{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T10:32:00Z","timestamp":1785148320143,"version":"3.55.0"},"reference-count":57,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:00:00Z","timestamp":1716854400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:00:00Z","timestamp":1716854400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100008899","name":"University of South Carolina","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100008899","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Psychopharmacology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Rationale<\/jats:title>\n                <jats:p>Stress during childhood or adolescence increases vulnerability to psychiatric disorders in adults. In adult rodents, the delayed effects of stress can increase anxiety-like behavior. These effects, however, can be prevented with post-stress administration of corticosterone (CORT). The effectiveness of CORT in preventing adolescent stress-induced emotional behavior alterations in adulthood has yet to be investigated.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Objectives<\/jats:title>\n                <jats:p>Here, we investigated the interactions between early adolescent stress and exogenous corticosterone on adult social, aversive, and drug-seeking behavior in mice, which are translationally related to symptoms associated with psychiatric and substance abuse disorders.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods and results<\/jats:title>\n                <jats:p>A single administration of CORT in drinking water (400ug\/mL) for 24\u00a0h after social defeat or context fear conditioning prevents defeat-induced social avoidance, alters fear processing, prevents adolescent stress-induced anhedonia, and prevents stress-potentiated morphine place preference in adulthood. Exogenous CORT did not immediately prevent stress-induced potentiation of morphine conditioned-place preference in adolescents but did so in adult mice. However, when administered to adolescent mice, CORT also prevented the incubation of morphine-conditioned place preference into adulthood. Lastly, exogenous CORT administration blunted endogenous corticosterone but was unrelated to freezing behavior during a fear test.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This is the first demonstration of adolescent post-stress CORT promoting socio-emotional resilience and preventing drug-seeking behavior. Our data suggest elevated corticosterone after a stress experience promotes resilience for at least 40 days across the developmental transition from adolescence to adulthood and is effective for socio-emotional and drug-seeking behavior. These results are critical for understanding how adolescent stress impacts emotional and drug-seeking behavior into adulthood.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00213-024-06616-7","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T05:01:45Z","timestamp":1716872505000},"page":"2045-2059","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Corticosterone after early adolescent stress prevents social avoidance, aversive behavior, and morphine-conditioned place preference in adulthood"],"prefix":"10.1007","volume":"241","author":[{"given":"Samantha O.","family":"Vanderhoof","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carly J.","family":"Vincent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmin N.","family":"Beaver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maeson S.","family":"Latsko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Aguilar-Alvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4015-4202","authenticated-orcid":false,"given":"Aaron M.","family":"Jasnow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,28]]},"reference":[{"key":"6616_CR1","doi-asserted-by":"publisher","first-page":"1488","DOI":"10.1176\/appi.ajp.161.8.1488","volume":"161","author":"A