{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T03:03:12Z","timestamp":1784775792906,"version":"3.55.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T00:00:00Z","timestamp":1778198400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T00:00:00Z","timestamp":1778198400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch Pharmacol"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1007\/s00210-026-05400-y","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T05:35:53Z","timestamp":1778218553000},"page":"16153-16172","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pan-cancer multi-omics analysis identifies TOMM22 as an oncogenic driver and therapeutic target in LIHC via ferroptosis regulation"],"prefix":"10.1007","volume":"399","author":[{"given":"Wei","family":"Cheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengdan","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,8]]},"reference":[{"issue":"3","key":"5400_CR1","first-page":"229","volume":"74","author":"F Bray","year":"2024","unstructured":"Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74(3):229\u2013263","journal-title":"CA Cancer J Clin"},{"issue":"20","key":"5400_CR2","doi-asserted-by":"publisher","first-page":"3045","DOI":"10.1016\/j.febslet.2008.07.047","volume":"582","author":"PF Cartron","year":"2008","unstructured":"Cartron PF, Bellot G, Oliver L, Grandier-Vazeille X, Manon S, Vallette FM (2008) Bax inserts into the mitochondrial outer membrane by different mechanisms. FEBS Lett 582(20):3045\u20133051","journal-title":"FEBS Lett"},{"key":"5400_CR3","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-026-03048-4","author":"S Castelli","year":"2026","unstructured":"Castelli S, De Cristofaro A, Desideri E, Salvi E, Ciccarone F, Ciriolo MR (2026) ATGL sensitizes hepatocellular carcinoma cells to genotoxic drugs by modulating p53 acetylation\/phosphorylation status. Cell Death Discov. https:\/\/doi.org\/10.1038\/s41420-026-03048-4","journal-title":"Cell Death Discov"},{"issue":"7","key":"5400_CR4","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1002\/cac2.70008","volume":"45","author":"X Cen","year":"2025","unstructured":"Cen X, Lan Y, Zou J, Chen R, Hu C, Tong Y, Zhang C, Chen J, Wang Y, Zhou R et al (2025) Pan-cancer analysis shapes the understanding of cancer biology and medicine. Cancer Commun 45(7):728\u2013746","journal-title":"Cancer Commun"},{"issue":"1","key":"5400_CR5","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1186\/s12943-024-02101-z","volume":"23","author":"YT Chan","year":"2024","unstructured":"Chan YT, Zhang C, Wu J, Lu P, Xu L, Yuan H, Feng Y, Chen ZS, Wang N (2024) Biomarkers for diagnosis and therapeutic options in hepatocellular carcinoma. Mol Cancer 23(1):189","journal-title":"Mol Cancer"},{"key":"5400_CR6","doi-asserted-by":"publisher","DOI":"10.1007\/s12033-025-01404-w","author":"W Cheng","year":"2025","unstructured":"Cheng W, Lin P (2025) DSCC1 identified as promising tumor biomarker and potential therapeutic target through comprehensive multi-omics analysis and experimental validation. Mol Biotechnol. https:\/\/doi.org\/10.1007\/s12033-025-01404-w","journal-title":"Mol Biotechnol"},{"issue":"W1","key":"5400_CR7","doi-asserted-by":"publisher","first-page":"W534","DOI":"10.1093\/nar\/gkaf388","volume":"53","author":"H Cui","year":"2025","unstructured":"Cui H, Zhao G, Lu Y, Zuo S, Duan D, Luo X, Zhao H, Li J, Zeng Z, Chen Q et al (2025) TIMER3: an enhanced resource for tumor immune analysis. Nucleic Acids Res 53(W1):W534-w541","journal-title":"Nucleic Acids