{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T13:09:44Z","timestamp":1776258584360,"version":"3.50.1"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T00:00:00Z","timestamp":1543536000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T00:00:00Z","timestamp":1543536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R01DA025674"],"award-info":[{"award-number":["R01DA025674"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Psychopharmacology"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1007\/s00213-018-5132-0","type":"journal-article","created":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T01:27:11Z","timestamp":1543541231000},"page":"1261-1272","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Increased cocaine reward in offspring of females exposed to morphine during adolescence"],"prefix":"10.1007","volume":"236","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5317-7174","authenticated-orcid":false,"given":"Fair M.","family":"Vassoler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anika M.","family":"Toorie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth M.","family":"Byrnes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,11,30]]},"reference":[{"key":"5132_CR1","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1038\/nrn3104","volume":"12","author":"A Badiani","year":"2011","unstructured":"Badiani A, Belin D, Epstein D, Calu D, Shaham Y (2011) Opiate versus psychostimulant addiction: the differences do matter. Nat Rev Neurosci 12:685\u2013700","journal-title":"Nat Rev Neurosci"},{"key":"5132_CR2","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1007\/s00210-002-0533-2","volume":"365","author":"A Becker","year":"2002","unstructured":"Becker A, Grecksch G, Kraus J, Loh HH, Schroeder H, Hollt V (2002) Rewarding effects of ethanol and cocaine in mu opioid receptor-deficient mice. Naunyn Schmiedeberg's Arch Pharmacol 365:296\u2013302","journal-title":"Naunyn Schmiedeberg's Arch Pharmacol"},{"key":"5132_CR3","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1007\/s00213-005-0122-4","volume":"182","author":"EM Byrnes","year":"2005","unstructured":"Byrnes EM (2005) Transgenerational consequences of adolescent morphine exposure in female rats: effects on anxiety-like behaviors and morphine sensitization in adult offspring. Psychopharmacology 182:537\u2013544","journal-title":"Psychopharmacology"},{"key":"5132_CR4","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.bbr.2010.11.059","volume":"218","author":"JJ Byrnes","year":"2011","unstructured":"Byrnes JJ, Babb JA, Scanlan VF, Byrnes EM (2011) Adolescent opioid exposure in female rats: transgenerational effects on morphine analgesia and anxiety-like behavior in adult offspring. Behav Brain Res 218:200\u2013205","journal-title":"Behav Brain Res"},{"key":"5132_CR5","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1007\/s00213-012-2960-1","volume":"227","author":"JJ Byrnes","year":"2013","unstructured":"Byrnes JJ, Johnson NL, Carini LM, Byrnes EM (2013) Multigenerational effects of adolescent morphine exposure on dopamine D2 receptor function. Psychopharmacology 227:263\u2013272","journal-title":"Psychopharmacology"},{"key":"5132_CR6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0022-3565(25)24984-9","volume":"238","author":"ME Carroll","year":"1986","unstructured":"Carroll ME, Lac ST, Walker MJ, Kragh R, Newman T (1986) Effects of naltrexone on intravenous cocaine self-administration in rats during food satiation and deprivation. J Pharmacol Exp Ther 238:1\u20137","journal-title":"J Pharmacol Exp Ther"},{"key":"5132_CR7","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.semcdb.2015.07.003","volume":"43","author":"HJ Clarke","year":"2015","unstructured":"Clarke HJ, Vieux KF (2015) Epigenetic inheritance through the female germ-line: the known, the unknown, and the possible. Semin Cell Dev Biol 43:106\u2013116","journal-title":"Semin Cell Dev Biol"},{"key":"5132_CR8","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/S0022-3565(24)36712-6","volume":"281","author":"V