Aerni","year":"2004","unstructured":"Aerni A, Traber R, Hock C, Roozendaal B, Schelling G, Papassotiropoulos A, Nitsch RM, Schnyder U, de Quervain DJ (2004) Low-dose cortisol for symptoms of posttraumatic stress disorder. Am J Psychiatry 161:1488\u20131490","journal-title":"Am J Psychiatry"},{"key":"6616_CR2","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1038\/s41398-022-02118-2","volume":"12","author":"KA Albernaz-Mariano","year":"2022","unstructured":"Albernaz-Mariano KA, Demarchi Munhoz C (2022) The infralimbic mineralocorticoid blockage prevents the stress-induced impairment of aversive memory extinction in rats. Transl Psychiatry 12:343","journal-title":"Transl Psychiatry"},{"key":"6616_CR3","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1007\/s002130000569","volume":"153","author":"MT Bardo","year":"2000","unstructured":"Bardo MT, Bevins RA (2000) Conditioned place preference: what does it add to our preclinical understanding of drug reward? Psychopharmacology 153:31\u201343","journal-title":"Psychopharmacology"},{"key":"6616_CR4","doi-asserted-by":"publisher","first-page":"2139","DOI":"10.1038\/s41386-020-0758-0","volume":"45","author":"P Chakraborty","year":"2020","unstructured":"Chakraborty P, Datta S, McEwen BS, Chattarji S (2020) Corticosterone after acute stress prevents the delayed effects on the amygdala. Neuropsychopharmacology 45:2139\u20132146","journal-title":"Neuropsychopharmacology"},{"key":"6616_CR5","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/j.jad.2003.12.013","volume":"82","author":"DP Chapman","year":"2004","unstructured":"Chapman DP, Whitfield CL, Felitti VJ, Dube SR, Edwards VJ, Anda RF (2004) Adverse childhood experiences and the risk of depressive disorders in adulthood. J Affect Disord 82:217\u2013225","journal-title":"J Affect Disord"},{"key":"6616_CR6","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.nlm.2004.01.002","volume":"81","author":"CD Conrad","year":"2004","unstructured":"Conrad CD, MacMillan DD 2nd, Tsekhanov S, Wright RL, Baran SE, Fuchs RA (2004) Influence of chronic corticosterone and glucocorticoid receptor antagonism in the amygdala on fear conditioning. Neurobiol Learn Mem 81:185\u2013199","journal-title":"Neurobiol Learn Mem"},{"key":"6616_CR7","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1101\/lm.032961.113","volume":"21","author":"PK Cullen","year":"2014","unstructured":"Cullen PK, Dulka BN, Ortiz S, Riccio DC, Jasnow AM (2014) GABA-mediated presynaptic inhibition is required for precision of long-term memory. Learn Mem 21:180\u2013184","journal-title":"Learn Mem"},{"key":"6616_CR8","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.nlm.2015.07.001","volume":"124","author":"PK Cullen","year":"2015","unstructured":"Cullen PK, Gilman TL, Winiecki P, Riccio DC, Jasnow AM (2015) Activity of the anterior cingulate cortex and ventral hippocampus underlie increases in contextual fear generalization. Neurobiol Learn Mem 124:19\u201327","journal-title":"Neurobiol Learn Mem"},{"key":"6616_CR9","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1017\/S1092852913000096","volume":"18","author":"DL Delahanty","year":"2013","unstructured":"Delahanty DL, Gabert-Quillen C, Ostrowski SA, Nugent NR, Fischer B, Morris A, Pitman RK, Bon J, Fallon W (2013) The efficacy of initial hydrocortisone administration at preventing posttraumatic distress in adult trauma patients: a randomized trial. CNS Spectr 18:103\u2013111","journal-title":"CNS Spectr"},{"key":"6616_CR10","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1002\/hipo.20216","volume":"16","author":"Z Dong","year":"2006","unstructured":"Dong Z, Han H, Wang M, Xu L, Hao W, Cao J (2006) Morphine conditioned place preference depends on glucocorticoid receptors in both hippocampus and nucleus