{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T04:01:07Z","timestamp":1784779267809,"version":"3.55.0"},"reference-count":150,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Naunyn-Schmiedeberg's Arch Pharmacol"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1007\/s00210-026-05424-4","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T02:50:53Z","timestamp":1778554253000},"page":"16451-16474","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Protective effect of docosahexaenoic acid (DHA) against prenatal cytarabine exposure-induced developmental toxicity in SD rat"],"prefix":"10.1007","volume":"399","author":[{"given":"Kavitha N.","family":"Chilaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sai Nithish","family":"Nimmalapudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramanachary","family":"Namoju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,12]]},"reference":[{"key":"5424_CR1","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/s00404-022-06533-0","volume":"307","author":"MA Abdelrahman","year":"2023","unstructured":"Abdelrahman MA, Osama H, Saeed H, Madney YM, Harb HS, Abdelrahim MEA (2023) Impact of n-3 polyunsaturated fatty acid intake in pregnancy on maternal health and birth outcomes: systematic review and meta-analysis from randomized controlled trails. Arch Gynecol Obstet 307:249\u2013262. https:\/\/doi.org\/10.1007\/s00404-022-06533-0","journal-title":"Arch Gynecol Obstet"},{"issue":"5","key":"5424_CR2","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/s0145-2126(02)00182-0","volume":"27","author":"R Ali","year":"2003","unstructured":"Ali R, Ozkalemka\u015f F, Oz\u00e7elik T, Ozkocaman V, Ozan U, Kimya Y, Tunali A (2003) Maternal and fetal outcomes in pregnancy complicated with acute leukemia: a single institutional experience with 10 pregnancies at 16 years. Leuk Res 27(5):381\u2013385. https:\/\/doi.org\/10.1016\/s0145-2126(02)00182-0","journal-title":"Leuk Res"},{"issue":"4","key":"5424_CR3","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1111\/bjh.13554","volume":"170","author":"S Ali","year":"2015","unstructured":"Ali S, Jones GL, Culligan DJ, Marsden PJ, Russell N, Embleton ND, Craddock C, British Committee for Standards in Haematology (2015) Guidelines for the diagnosis and management of acute myeloid leukaemia in pregnancy. Br J Haematol 170(4):487\u2013495. https:\/\/doi.org\/10.1111\/bjh.13554","journal-title":"Br J Haematol"},{"key":"5424_CR4","doi-asserted-by":"publisher","DOI":"10.3390\/md22100446","volume":"22","author":"Z Ali","year":"2024","unstructured":"Ali Z, Al-Ghouti MA, Abou-Saleh H, Rahman MM (2024) Unraveling the omega-3 puzzle: navigating challenges and innovations for bone health and healthy aging. Mar Drugs 22:446. https:\/\/doi.org\/10.3390\/md22100446","journal-title":"Mar Drugs"},{"key":"5424_CR5","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1002\/tera.1420200208","volume":"20","author":"V Aliverti","year":"1979","unstructured":"Aliverti V, Bonanomi L, Giavini E, Leone VG, Mariani L (1979) The extent of fetal ossification as an index of delayed development in teratogenic studies on the rat. Teratology 20:237\u2013242. https:\/\/doi.org\/10.1002\/tera.1420200208","journal-title":"Teratology"},{"key":"5424_CR6","doi-asserted-by":"publisher","first-page":"6348","DOI":"10.5897\/AJB10.044","volume":"10","author":"HRA Ashtiani","year":"2011","unstructured":"Ashtiani HRA, Bakhshandi AK, Rahbar M, Mirzaei A, Malekpour A, Rastegar H (2011) Glutathione, cell proliferation and differentiation. Afr J Biotechnol 10:6348\u20136363. https:\/\/doi.org\/10.5897\/AJB10.044","journal-title":"Afr J Biotechnol"},{"key":"5424_CR7","doi-asserted-by":"publisher","unstructured":"Baker WJ, Royer GL Jr, Weiss RB (1991) Cytarabine and neurologic toxicity. J Clin Oncol 9:679\u2013693. https:\/\/doi.org\/10.1200\/JCO.1991.9.4.67","DOI":"10.1200\/JCO.1991.9.4.67"},{"issue":"6","key":"5424_CR8","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1007\/s12975-013-0282-1","volume":"4","author":"G Begum","year":"2013","unstructured":"Begum G, Harvey L, Dixon CE, Sun D (2013) ER stress and effects of DHA as an ER stress inhibitor. Transl Stroke Res 4(6):635\u2013642. https:\/\/doi.org\/10.1007\/s12975-013-0282-1","journal-title":"Transl Stroke Res"},{"key":"5424_CR9","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.nutres.2024.06.008","volume":"128","author":"K Bilgundi","year":"2024","unstructured":"Bilgundi K, Viswanatha GL, Purushottam KM, John J, Kamath AP, Kishore A, Nayak PG, Nandakumar K (2024) Docosahexaenoic acid and pregnancy: a systematic review and meta-analysis of the association with improved maternal and fetal health. Nutr Res 128:82\u201393. https:\/\/doi.org\/10.1016\/j.nutres.2024.06.008","journal-title":"Nutr Res"},{"key":"5424_CR10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2023.109359","volume":"118","author":"Q Bo","year":"2023","unstructured":"Bo Q, Xie Y, Lin Q, Fu L, Hu C, Zhang Z, Meng Q, Xu F, Wang G, Miao Z, Wang H, Xu D (2023) Docosahexaenoic acid protects against lipopolysaccharide-induced fetal growth restriction via inducing the ubiquitination and degradation of NF-\u03baB p65 in placental trophoblasts. J Nutr Biochem 118:109359. https:\/\/doi.org\/10.1016\/j.jnutbio.2023.109359","journal-title":"J Nutr Biochem"},{"key":"5424_CR11","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12061283","volume":"12","author":"SM Borgonovi","year":"2023","unstructured":"Borgonovi SM, Iametti S, Di Nunzio M (2023) Docosahexaenoic acid as master regulator of cellular antioxidant defenses: a systematic review. Antioxidants 12:1283. https:\/\/doi.org\/10.3390\/antiox12061283","journal-title":"Antioxidants"},{"issue":"3","key":"5424_CR12","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1111\/imj.16651","volume":"55","author":"L Cassidy","year":"2025","unstructured":"Cassidy L, Shand A, Said JM, Hobbs K, Kidson-Gerber G, Belinda C, Cutts B, Heath S, Anazodo A, King K, Palfreyman E, Di Ciaccio P, Mills G, Tang C, Gangatharan S, Johnston A, Morris K, Hamad N (2025) Haematological malignancies during pregnancy: a systematic review of necessary services in the Australian context. Intern Med J 55(3):393\u2013406. https:\/\/doi.org\/10.1111\/imj.16651","journal-title":"Intern Med J"},{"issue":"2","key":"5424_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2023.101251","volume":"6","author":"I Cetin","year":"2024","unstructured":"Cetin I, Carlson SE, Burden C, da Fonseca EB, di Renzo GC, Hadjipanayis A, Harris WS, Kumar KR, Olsen SF, Mader S, McAuliffe FM, Muhlhausler B, Oken E, Poon LC, Poston L, Ramakrishnan U, Roehr CC, Savona-Ventura C, Smuts CM, Sotiriadis A, Su K-P, Tribe RM, Vannice G, Koletzko B (2024) Omega-3 fatty acid supply in pregnancy for risk reduction of preterm and early preterm birth. Am J Obstet Gynecol MFM 6(2):101251. https:\/\/doi.org\/10.1016\/j.ajogmf.2023.101251","journal-title":"Am J Obstet Gynecol MFM"},{"issue":"2","key":"5424_CR14","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1207\/S15327914NC4402_09","volume":"44","author":"MC Cha","year":"2002","unstructured":"Cha MC, Meckling KA, Stewart C (2002) Dietary docosahexaenoic acid levels influence the outcome of arabinosylcytosine chemotherapy in L1210 leukemic mice. Nutr Cancer 44(2):176\u2013181. https:\/\/doi.org\/10.1207\/S15327914NC4402_09","journal-title":"Nutr Cancer"},{"key":"5424_CR15","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2210-5-7","volume":"5","author":"MC Cha","year":"2005","unstructured":"Cha MC, Lin A, Meckling KA (2005) Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity. BMC Pharmacol 5:7. https:\/\/doi.org\/10.1186\/1471-2210-5-7","journal-title":"BMC Pharmacol"},{"issue":"1","key":"5424_CR16","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1177\/1060028014552516","volume":"49","author":"A Chang","year":"2015","unstructured":"Chang A, Patel S (2015) Treatment of acute myeloid leukemia during pregnancy. Ann Pharmacother 49(1):48\u201368. https:\/\/doi.org\/10.1177\/1060028014552516","journal-title":"Ann Pharmacother"},{"key":"5424_CR17","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1016\/00062952(68)90058-0","volume":"17","author":"S Chaube","year":"1968","unstructured":"Chaube S, Kreis W, Uchida K, Murphy ML (1968) The teratogenic effect of 1-beta-D-arabinofuranosylcytosine in the rat, protection by deoxycytidine. Biochem Pharmacol 17:1213\u20131216. https:\/\/doi.org\/10.1016\/00062952(68)90058-0","journal-title":"Biochem