{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:09:46Z","timestamp":1791299386491,"version":"4.1.0"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T00:00:00Z","timestamp":1708473600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T00:00:00Z","timestamp":1708473600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Psychopharmacology"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1007\/s00213-023-06507-3","type":"journal-article","created":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T19:02:31Z","timestamp":1708542151000},"page":"753-766","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Synergistic antidepressant-like effect of citicoline and CB 1 agonist in male mice"],"prefix":"10.1007","volume":"241","author":[{"given":"Aysan","family":"Amanzade","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Khakpai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0688-5378","authenticated-orcid":false,"given":"Mohammad-Reza","family":"Zarrindast","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,21]]},"reference":[{"key":"6507_CR1","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1046\/j.0022-3042.2001.00697.x","volume":"80","author":"RM Adibhatla","year":"2002","unstructured":"Adibhatla RM, Hatcher JF, Dempsey RJ (2002) Citicoline: neuroprotective mechanisms in cerebral ischemia. J Neurochem 80:12\u201323","journal-title":"J Neurochem"},{"key":"6507_CR2","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1111\/j.1749-6632.2000.tb06944.x","volume":"920","author":"J Agut","year":"2000","unstructured":"Agut J, Ortiz JA, Wurtman RJ (2000) Cytidine (5')diphosphocholine modulates dopamine K(+)-evoked release in striatum measured by microdialysis. Ann N Y Acad Sci 920:332\u2013335","journal-title":"Ann N Y Acad Sci"},{"key":"6507_CR3","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1016\/j.biopha.2018.10.033","volume":"109","author":"S Alijanpour","year":"2019","unstructured":"Alijanpour S, Khakpai F, Ebrahimi-Ghiri M, Zarrindast MR (2019) Co-administration of the low dose of orexin and nitrergic antagonists induces an antidepressant-like effect in mice. Biomed Pharmacother 109:589\u2013594","journal-title":"Biomed Pharmacother"},{"key":"6507_CR4","doi-asserted-by":"publisher","first-page":"S123","DOI":"10.1016\/j.pmrj.2011.03.012","volume":"3","author":"PM Arenth","year":"2011","unstructured":"Arenth PM, Russell KC, Ricker JH, Zafonte RD (2011) CDP-choline as a biological supplement during neurorecovery: a focused review. PM R 3:S123\u2013S131","journal-title":"PM R"},{"key":"6507_CR5","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1111\/j.1600-0447.2011.01687.x","volume":"124","author":"C Ashton","year":"2011","unstructured":"Ashton C, Moore P (2011) Endocannabinoid system dysfunction in mood and related disorders. Acta Psychiatr Scand 124:250\u2013261","journal-title":"Acta Psychiatr Scand"},{"key":"6507_CR6","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1007\/s00213-002-1045-y","volume":"161","author":"S Babb","year":"2002","unstructured":"Babb S, Wald L, Cohen B, Villafuerte R, Gruber S, Yurgelun-Todd D, Renshaw P (2002) Chronic citicoline increases phosphodiesters in the brains of healthy older subjects: an in vivo phosphorus magnetic resonance spectroscopy study. Psychopharmacology 161:248\u2013254","journal-title":"Psychopharmacology"},{"key":"6507_CR7","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-59745-387-5","volume-title":"Handbook of clinical rating scales and assessment in psychiatry and mental health","author":"L Baer","year":"2010","unstructured":"Baer L, Blais MA (2010) Handbook of clinical rating scales and assessment in psychiatry and mental health. Springer"},{"key":"6507_CR8","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.physbeh.2014.06.003","volume":"135","author":"A Bahi","year":"2014","unstructured":"Bahi A, Al Mansouri S, Al Memari E, Al Ameri M, Nurulain SM, Ojha S (2014) \u03b2-Caryophyllene, a CB2 receptor agonist produces multiple behavioral changes relevant to anxiety and depression in mice. Physiol Behav 135:119\u2013124","journal-title":"Physiol Behav"},{"key":"6507_CR9","doi-asserted-by":"publisher","first-page":"5526","DOI":"10.3390\/ijms23105526","volume":"23","author":"U Bright","year":"2022","unstructured":"Bright U, Akirav I (2022) Modulation of