{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:54:52Z","timestamp":1791464092719,"version":"4.3.4"},"reference-count":114,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2020,8,10]],"date-time":"2020-08-10T00:00:00Z","timestamp":1597017600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,10]],"date-time":"2020-08-10T00:00:00Z","timestamp":1597017600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH114296"],"award-info":[{"award-number":["MH114296"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Psychopharmacology"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s00213-020-05635-4","type":"journal-article","created":{"date-parts":[[2020,8,10]],"date-time":"2020-08-10T12:03:29Z","timestamp":1597061009000},"page":"3553-3568","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Altered baseline and amphetamine-mediated behavioral profiles in dopamine transporter Cre (DAT-Ires-Cre) mice compared to tyrosine hydroxylase Cre (TH-Cre) mice"],"prefix":"10.1007","volume":"237","author":[{"given":"Muhammad O.","family":"Chohan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sari","family":"Esses","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Haft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne E.","family":"Ahmari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6349-1076","authenticated-orcid":false,"given":"Jeremy","family":"Veenstra-VanderWeele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,8,10]]},"reference":[{"key":"5635_CR1","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.neulet.2008.07.075","volume":"443","author":"U Abramov","year":"2008","unstructured":"Abramov U, Puussaar T, Raud S, Kurrikoff K, Vasar E (2008) Behavioural differences between C57BL\/6 and 129S6\/SvEv strains are reinforced by environmental enrichment. Neurosci Lett 443:223\u2013227. https:\/\/doi.org\/10.1016\/j.neulet.2008.07.075","journal-title":"Neurosci Lett"},{"key":"5635_CR2","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/0169-328x(93)90059-x","volume":"20","author":"SJ Augood","year":"1993","unstructured":"Augood SJ, Westmore K, McKenna PJ, Emson PC (1993) Co-expression of dopamine transporter mRNA and tyrosine hydroxylase mRNA in ventral mesencephalic neurones. Brain Res Mol Brain Res 20:328\u2013334. https:\/\/doi.org\/10.1016\/0169-328x(93)90059-x","journal-title":"Brain Res Mol Brain Res"},{"key":"5635_CR3","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1002\/dvg.20228","volume":"44","author":"CM Backman","year":"2006","unstructured":"Backman CM et al (2006) Characterization of a mouse strain expressing Cre recombinase from the 3\u2032 untranslated region of the dopamine transporter locus. Genesis 44:383\u2013390. https:\/\/doi.org\/10.1002\/dvg.20228","journal-title":"Genesis"},{"key":"5635_CR4","doi-asserted-by":"publisher","first-page":"3173","DOI":"10.1038\/s41467-018-05382-3","volume":"9","author":"S Bariselli","year":"2018","unstructured":"Bariselli S, Hornberg H, Prevost-Solie C, Musardo S, Hatstatt-Burkle L, Scheiffele P, Bellone C (2018) Role of VTA dopamine neurons and neuroligin 3 in sociability traits related to nonfamiliar conspecific interaction. Nat Commun 9:3173. https:\/\/doi.org\/10.1038\/s41467-018-05382-3","journal-title":"Nat Commun"},{"key":"5635_CR5","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1016\/j.cell.2015.07.015","volume":"162","author":"KT Beier","year":"2015","unstructured":"Beier KT, Steinberg EE, DeLoach KE, Xie S, Miyamichi K, Schwarz L, Gao XJ, Kremer EJ, Malenka RC, Luo L (2015) Circuit architecture of vta dopamine neurons revealed by systematic input-output mapping. Cell 162:622\u2013634. https:\/\/doi.org\/10.1016\/j.cell.2015.07.015","journal-title":"Cell"},{"key":"5635_CR6","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1038\/nn.2862","volume":"14","author":"EP Bello","year":"2011","unstructured":"Bello EP et al (2011) Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors. Nat Neurosci 14:1033\u20131038. https:\/\/doi.org\/10.1038\/nn.2862","journal-title":"Nat Neurosci"},{"key":"5635_CR7","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1038\/s41593-018-0152-y","volume":"21","author":"JD Berke","year":"2018","unstructured":"Berke JD (2018) What does dopamine mean? Nat Neurosci 21:787\u2013793. https:\/\/doi.org\/10.1038\/s41593-018-0152-y","journal-title":"Nat Neurosci"},{"key":"5635_CR8","doi-asserted-by":"publisher","first-page":"4206","DOI":"10.1073\/pnas.1101424108","volume":"108","author":"LR Beutler","year":"2011","unstructured":"Beutler LR, Wanat MJ, Quintana A, Sanz E, Bamford NS, Zweifel LS, Palmiter RD (2011) Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization. Proc Natl Acad Sci U S A 108:4206\u20134211. https:\/\/doi.org\/10.1073\/pnas.1101424108","journal-title":"Proc Natl Acad Sci U S A"},{"key":"5635_CR9","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.tins.2007.03.006","volume":"30","author":"A Bjorklund","year":"2007","unstructured":"Bjorklund A, Dunnett SB (2007) Dopamine neuron systems in the brain: an update. Trends Neurosci 30:194\u2013202. https:\/\/doi.org\/10.1016\/j.tins.2007.03.006","journal-title":"Trends Neurosci"},{"key":"5635_CR10","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/s1534-5807(03)00399-x","volume":"6","author":"CS Branda","year":"2004","unstructured":"Branda CS, Dymecki SM (2004) Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice. Dev Cell 6:7\u201328. https:\/\/doi.org\/10.1016\/s1534-5807(03)00399-x","journal-title":"Dev Cell"},{"key":"5635_CR11","doi-asserted-by":"publisher","first-page":"4633","DOI":"10.1038\/s41467-019-12392-2","volume":"10","author":"DF Cardozo Pinto","year":"2019","unstructured":"Cardozo Pinto DF, Yang H, Pollak Dorocic I, de Jong JW, Han VJ, Peck JR, Zhu Y, Liu C, Beier KT, Smidt MP, Lammel S (2019) Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe. Nat Commun 10:4633. https:\/\/doi.org\/10.1038\/s41467-019-12392-2","journal-title":"Nat Commun"},{"key":"5635_CR12","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1159\/000336824","volume":"34","author":"AC Carpenter","year":"2012","unstructured":"Carpenter AC, Saborido TP, Stanwood GD (2012) Development of hyperactivity