Pharmacol"},{"key":"5424_CR18","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.1021\/ac60119a033","volume":"28","author":"PS Chen","year":"1956","unstructured":"Chen PS, Toribara TY, Huber W (1956) Microdetermination of phosphorus. Anal Chem 28:1756\u20131758. https:\/\/doi.org\/10.1021\/ac60119a033","journal-title":"Anal Chem"},{"key":"5424_CR19","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1177\/00099228241250139","volume":"64","author":"YQ Chi","year":"2025","unstructured":"Chi YQ, Yao Y, Zhang WH, Zhang ZH, Wang YH, Hao W (2025) Docosahexaenoic acid supplementation for neonatal hyperbilirubinemia: a double-blind, randomized clinical trial. Clin Pediatr (Phila) 64:48\u201354. https:\/\/doi.org\/10.1177\/00099228241250139","journal-title":"Clin Pediatr (Phila)"},{"key":"5424_CR20","first-page":"215","volume":"27","author":"H Chiang","year":"1993","unstructured":"Chiang H (1993) [VDT pulse magnetic field enhances teratogenic effect of Ara-C in mice]. Zhonghua Yu Fang Yi Xue Za Zhi 27:215\u2013217","journal-title":"Zhonghua Yu Fang Yi Xue Za Zhi"},{"issue":"1","key":"5424_CR21","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1002\/bem.2250160113","volume":"16","author":"H Chiang","year":"1995","unstructured":"Chiang H, Wu RY, Shao BJ, Fu YD, Yao GD, Lu DJ (1995) Pulsed magnetic field from video display terminals enhances teratogenic effects of cytosine arabinoside in mice. Bioelectromagnetics 16(1):70\u201374. https:\/\/doi.org\/10.1002\/bem.2250160113","journal-title":"Bioelectromagnetics"},{"key":"5424_CR22","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/0890-6238(96)00024-X","volume":"10","author":"K Chiba","year":"1996","unstructured":"Chiba K, Ishikawa H, Rahman ME, Endo A (1996) Neonatal mouse hip joint and hindlimb anomalies induced by prenatal exposure to Ara-C. Reprod Toxicol 10:215\u2013219. https:\/\/doi.org\/10.1016\/0890-6238(96)00024-X","journal-title":"Reprod Toxicol"},{"key":"5424_CR23","doi-asserted-by":"publisher","first-page":"4035","DOI":"10.1007\/s00210-023-02852-4","volume":"397","author":"KN Chilaka","year":"2024","unstructured":"Chilaka KN, Namoju R (2024) Maternal supplementation of alpha-lipoic acid ameliorates prenatal cytarabine-induced mutilation in reproductive development and function in F1 male adult rats. Naunyn Schmiedebergs Arch Pharmacol 397:4035\u20134053. https:\/\/doi.org\/10.1007\/s00210-023-02852-4","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"3","key":"5424_CR24","doi-asserted-by":"publisher","first-page":"235","DOI":"10.3892\/etm.2022.11160","volume":"23","author":"SE Cifuentes-Mendiola","year":"2022","unstructured":"Cifuentes-Mendiola SE, Moreno-Fierros L, Gonz\u00e1lez-Alva P, Garc\u00eda-Hern\u00e1ndez AL (2022) Docosahexaenoic acid improves altered mineralization proteins, the decreased quality of hydroxyapatite crystals and suppresses oxidative stress induced by high glucose. Exp Ther Med 23:235. https:\/\/doi.org\/10.3892\/etm.2022.11160","journal-title":"Exp Ther Med"},{"issue":"5","key":"5424_CR25","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1055\/s-2007-993946","volume":"15","author":"HL Claahsen","year":"1998","unstructured":"Claahsen HL, Semmekrot BA, van Dongen PW, Mattijssen V (1998) Successful fetal outcome after exposure to idarubicin and cytosine-arabinoside during the second trimester of pregnancy- -a case report. Am J Perinatol 15(5):295\u2013297. https:\/\/doi.org\/10.1055\/s-2007-993946","journal-title":"Am J Perinatol"},{"issue":"9","key":"5424_CR26","doi-asserted-by":"publisher","DOI":"10.3390\/nu13093075","volume":"13","author":"A Daher-Abdi","year":"2021","unstructured":"Daher-Abdi A, Olvera Hern\u00e1ndez S, Reyes Castro LA, Mezo-Gonz\u00e1lez CE, Croyal M, Garc\u00eda-Santill\u00e1n JA, Ouguerram K, Zambrano E, Bola\u00f1os-Jim\u00e9nez F (2021) Maternal DHA supplementation during pregnancy and lactation in the rat protects the offspring against high-calorie diet-induced hepatic steatosis. Nutrients 13(9):3075. https:\/\/doi.org\/10.3390\/nu13093075","journal-title":"Nutrients"},{"issue":"8","key":"5424_CR27","doi-asserted-by":"publisher","first-page":"2034","DOI":"10.1177\/1078155220915764","volume":"26","author":"CC Dang","year":"2020","unstructured":"Dang CC, Guan YK, Lau NS, Chan SY (2020) Two successful deliveries of healthy children by a young woman diagnosed and treated during induction and relapsed therapy for acute promyelocytic leukemia. J Oncol Pharm Pract 26(8):2034\u20132037. https:\/\/doi.org\/10.1177\/1078155220915764","journal-title":"J Oncol Pharm Pract"},{"key":"5424_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2024.101358","volume":"6","author":"EA DeFranco","year":"2024","unstructured":"DeFranco EA, Valentine CJ, Carlson SE, Sands SA, Gajewski BJ (2024) Racial disparity in efficacy of docosahexaenoic acid supplementation for prevention of preterm birth: secondary analysis from a randomized, double-blind trial. Am J Obstet Gynecol MFM 6:101358. https:\/\/doi.org\/10.1016\/j.ajogmf.2024.101358","journal-title":"Am J Obstet Gynecol MFM"},{"key":"5424_CR29","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1002\/bdr2.1350","volume":"110","author":"JM DeSesso","year":"2018","unstructured":"DeSesso JM, Scialli AR (2018) Bone development in laboratory mammals used in developmental toxicity studies. Birth Defects Res 110:1157\u20131187. https:\/\/doi.org\/10.1002\/bdr2.1350","journal-title":"Birth Defects Res"},{"key":"5424_CR30","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13050966","volume":"13","author":"R Di Francia","year":"2021","unstructured":"Di Francia R, Crisci S, De Monaco A, Cafiero C, Re A, Iaccarino G, De Filippi R, Frigeri F, Corazzelli G, Micera A, Pinto A (2021) Response and toxicity to cytarabine therapy in leukemia and lymphoma: from dose puzzle to pharmacogenomic biomarkers. Cancers (Basel) 13:966. https:\/\/doi.org\/10.3390\/cancers13050966","journal-title":"Cancers (Basel)"},{"key":"5424_CR31","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1016\/j.freeradbiomed.2015.09.023","volume":"89","author":"P Diaz-Vivancos","year":"2015","unstructured":"Diaz-Vivancos P, de Simone A, Kiddle G, Foyer CH (2015) Glutathione-linking cell proliferation to oxidative stress. Free Radic Biol Med 89:1154\u20131164. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2015.09.023","journal-title":"Free Radic Biol Med"},{"issue":"3","key":"5424_CR32","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1111\/j.1365-2257.2006.00781.x","volume":"28","author":"I Dilek","year":"2006","unstructured":"Dilek I, Topcu N, Demir C, Bay A, Uzun K, Gul A, Faik Oner A, Ugras S (2006) Hematological malignancy and pregnancy: a single-institution experience of 21 cases. Clin Lab Haematol 28(3):170\u2013176. https:\/\/doi.org\/10.1111\/j.1365-2257.2006.00781.x","journal-title":"Clin Lab Haematol"},{"issue":"2","key":"5424_CR33","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1007\/s00404-024-07402-8","volume":"310","author":"J Ding","year":"2024","unstructured":"Ding J, Xiao Y, Fu J, Liu G, Huang S, Mo X (2024) Pregnancy and neonatal outcomes in 25 pregnant women diagnosed with new-onset acute myeloid leukemia during pregnancy. Arch Gynecol Obstet 310(2):783\u2013791. https:\/\/doi.org\/10.1007\/s00404-024-07402-8","journal-title":"Arch Gynecol Obstet"},{"key":"5424_CR34","doi-asserted-by":"publisher","first-page":"209","DOI":"10.11138\/ccmbm\/2017.14.1.209","volume":"14","author":"V Domazetovic","year":"2017","unstructured":"Domazetovic V, Marcucci G, Iantomasi T, Brandi ML, Vincenzini MT (2017) Oxidative stress in bone remodeling: role of antioxidants. Clin Cases Miner Bone Metab 14:209\u2013216. https:\/\/doi.org\/10.11138\/ccmbm\/2017.14.1.209","journal-title":"Clin Cases Miner Bone Metab"},{"key":"5424_CR35","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/0003-9861(59)90090-6","volume":"82","author":"GL Ellman","year":"1959","unstructured":"Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82:70\u201377. https:\/\/doi.org\/10.1016\/0003-9861(59)90090-6","journal-title":"Arch Biochem Biophys"},{"key":"5424_CR36","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1002\/tcm.1770070505","volume":"7","author":"A Endo","year":"1987","unstructured":"Endo A, Sakai N, Ohwada K (1987) Analysis of diurnal difference in teratogen (Ara-C) susceptibility in mouse embryos by a progressive phase-shift method. Teratog Carcinog Mutagen 7:475\u2013482. https:\/\/doi.org\/10.1002\/tcm.1770070505","journal-title":"Teratog Carcinog Mutagen"},{"key":"5424_CR37","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1111\/j.1439-0264.1996.tb00090.x","volume":"25","author":"D Erdo\u011fan","year":"1996","unstructured":"Erdo\u011fan D, Kadio\u011flu D, Peker T (1996) Demonstration of congenital anomalies in the joints of the forelimbs and hindlimbs caused by several pharmacological agents. Anat Histol Embryol 25:263\u2013267. https:\/\/doi.org\/10.1111\/j.1439-0264.1996.tb00090.x","journal-title":"Anat Histol Embryol"},{"key":"5424_CR38","doi-asserted-by":"publisher","unstructured":"Eastwood-Wilshere N, Turner J, Oliveira N, Morton A (2019) Cancer in pregnancy.