accumbens. Hippocampus 16:809\u2013813","journal-title":"Hippocampus"},{"key":"6616_CR11","doi-asserted-by":"publisher","first-page":"3089","DOI":"10.1001\/jama.286.24.3089","volume":"286","author":"SR Dube","year":"2001","unstructured":"Dube SR, Anda RF, Felitti VJ, Chapman DP, Williamson DF, Giles WH (2001) Childhood abuse, household dysfunction, and the risk of attempted suicide throughout the life span: findings from the adverse childhood experiences Study. JAMA 286:3089\u20133096","journal-title":"JAMA"},{"key":"6616_CR12","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/S0749-3797(98)00017-8","volume":"14","author":"VJ Felitti","year":"1998","unstructured":"Felitti VJ, Anda RF, Nordenberg D, Williamson DF, Spitz AM, Edwards V, Koss MP, Marks JS (1998) Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The adverse childhood experiences (ACE) study. Am J Prev Med 14:245\u2013258","journal-title":"Am J Prev Med"},{"key":"6616_CR13","doi-asserted-by":"crossref","unstructured":"Galatzer-Levy IR, Bonanno GA, Bush DEA, LeDoux JE (2013) Heterogeneity in threat extinction learning: substantive and methodological considerations for identifying individual difference in response to stress. Front Behav Neurosci 7","DOI":"10.3389\/fnbeh.2013.00055"},{"key":"6616_CR14","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1176\/appi.ajp.161.8.1417","volume":"161","author":"GL Gladstone","year":"2004","unstructured":"Gladstone GL, Parker GB, Mitchell PB, Malhi GS, Wilhelm K, Austin MP (2004) Implications of childhood trauma for depressed women: an analysis of pathways from childhood sexual abuse to deliberate self-harm and revictimization. Am J Psychiatry 161:1417\u20131425","journal-title":"Am J Psychiatry"},{"key":"6616_CR15","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1176\/ajp.153.7.929","volume":"153","author":"AK Goenjian","year":"1996","unstructured":"Goenjian AK, Yehuda R, Pynoos RS, Steinberg AM, Tashjian M, Yang RK, Najarian LM, Fairbanks LA (1996) Basal cortisol, dexamethasone suppression of cortisol, and MHPG in adolescents after the 1988 earthquake in Armenia. Am J Psychiatry 153:929\u2013934","journal-title":"Am J Psychiatry"},{"key":"6616_CR16","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1159\/000122169","volume":"12","author":"L Goldman","year":"1973","unstructured":"Goldman L, Winget C, Hollingshead GW, Levine S (1973) Postweaning Development of negative feedback in the pituitary-adrenal system of the rat. Neuroendocrinology 12:199\u2013211","journal-title":"Neuroendocrinology"},{"key":"6616_CR17","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.tics.2013.01.001","volume":"17","author":"O Hardt","year":"2013","unstructured":"Hardt O, Nader K, Nadel L (2013) Decay happens: the role of active forgetting in memory. Trends Cogn Sci 17:111\u2013120","journal-title":"Trends Cogn Sci"},{"key":"6616_CR18","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1176\/appi.ajp.158.4.575","volume":"158","author":"C Heim","year":"2001","unstructured":"Heim C, Newport DJ, Bonsall R, Miller AH, Nemeroff CB (2001) Altered pituitary-adrenal axis responses to provocative challenge tests in adult survivors of childhood abuse. Am J Psychiatry 158:575\u2013581","journal-title":"Am J Psychiatry"},{"key":"6616_CR19","doi-asserted-by":"publisher","first-page":"e15","DOI":"10.1016\/j.biopsych.2013.04.021","volume":"74","author":"K Hinkelmann","year":"2013","unstructured":"Hinkelmann K, Muhtz C, Dettenborn L, Agorastos A, Wingenfeld K, Spitzer C, Gao W, Kirschbaum C, Wiedemann K, Otte C (2013) Association between childhood trauma and low hair cortisol in depressed patients and healthy control subjects. Biol Psychiatry 74:e15\u2013e17","journal-title":"Biol Psychiatry"},{"key":"6616_CR20","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.nlm.2014.02.001","volume":"112","author":"B