endocannabinoid system components in depression: pre-clinical and clinical evidence. Int J Mol Sci 23:5526","journal-title":"Int J Mol Sci"},{"key":"6507_CR10","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.jad.2012.05.006","volume":"143","author":"ES Brown","year":"2012","unstructured":"Brown ES, Gabrielson B (2012) A randomized, double-blind, placebo-controlled trial of citicoline for bipolar and unipolar depression and methamphetamine dependence. J Affect Disord 143:257\u2013260","journal-title":"J Affect Disord"},{"key":"6507_CR11","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.pnpbp.2018.01.026","volume":"84","author":"O Burstein","year":"2018","unstructured":"Burstein O, Shoshan N, Doron R, Akirav I (2018) Cannabinoids prevent depressive-like symptoms and alterations in BDNF expression in a rat model of PTSD. Prog Neuropsychopharmacol Biol Psychiatry 84:129\u2013139","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"6507_CR12","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.pnpbp.2012.05.018","volume":"39","author":"S Chiba","year":"2012","unstructured":"Chiba S, Numakawa T, Ninomiya M, Richards MC, Wakabayashi C, Kunugi H (2012) Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex. Prog Neuropsychopharmacol Biol Psychiatry 39:112\u2013119","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"6507_CR13","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.bbr.2010.08.044","volume":"216","author":"SH Christiansen","year":"2011","unstructured":"Christiansen SH, Olesen MV, Wortwein G, Woldbye DP (2011) Fluoxetine reverts chronic restraint stress-induced depression-like behaviour and increases neuropeptide Y and galanin expression in mice. Behav Brain Res 216:585\u2013591","journal-title":"Behav Brain Res"},{"key":"6507_CR14","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1038\/nrn1683","volume":"6","author":"ER de Kloet","year":"2005","unstructured":"de Kloet ER, Joels M, Holsboer F (2005) Stress and the brain: from adaptation to disease. Nat Rev Neurosci 6:463\u2013475","journal-title":"Nat Rev Neurosci"},{"key":"6507_CR15","doi-asserted-by":"publisher","first-page":"287","DOI":"10.2147\/JPR.S70481","volume":"9","author":"DR Emril","year":"2016","unstructured":"Emril DR, Wibowo S, Meliala L, Susilowati R (2016) Cytidine 5'-diphosphocholine administration prevents peripheral neuropathic pain after sciatic nerve crush injury in rats. J Pain Res 9:287\u2013291","journal-title":"J Pain Res"},{"key":"6507_CR16","doi-asserted-by":"publisher","first-page":"247","DOI":"10.2147\/ciia.2006.1.3.247","volume":"1","author":"M Fioravanti","year":"2006","unstructured":"Fioravanti M, Buckley AE (2006) Citicoline (Cognizin) in the treatment of cognitive impairment. Clin Interv Aging 1:247\u2013251","journal-title":"Clin Interv Aging"},{"key":"6507_CR17","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.762738","volume":"12","author":"I Gallego-Landin","year":"2021","unstructured":"Gallego-Landin I, Garcia-Baos A, Castro-Zavala A, Valverde O (2021) Reviewing the role of the endocannabinoid system in the pathophysiology of depression. Front Pharmacol 12:762738","journal-title":"Front Pharmacol"},{"key":"6507_CR18","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.jns.2010.08.027","volume":"299","author":"R Garcia-Cobos","year":"2010","unstructured":"Garcia-Cobos R, Frank-Garcia A, Gutierrez-Fernandez M, Diez-Tejedor E (2010) Citicoline, use in cognitive decline: vascular and degenerative. J Neurol Sci 299:188\u2013192","journal-title":"J Neurol Sci"},{"key":"6507_CR19","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.bbr.2014.03.047","volume":"268","author":"JA Grizzell","year":"2014","unstructured":"Grizzell JA, Iarkov A, Holmes R, Mori T, Echeverria V (2014) Cotinine reduces depressive-like behavior, working memory deficits, and synaptic loss associated with chronic stress in mice. Behav Brain Res 268:55\u201365","journal-title":"Behav Brain Res"},{"key":"6507_CR20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158950","volume":"11","author":"T Hayase","year":"2016","unstructured":"Hayase T (2016) Putative epigenetic involvement of the endocannabinoid system in anxiety-and depression-related behaviors caused by nicotine as a stressor. PLoS One 11:e0158950","journal-title":"PLoS