{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:25:51Z","timestamp":1793139951021,"version":"4.5.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82160148"],"award-info":[{"award-number":["82160148"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch Pharmacol"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1007\/s00210-024-03183-8","type":"journal-article","created":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T04:00:58Z","timestamp":1717214458000},"page":"8691-8706","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Network pharmacological analysis and experimental study of melatonin in chronic prostatitis\/chronic pelvic pain syndrome"],"prefix":"10.1007","volume":"397","author":[{"given":"Yanan","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongfeng","family":"Lao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyu","family":"You","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangliang","family":"Qing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4919-8164","authenticated-orcid":false,"given":"Zhilong","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,1]]},"reference":[{"issue":"2","key":"3183_CR1","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/j.jhep.2014.04.012","volume":"61","author":"V Arroyo","year":"2014","unstructured":"Arroyo V, Garcia-Martinez R, Salvatella X (2014) Human serum albumin, systemic inflammation, and cirrhosis. J Hepatol 61(2):396\u2013407. https:\/\/doi.org\/10.1016\/j.jhep.2014.04.012","journal-title":"J Hepatol"},{"issue":"4","key":"3183_CR2","doi-asserted-by":"publisher","first-page":"1633","DOI":"10.1002\/bab.2233","volume":"69","author":"M Asadi","year":"2022","unstructured":"Asadi M, Taghizadeh S, Kaviani E, Vakili O, Taheri-Anganeh M, Tahamtan M, Savardashtaki A (2022) Caspase-3: structure, function, and biotechnological aspects. Biotechnol Appl Biochem 69(4):1633\u20131645. https:\/\/doi.org\/10.1002\/bab.2233","journal-title":"Biotechnol Appl Biochem"},{"issue":"12","key":"3183_CR3","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1093\/molehr\/4.12.1099","volume":"4","author":"A Basu","year":"1998","unstructured":"Basu A, Haldar S (1998) The relationship between BcI2, Bax and p53: consequences for cell cycle progression and cell death. Mol Hum Reprod 4(12):1099\u20131109. https:\/\/doi.org\/10.1093\/molehr\/4.12.1099","journal-title":"Mol Hum Reprod"},{"key":"3183_CR4","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/512926","volume":"2012","author":"SE Byeon","year":"2012","unstructured":"Byeon SE, Yi YS, Oh J, Yoo BC, Hong S, Cho JY (2012) The role of Src kinase in macrophage-mediated inflammatory responses. Mediators Inflamm 2012:512926. https:\/\/doi.org\/10.1155\/2012\/512926","journal-title":"Mediators Inflamm"},{"issue":"10","key":"3183_CR5","doi-asserted-by":"publisher","first-page":"1812","DOI":"10.1111\/febs.13627","volume":"283","author":"T Cartwright","year":"2016","unstructured":"Cartwright T, Perkins ND, C LW, (2016) NFKB1: a suppressor of inflammation, ageing and cancer. FEBS J 283(10):1812\u20131822. https:\/\/doi.org\/10.1111\/febs.13627","journal-title":"FEBS J"},{"issue":"1","key":"3183_CR6","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1007\/s00005-021-00628-3","volume":"69","author":"L Chen","year":"2021","unstructured":"Chen L, Zhang M, Liang C (2021a) Chronic prostatitis and pelvic pain syndrome: another autoimmune disease? Arch Immunol Ther Exp (Warsz) 69(1):24. https:\/\/doi.org\/10.1007\/s00005-021-00628-3","journal-title":"Arch Immunol Ther Exp (Warsz)"},{"issue":"10","key":"3183_CR7","doi-asserted-by":"publisher","DOI":"10.1111\/and.14206","volume":"53","author":"Q Chen","year":"2021","unstructured":"Chen Q, Feng J, Liu Z, An D, Li Y, Zhou S, Weng Z (2021b) Research trends of prostatitis over past 20 years: a bibliometric analysis. Andrologia 53(10):e14206. https:\/\/doi.org\/10.1111\/and.14206","journal-title":"Andrologia"},{"issue":"15","key":"3183_CR8","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1002\/pros.24214","volume":"81","author":"J