{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T10:01:42Z","timestamp":1767866502330,"version":"3.49.0"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T00:00:00Z","timestamp":1737072000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T00:00:00Z","timestamp":1737072000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch Pharmacol"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1007\/s00210-024-03728-x","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T06:00:21Z","timestamp":1737093621000},"page":"8511-8523","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Weekly administration of betulinic acid prevents development of chronic renal failure from acute renal failure in folic acid-induced mouse model of kidney injury"],"prefix":"10.1007","volume":"398","author":[{"given":"Bency Elsa","family":"Johnson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. V.","family":"Haritha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karikalan","family":"Mathesh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beena","family":"Vamadevan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anshuk","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. A.","family":"Aneesha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil E.","family":"Jadhav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subhashree","family":"Parida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thakur Uttam","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhu Cholenahalli","family":"Lingaraju","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,1,17]]},"reference":[{"issue":"1","key":"3728_CR1","doi-asserted-by":"publisher","first-page":"8513","DOI":"10.1038\/s41598-023-35453-5","volume":"13","author":"OE Adeniyi","year":"2023","unstructured":"Adeniyi OE, Adebayo OA, Akinloye O, Adaramoye OA (2023) Combined cerium and zinc oxide nanoparticles induced hepato-renal damage in rats through oxidative stress mediated inflammation. Sci Rep 13(1):8513. https:\/\/doi.org\/10.1038\/s41598-023-35453-5","journal-title":"Sci Rep"},{"key":"3728_CR2","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.freeradbiomed.2020.04.016","volume":"154","author":"OE Aparicio-Trejo","year":"2020","unstructured":"Aparicio-Trejo OE, Avila-Rojas SH, Tapia E, Rojas-Morales P, Le\u00f3n-Contreras JC, Mart\u00ednez-Klimova E, Hern\u00e1ndez-Pando R, S\u00e1nchez-Lozada LG, Pedraza-Chaverri J (2020) Chronic impairment of mitochondrial bioenergetics and beta-oxidation promotes experimental AKI-to-CKD transition induced by folic acid. Free Radic Biol Med 154:18\u201332. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2020.04.016","journal-title":"Free Radic Biol Med"},{"key":"3728_CR3","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1006\/abio.1976.9999","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248\u2013254. https:\/\/doi.org\/10.1006\/abio.1976.9999","journal-title":"Anal Biochem"},{"issue":"1","key":"3728_CR4","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1515\/biol-2022-0482","volume":"17","author":"Z Cheng","year":"2022","unstructured":"Cheng Z, Zhang X, Zhang Y, Li L, Chen P (2022) Role of MMP-2 and CD147 in kidney fibrosis. Open Life Sci 17(1):1182\u20131190. https:\/\/doi.org\/10.1515\/biol-2022-0482","journal-title":"Open Life Sci"},{"issue":"1","key":"3728_CR5","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s40635-017-0130-9","volume":"5","author":"L Constantino","year":"2017","unstructured":"Constantino L, Galant LS, Vuolo F, Guarido KL, Kist LW, de Oliveira GMT, Pasquali MAB, de Souza CT, da Silva-Santos JE, Bogo MR, Moreira JCF, Ritter C, Dal-Pizzol F (2017) Extracellular superoxide dismutase is necessary to maintain renal blood flow during sepsis development. Intensive Care Med Exp 5(1):15. https:\/\/doi.org\/10.1186\/s40635-017-0130-9","journal-title":"Intensive Care Med Exp"},{"issue":"1","key":"3728_CR6","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.cmet.2016.08.009","volume":"25","author":"GS