Res"},{"issue":"D1","key":"5400_CR8","doi-asserted-by":"publisher","first-page":"D1407","DOI":"10.1093\/nar\/gkad753","volume":"52","author":"Y Deng","year":"2024","unstructured":"Deng Y, Chen P, Xiao J, Li M, Shen J, Qin S, Jia T, Li C, Chang A, Zhang W et al (2024) SCAR: single-cell and spatially-resolved cancer resources. Nucleic Acids Res 52(D1):D1407\u2013D1417","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"5400_CR9","doi-asserted-by":"publisher","first-page":"48","DOI":"10.2174\/0113892029308243240709073945","volume":"26","author":"IP Gudivada","year":"2025","unstructured":"Gudivada IP, Amajala KC (2025) Integrative bioinformatics analysis for targeting hub genes in hepatocellular carcinoma treatment. Curr Genomics 26(1):48\u201380","journal-title":"Curr Genomics"},{"issue":"6","key":"5400_CR10","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2024.101312","volume":"11","author":"H Guo","year":"2024","unstructured":"Guo H, Su R, Lu X, Zhang H, Wei X, Xu X (2024) ZIP4 inhibits Ephrin-B1 ubiquitination, activating Wnt5A\/JNK\/ZEB1 to promote liver cancer metastasis. Genes Dis 11(6)","journal-title":"Genes Dis"},{"issue":"2","key":"5400_CR11","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1158\/1541-7786.MCR-23-0138","volume":"22","author":"MO Haastrup","year":"2024","unstructured":"Haastrup MO, Vikramdeo KS, Anand S, Khan MA, Carter JE, Singh S, Singh AP, Dasgupta S (2024) Mitochondrial translocase TOMM22 is overexpressed in pancreatic cancer and promotes aggressive growth by modulating mitochondrial protein import and function. Mol Cancer Res 22(2):197\u2013208","journal-title":"Mol Cancer Res"},{"issue":"42","key":"5400_CR12","doi-asserted-by":"publisher","first-page":"41462","DOI":"10.1074\/jbc.M307047200","volume":"278","author":"C Horie","year":"2003","unstructured":"Horie C, Suzuki H, Sakaguchi M, Mihara K (2003) Targeting and assembly of mitochondrial tail-anchored protein Tom5 to the TOM complex depend on a signal distinct from that of tail-anchored proteins dispersed in the membrane. J Biol Chem 278(42):41462\u201341471","journal-title":"J Biol Chem"},{"issue":"1","key":"5400_CR13","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-025-02869-z","volume":"12","author":"K Hu","year":"2025","unstructured":"Hu K, Li J, Chen K, Mi X, Pan Y, Tang J, Cao J, Zhong X (2025) Hypoxia-induced USP13 expression drives ferroptosis resistance and tumor immune evasion in hepatocellular carcinoma through the stabilization of ACLY. Cell Death Discov 12(1)","journal-title":"Cell Death Discov"},{"issue":"1","key":"5400_CR14","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2024.101395","volume":"12","author":"X Jiang","year":"2025","unstructured":"Jiang X, Xing L, Lu Y, Qin R, Wang L, Song S, Liu X, Xie S, Li S, Lu D (2025) CARM1 accelerates the growth of liver cancer cells by enhancing ARAF. Genes Dis 12(1)","journal-title":"Genes Dis"},{"issue":"2","key":"5400_CR15","doi-asserted-by":"publisher","first-page":"782","DOI":"10.21037\/tcr-23-785","volume":"13","author":"Q Ke","year":"2024","unstructured":"Ke Q, Wang Y, Deng Y, Wang J, Yuan M, Liang A, Wang J, Gong Q (2024) Identification and validation of mitophagy-related signatures as a novel prognostic model for colorectal cancer. Transl Cancer Res 13(2):782\u2013797","journal-title":"Transl Cancer Res"},{"issue":"11","key":"5400_CR16","doi-asserted-by":"publisher","first-page":"3236","DOI":"10.1038\/s41591-024-03215-z","volume":"30","author":"J Klughammer","year":"2024","unstructured":"Klughammer J, Abravanel DL, Segerstolpe \u00c5, Blosser