Chen","year":"2021","unstructured":"Chen J, Zhang LG, Du HX, Zhan CS, Liu Y, Zhang M, Chen XG, Wen LP, Zhang L, Liang CZ (2021c) Melatonin attenuates prostatic inflammation and pelvic pain via Sirt1-dependent inhibition of the NLRP3 inflammasome in an EAP mouse model. Prostate 81(15):1179\u20131190. https:\/\/doi.org\/10.1002\/pros.24214","journal-title":"Prostate"},{"key":"3183_CR9","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.bioorg.2019.01.017","volume":"86","author":"A Elkamhawy","year":"2019","unstructured":"Elkamhawy A, Hassan AHE, Paik S, Sup Lee Y, Lee HH, Shin JS, Lee KT, Roh EJ (2019) EGFR inhibitors from cancer to inflammation: Discovery of 4-fluoro-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide as a novel anti-inflammatory EGFR inhibitor. Bioorg Chem 86:112\u2013118. https:\/\/doi.org\/10.1016\/j.bioorg.2019.01.017","journal-title":"Bioorg Chem"},{"issue":"5","key":"3183_CR10","doi-asserted-by":"publisher","first-page":"406","DOI":"10.22037\/uj.v18i.6761","volume":"19","author":"A Fotovat","year":"2022","unstructured":"Fotovat A, Samadzadeh B, Ayati M, Nowroozi MR, Momeni SA, Yavari S, Nasseri A, Sharifi L (2022) The effect of melatonin on improving the benign prostatic hyperplasia urinary symptoms, a randomized clinical trial. Urol J 19(5):406\u2013411. https:\/\/doi.org\/10.22037\/uj.v18i.6761","journal-title":"Urol J"},{"issue":"12","key":"3183_CR11","doi-asserted-by":"publisher","first-page":"3093","DOI":"10.1111\/jsm.12696","volume":"11","author":"J Gao","year":"2014","unstructured":"Gao J, Xu C, Liang C, Su P, Peng Z, Shi K, Tang D, Gao P, Lu Z, Liu J, Xia L, Yang J, Hao Z, Zhou J, Zhang X (2014) Relationships between intravaginal ejaculatory latency time and national institutes of health-chronic prostatitis symptom index in the four types of premature ejaculation syndromes: a large observational study in China. J Sex Med 11(12):3093\u20133101. https:\/\/doi.org\/10.1111\/jsm.12696","journal-title":"J Sex Med"},{"issue":"4","key":"3183_CR12","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1002\/cbin.10920","volume":"42","author":"MG Gobbo","year":"2018","unstructured":"Gobbo MG, Tamarindo GH, Ribeiro DL, de Campos SGP, Taboga SR, Goes RM (2018) Pathological lesions and global DNA methylation in rat prostate under streptozotocin-induced diabetes and melatonin supplementation. Cell Biol Int 42(4):470\u2013487. https:\/\/doi.org\/10.1002\/cbin.10920","journal-title":"Cell Biol Int"},{"key":"3183_CR13","doi-asserted-by":"publisher","unstructured":"Hardeland R (2019) Aging, melatonin, and the pro- and anti-inflammatory networks. Int J Mol Sci 20 (5). https:\/\/doi.org\/10.3390\/ijms20051223","DOI":"10.3390\/ijms20051223"},{"key":"3183_CR14","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/j.biopha.2018.06.139","volume":"106","author":"AU Ihsan","year":"2018","unstructured":"Ihsan AU, Khan FU, Khongorzul P, Ahmad KA, Naveed M, Yasmeen S, Cao Y, Taleb A, Maiti R, Akhter F, Liao X, Li X, Cheng Y, Khan HU, Alam K, Zhou X (2018) Role of oxidative stress in pathology of chronic prostatitis\/chronic pelvic pain syndrome and male infertility and antioxidants function in ameliorating oxidative stress. Biomed Pharmacother 106:714\u2013723. https:\/\/doi.org\/10.1016\/j.biopha.2018.06.139","journal-title":"Biomed Pharmacother"},{"issue":"13","key":"3183_CR15","doi-asserted-by":"publisher","first-page":"1498","DOI":"10.1002\/pros.23880","volume":"79","author":"SH Jeon","year":"2019","unstructured":"Jeon SH, Zhu GQ, Kwon EB, Lee KW, Cho HJ, Ha US, Hong SH, Lee JY, Bae WJ, Kim SW (2019) Extracorporeal shock wave therapy decreases COX-2 by inhibiting TLR4-NFkappaB pathway in a prostatitis rat model. Prostate 79(13):1498\u20131504. https:\/\/doi.org\/10.1002\/pros.23880","journal-title":"Prostate"},{"issue":"3","key":"3183_CR16","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.23102","volume":"34","author":"Y Jiang","year":"2020","unstructured":"Jiang Y, Fang B, Xu B, Chen L (2020) The