Hruska","year":"2014","unstructured":"Hruska B, Cullen PK, Delahanty DL (2014) Pharmacological modulation of acute trauma memories to prevent PTSD: considerations from a developmental perspective. Neurobiol Learn Mem 112:122\u2013129","journal-title":"Neurobiol Learn Mem"},{"key":"6616_CR21","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.nlm.2003.09.002","volume":"81","author":"G Hui","year":"2004","unstructured":"Hui G, Figueroa I, Poytress B, Roozendaal B, McGaugh J, Weinberger N (2004) Memory enhancement of classical fear conditioning by post-training injections of corticosterone in rats. Neurobiol Learn Mem 81:67\u201374","journal-title":"Neurobiol Learn Mem"},{"key":"6616_CR22","unstructured":"Jasnow A, Ressler K (2006) Interpersonal Violence as a Mediator of Stress-Related Disorders in Humans. Birkhauser"},{"key":"6616_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fpsyg.2012.00175","volume":"3","author":"AM Jasnow","year":"2012","unstructured":"Jasnow AM, Cullen PK, Riccio DC (2012) Remembering another aspect of forgetting. Front Psychol 3:1\u20138","journal-title":"Front Psychol"},{"key":"6616_CR24","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1002\/jnr.23837","volume":"95","author":"AM Jasnow","year":"2017","unstructured":"Jasnow AM, Lynch JF 3rd, Gilman TL, Riccio DC (2017) Perspectives on fear generalization and its implications for emotional disorders. J Neurosci Res 95:821\u2013835","journal-title":"J Neurosci Res"},{"key":"6616_CR25","doi-asserted-by":"crossref","unstructured":"Jimeno B, Verhulst S (2023) Meta-analysis reveals glucocorticoid levels reflect variation in metabolic rate, not \u2018stress\u2019. Elife 12","DOI":"10.7554\/eLife.88205"},{"key":"6616_CR26","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1192\/bjp.bp.110.080499","volume":"197","author":"RC Kessler","year":"2010","unstructured":"Kessler RC, McLaughlin KA, Green JG, Gruber MJ, Sampson NA, Zaslavsky AM, Aguilar-Gaxiola S, Alhamzawi AO, Alonso J, Angermeyer M, Benjet C, Bromet E, Chatterji S, de Girolamo G, Demyttenaere K, Fayyad J, Florescu S, Gal G, Gureje O, Haro JM, Hu CY, Karam EG, Kawakami N, Lee S, Lepine JP, Ormel J, Posada-Villa J, Sagar R, Tsang A, Ustun TB, Vassilev S, Viana MC, Williams DR (2010) Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys. Br J Psychiatry 197:378\u2013385","journal-title":"Br J Psychiatry"},{"key":"6616_CR27","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1046\/j.1440-1819.2001.00787.x","volume":"55","author":"JA King","year":"2001","unstructured":"King JA, Mandansky D, King S, Fletcher KE, Brewer J (2001) Early sexual abuse and low cortisol. Psychiatry Clin Neurosci 55:71\u201374","journal-title":"Psychiatry Clin Neurosci"},{"key":"6616_CR28","first-page":"170","volume-title":"Corticosterone treatment provides protection into adulthood from the adverse effects of adolescent social defeat","author":"MS Latsko","year":"2018","unstructured":"Latsko MS (2018) Corticosterone treatment provides protection into adulthood from the adverse effects of adolescent social defeat. Psychology. Kent State University, Kent, Ohio, p 170"},{"key":"6616_CR29","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.yhbeh.2016.04.009","volume":"82","author":"MS Latsko","year":"2016","unstructured":"Latsko MS, Farnbauch LA, Gilman TL, Lynch JF 3rd, Jasnow AM (2016) Corticosterone may interact with peripubertal development to shape adult resistance to social defeat. Horm Behav 82:38\u201345","journal-title":"Horm Behav"},{"key":"6616_CR30","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.physbeh.2012.06.011","volume":"107","author":"P Lui","year":"2012","unstructured":"Lui P, Padow VA, Franco D, Hall BS, Park B, Klein ZA, Romeo RD (2012) Divergent stress-induced neuroendocrine and behavioral responses prior to puberty. Physiol Behav 