{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T11:19:40Z","timestamp":1780571980762,"version":"3.54.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2015,12,16]],"date-time":"2015-12-16T00:00:00Z","timestamp":1450224000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anal Bioanal Chem"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1007\/s00216-015-9234-9","type":"journal-article","created":{"date-parts":[[2015,12,16]],"date-time":"2015-12-16T10:51:48Z","timestamp":1450263108000},"page":"1249-1258","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Development of CT-guided biopsy sampling for time-dependent postmortem redistribution investigations in blood and alternative matrices\u2014proof of concept and application on two cases"],"prefix":"10.1007","volume":"408","author":[{"given":"Sandra N.","family":"Staeheli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominic","family":"Gascho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juergen","family":"Fornaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Laberke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars C.","family":"Ebert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa Maria","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Thali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Kraemer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea E.","family":"Steuer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,12,16]]},"reference":[{"issue":"8","key":"9234_CR1","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1093\/jat\/27.8.533","volume":"27","author":"AL Pelissier-Alicot","year":"2003","unstructured":"Pelissier-Alicot AL, Gaulier JM, Champsaur P, Marquet P. Mechanisms underlying postmortem redistribution of drugs: a review. J Anal Toxicol. 2003;27(8):533\u201344.","journal-title":"J Anal Toxicol"},{"issue":"4","key":"9234_CR2","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1007\/s12024-010-9150-4","volume":"6","author":"G Skopp","year":"2010","unstructured":"Skopp G. Postmortem toxicology. Forensic Sci Med Pathol. 2010;6(4):314\u201325.","journal-title":"Forensic Sci Med Pathol"},{"issue":"4","key":"9234_CR3","first-page":"235","volume":"43","author":"MC Yarema","year":"2005","unstructured":"Yarema MC, Becker CE. Key concepts in postmortem drug redistribution. Clintoxicol. 2005;43(4):235\u201341.","journal-title":"Clintoxicol"},{"issue":"2","key":"9234_CR4","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1520\/JFS12828J","volume":"35","author":"RW Prouty","year":"1990","unstructured":"Prouty RW, Anderson WH. The forensic science implications of site and temporal influences on postmortem blood-drug concentrations. J Forensic Sci. 1990;35(2):243\u201370.","journal-title":"J Forensic Sci"},{"issue":"6","key":"9234_CR5","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1520\/JFS14027J","volume":"41","author":"DJ Pounder","year":"1996","unstructured":"Pounder DJ, Adams E, Fuke C, Langford AM. Site to site variability of postmortem drug concentrations in liver and lung. J Forensic Sci. 1996;41(6):927\u201332.","journal-title":"J Forensic Sci"},{"issue":"1","key":"9234_CR6","first-page":"47","volume":"41","author":"JB Leikin","year":"2003","unstructured":"Leikin JB, Watson WA. Post-mortem toxicology: what the dead can and cannot tell us. J ToxicolClin Toxicol. 2003;41(1):47\u201356.","journal-title":"J ToxicolClin Toxicol"},{"issue":"1","key":"9234_CR7","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1520\/JFS14404J","volume":"44","author":"T Hilberg","year":"1999","unstructured":"Hilberg T, Rogde S, Morland J. Postmortem drug redistribution\u2014human cases related to results in experimental animals. J Forensic Sci. 1999;44(1):3\u20139.","journal-title":"J Forensic Sci"},{"issue":"1\u20133","key":"9234_CR8","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.forsciint.2012.01.016","volume":"219","author":"E Han","year":"2012","unstructured":"Han E, Kim E, Hong H, Jeong S, Kim J, In S, et al. Evaluation of postmortem redistribution phenomena for commonly encountered drugs. Forensic Sci Int. 2012;219(1\u20133):265\u201371.","journal-title":"Forensic Sci Int"},{"issue":"5","key":"9234_CR9","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1093\/jat\/11.5.186","volume":"11","author":"GR Jones","year":"1987","unstructured":"Jones GR, Pounder DJ. Site dependence of drug concentrations in postmortem blood\u2014a case study. J Anal Toxicol. 