{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T12:53:48Z","timestamp":1760014428245},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,6,6]],"date-time":"2012-06-06T00:00:00Z","timestamp":1338940800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal Bioanal Chem"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1007\/s00216-012-6108-2","type":"journal-article","created":{"date-parts":[[2012,7,14]],"date-time":"2012-07-14T07:39:03Z","timestamp":1342251543000},"page":"147-155","source":"Crossref","is-referenced-by-count":13,"title":["A new method for quantifying prenatal exposure to ethanol by microwave-assisted extraction (MAE) of meconium followed by gas chromatography\u2013mass spectrometry (GC\u2013MS)"],"prefix":"10.1007","volume":"404","author":[{"given":"Pamela","family":"Cabarcos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Jes\u00fas","family":"Tabernero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iv\u00e1n","family":"\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Miguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Purificaci\u00f3n","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Mar\u00eda","family":"Bermejo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,6,6]]},"reference":[{"key":"6108_CR1","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1067\/S0022-3476(03)00442-6","volume":"143","author":"CF Bearer","year":"2003","unstructured":"Bearer CF, Jacobson JL, Jacobson SW, Barr D, Croxford J, Molteno CD, Viljoen DL, Marais AS, Chiodo LM, Cwik AS (2003) Validation of a new biomarker of fetal exposure to alcohol. J Pediatr 143:463\u2013469","journal-title":"J Pediatr"},{"key":"6108_CR2","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1002\/jssc.201000118","volume":"33","author":"M Roehsig","year":"2010","unstructured":"Roehsig M, Mendes de Louzada D, Moura S, Albuquerque EM, Yonamine M (2010) Determination of eight fatty acid ethyl esters in meconium samples by headspace solid phase microextraction and gas chromatography\u2013mass spectrometry. J Sep Sci 33:2115\u20132122","journal-title":"J Sep Sci"},{"key":"6108_CR3","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1093\/anatox\/35.4.232","volume":"35","author":"F Gonz\u00e1lez-Ill\u00e1n","year":"2011","unstructured":"Gonz\u00e1lez-Ill\u00e1n F, Ojeda G, D\u00edaz Liz M, Rosario O (2011) Detection of fatty acid ethyl esters in skin surface lipids as biomarkers of etanol consumption in alcoholics, social drinkers, light drinkers and teetotalers using a methodology base don microwave-assisted extraction followed by solid-phase microextraction as gas chromatography\u2013mass spectrometry. J Anal Toxicol 35:232\u2013237","journal-title":"J Anal Toxicol"},{"key":"6108_CR4","doi-asserted-by":"crossref","unstructured":"Joya X, Friguls B (2012). Determination of maternal-fetal biomarkers of prenatal exposure to ethanol: A review. Journal of Pharmaceutical and Biomedical Analysis. In press","DOI":"10.1016\/j.jpba.2012.01.006"},{"key":"6108_CR5","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1007\/s00216-010-3474-5","volume":"396","author":"A Bakdash","year":"2010","unstructured":"Bakdash A, Burger P, Goecke T, Fasching P, Reulbach U, Bleich S, Hastedt M, Rothe M, Beckmann M, Pragst F, Kornhuber J (2010) Quantification of fatty acid ethyl esters (FAEE) and ethyl glucuronide (EtG) in meconium from newborns for detection of alcohol abuse in a maternal health evaluation study. Anal Bioanal Chem 396:2469\u20132477","journal-title":"Anal Bioanal Chem"},{"issue":"3","key":"6108_CR6","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/j.1530-0277.2011.01647.x","volume":"36","author":"S Pichini","year":"2011","unstructured":"Pichini S, Marchei E, Vagnarelli F, Tarani L, Raimondi F, Maffucci R, Sacher B, Bisceglia M, Rapisardi G, Elicio MR, Biban P, Zuccaro P, Pacifici R, Pierantozzi A, Morini L (2011) Assessment of prenatal exposure to ethanol by meconium analysis: Results of an Italian multicenter study. Alcohol Clin Exp Res 36(3):417\u2013424","journal-title":"Alcohol Clin Exp Res"},{"key":"6108_CR7","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.alcohol.2009.08.008","volume":"44","author":"S Shor","year":"2010","unstructured":"Shor S, Nulman I, Kulaga V, Koren G (2010) Heavy in utero ethanol exposure is associated with the use of other drugs of abuse in a high-risk population. Alcohol 44:623\u2013627","journal-title":"Alcohol"},{"key":"6108_CR8","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.alcohol.2010.02.008","volume":"44","author":"Y Goh","year":"2010","unstructured":"Goh Y, Hutson J, Lum L, Roukema H, Gareri J, Lynn H, Koren G (2010) Rates of fetal alcohol