\u00a0Asia Pac J Clin Oncol\u00a015:296\u2013308. https:\/\/doi.org\/10.1111\/ajco.13235","DOI":"10.1111\/ajco.13235"},{"key":"5424_CR39","first-page":"321","volume":"53","author":"RA Fadel","year":"2012","unstructured":"Fadel RA, Sequeira RP, Abu-Hijleh MF, Obeidat M, Salem AH (2012) Effect of prenatal administration of therapeutic doses of topiramate on ossification of ribs and vertebrae in rat fetuses. Rom J Morphol Embryol 53:321\u2013327","journal-title":"Rom J Morphol Embryol"},{"issue":"3","key":"5424_CR40","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1089\/ars.2010.3750","volume":"16","author":"Z Feng","year":"2012","unstructured":"Feng Z, Zou X, Jia H, Li X, Zhu Z, Liu X, Bucheli P, Ballevre O, Hou Y, Zhang W, Wang J, Chen Y, Liu J (2012) Maternal docosahexaenoic acid feeding protects against impairment of learning and memory and oxidative stress in prenatally stressed rats: possible role of neuronal mitochondria metabolism. Antioxid Redox Signal 16(3):275\u2013289. https:\/\/doi.org\/10.1089\/ars.2010.3750","journal-title":"Antioxid Redox Signal"},{"key":"5424_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2019.e02672","volume":"5","author":"AM Fikri","year":"2019","unstructured":"Fikri AM, Sulaeman A, Handharyani E, Marliyati SA, Fahrudin M (2019) The effect of propolis administration on fetal development. Heliyon 5:e02672. https:\/\/doi.org\/10.1016\/j.heliyon.2019.e02672","journal-title":"Heliyon"},{"issue":"1","key":"5424_CR42","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1186\/s12885-017-3436-9","volume":"17","author":"NS Fracchiolla","year":"2017","unstructured":"Fracchiolla NS, Scium\u00e8 M, Dambrosi F, Guidotti F, Ossola MW, Chidini G, Gianelli U, Merlo D, Cortelezzi A (2017) Acute myeloid leukemia and pregnancy: clinical experience from a single center and a review of the literature. BMC Cancer 17(1):442. https:\/\/doi.org\/10.1186\/s12885-017-3436-9","journal-title":"BMC Cancer"},{"key":"5424_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1293\/tox.2018-0042","volume":"32","author":"S Furukawa","year":"2019","unstructured":"Furukawa S, Tsuji N, Sugiyama A (2019) Morphology and physiology of rat placenta for toxicological evaluation. J Toxicol Pathol 32:1\u201317. https:\/\/doi.org\/10.1293\/tox.2018-0042","journal-title":"J Toxicol Pathol"},{"key":"5424_CR44","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.jnutbio.2016.07.003","volume":"35","author":"J Gao","year":"2016","unstructured":"Gao J, Wu H, Cao Y, Liang S, Sun C, Wang P, Wang J, Sun H, Wu L (2016) Maternal DHA supplementation protects rat offspring against impairment of learning and memory following prenatal exposure to valproic acid. J Nutr Biochem 35:87\u201395. https:\/\/doi.org\/10.1016\/j.jnutbio.2016.07.003","journal-title":"J Nutr Biochem"},{"key":"5424_CR45","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.112871","volume":"140","author":"A Gezer","year":"2024","unstructured":"Gezer A, \u00d6zkaraca M, \u00dcst\u00fcnda\u011f H, Soydan M, Alkano\u011flu \u00d6, Bedir G (2024) Docosahexaenoic acid eliminates endoplasmic reticulum stress and inflammatory pathways in diabetic rat keratopathy. Int Immunopharmacol 140:112871. https:\/\/doi.org\/10.1016\/j.intimp.2024.112871","journal-title":"Int Immunopharmacol"},{"key":"5424_CR46","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1002\/tera.1420350106","volume":"35","author":"T Goto","year":"1987","unstructured":"Goto T, Endo A (1987) Dose- and stage-related sex difference in the incidence of cytosine arabinoside induced digit anomalies in the mouse fetus. Teratology 35:35\u201340. https:\/\/doi.org\/10.1002\/tera.1420350106","journal-title":"Teratology"},{"key":"5424_CR47","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110306","volume":"128","author":"T Gui","year":"2020","unstructured":"Gui T, Li Y, Zhang S, Zhang N, Sun Y, Liu F, Chen Q, Gai Z (2020) Docosahexaenoic acid protects against palmitate-induced mitochondrial dysfunction in diabetic cardiomyopathy. Biomed Pharmacother 128:110306. https:\/\/doi.org\/10.1016\/j.biopha.2020.110306","journal-title":"Biomed Pharmacother"},{"key":"5424_CR48","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.2174\/1871520615666160504093652","volume":"16","author":"DC Guzm\u00e1n","year":"2016","unstructured":"Guzm\u00e1n DC, Brizuela NO, Herrera MO, Olgu\u00edn HJ, Garc\u00eda EH, Peraza AV, Mej\u00eda GB (2016) Oleic acid protects against oxidative stress exacerbated by cytarabine and doxorubicin in rat brain. Anticancer Agents Med Chem 16:1491\u20131495. https:\/\/doi.org\/10.2174\/1871520615666160504093652","journal-title":"Anticancer Agents Med Chem"},{"key":"5424_CR49","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1002\/tera.1420050220","volume":"5","author":"JJ Hallett","year":"1972","unstructured":"Hallett JJ, Ritter EJ, Scott WJ, Wilson JG (1972) Isozyme patterns in limb buds of cytosine arabinoside treated rat embryos. Teratology 5:247\u2013270. https:\/\/doi.org\/10.1002\/tera.1420050220","journal-title":"Teratology"},{"key":"5424_CR50","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1002\/bdrc.20085","volume":"78","author":"JM Hansen","year":"2006","unstructured":"Hansen JM (2006) Oxidative stress as a mechanism of teratogenesis. Birth Defects Res C Embryo Today Rev 78:293\u2013307. https:\/\/doi.org\/10.1002\/bdrc.20085","journal-title":"Birth Defects Res C Embryo Today Rev"},{"key":"5424_CR51","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1080\/07388551.2016.1207153","volume":"37","author":"M Hashimoto","year":"2017","unstructured":"Hashimoto M, Hossain S, Al Mamun A, Matsuzaki K, Arai H (2017) Docosahexaenoic acid: one molecule diverse functions. Crit Rev Biotechnol 37:579\u2013597. https:\/\/doi.org\/10.1080\/07388551.2016.1207153","journal-title":"Crit Rev Biotechnol"},{"key":"5424_CR52","doi-asserted-by":"publisher","first-page":"194","DOI":"10.20960\/nh.1245","volume":"35","author":"E Hern\u00e1ndez Garc\u00eda","year":"2018","unstructured":"Hern\u00e1ndez Garc\u00eda E, Osnaya Brizuela N, Valenzuela Peraza A, Calder\u00f3n Guzm\u00e1n D, Ortiz Herrera M, Ju\u00e1rez Olgu\u00edn H, Barrag\u00e1n Mej\u00eda G, Santamar\u00eda Del \u00c1ngel D, Rojas Ochoa A (2018) Biochemical and histological changes produced by sweeteners and cytarabine in the brain of young rats. Nutr Hosp 35:194\u2013200. https:\/\/doi.org\/10.20960\/nh.1245","journal-title":"Nutr Hosp"},{"issue":"3","key":"5424_CR53","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1080\/10428194.2017.1347651","volume":"59","author":"NA Horowitz","year":"2018","unstructured":"Horowitz NA, Henig I, Henig O, Benyamini N, Vidal L, Avivi I (2018) Acute myeloid leukemia during pregnancy: a systematic review and meta-analysis. Leuk Lymphoma 59(3):610\u2013616. https:\/\/doi.org\/10.1080\/10428194.2017.1347651","journal-title":"Leuk Lymphoma"},{"key":"5424_CR54","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2021.147708","volume":"1774","author":"L Huang","year":"2022","unstructured":"Huang L, Zhou Y, Gou ZX, Zhang F, Lu LQ (2022) Docosahexaenoic acid reduces hypoglycemia-induced neuronal necroptosis via the peroxisome proliferator-activated receptor \u03b3\/nuclear factor-\u03baB pathway. Brain Res 1774:147708. https:\/\/doi.org\/10.1016\/j.brainres.2021.147708","journal-title":"Brain Res"},{"key":"5424_CR55","doi-asserted-by":"publisher","first-page":"1","DOI":"10.15761\/JPR.1000103","volume":"1","author":"C Hubinont","year":"2017","unstructured":"Hubinont C, Savoye T (2017) Maternal and fetal benefits of DHA supplementation during pregnancy. J Pregnancy Reprod 1:1\u20137. https:\/\/doi.org\/10.15761\/JPR.1000103","journal-title":"J Pregnancy Reprod"},{"key":"5424_CR56","doi-asserted-by":"publisher","first-page":"4987","DOI":"10.1016\/j.sjbs.2021.05.058","volume":"28","author":"W Jiang","year":"2021","unstructured":"Jiang W, Wan L, Chen P, Lu W (2021) Docosahexaenoic