Deroche","year":"1997","unstructured":"Deroche V, Marinelli M, Le Moal M, Piazza PV (1997) Glucocorticoids and behavioral effects of psychostimulants. II: cocaine intravenous self-administration and reinstatement depend on glucocorticoid levels. J Pharmacol Exp Ther 281:1401\u20131407","journal-title":"J Pharmacol Exp Ther"},{"key":"5132_CR9","doi-asserted-by":"publisher","first-page":"2508","DOI":"10.1038\/npp.2013.155","volume":"38","author":"Y Dikshtein","year":"2013","unstructured":"Dikshtein Y, Barnea R, Kronfeld N, Lax E, Roth-Deri I, Friedman A, Gispan I, Elharrar E, Levy S, Ben-Tzion M, Yadid G (2013) Beta-endorphin via the delta opioid receptor is a major factor in the incubation of cocaine craving. Neuropsychopharmacology 38:2508\u20132514","journal-title":"Neuropsychopharmacology"},{"key":"5132_CR10","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.psyneuen.2008.09.014","volume":"34","author":"MW Feltenstein","year":"2009","unstructured":"Feltenstein MW, Byrd EA, Henderson AR, See RE (2009) Attenuation of cocaine-seeking by progesterone treatment in female rats. Psychoneuroendocrinology 34:343\u2013352","journal-title":"Psychoneuroendocrinology"},{"key":"5132_CR11","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1007\/BF02246059","volume":"119","author":"MA Gerrits","year":"1995","unstructured":"Gerrits MA, Patkina N, Zvartau EE, van Ree JM (1995) Opioid blockade attenuates acquisition and expression of cocaine-induced place preference conditioning in rats. Psychopharmacology 119:92\u201398","journal-title":"Psychopharmacology"},{"key":"5132_CR12","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1016\/j.biopsych.2010.05.003","volume":"68","author":"UE Ghitza","year":"2010","unstructured":"Ghitza UE, Preston KL, Epstein DH, Kuwabara H, Endres CJ, Bencherif B, Boyd SJ, Copersino ML, Frost JJ, Gorelick DA (2010) Brain mu-opioid receptor binding predicts treatment outcome in cocaine-abusing outpatients. Biol Psychiatry 68:697\u2013703","journal-title":"Biol Psychiatry"},{"key":"5132_CR13","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1007\/s00213-012-2949-9","volume":"227","author":"C Giuliano","year":"2013","unstructured":"Giuliano C, Robbins TW, Wille DR, Bullmore ET, Everitt BJ (2013) Attenuation of cocaine and heroin seeking by mu-opioid receptor antagonism. Psychopharmacology 227:137\u2013147","journal-title":"Psychopharmacology"},{"key":"5132_CR14","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.1016\/j.biopsych.2005.02.026","volume":"57","author":"DA Gorelick","year":"2005","unstructured":"Gorelick DA, Kim YK, Bencherif B, Boyd SJ, Nelson R, Copersino M, Endres CJ, Dannals RF, Frost JJ (2005) Imaging brain mu-opioid receptors in abstinent cocaine users: time course and relation to cocaine craving. Biol Psychiatry 57:1573\u20131582","journal-title":"Biol Psychiatry"},{"key":"5132_CR15","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.brainres.2014.05.039","volume":"1575","author":"GF Guerin","year":"2014","unstructured":"Guerin GF, Schmoutz CD, Goeders NE (2014) The extra-adrenal effects of metyrapone and oxazepam on ongoing cocaine self-administration. Brain Res 1575:45\u201354","journal-title":"Brain Res"},{"key":"5132_CR16","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.molbrainres.2003.10.024","volume":"121","author":"FS Hall","year":"2004","unstructured":"Hall FS, Goeb M, Li XF, Sora I, Uhl GR (2004) Mu-opioid receptor knockout mice display reduced cocaine conditioned place preference but enhanced sensitization of cocaine-induced locomotion. Brain Res Mol Brain Res 121:123\u2013130","journal-title":"Brain Res Mol Brain Res"},{"key":"5132_CR17","first-page":"29","volume":"2","author":"NL Johnson","year":"2011","unstructured":"Johnson NL, Carini L, Schenk ME, Stewart M, Byrnes EM (2011) Adolescent opiate exposure in the female rat induces subtle alterations in maternal care and transgenerational effects on play behavior. Front Psychiatry 2:29","journal-title":"Front