{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T01:09:18Z","timestamp":1778807358183,"version":"3.51.4"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"26","license":[{"start":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T00:00:00Z","timestamp":1596153600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T00:00:00Z","timestamp":1596153600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anal Bioanal Chem"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s00216-020-02845-9","type":"journal-article","created":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T03:45:36Z","timestamp":1596253536000},"page":"7123-7130","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["An improved drop casting electrochemical strategy for furosemide quantification in natural waters exploiting chemically reduced graphene oxide on glassy carbon electrodes"],"prefix":"10.1007","volume":"412","author":[{"given":"Sancler C.","family":"Vasconcelos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo M.","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo G.","family":"de Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u00e1bio G.","family":"Lepri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wagner F.","family":"Pacheco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe S.","family":"Semaan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael M.","family":"Dornellas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,31]]},"reference":[{"key":"2845_CR1","doi-asserted-by":"publisher","first-page":"2544","DOI":"10.1002\/jps.22030","volume":"99","author":"GE Granero","year":"2010","unstructured":"Granero GE, Longhi MR, Mora MJ, Junginger HE, Midha KK, Shah VP, et al. Biowaiver monographs for immediate release solid oral dosage forms: furosemide. J Pharm Sci. 2010;99:2544\u201356.","journal-title":"J Pharm Sci"},{"key":"2845_CR2","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/S0731-7085(03)00229-2","volume":"33","author":"YS El-Saharty","year":"2003","unstructured":"El-Saharty YS. Simultaneous high-performance liquid chromatographic assay of furosemide and propranolol HCL and its application in a pharmacokinetic study. J Pharm Biomed Anal. 2003;33:699\u2013709.","journal-title":"J Pharm Biomed Anal"},{"key":"2845_CR3","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.jddst.2018.03.005","volume":"45","author":"T Gulsun","year":"2018","unstructured":"Gulsun T, Borna SE, Vural I, Sahin S. Preparation and characterization of furosemide nanosuspensions. J Drug Deliv Sci Technol. 2018;45:93\u2013100.","journal-title":"J Drug Deliv Sci Technol"},{"key":"2845_CR4","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1134\/S1061934809100141","volume":"64","author":"VA Doroshchuk","year":"2009","unstructured":"Doroshchuk VA, Gonta NA, Drozdova MV, Kulichenko SA. Determination of furosemide in urine by HPLC with preconcentration by micellar-extraction. J Anal Chem. 2009;64:1054\u20138.","journal-title":"J Anal Chem"},{"key":"2845_CR5","doi-asserted-by":"publisher","first-page":"74","DOI":"10.2478\/achi-2018-0006","volume":"26","author":"RR Chavan","year":"2018","unstructured":"Chavan RR, Bhinge SD, Bhutkar MA, Randive DS. Development and validation of spectrophotometric methods for simultaneous estimation of citicoline and piracetam in tablet dosage form. ACTA Chem IASI. 2018;26:74\u201390.","journal-title":"ACTA Chem IASI"},{"key":"2845_CR6","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/0378-5173(88)90178-0","volume":"42","author":"H Bundgaard","year":"1988","unstructured":"Bundgaard H, N\u00f8rgaard T, Nielsen NM. Photodegradation and hydrolysis of furosemide and furosemide esters in aqueous solutions. Int J Pharm. 1988;42:217\u201324.","journal-title":"Int J Pharm"},{"key":"2845_CR7","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/0378-5173(79)90034-6","volume":"2","author":"JE Cruz","year":"1979","unstructured":"Cruz JE, Maness DD, Yakatan GJ. Kinetics and mechanism of hydrolysis of furosemide. Int J Pharm. 