One"},{"key":"6507_CR21","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1590\/S0100-879X2012007500041","volume":"45","author":"JP Herman","year":"2012","unstructured":"Herman JP, McKlveen JM, Solomon MB, Carvalho-Netto E, Myers B (2012) Neural regulation of the stress response: glucocorticoid feedback mechanisms. Braz J Med Biol Res 45:292\u2013298","journal-title":"Braz J Med Biol Res"},{"key":"6507_CR22","doi-asserted-by":"publisher","first-page":"2899","DOI":"10.3892\/mmr.2016.5585","volume":"14","author":"WJ Huang","year":"2016","unstructured":"Huang WJ, Chen WW, Zhang X (2016) Endocannabinoid system: role in depression, reward and pain control (Review). Mol Med Rep 14:2899\u20132903","journal-title":"Mol Med Rep"},{"key":"6507_CR23","doi-asserted-by":"publisher","first-page":"108717","DOI":"10.1016\/j.biopha.2019.108717","volume":"112","author":"F Khakpai","year":"2019","unstructured":"Khakpai F, Ebrahimi-Ghiri M, Alijanpour S, Zarrindast M-R (2019) Ketamine-induced antidepressant like effects in mice: a possible involvement of cannabinoid system. Biomed Pharmacother 112:108717","journal-title":"Biomed Pharmacother"},{"key":"6507_CR24","doi-asserted-by":"publisher","first-page":"136095","DOI":"10.1016\/j.neulet.2021.136095","volume":"760","author":"F Khakpai","year":"2021","unstructured":"Khakpai F, Ramezanikhah M, Valizadegan F, Zarrindast M-R (2021) Synergistic effect between imipramine and citicoline upon induction of analgesic and antidepressant effects in mice. Neurosci Lett 760:136095","journal-title":"Neurosci Lett"},{"key":"6507_CR25","doi-asserted-by":"crossref","first-page":"194","DOI":"10.55782\/ane-2023-017","volume":"83","author":"F Khakpai","year":"2023","unstructured":"Khakpai F, Zarrindast MR (2023) The effect of nicotine on antidepressant and anxiolytic responses induced by citalopram and citicoline in mice. Acta Neurobiol Exp 83:194\u2013202","journal-title":"Acta Neurobiol Exp"},{"key":"6507_CR26","doi-asserted-by":"publisher","first-page":"2709","DOI":"10.1038\/npp.2014.132","volume":"39","author":"N Korem","year":"2014","unstructured":"Korem N, Akirav I (2014) Cannabinoids prevent the effects of a footshock followed by situational reminders on emotional processing. Neuropsychopharmacology 39:2709\u20132722","journal-title":"Neuropsychopharmacology"},{"key":"6507_CR27","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.bbr.2015.01.051","volume":"284","author":"M Kruk-Slomka","year":"2015","unstructured":"Kruk-Slomka M, Michalak A, Biala G (2015) Antidepressant-like effects of the cannabinoid receptor ligands in the forced swimming test in mice: mechanism of action and possible interactions with cholinergic system. Behav Brain Res 284:24\u201336","journal-title":"Behav Brain Res"},{"key":"6507_CR28","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.bbr.2011.10.007","volume":"227","author":"S Li","year":"2012","unstructured":"Li S, Fan YX, Wang W, Tang YY (2012) Effects of acute restraint stress on different components of memory as assessed by object-recognition and object-location tasks in mice. Behav Brain Res 227:199\u2013207","journal-title":"Behav Brain Res"},{"key":"6507_CR29","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1097\/ADM.0b013e3181d80c93","volume":"5","author":"SC Licata","year":"2011","unstructured":"Licata SC, Penetar DM, Ravichandran C, Rodolico J, Palmer C, Berko J, Geaghan T, Looby A, Peters E, Ryan E (2011) Effects of daily treatment with citicoline: a double-blind, placebo-controlled study in cocaine-dependent volunteers. J Addict Med 5:57","journal-title":"J Addict Med"},{"key":"6507_CR30","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.pharmthera.2012.12.002","volume":"138","author":"V Micale","year":"2013","unstructured":"Micale V, Di Marzo V, Sulcova A, Wotjak CT, Drago F (2013) Endocannabinoid system and mood disorders: priming a target for new therapies. Pharmacol Ther 138:18\u201337","journal-title":"Pharmacol Ther"},{"key":"6507_CR31","first-page":"1","volume":"(Berl)","author":"S Mosaffa","year":"2020","unstructured":"Mosaffa S, Ahmadi H, Khakpai F, Ebrahimi-Ghiri M, Zarrindast MR (2020) Synergistic antidepressant- and anxiolytic-like effects of harmaline along with cinanserin in acute restraint stress-treated mice. Psychopharmacology (Berl):1\u201311","journal-title":"Psychopharmacology"},{"key":"6507_CR32","doi-asserted-by":"publisher","first-page":"146701","DOI":"10.1016\/j.brainres.2020.146701","volume":"1734","author":"S Nejati","year":"2020","unstructured":"Nejati S, Khakpai F, Zarrindast MR (2020) Synergistic effect between citalopram and citicoline on anxiolytic effect in non-sensitized and morphine-sensitized mice: an isobologram analysis. Brain Res 1734:146701","journal-title":"Brain Res"},{"key":"6507_CR33","volume-title":"The mouse brain in stereotaxic coordinates","author":"G Paxinos","year":"2001","unstructured":"Paxinos G, Franklin KBJ (2001) The mouse brain in stereotaxic coordinates, 2nd edn. Academic Press, San Diego","edition":"2"},{"key":"6507_CR34","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.lfs.2018.09.058","volume":"213","author":"E Poleszak","year":"2018","unstructured":"Poleszak E, Wosko S, Slawinska K, Szopa A, Wrobel A, Serefko A (2018) Cannabinoids in depressive disorders. Life Sci 213:18\u201324","journal-title":"Life Sci"},{"key":"6507_CR35","doi-asserted-by":"publisher","first-page":"3738","DOI":"10.2174\/13816128113196660740","volume":"20","author":"P R Albert","year":"2014","unstructured":"R Albert P, M Fiori L (2014) Transcriptional dys-regulation in anxiety and major depression: 5-HT1A gene promoter architecture as a therapeutic opportunity. Curr Pharm Design 20:3738\u20133750","journal-title":"Curr Pharm Design"},{"key":"6507_CR36","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.physbeh.2018.08.002","volume":"195","author":"M Roohi-Azizi","year":"2018","unstructured":"Roohi-Azizi M, Torkaman-Boutorabi A, Akhondzadeh S, Nejatisafa AA, Sadat-Shirazi MS, Zarrindast MR (2018) Influence of citicoline on citalopram-induced antidepressant activity in depressive-like symptoms in male mice. Physiol Behav 195:151\u2013157","journal-title":"Physiol Behav"},{"key":"6507_CR37","doi-asserted-by":"publisher","first-page":"173449","DOI":"10.1016\/j.pbb.2022.173449","volume":"219","author":"N Saadati","year":"2022","unstructured":"Saadati N, Bananej M, Khakpai F, Zarrindast M-R, Alibeik H (2022) Synergistic antidepressant effects of citalopram and SB-334867 in the REM sleep-deprived mice: possible role of BDNF. Pharmacol Biochem Behav 219:173449","journal-title":"Pharmacol Biochem Behav"},{"key":"6507_CR38","doi-asserted-by":"publisher","first-page":"2557","DOI":"10.1073\/pnas.1416866112","volume":"112","author":"BD Sachs","year":"2015","unstructured":"Sachs BD, Ni JR, Caron MG (2015) Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress. Proc Natl Acad Sci 112:2557\u20132562","journal-title":"Proc Natl Acad Sci"},{"key":"6507_CR39","doi-asserted-by":"publisher","first-page":"81","DOI":"10.9758\/cpn.2020.18.1.81","volume":"18","author":"M Safavi","year":"2020","unstructured":"Safavi M, Hosseini-Sharifabad A, Seyed-Yousefi Y, Rabbani M (2020) Protective effects of citicoline and benfotiamine each alone and in combination on streptozotocin-induced memory impairment in mice. Clin Psychopharmacol Neurosci 18:81\u201392","journal-title":"Clin Psychopharmacol Neurosci"},{"key":"6507_CR40","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/1745-0179-3-25","volume":"3","author":"G Serra","year":"2007","unstructured":"Serra G, Fratta W (2007) A possible role for the endocannabinoid system in the neurobiology of depression. Clin Pract Epidemiol Ment Health 3:25","journal-title":"Clin Pract Epidemiol Ment Health"},{"key":"6507_CR41","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1002\/npr2.12093","volume":"40","author":"H Shoji","year":"2020","unstructured":"Shoji H, Miyakawa T (2020) Differential effects of stress exposure via two types of restraint apparatuses on behavior and plasma corticosterone level in inbred male BALB\/cAJcl mice. Neuropsychopharmacol Rep 40:73\u201384","journal-title":"Neuropsychopharmacol Rep"},{"key":"6507_CR42","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1002\/nbm.1281","volume":"21","author":"M Silveri","year":"2008","unstructured":"Silveri M, Dikan J, Ross A, Jensen J, Kamiya T, Kawada Y, Renshaw P, Yurgelun-Todd D (2008) Citicoline enhances frontal lobe bioenergetics as measured by phosphorus magnetic resonance spectroscopy. NMR Biomed: Int J Devoted Dev Appl Magn Resonance In vivo 21:1066\u20131075","journal-title":"NMR Biomed: Int J Devoted Dev Appl Magn Resonance In