{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T03:06:20Z","timestamp":1785294380631,"version":"3.55.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2006,11,10]],"date-time":"2006-11-10T00:00:00Z","timestamp":1163116800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychopharmacology"],"published-print":{"date-parts":[[2007,2,15]]},"DOI":"10.1007\/s00213-006-0613-y","type":"journal-article","created":{"date-parts":[[2006,11,9]],"date-time":"2006-11-09T12:55:46Z","timestamp":1163076946000},"page":"119-125","source":"Crossref","is-referenced-by-count":40,"title":["Hyperalgesia, low-anxiety, and impairment of avoidance learning in neonatal caffeine-treated rats"],"prefix":"10.1007","volume":"191","author":[{"given":"Hong-Zhen","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hwei-Hsien","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,11,10]]},"reference":[{"key":"613_CR1","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1203\/00006450-200008000-00010","volume":"48","author":"U Aden","year":"2000","unstructured":"Aden U, Herlenius E, Tang LQ, Fredholm BB (2000) Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain. Pediatr Res 48:177\u2013183","journal-title":"Pediatr Res"},{"key":"613_CR2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1177\/026988119701100304","volume":"11","author":"SK Bhattacharya","year":"1997","unstructured":"Bhattacharya SK, Satyan KS, Chakrabarti A (1997) Anxiogenic action of caffeine: an experimental study in rats. J Psychopharmacol 11:219\u2013224","journal-title":"J Psychopharmacol"},{"key":"613_CR3","doi-asserted-by":"crossref","first-page":"61","DOI":"10.2165\/00128072-200103010-00005","volume":"3","author":"AM Comer","year":"2001","unstructured":"Comer AM, Perry CM, Figgitt DP (2001) Caffeine citrate: a review of its use in apnoea of prematurity. Paediatr Drugs 3:61\u201379","journal-title":"Paediatr Drugs"},{"key":"613_CR4","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s002130050037","volume":"148","author":"M Yacoubi El","year":"2000","unstructured":"El Yacoubi M, Ledent C, Parmentier M, Costentin J, Vaugeois JM (2000) The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists. Psychopharmacology 148:153\u2013163","journal-title":"Psychopharmacology"},{"key":"613_CR5","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0165-3806(94)90165-1","volume":"82","author":"BA Etzel","year":"1994","unstructured":"Etzel BA, Guillet R (1994) Effects of neonatal exposure to caffeine on adenosine A1 receptor ontogeny using autoradiography. Brain Res Dev Brain Res 82:223\u2013230","journal-title":"Brain Res Dev Brain Res"},{"key":"613_CR6","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0165-3806(96)00158-7","volume":"98","author":"S Fisher","year":"1997","unstructured":"Fisher S, Guillet R (1997) Neonatal caffeine alters passive avoidance retention in rats in an age- and gender-related manner. Brain Res Dev Brain Res 98:145\u2013149","journal-title":"Brain Res Dev Brain Res"},{"key":"613_CR7","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1891\/0730-0832.19.8.33","volume":"19","author":"BA Gannon","year":"2000","unstructured":"Gannon BA (2000) Theophylline or caffeine: which is best for apnea of prematurity? Neonatal Netw 19:33\u201336","journal-title":"Neonatal Netw"},{"key":"613_CR8","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1007\/PL00005094","volume":"356","author":"C Ghelardini","year":"1997","unstructured":"Ghelardini C, Galeotti N, Bartolini A (1997) Caffeine induces central cholinergic analgesia. Naunyn Schmiedebergs Arch Pharmacol 356:590\u2013595","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"613_CR9","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1046\/j.1460-9568.2002.02122.x","volume":"16","author":"L Gimenez-Llort","year":"2002","unstructured":"Gimenez-Llort L, Fernandez-Teruel A, Escorihuela RM, Fredholm BB, Tobena A, Pekny M, Johansson B (2002) Mice lacking the adenosine A1 receptor are anxious and aggressive, but are normal learners with reduced muscle strength and survival rate. Eur J Neurosci 16:547\u2013550","journal-title":"Eur J Neurosci"},{"key":"613_CR10","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1159\/000457627","volume":"15","author":"R Guillet","year":"1990","unstructured":"Guillet R (1990) Neonatal caffeine exposure alters adenosine receptor control of locomotor activity in the developing rat. Dev Pharmacol Ther 15:94\u2013100","journal-title":"Dev Pharmacol Ther"},{"key":"613_CR11","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/j.1528-1157.1995.tb01610.x","volume":"36","author":"R Guillet","year":"1995","unstructured":"Guillet R, Dunham L (1995) Neonatal caffeine exposure and seizure susceptibility in adult rats. Epilepsia 36:743\u2013749","journal-title":"Epilepsia"},{"key":"613_CR12","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/0028-3908(91)90011-Y","volume":"30","author":"R Guillet","year":"1991","unstructured":"Guillet R, Kellogg C (1991a) Neonatal exposure to therapeutic caffeine alters the ontogeny of adenosine A1 receptors in brain of rats. Neuropharmacology 30:489\u2013496","journal-title":"Neuropharmacology"},{"key":"613_CR13","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/0091-3057(91)90091-F","volume":"40","author":"R Guillet","year":"1991","unstructured":"Guillet