Ducker","year":"2017","unstructured":"Ducker GS, Rabinowitz JD (2017) One-carbon metabolism in health and disease. Cell Metab 25(1):27\u201342. https:\/\/doi.org\/10.1016\/j.cmet.2016.08.009","journal-title":"Cell Metab"},{"key":"3728_CR7","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.toxlet.2018.09.003","volume":"299","author":"R Fan","year":"2018","unstructured":"Fan R, Hu PC, Wang Y, Lin HY, Su K, Feng XS, Wei L, Yang F (2018) Betulinic acid protects mice from cadmium chloride-induced toxicity by inhibiting cadmium-induced apoptosis in kidney and liver. Toxicol Lett 299:56\u201366. https:\/\/doi.org\/10.1016\/j.toxlet.2018.09.003","journal-title":"Toxicol Lett"},{"issue":"10159","key":"3728_CR8","doi-asserted-by":"publisher","first-page":"2052","DOI":"10.1016\/S0140-6736(18)31694-5","volume":"392","author":"KJ Foreman","year":"2018","unstructured":"Foreman KJ, Marquez N, Dolgert A, Fukutaki K, Fullman N, McGaughey M et al (2018) Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016\u201340 for 195 countries and territories. Lancet 392(10159):2052\u20132090. https:\/\/doi.org\/10.1016\/S0140-6736(18)31694-5","journal-title":"Lancet"},{"issue":"4","key":"3728_CR9","doi-asserted-by":"publisher","first-page":"F1098","DOI":"10.1152\/ajprenal.00199.2018","volume":"315","author":"Y Fu","year":"2018","unstructured":"Fu Y, Tang C, Cai J, Chen G, Zhang D, Dong Z (2018) Rodent models of AKI-CKD transition. Am J Physiol Renal Physiol 315(4):F1098\u2013F1106. https:\/\/doi.org\/10.1152\/ajprenal.00199.2018","journal-title":"Am J Physiol Renal Physiol"},{"key":"3728_CR10","doi-asserted-by":"publisher","first-page":"101905","DOI":"10.1016\/j.tice.2022.101905","volume":"79","author":"CV Haritha","year":"2022","unstructured":"Haritha CV, Lingaraju MC, Mathesh K, Jadhav SE, Shyamkumar TS, Aneesha VA, Parida S, Singh TU, Kumar D (2022) PRE-084 ameliorates adenine-induced renal fibrosis in rats. Tissue Cell 79:101905. https:\/\/doi.org\/10.1016\/j.tice.2022.101905","journal-title":"Tissue Cell"},{"issue":"11","key":"3728_CR11","doi-asserted-by":"publisher","first-page":"3000","DOI":"10.3390\/cells10113000","volume":"10","author":"M Iwaszko","year":"2021","unstructured":"Iwaszko M, Bia\u0142y S, Bogunia-Kubik K (2021) Significance of Interleukin (IL)-4 and IL-13 in Inflammatory Arthritis. Cells 10(11):3000. https:\/\/doi.org\/10.3390\/cells10113000","journal-title":"Cells"},{"key":"3728_CR12","doi-asserted-by":"publisher","first-page":"735014","DOI":"10.3389\/fimmu.2021.735014","volume":"12","author":"B Jiao","year":"2021","unstructured":"Jiao B, An C, Tran M, Du H, Wang P, Zhou D, Wang Y (2021) Pharmacological inhibition of STAT6 ameliorates myeloid fibroblast activation and alternative macrophage polarization in renal fibrosis. Front Immunol 12:735014. https:\/\/doi.org\/10.3389\/fimmu.2021.735014","journal-title":"Front Immunol"},{"issue":"3","key":"3728_CR13","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/s00210-017-1455-3","volume":"391","author":"J Kalra","year":"2018","unstructured":"Kalra J, Lingaraju MC, Mathesh K, Kumar D, Parida S, Singh TU, Sharma AK, Kumar D, Tandan SK (2018) Betulinic acid alleviates dextran sulfate sodium-induced colitis and visceral pain in mice. Naunyn Schmiedebergs Arch Pharmacol 391(3):285\u2013297. https:\/\/doi.org\/10.1007\/s00210-017-1455-3","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"4","key":"3728_CR14","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s40139-013-0026-7","volume":"1","author":"R Kramann","year":"2013","unstructured":"Kramann R, DiRocco DP, Maarouf OH, Humphreys BD (2013) Matrix-producing cells in chronic kidney disease: origin, regulation, and activation. Curr Pathobiol Rep 1(4):301\u2013311. https:\/\/doi.org\/10.1007\/s40139-013-0026-7","journal-title":"Curr Pathobiol Rep"},{"key":"3728_CR15","doi-asserted-by":"publisher","first-page":"105294","DOI":"10.1016\/j.ebiom.2024.105294","volume":"107","author":"ZL