exposure among newborns in a high-risk obstetric unit. Alcohol 44:629\u2013634","journal-title":"Alcohol"},{"issue":"2","key":"6108_CR9","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1097\/FTD.0b013e318167cfe5","volume":"30","author":"J Gareri","year":"2008","unstructured":"Gareri J, Lynn H, Handley M, Rao C, Koren G (2008) Prevalence of fetal ethanol exposure in a regional population based sample by meconium analysis of fatty acid ethyl esters. Ther Drug Monit 30(2):239\u2013245","journal-title":"Ther Drug Monit"},{"key":"6108_CR10","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/00007691-200306000-00004","volume":"25","author":"D Chan","year":"2003","unstructured":"Chan D, Bar-Oz B, Pellerin B, Paciorek C, Klein J, Kapur B, Farine D, Koren G (2003) Population baseline of meconium fatty acid ethyl esters among infants of nondrinking women in Jerusalem and Toronto. Ther Drug Monit 25:271\u2013278","journal-title":"Ther Drug Monit"},{"key":"6108_CR11","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.alcohol.2010.07.005","volume":"45","author":"J Hutson","year":"2011","unstructured":"Hutson J, Rao C, Fulga N, Aleksa K, Koren G (2011) An improved method for rapidly quantifying fatty acid ethyl esters in meconium suitable for prenatal alcohol screening. Alcohol 45:193\u2013199","journal-title":"Alcohol"},{"key":"6108_CR12","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jchromb.2008.10.056","volume":"877","author":"JR Hutson","year":"2009","unstructured":"Hutson JR, Aleksa K, Pragst F, Koren G (2009) Detection and quantification of fatty acid ethyl esters in meconium by headspace solid phase microextraction and gas chromatography\u2013mass spectrometry. J Chromatogr B 877:8\u201312","journal-title":"J Chromatogr B"},{"issue":"2","key":"6108_CR13","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/FTD.0b013e31816a8657","volume":"30","author":"O Garc\u00eda-Algar","year":"2008","unstructured":"Garc\u00eda-Algar O, Kulaga V, Gareri J, Koren G, Vall O, Zuccaro P, Pacifici R, Pichini S (2008) Alarming prevalence of fetal alcohol exposure in a Mediterranean city. Ther Drug Monit 30(2):249\u2013254","journal-title":"Ther Drug Monit"},{"key":"6108_CR14","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.jpba.2008.07.026","volume":"48","author":"S Pichini","year":"2008","unstructured":"Pichini S, Pellegrini M, Gareri J, Koren G, Garc\u00eda-Algar O, Vall O, Vagnarelli F, Zuccaro P, Marchei E (2008) Liquid chromatography\u2013tandem mass spectrometry for fatty acid ethyl esters in meconium: Assessment of prenatal exposure to alcohol in two European cohorts. J Pharm Biomed Anal 48:927\u2013933","journal-title":"J Pharm Biomed Anal"},{"key":"6108_CR15","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1016\/j.jchromb.2010.05.001","volume":"878","author":"H Kwak","year":"2010","unstructured":"Kwak H, Kang Y, Han K, Moon J, Chung Y, Choi J, Han J, Kim M, Armenta E, Ocampo A (2010) Quantitation of fatty acid ethyl esters in human meconium by an improved liquid chromatography\/tandem mass spectrometry. J Chrom B 878:1871\u20131874","journal-title":"J Chrom B"},{"issue":"1","key":"6108_CR16","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1373\/49.1.133","volume":"49","author":"C Moore","year":"2003","unstructured":"Moore C, Jones J, Lewis D, Buchi K (2003) Prevalence of fatty acid ethyl esters in meconium specimens. Clin Chem 49(1):133\u2013136","journal-title":"Clin Chem"},{"key":"6108_CR17","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1007\/s00216-008-2546-2","volume":"393","author":"I \u00c1lvarez","year":"2009","unstructured":"\u00c1lvarez I, Bermejo AM, Tabernero MJ, Fern\u00e1ndez P, Cabarcos P, L\u00f3pez P (2009) Microwave-assisted extraction: a simpler and faster method for the determination of ethyl glucuronide in hair by gas chromatography\u2013mass spectrometry. Anal Bioanal Chem 393:1345\u20131350","journal-title":"Anal Bioanal Chem"},{"key":"6108_CR18","doi-asserted-by":"crossref","first-page":"2962","DOI":"10.1080\/00032710903276547","volume":"42","author":"P Cabarcos","year":"2009","unstructured":"Cabarcos P, \u00c1lvarez I, Bermejo AM, Tabernero MJ, L\u00f3pez P, Fern\u00e1ndez P (2009) Analysis of fatty acid ethyl esters in hair by headspace solid phase microextraction (HS-SPME) and gas chromatography\u2013mass spectrometry (GC\u2013MS). Anal Lett 42:2962\u20132977","journal-title":"Anal Lett"},{"key":"6108_CR19","first-page":"76","volume":"121","author":"F Pragst","year":"2001","unstructured":"Pragst F, Auw\u00e4rter V, Sporkert F, Spiegel K (2001) Analysis of fatty acid ethyl esters in hair as possible markers of chronically elevated alcohol consumption