and anxiety responses in dopamine transporter-deficient mice. Dev Neurosci 34:250\u2013257. https:\/\/doi.org\/10.1159\/000336824","journal-title":"Dev Neurosci"},{"key":"5635_CR13","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1038\/nature11713","volume":"493","author":"D Chaudhury","year":"2013","unstructured":"Chaudhury D et al (2013) Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature 493:532\u2013536. https:\/\/doi.org\/10.1038\/nature11713","journal-title":"Nature"},{"key":"5635_CR14","doi-asserted-by":"publisher","first-page":"2177","DOI":"10.1523\/JNEUROSCI.1433-17.2018","volume":"38","author":"E Chen","year":"2018","unstructured":"Chen E, Lallai V, Sherafat Y, Grimes NP, Pushkin AN, Fowler JP, Fowler CD (2018) Altered baseline and nicotine-mediated behavioral and cholinergic profiles in ChAT-Cre mouse. Lines J Neurosci 38:2177\u20132188. https:\/\/doi.org\/10.1523\/JNEUROSCI.1433-17.2018","journal-title":"Lines J Neurosci"},{"key":"5635_CR15","doi-asserted-by":"publisher","first-page":"9333","DOI":"10.1073\/pnas.0600905103","volume":"103","author":"R Chen","year":"2006","unstructured":"Chen R et al (2006) Abolished cocaine reward in mice with a cocaine-insensitive dopamine transporter. Proc Natl Acad Sci U S A 103:9333\u20139338. https:\/\/doi.org\/10.1073\/pnas.0600905103","journal-title":"Proc Natl Acad Sci U S A"},{"key":"5635_CR16","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/0165-3806(96)00123-x","volume":"96","author":"WS Choi","year":"1996","unstructured":"Choi WS, Ronnekleiv OK (1996) Effects of in utero cocaine exposure on the expression of mRNAS encoding the dopamine transporter and the D1, D2 and D5 dopamine receptor subtypes in fetal rhesus monkey. Brain Res Dev Brain Res 96:249\u2013260. https:\/\/doi.org\/10.1016\/0165-3806(96)00123-x","journal-title":"Brain Res Dev Brain Res"},{"key":"5635_CR17","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1523\/JNEUROSCI.15-03-01714.1995","volume":"15","author":"BJ Ciliax","year":"1995","unstructured":"Ciliax BJ, Heilman C, Demchyshyn LL, Pristupa ZB, Ince E, Hersch SM, Niznik HB, Levey AI (1995) The dopamine transporter: immunochemical characterization and localization in brain. J Neurosci 15:1714\u20131723","journal-title":"J Neurosci"},{"key":"5635_CR18","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1038\/nature10754","volume":"482","author":"JY Cohen","year":"2012","unstructured":"Cohen JY, Haesler S, Vong L, Lowell BB, Uchida N (2012) Neuron-type-specific signals for reward and punishment in the ventral tegmental area. Nature 482:85\u201388. https:\/\/doi.org\/10.1038\/nature10754","journal-title":"Nature"},{"key":"5635_CR19","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1111\/j.1399-5618.2009.00760.x","volume":"11","author":"DA Cousins","year":"2009","unstructured":"Cousins DA, Butts K, Young AH (2009) The role of dopamine in bipolar disorder. Bipolar Disord 11:787\u2013806. https:\/\/doi.org\/10.1111\/j.1399-5618.2009.00760.x","journal-title":"Bipolar Disord"},{"key":"5635_CR20","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.1126\/science.284.5420.1670","volume":"284","author":"JC Crabbe","year":"1999","unstructured":"Crabbe JC, Wahlsten D, Dudek BC (1999) Genetics of mouse behavior: interactions with laboratory environment. Science 284:1670\u20131672. https:\/\/doi.org\/10.1126\/science.284.5420.1670","journal-title":"Science"},{"key":"5635_CR21","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3389\/fncir.2014.00057","volume":"8","author":"JR Crittenden","year":"2014","unstructured":"Crittenden JR, Lacey CJ, Lee T, Bowden HA, Graybiel AM (2014) Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice. Front Neural Circuits 8:57. https:\/\/doi.org\/10.3389\/fncir.2014.00057","journal-title":"Front Neural Circuits"},{"key":"5635_CR22","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.biopsych.2003.12.026","volume":"56","author":"WE Crusio","year":"2004","unstructured":"Crusio WE (2004) Flanking gene and genetic background problems in genetically manipulated mice. Biol Psychiatry 56:381\u2013385. https:\/\/doi.org\/10.1016\/j.biopsych.2003.12.026","journal-title":"Biol Psychiatry"},{"key":"5635_CR23","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1038\/nature25457","volume":"554","author":"JA da Silva","year":"2018","unstructured":"da Silva JA, Tecuapetla F, Paixao V, Costa RM (2018) Dopamine neuron activity before action initiation gates and invigorates future movements. Nature 554:244\u2013248. https:\/\/doi.org\/10.1038\/nature25457","journal-title":"Nature"},{"key":"5635_CR24","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1038\/s41586-019-1924-6","volume":"577","author":"W Dabney","year":"2020","unstructured":"Dabney W, Kurth-Nelson Z, Uchida N, Starkweather CK, Hassabis D, Munos R, Botvinick M (2020) A distributional code for value in dopamine-based reinforcement learning. Nature 577:671\u2013675. https:\/\/doi.org\/10.1038\/s41586-019-1924-6","journal-title":"Nature"},{"key":"5635_CR25","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1016\/j.euroneuro.2013.05.012","volume":"23","author":"D Denys","year":"2013","unstructured":"Denys D et al (2013) Dopaminergic activity in Tourette syndrome and obsessive-compulsive disorder. Eur Neuropsychopharmacol 23:1423\u20131431. https:\/\/doi.org\/10.1016\/j.euroneuro.2013.05.012","journal-title":"Eur Neuropsychopharmacol"},{"issue":"Suppl 14","key":"5635_CR26","first-page":"11","volume":"65","author":"D Denys","year":"2004","unstructured":"Denys D, Zohar J, Westenberg HG (2004) The role of dopamine in obsessive-compulsive disorder: preclinical and clinical evidence. J Clin Psychiatry 65(Suppl 14):11\u201317","journal-title":"J Clin Psychiatry"},{"key":"5635_CR27","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1101\/lm.026716.112","volume":"19","author":"O Diaz-Ruiz","year":"2012","unstructured":"Diaz-Ruiz O et al (2012) Attenuated response to methamphetamine sensitization and deficits in motor learning and memory after selective deletion of beta-catenin in dopamine neurons. Learn Mem 19:341\u2013350. https:\/\/doi.org\/10.1101\/lm.026716.112","journal-title":"Learn