{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T14:48:23Z","timestamp":1780066103879,"version":"3.54.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2017,12,18]],"date-time":"2017-12-18T00:00:00Z","timestamp":1513555200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"NATO Science for Peace and Security Programme","award":["985042"],"award-info":[{"award-number":["985042"]}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology TAIWAN","doi-asserted-by":"crossref","award":["MOST 106-2113-M-001-018"],"award-info":[{"award-number":["MOST 106-2113-M-001-018"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["NSC 102-2923-M-001-04-MY2"],"award-info":[{"award-number":["NSC 102-2923-M-001-04-MY2"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anal Bioanal Chem"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1007\/s00216-017-0792-x","type":"journal-article","created":{"date-parts":[[2017,12,18]],"date-time":"2017-12-18T00:24:37Z","timestamp":1513556677000},"page":"1257-1263","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Microbial biosensing of ciprofloxacin residues in food by a portable lens-free CCD-based analyzer"],"prefix":"10.1007","volume":"410","author":[{"given":"Wei-Chen","family":"Kao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shimshon","family":"Belkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7623-7555","authenticated-orcid":false,"given":"Ji-Yen","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,12,18]]},"reference":[{"key":"792_CR1","first-page":"1645","volume-title":"Microbial pathogens and strategies for combating them: science, technology and education","author":"GS Bbosa","year":"2013","unstructured":"Bbosa GS, Mwebaza N. Global irrational antibiotics\/antibacterial drugs use: a current and future health and environmental consequences. In: Mendez-Vilas A, editor. Microbial pathogens and strategies for combating them: science, technology and education. Badajoz: Formatex Research Center; 2013. p. 1645\u201355."},{"key":"792_CR2","doi-asserted-by":"crossref","first-page":"5649","DOI":"10.1073\/pnas.1503141112","volume":"112","author":"TP Boeckel Van","year":"2015","unstructured":"Van Boeckel TP, Brower C, Gilbert M, Grenfell BT, Levin S, Robinson TP, et al. Global trends in antimicrobial use in food animals. Proc Natl Acad Sci U S A. 2015;112:5649\u201354.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"792_CR3","first-page":"1","volume":"3099","author":"TP Boeckel Van","year":"2015","unstructured":"Van Boeckel TP, Gandra S, Ashok A, Caudron Q, Grenfell BT, Levin SA, et al. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. Lancet Infect Dis. 2015;3099:1\u20139.","journal-title":"Lancet Infect Dis"},{"key":"792_CR4","volume-title":"The state of the world antibiotics","author":"H Gelband","year":"2015","unstructured":"Gelband H, Miller-Petrie M, Pant S, Gandra S, Levinson J, Barter D, et al. The state of the world antibiotics. Washington: Center for Disease Dynamics, Economics & Policy; 2015."},{"key":"792_CR5","unstructured":"European Commission. Commission Regulation (EU) No 37\/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin. 2009. \nhttps:\/\/ec.europa.eu\/health\/sites\/health\/files\/files\/eudralex\/vol-5\/reg_2010_37\/reg_2010_37_en.pdf\n\n."},{"key":"792_CR6","unstructured":"European Commission. Commission Decision 2002\/657\/EC of 12 August 2002 implementing Council Directive 96\/23\/EC concerning the performance of analytical methods and the interpretation of results. 2002. \nhttp:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/PDF\/?uri=CELEX:32002D0657&from=EN\n\n."},{"key":"792_CR7","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.bios.2016.12.005","volume":"90","author":"V Gaudin","year":"2017","unstructured":"Gaudin V. Advances in biosensor development for the screening of antibiotic residues in food products of animal origin \u2013 a comprehensive review. Biosens Bioelectron. 