Psychiatry"},{"key":"5132_CR18","doi-asserted-by":"publisher","first-page":"719","DOI":"10.15585\/mmwr.mm6430a5","volume":"64","author":"CM Jones","year":"2015","unstructured":"Jones CM, Logan J, Gladden RM, Bohm MK (2015) Vital signs: demographic and substance use trends among heroin users\u2014United States, 2002-2013. MMWR Morb Mortal Wkly Rep 64:719\u2013725","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"5132_CR19","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1111\/adb.12513","volume":"23","author":"M Kallupi","year":"2018","unstructured":"Kallupi M, Shen Q, de Guglielmo G, Yasuda D, Journigan VB, Zaveri NT, Ciccocioppo R (2018) Buprenorphine requires concomitant activation of NOP and MOP receptors to reduce cocaine consumption. Addict Biol 23:585\u2013595","journal-title":"Addict Biol"},{"key":"5132_CR20","doi-asserted-by":"publisher","first-page":"3201","DOI":"10.1007\/s00213-016-4368-9","volume":"233","author":"RT Lacy","year":"2016","unstructured":"Lacy RT, Strickland JC, Feinstein MA, Robinson AM, Smith MA (2016) The effects of sex, estrous cycle, and social contact on cocaine and heroin self-administration in rats. Psychopharmacology 233:3201\u20133210","journal-title":"Psychopharmacology"},{"key":"5132_CR21","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1007\/s002130000488","volume":"152","author":"WJ Lynch","year":"2000","unstructured":"Lynch WJ, Arizzi MN, Carroll ME (2000) Effects of sex and the estrous cycle on regulation of intravenously self-administered cocaine in rats. Psychopharmacology 152:132\u2013139","journal-title":"Psychopharmacology"},{"issue":"Pt B","key":"5132_CR22","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.neuropharm.2013.07.021","volume":"76","author":"JR Mantsch","year":"2014","unstructured":"Mantsch JR, Vranjkovic O, Twining RC, Gasser PJ, McReynolds JR, Blacktop JM (2014) Neurobiological mechanisms that contribute to stress-related cocaine use. Neuropharmacology 76(Pt B):383\u2013394","journal-title":"Neuropharmacology"},{"key":"5132_CR23","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/S0893-133X(96)00169-8","volume":"16","author":"M Marinelli","year":"1997","unstructured":"Marinelli M, Rouge-Pont F, De Jesus-Oliveira C, Le Moal M, Piazza PV (1997a) Acute blockade of corticosterone secretion decreases the psychomotor stimulant effects of cocaine. Neuropsychopharmacology 16:156\u2013161","journal-title":"Neuropsychopharmacology"},{"key":"5132_CR24","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1016\/S0022-3565(24)36711-4","volume":"281","author":"M Marinelli","year":"1997","unstructured":"Marinelli M, Rouge-Pont F, Deroche V, Barrot M, De Jesus-Oliveira C, Le Moal M, Piazza PV (1997b) Glucocorticoids and behavioral effects of psychostimulants. I: locomotor response to cocaine depends on basal levels of glucocorticoids. J Pharmacol Exp Ther 281:1392\u20131400","journal-title":"J Pharmacol Exp Ther"},{"key":"5132_CR25","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/s00213-007-1053-z","volume":"197","author":"P Marquez","year":"2008","unstructured":"Marquez P, Baliram R, Dabaja I, Gajawada N, Lutfy K (2008) The role of beta-endorphin in the acute motor stimulatory and rewarding actions of cocaine in mice. Psychopharmacology 197:443\u2013448","journal-title":"Psychopharmacology"},{"key":"5132_CR26","doi-asserted-by":"crossref","unstructured":"McReynolds JR, Doncheck EM, Li Y, Vranjkovic O, Graf EN, Ogasawara D, Cravatt BF, Baker DA, Liu QS, Hillard CJ, Mantsch JR, 2017a. Stress promotes drug seeking through glucocorticoid-dependent endocannabinoid mobilization in the prelimbic cortex. Biol Psychiatry","DOI":"10.1016\/j.biopsych.2017.09.024"},{"key":"5132_CR27","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1038\/npp.2016.187","volume":"42","author":"JR McReynolds","year":"2017","unstructured":"McReynolds JR, Taylor A, Vranjkovic O, Ambrosius T, Derricks O, Nino B, Kurtoglu B, Wheeler RA, Baker DA, Gasser PJ, Mantsch JR (2017b) Corticosterone potentiation of cocaine-induced reinstatement of conditioned place