Li","year":"2024","unstructured":"Li ZL, Li XY, Zhou Y, Wang B, Lv LL, Liu BC (2024) Renal tubular epithelial cells response to injury in acute kidney injury. EBioMedicine 107:105294. https:\/\/doi.org\/10.1016\/j.ebiom.2024.105294","journal-title":"EBioMedicine"},{"issue":"2","key":"3728_CR16","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1016\/j.jss.2014.09.008","volume":"193","author":"MC Lingaraju","year":"2015","unstructured":"Lingaraju MC, Pathak NN, Begum J, Balaganur V, Bhat RA, Ram M, Kumar D, Kumar D, Tandan SK (2015) Betulinic acid negates oxidative lung injury in surgical sepsis model. J Surg Res 193(2):856\u2013867. https:\/\/doi.org\/10.1016\/j.jss.2014.09.008","journal-title":"J Surg Res"},{"issue":"1","key":"3728_CR17","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.cyto.2014.09.004","volume":"71","author":"MC Lingaraju","year":"2015","unstructured":"Lingaraju MC, Pathak NN, Begum J, Balaganur V, Bhat RA, Ramachandra HD, Ayanur A, Ram M, Singh V, Kumar D, Kumar D (2015) Betulinic acid attenuates lung injury by modulation of inflammatory cytokine response in experimentally-induced polymicrobial sepsis in mice. Cytokine 71(1):101\u2013108. https:\/\/doi.org\/10.1016\/j.cyto.2014.09.004","journal-title":"Cytokine"},{"key":"3728_CR18","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.ejps.2015.01.001","volume":"70","author":"MC Lingaraju","year":"2015","unstructured":"Lingaraju MC, Pathak NN, Begum J, Balaganur V, Ramachandra HD, Bhat RA, Ram M, Singh V, Kandasamy K, Kumar D, Kumar D (2015) Betulinic acid attenuates renal oxidative stress and inflammation in experimental model of murine polymicrobial sepsis. Eur J Pharm Sci 70:12\u201321. https:\/\/doi.org\/10.1016\/j.ejps.2015.01.001","journal-title":"Eur J Pharm Sci"},{"issue":"7","key":"3728_CR19","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1097\/CM9.0000000000002100","volume":"135","author":"X Meng","year":"2022","unstructured":"Meng X, Jin J, Lan HY (2022) Driving role of macrophages in transition from acute kidney injury to chronic kidney disease. Chin Med J (Engl) 135(7):757\u2013766. https:\/\/doi.org\/10.1097\/CM9.0000000000002100","journal-title":"Chin Med J (Engl)"},{"key":"3728_CR20","doi-asserted-by":"publisher","first-page":"101851","DOI":"10.1016\/j.redox.2020.101851","volume":"40","author":"V Miguel","year":"2021","unstructured":"Miguel V, Ramos R, Garc\u00eda-Bermejo L, Rodr\u00edguez-Puyol D, Lamas S (2021) The program of renal fibrogenesis is controlled by microRNAs regulating oxidative metabolism. Redox Biol 40:101851. https:\/\/doi.org\/10.1016\/j.redox.2020.101851","journal-title":"Redox Biol"},{"issue":"18","key":"3728_CR21","doi-asserted-by":"publisher","first-page":"14019","DOI":"10.3390\/ijms241814019","volume":"24","author":"A Niculae","year":"2023","unstructured":"Niculae A, Gherghina ME, Peride I, Tiglis M, Nechita AM, Checherita IA (2023) Pathway from acute kidney injury to chronic kidney disease: molecules involved in renal fibrosis. Int J Mol Sci 24(18):14019. https:\/\/doi.org\/10.3390\/ijms241814019","journal-title":"Int J Mol Sci"},{"key":"3728_CR22","doi-asserted-by":"publisher","unstructured":"Novakovic ZS, Durdov MG, Puljak L, Saraga M, Ljutic D, Filipovic T, Pastar Z, Bendic A, Vukojevic K (2012) The interstitial expression of alpha-smooth muscle actin in glomerulonephritis is associated with renal function. Med Sci Monit 18(4):CR235- CR240. https:\/\/doi.org\/10.12659\/msm.882623","DOI":"10.12659\/msm.882623"},{"issue":"1","key":"3728_CR23","doi-asserted-by":"publisher","first-page":"408","DOI":"10.3390\/ijms22010408","volume":"22","author":"S Panizo","year":"2021","unstructured":"Panizo S, Mart\u00ednez-Arias L, Alonso-Montes C, Cannata P, Mart\u00edn-Carro B, Fern\u00e1ndez-Mart\u00edn JL, Naves-D\u00edaz M, Carrillo-L\u00f3pez N, Cannata-And\u00eda JB (2021) Fibrosis in chronic kidney disease: pathogenesis and consequences. Int J Mol Sci 22(1):408. https:\/\/doi.org\/10.3390\/ijms22010408","journal-title":"Int