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According to the literature, ICS was induced by constructing a MCAO model. In brief, Sprague\u2013Dawley (SD) rats (6\u20138 weeks, 250\u2013280 g,\n                      n\n                      \u2009= 6) were purchased from Shanghai SLAC Laboratory Animal Co., Ltd. (Shanghai, China).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}