acid activates the Nrf2 signaling pathway to alleviate impairment of spleen cellular immunity in intrauterine growth restricted rat pups. Saudi J Biol Sci 28:4987\u20134993. https:\/\/doi.org\/10.1016\/j.sjbs.2021.05.058","journal-title":"Saudi J Biol Sci"},{"key":"5424_CR57","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-023-04239-8","volume":"21","author":"Y Jiang","year":"2023","unstructured":"Jiang Y, Chen Y, Wei L, Zhang H, Zhang J, Zhou X, Zhu S, Du Y, Su R, Fang C, Ding W, Feng L (2023) DHA supplementation and pregnancy complications. J Transl Med 21:394. https:\/\/doi.org\/10.1186\/s12967-023-04239-8","journal-title":"J Transl Med"},{"key":"5424_CR58","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1095\/biolreprod.112.103754","volume":"88","author":"ML Jones","year":"2013","unstructured":"Jones ML, Mark PJ, Mori TA, Keelan JA, Waddell BJ (2013) Maternal dietary omega-3 fatty acid supplementation reduces placental oxidative stress and increases fetal and placental growth in the rat. Biol Reprod 88:37. https:\/\/doi.org\/10.1095\/biolreprod.112.103754","journal-title":"Biol Reprod"},{"key":"5424_CR59","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1002\/bdr2.1614","volume":"112","author":"FR Kapourchali","year":"2020","unstructured":"Kapourchali FR, Louis XL, Eskin MNA, Suh M (2020) A pilot study on the effect of early provision of dietary docosahexaenoic acid on testis development, functions, and sperm quality in rats exposed to prenatal ethanol. Birth Defects Res 112:93\u2013104. https:\/\/doi.org\/10.1002\/bdr2.1614","journal-title":"Birth Defects Res"},{"key":"5424_CR60","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1002\/tera.1420160111","volume":"16","author":"Y Kasubuchi","year":"1977","unstructured":"Kasubuchi Y, Wakaizumi S, Shimada M, Kusunoki T (1977) Cytosine arabinoside-induce transplacental dysgenetic hydrocephalus in mice. Teratology 16:63\u201370. https:\/\/doi.org\/10.1002\/tera.1420160111","journal-title":"Teratology"},{"key":"5424_CR61","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.cellsig.2016.11.007","volume":"29","author":"HJ Kim","year":"2017","unstructured":"Kim HJ, Ohk B, Yoon HJ, Kang WY, Seong SJ, Kim SY, Yoon YR (2017) Docosahexaenoic acid signaling attenuates the proliferation and differentiation of bone marrow-derived osteoclast precursors and promotes apoptosis in mature osteoclasts. Cell Signal 29:226\u2013232. https:\/\/doi.org\/10.1016\/j.cellsig.2016.11.007","journal-title":"Cell Signal"},{"key":"5424_CR62","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2023.102666","volume":"62","author":"SH Kim","year":"2023","unstructured":"Kim SH, Lee SE, Kim SJ, Fang X, Hur J, Sozen E, \u00d6zer NK, Kim KP, Surh YJ (2023) Protective effects of an electrophilic metabolite of docosahexaenoic acid on UVB-induced oxidative cell death, dermatitis, and carcinogenesis. Redox Biol 62:102666. https:\/\/doi.org\/10.1016\/j.redox.2023.102666","journal-title":"Redox Biol"},{"key":"5424_CR63","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1002\/tera.1420180111","volume":"18","author":"DM Kochhar","year":"1978","unstructured":"Kochhar DM, Penner JD, McDay JA (1978) Limb development in mouse embryos, II, reduction defects, cytotoxicity and inhibition of DNA synthesis produced by cytosine arabinoside. Teratology 18:71\u201392. https:\/\/doi.org\/10.1002\/tera.1420180111","journal-title":"Teratology"},{"key":"5424_CR64","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e30165","volume":"10","author":"MJ Koech","year":"2024","unstructured":"Koech MJ, Mwangi J, Kithaka B, Kimaru S, Kusu N, Munyi L, Chahonyo S, Makokha F (2024) Effects of stigma on quality of life of cancer survivors: preliminary evidence from a survivorship programme in Kenya. Heliyon 10:e30165. https:\/\/doi.org\/10.1016\/j.heliyon.2024.e30165","journal-title":"Heliyon"},{"key":"5424_CR65","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0003-9861(78)90479-4","volume":"186","author":"Y Kono","year":"1978","unstructured":"Kono Y (1978) Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. Arch Biochem Biophys 186:189\u2013195. https:\/\/doi.org\/10.1016\/0003-9861(78)90479-4","journal-title":"Arch Biochem Biophys"},{"key":"5424_CR66","doi-asserted-by":"publisher","unstructured":"Laforgia N, Di Mauro A, Favia Guarnieri G, Varvara D, De Cosmo L, Panza R, Capozza M, Baldassarre ME, Resta N (2018) The role of oxidative stress in the pathomechanism of congenital malformations. Oxid Med Cell Longev 7404082. https:\/\/doi.org\/10.1155\/2018\/7404082","DOI":"10.1155\/2018\/7404082"},{"issue":"8","key":"5424_CR67","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2024.12.019","volume":"60","author":"LR Lee","year":"2025","unstructured":"Lee LR, Guillotin B, Rahni R, Hutchison C, Desvoyes B, Gutierrez C, Birnbaum KD (2025) Glutathione accelerates the cell cycle and cellular reprogramming in plant regeneration. Dev Cell S1534-5807(24)00758-5. https:\/\/doi.org\/10.1016\/j.devcel.2024.12.019","journal-title":"Dev Cell"},{"key":"5424_CR68","doi-asserted-by":"publisher","unstructured":"Li Y, Seifert MF, Lim SY, Salem N Jr, Watkins BA (2010) Bone mineral content is positively correlated to n-3 fatty acids in the femur of growing rats. Br J Nutr 104:674\u2013685. https:\/\/doi.org\/10.1017\/S0007114510001133","DOI":"10.1017\/S0007114510001133"},{"key":"5424_CR69","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1021\/acs.jafc.0c07751","volume":"69","author":"G Li","year":"2021","unstructured":"Li G, Li Y, Xiao B, Cui D, Lin Y, Zeng J, Li J, Cao MJ, Liu J (2021) Antioxidant activity of docosahexaenoic acid (DHA) and its regulatory roles in mitochondria. J Agric Food Chem 69:1647\u20131655. https:\/\/doi.org\/10.1021\/acs.jafc.0c07751","journal-title":"J Agric Food Chem"},{"key":"5424_CR70","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"OH Lowry","year":"1951","unstructured":"Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265\u2013275","journal-title":"J Biol Chem"},{"key":"5424_CR71","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2023.122613","volume":"337","author":"AX Lu","year":"2023","unstructured":"Lu AX, Lin Y, Li J, Liu JX, Yan CH, Zhang L (2023) Effects of food-borne docosahexaenoic acid supplementation on bone lead mobilisation, mitochondrial function and serum metabolomics in pre-pregnancy lead-exposed lactating rats. Environ Pollut 337:122613. https:\/\/doi.org\/10.1016\/j.envpol.2023.122613","journal-title":"Environ Pollut"},{"key":"5424_CR72","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.929690","volume":"13","author":"J Ma","year":"2023","unstructured":"Ma J, Kitaura H, Ogawa S, Ohori F, Noguchi T, Marahleh A, Nara Y, Pramusita A, Kinjo R, Kanou K, Kishikawa A, Ichimura A, Mizoguchi I (2023) Docosahexaenoic acid inhibits TNF-\u03b1-induced osteoclast formation and orthodontic tooth movement through GPR120. Front Immunol 13:929690. https:\/\/doi.org\/10.3389\/fimmu.2022.929690","journal-title":"Front Immunol"},{"key":"5424_CR73","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1182\/blood-2017-04-777722","volume":"130","author":"KN Magina","year":"2017","unstructured":"Magina KN, Pregartner G, Zebisch A, W\u00f6lfler A, Neumeister P, Greinix HT, Berghold A, Sill H (2017) Cytarabine dose in the consolidation treatment of AML: a systematic review and meta-analysis. Blood 130:946\u2013948. https:\/\/doi.org\/10.1182\/blood-2017-04-777722","journal-title":"Blood"},{"key":"5424_CR74","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-018-0357-7","volume":"16","author":"V Maillard","year":"2018","unstructured":"Maillard V, Desmarchais A, Durcin M, Uzbekova S, Elis S (2018) Docosahexaenoic acid (DHA) effects on proliferation and steroidogenesis of bovine granulosa cells. Reprod Biol Endocrinol 16:40. https:\/\/doi.org\/10.1186\/s12958-018-0357-7","journal-title":"Reprod Biol Endocrinol"},{"key":"5424_CR75","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1007\/BF02615104","volume":"13","author":"JM Manson","year":"1977","unstructured":"Manson JM, Dourson ML, Smith CC (1977) Effects of cytosine arabinoside on in vivo and in vitro mouse limb development. In Vitro 13:434\u2013442. https:\/\/doi.org\/10.1007\/BF02615104","journal-title":"In Vitro"},{"key":"5424_CR76","doi-asserted-by":"publisher","first-page":"20416","DOI":"10.1074\/jbc.M609582200","volume":"282","author":"J Markovic","year":"2007","unstructured":"Markovic J, Borr\u00e1s C, Ortega A, Sastre J, Vi\u00f1a J, Pallard\u00f3 FV (2007) Glutathione is