J Mol Sci"},{"issue":"12","key":"3728_CR24","doi-asserted-by":"publisher","first-page":"2860","DOI":"10.3390\/cancers13122860","volume":"13","author":"AR Poh","year":"2021","unstructured":"Poh AR, Ernst M (2021) Tumor-associated macrophages in pancreatic ductal adenocarcinoma: therapeutic opportunities and clinical challenges. Cancers (Basel) 13(12):2860. https:\/\/doi.org\/10.3390\/cancers13122860","journal-title":"Cancers (Basel)"},{"issue":"4","key":"3728_CR25","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/j.ekir.2017.02.021","volume":"2","author":"HA Polinder-Bos","year":"2017","unstructured":"Polinder-Bos HA, Nacak H, Dekker FW, Bakker SJL, Gaillard CAJM, Gansevoort RT (2017) Low urinary creatinine excretion is associated with self-reported frailty in patients with advanced chronic kidney disease. Kidney Int Rep 2(4):676\u2013685. https:\/\/doi.org\/10.1016\/j.ekir.2017.02.021","journal-title":"Kidney Int Rep"},{"issue":"6","key":"3728_CR26","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1681\/ASN.0000000000000140","volume":"34","author":"R Rana","year":"2023","unstructured":"Rana R, Breyer MD (2023) Tackling AKI. J Am Soc Nephrol 34(6):935\u2013936. https:\/\/doi.org\/10.1681\/ASN.0000000000000140","journal-title":"J Am Soc Nephrol"},{"key":"3728_CR27","doi-asserted-by":"publisher","unstructured":"Rattanasinganchan P, Sopitthummakhun K, Doi K, Hu X, Payne M, Pisitkun T, Leelahavanichkul A (2016) A folic acid\u2010induced rat model of renal injury to identify biomarkers of tubulointerstitial fibrosis from urinary exosomes. Asian Biomed 10(5):491\u2010502. https:\/\/doi.org\/10.5372\/1905-7415.1005.513","DOI":"10.5372\/1905-7415.1005.513"},{"issue":"4","key":"3728_CR28","first-page":"633","volume":"9","author":"H R\u00e9glier-Poupet","year":"1998","unstructured":"R\u00e9glier-Poupet H, Hakim J, Gougerot-Pocidalo MA, Elbim C (1998) Absence of regulation of human polymorphonuclear oxidative burst by interleukin-10, interleukin-4, interleukin-13 and transforming growth factor-beta in whole blood. Eur Cytokine Netw 9(4):633\u2013638","journal-title":"Eur Cytokine Netw"},{"issue":"12","key":"3728_CR29","doi-asserted-by":"publisher","first-page":"2215","DOI":"10.3390\/jcm8122215","volume":"8","author":"S Rubin","year":"2019","unstructured":"Rubin S, Orieux A, Clouzeau B, Rigothier C, Combe C, Gruson D, Boyer A (2019) The incidence of chronic kidney disease three years after non-severe acute kidney injury in critically ill patients: a single-center cohort study. J Clin Med 8(12):2215. https:\/\/doi.org\/10.3390\/jcm8122215","journal-title":"J Clin Med"},{"issue":"10","key":"3728_CR30","doi-asserted-by":"publisher","first-page":"2353","DOI":"10.3390\/nu11102353","volume":"11","author":"SL Samodelov","year":"2019","unstructured":"Samodelov SL, Gai Z, Kullak-Ublick GA, Visentin M (2019) Renal reabsorption of folates: pharmacological and toxicological snapshots. Nutrients 11(10):2353. https:\/\/doi.org\/10.3390\/nu11102353","journal-title":"Nutrients"},{"key":"3728_CR31","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1016\/j.biopha.2017.01.181","volume":"89","author":"A Sharma","year":"2017","unstructured":"Sharma A, Thakur R, Lingaraju MC, Kumar D, Mathesh K, Telang AG, Singh TU, Kumar D (2017) Betulinic acid attenuates renal fibrosis in rat chronic kidney disease model. Biomed Pharmacother 89:796\u2013804. https:\/\/doi.org\/10.1016\/j.biopha.2017.01.181","journal-title":"Biomed Pharmacother"},{"issue":"8","key":"3728_CR32","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrp.2021.100515","volume":"2","author":"B Sun","year":"2021","unstructured":"Sun B (2021) The mechanics of fibrillar collagen extracellular matrix. Cell Rep Phys Sci 2(8):100515. https:\/\/doi.org\/10.1016\/j.xcrp.2021.100515","journal-title":"Cell Rep Phys Sci"},{"key":"3728_CR33","doi-asserted-by":"publisher","unstructured":"Verma S, Singh P, Khurana S, Ganguly NK, Kukreti R, Saso L, Rana