li P, Lin M, Han L, Wang F, Liu J (2013) Determination of Pseudoginsengenin DQ in rat plasma by UPLC-MS\/MS and application of the method in a pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci 933:1\u20137","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"2353_CR17","doi-asserted-by":"publisher","first-page":"112713","DOI":"10.1016\/j.phytochem.2021.112713","volume":"186","author":"CL Gomes","year":"2021","unstructured":"Gomes CL, de Sales VAW, Gomes de Melo C, Ferreira da Silva RM, Vicente Nishimura RH, Rolim LA, RolimNeto PJ (2021) Beta-lapachone: Natural occurrence, physicochemical properties, biological activities, toxicity and synthesis. Phytochemistry 186:112713","journal-title":"Phytochemistry"},{"key":"2353_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jare.2020.01.012","volume":"23","author":"X Hao","year":"2020","unstructured":"Hao X, Pu Z, Cao G, You D, Zhou Y, Deng C, Shi M, Nile SH, Wang Y, Zhou W, Kai G (2020) Tanshinone and salvianolic acid biosynthesis are regulated by SmMYB98 in Salvia miltiorrhiza hairy roots. J Adv Res 23:1\u201312","journal-title":"J Adv Res"},{"key":"2353_CR19","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.fct.2018.03.041","volume":"116","author":"EHM Hassanein","year":"2018","unstructured":"Hassanein EHM, Mohamed WR, Shalkami AS, Khalaf MM, Hemeida RAM (2018) Renoprotective effects of umbelliferone on methotrexate-induced renal injury through regulation of Nrf-2\/Keap-1, P(38)MAPK\/NF-\u03baB, and apoptosis signaling pathways. Food Chem Toxicol 116:152\u2013160","journal-title":"Food Chem Toxicol"},{"key":"2353_CR20","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.bbrc.2012.01.148","volume":"419","author":"YJ Jung","year":"2012","unstructured":"Jung YJ, Lee JE, Lee AS, Kang KP, Lee S, Park SK, Lee SY, Han MK, Kim DH, Kim W (2012) SIRT1 overexpression decreases cisplatin-induced acetylation of NF-\u03baB p65 subunit and cytotoxicity in renal proximal tubule cells. Biochem Biophys Res Commun 419:206\u2013210","journal-title":"Biochem Biophys Res Commun"},{"key":"2353_CR21","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.biopha.2017.10.075","volume":"97","author":"H Karbasforooshan","year":"2018","unstructured":"Karbasforooshan H, Karimi G (2018) The role of SIRT1 in diabetic retinopathy. Biomed Pharmacother 97:190\u2013194","journal-title":"Biomed Pharmacother"},{"key":"2353_CR22","doi-asserted-by":"publisher","first-page":"3209","DOI":"10.1080\/15384101.2020.1843813","volume":"19","author":"H Karbasforooshan","year":"2020","unstructured":"Karbasforooshan H, Hayes AW, Mohammadzadeh N, Zirak MR, Karimi G (2020) The possible role of Sirtuins and microRNAs in hepatocellular carcinoma therapy. Cell Cycle 19:3209\u20133221","journal-title":"Cell Cycle"},{"key":"2353_CR23","doi-asserted-by":"publisher","first-page":"F427","DOI":"10.1152\/ajprenal.00258.2010","volume":"301","author":"DH Kim","year":"2011","unstructured":"Kim DH, Jung YJ, Lee JE, Lee AS, Kang KP, Lee S, Park SK, Han MK, Lee SY, Ramkumar KM, Sung MJ, Kim W (2011) SIRT1 activation by resveratrol ameliorates cisplatin-induced renal injury through deacetylation of p53. Am J Physiol Renal Physiol 301:F427-435","journal-title":"Am J Physiol Renal Physiol"},{"key":"2353_CR24","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.heares.2015.08.017","volume":"333","author":"HJ Kim","year":"2016","unstructured":"Kim HJ, Pandit A, Oh GS, Shen A, Lee SB, Khadka D, Lee S, Shim H, Yang SH, Cho EY, Kwak TH, Choe SK, Park R, So HS (2016) Dunnione ameliorates cisplatin ototoxicity through modulation of NAD(+) metabolism. Hear Res 333:235\u2013246","journal-title":"Hear Res"},{"key":"2353_CR25","doi-asserted-by":"crossref","unstructured":"Kitada M, Koya D (2013) Renal protective