R, Kellogg CK (1991b) Neonatal caffeine exposure alters developmental sensitivity to adenosine receptor ligands. Pharmacol Biochem Behav 40:811\u2013817","journal-title":"Pharmacol Biochem Behav"},{"key":"613_CR14","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0166-4328(00)00307-7","volume":"118","author":"W Hauber","year":"2001","unstructured":"Hauber W, Bareiss A (2001) Facilitative effects of an adenosine A1\/A2 receptor blockade on spatial memory performance of rats: selective enhancement of reference memory retention during the light period. Behav Brain Res 118:43\u201352","journal-title":"Behav Brain Res"},{"key":"613_CR15","doi-asserted-by":"crossref","first-page":"9407","DOI":"10.1073\/pnas.161292398","volume":"98","author":"B Johansson","year":"2001","unstructured":"Johansson B, Halldner L, Dunwiddie TV, Masino SA, Poelchen W, Gimenez-Llort L, Escorihuela RM, Fernandez-Teruel A, Wiesenfeld-Hallin Z, Xu XJ, Hardemark A, Betsholtz C, Herlenius E, Fredholm BB (2001) Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor. Proc Natl Acad Sci USA 98:9407\u20139412","journal-title":"Proc Natl Acad Sci USA"},{"key":"613_CR16","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/S0028-3908(99)00187-2","volume":"39","author":"RT Khisti","year":"2000","unstructured":"Khisti RT, Chopde CT, Abraham E (2000) GABAergic involvement in motor effects of an adenosine A(2A) receptor agonist in mice. Neuropharmacology 39:1004\u20131015","journal-title":"Neuropharmacology"},{"key":"613_CR17","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1038\/41771","volume":"388","author":"C Ledent","year":"1997","unstructured":"Ledent C, Vaugeois JM, Schiffmann SN, Pedrazzini T, El Yacoubi M, Vanderhaeghen JJ, Costentin J, Heath JK, Vassart G, Parmentier M (1997) Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor. Nature 388:674\u2013678","journal-title":"Nature"},{"key":"613_CR18","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1046\/j.1471-4159.2002.01008.x","volume":"82","author":"D Leon","year":"2002","unstructured":"Leon D, Albasanz JL, Ruiz MA, Fernandez M, Martin M (2002) Adenosine A1 receptor down-regulation in mothers and fetal brain after caffeine and theophylline treatments to pregnant rats. J Neurochem 82:625\u2013634","journal-title":"J Neurochem"},{"key":"613_CR19","doi-asserted-by":"crossref","first-page":"3013","DOI":"10.1097\/00001756-199611250-00043","volume":"7","author":"M Ohno","year":"1996","unstructured":"Ohno M, Watanabe S (1996) Working memory failure by stimulation of hippocampal adenosine A1 receptors in rats. Neuroreport 7:3013\u20133016","journal-title":"Neuroreport"},{"key":"613_CR20","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.nlm.2004.12.002","volume":"83","author":"GS Pereira","year":"2005","unstructured":"Pereira GS, Rossato JI, Sarkis JJ, Cammarota M, Bonan CD, Izquierdo I (2005) Activation of adenosine receptors in the posterior cingulate cortex impairs memory retrieval in the rat. Neurobiol Learn Mem 83:217\u2013223","journal-title":"Neurobiol Learn Mem"},{"key":"613_CR21","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0304-3959(94)00169-F","volume":"61","author":"J Sawynok","year":"1995","unstructured":"Sawynok J, Reid AR, Doak GJ (1995) Caffeine antinociception in the rat hot-plate and formalin tests and locomotor stimulation: involvement of noradrenergic mechanisms. Pain 61:203\u2013213","journal-title":"Pain"},{"key":"613_CR22","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1159\/000087584","volume":"88","author":"B Schmidt","year":"2005","unstructured":"Schmidt B (2005) Methylxanthine therapy for apnea of prematurity: evaluation of treatment benefits and risks at age 5\u00a0years in the international Caffeine for Apnea of Prematurity (CAP) trial. Biol Neonate 88:208\u2013213","journal-title":"Biol Neonate"},{"key":"613_CR23","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0091-3057(91)90317-U","volume":"40","author":"SR Ticho","year":"1991","unstructured":"Ticho SR, Radulovacki M (1991) Role of adenosine in sleep and temperature regulation in the preoptic area of rats. Pharmacol Biochem Behav 40:33\u201340","journal-title":"Pharmacol Biochem Behav"},{"key":"613_CR24","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.expneurol.2006.01.005","volume":"199","author":"JH Wang","year":"2006","unstructured":"Wang JH, Ma YY, van den Buuse M (2006) Improved spatial recognition memory in mice lacking adenosine A(2A) receptors. Exp Neurol 199:438\u2013445","journal-title":"Exp Neurol"}],"container-title":["Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00213-006-0613-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00213-006-0613-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00213-006-0613-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T12:31:31Z","timestamp":1558614691000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00213-006-0613-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11,10]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,2,15]]}},"alternative-id":["613"],"URL":"https:\/\/doi.org\/10.1007\/s00213-006-0613-y","relation":{},"ISSN":["0033-3158","1432-2072"],"issn-type":[{"value":"0033-3158","type":"print"},{"value":"1432-2072","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,11,10]]}}}