1979;2:275\u201381.","journal-title":"Int J Pharm"},{"key":"2845_CR8","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.chroma.2012.06.012","volume":"1249","author":"JP Bagnall","year":"2012","unstructured":"Bagnall JP, Evans SE, Wort MT, Lubben AT, Kasprzyk-Hordern B. Using chiral liquid chromatography quadrupole time-of-flight mass spectrometry for the analysis of pharmaceuticals and illicit drugs in surface and wastewater at the enantiomeric level. J Chromatogr A. 2012;1249:115\u201329.","journal-title":"J Chromatogr A"},{"key":"2845_CR9","doi-asserted-by":"publisher","first-page":"22691","DOI":"10.1007\/s11356-016-7398-2","volume":"23","author":"H Olvera-Vargas","year":"2016","unstructured":"Olvera-Vargas H, Leroy S, Rivard M, Oturan N, Oturan M, Buisson D. Microbial biotransformation of furosemide for environmental risk assessment: identification of metabolites and toxicological evaluation. Environ Sci Pollut Res. 2016;23:22691\u2013700.","journal-title":"Environ Sci Pollut Res"},{"key":"2845_CR10","doi-asserted-by":"crossref","unstructured":"Snyder LR, Kirkland JJ, Dolan JW. Introduction to modern liquid chromatography. 2nd ed. New York; 2010.","DOI":"10.1002\/9780470508183"},{"key":"2845_CR11","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1081\/AL-200065813","volume":"38","author":"FS Semaan","year":"2005","unstructured":"Semaan FS, Neto AJDS, Lan\u00e7as FM, Gomes Cavalheiro \u00c9T. Rapid HPLC-DAD determination of furosemide in tablets using a short home-made column. Anal Lett. 2005;38:1651\u20138.","journal-title":"Anal Lett"},{"key":"2845_CR12","first-page":"34","volume":"22","author":"FS Semaan","year":"2005","unstructured":"Semaan FS, De Sousa RA, Cavalheiro \u00c9TG. Flow injection spectrophotometric determination of furosemide in pharmaceuticals by the bleaching of a permanganate carrier solution. J Flow Inject Anal. 2005;22:34\u20137.","journal-title":"J Flow Inject Anal"},{"key":"2845_CR13","doi-asserted-by":"publisher","first-page":"2557","DOI":"10.1080\/00032710600824698","volume":"39","author":"FS Semaan","year":"2006","unstructured":"Semaan FS, Cavalheiro \u00c9TG. Spectrophotometric determination of furosemide based on its complexation with Fe(III) in ethanolic medium using a flow injection procedure. Anal Lett. 2006;39:2557\u201367.","journal-title":"Anal Lett"},{"key":"2845_CR14","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1080\/00032710701746782","volume":"41","author":"FS Semaan","year":"2008","unstructured":"Semaan FS, Nogueira PA, Cavalheiro \u00c9TG. Flow-based fluorimetric determination of furosemide in pharmaceutical formulations and biological samples: use of micelar media to improve sensitivity. Anal Lett. 2008;41:66\u201379.","journal-title":"Anal Lett"},{"key":"2845_CR15","doi-asserted-by":"publisher","first-page":"30","DOI":"10.26850\/1678-4618eqj.v37.1.2012.p30-37","volume":"37","author":"AA Da Silva Neto","year":"2012","unstructured":"Da Silva Neto AA, Pacheco WF, Semaan FS. Spectrophotometric determination of furosemide in pharmaceutical formulations - a didactic approach, from practice to theory. Ecletica Quim. 2012;37:30\u20137.","journal-title":"Ecletica Quim"},{"key":"2845_CR16","doi-asserted-by":"publisher","first-page":"2287","DOI":"10.1002\/elan.200804329","volume":"20","author":"FS Semaan","year":"2008","unstructured":"Semaan FS, Pinto EM, Cavalheiro \u00c9TG, Brett CMA. A graphite-polyurethane composite electrode for the analysis of furosemide. Electroanalysis. 2008;20:2287\u201393.","journal-title":"Electroanalysis."