effects of resveratrol. Oxid Med Cell Longev 2013:568093","DOI":"10.1155\/2013\/568093"},{"key":"2353_CR26","doi-asserted-by":"publisher","first-page":"2515690x2110688","DOI":"10.1177\/2515690X211068826","volume":"27","author":"T Koltai","year":"2022","unstructured":"Koltai T, Fliegel L (2022) Role of silymarin in cancer treatment: facts, hypotheses, and questions. J Evid Based Integr Med 27:2515690x211068826","journal-title":"J Evid Based Integr Med"},{"key":"2353_CR27","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/j.fct.2013.05.005","volume":"58","author":"HS Lee","year":"2013","unstructured":"Lee HS, Kim BK, Nam Y, Sohn UD, Park ES, Hong SA, Lee JH, Chung YH, Jeong JH (2013) Protective role of phosphatidylcholine against cisplatin-induced renal toxicity and oxidative stress in rats. Food Chem Toxicol 58:388\u2013393","journal-title":"Food Chem Toxicol"},{"key":"2353_CR28","first-page":"178","volume":"8","author":"Y Li","year":"2017","unstructured":"Li Y, Ye Z, Lai W, Rao J, Huang W, Zhang X, Yao Z, Lou T (2017) Activation of sirtuin 3 by silybin attenuates mitochondrial dysfunction in cisplatin-induced acute kidney injury. Front Pharmacol 8:178","journal-title":"Front Pharmacol"},{"key":"2353_CR29","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1002\/jsfa.9221","volume":"99","author":"IC Li","year":"2019","unstructured":"Li IC, Lin S, Tsai YT, Hsu JH, Chen YL, Lin WH, Chen CC (2019a) Cordyceps cicadae mycelia and its active compound HEA exert beneficial effects on blood glucose in type 2 diabetic db\/db mice. J Sci Food Agric 99:606\u2013612","journal-title":"J Sci Food Agric"},{"key":"2353_CR30","doi-asserted-by":"publisher","first-page":"103","DOI":"10.2147\/DDDT.S180543","volume":"13","author":"L Li","year":"2019","unstructured":"Li L, Zhang T, Li C, Xie L, Li N, Hou T, Wang Y, Wang B (2019b) Potential therapeutic effects of Cordyceps cicadae and Paecilomyces cicadae on adenine-induced chronic renal failure in rats and their phytochemical analysis. Drug Des Devel Ther 13:103\u2013117","journal-title":"Drug Des Devel Ther"},{"key":"2353_CR31","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1124\/dmd.109.030734","volume":"38","author":"SC Liang","year":"2010","unstructured":"Liang SC, Ge GB, Liu HX, Zhang YY, Wang LM, Zhang JW, Yin L, Li W, Fang ZZ, Wu JJ, Li GH, Yang L (2010) Identification and characterization of human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of daphnetin. Drug Metab Dispos 38:973\u2013980","journal-title":"Drug Metab Dispos"},{"key":"2353_CR32","doi-asserted-by":"publisher","first-page":"154094","DOI":"10.1016\/j.phymed.2022.154094","volume":"101","author":"S-Y Lin","year":"2022","unstructured":"Lin S-Y, Syu J-P, Lo Y-T, Chau Y-P, Don M-J, Shy H-T, Lai S-M, Kung H-N (2022) Mitochondrial activity is the key to the protective effect of \u03b2-Lapachone, a NAD+ booster, in healthy cells against cisplatin cytotoxicity. Phytomedicine 101:154094","journal-title":"Phytomedicine"},{"key":"2353_CR33","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.ijbiomac.2018.07.101","volume":"119","author":"H Lv","year":"2018","unstructured":"Lv H, Fan X, Wang L, Feng H, Ci X (2018) Daphnetin alleviates lipopolysaccharide\/d-galactosamine-induced acute liver failure via the inhibition of NLRP3, MAPK and NF-\u03baB, and the induction of autophagy. Int J Biol Macromol 119:240\u2013248","journal-title":"Int J Biol Macromol"},{"key":"2353_CR34","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1111\/jphp.12990","volume":"70","author":"P Makhdoumi","year":"2018","unstructured":"Makhdoumi P, Abnous K, Mehri S, Etemad L, Imenshahidi M, Karimi G (2018) Oral deferiprone administration ameliorates cisplatin-induced nephrotoxicity in rats. J Pharm Pharmacol 