recruited into the nucleus in early phases of cell proliferation. J Biol Chem 282:20416\u201320424. https:\/\/doi.org\/10.1074\/jbc.M609582200","journal-title":"J Biol Chem"},{"key":"5424_CR77","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/358375","author":"L Marseglia","year":"2014","unstructured":"Marseglia L, D\u2019Angelo G, Manti S, Arrigo T, Barberi I, Reiter RJ, Gitto E (2014) Oxidative stress-mediated aging during the fetal and perinatal periods. Oxid Med Cell Longev. https:\/\/doi.org\/10.1155\/2014\/358375","journal-title":"Oxid Med Cell Longev"},{"issue":"1","key":"5424_CR78","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-49362-z","volume":"9","author":"LT Meital","year":"2019","unstructured":"Meital LT, Windsor MT, Perissiou M, Schulze K, Magee R, Kuballa A, Golledge J, Bailey TG, Askew CD, Russell FD (2019) Omega-3 fatty acids decrease oxidative stress and inflammation in macrophages from patients with small abdominal aortic aneurysm. Sci Rep 9(1):12978. https:\/\/doi.org\/10.1038\/s41598-019-49362-z","journal-title":"Sci Rep"},{"key":"5424_CR79","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1002\/tera.1055","volume":"64","author":"E Menegola","year":"2001","unstructured":"Menegola E, Broccia ML, Giavini E (2001) Atlas of rat fetal skeleton double stained for bone and cartilage. Teratology 64:125\u2013133. https:\/\/doi.org\/10.1002\/tera.1055","journal-title":"Teratology"},{"key":"5424_CR80","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1182\/blood-2013-08-283580","volume":"123","author":"D Milojkovic","year":"2014","unstructured":"Milojkovic D, Apperley JF (2014) How I treat leukemia during pregnancy. Blood 123:974\u2013984. https:\/\/doi.org\/10.1182\/blood-2013-08-283580","journal-title":"Blood"},{"issue":"14","key":"5424_CR81","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241411691","volume":"24","author":"M Montecillo-Aguado","year":"2023","unstructured":"Montecillo-Aguado M, Tirado-Rodriguez B, Huerta-Yepez S (2023) The involvement of polyunsaturated fatty acids in apoptosis mechanisms and their implications in cancer. Int J Mol Sci 24(14):11691. https:\/\/doi.org\/10.3390\/ijms241411691","journal-title":"Int J Mol Sci"},{"key":"5424_CR82","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1093\/ajcp\/61.1.114","volume":"61","author":"LG Morin","year":"1974","unstructured":"Morin LG (1974) Direct colorimetric determination of serum calcium with o-cresolphthalein complexon. Am J Clin Pathol 61:114\u2013117. https:\/\/doi.org\/10.1093\/ajcp\/61.1.114","journal-title":"Am J Clin Pathol"},{"key":"5424_CR83","doi-asserted-by":"publisher","DOI":"10.1016\/j.plefa.2024.102656","volume":"203","author":"Y Mu\u00f1oz","year":"2024","unstructured":"Mu\u00f1oz Y, Mercado L, Farias C, Beyer MP, Alvear I, Echeverr\u00eda F, Valenzuela R (2024) Impact of polyunsaturated fatty acids during and pregnancy and lactation: a comprehensive review. Prostaglandins Leukot Essent Fatty Acids 203:102656. https:\/\/doi.org\/10.1016\/j.plefa.2024.102656","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"5424_CR84","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2023.109497","volume":"124","author":"A Mu\u00f1oz-Jurado","year":"2024","unstructured":"Mu\u00f1oz-Jurado A, Escribano BM, Galv\u00e1n A, Valdelvira ME, Caballero-Villarraso J, Giraldo AI, Santamar\u00eda A, Luque E, Ag\u00fcera E, LaTorre M, T\u00fanez I (2024) Neuroprotective and antioxidant effects of docosahexaenoic acid (DHA) in an experimental model of multiple sclerosis. J Nutr Biochem 124:109497. https:\/\/doi.org\/10.1016\/j.jnutbio.2023.109497","journal-title":"J Nutr Biochem"},{"key":"5424_CR85","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1177\/0960327120975114","volume":"40","author":"R Namoju","year":"2021","unstructured":"Namoju R, Chilaka NK (2021) Alpha-lipoic acid ameliorates cytarabine-induced developmental anomalies in rat fetus. Hum Exp Toxicol 40:851\u2013868. https:\/\/doi.org\/10.1177\/0960327120975114","journal-title":"Hum Exp Toxicol"},{"key":"5424_CR86","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1186\/s43088-022-00240-0","volume":"11","author":"R Namoju","year":"2022","unstructured":"Namoju R, Chilaka NK (2022) Maternal supplementation of \u03b1-lipoic acid attenuates prenatal cytarabine exposure-induced oxidative stress, steroidogenesis suppression and testicular damage in F1 male rat fetus. Beni-Suef Univ J Basic Appl Sci 11:60. https:\/\/doi.org\/10.1186\/s43088-022-00240-0","journal-title":"Beni-Suef Univ J Basic Appl Sci"},{"key":"5424_CR87","doi-asserted-by":"publisher","first-page":"6577","DOI":"10.1007\/s00210-024-03036-4","volume":"397","author":"R Namoju","year":"2024","unstructured":"Namoju R, Chilaka KN (2024) Protective effect of alpha-lipoic acid against in utero cytarabine exposure-induced hepatotoxicity in rat female neonates. Naunyn-Schmiedebergs Arch Pharmacol 397:6577\u20136589. https:\/\/doi.org\/10.1007\/s00210-024-03036-4","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"key":"5424_CR88","doi-asserted-by":"publisher","first-page":"703","DOI":"10.3109\/15376516.2014.970679","volume":"24","author":"RC Namoju","year":"2014","unstructured":"Namoju RC, Khan S, Patel RS, Shera FY, Trivedi PP, Kushwaha S, Jena GB (2014) Pre-pubertal exposure of cytarabine-induced testicular atrophy, impaired spermatogenesis and germ cell DNA damage in SD rats. Toxicol Mech Methods 24:703\u2013712. https:\/\/doi.org\/10.3109\/15376516.2014.970679","journal-title":"Toxicol Mech Methods"},{"key":"5424_CR89","first-page":"109","volume":"168","author":"JE Nash","year":"1989","unstructured":"Nash JE, Persaud TV (1989) Influence of nicotine and caffeine on skeletal development in the rat. Anat Anz 168:109\u2013126","journal-title":"Anat Anz"},{"key":"5424_CR90","doi-asserted-by":"publisher","first-page":"445","DOI":"10.4103\/IJPC.IJPC_82_17","volume":"23","author":"MG Nayak","year":"2017","unstructured":"Nayak MG, George A, Vidyasagar MS, Mathew S, Nayak S, Nayak BS, Shashidhara YN, Kamath A (2017) Quality of life among cancer patients. Indian J Palliat Care 23:445\u2013450. https:\/\/doi.org\/10.4103\/IJPC.IJPC_82_17","journal-title":"Indian J Palliat Care"},{"issue":"19","key":"5424_CR91","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics15192540","volume":"15","author":"G Nemeti","year":"2025","unstructured":"Nemeti G, Jimbu L, Mesaros O, Goidescu IG, Moisa C, Surcel M, Goidescu CM, Boitor-Borza D, Cruciat G, Rotar IC, Muresan D (2025) An account of acute myeloid leukemia complicating pregnancy and literature review. Diagnostics Basel 15(19):2540. https:\/\/doi.org\/10.3390\/diagnostics15192540","journal-title":"Diagnostics Basel"},{"issue":"8","key":"5424_CR92","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1592\/phco.2005.25.8.1134","volume":"25","author":"DM Niedermeier","year":"2005","unstructured":"Niedermeier DM, Frei-Lahr DA, Hall PD (2005) Treatment of acute myeloid leukemia during the second and third trimesters of pregnancy. Pharmacotherapy 25(8):1134\u20131140. https:\/\/doi.org\/10.1592\/phco.2005.25.8.1134","journal-title":"Pharmacotherapy"},{"key":"5424_CR93","doi-asserted-by":"publisher","DOI":"10.1016\/j.jlr.2023.100458","volume":"64","author":"A Oguro","year":"2023","unstructured":"Oguro A, Fujiyama T, Ishihara Y, Kataoka C, Yamamoto M, Eto K, Komohara Y, Imaoka S, Sakuragi T, Tsuji M, Shibata E, Kotake Y, Yamazaki T (2023) Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder. J Lipid Res 64:100458. https:\/\/doi.org\/10.1016\/j.jlr.2023.100458","journal-title":"J Lipid Res"},{"key":"5424_CR94","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","volume":"95","author":"H Ohkawa","year":"1979","unstructured":"Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351\u2013358. https:\/\/doi.org\/10.1016\/0003-2697(79)90738-3","journal-title":"Anal Biochem"},{"key":"5424_CR95","doi-asserted-by":"publisher","unstructured":"Ong KL, Marklund M, Huang L, Rye KA, Hui N, Pan XF, Rebholz CM, Kim H, Steffen LM, van Westing AC, Geleijnse JM, Hoogeveen EK, Chen YY, Chien KL, Fretts AM, Lemaitre RN, Imamura F, Forouhi NG, Wareham NJ, Birukov A, J\u00e4ger S, Kuxhaus O, Schulze MB, de Mello VD, Tuomilehto J, Uusitupa M, Lindstr\u00f6m J, Tintle N, Harris WS, Yamasaki K, Hirakawa Y, Ninomiya T, Tanaka T, Ferrucci L, Bandinelli S, Virtanen JK, Voutilainen A, Jayasena T, Thalamuthu A, Poljak A, Bustamante S, Sachdev PS, Senn MK 2nd, Rich SS, Tsai MY, Wood AC, Laakso M, Lankinen M, Yang X, Sun L, Li H, Lin X, Nowak