RAS-PI3K-AKT-NF-kappaB pathway transcriptionally regulates the expression of BCL2 family and IAP family genes and inhibits apoptosis in fibrous epulis. J Clin Lab Anal 34(3):e23102. https:\/\/doi.org\/10.1002\/jcla.23102","journal-title":"J Clin Lab Anal"},{"key":"3183_CR17","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1016\/j.biopha.2017.08.016","volume":"94","author":"FU Khan","year":"2017","unstructured":"Khan FU, Ihsan AU, Khan HU, Jana R, Wazir J, Khongorzul P, Waqar M, Zhou X (2017) Comprehensive overview of prostatitis. Biomed Pharmacother 94:1064\u20131076. https:\/\/doi.org\/10.1016\/j.biopha.2017.08.016","journal-title":"Biomed Pharmacother"},{"issue":"7","key":"3183_CR18","doi-asserted-by":"publisher","first-page":"2409","DOI":"10.1053\/j.gastro.2021.02.040","volume":"160","author":"S Mahurkar-Joshi","year":"2021","unstructured":"Mahurkar-Joshi S, Rankin CR, Videlock EJ, Soroosh A, Verma A, Khandadash A, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L (2021) The colonic mucosal microRNAs, microRNA-219a-5p, and microRNA-338\u20133p are downregulated in irritable bowel syndrome and are associated with barrier function and MAPK signaling. Gastroenterology 160(7):2409-2422 e2419. https:\/\/doi.org\/10.1053\/j.gastro.2021.02.040","journal-title":"Gastroenterology"},{"issue":"1","key":"3183_CR19","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1111\/andr.12647","volume":"8","author":"R Mandar","year":"2020","unstructured":"Mandar R, Korrovits P, Rahu K, Rahu M, Sibul EL, Mehik A, Punab M (2020) Dramatically deteriorated quality of life in men with prostatitis-like symptoms. Andrology 8(1):101\u2013109. https:\/\/doi.org\/10.1111\/andr.12647","journal-title":"Andrology"},{"key":"3183_CR20","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/2789_2006_020","volume":"1","author":"SJ McPherson","year":"2006","unstructured":"McPherson SJ, Ellem SJ, Patchev V, Fritzemeier KH, Risbridger GP (2006) The role of Eralpha and ERbeta in the prostate: insights from genetic models and isoform-selective ligands. Ernst Schering Found Symp Proc 1:131\u2013147. https:\/\/doi.org\/10.1007\/2789_2006_020","journal-title":"Ernst Schering Found Symp Proc"},{"issue":"11","key":"3183_CR21","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1002\/pros.23536","volume":"78","author":"LQ Meng","year":"2018","unstructured":"Meng LQ, Yang FY, Wang MS, Shi BK, Chen DX, Chen D, Zhou Q, He QB, Ma LX, Cheng WL, Xing NZ (2018) Quercetin protects against chronic prostatitis in rat model through NF-kappaB and MAPK signaling pathways. Prostate 78(11):790\u2013800. https:\/\/doi.org\/10.1002\/pros.23536","journal-title":"Prostate"},{"issue":"4","key":"3183_CR22","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1002\/bit.260400403","volume":"40","author":"CH Park","year":"1992","unstructured":"Park CH, Martinez BC (1992) Enhanced release of rosmarinic acid from Coleus blumei permeabilized by dimethyl sulfoxide (DMSO) while preserving cell viability and growth. Biotechnol Bioeng 40(4):459\u2013464. https:\/\/doi.org\/10.1002\/bit.260400403","journal-title":"Biotechnol Bioeng"},{"issue":"2","key":"3183_CR23","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.canlet.2011.08.001","volume":"312","author":"KR Park","year":"2011","unstructured":"Park KR, Nam D, Yun HM, Lee SG, Jang HJ, Sethi G, Cho SK, Ahn KS (2011) Beta-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K\/AKT\/mTOR\/S6K1 pathways and ROS-mediated MAPKs activation. Cancer Lett 312(2):178\u2013188. https:\/\/doi.org\/10.1016\/j.canlet.2011.08.001","journal-title":"Cancer Lett"},{"key":"3183_CR24","doi-asserted-by":"publisher","unstructured":"Pinzi L, Rastelli G (2019) Molecular docking: shifting paradigms in drug discovery. Int J Mol Sci 20 (18). https:\/\/doi.org\/10.3390\/ijms20184331","DOI":"10.3390\/ijms20184331"},{"key":"3183_CR25","doi-asserted-by":"publisher","unstructured":"Sandhu J, Tu HYV (2017) Recent advances in managing chronic prostatitis\/chronic pelvic pain syndrome. F1000Res 