107:104\u2013111","journal-title":"Physiol Behav"},{"key":"6616_CR31","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1038\/npp.2016.255","volume":"42","author":"JF Lynch","year":"2017","unstructured":"Lynch JF, Winiecki P, Gilman TL, Adkins JM, Jasnow AM (2017) Hippocampal GABA(B(1a)) receptors constrain generalized contextual fear. Neuropsychopharmacology 42:914\u2013924","journal-title":"Neuropsychopharmacology"},{"key":"6616_CR32","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/S0006-8993(98)00882-8","volume":"809","author":"AM Magarinos","year":"1998","unstructured":"Magarinos AM, Orchinik M, McEwen BS (1998) Morphological changes in the hippocampal CA3 region induced by non-invasive glucocorticoid administration: a paradox. Brain Res 809:314\u2013318","journal-title":"Brain Res"},{"key":"6616_CR33","doi-asserted-by":"publisher","first-page":"1362","DOI":"10.1001\/jama.1997.03540410040028","volume":"277","author":"J McCauley","year":"1997","unstructured":"McCauley J, Kern DE, Kolodner K et al (1997) Clinical characteristics of women with a history of childhood abuse: unhealed wounds. JAMA 277:1362\u20131368","journal-title":"JAMA"},{"key":"6616_CR34","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1038\/sj.mp.4001939","volume":"12","author":"K Myers","year":"2006","unstructured":"Myers K, Davis M (2006) Mechanisms of fear extinction. Mol Psychiatry 12:120\u2013150","journal-title":"Mol Psychiatry"},{"key":"6616_CR35","doi-asserted-by":"publisher","first-page":"6526","DOI":"10.1523\/JNEUROSCI.0810-19.2019","volume":"39","author":"S Ortiz","year":"2019","unstructured":"Ortiz S, Latsko MS, Fouty JL, Dutta S, Adkins JM, Jasnow AM (2019) Anterior Cingulate Cortex and ventral hippocampal inputs to the Basolateral Amygdala selectively Control Generalized Fear. J Neurosci 39:6526\u20136539","journal-title":"J Neurosci"},{"key":"6616_CR36","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1016\/j.biopsych.2012.04.008","volume":"72","author":"RP Rao","year":"2012","unstructured":"Rao RP, Anilkumar S, McEwen BS, Chattarji S (2012) Glucocorticoids protect against the delayed behavioral and cellular effects of acute stress on the amygdala. Biol Psychiatry 72:466\u2013475","journal-title":"Biol Psychiatry"},{"key":"6616_CR37","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1007\/s00213-006-0345-z","volume":"185","author":"B Ribeiro Do Couto","year":"2006","unstructured":"Ribeiro Do Couto B, Aguilar MA, Manzanedo C, Rodr\u00edguez-Arias M, Armario A, Mi\u00f1arro J (2006) Social stress is as effective as physical stress in reinstating morphine-induced place preference in mice. Psychopharmacology 185:459\u2013470","journal-title":"Psychopharmacology"},{"key":"6616_CR38","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1111\/j.1365-2826.2003.01106.x","volume":"15","author":"R Romeo","year":"2003","unstructured":"Romeo R (2003) Puberty: a period of both organizational and activational effects of steroid hormones on neurobehavioural development. J Neuroendocrinol 15:1185\u20131192","journal-title":"J Neuroendocrinol"},{"key":"6616_CR40","doi-asserted-by":"publisher","first-page":"1664","DOI":"10.1210\/en.2005-1432","volume":"147","author":"RD Romeo","year":"2006","unstructured":"Romeo RD, Bellani R, Karatsoreos IN, Chhua N, Vernov M, Conrad CD, McEwen BS (2006) Stress history and pubertal development interact to shape hypothalamic-pituitary-adrenal axis plasticity. Endocrinology 147:1664\u20131674","journal-title":"Endocrinology"},{"key":"6616_CR41","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1159\/000102950","volume":"85","author":"RD Romeo","year":"2007","unstructured":"Romeo RD, Karatsoreos IN, Jasnow AM, McEwen BS (2007) Age- and stress-induced changes in corticotropin-releasing hormone mRNA expression in the paraventricular nucleus of the hypothalamus. Neuroendocrinology 