preference in mice is mediated by blockade of the organic cation transporter 3. Neuropsychopharmacology 42:757\u2013765","journal-title":"Neuropsychopharmacology"},{"key":"5132_CR28","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.ejphar.2012.04.040","volume":"686","author":"AT Nguyen","year":"2012","unstructured":"Nguyen AT, Marquez P, Hamid A, Kieffer B, Friedman TC, Lutfy K (2012) The rewarding action of acute cocaine is reduced in beta-endorphin deficient but not in mu opioid receptor knockout mice. Eur J Pharmacol 686:50\u201354","journal-title":"Eur J Pharmacol"},{"key":"5132_CR29","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1038\/nrn3939","volume":"16","author":"DJ Nutt","year":"2015","unstructured":"Nutt DJ, Lingford-Hughes A, Erritzoe D, Stokes PR (2015) The dopamine theory of addiction: 40 years of highs and lows. Nat Rev Neurosci 16:305\u2013312","journal-title":"Nat Rev Neurosci"},{"key":"5132_CR30","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1124\/pr.112.007138","volume":"65","author":"GW Pasternak","year":"2013","unstructured":"Pasternak GW, Pan YX (2013) Mu opioids and their receptors: evolution of a concept. Pharmacol Rev 65:1257\u20131317","journal-title":"Pharmacol Rev"},{"key":"5132_CR31","volume-title":"The rat brain in stereotaxic coordinates","author":"G Paxinos","year":"1997","unstructured":"Paxinos G, Watson C (1997) The rat brain in stereotaxic coordinates. Academic, New York"},{"key":"5132_CR32","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.neubiorev.2005.04.016","volume":"30","author":"RC Pierce","year":"2006","unstructured":"Pierce RC, Kumaresan V (2006) The mesolimbic dopamine system: the final common pathway for the reinforcing effect of drugs of abuse? Neurosci Biobehav Rev 30:215\u2013238","journal-title":"Neurosci Biobehav Rev"},{"key":"5132_CR33","doi-asserted-by":"publisher","first-page":"5647","DOI":"10.2174\/092986712803988811","volume":"19","author":"C Pomara","year":"2012","unstructured":"Pomara C, Cassano T, D'Errico S, Bello S, Romano AD, Riezzo I, Serviddio G (2012) Data available on the extent of cocaine use and dependence: biochemistry, pharmacologic effects and global burden of disease of cocaine abusers. Curr Med Chem 19:5647\u20135657","journal-title":"Curr Med Chem"},{"key":"5132_CR34","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/0091-3057(91)90090-O","volume":"40","author":"NF Ramsey","year":"1991","unstructured":"Ramsey NF, van Ree JM (1991) Intracerebroventricular naltrexone treatment attenuates acquisition of intravenous cocaine self-administration in rats. Pharmacol Biochem Behav 40:807\u2013810","journal-title":"Pharmacol Biochem Behav"},{"key":"5132_CR35","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s13072-018-0192-2","volume":"11","author":"J Ren","year":"2018","unstructured":"Ren J, Cheng Y, Ming ZH, Dong XY, Zhou YZ, Ding GL, Pang HY, Rahman TU, Akbar R, Huang HF, Sheng JZ (2018) Intrauterine hyperglycemia exposure results in intergenerational inheritance via DNA methylation reprogramming on F1 PGCs. Epigenetics Chromatin 11:20","journal-title":"Epigenetics Chromatin"},{"key":"5132_CR36","doi-asserted-by":"publisher","first-page":"9003","DOI":"10.1523\/JNEUROSCI.0914-13.2013","volume":"33","author":"AB Rodgers","year":"2013","unstructured":"Rodgers AB, Morgan CP, Bronson SL, Revello S, Bale TL (2013) Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation. J Neurosci 33:9003\u20139012","journal-title":"J Neurosci"},{"key":"5132_CR37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.pneurobio.2008.06.003","volume":"86","author":"I Roth-Deri","year":"2008","unstructured":"Roth-Deri I, Green-Sadan T, Yadid G (2008) Beta-endorphin and drug-induced reward and reinforcement. Prog Neurobiol 86:1\u201321","journal-title":"Prog Neurobiol"},{"key":"5132_CR38","doi-asserted-by":"publisher","first-page":"1378","DOI":"10.15585\/mmwr.mm6450a3","volume":"64","author":"RA Rudd","year":"2016","unstructured":"Rudd RA, Aleshire N, Zibbell JE, Gladden RM (2016) Increases in drug and