6. https:\/\/doi.org\/10.12688\/f1000research.10558.1","DOI":"10.12688\/f1000research.10558.1"},{"issue":"2","key":"3183_CR26","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/s0955-0674(00)00194-0","volume":"13","author":"GL Semenza","year":"2001","unstructured":"Semenza GL (2001) HIF-1 and mechanisms of hypoxia sensing. Curr Opin Cell Biol 13(2):167\u2013171. https:\/\/doi.org\/10.1016\/s0955-0674(00)00194-0","journal-title":"Curr Opin Cell Biol"},{"key":"3183_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2021.101954","volume":"41","author":"J Shi","year":"2021","unstructured":"Shi J, Yu T, Song K, Du S, He S, Hu X, Li X, Li H, Dong S, Zhang Y, Xie Z, Li C, Yu J (2021) Dexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a\/HO-1 signaling pathway. Redox Biol 41:101954. https:\/\/doi.org\/10.1016\/j.redox.2021.101954","journal-title":"Redox Biol"},{"issue":"4","key":"3183_CR28","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1089\/ars.2010.3405","volume":"14","author":"P Storz","year":"2011","unstructured":"Storz P (2011) Forkhead homeobox type O transcription factors in the responses to oxidative stress. Antioxid Redox Signal 14(4):593\u2013605. https:\/\/doi.org\/10.1089\/ars.2010.3405","journal-title":"Antioxid Redox Signal"},{"issue":"3","key":"3183_CR29","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1038\/nrurol.2010.4","volume":"7","author":"AC Strauss","year":"2010","unstructured":"Strauss AC, Dimitrakov JD (2010) New treatments for chronic prostatitis\/chronic pelvic pain syndrome. Nat Rev Urol 7(3):127\u2013135. https:\/\/doi.org\/10.1038\/nrurol.2010.4","journal-title":"Nat Rev Urol"},{"key":"3183_CR30","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.bcp.2017.02.015","volume":"131","author":"SV Vartak","year":"2017","unstructured":"Vartak SV, Iyer D, Santhoshkumar TR, Sharma S, Mishra A, Goldsmith G, Srivastava M, Srivastava S, Karki SS, Surolia A, Choudhary B, Raghavan SC (2017) Novel BCL2 inhibitor, Disarib induces apoptosis by disruption of BCL2-BAK interaction. Biochem Pharmacol 131:16\u201328. https:\/\/doi.org\/10.1016\/j.bcp.2017.02.015","journal-title":"Biochem Pharmacol"},{"issue":"3","key":"3183_CR31","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.4049\/jimmunol.1601515","volume":"198","author":"E Vergadi","year":"2017","unstructured":"Vergadi E, Ieronymaki E, Lyroni K, Vaporidi K, Tsatsanis C (2017) Akt signaling pathway in macrophage activation and M1\/M2 polarization. J Immunol 198(3):1006\u20131014. https:\/\/doi.org\/10.4049\/jimmunol.1601515","journal-title":"J Immunol"},{"issue":"2","key":"3183_CR32","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1007\/s11064-021-03449-0","volume":"47","author":"Y Wang","year":"2022","unstructured":"Wang Y, Yang R, Yan F, Jin Y, Liu X, Wang T (2022) Medicarpin protects cerebral microvascular endothelial cells against oxygen-glucose deprivation\/reoxygenation-induced injury via the PI3K\/Akt\/FoxO pathway: a study of network pharmacology analysis and experimental validation. Neurochem Res 47(2):347\u2013357. https:\/\/doi.org\/10.1007\/s11064-021-03449-0","journal-title":"Neurochem Res"},{"issue":"6","key":"3183_CR33","doi-asserted-by":"publisher","first-page":"4995","DOI":"10.3892\/ol.2017.6070","volume":"13","author":"C Yao","year":"2017","unstructured":"Yao C, Li G, Cai M, Qian Y, Wang L, Xiao L, Thaiss F, Shi B (2017) Prostate cancer downregulated SIRP-alpha modulates apoptosis and proliferation through p38-MAPK\/NF-kappaB\/COX-2 signaling. Oncol Lett 13(6):4995\u20135001. https:\/\/doi.org\/10.3892\/ol.2017.6070","journal-title":"Oncol Lett"},{"issue":"5","key":"3183_CR34","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0096824","volume":"9","author":"F Zeng","year":"2014","unstructured":"Zeng F, Chen H, Yang J, Wang L, Cui Y, Guan X, Wang Z, Niu J, Zu X, Qi L, Zhang X, Tang Z, Liu L (2014) Development and validation of an animal model of prostate inflammation-induced chronic pelvic pain: evaluating from inflammation of the prostate to pain behavioral