70:1357\u20131368","journal-title":"J Pharm Pharmacol"},{"key":"2353_CR35","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s40620-017-0392-z","volume":"31","author":"S Manohar","year":"2018","unstructured":"Manohar S, Leung N (2018) Cisplatin nephrotoxicity: a review of the literature. J Nephrol 31:15\u201325","journal-title":"J Nephrol"},{"key":"2353_CR36","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1080\/10715762.2018.1475732","volume":"52","author":"S Nazari Soltan Ahmad","year":"2018","unstructured":"Nazari Soltan Ahmad S, Rashtchizadeh N, Argani H, Roshangar L, Ghorbani Haghjo A, Sanajou D, Panah F, Ashrafi Jigheh Z, Dastmalchi S, Mesgari-Abbasi M (2018) Dunnione protects against experimental cisplatin-induced nephrotoxicity by modulating NQO1 and NAD+ levels. Free Radical Res 52:808\u2013817","journal-title":"Free Radical Res"},{"key":"2353_CR37","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1038\/ki.2013.330","volume":"85","author":"G-S Oh","year":"2014","unstructured":"Oh G-S, Kim H-J, Choi J-H, Shen A, Choe S-K, Karna A, Lee SH, Jo H-J, Yang S-H, Kwak TH (2014a) Pharmacological activation of NQO1 increases NAD+ levels and attenuates cisplatin-mediated acute kidney injury in mice. Kidney Int 85:547\u2013560","journal-title":"Kidney Int"},{"key":"2353_CR38","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1038\/ki.2013.330","volume":"85","author":"GS Oh","year":"2014","unstructured":"Oh GS, Kim HJ, Choi JH, Shen A, Choe SK, Karna A, Lee SH, Jo HJ, Yang SH, Kwak TH, Lee CH, Park R, So HS (2014b) Pharmacological activation of NQO1 increases NAD+ levels and attenuates cisplatin-mediated acute kidney injury in mice. Kidney Int 85:547\u2013560","journal-title":"Kidney Int"},{"key":"2353_CR39","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.semcancer.2019.09.021","volume":"68","author":"DB Oien","year":"2021","unstructured":"Oien DB, Pathoulas CL, Ray U, Thirusangu P, Kalogera E, Shridhar V (2021) Repurposing quinacrine for treatment-refractory cancer. Semin Cancer Biol 68:21\u201330","journal-title":"Semin Cancer Biol"},{"key":"2353_CR40","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1016\/j.plefa.2008.04.008","volume":"78","author":"S Priyamvada","year":"2008","unstructured":"Priyamvada S, Priyadarshini M, Arivarasu NA, Farooq N, Khan S, Khan SA, Khan MW, Yusufi AN (2008) Studies on the protective effect of dietary fish oil on gentamicin-induced nephrotoxicity and oxidative damage in rat kidney. Prostaglandins Leukot Essent Fatty Acids 78:369\u2013381","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"2353_CR41","doi-asserted-by":"crossref","unstructured":"Qi Z, Li Z, Li W, Liu Y, Wang C, Lin H, Liu J, Li P (2018) Pseudoginsengenin DQ exhibits therapeutic effects in cisplatin-induced acute kidney injury via Sirt1\/NF-\u03baB and caspase signaling pathway without compromising its antitumor activity in mice. Molecules 23:3038","DOI":"10.3390\/molecules23113038"},{"key":"2353_CR42","unstructured":"Rodr\u00edguez-Salgueiro S, Ram\u00edrez-Carmenate Z, Gonz\u00e1lez-N\u00fa\u00f1ez L (2017) An update on potential applications of Spirulina sp. and C-phycocyanin to treat kidney diseases. Ann Res Antioxid 2(1)"},{"key":"2353_CR43","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1021\/acs.jafc.7b04565","volume":"66","author":"H Shi","year":"2018","unstructured":"Shi H, Zou J, Zhang T, Che H, Gao X, Wang C, Wang Y, Xue C (2018) Protective effects of DHA-PC against vancomycin-induced nephrotoxicity through the inhibition of oxidative stress and apoptosis in BALB\/c mice. J Agric Food Chem 66:475\u2013484","journal-title":"J Agric Food Chem"},{"key":"2353_CR44","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1039\/C8FO02386G","volume":"10","author":"HH