Mem"},{"key":"5635_CR28","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.1073\/pnas.97.4.1879","volume":"97","author":"B Dumartin","year":"2000","unstructured":"Dumartin B, Jaber M, Gonon F, Caron MG, Giros B, Bloch B (2000) Dopamine tone regulates D1 receptor trafficking and delivery in striatal neurons in dopamine transporter-deficient mice. Proc Natl Acad Sci U S A 97:1879\u20131884. https:\/\/doi.org\/10.1073\/pnas.97.4.1879","journal-title":"Proc Natl Acad Sci U S A"},{"key":"5635_CR29","doi-asserted-by":"publisher","first-page":"2465","DOI":"10.1126\/science.1060645","volume":"293","author":"BH Falkenburger","year":"2001","unstructured":"Falkenburger BH, Barstow KL, Mintz IM (2001) Dendrodendritic inhibition through reversal of dopamine transport. Science 293:2465\u20132470. https:\/\/doi.org\/10.1126\/science.1060645","journal-title":"Science"},{"key":"5635_CR30","doi-asserted-by":"publisher","first-page":"9593","DOI":"10.1523\/JNEUROSCI.2815-06.2006","volume":"26","author":"PE Forni","year":"2006","unstructured":"Forni PE et al (2006) High levels of Cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly. J Neurosci 26:9593\u20139602. https:\/\/doi.org\/10.1523\/JNEUROSCI.2815-06.2006","journal-title":"J Neurosci"},{"key":"5635_CR31","doi-asserted-by":"publisher","first-page":"10652","DOI":"10.1038\/ncomms10652","volume":"7","author":"Z Freyberg","year":"2016","unstructured":"Freyberg Z, Sonders MS, Aguilar JI, Hiranita T, Karam CS, Flores J, Pizzo AB, Zhang Y, Farino ZJ, Chen A, Martin CA, Kopajtic TA, Fei H, Hu G, Lin YY, Mosharov EV, McCabe BD, Freyberg R, Wimalasena K, Hsin LW, Sames D, Krantz DE, Katz JL, Sulzer D, Javitch JA (2016) Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain. Nat Commun 7:10652. https:\/\/doi.org\/10.1038\/ncomms10652","journal-title":"Nat Commun"},{"key":"5635_CR32","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1126\/science.1249240","volume":"344","author":"AK Friedman","year":"2014","unstructured":"Friedman AK et al (2014) Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience. Science 344:313\u2013319. https:\/\/doi.org\/10.1126\/science.1249240","journal-title":"Science"},{"key":"5635_CR33","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1126\/science.283.5400.397","volume":"283","author":"RR Gainetdinov","year":"1999","unstructured":"Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG (1999) Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 283:397\u2013401. https:\/\/doi.org\/10.1126\/science.283.5400.397","journal-title":"Science"},{"key":"5635_CR34","doi-asserted-by":"publisher","first-page":"e11443","DOI":"10.1371\/journal.pone.0011443","volume":"5","author":"C Galichet","year":"2010","unstructured":"Galichet C, Lovell-Badge R, Rizzoti K (2010) Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland. PLoS One 5:e11443. https:\/\/doi.org\/10.1371\/journal.pone.0011443","journal-title":"PLoS One"},{"key":"5635_CR35","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/s0166-2236(96)20020-7","volume":"19","author":"R Gerlai","year":"1996","unstructured":"Gerlai R (1996) Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci 19:177\u2013181. https:\/\/doi.org\/10.1016\/s0166-2236(96)20020-7","journal-title":"Trends Neurosci"},{"key":"5635_CR36","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/0165-6147(93)90029-j","volume":"14","author":"B Giros","year":"1993","unstructured":"Giros B, Caron MG (1993) Molecular characterization of the dopamine transporter. Trends Pharmacol Sci 14:43\u201349. https:\/\/doi.org\/10.1016\/0165-6147(93)90029-j","journal-title":"Trends Pharmacol Sci"},{"key":"5635_CR37","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1038\/379606a0","volume":"379","author":"B Giros","year":"1996","unstructured":"Giros B, Jaber M, Jones SR, Wightman RM, Caron MG (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379:606\u2013612. https:\/\/doi.org\/10.1038\/379606a0","journal-title":"Nature"},{"key":"5635_CR38","doi-asserted-by":"publisher","first-page":"152","DOI":"10.3389\/fnbeh.2015.00152","volume":"9","author":"HS Gompf","year":"2015","unstructured":"Gompf HS, Budygin EA, Fuller PM, Bass CE (2015) Targeted genetic manipulations of neuronal subtypes using promoter-specific combinatorial AAVs in wild-type animals. Front Behav Neurosci 9:152. https:\/\/doi.org\/10.3389\/fnbeh.2015.00152","journal-title":"Front Behav Neurosci"},{"key":"5635_CR39","doi-asserted-by":"publisher","first-page":"1535","DOI":"10.1016\/j.cell.2014.05.017","volume":"157","author":"LA Gunaydin","year":"2014","unstructured":"Gunaydin LA et al (2014) Natural neural projection dynamics underlying social behavior. Cell 157:1535\u20131551. https:\/\/doi.org\/10.1016\/j.cell.2014.05.017","journal-title":"Cell"},{"key":"5635_CR40","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1038\/mp.2013.102","volume":"18","author":"PJ Hamilton","year":"2013","unstructured":"Hamilton PJ et al (2013) De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder. Mol Psychiatry 18:1315\u20131323. https:\/\/doi.org\/10.1038\/mp.2013.102","journal-title":"Mol Psychiatry"},{"key":"5635_CR41","first-page":"427","volume":"54","author":"T Hokfelt","year":"1976","unstructured":"Hokfelt T, Johansson O, Fuxe K, Goldstein M, Park D (1976) Immunohistochemical studies on the localization and distribution of monoamine neuron systems in the rat brain. I. Tyrosine hydroxylase in the mes- and diencephalon. Med Biol 54:427\u2013453","journal-title":"Med Biol"},{"key":"5635_CR42","first-page":"21","volume":"55","author":"T Hokfelt","year":"1977","unstructured":"Hokfelt T, Johansson O, Fuxe K, Goldstein M, Park D (1977) Immunohistochemical studies on the localization and distribution of monoamine neuron systems in the rat brain II. Tyrosine hydroxylase in the telencephalon. Med Biol 55:21\u201340","journal-title":"Med Biol"},{"key":"5635_CR43","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1038\/nature09263","volume":"466","author":"X Jin","year":"2010","unstructured":"Jin X, Costa RM (2010) Start\/stop signals emerge in nigrostriatal circuits during sequence learning. Nature 