{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T12:36:56Z","timestamp":1768826216382,"version":"3.49.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"15","license":[{"start":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T00:00:00Z","timestamp":1554681600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anal Bioanal Chem"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1007\/s00216-019-01812-3","type":"journal-article","created":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T02:03:40Z","timestamp":1554689020000},"page":"3353-3360","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Microporous polymer based on the new compound \u201cbi-(4-vinyl phenylquinoline) amide\u201d for enrichment and quantitative determination of lamotrigine in rat and human serum"],"prefix":"10.1007","volume":"411","author":[{"given":"Mengzhe","family":"Guo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lili","family":"Shao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zengting","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tonghui","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daoquan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,4,8]]},"reference":[{"key":"1812_CR1","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.eplepsyres.2013.02.002","volume":"105","author":"L Gu","year":"2014","unstructured":"Gu L, Liang B, Chen Q, Long JX, Xie JJ, Wu GL, et al. Prevalence of epilepsy in the People\u2019s Republic of China: a systematic review. Epilepsy Res. 2014;105:195\u2013205.","journal-title":"Epilepsy Res"},{"key":"1812_CR2","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.neulet.2017.01.014","volume":"667","author":"S Balestrini","year":"2018","unstructured":"Balestrini S, Sisodiya SM. Pharmacogenomics in epilepsy. Neurosci Lett. 2018;667:27\u201339.","journal-title":"Neurosci Lett"},{"key":"1812_CR3","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1111\/joim.12322","volume":"227","author":"LE Walker","year":"2015","unstructured":"Walker LE, Mirza N, Yip VLM, Marson AG, Pirmohamed M. Personalized medicine approaches in epilepsy. J Intern Med. 2015;227:218\u201334.","journal-title":"J Intern Med"},{"key":"1812_CR4","doi-asserted-by":"publisher","first-page":"377","DOI":"10.2741\/713","volume":"6","author":"MA Lopez-Garcia","year":"2014","unstructured":"Lopez-Garcia MA, Feria-Romero IA, Fernando-Serrano H, Escalante-Santiago D, Grijalva I, Orozco-Suarez S. Genetic polymorphisms associated with antiepileptic metabolism. Front Biosci. 2014;6:377\u201386.","journal-title":"Front Biosci"},{"key":"1812_CR5","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1111\/bcp.13047","volume":"82","author":"S Cremers","year":"2016","unstructured":"Cremers S, Guha N, Shine B. Therapeutic drug monitoring in the era of precision medicine: opportunities. Br J Clin Pharmacol. 2016;82:900\u20132.","journal-title":"Br J Clin Pharmacol"},{"key":"1812_CR6","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.talanta.2013.10.026","volume":"119","author":"M Vosough","year":"2014","unstructured":"Vosough M, Ghafghazi S, Sabetkasaei M. Chemometrics enhanced HPLC-DAD performance for rapid quantification of carbamazepine and phenobarbital in human serum samples. Talanta. 2014;119:17\u201323.","journal-title":"Talanta."},{"key":"1812_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jchromb.2013.02.026","volume":"925","author":"A Serralheiro","year":"2013","unstructured":"Serralheiro A, Alves G, Fortuna A, Rocha M, Falcao A. First HPLC-UV method for rapid and simultaneous quantification of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10,11-epoxide, 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine, lamotrigine, oxcarbazepine and licarbazepine in human plasma. J Chromatogr B. 2013;925:1\u20139.","journal-title":"J Chromatogr B"},{"key":"1812_CR8","doi-asserted-by":"publisher","first-page":"10396","DOI":"10.1021\/ja4028346","volume":"135","author":"R Yin","year":"2013","unstructured":"Yin R, Mao SQ, Zhao BL, Chong ZC, Yang Y, Zhao C, et al. Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals. J Am Chem Soc. 2013;135:10396\u2013403.","journal-title":"J Am Chem Soc"},{"key":"1812_CR9","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.aca.2015.01.047","volume":"865","author":"MZ Guo","year":"2015","unstructured":"Guo MZ, Zhai YX, Guo C, Liu YQ, Tang DQ, Pan YJ. A new strategy to determine the protein mutation site using matrix-assisted laser desorption ionization in-source decay: derivatization by ionic liquid. Anal Chem Acta. 2015;865:31\u20138.","journal-title":"Anal Chem Acta"},{"key":"1812_CR10","doi-asserted-by":"publisher","first-page":"103662","DOI":"10.1039\/C5RA18595E","volume":"5","author":"MZ Guo","year":"2015","unstructured":"Guo MZ, Weng GF, Yin DY, Hu XX, Han J, Du Y, et al. Identification of the over alkylation sites of a protein by IAM in MALDI-TOF\/TOF tandem mass spectrometry. RSC Adv. 2015;5:103662\u20138.","journal-title":"RSC Adv"},{"key":"1812_CR11","doi-asserted-by":"publisher","first-page":"4734","DOI":"10.1002\/anie.201000827","volume":"49","author":"A Schlossbauer","year":"2010","unstructured":"Schlossbauer A, Warncke S, Gramlich PME, Kecht J, Manetto A, Carell T, et al. A programmable DNA-based molecular valve for colloidal mesoporous silica. Angew Chem Int Ed. 2010;49:4734\u20137.","journal-title":"Angew Chem Int Ed"},{"key":"1812_CR12","doi-asserted-by":"publisher","first-page":"3428","DOI":"10.1002\/jssc.201600432","volume":"39","author":"MZ Guo","year":"2016","unstructured":"Guo MZ, Yin DY, Han J, Zhang LY, Li X, He DD, et al. Phenylboronic acid modified solid-phase extraction column: preparation, characterization, and application to the analysis of amino acids in sepia capsule by removing the maltose. J Sep Sci. 2016;39:3428\u201335.","journal-title":"J Sep Sci"},{"key":"1812_CR13","doi-asserted-by":"publisher","first-page":"4942","DOI":"10.1021\/ac200679t","volume":"83","author":"H Yan","year":"2011","unstructured":"Yan H, Ahmad-Tajudin A, Bengtsson M, Xiao SJ, Laurell T, Ekstrom S. Noncovalent antibody immobilization on porous silicon combined with miniaturized solid-phase extraction (SPE) for array based immunoMALDI assays. Anal Chem. 2011;83:4942\u20138.","journal-title":"Anal Chem"},{"key":"1812_CR14","doi-asserted-by":"publisher","first-page":"6885","DOI":"10.1021\/ac4011364","volume":"85","author":"Y Hu","year":"2013","unstructured":"Hu Y, Huang Z, Liao J, Li GK. Chemical bonding approach for fabrication of hybrid magnetic metal-organic framework-5: high efficient adsorbents for magnetic enrichment of trace analytes. Anal Chem. 2013;85:6885\u201393.","journal-title":"Anal Chem"},{"key":"1812_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.chroma.2015.09.059","volume":"1419","author":"C Zhang","year":"2015","unstructured":"Zhang C, Li G, Zhang Z. A hydrazone covalent organic polymer based micro-solid phase extraction for online analysis of trace Sudan dyes in food samples. J Chromatogr A. 2015;1419:1\u20139.","journal-title":"J Chromatogr A"},{"key":"1812_CR16","doi-asserted-by":"publisher","first-page":"8738","DOI":"10.1021\/ja303448r","volume":"134","author":"X Liu","year":"2012","unstructured":"Liu X, Xu Y, Jiang D. Conjugated microporous polymers as molecular sensing devices: microporous architecture enables rapid response and enhances sensitivity in fluorescence-on and fluorescence-off sensing. J Am Chem Soc. 2012;134:8738\u201341.","journal-title":"J Am Chem Soc"},{"key":"1812_CR17","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1002\/marc.201100865","volume":"33","author":"Z Xiang","year":"2012","unstructured":"Xiang Z, Cao D. Synthesis of luminescent covalent-organic polymers for detecting nitroaromatic explosives and small organic molecules. Macromol Rapid Commun. 