by headspace solid-phase microextraction (HS-SPME) and gas chromatography\u2013mass spectrometry (GC\u2013MS). For Sci Int 121:76\u201388","journal-title":"For Sci Int"},{"issue":"1","key":"6108_CR20","first-page":"7","volume":"1","author":"V Mandal","year":"2007","unstructured":"Mandal V, Mohan Y, Hemalatha S (2007) Micrawave assisted extraction- An innovative and promising extraction tool for medical plant research. Phcog Rev 1(1):7\u201318","journal-title":"Phcog Rev"},{"key":"6108_CR21","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/s00216-010-3572-4","volume":"397","author":"P Fern\u00e1ndez","year":"2010","unstructured":"Fern\u00e1ndez P, V\u00e1zquez C, Lorenzo RA, Carro AM, \u00c1lvarez I, Cabarcos P (2010) Experimental design for optimization of microwave-assisted extraction of benzodiazepines in human plasma. Anal Bioanal Chem 397:677\u2013685","journal-title":"Anal Bioanal Chem"},{"key":"6108_CR22","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1002\/jat.1338","volume":"28","author":"I \u00c1lvarez","year":"2008","unstructured":"\u00c1lvarez I, Bermejo AM, Cid P, Tabernero MJ, Fern\u00e1ndez P, L\u00f3pez P (2008) Microwave-assisted extraction for the determination of ethyl glucuronide in urine by gas chromatography\u2013mass spectrometry. J Appl Toxicol 28:773\u2013778","journal-title":"J Appl Toxicol"},{"key":"6108_CR23","unstructured":"Food and Drug Administration. 2001. U.S. Department of Health and Human Services, Guidance for Industry, Bioanalytical Method Validation. FDA [Available on line at URL: http:\/\/www.fda.gov\/downloads\/Drugs\/GuidanceComplianceRegulatoryInformation\/Guidances\/ucm070107.pdf ] (Accessed January 2012)"},{"key":"6108_CR24","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0378-4347(95)00387-8","volume":"675","author":"TG Bernhardt","year":"1996","unstructured":"Bernhardt TG, Cannistraro PA, Bird DA, Doyle KM, Laposata M (1996) Purification of fatty acid ethyl esters by solid phase extraction and high performance liquid chromatography. J Chromatogr B Biomed Appl 675:189\u2013196","journal-title":"J Chromatogr B Biomed Appl"},{"key":"6108_CR25","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s00216-011-4685-0","volume":"400","author":"J Gareri","year":"2011","unstructured":"Gareri J, Appenzeller B, Walasek P (2011) Impact of hair-care products on FAEE hair concentrations in substance abuse monitoring. Anal Bioanal Chem 400:183\u2013188","journal-title":"Anal Bioanal Chem"},{"key":"6108_CR26","unstructured":"Suesse S, Pragst F, Mieczkowski T, Selavka CM, Elian A, Sachs H, Hastedt M, Rothe M, Campbell J (2011). Practical experiences in application of hair fatty acid ethyl esters and ethyl glucuronide for detection of chronic alcohol abuse in forensic cases. Forensic Sci Int. In press"},{"key":"6108_CR27","first-page":"101","volume":"196","author":"F Pragst","year":"2010","unstructured":"Pragst F, Rothe M, Moench B, Hastedt M, Herre S, Simmert D (2010) Combined use of fatty acid ethyl esters and ethyl glucuronide in hair for diagnosis of alcohol abuse: Interpretation and advantages. For Sci Int 196:101\u2013110","journal-title":"For Sci Int"},{"issue":"1","key":"6108_CR28","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s00216-010-4443-8","volume":"400","author":"M Albermann","year":"2010","unstructured":"Albermann M, Musshoff F, Madea B (2010) Comparison of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) concentrations in hair for testing abstinence. Anal Bioanal Chem 400(1):175\u2013181","journal-title":"Anal Bioanal Chem"},{"key":"6108_CR29","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1002\/bdra.20464","volume":"82","author":"L Burd","year":"2008","unstructured":"Burd L, Hofer R (2008) Biomarkers for detection of prenatal alcohol exposure: A critical review of fatty acid ethyl esters in meconium. Birth Defect Res (Part A) 82:487\u2013493","journal-title":"Birth Defect Res (Part A)"}],"container-title":["Analytical and Bioanalytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-012-6108-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00216-012-6108-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-012-6108-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T20:48:28Z","timestamp":1558644508000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00216-012-6108-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,6]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["6108"],"URL":"https:\/\/doi.org\/10.1007\/s00216-012-6108-2","relation":{},"ISSN":["1618-2642","1618-2650"],"issn-type":[{"value":"1618-2642","type":"print"},{"value":"1618-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,6]]}}}