{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T19:16:55Z","timestamp":1793128615032,"version":"4.5.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"22","license":[{"start":{"date-parts":[[2018,2,23]],"date-time":"2018-02-23T00:00:00Z","timestamp":1519344000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anal Bioanal Chem"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1007\/s00216-018-0910-4","type":"journal-article","created":{"date-parts":[[2018,2,23]],"date-time":"2018-02-23T05:14:05Z","timestamp":1519362845000},"page":"5689-5702","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Speciation analysis of arsenic in seafood and seaweed: Part II\u2014single laboratory validation of method"],"prefix":"10.1007","volume":"410","author":[{"given":"Mesay Mulugeta","family":"Wolle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean D.","family":"Conklin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,2,23]]},"reference":[{"key":"910_CR1","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1016\/j.biotechadv.2011.05.017","volume":"29","author":"R Larsen","year":"2011","unstructured":"Larsen R, Eilertsen K-E, Elvevoll EO. Health benefits of marine foods and ingredients. Biotechnol Adv. 2011;29:508\u201318.","journal-title":"Biotechnol Adv"},{"key":"910_CR2","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.jtemb.2015.01.010","volume":"31","author":"M Molin","year":"2015","unstructured":"Molin M, Ulven SM, Meltzer HM, Alexander J. Arsenic in the human food chain, biotransformation and toxicology\u2014review focusing on seafood arsenic. J Trace Elem Med Biol. 2015;31:249\u201359.","journal-title":"J Trace Elem Med Biol"},{"key":"910_CR3","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1351\/PAC-CON-09-07-01","volume":"82","author":"KA Francesconi","year":"2010","unstructured":"Francesconi KA. Arsenic species in seafood: origin and human health implication. Pure Appl Chem. 2010;82:373\u201381.","journal-title":"Pure Appl Chem"},{"key":"910_CR4","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.scitotenv.2016.12.113","volume":"580","author":"V Taylor","year":"2017","unstructured":"Taylor V, Goodale B, Raab A, Schwerdtle T, Reimer K, Conklin S, et al. Human exposure to organic arsenic species from seafood. Sci Total Environ. 2017;580:266\u201382.","journal-title":"Sci Total Environ"},{"key":"910_CR5","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1016\/0045-6535(85)90153-5","volume":"14","author":"T Kaise","year":"1985","unstructured":"Kaise T, Watanabe S, Itoh K. The acute toxicity of arsenobetaine. Chemosphere. 1985;14:1327\u201332.","journal-title":"Chemosphere"},{"key":"910_CR6","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1007\/s00216-010-4303-6","volume":"399","author":"J Feldmann","year":"2011","unstructured":"Feldmann J, Krupp EM. Critical review or scientific opinion paper: arsenosugars\u2014a class of benign arsenic species or justification for developing partly speciated arsenic fractionation in foodstuffs? Anal Bioanal Chem. 2011;399:1735\u201341.","journal-title":"Anal Bioanal Chem"},{"key":"910_CR7","unstructured":"World Health Organization, International Agency for Research on Cancer (IARC Monographs 100), A review of human carcinogens. C. Metals, arsenic, dusts and fibres, 2012, Lyon, France."},{"key":"910_CR8","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1093\/clinchem\/48.1.92","volume":"48","author":"KA Francesconi","year":"2002","unstructured":"Francesconi KA, Tanggaard R, McKenzie CJ, Goessler W. Arsenic metabolites in human urine after ingestion of an arsenosugar. Clin Chem. 2002;48:92\u2013101.","journal-title":"Clin Chem"},{"key":"910_CR9","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1039\/b307457a","volume":"19","author":"M Hulle","year":"2004","unstructured":"Hulle M, Zhang C, Schotte B, Mees L, Vanhaecke F, Vanholder R, et al. Identification of some arsenic species in human urine and blood after ingestion of Chinese seaweed Laminaria. J Anal At Spectrom. 2004;19:58\u201364.","journal-title":"J Anal At Spectrom"},{"key":"910_CR10","doi-asserted-by":"publisher","first-page":"4140","DOI":"10.1021\/es035440f","volume":"38","author":"P Andrewes","year":"2004","unstructured":"Andrewes P, Demarini DM, Funasaka K, Wallace K, Lai VWM, Sun H, et al. Do arsenosugars pose a risk to human health? The comparative toxicities of a trivalent and pentavalent arsenosugar. Environ Sci Technol. 