DS, Taneja V, Bhargava V (2021) Implications of oxidative stress in chronic kidney disease: a review on current concepts and therapies. Kidney Res Clin Pract 40(2):183-193. https:\/\/doi.org\/10.23876\/j.krcp.20.163","DOI":"10.23876\/j.krcp.20.163"},{"issue":"11\u201312","key":"3728_CR34","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1080\/10715762.2021.2024529","volume":"55","author":"Y Wang","year":"2021","unstructured":"Wang Y, Wu CJ, Du Y, Liu YQ, Cai JR, Wu XQ, Hu SQ (2021) SIRT2 tyrosine nitration by peroxynitrite in response to renal ischemia\/reperfusion injury. Free Radic Res 55(11\u201312):1104\u20131118. https:\/\/doi.org\/10.1080\/10715762.2021.2024529","journal-title":"Free Radic Res"},{"key":"3728_CR35","doi-asserted-by":"publisher","unstructured":"Wills ED (1969) Lipid peroxide formation in microsomes. Relationship of hydroxylation to lipid peroxide formation. Biochem J 113(2):333-341. https:\/\/doi.org\/10.1042\/bj1130333","DOI":"10.1042\/bj1130333"},{"issue":"10","key":"3728_CR36","doi-asserted-by":"publisher","first-page":"1825","DOI":"10.1681\/ASN.2019010068","volume":"30","author":"L Xu","year":"2019","unstructured":"Xu L, Sharkey D, Cantley LG (2019) Tubular GM-CSF Promotes late MCP-1\/CCR2-mediated fibrosis and inflammation after ischemia\/reperfusion injury. J Am Soc Nephrol 30(10):1825\u20131840. https:\/\/doi.org\/10.1681\/ASN.2019010068","journal-title":"J Am Soc Nephrol"},{"issue":"4","key":"3728_CR37","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1002\/ame2.12194","volume":"4","author":"LJ Yan","year":"2021","unstructured":"Yan LJ (2021) Folic acid induced animal model of kidney disease. Anim Models Exp Med 4(4):329\u2013342. https:\/\/doi.org\/10.1002\/ame2.12194","journal-title":"Anim Models Exp Med"},{"issue":"5","key":"3728_CR38","doi-asserted-by":"publisher","first-page":"730","DOI":"10.3390\/biom11050730","volume":"11","author":"LJ Yan","year":"2021","unstructured":"Yan LJ (2021) NADH\/NAD+ redox imbalance and diabetic kidney disease. Biomolecules 11(5):730. https:\/\/doi.org\/10.3390\/biom11050730","journal-title":"Biomolecules"},{"issue":"2","key":"3728_CR39","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.kint.2016.08.020","volume":"91","author":"MZ Zhang","year":"2017","unstructured":"Zhang MZ, Wang X, Wang Y, Niu A, Wang S, Zou C, Harris RC (2017) IL-4\/ IL-13\u2013mediated polarization of renal macrophages\/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury. Kidney Int 91(2):375\u2013386. https:\/\/doi.org\/10.1016\/j.kint.2016.08.020","journal-title":"Kidney Int"},{"issue":"1","key":"3728_CR40","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1038\/s41392-021-00658-5","volume":"6","author":"H Zhao","year":"2021","unstructured":"Zhao H, Wu L, Yan G, Chen Y, Zhou M, Wu Y, Li Y (2021) Inflammation and tumor progression: signaling pathways and targeted intervention. Signal Transduct Target Ther 6(1):263. https:\/\/doi.org\/10.1038\/s41392-021-00658-5","journal-title":"Signal Transduct Target Ther"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-024-03728-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00210-024-03728-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-024-03728-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T04:50:59Z","timestamp":1752555059000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00210-024-03728-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,17]]},"references-count":40,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["3728"],"URL":"https:\/\/doi.org\/10.1007\/s00210-024-03728-x","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,17]]},"assertion":[{"value":"15 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Animal eexperimental protocols were approved by the Institutional Animal Ethics Committee of ICAR-Indian Veterinary Research Institute, Izatnagar.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical statement"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}