Shi","year":"2019","unstructured":"Shi HH, Wang CC, Guo Y, Xue CH, Zhang TT, Wang YM (2019) DHA-PC protects kidneys against cisplatin-induced toxicity and its underlying mechanisms in mice. Food Funct 10:1571\u20131581","journal-title":"Food Funct"},{"key":"2353_CR45","doi-asserted-by":"publisher","first-page":"9391","DOI":"10.1039\/D1FO02000E","volume":"12","author":"HH Shi","year":"2021","unstructured":"Shi HH, Chen LP, Wang CC, Zhao YC, Xue CH, Wang YM, Mao XZ, Zhang TT (2021) Short-term supplementation of DHA-enriched phospholipids attenuates the nephrotoxicity of cisplatin without compromising its antitumor activity in mice. Food Funct 12:9391\u20139404","journal-title":"Food Funct"},{"key":"2353_CR46","doi-asserted-by":"publisher","first-page":"e22946","DOI":"10.1002\/jbt.22946","volume":"36","author":"FB Tabrizi","year":"2022","unstructured":"Tabrizi FB, Yarmohammadi F, Hayes AW, Karimi G (2022) The modulation of SIRT1 and SIRT3 by natural compounds as a therapeutic target in doxorubicin-induced cardiotoxicity: a review. J Biochem Mol Toxicol 36:e22946","journal-title":"J Biochem Mol Toxicol"},{"key":"2353_CR47","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.phrs.2018.09.022","volume":"137","author":"X Tao","year":"2018","unstructured":"Tao X, Yin L, Xu L, Peng J (2018) Dioscin: a diverse acting natural compound with therapeutic potential in metabolic diseases, cancer, inflammation and infections. Pharmacol Res 137:259\u2013269","journal-title":"Pharmacol Res"},{"key":"2353_CR48","doi-asserted-by":"publisher","first-page":"1741","DOI":"10.1080\/0886022X.2016.1229996","volume":"38","author":"Y Topcu-Tarladacalisir","year":"2016","unstructured":"Topcu-Tarladacalisir Y, Sapmaz-Metin M, Karaca T (2016) Curcumin counteracts cisplatin-induced nephrotoxicity by preventing renal tubular cell apoptosis. Ren Fail 38:1741\u20131748","journal-title":"Ren Fail"},{"key":"2353_CR49","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1177\/0748233713483203","volume":"31","author":"F Tulubas","year":"2015","unstructured":"Tulubas F, Gurel A, Oran M, Topcu B, Caglar V, Uygur E (2015) The protective effects of \u03c9-3 fatty acids on doxorubicin-induced hepatotoxicity and nephrotoxicity in rats. Toxicol Ind Health 31:638\u2013644","journal-title":"Toxicol Ind Health"},{"key":"2353_CR50","doi-asserted-by":"publisher","first-page":"332","DOI":"10.3109\/0886022X.2014.986005","volume":"37","author":"S Ugur","year":"2015","unstructured":"Ugur S, Ulu R, Dogukan A, Gurel A, Yigit IP, Gozel N, Aygen B, Ilhan N (2015) The renoprotective effect of curcumin in cisplatin-induced nephrotoxicity. Ren Fail 37:332\u2013336","journal-title":"Ren Fail"},{"key":"2353_CR51","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s12929-019-0518-9","volume":"26","author":"V Volarevic","year":"2019","unstructured":"Volarevic V, Djokovic B, Jankovic MG, Harrell CR, Fellabaum C, Djonov V, Arsenijevic N (2019) Molecular mechanisms of cisplatin-induced nephrotoxicity: a balance on the knife edge between renoprotection and tumor toxicity. J Biomed Sci 26:25","journal-title":"J Biomed Sci"},{"key":"2353_CR52","doi-asserted-by":"publisher","first-page":"e12727","DOI":"10.1111\/jfbc.12727","volume":"43","author":"X Wang","year":"2019","unstructured":"Wang X, Qin A, Xiao F, Olatunji OJ, Zhang S, Pan D, Han W, Wang D, Ni Y (2019) N(6) -(2-hydroxyethyl)-adenosine from Cordyceps cicadae protects against diabetic kidney disease via alleviation of oxidative stress and inflammation. J Food Biochem 43:e12727","journal-title":"J Food Biochem"},{"key":"2353_CR53","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1186\/s12935-021-02080-x","volume":"21","author":"S Wang","year":"2021","unstructured":"Wang S, Cai Y, Feng Q, Gao J, Teng B (2021) Pseudoginsengenin