TR, Goltsev Y, Cui Y, Goodwin DR, Sinha A, Ashenberg O, Slyper M et al (2024) A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features. Nat Med 30(11):3236\u20133249","journal-title":"Nat Med"},{"issue":"21","key":"5400_CR17","doi-asserted-by":"publisher","first-page":"e108","DOI":"10.1158\/0008-5472.CAN-17-0307","volume":"77","author":"T Li","year":"2017","unstructured":"Li T, Fan J, Wang B, Traugh N, Chen Q, Liu JS, Li B, Liu XS (2017) TIMER: a web server for comprehensive analysis of tumor-infiltrating immune cells. Cancer Res 77(21):e108\u2013e110","journal-title":"Cancer Res"},{"issue":"W1","key":"5400_CR18","doi-asserted-by":"publisher","first-page":"W509","DOI":"10.1093\/nar\/gkaa407","volume":"48","author":"T Li","year":"2020","unstructured":"Li T, Fu J, Zeng Z, Cohen D, Li J, Chen Q, Li B, Liu XS (2020) TIMER2.0 for analysis of tumor-infiltrating immune cells. Nucleic Acids Res 48(W1):W509-w514","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"5400_CR19","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1038\/s41388-022-02537-x","volume":"42","author":"D Li","year":"2023","unstructured":"Li D, Wang Y, Dong C, Chen T, Dong A, Ren J, Li W, Shu G, Yang J, Shen W et al (2023) CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1. Oncogene 42(2):83\u201398","journal-title":"Oncogene"},{"key":"5400_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2024.103087","volume":"71","author":"H Li","year":"2024","unstructured":"Li H, Yu K, Hu H, Zhang X, Zeng S, Li J, Dong X, Deng X, Zhang J, Zhang Y (2024) METTL17 coordinates ferroptosis and tumorigenesis by regulating mitochondrial translation in colorectal cancer. Redox Biol 71","journal-title":"Redox Biol"},{"key":"5400_CR21","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26178537","author":"L Li","year":"2025","unstructured":"Li L, Pan D, Ai R, Zhou Y (2025) Mitochondria-associated pathways in cancer and precancerous conditions: mechanistic insights. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms26178537","journal-title":"Int J Mol Sci"},{"issue":"21","key":"5400_CR22","doi-asserted-by":"publisher","first-page":"3771","DOI":"10.1093\/bioinformatics\/bty411","volume":"34","author":"CJ Liu","year":"2018","unstructured":"Liu CJ, Hu FF, Xia MX, Han L, Zhang Q, Guo AY (2018) GSCALite: a web server for gene set cancer analysis. Bioinformatics 34(21):3771\u20133772","journal-title":"Bioinformatics"},{"key":"5400_CR23","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbac558","author":"CJ Liu","year":"2023","unstructured":"Liu CJ, Hu FF, Xie GY, Miao YR, Li XW, Zeng Y, Guo AY (2023) GSCA: an integrated platform for gene set cancer analysis at genomic, pharmacogenomic and immunogenomic levels. Brief Bioinform. https:\/\/doi.org\/10.1093\/bib\/bbac558","journal-title":"Brief Bioinform"},{"issue":"6","key":"5400_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2025.101675","volume":"12","author":"Y Lu","year":"2025","unstructured":"Lu Y, Lu D (2025) circ-miR-524 accelerates the growth of liver cancer cells by inducing DNA damage repair through K-RAS. Genes Dis 12(6)","journal-title":"Genes Dis"},{"issue":"5","key":"5400_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2025.101512","volume":"12","author":"W Luo","year":"2025","unstructured":"Luo W, Zhou J, Yan Y, Xu X (2025) Ribosome biogenesis: a central player in liver diseases. Genes Dis 12(5)","journal-title":"Genes Dis"},{"issue":"1","key":"5400_CR26","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-025-02917-8","volume":"12","author":"O