466:457\u2013462. https:\/\/doi.org\/10.1038\/nature09263","journal-title":"Nature"},{"key":"5635_CR44","doi-asserted-by":"publisher","first-page":"4029","DOI":"10.1073\/pnas.95.7.4029","volume":"95","author":"SR Jones","year":"1998","unstructured":"Jones SR, Gainetdinov RR, Jaber M, Giros B, Wightman RM, Caron MG (1998a) Profound neuronal plasticity in response to inactivation of the dopamine transporter. Proc Natl Acad Sci U S A 95:4029\u20134034. https:\/\/doi.org\/10.1073\/pnas.95.7.4029","journal-title":"Proc Natl Acad Sci U S A"},{"key":"5635_CR45","doi-asserted-by":"publisher","first-page":"1979","DOI":"10.1523\/JNEUROSCI.18-06-01979.1998","volume":"18","author":"SR Jones","year":"1998","unstructured":"Jones SR, Gainetdinov RR, Wightman RM, Caron MG (1998b) Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter. J Neurosci 18:1979\u20131986","journal-title":"J Neurosci"},{"key":"5635_CR46","doi-asserted-by":"publisher","first-page":"3495","DOI":"10.1073\/pnas.0407737102","volume":"102","author":"KM Kahlig","year":"2005","unstructured":"Kahlig KM, Binda F, Khoshbouei H, Blakely RD, McMahon DG, Javitch JA, Galli A (2005) Amphetamine induces dopamine efflux through a dopamine transporter channel. Proc Natl Acad Sci U S A 102:3495\u20133500. https:\/\/doi.org\/10.1073\/pnas.0407737102","journal-title":"Proc Natl Acad Sci U S A"},{"key":"5635_CR47","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1016\/j.neuroscience.2015.08.036","volume":"321","author":"T Kaiser","year":"2016","unstructured":"Kaiser T, Ting JT, Monteiro P, Feng G (2016) Transgenic labeling of parvalbumin-expressing neurons with tdTomato. Neuroscience 321:236\u2013245. https:\/\/doi.org\/10.1016\/j.neuroscience.2015.08.036","journal-title":"Neuroscience"},{"key":"5635_CR48","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.eplepsyres.2012.10.005","volume":"104","author":"TH Kim","year":"2013","unstructured":"Kim TH, Richards K, Heng J, Petrou S, Reid CA (2013) Two lines of transgenic mice expressing cre-recombinase exhibit increased seizure susceptibility. Epilepsy Res 104:11\u201316. https:\/\/doi.org\/10.1016\/j.eplepsyres.2012.10.005","journal-title":"Epilepsy Res"},{"key":"5635_CR49","doi-asserted-by":"publisher","first-page":"10427","DOI":"10.1523\/JNEUROSCI.0395-13.2013","volume":"33","author":"B Kolisnyk","year":"2013","unstructured":"Kolisnyk B et al (2013) ChAT-ChR2-EYFP mice have enhanced motor endurance but show deficits in attention and several additional cognitive domains. J Neurosci 33:10427\u201310438. https:\/\/doi.org\/10.1523\/JNEUROSCI.0395-13.2013","journal-title":"J Neurosci"},{"key":"5635_CR50","doi-asserted-by":"publisher","first-page":"5426","DOI":"10.1038\/s41467-019-13396-8","volume":"10","author":"P Kosillo","year":"2019","unstructured":"Kosillo P et al (2019) Tsc1-mTORC1 signaling controls striatal dopamine release and cognitive flexibility. Nat Commun 10:5426. https:\/\/doi.org\/10.1038\/s41467-019-13396-8","journal-title":"Nat Commun"},{"key":"5635_CR51","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1523\/JNEUROSCI.4287-10.2011","volume":"31","author":"PF Kramer","year":"2011","unstructured":"Kramer PF et al (2011) Dopamine D2 receptor overexpression alters behavior and physiology in Drd2-EGFP mice. J Neurosci 31:126\u2013132. https:\/\/doi.org\/10.1523\/JNEUROSCI.4287-10.2011","journal-title":"J Neurosci"},{"key":"5635_CR52","doi-asserted-by":"publisher","first-page":"4","DOI":"10.3389\/fncir.2019.00004","volume":"13","author":"A Krol","year":"2019","unstructured":"Krol A, Lopez-Huerta VG, Corey TEC, Deisseroth K, Ting JT, Feng G (2019) Two eARCHT3.0 lines for optogenetic silencing of dopaminergic and serotonergic neurons. front neural circuits 13:4. https:\/\/doi.org\/10.3389\/fncir.2019.00004","journal-title":"front neural circuits"},{"key":"5635_CR53","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1016\/j.neuron.2008.01.022","volume":"57","author":"S Lammel","year":"2008","unstructured":"Lammel S, Hetzel A, Hackel O, Jones I, Liss B, Roeper J (2008) Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. Neuron 57:760\u2013773. https:\/\/doi.org\/10.1016\/j.neuron.2008.01.022","journal-title":"Neuron"},{"key":"5635_CR54","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1038\/nature11527","volume":"491","author":"S Lammel","year":"2012","unstructured":"Lammel S et al (2012) Input-specific control of reward and aversion in the ventral tegmental area. Nature 491:212\u2013217. https:\/\/doi.org\/10.1038\/nature11527","journal-title":"Nature"},{"key":"5635_CR55","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.neuron.2014.12.036","volume":"85","author":"S Lammel","year":"2015","unstructured":"Lammel S, Steinberg EE, Foldy C, Wall NR, Beier K, Luo L, Malenka RC (2015) Diversity of transgenic mouse models for selective targeting of midbrain dopamine neurons. Neuron 85:429\u2013438. https:\/\/doi.org\/10.1016\/j.neuron.2014.12.036","journal-title":"Neuron"},{"key":"5635_CR56","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1038\/s41593-019-0567-0","volume":"23","author":"K Lee","year":"2020","unstructured":"Lee K et al (2020) Temporally restricted dopaminergic control of reward-conditioned movements. Nat Neurosci 23:209\u2013216. https:\/\/doi.org\/10.1038\/s41593-019-0567-0","journal-title":"Nat Neurosci"},{"key":"5635_CR57","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/j.cell.2015.07.014","volume":"162","author":"TN Lerner","year":"2015","unstructured":"Lerner TN, Shilyansky C, Davidson TJ, Evans KE, Beier KT, Zalocusky KA, Crow AK, Malenka RC, Luo L, Tomer R, Deisseroth K (2015) Intact-brain analyses reveal distinct information carried by SNc dopamine subcircuits. Cell 162:635\u2013647. https:\/\/doi.org\/10.1016\/j.cell.2015.07.014","journal-title":"Cell"},{"key":"5635_CR58","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1002\/syn.890170311","volume":"17","author":"CA Leslie","year":"1994","unstructured":"Leslie CA, Robertson MW, Jung AB, Liebermann J, Bennett JP Jr (1994) Effects of prenatal cocaine exposure upon postnatal development of neostriatal dopaminergic function. Synapse 17:210\u2013215. https:\/\/doi.org\/10.1002\/syn.890170311","journal-title":"Synapse"},{"key":"5635_CR59","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1038\/npp.2016.278","volume":"42","author":"MH