2017;90:363\u201377.","journal-title":"Biosens Bioelectron"},{"key":"792_CR8","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.4315\/0362-028X-70.8.1952","volume":"70","author":"BS Mart\u00edn","year":"2007","unstructured":"Mart\u00edn BS, Cornejo J, Irag\u00fcen D, Hidalgo H, Anad\u00f3n A. Depletion study of enrofloxacin and its metabolite ciprofloxacin in edible tissues and feathers of white leghorn hens by liquid chromatography coupled with tandem mass spectrometry. J Food Prot. 2007;70:1952\u20137.","journal-title":"J Food Prot"},{"key":"792_CR9","doi-asserted-by":"crossref","first-page":"4535","DOI":"10.1021\/jf900513b","volume":"57","author":"Q Tang","year":"2009","unstructured":"Tang Q, Yang T, Tan X, Luo J. Simultaneous determination of fluoroquinolone antibiotic residues in milk sample by solid-phase extraction\u2212liquid chromatography\u2212tandem mass spectrometry. J Agric Food Chem. 2009;57:4535\u20139.","journal-title":"J Agric Food Chem"},{"key":"792_CR10","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1021\/acs.jafc.6b00155","volume":"64","author":"LM Chiesa","year":"2016","unstructured":"Chiesa LM, Nobile M, Panseri S, Biolatti B, Cannizzo FT, Pavlovic R, et al. A liquid chromatography\u2013tandem mass spectrometry method for the detection of antimicrobial agents from seven classes in calf milk replacers: validation and application. J Agric Food Chem. 2016;64:2635\u201340.","journal-title":"J Agric Food Chem"},{"key":"792_CR11","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.bios.2012.03.044","volume":"36","author":"F Conzuelo","year":"2012","unstructured":"Conzuelo F, Gamella M, Campuzano S, Pinacho G, Reviejo D, Marco AJ, et al. Disposable and integrated amperometric immunosensor for direct determination of sulfonamide antibiotics in milk. Biosens Bioelectron. 2012;36:81\u20138.","journal-title":"Biosens Bioelectron"},{"key":"792_CR12","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.bios.2012.12.058","volume":"43","author":"J Dapr\u00e0","year":"2013","unstructured":"Dapr\u00e0 J, Lauridsen LH, Nielsen AT, Rozlosnik N. Comparative study on aptamers as recognition elements for antibiotics in a label-free all-polymer biosensor. Biosens Bioelectron. 2013;43:315\u201320.","journal-title":"Biosens Bioelectron"},{"key":"792_CR13","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.3390\/s100402851","volume":"10","author":"F Ismail","year":"2010","unstructured":"Ismail F, Adeloju SB. Galvanostatic entrapment of penicillinase into polytyramine films and its utilization for the potentiometric determination of penicillin. Sensors. 2010;10:2851\u201368.","journal-title":"Sensors"},{"key":"792_CR14","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.bios.2012.05.017","volume":"38","author":"W Lian","year":"2012","unstructured":"Lian W, Liu S, Yu J, Xing X, Li J, Cui M, et al. Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan\u2013platinum nanoparticles\/graphene\u2013gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. Biosens Bioelectron. 2012;38:163\u20139.","journal-title":"Biosens Bioelectron"},{"key":"792_CR15","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1038\/nrmicro2392","volume":"8","author":"JR Meer van der","year":"2010","unstructured":"van der Meer JR, Belkin S. Where microbiology meets microengineering: design and applications of reporter bacteria. Nat Rev Microbiol. 2010;8:511\u201322.","journal-title":"Nat Rev Microbiol"},{"key":"792_CR16","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1177\/108705710200700205","volume":"7","author":"SJ Valtonen","year":"2002","unstructured":"Valtonen SJ, Kurittu JS, Karp MT. A luminescent Escherichia coli biosensor for the high throughput detection of beta-lactams. J Biomol Screen. 2002;7:127\u201334.","journal-title":"J Biomol Screen"},{"key":"792_CR17","doi-asserted-by":"crossref","first-page":"11065","DOI":"10.1021\/jf801797z","volume":"56","author":"NE Virolainen","year":"2008","unstructured":"Virolainen NE, Pikkemaat MG, Elferink JWA, Karp MT. Rapid detection of tetracyclines and their 4-epimer derivatives from poultry meat with bioluminescent biosensor bacteria. J Agric Food Chem. 2008;56:11065\u201370.","journal-title":"J Agric Food Chem"},{"key":"792_CR18","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1111\/j.1751-7915.2012.00333.x","volume":"5","author":"S Melamed","year":"2012","unstructured":"Melamed S, Lalush C, Elad T, Yagur-Kroll S, Belkin S, Pedahzur R. A bacterial reporter panel for the detection and classification of antibiotic substances. Microb Biotechnol. 