Mocellin","year":"2025","unstructured":"Mocellin O, Treillard S, Robinson A, Olczyk A, Olivier T, Ng CP, Stok A, van Tienderen G, Verstegen MMA, Heijmans J et al (2025) Modeling hepatocellular carcinoma and its microenvironment on a chip. Cell Death Discov 12(1)","journal-title":"Cell Death Discov"},{"issue":"1","key":"5400_CR27","doi-asserted-by":"publisher","first-page":"2","DOI":"10.2174\/0113892029273682240111052317","volume":"25","author":"R Mu","year":"2024","unstructured":"Mu R, Chang M, Feng C, Cui Y, Li T, Liu C, Wang Y, Guo X (2024) Analysis of the expression of PRDX6 in patients with hepatocellular carcinoma and its effect on the phenotype of hepatocellular carcinoma cells. Curr Genomics 25(1):2\u201311","journal-title":"Curr Genomics"},{"issue":"1","key":"5400_CR28","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-23280-z","volume":"12","author":"A Periasamy","year":"2022","unstructured":"Periasamy A, Mitchell N, Zaytseva O, Chahal AS, Zhao J, Colman PM, Quinn LM, Gulbis JM (2022) An increase in mitochondrial TOM activates apoptosis to drive retinal neurodegeneration. Sci Rep 12(1)","journal-title":"Sci Rep"},{"issue":"11","key":"5400_CR29","doi-asserted-by":"publisher","first-page":"R412","DOI":"10.1016\/S0960-9822(00)00507-8","volume":"10","author":"N Pfanner","year":"2000","unstructured":"Pfanner N (2000) Protein sorting: recognizing mitochondrial presequences. Curr Biol 10(11):R412\u2013R415","journal-title":"Curr Biol"},{"key":"5400_CR30","doi-asserted-by":"publisher","DOI":"10.3390\/cells10051164","author":"AS Pitt","year":"2021","unstructured":"Pitt AS, Buchanan SK (2021) A biochemical and structural understanding of TOM complex interactions and implications for human health and disease. Cells. https:\/\/doi.org\/10.3390\/cells10051164","journal-title":"Cells"},{"issue":"1","key":"5400_CR31","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-026-02940-3","volume":"12","author":"S Sabbioni","year":"2026","unstructured":"Sabbioni S, Guerriero P, Shankaraiah RC, Masatti L, Michilli A, Bassi C, D\u2019Abundo L, Moshiri F, De Siena B, Simoni E et al (2026) Targeting metabolic vulnerabilities: REV-ERB agonist SR9009 potentiates sorafenib efficacy in liver cancer. Cell Death Discov 12(1)","journal-title":"Cell Death Discov"},{"issue":"8036","key":"5400_CR32","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1038\/s41586-024-08053-0","volume":"634","author":"ID Sadien","year":"2024","unstructured":"Sadien ID, Adler S, Mehmed S, Bailey S, Sawle A, Couturier D-L, Eldridge M, Adams DJ, Kemp R, Louren\u00e7o FC et al (2024) Polyclonality overcomes fitness barriers in Apc-driven tumorigenesis. Nature 634(8036):1196\u20131203","journal-title":"Nature"},{"key":"5400_CR33","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17183062","author":"S Sathe","year":"2025","unstructured":"Sathe S, Li Q, Jung J, Wu J (2025) Targeting the mitochondria in high-grade gliomas. Cancers Basel. https:\/\/doi.org\/10.3390\/cancers17183062","journal-title":"Cancers Basel"},{"issue":"16","key":"5400_CR34","doi-asserted-by":"publisher","first-page":"4389","DOI":"10.1016\/j.cell.2024.05.039","volume":"187","author":"SR Savage","year":"2024","unstructured":"Savage SR, Yi X, Lei JT, Wen B, Zhao H, Liao Y, Jaehnig EJ, Somes LK, Shafer PW, Lee TD et al (2024) Pan-cancer proteogenomics expands the landscape of therapeutic targets. Cell 187(16):4389-4407.e4315","journal-title":"Cell"},{"key":"5400_CR35","doi-asserted-by":"publisher","DOI":"10.2174\/0118761429310703240823045808","volume":"17","author":"B