2012;33:1184\u201390.","journal-title":"Macromol Rapid Commun"},{"key":"1812_CR18","doi-asserted-by":"publisher","first-page":"6930","DOI":"10.1021\/acs.analchem.6b01708","volume":"88","author":"LJ Zhou","year":"2016","unstructured":"Zhou LJ, Hu YL, Li GK. Conjugated microporous polymers with built-in magnetic nanoparticles for excellent enrichment of trace hydroxylated polycyclic aromatic hydrocarbons in human urine. Anal Chem. 2016;88:6930\u20138.","journal-title":"Anal Chem"},{"key":"1812_CR19","doi-asserted-by":"publisher","first-page":"3373","DOI":"10.1021\/ac504594d","volume":"87","author":"JL Pan","year":"2015","unstructured":"Pan JL, Jia S, Li GK, Hu YL. Organic building block based microporous network SNW-1 coating fabricated by multi-layer interbridging strategy for efficient enrichment of trace volatiles. Anal Chem. 2015;87:3373\u201381.","journal-title":"Anal Chem"},{"key":"1812_CR20","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1002\/pi.4640","volume":"63","author":"Q Liu","year":"2014","unstructured":"Liu Q, Tang Z, Wu M, Zhou ZH. Design, preparation and application of conjugated microporous polymers. Polym Int. 2014;63:381\u201392.","journal-title":"Polym Int"},{"key":"1812_CR21","doi-asserted-by":"publisher","first-page":"13422","DOI":"10.1039\/C4TA01871K","volume":"2","author":"YW Zhang","year":"2014","unstructured":"Zhang YW, Sigen A, Zou YC, Luo XL, Li ZP, Xia H, et al. Gas uptake, molecular sensing and organocatalytic performances of a multifunctional carbazole-based conjugated microporous polymer. J Mater Chem A. 2014;2:13422\u201330.","journal-title":"J Mater Chem A"},{"key":"1812_CR22","doi-asserted-by":"publisher","first-page":"6447","DOI":"10.1039\/c3ra46988c","volume":"4","author":"XM Liu","year":"2014","unstructured":"Liu XM, Sigen A, Zhang YW, Luo XL, Xia H, Li H, et al. A porphyrin-linked conjugated microporous polymer with selective carbon dioxide adsorption and heterogeneous organocatalytic performances. RSC Adv. 2014;4:6447\u201353.","journal-title":"RSC Adv"},{"key":"1812_CR23","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.chroma.2014.03.058","volume":"1342","author":"ZS Liu","year":"2014","unstructured":"Liu ZS, Ou JJ, Lin H, Wang HW, Dong J, Zou HF. Preparation of polyhedral oligomeric silsesquioxane-based hybrid monolith by ring-opening polymerization and post-functionalization via thiol-ene click reaction. J Chromatogr A. 2014;1342:70\u20137.","journal-title":"J Chromatogr A"},{"key":"1812_CR24","doi-asserted-by":"publisher","first-page":"12334","DOI":"10.1021\/ac503626v","volume":"86","author":"ZS Liu","year":"2014","unstructured":"Liu ZS, Ou JJ, Lin H, Wang HW, Liu ZY, Dong J, et al. Preparation of monolithic polymer columns with homogeneous structure via photoinitiated thiol-yne click polymerization and their application in separation of small molecules. Anal Chem. 2014;86:12334\u201340.","journal-title":"Anal Chem"},{"key":"1812_CR25","doi-asserted-by":"publisher","first-page":"3906","DOI":"10.1021\/acs.analchem.7b04755","volume":"90","author":"MZ Guo","year":"2018","unstructured":"Guo MZ, Zhang LY, Du Y, Du WC, Liu DT, Guo C, et al. Enrichment and quantitative determination of 5-(hydroxymethyl)-2'-deoxycytidine, 5-(formyl)-2'-deoxycytidine, and 5-(carboxyl)-2'-deoxycytidine in human urine of breast cancer patients by magnetic hyper-cross-linked microporous polymers based on polyionic liquid. Anal Chem. 2018;90:3906\u201313.","journal-title":"Anal Chem"}],"container-title":["Analytical and Bioanalytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-019-01812-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00216-019-01812-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-019-01812-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T23:20:17Z","timestamp":1586215217000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00216-019-01812-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,8]]},"references-count":25,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["1812"],"URL":"https:\/\/doi.org\/10.1007\/s00216-019-01812-3","relation":{},"ISSN":["1618-2642","1618-2650"],"issn-type":[{"value":"1618-2642","type":"print"},{"value":"1618-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,8]]},"assertion":[{"value":"10 December 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Informed consent was obtained from all individual participants included in the study and the experiments were approved by the ethics committee.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}