2004;38:4140\u20138.","journal-title":"Environ Sci Technol"},{"key":"910_CR11","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1007\/s00216-006-0401-x","volume":"385","author":"E Schmeisser","year":"2006","unstructured":"Schmeisser E, Goessler W, Francesconi KA. Human metabolism of arsenolipids present in cod liver. Anal Bioanal Chem. 2006;385:367\u201376.","journal-title":"Anal Bioanal Chem"},{"key":"910_CR12","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1039\/C4MT00061G","volume":"6","author":"S Meyer","year":"2014","unstructured":"Meyer S, Matissek M, Muller SM, Taleshi MS, Ebert F, Francesconi KA, et al. In vitro toxicological characterization of three arsenic-containing hydrocarbons. Metallomics. 2014;6:1023\u201333.","journal-title":"Metallomics"},{"key":"910_CR13","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/j.foodchem.2012.02.004","volume":"133","author":"V Sele","year":"2012","unstructured":"Sele V, Sloth JJ, Lundebye A-K, Larsen EH, Berntssen MHG, Amlund H. Arsenolipids in marine oils and fats: a review of occurrence, chemistry and future research needs. Food Chem. 2012;133:618\u201330.","journal-title":"Food Chem"},{"key":"910_CR14","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1039\/B401321M","volume":"129","author":"KA Francesconi","year":"2004","unstructured":"Francesconi KA, Kuehnelt D. Determination of arsenic species: a critical review of methods and applications, 2000\u20132003. Analyst. 2004;129:373\u201395.","journal-title":"Analyst"},{"key":"910_CR15","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1039\/C5JA00155B","volume":"30","author":"WA Maher","year":"2015","unstructured":"Maher WA, Ellwood MJ, Krikowa F, Raber G, Foster S. Measurement of arsenic species in environmental, biological fluids and food samples by HPLC-ICPMS and HPLC-HG-AFS. J Anal At Spectrom. 2015;30:2129\u201383.","journal-title":"J Anal At Spectrom"},{"key":"910_CR16","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s00216-004-2815-7","volume":"381","author":"EH Larsen","year":"2005","unstructured":"Larsen EH, Engman J, Sloth JJ, Hansen M, Jorhem L. Determination of inorganic arsenic in white fish using microwave-assisted alkaline alcoholic sample dissolution and HPLC-ICP-MS. Anal Bioanal Chem. 2005;381:339\u201346.","journal-title":"Anal Bioanal Chem"},{"key":"910_CR17","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1016\/j.foodchem.2013.11.005","volume":"150","author":"\u00c1H P\u00e9tursd\u00f3ttir","year":"2014","unstructured":"P\u00e9tursd\u00f3ttir \u00c1H, Gunnlaugsd\u00f3ttir H, Krupp EM, Feldmann J. Inorganic arsenic in seafood: does the extraction method matter? Food Chem. 2014;150:353\u20139.","journal-title":"Food Chem"},{"key":"910_CR18","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1039\/b402482f","volume":"19","author":"R Wahlen","year":"2004","unstructured":"Wahlen R, McSheehy S, Scriver C, Mester Z. Arsenic speciation in marine certified reference materials part 2. The quantification of water-soluble arsenic species by high-performance liquid chromatography-inductively coupled plasma mass spectrometry. J Anal At Spectrom. 2004;19:876\u201382.","journal-title":"J Anal At Spectrom"},{"key":"910_CR19","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1039\/a807466f","volume":"14","author":"KL Ackley","year":"1999","unstructured":"Ackley KL, B\u2019Hymer C, Sutton KL, Caruso JA. Speciation of arsenic in fish tissue using microwave-assisted extraction followed by HPLC-ICP-MS. J Anal At Spectrom. 1999;14:845\u201350.","journal-title":"J Anal At Spectrom"},{"key":"910_CR20","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1002\/aoc.189","volume":"15","author":"D Kuehnelt","year":"2001","unstructured":"Kuehnelt D, Irgolic KJ, Goessler W. Comparison of three methods for extraction of arsenic compounds from NRCC standard reference material DORM-2 and the brown alga Hijiki fuziforme. Appl Organomet Chem. 2001;15:445\u201356.","journal-title":"Appl Organomet Chem"},{"key":"910_CR21","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1016\/j.talanta.2009.01.003","volume":"78","author":"LH Reyes","year":"2009","unstructured":"Reyes LH, Mar JLG, Rahman GMM, Seybert B, Fahrenholz T, Kingston HM. Simultaneous determination of arsenic and selenium species in fish tissues using microwave-assisted enzymatic extraction and ion chromatography\u2013inductively coupled plasma mass spectrometry. Talanta. 