Li","year":"2017","unstructured":"Li MH, Underhill SM, Reed C, Phillips TJ, Amara SG, Ingram SL (2017) Amphetamine and methamphetamine increase NMDAR-GluN2B synaptic currents in midbrain dopamine neurons. Neuropsychopharmacology 42:1539\u20131547. https:\/\/doi.org\/10.1038\/npp.2016.278","journal-title":"Neuropsychopharmacology"},{"key":"5635_CR60","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1002\/gene.20065","volume":"40","author":"J Lindeberg","year":"2004","unstructured":"Lindeberg J, Usoskin D, Bengtsson H, Gustafsson A, Kylberg A, Soderstrom S, Ebendal T (2004) Transgenic expression of Cre recombinase from the tyrosine hydroxylase locus. Genesis 40:67\u201373. https:\/\/doi.org\/10.1002\/gene.20065","journal-title":"Genesis"},{"key":"5635_CR61","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012141","volume":"5","author":"Y Luo","year":"2010","unstructured":"Luo Y, Good CH, Diaz-Ruiz O, Zhang YJ, Hoffman AF, Shan L, Kuang SY, Malik N, Chefer VI, Tomac AC, Lupica CR, B\u00e4ckman CM (2010) NMDA receptors on non-dopaminergic neurons in the VTA support cocaine sensitization. PLoS One 5:e12141. https:\/\/doi.org\/10.1371\/journal.pone.0012141","journal-title":"PLoS One"},{"key":"5635_CR62","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1146\/annurev-neuro-070815-013920","volume":"39","author":"C Luscher","year":"2016","unstructured":"Luscher C (2016) The emergence of a circuit model for addiction. Annu Rev Neurosci 39:257\u2013276. https:\/\/doi.org\/10.1146\/annurev-neuro-070815-013920","journal-title":"Annu Rev Neurosci"},{"key":"5635_CR63","doi-asserted-by":"publisher","first-page":"3600","DOI":"10.1523\/JNEUROSCI.3101-18.2019","volume":"39","author":"NM McCall","year":"2019","unstructured":"McCall NM, Marron Fernandez de Velasco E, Wickman K (2019) GIRK channel activity in dopamine neurons of the ventral tegmental area bidirectionally regulates behavioral sensitivity to cocaine. J Neurosci 39:3600\u20133610. https:\/\/doi.org\/10.1523\/JNEUROSCI.3101-18.2019","journal-title":"J Neurosci"},{"key":"5635_CR64","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.tins.2018.12.004","volume":"42","author":"RA McCutcheon","year":"2019","unstructured":"McCutcheon RA, Abi-Dargham A, Howes OD (2019) Schizophrenia, dopamine and the striatum: from biology to symptoms. Trends Neurosci 42:205\u2013220. https:\/\/doi.org\/10.1016\/j.tins.2018.12.004","journal-title":"Trends Neurosci"},{"key":"5635_CR65","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1038\/nrn.2016.165","volume":"18","author":"M Morales","year":"2017","unstructured":"Morales M, Margolis EB (2017) Ventral tegmental area: cellular heterogeneity, connectivity and behaviour. Nat Rev Neurosci 18:73\u201385. https:\/\/doi.org\/10.1038\/nrn.2016.165","journal-title":"Nat Rev Neurosci"},{"key":"5635_CR66","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1038\/nature11011","volume":"485","author":"BM Neale","year":"2012","unstructured":"Neale BM et al (2012) Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature 485:242\u2013245. https:\/\/doi.org\/10.1038\/nature11011","journal-title":"Nature"},{"key":"5635_CR67","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1242\/dev.144949","volume":"144","author":"N Nouri","year":"2017","unstructured":"Nouri N, Awatramani R (2017) A novel floor plate boundary defined by adjacent En1 and Dbx1 microdomains distinguishes midbrain dopamine and hypothalamic neurons. Development 144:916\u2013927. https:\/\/doi.org\/10.1242\/dev.144949","journal-title":"Development"},{"key":"5635_CR68","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/j.pbb.2012.09.020","volume":"103","author":"B O'Neill","year":"2013","unstructured":"O'Neill B, Gu HH (2013) Amphetamine-induced locomotion in a hyperdopaminergic ADHD mouse model depends on genetic background. Pharmacol Biochem Behav 103:455\u2013459. https:\/\/doi.org\/10.1016\/j.pbb.2012.09.020","journal-title":"Pharmacol Biochem Behav"},{"key":"5635_CR69","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1021\/acschemneuro.6b00300","volume":"8","author":"B O'Neill","year":"2017","unstructured":"O'Neill B, Patel JC, Rice ME (2017) Characterization of optically and electrically evoked dopamine release in striatal slices from digenic knock-in mice with DAT-driven expression of channelrhodopsin. ACS Chem Neurosci 8:310\u2013319. https:\/\/doi.org\/10.1021\/acschemneuro.6b00300","journal-title":"ACS Chem Neurosci"},{"key":"5635_CR70","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1002\/mds.27115","volume":"32","author":"JA Obeso","year":"2017","unstructured":"Obeso JA et al (2017) Past, present, and future of Parkinson\u2019s disease: a special essay on the 200th anniversary of the shaking palsy. Mov Disord 32:1264\u20131310. https:\/\/doi.org\/10.1002\/mds.27115","journal-title":"Mov Disord"},{"key":"5635_CR71","doi-asserted-by":"publisher","unstructured":"Papathanou M, Dumas S, Pettersson H, Olson L, Wallen-Mackenzie A (2019) Off-target effects in transgenic mice: characterization of dopamine transporter (DAT)-Cre transgenic mouse lines exposes multiple non-dopaminergic neuronal clusters available for selective targeting within limbic neurocircuitry. eNeuro 6. https:\/\/doi.org\/10.1523\/ENEURO.0198-19.2019","DOI":"10.1523\/ENEURO.0198-19.2019"},{"key":"5635_CR72","doi-asserted-by":"publisher","unstructured":"Patriarchi T, Cho JR, Merten K, Howe MW, Marley A, Xiong WH, Folk RW, Broussard GJ, Liang R, Jang MJ, Zhong H, Dombeck D, von Zastrow M, Nimmerjahn A, Gradinaru V, Williams JT, Tian L (2018) Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors. Science 360. https:\/\/doi.org\/10.1126\/science.aat4422","DOI":"10.1126\/science.aat4422"},{"key":"5635_CR73","doi-asserted-by":"publisher","first-page":"1818","DOI":"10.1038\/sj.npp.1300724","volume":"30","author":"VM Pogorelov","year":"2005","unstructured":"Pogorelov VM, Rodriguiz RM, Insco ML, Caron MG, Wetsel WC (2005) Novelty seeking and stereotypic activation of behavior in mice with disruption of the Dat1 gene. Neuropsychopharmacology 