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The analytic sample (<jats:italic>N<\/jats:italic>\u2009=\u20092163; 53.9% female; 43.5% Hispanic\/Latino;\u00a0baseline\u00a0<jats:italic>M<\/jats:italic> age\u2009=\u200917.1\u00a0years) included students who reported never using illicit drugs at baseline (spring, 11th grade) and provided data at follow-up (fall and spring, 12th grade). Logistic regression models assessed associations between use of smoked, vaporized, edible, concentrate, and blunt cannabis at baseline (yes\/no for each product) and any non-cannabis illicit drug use initiation\u2014including cocaine, methamphetamine, psychedelics, ecstasy, heroin, prescription opioids, or benzodiazepines\u2014at follow-up.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Among those who never used\u00a0non-cannabis illicit drugs at baseline, ever cannabis use varied by cannabis product (smoked\u2009=\u200925.8%, edible\u2009=\u200917.5%, vaporized\u2009=\u20098.4%, concentrates\u2009=\u20093.9%, and blunts\u2009=\u200918.2%) and patterns of use (single product use\u2009=\u20098.2% and poly-product\u00a0use\u2009=\u200921.8%). After adjustment for baseline covariates, odds of illicit drug use at follow-up were largest for baseline ever users of concentrates (aOR [95% CI]\u2009=\u20095.74[3.16\u201310.43]), followed by vaporized (aOR [95% CI]\u2009=\u20093.11 [2.41\u20134.01]), edibles (aOR [95% CI]\u2009=\u20093.43 [2.32\u20135.08]), blunts (aOR [95% CI]\u2009=\u20092.66[1.60\u20134.41]), and smoked (aOR [95% CI]\u2009=\u20092.57 [1.64\u20134.02]) cannabis. Ever use of a single product (aOR [95% CI]\u2009=\u20092.34 [1.26\u20134.34]) or 2\u2009+\u2009products (aOR [95% CI]\u2009=\u20093.82 [2.73\u20135.35]) were also associated with greater odds of illicit drug initiation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>For each of five different cannabis products, cannabis use was associated with greater odds of subsequent illicit drug use initiation, especially for cannabis concentrate and poly-product use.\n<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00213-023-06330-w","type":"journal-article","created":{"date-parts":[[2023,3,3]],"date-time":"2023-03-03T04:29:16Z","timestamp":1677817756000},"page":"1529-1539","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Associations of alternative cannabis product use and poly-use with subsequent illicit drug use initiation during adolescence"],"prefix":"10.1007","volume":"242","author":[{"given":"Jessica L.","family":"Braymiller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kira E.","family":"Riehm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeline","family":"Meier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan A.","family":"Krueger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer B.","family":"Unger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica L.","family":"Barrington-Trimis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhan","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. 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