2009;78:983\u201390.","journal-title":"Talanta"},{"key":"910_CR22","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1016\/j.talanta.2010.10.050","volume":"83","author":"A Leufroy","year":"2011","unstructured":"Leufroy A, No\u00ebl L, Dufailly V, Beauchemin D, Gu\u00e9rin T. Determination of seven arsenic species in seafood by ion exchange chromatography coupled to inductively coupled plasma-mass spectrometry following microwave assisted extraction: method validation and occurrence data. Talanta. 2011;83:770\u20139.","journal-title":"Talanta"},{"key":"910_CR23","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1016\/j.foodchem.2014.10.102","volume":"173","author":"AV Zmozinski","year":"2015","unstructured":"Zmozinski AV, Llorente-Mirandes T, L\u00f3pez-S\u00e1nchez JF, da Silva MM. Establishment of a method for determination of arsenic species in seafood by LC-ICP-MS. Food Chem. 2015;173:1073\u201382.","journal-title":"Food Chem"},{"key":"910_CR24","doi-asserted-by":"publisher","unstructured":"Wolle MM, Conklin SD. Speciation analysis of arsenic in seafood and seaweed: part I\u2014evaluation and optimization of methods. Anal Bioanal Chem. https:\/\/doi.org\/10.1007\/s00216-018-0906-0","DOI":"10.1007\/s00216-018-0906-0"},{"key":"910_CR25","unstructured":"US FDA Office of Foods and Veterinary Medicine, Guidelines for validation of chemical methods for the FDA Foods and Veterinary Medicine Program, 2nd ed., April 2015 ( https:\/\/www.fda.gov\/downloads\/ScienceResearch\/FieldScience\/UCM273418.pdf )."},{"key":"910_CR26","unstructured":"US FDA Elemental Analysis Manual for Food and Related Products, Section 4.7. Inductively Coupled Plasma-Mass Spectrometric Determination of Arsenic, Cadmium, Chromium, Lead, Mercury, and Other Elements in Food Using Microwave Assisted Digestion, Version 1.1, March 2015 ( https:\/\/www.fda.gov\/Food\/FoodScienceResearch\/LaboratoryMethods\/ucm2006954.htm )."},{"key":"910_CR27","unstructured":"US FDA Elemental Analysis Manual for Food and Related Products, Section 3.2. Terminology, September 2015 ( https:\/\/www.fda.gov\/Food\/FoodScienceResearch\/LaboratoryMethods\/ucm2006954.htm )."},{"key":"910_CR28","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1039\/b402994a","volume":"19","author":"JJ Sloth","year":"2004","unstructured":"Sloth JJ, Larsen EH, Julshamn K. Selective arsenic speciation analysis of human urine reference materials using gradient elution ion-exchange HPLC-ICP-MS. J Anal At Spectrom. 2004;19:973\u20138.","journal-title":"J Anal At Spectrom"},{"key":"910_CR29","unstructured":"Codex Alimentarius Commission, Procedural Manual, 24th ed., 2015, Rome, Italy."},{"key":"910_CR30","unstructured":"US FDA Elemental Analysis Manual for Food and Related Products, Section 4.10. High Performance Liquid Chromatography-Inductively Coupled Plasma-Mass Spectrometric Determination of Four Arsenic Species in Fruit Juice, Version 1.0, July 2013 ( https:\/\/www.fda.gov\/Food\/FoodScienceResearch\/LaboratoryMethods\/ucm2006954.htm )."},{"key":"910_CR31","unstructured":"US FDA Elemental Analysis Manual for Food and Related Products, Section 4.11. Arsenic Speciation in Rice and Rice Products Using High Performance Liquid Chromatography-Inductively Coupled Plasma-Mass Spectrometric Determination, Version Draft 1.1, November 2012 ( https:\/\/www.fda.gov\/Food\/FoodScienceResearch\/LaboratoryMethods\/ucm2006954.htm )."},{"key":"910_CR32","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1016\/j.jinorgbio.2004.03.010","volume":"98","author":"NA Rey","year":"2004","unstructured":"Rey NA, Howarth OW, Pereira-Maia EC. Equilibrium characterization of the as(III)\u2013cysteine and the as(III)\u2013glutathione systems in aqueous solution. J Inorg Biochem. 2004;98:1151\u20139.","journal-title":"J Inorg Biochem"},{"key":"910_CR33","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1021\/tx034053g","volume":"16","author":"G Jiang","year":"2003","unstructured":"Jiang G, Gong Z, Li X-F, Cullen WR, Le XC. Interaction of trivalent arsenicals with metallothioneins. Chem Res Toxicol. 