opioid overdose deaths\u2014United States, 2000-2014. MMWR Morb Mortal Wkly Rep 64:1378\u20131382","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"5132_CR39","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1038\/npp.2009.28","volume":"34","author":"D Simmons","year":"2009","unstructured":"Simmons D, Self DW (2009) Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior. Neuropsychopharmacology 34:1946\u20131957","journal-title":"Neuropsychopharmacology"},{"key":"5132_CR40","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.neuropharm.2017.05.022","volume":"123","author":"SJ Stringfield","year":"2017","unstructured":"Stringfield SJ, Higginbotham JA, Wang R, Berger AL, McLaughlin RJ, Fuchs RA (2017) Role of glucocorticoid receptor-mediated mechanisms in cocaine memory enhancement. Neuropharmacology 123:349\u2013358","journal-title":"Neuropharmacology"},{"key":"5132_CR41","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s00213-010-1812-0","volume":"210","author":"W Sun","year":"2010","unstructured":"Sun W, Xue Y, Huang Z, Steketee JD (2010) Regulation of cocaine-reinstated drug-seeking behavior by kappa-opioid receptors in the ventral tegmental area of rats. Psychopharmacology 210:179\u2013188","journal-title":"Psychopharmacology"},{"key":"5132_CR42","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1254\/jjp.58.435","volume":"58","author":"T Suzuki","year":"1992","unstructured":"Suzuki T, Shiozaki Y, Masukawa Y, Misawa M, Nagase H (1992) The role of mu- and kappa-opioid receptors in cocaine-induced conditioned place preference. Jpn J Pharmacol 58:435\u2013442","journal-title":"Jpn J Pharmacol"},{"key":"5132_CR43","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1111\/j.1749-6632.2001.tb03559.x","volume":"937","author":"EM Unterwald","year":"2001","unstructured":"Unterwald EM (2001) Regulation of opioid receptors by cocaine. Ann N Y Acad Sci 937:74\u201392","journal-title":"Ann N Y Acad Sci"},{"issue":"Pt B","key":"5132_CR44","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.neuropharm.2013.06.016","volume":"76","author":"FM Vassoler","year":"2014","unstructured":"Vassoler FM, Byrnes EM, Pierce RC (2014a) The impact of exposure to addictive drugs on future generations: physiological and behavioral effects. Neuropharmacology 76(Pt B):269\u2013275","journal-title":"Neuropharmacology"},{"key":"5132_CR45","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1097\/FBP.0000000000000032","volume":"25","author":"FM Vassoler","year":"2014","unstructured":"Vassoler FM, Johnson-Collins NL, Carini LM, Byrnes EM (2014b) Next generation effects of female adolescent morphine exposure: sex-specific alterations in response to acute morphine emerge before puberty. Behav Pharmacol 25:173\u2013181","journal-title":"Behav Pharmacol"},{"key":"5132_CR46","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.neuropharm.2016.10.006","volume":"113","author":"FM Vassoler","year":"2017","unstructured":"Vassoler FM, Oliver DJ, Wyse C, Blau A, Shtutman M, Turner JR, Byrnes EM (2017) Transgenerational attenuation of opioid self-administration as a consequence of adolescent morphine exposure. Neuropharmacology 113:271\u2013280","journal-title":"Neuropharmacology"},{"key":"5132_CR47","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1016\/j.neuroscience.2013.07.064","volume":"264","author":"FM Vassoler","year":"2014","unstructured":"Vassoler FM, Sadri-Vakili G (2014) Mechanisms of transgenerational inheritance of addictive-like behaviors. Neuroscience 264:198\u2013206","journal-title":"Neuroscience"},{"key":"5132_CR48","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.brainres.2017.11.004","volume":"1679","author":"FM Vassoler","year":"2018","unstructured":"Vassoler FM, Toorie AM, Byrnes EM (2018) Transgenerational blunting of morphine-induced corticosterone secretion is associated with dysregulated gene expression in male offspring. Brain Res 1679:19\u201325","journal-title":"Brain Res"},{"key":"5132_CR49","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1038\/nn.3280","volume":"16","author":"FM