vivo"},{"key":"6507_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4103\/0974-8490.171100","volume":"8","author":"K Sulakhiya","year":"2016","unstructured":"Sulakhiya K, Patel VK, Saxena R, Dashore J, Srivastava AK, Rathore M (2016) Effect of Beta vulgaris Linn. leaves extract on anxiety- and depressive-like behavior and oxidative stress in mice after acute restraint stress. Pharmacognosy Res 8:1\u20137","journal-title":"Pharmacognosy Res"},{"key":"6507_CR44","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/j.pbb.2008.05.010","volume":"90","author":"I Svizenska","year":"2008","unstructured":"Svizenska I, Dubovy P, Sulcova A (2008) Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures--a short review. Pharmacol Biochem Behav 90:501\u2013511","journal-title":"Pharmacol Biochem Behav"},{"key":"6507_CR45","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.bbr.2015.05.006","volume":"291","author":"V Vargas-Lopez","year":"2015","unstructured":"Vargas-Lopez V, Torres-Berrio A, Gonzalez-Martinez L, Munera A, Lamprea MR (2015) Acute restraint stress and corticosterone transiently disrupts novelty preference in an object recognition task. Behav Brain Res 291:60\u201366","journal-title":"Behav Brain Res"},{"key":"6507_CR46","doi-asserted-by":"publisher","first-page":"e58488","DOI":"10.1371\/journal.pone.0058488","volume":"8","author":"JL Voorhees","year":"2013","unstructured":"Voorhees JL, Tarr AJ, Wohleb ES, Godbout JP, Mo X, Sheridan JF, Eubank TD, Marsh CB (2013) Prolonged restraint stress increases IL-6, reduces IL-10, and causes persistent depressive-like behavior that is reversed by recombinant IL-10. PLoS One 8:e58488","journal-title":"PLoS One"},{"key":"6507_CR47","doi-asserted-by":"publisher","first-page":"262","DOI":"10.3109\/00952990.2014.925467","volume":"40","author":"ND Wignall","year":"2014","unstructured":"Wignall ND, Brown ES (2014) Citicoline in addictive disorders: a review of the literature. Am J Drug Alcohol Abuse 40:262\u2013268","journal-title":"Am J Drug Alcohol Abuse"},{"key":"6507_CR48","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/j.tips.2005.10.006","volume":"26","author":"JM Witkin","year":"2005","unstructured":"Witkin JM, Tzavara ET, Davis RJ, Li X, Nomikos GG (2005) A therapeutic role for cannabinoid CB1 receptor antagonists in major depressive disorders. Trends Pharmacol Sci 26:609\u2013617","journal-title":"Trends Pharmacol Sci"},{"key":"6507_CR49","doi-asserted-by":"crossref","first-page":"154","DOI":"10.55782\/ane-2023-014","volume":"83","author":"MR Zarrindast","year":"2023","unstructured":"Zarrindast MR, Khakpai F (2023) A synergistic analgesic effect of morphine in combination with the CB1 receptor agonist, ACPA, in normal, hypothyroid, and hyperthyroid male rats. Acta Neurobiol Exp (Wars) 83:154\u2013170","journal-title":"Acta Neurobiol Exp (Wars)"},{"key":"6507_CR50","unstructured":"Zhou D, Li Y, Tian T, Quan W, Wang L, Shao Q, Fu L-Q, Zhang X-H, Wang X-Y, Zhang H (2017a) Role of the endocannabinoid system in the formation and development of depression. Die Pharmazie-An International Journal of Pharmaceutical Sciences 72:435\u2013439"},{"key":"6507_CR51","unstructured":"Zhou D, Li Y, Tian T, Quan W, Wang L, Shao Q, Fu LQ, Zhang XH, Wang XY, Zhang H, Ma YM (2017b) Role of the endocannabinoid system in the formation and development of depression. Pharmazie 72:435\u2013439"}],"container-title":["Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00213-023-06507-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00213-023-06507-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00213-023-06507-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T04:31:39Z","timestamp":1731385899000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00213-023-06507-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,21]]},"references-count":51,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["6507"],"URL":"https:\/\/doi.org\/10.1007\/s00213-023-06507-3","relation":{},"ISSN":["0033-3158","1432-2072"],"issn-type":[{"value":"0033-3158","type":"print"},{"value":"1432-2072","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,21]]},"assertion":[{"value":"8 July 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 November 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 February 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}