DQ exerts antitumour activity against hypopharyngeal cancer cells by targeting the HIF-1\u03b1-GLUT1 pathway. Cancer Cell Int 21:382","journal-title":"Cancer Cell Int"},{"key":"2353_CR54","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.lfs.2016.09.012","volume":"166","author":"P Wu","year":"2016","unstructured":"Wu P, Han N, Yu H, Wang L, Li X, Dong Z, Fu W, Yorinaka H, Cho K, Wu W, Liu X, Yang M, Guo DA, Yin J, Jiang B (2016) Amelioration of salvianolic acid C on aortic structure in apolipoprotein E-deficient mice treated with angiotension II. Life Sci 166:75\u201381","journal-title":"Life Sci"},{"key":"2353_CR55","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.ejphar.2011.08.019","volume":"670","author":"R Yao","year":"2011","unstructured":"Yao R, Fu Y, Li S, Tu L, Zeng X, Kuang N (2011) Regulatory effect of daphnetin, a coumarin extracted from Daphne odora, on the balance of Treg and Th17 in collagen-induced arthritis. Eur J Pharmacol 670:286\u2013294","journal-title":"Eur J Pharmacol"},{"key":"2353_CR56","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.taap.2012.09.022","volume":"265","author":"L Yuan","year":"2012","unstructured":"Yuan L, Wang J, Xiao H, Xiao C, Wang Y, Liu X (2012) Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of PI3K\/Akt signaling pathway in HepG2 cancer cells. Toxicol Appl Pharmacol 265:83\u201392","journal-title":"Toxicol Appl Pharmacol"},{"key":"2353_CR57","first-page":"54","volume":"6","author":"MM Zakaria","year":"2019","unstructured":"Zakaria MM, El-Tantawy FMM, Khater SM, Derbala SA, Farag VME-M, Abdel-Aziz A-AF (2019) Protective and curative role of Spirulina platensis extracts on cisplatin induce acute kidney injury in rats. Egypt J Basic Appl Sci 6:54\u201367","journal-title":"Egypt J Basic Appl Sci"},{"key":"2353_CR58","doi-asserted-by":"publisher","first-page":"2512","DOI":"10.1111\/bph.13862","volume":"174","author":"Y Zhang","year":"2017","unstructured":"Zhang Y, Tao X, Yin L, Xu L, Xu Y, Qi Y, Han X, Song S, Zhao Y, Lin Y (2017a) Protective effects of dioscin against cisplatin-induced nephrotoxicity via the microRNA-34a\/sirtuin 1 signalling pathway. Br J Pharmacol 174:2512\u20132527","journal-title":"Br J Pharmacol"},{"key":"2353_CR59","doi-asserted-by":"publisher","first-page":"2512","DOI":"10.1111\/bph.13862","volume":"174","author":"Y Zhang","year":"2017","unstructured":"Zhang Y, Tao X, Yin L, Xu L, Xu Y, Qi Y, Han X, Song S, Zhao Y, Lin Y, Liu K, Peng J (2017b) Protective effects of dioscin against cisplatin-induced nephrotoxicity via the microRNA-34a\/sirtuin 1 signalling pathway. Br J Pharmacol 174:2512\u20132527","journal-title":"Br J Pharmacol"},{"key":"2353_CR60","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1093\/humupd\/1.4.324","volume":"1","author":"J Zipper","year":"1995","unstructured":"Zipper J, Dabancens A, Guerrero A, Trujillo V (1995) Quinacrine revised. Hum Reprod Update 1:324\u2013342","journal-title":"Hum Reprod Update"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-022-02353-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00210-022-02353-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-022-02353-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T05:03:28Z","timestamp":1679893408000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00210-022-02353-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":60,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["2353"],"URL":"https:\/\/doi.org\/10.1007\/s00210-022-02353-w","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,1]]},"assertion":[{"value":"28 August 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 November 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 December 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}