30:1818\u20131831. https:\/\/doi.org\/10.1038\/sj.npp.1300724","journal-title":"Neuropsychopharmacology"},{"key":"5635_CR74","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.tins.2015.04.005","volume":"38","author":"S Pupe","year":"2015","unstructured":"Pupe S, Wallen-Mackenzie A (2015) Cre-driven optogenetics in the heterogeneous genetic panorama of the VTA. Trends Neurosci 38:375\u2013386. https:\/\/doi.org\/10.1016\/j.tins.2015.04.005","journal-title":"Trends Neurosci"},{"key":"5635_CR75","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1002\/syn.21671","volume":"67","author":"A Rao","year":"2013","unstructured":"Rao A, Sorkin A, Zahniser NR (2013) Mice expressing markedly reduced striatal dopamine transporters exhibit increased locomotor activity, dopamine uptake turnover rate, and cocaine responsiveness. Synapse 67:668\u2013677. https:\/\/doi.org\/10.1002\/syn.21671","journal-title":"Synapse"},{"key":"5635_CR76","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/s0031-9384(02)00856-9","volume":"77","author":"RJ Rodgers","year":"2002","unstructured":"Rodgers RJ, Boullier E, Chatzimichalaki P, Cooper GD, Shorten A (2002) Contrasting phenotypes of C57BL\/6JOlaHsd, 129S2\/SvHsd and 129\/SvEv mice in two exploration-based tests of anxiety-related behaviour. Physiol Behav 77:301\u2013310. https:\/\/doi.org\/10.1016\/s0031-9384(02)00856-9","journal-title":"Physiol Behav"},{"key":"5635_CR77","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/j.tins.2013.03.003","volume":"36","author":"J Roeper","year":"2013","unstructured":"Roeper J (2013) Dissecting the diversity of midbrain dopamine neurons. Trends Neurosci 36:336\u2013342. https:\/\/doi.org\/10.1016\/j.tins.2013.03.003","journal-title":"Trends Neurosci"},{"key":"5635_CR78","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1111\/ejn.13347","volume":"45","author":"AH Runegaard","year":"2017","unstructured":"Runegaard AH, Jensen KL, Fitzpatrick CM, Dencker D, Weikop P, Gether U, Rickhag M (2017) Preserved dopaminergic homeostasis and dopamine-related behaviour in hemizygous TH-Cre mice. Eur J Neurosci 45:121\u2013128. https:\/\/doi.org\/10.1111\/ejn.13347","journal-title":"Eur J Neurosci"},{"key":"5635_CR79","doi-asserted-by":"publisher","unstructured":"Runegaard AH, S\u00f8rensen AT, Fitzpatrick CM, J\u00f8rgensen SH, Petersen AV, Hansen NW, Weikop P, Andreasen JT, Mikkelsen JD, Perrier JF, Woldbye D, Rickhag M, Wortwein G, Gether U (2018) Locomotor- and reward-enhancing effects of cocaine are differentially regulated by chemogenetic stimulation of gi-signaling in dopaminergic neurons. 5:eNeuro. https:\/\/doi.org\/10.1523\/ENEURO.0345-17.2018","DOI":"10.1523\/ENEURO.0345-17.2018"},{"key":"5635_CR80","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.biopsych.2006.03.020","volume":"61","author":"A Salahpour","year":"2007","unstructured":"Salahpour A, Medvedev IO, Beaulieu JM, Gainetdinov RR, Caron MG (2007) Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals. Biol Psychiatry 61:65\u201369. https:\/\/doi.org\/10.1016\/j.biopsych.2006.03.020","journal-title":"Biol Psychiatry"},{"key":"5635_CR81","doi-asserted-by":"publisher","first-page":"6721","DOI":"10.1523\/JNEUROSCI.0760-05.2005","volume":"25","author":"JM Savitt","year":"2005","unstructured":"Savitt JM, Jang SS, Mu W, Dawson VL, Dawson TM (2005) Bcl-x is required for proper development of the mouse substantia nigra. J Neurosci 25:6721\u20136728. https:\/\/doi.org\/10.1523\/JNEUROSCI.0760-05.2005","journal-title":"J Neurosci"},{"key":"5635_CR82","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1038\/nn.3185","volume":"15","author":"J Schiemann","year":"2012","unstructured":"Schiemann J et al (2012) K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration. Nat Neurosci 15:1272\u20131280. https:\/\/doi.org\/10.1038\/nn.3185","journal-title":"Nat Neurosci"},{"key":"5635_CR83","doi-asserted-by":"publisher","first-page":"13702","DOI":"10.1073\/pnas.240471297","volume":"97","author":"EE Schmidt","year":"2000","unstructured":"Schmidt EE, Taylor DS, Prigge JR, Barnett S, Capecchi MR (2000) Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids. Proc Natl Acad Sci U S A 97:13702\u201313707. https:\/\/doi.org\/10.1073\/pnas.240471297","journal-title":"Proc Natl Acad Sci U S A"},{"key":"5635_CR84","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1038\/ni0707-665","volume":"8","author":"M Schmidt-Supprian","year":"2007","unstructured":"Schmidt-Supprian M, Rajewsky K (2007) Vagaries of conditional gene targeting. Nat Immunol 8:665\u2013668. https:\/\/doi.org\/10.1038\/ni0707-665","journal-title":"Nat Immunol"},{"key":"5635_CR85","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.celrep.2016.05.067","volume":"16","author":"ME Soden","year":"2016","unstructured":"Soden ME, Miller SM, Burgeno LM, Phillips PEM, Hnasko TS, Zweifel LS (2016) Genetic isolation of hypothalamic neurons that regulate context-specific male social behavior. Cell Rep 16:304\u2013313. https:\/\/doi.org\/10.1016\/j.celrep.2016.05.067","journal-title":"Cell Rep"},{"key":"5635_CR86","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/s002130100901","volume":"159","author":"C Spielewoy","year":"2001","unstructured":"Spielewoy C, Biala G, Roubert C, Hamon M, Betancur C, Giros B (2001) Hypolocomotor effects of acute and daily d-amphetamine in mice lacking the dopamine transporter. Psychopharmacology (Berl) 159:2\u20139. https:\/\/doi.org\/10.1007\/s002130100901","journal-title":"Psychopharmacology (Berl)"},{"key":"5635_CR87","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1097\/00008877-200006000-00011","volume":"11","author":"C Spielewoy","year":"2000","unstructured":"Spielewoy C, Roubert C, Hamon M, Nosten-Bertrand M, Betancur C, Giros B (2000) Behavioural disturbances associated with hyperdopaminergia in dopamine-transporter knockout mice. Behav Pharmacol 11:279\u2013290. https:\/\/doi.org\/10.1097\/00008877-200006000-00011","journal-title":"Behav Pharmacol"},{"key":"5635_CR88","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1016\/j.neuron.2013.08.023","volume":"80","author":"AM Stamatakis","year":"2013","unstructured":"Stamatakis AM et al (2013) A unique population of ventral tegmental area neurons inhibits the lateral habenula