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Cannabis policy conditions were \u201cUS legal\u2013recreational\u201d (legal for both recreational and medical uses), \u201cUS legal\u2013medical only\u201d, \u201cUS illegal\u201d, and \u201cCanada\u2013medical only\u201d.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The overall prevalence of self-reported ever cannabis use for medical purposes was 27%, with similar rates by sex and the highest prevalence in young adults. Prevalence was higher in US legal\u2013recreational states (34%) than US illegal states (23%), US legal\u2013medical only states (25%), and Canada (25%). The most common physical health reasons include use to manage pain (53%), sleep (46%), headaches\/migraines (35%), appetite (22%), and nausea\/vomiting (21%). For mental health reasons, the most common were for anxiety (52%), depression (40%), and PTSD\/trauma (17%). There were 11% who reported using cannabis for managing other drug or alcohol use and 4% for psychosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A substantial proportion of the North American population self-reported cannabis use for medical purposes for a variety of medical reasons, including those living in jurisdictions without legal markets. Further research is needed to understand the safety and efficacy of these forms of medical cannabis use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00213-021-06047-8","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T01:03:00Z","timestamp":1641949380000},"page":"1509-1519","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":149,"title":["Prevalence and self-reported reasons of cannabis use for medical purposes in USA and Canada"],"prefix":"10.1007","volume":"239","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5816-2959","authenticated-orcid":false,"given":"Janni","family":"Leung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Stjepanovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack Yiu Chak","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Hammond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,1,12]]},"reference":[{"issue":"12","key":"6047_CR1","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1016\/S2215-0366(19)30401-8","volume":"6","author":"N Black","year":"2019","unstructured":"Black N, Stockings E, Campbell G, Tran LT, Zagic D, Hall WD, Degenhardt L (2019) Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis. 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