Sensi","year":"2024","unstructured":"Sensi B, Angelico R, Toti L, Conte L, Coppola A, Tisone G, Manzia TM (2024) Mechanism, potential, and concerns of immunotherapy for hepatocellular carcinoma and liver transplantation. Curr Mol Pharmacol 17","journal-title":"Curr Mol Pharmacol"},{"issue":"1","key":"5400_CR36","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/s13045-025-01684-4","volume":"18","author":"T Shang","year":"2025","unstructured":"Shang T, Jia Z, Li J, Cao H, Xu H, Cong L, Ma D, Wang X, Liu J (2025) Unraveling the triad of hypoxia, cancer cell stemness, and drug resistance. J Hematol Oncol 18(1):32","journal-title":"J Hematol Oncol"},{"issue":"7","key":"5400_CR37","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1007\/s00204-013-1034-4","volume":"87","author":"K Sinha","year":"2013","unstructured":"Sinha K, Das J, Pal PB, Sil PC (2013) Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis. Arch Toxicol 87(7):1157\u20131180","journal-title":"Arch Toxicol"},{"issue":"7","key":"5400_CR38","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1038\/s41556-018-0124-1","volume":"20","author":"JB Spinelli","year":"2018","unstructured":"Spinelli JB, Haigis MC (2018) The multifaceted contributions of mitochondria to cellular metabolism. Nat Cell Biol 20(7):745\u2013754","journal-title":"Nat Cell Biol"},{"issue":"7","key":"5400_CR39","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1016\/j.cell.2024.02.009","volume":"187","author":"C Swanton","year":"2024","unstructured":"Swanton C, Bernard E, Abbosh C, Andr\u00e9 F, Auwerx J, Balmain A, Bar-Sagi D, Bernards R, Bullman S, DeGregori J et al (2024) Embracing cancer complexity: hallmarks of systemic disease. Cell 187(7):1589\u20131616","journal-title":"Cell"},{"key":"5400_CR40","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.202002179","author":"JX Tan","year":"2020","unstructured":"Tan JX, Finkel T (2020) Mitochondria as intracellular signaling platforms in health and disease. J Cell Biol. https:\/\/doi.org\/10.1083\/jcb.202002179","journal-title":"J Cell Biol"},{"key":"5400_CR41","doi-asserted-by":"publisher","DOI":"10.3390\/cimb47090760","author":"S Tang","year":"2025","unstructured":"Tang S, Yang B (2025) The diverse roles of mitochondria in regulating cancer metastasis. Curr Issues Mol Biol. https:\/\/doi.org\/10.3390\/cimb47090760","journal-title":"Curr Issues Mol Biol"},{"key":"5400_CR42","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1132559","volume":"13","author":"DY Tu","year":"2023","unstructured":"Tu DY, Cao J, Zhou J, Su BB, Wang SY, Jiang GQ, Jin SJ, Zhang C, Peng R, Bai DS (2023) Identification of the mitophagy-related diagnostic biomarkers in hepatocellular carcinoma based on machine learning algorithm and construction of prognostic model. Front Oncol 13","journal-title":"Front Oncol"},{"issue":"2","key":"5400_CR43","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/j.cellsig.2013.11.016","volume":"26","author":"GV Veresov","year":"2014","unstructured":"Veresov GV, Davidovskii AI (2014) Structural insights into proapoptotic signaling mediated by MTCH2, VDAC2, TOM40 and TOM22. Cell Signal 26(2):370\u2013382","journal-title":"Cell Signal"},{"issue":"3","key":"5400_CR44","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1007\/s10555-023-10084-4","volume":"42","author":"Y Wang","year":"2023","unstructured":"Wang Y, Deng B (2023) Hepatocellular carcinoma: molecular mechanism, targeted therapy, and biomarkers. Cancer Metastasis Rev 42(3):629\u2013652","journal-title":"Cancer Metastasis