to promote reward. Neuron 80:1039\u20131053. https:\/\/doi.org\/10.1016\/j.neuron.2013.08.023","journal-title":"Neuron"},{"key":"5635_CR89","doi-asserted-by":"publisher","first-page":"1564","DOI":"10.1016\/j.cell.2016.08.024","volume":"166","author":"WR Stauffer","year":"2016","unstructured":"Stauffer WR, Lak A, Yang A, Borel M, Paulsen O, Boyden ES, Schultz W (2016) Dopamine neuron-specific optogenetic stimulation in rhesus macaques. Cell 166:1564\u20131571 e1566. https:\/\/doi.org\/10.1016\/j.cell.2016.08.024","journal-title":"Cell"},{"key":"5635_CR90","doi-asserted-by":"publisher","unstructured":"Steinmetz NA et al (2017) Aberrant cortical activity in multiple GCaMP6-expressing transgenic mouse lines. eNeuro 4. https:\/\/doi.org\/10.1523\/ENEURO.0207-17.2017","DOI":"10.1523\/ENEURO.0207-17.2017"},{"key":"5635_CR91","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1016\/j.neuron.2014.12.034","volume":"85","author":"GD Stuber","year":"2015","unstructured":"Stuber GD, Stamatakis AM, Kantak PA (2015) Considerations when using cre-driver rodent lines for studying ventral tegmental area circuitry. Neuron 85:439\u2013445. https:\/\/doi.org\/10.1016\/j.neuron.2014.12.034","journal-title":"Neuron"},{"key":"5635_CR92","doi-asserted-by":"publisher","first-page":"4102","DOI":"10.1523\/JNEUROSCI.15-05-04102.1995","volume":"15","author":"D Sulzer","year":"1995","unstructured":"Sulzer D, Chen TK, Lau YY, Kristensen H, Rayport S, Ewing A (1995) Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport. J Neurosci 15:4102\u20134108","journal-title":"J Neurosci"},{"key":"5635_CR93","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1038\/nature19325","volume":"537","author":"T Takeuchi","year":"2016","unstructured":"Takeuchi T et al (2016) Locus coeruleus and dopaminergic consolidation of everyday memory. Nature 537:357\u2013362. https:\/\/doi.org\/10.1038\/nature19325","journal-title":"Nature"},{"key":"5635_CR94","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1002\/syn.20746","volume":"64","author":"YH Tian","year":"2010","unstructured":"Tian YH, Baek JH, Lee SY, Jang CG (2010) Prenatal and postnatal exposure to bisphenol a induces anxiolytic behaviors and cognitive deficits in mice. Synapse 64:432\u2013439. https:\/\/doi.org\/10.1002\/syn.20746","journal-title":"Synapse"},{"key":"5635_CR95","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/1471-2202-8-42","volume":"8","author":"MR Tilley","year":"2007","unstructured":"Tilley MR, Cagniard B, Zhuang X, Han DD, Tiao N, Gu HH (2007) Cocaine reward and locomotion stimulation in mice with reduced dopamine transporter expression. BMC Neurosci 8:42. https:\/\/doi.org\/10.1186\/1471-2202-8-42","journal-title":"BMC Neurosci"},{"key":"5635_CR96","doi-asserted-by":"publisher","first-page":"111","DOI":"10.3389\/fnbeh.2014.00111","volume":"8","author":"JT Ting","year":"2014","unstructured":"Ting JT, Feng G (2014) Recombineering strategies for developing next generation BAC transgenic tools for optogenetics and beyond. Front Behav Neurosci 8:111. https:\/\/doi.org\/10.3389\/fnbeh.2014.00111","journal-title":"Front Behav Neurosci"},{"key":"5635_CR97","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1038\/nature11466","volume":"490","author":"NX Tritsch","year":"2012","unstructured":"Tritsch NX, Ding JB, Sabatini BL (2012) Dopaminergic neurons inhibit striatal output through non-canonical release of GABA. Nature 490:262\u2013266. https:\/\/doi.org\/10.1038\/nature11466","journal-title":"Nature"},{"key":"5635_CR98","doi-asserted-by":"publisher","first-page":"1080","DOI":"10.1126\/science.1168878","volume":"324","author":"HC Tsai","year":"2009","unstructured":"Tsai HC, Zhang F, Adamantidis A, Stuber GD, Bonci A, de Lecea L, Deisseroth K (2009) Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science 324:1080\u20131084. https:\/\/doi.org\/10.1126\/science.1168878","journal-title":"Science"},{"key":"5635_CR99","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1016\/s0092-8674(00)81826-7","volume":"87","author":"JZ Tsien","year":"1996","unstructured":"Tsien JZ et al (1996) Subregion- and cell type-restricted gene knockout in mouse brain. Cell 87:1317\u20131326. https:\/\/doi.org\/10.1016\/s0092-8674(00)81826-7","journal-title":"Cell"},{"key":"5635_CR100","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1038\/nature11740","volume":"493","author":"KM Tye","year":"2013","unstructured":"Tye KM et al (2013) Dopamine neurons modulate neural encoding and expression of depression-related behaviour. Nature 493:537\u2013541. https:\/\/doi.org\/10.1038\/nature11740","journal-title":"Nature"},{"key":"5635_CR101","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.neuint.2018.05.012","volume":"123","author":"SM Underhill","year":"2019","unstructured":"Underhill SM, Ingram SL, Ahmari SE, Veenstra-VanderWeele J, Amara SG (2019) Neuronal excitatory amino acid transporter EAAT3: emerging functions in health and disease. Neurochem Int 123:69\u201376. https:\/\/doi.org\/10.1016\/j.neuint.2018.05.012","journal-title":"Neurochem Int"},{"key":"5635_CR102","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1016\/j.neuron.2014.05.043","volume":"83","author":"SM Underhill","year":"2014","unstructured":"Underhill SM, Wheeler DS, Li M, Watts SD, Ingram SL, Amara SG (2014) Amphetamine modulates excitatory neurotransmission through endocytosis of the glutamate transporter EAAT3 in dopamine neurons. Neuron 83:404\u2013416. https:\/\/doi.org\/10.1016\/j.neuron.2014.05.043","journal-title":"Neuron"},{"key":"5635_CR103","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1016\/j.tins.2012.02.003","volume":"35","author":"MA Ungless","year":"2012","unstructured":"Ungless MA, Grace AA (2012) Are you or aren\u2019t you? Challenges associated with physiologically identifying dopamine neurons. Trends Neurosci 35:422\u2013430. https:\/\/doi.org\/10.1016\/j.tins.2012.02.003","journal-title":"Trends Neurosci"},{"key":"5635_CR104","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.tips.2013.07.005","volume":"34","author":"RA Vaughan","year":"2013","unstructured":"Vaughan RA, Foster JD (2013) Mechanisms of dopamine transporter regulation in normal and disease