C, \u00c4rnl\u00f6v J, Ris\u00e9rus U, Lind L, Le Goff M, Samieri C, Helmer C, Qian F, Micha R, Tin A, K\u00f6ttgen A, de Boer IH, Siscovick DS, Mozaffarian D, Wu JH (2023) Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts. BMJ 380:e072909. https:\/\/doi.org\/10.1136\/bmj-2022-072909","DOI":"10.1136\/bmj-2022-072909"},{"issue":"9","key":"5424_CR96","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines8090306","volume":"8","author":"F Oppedisano","year":"2020","unstructured":"Oppedisano F, Macr\u00ec R, Gliozzi M, Musolino V, Carresi C, Maiuolo J, Bosco F, Nucera S, Zito CM, Guarnieri L, Scarano F, Nicita C, Coppoletta AR, Ruga S, Scicchitano M, Mollace R, Palma E, Mollace V (2020) The anti-inflammatory and antioxidant properties of n-3 PUFAs: their role in cardiovascular protection. Biomedicines 8(9):306. https:\/\/doi.org\/10.3390\/biomedicines8090306","journal-title":"Biomedicines"},{"key":"5424_CR97","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1002\/tera.1420440404","volume":"44","author":"A Ortega","year":"1991","unstructured":"Ortega A, Puig M, Domingo JL (1991) Maternal and developmental toxicity of low doses of cytosine arabinoside in mice. Teratology 44:379\u2013384. https:\/\/doi.org\/10.1002\/tera.1420440404","journal-title":"Teratology"},{"key":"5424_CR98","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/5175629","volume":"2017","author":"J Parrott","year":"2017","unstructured":"Parrott J, Holland M (2017) Undetected severe fetal myelosuppression following administration of high-dose cytarabine for acute myeloid leukemia: is more frequent surveillance necessary? Case Rep Obstet Gynecol 2017:5175629. https:\/\/doi.org\/10.1155\/2017\/5175629","journal-title":"Case Rep Obstet Gynecol"},{"key":"5424_CR99","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.tox.2011.12.005","volume":"293","author":"RS Patel","year":"2012","unstructured":"Patel RS, Rachamalla M, Chary NR, Shera FY, Tikoo K, Jena G (2012) Cytarabine induced cerebellar neuronal damage in juvenile rat: correlating neurobehavioral performance with cellular and genetic alterations. Toxicology 293:41\u201352. https:\/\/doi.org\/10.1016\/j.tox.2011.12.005","journal-title":"Toxicology"},{"key":"5424_CR100","doi-asserted-by":"publisher","unstructured":"Patlas N, Golomb G, Yaffe P, Pinto T, Breuer E, Ornoy A (1999) Transplacental effects of bisphosphonates on fetal skeletal ossification and mineralization in rats. Teratology 6:68\u201373. https:\/\/doi.org\/10.1002\/(SICI)1096-9926(199908)60,2<68::AID-TERA10>3.0.CO;2-H","DOI":"10.1002\/(SICI)1096-9926(199908)60,2<68::AID-TERA10>3.0.CO;2-H"},{"key":"5424_CR101","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1016\/j.jnutbio.2012.04.003","volume":"24","author":"AR Patten","year":"2013","unstructured":"Patten AR, Brocardo PS, Christie BR (2013) Omega-3 supplementation can restore glutathione levels and prevent oxidative damage caused by prenatal ethanol exposure. J Nutr Biochem 24:760\u2013769. https:\/\/doi.org\/10.1016\/j.jnutbio.2012.04.003","journal-title":"J Nutr Biochem"},{"key":"5424_CR102","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.ejphar.2017.11.015","volume":"818","author":"EA Pineda-Pe\u00f1a","year":"2018","unstructured":"Pineda-Pe\u00f1a EA, Mart\u00ednez-P\u00e9rez Y, Galicia-Moreno M, Navarrete A, Segovia J, Muriel P, Favari L, Casta\u00f1eda-Hern\u00e1ndez G, Ch\u00e1vez-Pi\u00f1a AE (2018) Participation of the anti-inflammatory and antioxidative activity of docosahexaenoic acid on indomethacin-induced gastric injury model. Eur J Pharmacol 818:585\u2013592. https:\/\/doi.org\/10.1016\/j.ejphar.2017.11.015","journal-title":"Eur J Pharmacol"},{"key":"5424_CR103","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/0890-6238(94)90065-5","volume":"8","author":"ME Rahman","year":"1994","unstructured":"Rahman ME, Ishikawa H, Watanabe Y, Endo A (1994) Carpal and tarsal bone anomalies in mice induced by maternal treatment of Ara-C. Reprod Toxicol 8:41\u201347. https:\/\/doi.org\/10.1016\/0890-6238(94)90065-5","journal-title":"Reprod Toxicol"},{"key":"5424_CR104","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/0890-6238(95)00011-x","volume":"9","author":"ME Rahman","year":"1995","unstructured":"Rahman ME, Ishikawa H, Watanabe Y, Endo A (1995) Stage specificity of Ara-C induced carpal and tarsal bone anomalies in mice. Reprod Toxicol 9:289\u2013296. https:\/\/doi.org\/10.1016\/0890-6238(95)00011-x","journal-title":"Reprod Toxicol"},{"key":"5424_CR105","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/s0890-6238(96)00135-9","volume":"10","author":"ME Rahman","year":"1996","unstructured":"Rahman ME, Ishikawa H, Watanabe Y, Endo A (1996) Carpal and tarsal bone development is highly sensitive to three antiproliferative teratogens in mice. Reprod Toxicol 10:485\u2013489. https:\/\/doi.org\/10.1016\/s0890-6238(96)00135-9","journal-title":"Reprod Toxicol"},{"key":"5424_CR106","doi-asserted-by":"publisher","first-page":"S108","DOI":"10.1177\/15648265100312S203","volume":"31","author":"U Ramakrishnan","year":"2010","unstructured":"Ramakrishnan U, Stein AD, Parra-Cabrera S, Wang M, Imhoff-Kunsch B, Ju\u00e1rez-M\u00e1rquez S, Rivera J, Martorell R (2010) Effects of docosahexaenoic acid supplementation during pregnancy on gestational age and size at birth: randomized, double-blind, placebo-controlled trial in Mexico. Food Nutr Bull 31:S108\u2013S116. https:\/\/doi.org\/10.1177\/15648265100312S203","journal-title":"Food Nutr Bull"},{"issue":"7","key":"5424_CR107","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1200\/JCO.1987.5.7.1098","volume":"5","author":"EE Reynoso","year":"1987","unstructured":"Reynoso EE, Shepherd FA, Messner HA, Farquharson HA, Garvey MB, Baker MA (1987) Acute leukemia during pregnancy: the Toronto Leukemia Study Group experience with long-term follow-up of children exposed in utero to chemotherapeutic agents. J Clin Oncol 5(7):1098\u20131106. https:\/\/doi.org\/10.1200\/JCO.1987.5.7.1098","journal-title":"J Clin Oncol"},{"key":"5424_CR108","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1002\/tera.1420040103","volume":"4","author":"EJ Ritter","year":"1971","unstructured":"Ritter EJ, Scott WJ, Wilson JG (1971) Teratogenesis and inhibition of DNA synthesis induced in rat embryos by cytosine arabinoside. Teratology 4:7\u201313. https:\/\/doi.org\/10.1002\/tera.1420040103","journal-title":"Teratology"},{"key":"5424_CR109","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1002\/tera.1420070302","volume":"7","author":"EJ Ritter","year":"1973","unstructured":"Ritter EJ, Scott WJ, Wilson JG (1973) Relationship of temporal patterns of cell death and development to malformations in the rat limb, possible mechanisms of teratogenesis with inhibitors of DNA synthesis. Teratology 7:219\u2013225. https:\/\/doi.org\/10.1002\/tera.1420070302","journal-title":"Teratology"},{"key":"5424_CR110","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1126\/science.179.4073.588","volume":"179","author":"JT Rotruck","year":"1973","unstructured":"Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra WG (1973) Selenium: biochemical role as a component of glutathione peroxidase. Science 179:588\u2013590. https:\/\/doi.org\/10.1126\/science.179.4073.588","journal-title":"Science"},{"key":"5424_CR111","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1590\/S151689132012000200009","volume":"55","author":"MVC Rudge","year":"2012","unstructured":"Rudge MVC, Costa E, Barbisan LF, Damasceno DC, Bueno A, Saito FH, Calderon IMP, Rodrigues MMP (2012) Evaluation of cell proliferation and apoptosis in placentas of rats with severe diabetes. Braz Arch Biol Technol 55:243\u2013250. https:\/\/doi.org\/10.1590\/S151689132012000200009","journal-title":"Braz Arch Biol Technol"},{"key":"5424_CR112","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/0163-7258(92)90022-r","volume":"56","author":"YM Rustum","year":"1992","unstructured":"Rustum YM, Raymakers RA (1992) 1-Beta-arabinofuranosylcytosine in therapy of leukemia: preclinical and clinical overview. Pharmacol Ther 56:307\u2013321. https:\/\/doi.org\/10.1016\/0163-7258(92)90022-r","journal-title":"Pharmacol Ther"},{"key":"5424_CR113","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187934","volume":"12","author":"C Sakai","year":"2017","unstructured":"Sakai C, Ishida M, Ohba H, Yamashita H, Uchida H, Yoshizumi M, Ishida T (2017) Fish oil omega-3 polyunsaturated fatty acids attenuate oxidative stress-induced DNA damage in vascular endothelial cells. PLoS One 