1987;11(5):186\u201390.","journal-title":"J Anal Toxicol"},{"issue":"1\u20133","key":"9234_CR10","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.forsciint.2012.05.028","volume":"222","author":"E Saar","year":"2012","unstructured":"Saar E, Beyer J, Gerostamoulos D, Drummer OH. The time-dependant post-mortem redistribution of antipsychotic drugs. Forensic Sci Int. 2012;222(1\u20133):223\u20137.","journal-title":"Forensic Sci Int"},{"issue":"4","key":"9234_CR11","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/s12024-012-9341-2","volume":"8","author":"D Gerostamoulos","year":"2012","unstructured":"Gerostamoulos D, Beyer J, Staikos V, Tayler P, Woodford N, Drummer OH. The effect of the postmortem interval on the redistribution of drugs: a comparison of mortuary admission and autopsy blood specimens. Forensic Sci Med Pathol. 2012;8(4):373\u20139.","journal-title":"Forensic Sci Med Pathol"},{"issue":"1","key":"9234_CR12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1520\/JFS16082J","volume":"43","author":"MD Robertson","year":"1998","unstructured":"Robertson MD, Drummer OH. Postmortem distribution and redistribution of nitrobenzodiazepines in man. J Forensic Sci. 1998;43(1):9\u201313.","journal-title":"J Forensic Sci"},{"issue":"2","key":"9234_CR13","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0379-0738(92)90180-5","volume":"56","author":"A Martin","year":"1992","unstructured":"Martin A, Pounder DJ. Post-mortem toxico-kinetics of trazodone. Forensic Sci Int. 1992;56(2):201\u20137.","journal-title":"Forensic Sci Int"},{"issue":"2","key":"9234_CR14","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0379-0738(93)90157-6","volume":"59","author":"K Yonemitsu","year":"1993","unstructured":"Yonemitsu K, Pounder DJ. Postmortem changes in blood tranylcypromine concentration: competing redistribution and degradation effects. Forensic Sci Int. 1993;59(2):177\u201384.","journal-title":"Forensic Sci Int"},{"issue":"4","key":"9234_CR15","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1520\/JFS14781J","volume":"45","author":"D Gerostamoulos","year":"2000","unstructured":"Gerostamoulos D, Drummer OH. Postmortem redistribution of morphine and its metabolites. J Forensic Sci. 2000;45(4):843\u20135.","journal-title":"J Forensic Sci"},{"issue":"2","key":"9234_CR16","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/PAF.0000000000000044","volume":"35","author":"VM Hargrove","year":"2014","unstructured":"Hargrove VM, Molina DK. Peripheral postmortem redistribution of morphine. Am J Forensic Med Pathol. 2014;35(2):106\u20138.","journal-title":"Am J Forensic Med Pathol"},{"issue":"1","key":"9234_CR17","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1093\/jat\/21.1.23","volume":"21","author":"BK Logan","year":"1997","unstructured":"Logan BK, Smirnow D, Gullberg RG. Lack of predictable site-dependent differences and time-dependent changes in postmortem concentrations of cocaine, benzoylecgonine, and cocaethylene in humans. J Anal Toxicol. 1997;21(1):23\u201331.","journal-title":"J Anal Toxicol"},{"issue":"2","key":"9234_CR18","first-page":"221","volume":"41","author":"BK Logan","year":"1996","unstructured":"Logan BK, Smirnow D. Postmortem distribution and redistribution of morphine in man. J Forensic Sci. 1996;41(2):221\u20139.","journal-title":"J Forensic Sci"},{"issue":"5","key":"9234_CR19","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1520\/JFS13716J","volume":"39","author":"G Quatrehomme","year":"1994","unstructured":"Quatrehomme G, Bourret F, Liao Z, Ollier A. An experimental methodology for the study of postmortem changes in toxic concentrations of drugs, using secobarbital as an example. J Forensic Sci. 1994;39(5):1300\u20134.","journal-title":"J Forensic Sci"},{"issue":"6","key":"9234_CR20","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s00414-009-0403-2","volume":"124","author":"B Brunet","year":"2010","unstructured":"Brunet B, Hauet T, Hebrard W, Papet Y, Mauco G, Mura P. Postmortem redistribution of THC in the pig. Int J Legal Med. 2010;124(6):543\u20139.","journal-title":"Int J Legal Med"},{"issue":"1","key":"9234_CR21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s12024-009-9130-8","volume":"6","author":"DM Butzbach","year":"2010","unstructured":"Butzbach DM. The influence of putrefaction and sample storage on post-mortem toxicology results. Forensic Sci Med Pathol. 