2003;16:873\u201380.","journal-title":"Chem Res Toxicol"},{"key":"910_CR34","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1021\/tx049756s","volume":"17","author":"M Lu","year":"2004","unstructured":"Lu M, Wang H, Li X-F, Lu X, Cullen WR, Arnold LL, et al. Evidence of hemoglobin binding to arsenic as a basis for the accumulation of arsenic in rat blood. Chem Res Toxicol. 2004;17:1733\u201342.","journal-title":"Chem Res Toxicol"},{"key":"910_CR35","doi-asserted-by":"publisher","first-page":"3658","DOI":"10.1002\/rcm.3263","volume":"21","author":"Z Wang","year":"2007","unstructured":"Wang Z, Zhang H, Li X-F, Le XC. Study of interactions between arsenicals and thioredoxins (human and E. coli) using mass spectrometry. Rapid Commun Mass Spectrom. 2007;21:3658\u201366.","journal-title":"Rapid Commun Mass Spectrom"},{"key":"910_CR36","first-page":"838","volume":"2014","author":"JR Winther","year":"1840","unstructured":"Winther JR, Thorpe C. Quantification of thiols and disulfides. Biochim Biophys Acta. 1840;2014:838\u201346.","journal-title":"Biochim Biophys Acta"},{"key":"910_CR37","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1351\/PAC-CON-11-09-30","volume":"84","author":"T Llorente-Mirandes","year":"2012","unstructured":"Llorente-Mirandes T, Calder\u00f3n J, L\u00f3pez-S\u00e1nchez JF, Centrich F, Rubio R. A fully validated method for the determination of arsenic species in rice and infant cereal products. Pure Appl Chem. 2012;84:225\u201338.","journal-title":"Pure Appl Chem"},{"key":"910_CR38","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.gexplo.2012.07.003","volume":"121","author":"A Ruttens","year":"2012","unstructured":"Ruttens A, Blanpain AC, De Temmerman L, Waegeneers N. Arsenic speciation in food in Belgium, part 1: fish, molluscs and crustaceans. J Geochem Explor. 2012;121:55\u201361.","journal-title":"J Geochem Explor"},{"key":"910_CR39","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1016\/j.foodchem.2008.08.001","volume":"113","author":"X Cao","year":"2009","unstructured":"Cao X, Hao C, Wang G, Yang H, Chen D, Wang X. Sequential extraction combined with HPLC\u2013ICP-MS for As speciation in dry seafood products. Food Chem. 2009;113:720\u20136.","journal-title":"Food Chem"},{"key":"910_CR40","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.jtemb.2013.11.004","volume":"28","author":"KO Amayo","year":"2014","unstructured":"Amayo KO, Raab A, Krupp EM, Marschall T, Horsfall M Jr, Feldmann J. Arsenolipids show different profiles in muscle tissues of four commercial fish species. J Trace Elem Med Biol. 2014;28:131\u20137.","journal-title":"J Trace Elem Med Biol"},{"key":"910_CR41","doi-asserted-by":"publisher","first-page":"10282","DOI":"10.1021\/ac502488f","volume":"86","author":"RA Glabonjat","year":"2014","unstructured":"Glabonjat RA, Raber G, Jensen KB, Ehgartner J, Francesconi KA. Quantification of arsenolipids in the certified reference material NMIJ 7405-a (Hijiki) using HPLC\/mass spectrometry after chemical derivatization. Anal Chem. 2014;86:10282\u20137.","journal-title":"Anal Chem"},{"key":"910_CR42","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.scitotenv.2004.12.071","volume":"348","author":"E Argese","year":"2005","unstructured":"Argese E, Bettiol C, Rigo C, Bertini S, Colomban S, Ghetti PF. Distribution of arsenic compounds in Mytilus galloprovincialis of the Venice lagoon (Italy). Sci Total Environ. 2005;348:267\u201377.","journal-title":"Sci Total Environ"}],"container-title":["Analytical and Bioanalytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00216-018-0910-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-018-0910-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-018-0910-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T15:23:56Z","timestamp":1603898636000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00216-018-0910-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,23]]},"references-count":42,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["910"],"URL":"https:\/\/doi.org\/10.1007\/s00216-018-0910-4","relation":{},"ISSN":["1618-2642","1618-2650"],"issn-type":[{"value":"1618-2642","type":"print"},{"value":"1618-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,23]]},"assertion":[{"value":"29 November 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 January 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 February 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}