12:e0187934. https:\/\/doi.org\/10.1371\/journal.pone.0187934","journal-title":"PLoS One"},{"key":"5424_CR114","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.envint.2017.11.001","volume":"111","author":"M Sakamoto","year":"2018","unstructured":"Sakamoto M, Chan HM, Domingo JL, Koriyama C, Murata K (2018) Placental transfer and levels of mercury, selenium, vitamin E, and docosahexaenoic acid in maternal and umbilical cord blood. Environ Int 111:309\u2013315. https:\/\/doi.org\/10.1016\/j.envint.2017.11.001","journal-title":"Environ Int"},{"key":"5424_CR115","doi-asserted-by":"publisher","first-page":"4275","DOI":"10.1007\/s00210-023-02881-z","volume":"397","author":"MI S\u00e1nchez-Trigueros","year":"2024","unstructured":"S\u00e1nchez-Trigueros MI, Mart\u00ednez-Vieyra IA, Pineda-Pe\u00f1a EA, Casta\u00f1eda-Hern\u00e1ndez G, Perez-Cruz C, Cerecedo D, Ch\u00e1vez-Pi\u00f1a AE (2024) Role of antioxidative activity in the docosahexaenoic acid\u2019s enteroprotective effect in the indomethacin-induced small intestinal injury model. Naunyn Schmiedebergs Arch Pharmacol 397:4275\u20134285. https:\/\/doi.org\/10.1007\/s00210-023-02881-z","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"5424_CR116","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1016\/j.bpobgyn.2009.05.003","volume":"23","author":"S Sankaran","year":"2009","unstructured":"Sankaran S, Kyle PM (2009) Aetiology and pathogenesis of IUGR. Best Pract Res Clin Obstet Gynaecol 23:765\u2013777. https:\/\/doi.org\/10.1016\/j.bpobgyn.2009.05.003","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"5424_CR117","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.placenta.2018.03.003","volume":"69","author":"MH Schoots","year":"2018","unstructured":"Schoots MH, Gordijn SJ, Scherjon SA, van Goor H, Hillebrands JL (2018) Oxidative stress in placental pathology. Placenta 69:153\u2013161. https:\/\/doi.org\/10.1016\/j.placenta.2018.03.003","journal-title":"Placenta"},{"key":"5424_CR118","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/0012-1606(75)90245-6","volume":"45","author":"WJ Scott","year":"1975","unstructured":"Scott WJ, Ritter EJ, Wilson JG (1975) Studies on induction of polydactyly in rats with cytosine arabinoside. Dev Biol 45:103\u2013111. https:\/\/doi.org\/10.1016\/0012-1606(75)90245-6","journal-title":"Dev Biol"},{"key":"5424_CR119","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V130.Suppl_1.5035.5035","volume":"130","author":"MB Seegars","year":"2017","unstructured":"Seegars MB, Powell BL, Howard DS (2017) Acute myeloid leukemia in pregnancy. Blood 130:5035. https:\/\/doi.org\/10.1182\/blood.V130.Suppl_1.5035.5035","journal-title":"Blood"},{"key":"5424_CR120","doi-asserted-by":"publisher","DOI":"10.3390\/nu16050687","volume":"16","author":"B Shahabi","year":"2024","unstructured":"Shahabi B, Hern\u00e1ndez-Mart\u00ednez C, Voltas N, Canals J, Arija V (2024) The maternal omega-3 long-chain polyunsaturated fatty acid concentration in early pregnancy and infant neurodevelopment: the ECLIPSES study. Nutrients 16:687. https:\/\/doi.org\/10.3390\/nu16050687","journal-title":"Nutrients"},{"key":"5424_CR121","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1111\/1440-1681.13757","volume":"50","author":"L Shang","year":"2023","unstructured":"Shang L, Ma H, Zhang X, Mao R, Ma C, Ruan Z (2023) Docosahexaenoic acid alleviates the excessive degradation of extracellular matrix in the nucleus pulposus by reducing the content of lncRNA NEAT1 to prevent the progression of intervertebral disc degeneration. Clin Exp Pharmacol Physiol 50:403\u2013414. https:\/\/doi.org\/10.1111\/1440-1681.13757","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"5424_CR122","doi-asserted-by":"publisher","first-page":"6103","DOI":"10.1039\/d1fo04178a","volume":"13","author":"HH Shi","year":"2022","unstructured":"Shi HH, Chen LP, Wang CC, Zhao YC, Wang YM, Xue CH, Zhang TT (2022) Docosahexaenoic acid-acylated curcumin diester alleviates cisplatin-induced acute kidney injury by regulating the effect of gut microbiota on the lipopolysaccharide- and trimethylamine-N-oxide-mediated PI3K\/Akt\/NF-\u03baB signaling pathway in mice. Food Funct 13:6103\u20136117. https:\/\/doi.org\/10.1039\/d1fo04178a","journal-title":"Food Funct"},{"key":"5424_CR123","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2022.108972","volume":"104","author":"P Shi","year":"2022","unstructured":"Shi P, Song C, Qi H et al (2022) Up-regulation of IRF3 is required for docosahexaenoic acid suppressing ferroptosis of cardiac microvascular endothelial cells in cardiac hypertrophy rat. J Nutr Biochem 104:108972. https:\/\/doi.org\/10.1016\/j.jnutbio.2022.108972","journal-title":"J Nutr Biochem"},{"key":"5424_CR124","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/568671","volume":"2013","author":"S Shin","year":"2013","unstructured":"Shin S, Jing K, Jeong S, Kim N, Song KS, Heo JY, Park JH, Seo KS, Han J, Park JI, Kweon GR, Park SK, Wu T, Hwang BD, Lim K (2013) The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53. BioMed Res Int 2013:568671. https:\/\/doi.org\/10.1155\/2013\/568671","journal-title":"BioMed Res Int"},{"key":"5424_CR125","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1590\/s0102-865020180090000009","volume":"33","author":"P Shi","year":"2018","unstructured":"Silveira AS, Aydos RD, Ramalho RT, Silva IS, Caldas RA, Santos Neto ATD, Rodrigues CT\u00a0(2018) Oxidative stress effects in the uterus, placenta and fetus of pregnant rats submitted to acute and chronic stress. Acta Cir Bras 33:806\u2013815. https:\/\/doi.org\/10.1590\/s0102-865020180090000009","journal-title":"Acta Cir Bras"},{"key":"5424_CR126","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/j.bone.2004.11.011","volume":"36","author":"ME Simpson","year":"2005","unstructured":"Simpson ME, Duggal S, Keiver K (2005) Prenatal ethanol exposure has differential effects on fetal growth and skeletal ossification. Bone 36:521\u2013532. https:\/\/doi.org\/10.1016\/j.bone.2004.11.011","journal-title":"Bone"},{"key":"5424_CR127","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/00032697(72)90132-7","volume":"47","author":"AK Sinha","year":"1972","unstructured":"Sinha AK (1972) Colorimetric assay of catalase. Anal Biochem 47:389\u2013394. https:\/\/doi.org\/10.1016\/00032697(72)90132-7","journal-title":"Anal Biochem"},{"key":"5424_CR128","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1002\/biof.1556","volume":"45","author":"SA Soto-Alarc\u00f3n","year":"2019","unstructured":"Soto-Alarc\u00f3n SA, Ortiz M, Orellana P, Echeverr\u00eda F, Bustamante A, Espinosa A, Illesca P, Gonzalez-Ma\u00f1\u00e1n D, Valenzuela R, Videla LA (2019) Docosahexaenoic acid and hydroxytyrosol co-administration fully prevents liver steatosis and related parameters in mice subjected to high-fat diet: a molecular approach. Biofactors 45:930\u2013943. https:\/\/doi.org\/10.1002\/biof.1556","journal-title":"Biofactors"},{"key":"5424_CR129","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1530\/REP-13-0239","volume":"146","author":"MJ Stark","year":"2013","unstructured":"Stark MJ, Clifton VL, Hodyl NA (2013) Differential effects of docosahexaenoic acid on preterm and term placental pro-oxidant\/antioxidant balance. Reproduction 146:243\u2013251. https:\/\/doi.org\/10.1530\/REP-13-0239","journal-title":"Reproduction"},{"key":"5424_CR130","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19123729","volume":"19","author":"JG Steller","year":"2018","unstructured":"Steller JG, Alberts JR, Ronca AE (2018) Oxidative stress as cause, consequence, or biomarker of altered female reproduction and development in the space environment. Int J Mol Sci 19:3729. https:\/\/doi.org\/10.3390\/ijms19123729","journal-title":"Int J Mol Sci"},{"key":"5424_CR131","doi-asserted-by":"publisher","first-page":"7","DOI":"10.2165\/00002018-199005010-00003","volume":"5","author":"J Stentoft","year":"1990","unstructured":"Stentoft J (1990) The toxicity of cytarabine. Drug Saf 5:7\u201327. https:\/\/doi.org\/10.2165\/00002018-199005010-00003","journal-title":"Drug Saf"},{"key":"5424_CR132","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.116153","volume":"171","author":"Y Su","year":"2024","unstructured":"Su Y, Han Y, Choi HS, Lee GY, Cho HW, Choi H, Choi JH, Jang YS, Seo JW (2024) Lipid mediators obtained from docosahexaenoic acid by soybean lipoxygenase attenuate RANKL-induced osteoclast differentiation and rheumatoid arthritis. Biomed Pharmacother 171:116153. https:\/\/doi.org\/10.1016\/j.biopha.2024.116153","journal-title":"Biomed Pharmacother"},{"key":"5424_CR133","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0266084","volume":"17","author":"J Sun","year":"2022","unstructured":"Sun J, Zhang W (2022) Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats. PLoS One 17:e0266084. https:\/\/doi.org\/10.1371\/journal.pone.0266084","journal-title":"PLoS One"},{"key":"5424_CR134","first-page":"5","volume":"24","author":"Y Takehira","year":"1979","unstructured":"Takehira Y, Shimamura K, Ishizaka K, Kameyama Y (1979) Species differences of cytosine arabinoside induced poly- and oligodactylism in rat and mouse. Annu Rep Res Inst Environ Med Nagoya Univ 24:5\u201312","journal-title":"Annu Rep Res Inst Environ Med Nagoya Univ"},{"key":"5424_CR135","unstructured":"Tal R, Taylor HS (2021) Endocrinology of Pregnancy. In: Feingold KR, Anawalt B, Blackman MR et al (eds) Endotext. South Dartmouth (MA): MDText.com. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK278962\/. Accessed 18 Mar 2025"},{"key":"5424_CR136","doi-asserted-by":"publisher","unstructured":"T\u00fcrkez H, Geyikoglu F, Yousef\u00a0MI (2012) Ameliorative effect of docosahexaenoic acid on 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced histological changes, oxidative stress, and DNA damage in rat liver.\u00a0Toxicol Ind Health 28(8):687\u2013696. https:\/\/doi.org\/10.1177\/0748233711420475","DOI":"10.1177\/0748233711420475"},{"issue":"3","key":"5424_CR137","doi-asserted-by":"publisher","first-page":"616","DOI":"10.3109\/10428194.2015.1065977","volume":"57","author":"V Verma","year":"2016","unstructured":"Verma V, Giri S, Manandhar S, Pathak R, Bhatt VR (2016) Acute promyelocytic leukemia during pregnancy: a systematic analysis of outcome. Leuk Lymphoma 57(3):616\u2013622. https:\/\/doi.org\/10.3109\/10428194.2015.1065977","journal-title":"Leuk Lymphoma"},{"key":"5424_CR138","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1242\/dev.120.5.1109","volume":"120","author":"J Wallin","year":"1994","unstructured":"Wallin J, Wilting J, Koseki H, Fritsch R, Christ B, Balling R (1994) The role of Pax-1 in axial skeleton development. Development 120:1109\u20131121. https:\/\/doi.org\/10.1242\/dev.120.5.1109","journal-title":"Development"},{"key":"5424_CR139","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.803994","volume":"11","author":"P Wang","year":"2021","unstructured":"Wang P, Yang Z, Shan M, Lu S, Zhang L, Li S, Hu S, Tian H, Xu Y, Wu D (2021) Maternal and fetal outcomes of acute leukemia in pregnancy: a retrospective study of 52 patients. Front Oncol 11:803994. https:\/\/doi.org\/10.3389\/fonc.2021.803994","journal-title":"Front Oncol"},{"key":"5424_CR140","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1016\/j.jnutbio.2005.05.012","volume":"17","author":"BA Watkins","year":"2006","unstructured":"Watkins BA, Li Y, Seifert MF (2006) Dietary ratio of n-6\/n-3 PUFAs and docosahexaenoic acid: actions on bone mineral and serum biomarkers in ovariectomized rats. J Nutr Biochem 17:282\u2013289. https:\/\/doi.org\/10.1016\/j.jnutbio.2005.05.012","journal-title":"J Nutr Biochem"},{"key":"5424_CR141","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1136\/ijgc-2020-001776","volume":"31","author":"V Wolters","year":"2021","unstructured":"Wolters V, Heimovaara J, Maggen C, Cardonick E, Boere I, Lenaerts L, Amant F (2021) Management of pregnancy in women with cancer. Int J Gynecol Cancer 31:314\u2013322. https:\/\/doi.org\/10.1136\/ijgc-2020-001776","journal-title":"Int J Gynecol Cancer"},{"key":"5424_CR142","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2018.00570","volume":"9","author":"L Woods","year":"2018","unstructured":"Woods L, Perez-Garcia V, Hemberger M (2018) Regulation of placental development and its impact on fetal growth-new insights from mouse models. Front Endocrinol 9:570. https:\/\/doi.org\/10.3389\/fendo.2018.00570","journal-title":"Front Endocrinol"},{"key":"5424_CR143","unstructured":"World Health Organization (2024) Global cancer burden growing amidst mounting need for services. WHO. https:\/\/www.who.int\/news\/item\/01-02-2024-global-cancer-burden-growing--amidst-mounting-need-for-services. Accessed on: 18MAR2025."},{"key":"5424_CR144","doi-asserted-by":"publisher","unstructured":"Yadav D, Ostrea EM Jr, Cheng CT, Kisseih E, Maddipati KR, Thomas RL (2024) Effect of docosahexaenoic acid and olive oil supplementation on pup weight in alcohol-exposed pregnant rats. Front Pediatr 12:1334285. https:\/\/doi.org\/10.3389\/fped.2024.1334285","DOI":"10.3389\/fped.2024.1334285"},{"key":"5424_CR145","doi-asserted-by":"publisher","first-page":"1762","DOI":"10.1095\/biolreprod.103.026252","volume":"70","author":"H Yamauchi","year":"2004","unstructured":"Yamauchi H, Katayama K, Ueno M et al (2004a) Involvement of p53 in 1-beta-D-arabinofuranosylcytosine-induced trophoblastic cell apoptosis and impaired proliferation in rat placenta. Biol Reprod 70:1762\u20131767. https:\/\/doi.org\/10.1095\/biolreprod.103.026252","journal-title":"Biol Reprod"},{"key":"5424_CR146","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1016\/j.ntt.2004.03.010","volume":"26","author":"H Yamauchi","year":"2004","unstructured":"Yamauchi H, Katayama K-I, Ueno M et al (2004b) Involvement of p53 in 1-beta-D-arabinofuranosylcytosine-induced rat fetal brain lesions. Neurotoxicol Teratol 26:579\u2013586. https:\/\/doi.org\/10.1016\/j.ntt.2004.03.010","journal-title":"Neurotoxicol Teratol"},{"issue":"3","key":"5424_CR147","doi-asserted-by":"publisher","first-page":"228","DOI":"10.11406\/rinketsu.61.228","volume":"61","author":"Y Yanai","year":"2020","unstructured":"Yanai Y, Takano K, Nagamatsu K, Sakata M, Katayama O, Yoshida N, Honda S, Kawano R, Ogata M, Morita T, Nishida Y, Narahara H, Shirao K (2020) [Rinsho ketsueki]. Jpn J Clin Hematol 61(3):228\u2013233. https:\/\/doi.org\/10.11406\/rinketsu.61.228","journal-title":"Jpn J Clin Hematol"},{"issue":"1","key":"5424_CR148","doi-asserted-by":"publisher","first-page":"126","DOI":"10.12892\/ejgo200401126","volume":"25","author":"MS Yucebilgin","year":"2004","unstructured":"Yucebilgin MS, Cagirgan S, Donmez A, Ozkinay E, Akercan F, Mgoyi L, Vural F (2004) Acute myeloblastic leukemia in pregnancy: a case report and review of the literature. Eur J Gynaecol Oncol 25(1):126\u2013128. https:\/\/doi.org\/10.12892\/ejgo200401126","journal-title":"Eur J Gynaecol Oncol"},{"issue":"12","key":"5424_CR149","doi-asserted-by":"publisher","DOI":"10.3390\/nu13124243","volume":"13","author":"E Zambrano","year":"2021","unstructured":"Zambrano E, Rodr\u00edguez-Gonz\u00e1lez GL, Reyes-Castro LA, Bautista CJ, Castro-Rodr\u00edguez DC, Ju\u00e1rez-Pilares G, Ib\u00e1\u00f1ez CA, Hern\u00e1ndez-Rojas A, Nathanielsz PW, Monta\u00f1o S, Arredondo A, Huang F, Bola\u00f1os-Jim\u00e9nez F (2021) DHA supplementation of obese rats throughout pregnancy and lactation modifies milk composition and anxiety behavior of offspring. Nutrients 13(12):4243. https:\/\/doi.org\/10.3390\/nu13124243","journal-title":"Nutrients"},{"issue":"1","key":"5424_CR150","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1080\/07853890.2021.1908586","volume":"53","author":"D Zhu","year":"2021","unstructured":"Zhu D, Tang D, Chai X, Zhang G, Wang Y (2021) Acute leukemia in pregnancy: a single institutional experience with 21 cases at 10 years and a review of the literature. Ann Med 53(1):567\u2013575. https:\/\/doi.org\/10.1080\/07853890.2021.1908586","journal-title":"Ann Med"}],"container-title":["Naunyn-Schmiedeberg's Archives of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-026-05424-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00210-026-05424-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00210-026-05424-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T03:03:08Z","timestamp":1784775788000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00210-026-05424-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,12]]},"references-count":150,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["5424"],"URL":"https:\/\/doi.org\/10.1007\/s00210-026-05424-4","relation":{},"ISSN":["0028-1298","1432-1912"],"issn-type":[{"value":"0028-1298","type":"print"},{"value":"1432-1912","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,12]]},"assertion":[{"value":"21 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Ethical approval Institutional Animal Ethics Committee (IAEC) has approved the protocol (Approval Number: IAEC\/GIP-1287\/ASN-S\/Approved\/9\/Dec2023).","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}