Rev"},{"issue":"D1","key":"5400_CR45","doi-asserted-by":"publisher","first-page":"D882","DOI":"10.1093\/nar\/gkad782","volume":"52","author":"G Wang","year":"2024","unstructured":"Wang G, Wu S, Xiong Z, Qu H, Fang X, Bao Y (2024) CROST: a comprehensive repository of spatial transcriptomics. Nucleic Acids Res 52(D1):D882-d890","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"5400_CR46","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1038\/s41420-025-02397-w","volume":"11","author":"J Xiao","year":"2025","unstructured":"Xiao J, Liu T, Zeng F, Zhang J (2025) New insights into T cell metabolism in liver cancer: from mechanism to therapy. Cell Death Discov 11(1):118","journal-title":"Cell Death Discov"},{"issue":"1","key":"5400_CR47","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2025.101715","volume":"13","author":"S Xie","year":"2026","unstructured":"Xie S, Jiang X, Liu X, Song S, Wang L, Li S, Lu D (2026) CALR accelerates the growth of liver cancer cells by enhancing telomere activity via ARAF. Genes Dis 13(1)","journal-title":"Genes Dis"},{"key":"5400_CR48","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.917584","volume":"13","author":"W Xu","year":"2022","unstructured":"Xu W, Zhao D, Huang X, Zhang M, Yin M, Liu L, Wu H, Weng Z, Xu C (2022) The prognostic value and clinical significance of mitophagy-related genes in hepatocellular carcinoma. Front Genet 13","journal-title":"Front Genet"},{"key":"5400_CR49","volume":"17","author":"W Xu","year":"2024","unstructured":"Xu W, Liao S, Hu Y, Huang Y, Zhou J (2024) Upregulation of miR-3130-5p enhances hepatocellular carcinoma growth by suppressing ferredoxin 1: miR-3130-5p enhances HCC growth via inhibiting FDX1. Curr Mol Pharmacol 17","journal-title":"Curr Mol Pharmacol"},{"issue":"1","key":"5400_CR50","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-23463-8","volume":"12","author":"C Zhang","year":"2022","unstructured":"Zhang C, Zeng C, Xiong S, Zhao Z, Wu G (2022) A mitophagy-related gene signature associated with prognosis and immune microenvironment in colorectal cancer. Sci Rep 12(1)","journal-title":"Sci Rep"},{"issue":"1","key":"5400_CR51","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-025-07078-x","volume":"23","author":"Z Zhao","year":"2025","unstructured":"Zhao Z, Ren Y, Yuan M, Liu G, Sun J (2025) The molecular mechanisms of mitochondrial dynamics and mitophagy and their complex association with cancer drug resistance. J Transl Med 23(1)","journal-title":"J Transl Med"},{"issue":"1","key":"5400_CR52","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1038\/s41392-024-01823-2","volume":"9","author":"Y Zhou","year":"2024","unstructured":"Zhou Y, Tao L, Qiu J, Xu J, Yang X, Zhang Y, Tian X, Guan X, Cen X, Zhao Y (2024) Tumor biomarkers for diagnosis, prognosis and targeted therapy. Signal Transduct Target Ther 9(1):132","journal-title":"Signal Transduct Target Ther"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-026-05400-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00210-026-05400-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-026-05400-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T03:00:07Z","timestamp":1784775607000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00210-026-05400-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,8]]},"references-count":52,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["5400"],"URL":"https:\/\/doi.org\/10.1007\/s00210-026-05400-y","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,8]]},"assertion":[{"value":"16 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}