85:199\u2013206","journal-title":"Neuroendocrinology"},{"key":"6616_CR39","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1159\/000109710","volume":"87","author":"RD Romeo","year":"2008","unstructured":"Romeo RD, Ali FS, Karatsoreos IN, Bellani R, Chhua N, Vernov M, McEwen BS (2008) Glucocorticoid receptor mRNA expression in the hippocampal formation of male rats before and after pubertal development in response to acute or repeated stress. Neuroendocrinology 87:160\u2013167","journal-title":"Neuroendocrinology"},{"key":"6616_CR42","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.psyneuen.2014.01.016","volume":"42","author":"RD Romeo","year":"2014","unstructured":"Romeo RD, Minhas S, Svirsky SE, Hall BS, Savenkova M, Karatsoreos IN (2014) Pubertal shifts in adrenal responsiveness to stress and adrenocorticotropic hormone in male rats. Psychoneuroendocrinology 42:146\u2013152","journal-title":"Psychoneuroendocrinology"},{"key":"6616_CR43","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.neubiorev.2016.05.020","volume":"70","author":"RD Romeo","year":"2016","unstructured":"Romeo RD, Patel R, Pham L, So VM (2016) Adolescence and the ontogeny of the hormonal stress response in male and female rats and mice. Neurosci Biobehav Rev 70:206\u2013216","journal-title":"Neurosci Biobehav Rev"},{"key":"6616_CR44","doi-asserted-by":"publisher","first-page":"8161","DOI":"10.1523\/JNEUROSCI.2574-04.2004","volume":"24","author":"B Roozendaal","year":"2004","unstructured":"Roozendaal B, Hahn E, Nathan S, de Quervain D, McGaugh J (2004) Glucocorticoid effects on Memory Retrieval Require Concurrent Noradrenergic Activity in the Hippocampus and Basolateral Amygdala. J Neurosci 24:8161\u20138169","journal-title":"J Neurosci"},{"key":"6616_CR45","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1038\/npp.2015.210","volume":"41","author":"T Sawamura","year":"2016","unstructured":"Sawamura T, Klengel T, Armario A, Jovanovic T, Norrholm SD, Ressler KJ, Andero R (2016) Dexamethasone Treatment leads to enhanced fear extinction and dynamic Fkbp5 regulation in Amygdala. Neuropsychopharmacology 41:832\u2013846","journal-title":"Neuropsychopharmacology"},{"key":"6616_CR46","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1016\/S0006-3223(01)01270-7","volume":"50","author":"G Schelling","year":"2001","unstructured":"Schelling G, Briegel J, Roozendaal B, Stoll C, Rothenhausler HB, Kapfhammer HP (2001) The effect of stress doses of Hydrocortisone during septic shock on posttraumatic stress disorder in survivors. Biol Psychiatry 50:978\u2013985","journal-title":"Biol Psychiatry"},{"key":"6616_CR47","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1016\/j.biopsych.2003.09.014","volume":"55","author":"G Schelling","year":"2004","unstructured":"Schelling G, Kilger E, Roozendaal B, de Quervain DJ, Briegel J, Dagge A, Rothenhausler HB, Krauseneck T, Nollert G, Kapfhammer HP (2004) Stress doses of hydrocortisone, traumatic memories, and symptoms of posttraumatic stress disorder in patients after cardiac surgery: a randomized study. Biol Psychiatry 55:627\u2013633","journal-title":"Biol Psychiatry"},{"key":"6616_CR48","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/S0149-7634(00)00014-2","volume":"24","author":"LP Spear","year":"2000","unstructured":"Spear LP (2000) The adolescent brain and age-related behavioral manifestations. Neurosci Biobehav Rev 24:417\u2013463","journal-title":"Neurosci Biobehav Rev"},{"key":"6616_CR49","first-page":"274","volume":"22","author":"A Suris","year":"2010","unstructured":"Suris A, North C, Adinoff B, Powell CM, Greene R (2010) Effects of exogenous glucocorticoid on combat-related PTSD symptoms. Ann Clin Psychiatry 22:274\u2013279","journal-title":"Ann Clin Psychiatry"},{"key":"6616_CR50","doi-asserted-by":"publisher","first-page":"107271","DOI":"10.1016\/j.nlm.2020.107271","volume":"173","author":"N