Vassoler","year":"2013","unstructured":"Vassoler FM, White SL, Schmidt HD, Sadri-Vakili G, Pierce RC (2013) Epigenetic inheritance of a cocaine-resistance phenotype. Nat Neurosci 16:42\u201347","journal-title":"Nat Neurosci"},{"key":"5132_CR50","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.neuropharm.2015.11.026","volume":"103","author":"FM Vassoler","year":"2016","unstructured":"Vassoler FM, Wright SJ, Byrnes EM (2016) Exposure to opiates in female adolescents alters mu opiate receptor expression and increases the rewarding effects of morphine in future offspring. Neuropharmacology 103:112\u2013121","journal-title":"Neuropharmacology"},{"key":"5132_CR51","doi-asserted-by":"publisher","first-page":"2638","DOI":"10.1111\/ejn.13730","volume":"46","author":"DS Wheeler","year":"2017","unstructured":"Wheeler DS, Ebben AL, Kurtoglu B, Lovell ME, Bohn AT, Jasek IA, Baker DA, Mantsch JR, Gasser PJ, Wheeler RA (2017) Corticosterone regulates both naturally occurring and cocaine-induced dopamine signaling by selectively decreasing dopamine uptake. Eur J Neurosci 46:2638\u20132646","journal-title":"Eur J Neurosci"},{"key":"5132_CR52","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.pbiomolbio.2015.03.002","volume":"118","author":"NL Yohn","year":"2015","unstructured":"Yohn NL, Bartolomei MS, Blendy JA (2015) Multigenerational and transgenerational inheritance of drug exposure: the effects of alcohol, opiates, cocaine, marijuana, and nicotine. Prog Biophys Mol Biol 118:21\u201333","journal-title":"Prog Biophys Mol Biol"},{"key":"5132_CR53","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1038\/s41586-018-0239-3","volume":"558","author":"R Yu","year":"2018","unstructured":"Yu R, Wang X, Moazed D (2018) Epigenetic inheritance mediated by coupling of RNAi and histone H3K9 methylation. Nature 558:615\u2013619","journal-title":"Nature"},{"key":"5132_CR54","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.neuroscience.2014.12.078","volume":"289","author":"Y Zhou","year":"2015","unstructured":"Zhou Y, Kreek MJ (2015) Persistent increases in rat hypothalamic POMC gene expression following chronic withdrawal from chronic \u201cbinge\u201d pattern escalating-dose, but not steady-dose, cocaine. Neuroscience 289:63\u201370","journal-title":"Neuroscience"},{"key":"5132_CR55","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.neulet.2012.09.060","volume":"530","author":"Y Zhou","year":"2012","unstructured":"Zhou Y, Kruyer A, Ho A, Kreek MJ (2012) Cocaine place conditioning increases pro-opiomelanocortin gene expression in rat hypothalamus. Neurosci Lett 530:59\u201363","journal-title":"Neurosci Lett"},{"key":"5132_CR56","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1038\/nm1196-1225","volume":"2","author":"JK Zubieta","year":"1996","unstructured":"Zubieta JK, Gorelick DA, Stauffer R, Ravert HT, Dannals RF, Frost JJ (1996) Increased mu opioid receptor binding detected by PET in cocaine-dependent men is associated with cocaine craving. Nat Med 2:1225\u20131229","journal-title":"Nat Med"}],"container-title":["Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00213-018-5132-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00213-018-5132-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00213-018-5132-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T07:29:32Z","timestamp":1775287772000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00213-018-5132-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,30]]},"references-count":56,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["5132"],"URL":"https:\/\/doi.org\/10.1007\/s00213-018-5132-0","relation":{},"ISSN":["0033-3158","1432-2072"],"issn-type":[{"value":"0033-3158","type":"print"},{"value":"1432-2072","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,30]]},"assertion":[{"value":"10 July 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 November 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 November 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}