2012;5:536\u201348.","journal-title":"Microb Biotechnol"},{"key":"792_CR19","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1007\/s00253-013-5176-3","volume":"98","author":"S Melamed","year":"2014","unstructured":"Melamed S, Naphtaly S, Belkin S. Improved detection of antibiotic compounds by bacterial reporter strains achieved by manipulations of membrane permeability and efflux capacity. Appl Microbiol Biotechnol. 2014;98:2267\u201377.","journal-title":"Appl Microbiol Biotechnol"},{"key":"792_CR20","doi-asserted-by":"crossref","first-page":"337","DOI":"10.3109\/07388551.2010.532767","volume":"31","author":"H Ben-Yoav","year":"2011","unstructured":"Ben-Yoav H, Melamed S, Freeman A, Shacham-Diamand Y, Belkin S. Whole-cell biochips as biosensors: integration of live cells and inanimate surfaces. Crit Rev Bioetechnol. 2011;31:337\u201353.","journal-title":"Crit Rev Bioetechnol"},{"key":"792_CR21","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1039\/C4LC01189A","volume":"15","author":"H Tsai","year":"2015","unstructured":"Tsai H, Tsai Y, Yagur-Kroll S, Palevsky N, Belkin S, Cheng J-Y. Water pollutant monitoring by whole cell array through lens-free detection on CCD. Lab Chip. 2015;15:1472\u201380.","journal-title":"Lab Chip"},{"key":"792_CR22","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.snb.2003.10.022","volume":"99","author":"J-Y Cheng","year":"2004","unstructured":"Cheng J-Y, Wei C-W, Hsu K-H, Young T-H. Direct-write laser micromachining and universal surface modification of PMMA for device development. Sens Actuators B. 2004;99:186\u201396.","journal-title":"Sens Actuators B"},{"key":"792_CR23","first-page":"e53340","volume":"106","author":"HS Hou","year":"2015","unstructured":"Hou HS, Chang H-F, Cheng J-Y. Electrotaxis studies of lung cancer cells using a multichannel dual-electric-field microfluidic chip. J Vis Exp. 2015;106:e53340.","journal-title":"J Vis Exp"},{"key":"792_CR24","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/0003-2697(89)90391-6","volume":"181","author":"R Menzel","year":"1989","unstructured":"Menzel R. A microtiter plate-based system for the semiautomated growth and assay of bacterial cells for \u03b2-galactosidase activity. Anal Biochem. 1989;181:40\u201350.","journal-title":"Anal Biochem"},{"key":"792_CR25","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1751-7915.2009.00149.x","volume":"3","author":"S Yagur Kroll","year":"2010","unstructured":"Yagur Kroll S, Bilic B, Belkin S. Strategies for enhancing bioluminescent bacterial sensor performance by promoter region manipulation. Microb Biotechnol. 2010;3:300\u201310.","journal-title":"Microb Biotechnol"},{"key":"792_CR26","unstructured":"Food and Drug Administration, Department of Health, Taiwan. Method of test for veterinary drug residues in foods-method for multiresidue analysis (2). 2013. \nhttp:\/\/www.fda.gov.tw\/tc\/includes\/GetFile.ashx?mid=133&id=6300&t=s\n\n."}],"container-title":["Analytical and Bioanalytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00216-017-0792-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-017-0792-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-017-0792-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,20]],"date-time":"2018-01-20T01:45:52Z","timestamp":1516412752000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00216-017-0792-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,18]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["792"],"URL":"https:\/\/doi.org\/10.1007\/s00216-017-0792-x","relation":{},"ISSN":["1618-2642","1618-2650"],"issn-type":[{"value":"1618-2642","type":"print"},{"value":"1618-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,18]]}}}