Tzakis","year":"2020","unstructured":"Tzakis N, Bosnic T, Holahan MR (2020) Hippocampal and anterior cingulate cortex contribution to the processing of recently-acquired and remotely stored spatial memories in rats trained during preadolescence. Neurobiol Learn Mem 173:107271","journal-title":"Neurobiol Learn Mem"},{"key":"6616_CR51","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1111\/j.1369-1600.2007.00070.x","volume":"12","author":"TM Tzschentke","year":"2007","unstructured":"Tzschentke TM (2007) Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade. Addict Biol 12:227\u2013462","journal-title":"Addict Biol"},{"key":"6616_CR52","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1002\/dev.21839","volume":"61","author":"DM Wang","year":"2019","unstructured":"Wang DM, Zhang JJ, Huang YB, Zhao YZ, Sui N (2019) Peripubertal stress of male, but not female rats increases morphine-induced conditioned place preference and locomotion in adulthood. Dev Psychobiol 61:920\u2013929","journal-title":"Dev Psychobiol"},{"key":"6616_CR53","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1101\/lm.430907","volume":"14","author":"BJ Wiltgen","year":"2007","unstructured":"Wiltgen BJ, Silva AJ (2007) Memory for context becomes less specific with time. Learn Mem 14:313\u2013317","journal-title":"Learn Mem"},{"key":"6616_CR55","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.neuron.2007.09.006","volume":"56","author":"R Yehuda","year":"2007","unstructured":"Yehuda R, LeDoux J (2007) Response variation following trauma: a translational neuroscience approach to understanding PTSD. Neuron 56:19\u201332","journal-title":"Neuron"},{"key":"6616_CR54","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1017\/S0954579401003170","volume":"13","author":"R Yehuda","year":"2001","unstructured":"Yehuda R, Halligan SL, Grossman R (2001) Childhood trauma and risk for PTSD: relationship to intergenerational effects of trauma, parental PTSD, and cortisol excretion. Dev Psychopathol 13:733\u2013753","journal-title":"Dev Psychopathol"},{"key":"6616_CR56","doi-asserted-by":"publisher","first-page":"20140048","DOI":"10.1098\/rsfs.2014.0048","volume":"4","author":"R Yehuda","year":"2014","unstructured":"Yehuda R, Pratchett LC, Elmes MW, Lehrner A, Daskalakis NP, Koch E, Makotkine I, Flory JD, Bierer LM (2014) Glucocorticoid-related predictors and correlates of post-traumatic stress disorder treatment response in combat veterans. Interface Focus 4:20140048","journal-title":"Interface Focus"},{"key":"6616_CR57","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1006\/lmot.1996.0023","volume":"27","author":"Y Zhou","year":"1996","unstructured":"Zhou Y, Riccio D (1996) Manipulation of components of Context: the Context Shift Effect and forgetting of stimulus attributes. Learn Motiv 27:400\u2013407","journal-title":"Learn Motiv"}],"container-title":["Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00213-024-06616-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00213-024-06616-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00213-024-06616-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T06:04:39Z","timestamp":1727676279000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00213-024-06616-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,28]]},"references-count":57,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["6616"],"URL":"https:\/\/doi.org\/10.1007\/s00213-024-06616-7","relation":{},"ISSN":["0033-3158","1432-2072"],"issn-type":[{"value":"0033-3158","type":"print"},{"value":"1432-2072","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,28]]},"assertion":[{"value":"8 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors report no biomedical financial interests or potential conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}