2010;6(1):35\u201345.","journal-title":"Forensic Sci Med Pathol"},{"issue":"2\u20133","key":"9234_CR22","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.forsciint.2004.02.012","volume":"142","author":"G Skopp","year":"2004","unstructured":"Skopp G. Preanalytic aspects in postmortem toxicology. Forensic Sci Int. 2004;142(2\u20133):75\u2013100.","journal-title":"Forensic Sci Int"},{"issue":"3","key":"9234_CR23","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1111\/1556-4029.12389","volume":"59","author":"FL Cantrell","year":"2014","unstructured":"Cantrell FL, Ogera P, Mallett P, McIntyre IM. Fatal oral methylphenidate intoxication with postmortem concentrations. J Forensic Sci. 2014;59(3):847\u20139.","journal-title":"J Forensic Sci"},{"issue":"8","key":"9234_CR24","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1093\/jat\/34.8.506","volume":"34","author":"B Levine","year":"2010","unstructured":"Levine B, Phipps RJ, Naso C, Fahie K, Fowler D. Tissue distribution of newer anticonvulsant drugs in postmortem cases. J Anal Toxicol. 2010;34(8):506\u20139.","journal-title":"J Anal Toxicol"},{"issue":"6","key":"9234_CR25","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1093\/jat\/22.6.541","volume":"22","author":"T Vermeulen","year":"1998","unstructured":"Vermeulen T. Distribution of paroxetine in three postmortem cases. J Anal Toxicol. 1998;22(6):541\u20134.","journal-title":"J Anal Toxicol"},{"issue":"29","key":"9234_CR26","doi-asserted-by":"crossref","first-page":"8681","DOI":"10.1007\/s00216-015-9023-5","volume":"407","author":"SN Staeheli","year":"2015","unstructured":"Staeheli SN, Poetzsch M, Kraemer T, Steuer AE. Development and validation of a dynamic range-extended LC-MS\/MS multi-analyte method for 11 different postmortem matrices for redistribution studies applying solvent calibration and additional (13)C isotope monitoring. Anal Bioanal Chem. 2015;407(29):8681\u2013712.","journal-title":"Anal Bioanal Chem"},{"issue":"2","key":"9234_CR27","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s12024-013-9520-9","volume":"10","author":"LC Ebert","year":"2014","unstructured":"Ebert LC, Ptacek W, Breitbeck R, Furst M, Kronreif G, Martinez RM, et al. Virtobot 2.0: the future of automated surface documentation and CT-guided needle placement in forensic medicine. Forensic Sci Med Pathol. 2014;10(2):179\u201386.","journal-title":"Forensic Sci Med Pathol"},{"issue":"1","key":"9234_CR28","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1520\/JFS16084J","volume":"43","author":"AM Langford","year":"1998","unstructured":"Langford AM, Taylor KK, Pounder DJ. Drug concentration in selected skeletal muscles. J Forensic Sci. 1998;43(1):22\u20137.","journal-title":"J Forensic Sci"},{"issue":"2\u20133","key":"9234_CR29","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.forsciint.2006.02.013","volume":"164","author":"KE Rodda","year":"2006","unstructured":"Rodda KE, Drummer OH. The redistribution of selected psychiatric drugs in post-mortem cases. Forensic Sci Int. 2006;164(2\u20133):235\u20139.","journal-title":"Forensic Sci Int"},{"issue":"2","key":"9234_CR30","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/00085030.1995.10757474","volume":"28","author":"M Dalpe-Scott","year":"1995","unstructured":"Dalpe-Scott M, Degouffe M, Garbutt D, Drost M. A comparison of drug concentrations in postmortem cardiac and peripheral blood in 320 cases. Can Soc Forensic Sci J. 1995;28(2):113\u201321.","journal-title":"Can Soc Forensic Sci J"},{"issue":"9","key":"9234_CR31","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1093\/jat\/32.9.782","volume":"32","author":"PR Pos Pok","year":"2008","unstructured":"Pos Pok PR, Haddouche D, Mauras M, Kuhlmann E, Burle J, Salmon T, et al. Cardiac and peripheral blood similarities in the comparison of nordiazepam and bromazepam blood concentrations. J Anal Toxicol. 2008;32(9):782\u20136.","journal-title":"J Anal Toxicol"},{"key":"9234_CR32","unstructured":"Kupiec TC, Allen LV, Basmadjian GP, Canfield DV, Chaturvedi AK, Blank CL, Parker D Post mortem redistribution of paroxetine using the rat as a model. Presented at The American Academy of Forensic Sciences annual meeting San Francisco, California, USA (1998)."},{"key":"9234_CR33","unstructured":"Baselt RC Disposition of toxic drugs and chemicals in man. 8th ed (2008)."},{"key":"9234_CR34","unstructured":"Documed Kompendium Documed AG. www.compendium.ch (2015) Accessed 21.08.2015."}],"container-title":["Analytical and Bioanalytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-015-9234-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00216-015-9234-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-015-9234-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T03:27:10Z","timestamp":1718249230000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00216-015-9234-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,16]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["9234"],"URL":"https:\/\/doi.org\/10.1007\/s00216-015-9234-9","relation":{},"ISSN":["1618-2642","1618-2650"],"issn-type":[{"value":"1618-2642","type":"print"},{"value":"1618-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,16]]}}}