states. Trends Pharmacol Sci 34:489\u2013496. https:\/\/doi.org\/10.1016\/j.tips.2013.07.005","journal-title":"Trends Pharmacol Sci"},{"key":"5635_CR105","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1046\/j.1601-183x.2003.0044.x","volume":"3","author":"V Voikar","year":"2004","unstructured":"Voikar V, Vasar E, Rauvala H (2004) Behavioral alterations induced by repeated testing in C57BL\/6J and 129S2\/Sv mice: implications for phenotyping screens. Genes Brain Behav 3:27\u201338. https:\/\/doi.org\/10.1046\/j.1601-183x.2003.0044.x","journal-title":"Genes Brain Behav"},{"key":"5635_CR106","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1001\/archpsyc.64.8.932","volume":"64","author":"ND Volkow","year":"2007","unstructured":"Volkow ND et al (2007) Depressed dopamine activity in caudate and preliminary evidence of limbic involvement in adults with attention-deficit\/hyperactivity disorder. Arch Gen Psychiatry 64:932\u2013940. https:\/\/doi.org\/10.1001\/archpsyc.64.8.932","journal-title":"Arch Gen Psychiatry"},{"key":"5635_CR107","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.neuroscience.2015.08.060","volume":"307","author":"HE Vuong","year":"2015","unstructured":"Vuong HE, Perez de Sevilla Muller L, Hardi CN, McMahon DG, Brecha NC (2015) Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines. Neuroscience 307:319\u2013337. https:\/\/doi.org\/10.1016\/j.neuroscience.2015.08.060","journal-title":"Neuroscience"},{"key":"5635_CR108","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1016\/j.neuron.2011.10.019","volume":"72","author":"LP Wang","year":"2011","unstructured":"Wang LP, Li F, Wang D, Xie K, Wang D, Shen X, Tsien JZ (2011) NMDA receptors in dopaminergic neurons are crucial for habit learning. Neuron 72:1055\u20131066. https:\/\/doi.org\/10.1016\/j.neuron.2011.10.019","journal-title":"Neuron"},{"key":"5635_CR109","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1111\/ejn.12818","volume":"41","author":"T Yamaguchi","year":"2015","unstructured":"Yamaguchi T, Qi J, Wang HL, Zhang S, Morales M (2015) Glutamatergic and dopaminergic neurons in the mouse ventral tegmental area. Eur J Neurosci 41:760\u2013772. https:\/\/doi.org\/10.1111\/ejn.12818","journal-title":"Eur J Neurosci"},{"key":"5635_CR110","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.jchemneu.2017.12.002","volume":"90","author":"SH Yip","year":"2018","unstructured":"Yip SH, York J, Hyland B, Bunn SJ, Grattan DR (2018) Incomplete concordance of dopamine transporter Cre (DAT(IREScre))-mediated recombination and tyrosine hydroxylase immunoreactivity in the mouse forebrain. J Chem Neuroanat 90:40\u201348. https:\/\/doi.org\/10.1016\/j.jchemneu.2017.12.002","journal-title":"J Chem Neuroanat"},{"key":"5635_CR111","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.jneumeth.2004.09.020","volume":"143","author":"X Zhuang","year":"2005","unstructured":"Zhuang X, Masson J, Gingrich JA, Rayport S, Hen R (2005) Targeted gene expression in dopamine and serotonin neurons of the mouse brain. J Neurosci Methods 143:27\u201332. https:\/\/doi.org\/10.1016\/j.jneumeth.2004.09.020","journal-title":"J Neurosci Methods"},{"key":"5635_CR112","doi-asserted-by":"publisher","first-page":"1982","DOI":"10.1073\/pnas.98.4.1982","volume":"98","author":"X Zhuang","year":"2001","unstructured":"Zhuang X, Oosting RS, Jones SR, Gainetdinov RR, Miller GW, Caron MG, Hen R (2001) Hyperactivity and impaired response habituation in hyperdopaminergic mice. Proc Natl Acad Sci U S A 98:1982\u20131987. https:\/\/doi.org\/10.1073\/pnas.98.4.1982","journal-title":"Proc Natl Acad Sci U S A"},{"key":"5635_CR113","doi-asserted-by":"publisher","first-page":"5719","DOI":"10.1073\/pnas.1701736114","volume":"114","author":"ID Zike","year":"2017","unstructured":"Zike ID et al (2017) OCD candidate gene SLC1A1\/EAAT3 impacts basal ganglia-mediated activity and stereotypic behavior. Proc Natl Acad Sci U S A 114:5719\u20135724. https:\/\/doi.org\/10.1073\/pnas.1701736114","journal-title":"Proc Natl Acad Sci U S A"},{"key":"5635_CR114","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/j.neuron.2008.05.028","volume":"59","author":"LS Zweifel","year":"2008","unstructured":"Zweifel LS, Argilli E, Bonci A, Palmiter RD (2008) Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors. Neuron 59:486\u2013496. https:\/\/doi.org\/10.1016\/j.neuron.2008.05.028","journal-title":"Neuron"}],"updated-by":[{"DOI":"10.1007\/s00213-020-05718-2","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T00:00:00Z","timestamp":1605657600000}}],"container-title":["Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00213-020-05635-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00213-020-05635-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00213-020-05635-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T19:38:25Z","timestamp":1628537905000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00213-020-05635-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,10]]},"references-count":114,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["5635"],"URL":"https:\/\/doi.org\/10.1007\/s00213-020-05635-4","relation":{},"ISSN":["0033-3158","1432-2072"],"issn-type":[{"value":"0033-3158","type":"print"},{"value":"1432-2072","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,10]]},"assertion":[{"value":"4 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 July 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2020","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s00213-020-05718-2","URL":"https:\/\/doi.org\/10.1007\/s00213-020-05718-2","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All animal care and testing were conducted following NIH guidelines and were approved by Institutional Animal Care and Use Committee of New York State Psychiatric Institute.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"JV has served on advisory boards for Roche, Novartis, and SynapDx. He has received research funding from Roche, Novartis, Forest, Janssen, SynapDx, and Seaside Therapeutics. He has received stipends for editorial work from Wiley and Springer. The other authors declare no biomedical conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}