modifications. PLoS ONE 9(5):e96824. https:\/\/doi.org\/10.1371\/journal.pone.0096824","journal-title":"PLoS ONE"},{"key":"3183_CR35","doi-asserted-by":"publisher","DOI":"10.1007\/s11030-024-10822-y","author":"X Zha","year":"2024","unstructured":"Zha X, Ji R, Li Y, Cao R, Zhou S (2024) Network pharmacology, molecular docking, and molecular dynamics simulation analysis reveal the molecular mechanism of halociline against gastric cancer. Mol Divers. https:\/\/doi.org\/10.1007\/s11030-024-10822-y","journal-title":"Mol Divers"},{"issue":"1","key":"3183_CR36","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1002\/jcp.22722","volume":"227","author":"Y Zhang","year":"2012","unstructured":"Zhang Y, Wang L, Zhang M, Jin M, Bai C, Wang X (2012) Potential mechanism of interleukin-8 production from lung cancer cells: an involvement of EGF-EGFR-PI3K-Akt-Erk pathway. J Cell Physiol 227(1):35\u201343. https:\/\/doi.org\/10.1002\/jcp.22722","journal-title":"J Cell Physiol"},{"issue":"4","key":"3183_CR37","doi-asserted-by":"publisher","first-page":"155798831986538","DOI":"10.1177\/1557988319865380","volume":"13","author":"J Zhang","year":"2019","unstructured":"Zhang J, Zhang X, Cai Z, Li N, Li H (2019) The lifetime risk and prognosis of chronic prostatitis\/chronic pelvic pain syndrome in the middle-aged Chinese males. Am J Mens Health 13(4):1557988319865380. https:\/\/doi.org\/10.1177\/1557988319865380","journal-title":"Am J Mens Health"},{"issue":"16","key":"3183_CR38","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1002\/pros.24065","volume":"80","author":"LG Zhang","year":"2020","unstructured":"Zhang LG, Yu ZQ, Yang C, Chen J, Zhan CS, Chen XG, Zhang L, Hao ZY, Liang CZ (2020) Effect of Eriocalyxin B on prostatic inflammation and pelvic pain in a mouse model of experimental autoimmune prostatitis. Prostate 80(16):1394\u20131404. https:\/\/doi.org\/10.1002\/pros.24065","journal-title":"Prostate"},{"issue":"4","key":"3183_CR39","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1007\/s00011-022-01544-8","volume":"71","author":"Y Zhou","year":"2022","unstructured":"Zhou Y, Wang JH, Han JP, Feng JY, Guo K, Du F, Chen WB, Li YZ (2022) Dihydroartemisinin ameliorates chronic nonbacterial prostatitis and epithelial cellular inflammation by blocking the E2F7\/HIF1alpha pathway. Inflamm Res 71(4):449\u2013460. https:\/\/doi.org\/10.1007\/s00011-022-01544-8","journal-title":"Inflamm Res"},{"key":"3183_CR40","doi-asserted-by":"publisher","first-page":"3473796","DOI":"10.1155\/2017\/3473796","volume":"2017","author":"D Zhu","year":"2017","unstructured":"Zhu D, Dou X, Tang L, Tang D, Liao G, Fang W, Zhang X (2017) Prevalence of prostatitis-like symptoms and outcomes of NIH-CPSI in outpatients with lifelong and acquired PE: based on a large cross-sectional study in China. Biomed Res Int 2017:3473796. https:\/\/doi.org\/10.1155\/2017\/3473796","journal-title":"Biomed Res Int"},{"issue":"1","key":"3183_CR41","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.gene.2015.06.018","volume":"570","author":"AD Zuehlke","year":"2015","unstructured":"Zuehlke AD, Beebe K, Neckers L, Prince T (2015) Regulation and function of the human HSP90AA1 gene. Gene 570(1):8\u201316. https:\/\/doi.org\/10.1016\/j.gene.2015.06.018","journal-title":"Gene"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-024-03183-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00210-024-03183-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-024-03183-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T08:40:24Z","timestamp":1730191224000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00210-024-03183-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,1]]},"references-count":41,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["3183"],"URL":"https:\/\/doi.org\/10.1007\/s00210-024-03183-8","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,1]]},"assertion":[{"value":"23 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 June 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}