},{"key":"2845_CR17","doi-asserted-by":"publisher","first-page":"6580","DOI":"10.1039\/c3ra46973e","volume":"4","author":"M Hasanzadeh","year":"2014","unstructured":"Hasanzadeh M, Pournaghi-Azar MH, Shadjou N, Jouyban A. A new mechanistic approach to elucidate furosemide electrooxidation on magnetic nanoparticles loaded on graphene oxide modified glassy carbon electrode. RSC Adv. 2014;4:6580\u201390.","journal-title":"RSC Adv"},{"key":"2845_CR18","doi-asserted-by":"publisher","first-page":"1692","DOI":"10.5935\/1984-6835.20150096","volume":"7","author":"RX De Mendon\u00e7a","year":"2015","unstructured":"De Mendon\u00e7a RX, Buzzetti PHM, Silva AL, Ara\u00fajo AS, Ponzio EA, Semaan FS. Voltammetric determination of sildenafil citrate and furosemide at composite electrodes of graphite-paraffin for use in samples of pharmaceutical and toxicological interests. Rev Virtual Quim. 2015;7:1692\u2013708.","journal-title":"Rev Virtual Quim"},{"key":"2845_CR19","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.talanta.2015.08.042","volume":"146","author":"K Kor","year":"2016","unstructured":"Kor K, Zarei K. Development and characterization of an electrochemical sensor for furosemide detection based on electropolymerized molecularly imprinted polymer. Talanta. 2016;146:181\u20137.","journal-title":"Talanta."},{"key":"2845_CR20","doi-asserted-by":"publisher","first-page":"1242","DOI":"10.1016\/j.msec.2015.09.062","volume":"58","author":"R Heidarimoghadam","year":"2016","unstructured":"Heidarimoghadam R, Farmany A. Rapid determination of furosemide in drug and blood plasma of wrestlers by a carboxyl-MWCNT sensor. Mater Sci Eng C. 2016;58:1242\u20135.","journal-title":"Mater Sci Eng C"},{"key":"2845_CR21","doi-asserted-by":"crossref","unstructured":"Attaallah R, Antonacci A, Arduini F, Amine A, Scognamiglio V. Nanobiosensors for bioclinical applications: pros and cons. Green Nanoparticles. 2020:117\u201349.","DOI":"10.1007\/978-3-030-39246-8_5"},{"key":"2845_CR22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/nano10071268","volume":"10","author":"\u00c1 Torrinha","year":"2020","unstructured":"Torrinha \u00c1, Oliveira TMBF, Ribeiro FWP, Correia AN, Lima-Neto P, Morais S. Application of nanostructured carbon-based electrochemical (bio)sensors for screening of emerging pharmaceutical pollutants in waters and aquatic species: a review. Nanomaterials. 2020;10:1\u201329.","journal-title":"Nanomaterials."},{"key":"2845_CR23","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.electacta.2015.10.065","volume":"197","author":"RA Medeiros","year":"2016","unstructured":"Medeiros RA, Baccarin M, Fatibello-Filho O, Rocha-Filho RC, Deslouis C, Debiemme-Chouvy C. Comparative study of basal-plane pyrolytic graphite, boron-doped diamond, and amorphous carbon nitride electrodes for the voltammetric determination of furosemide in pharmaceutical and urine samples. Electrochim Acta. 2016;197:179\u201385.","journal-title":"Electrochim Acta"},{"key":"2845_CR24","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1021\/ac00010a025","volume":"63","author":"J Wang","year":"1991","unstructured":"Wang J, Taha Z. Batch injection analysis. Anal Chem. 1991;63:1053\u20136.","journal-title":"Anal Chem"},{"key":"2845_CR25","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1002\/elan.200302878","volume":"16","author":"MSM Quintino","year":"2004","unstructured":"Quintino MSM, Angnes L. Batch injection analysis: an almost unexplored powerful tool. Electroanalysis. 2004;16:513\u201323.","journal-title":"Electroanalysis."},{"key":"2845_CR26","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1002\/elan.201500466","volume":"28","author":"ES Almeida","year":"2016","unstructured":"Almeida ES, Richter EM, Munoz RAA. Voltammetric lead determination in aviation fuel samples using a screen-printed gold electrode and batch-injection analysis. Electroanalysis. 2016;28:633\u20139.","journal-title":"Electroanalysis."},{"key":"2845_CR27","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1016\/j.talanta.2015.06.048","volume":"146","author":"JM Freitas","year":"2016","unstructured":"Freitas JM, Oliveira TDC, Gimenes DT, Munoz RAA, Richter EM. Simultaneous determination of three species with a single-injection step using batch injection analysis with multiple pulse amperometric detection. Talanta. 2016;146:670\u20135.","journal-title":"Talanta."},{"key":"2845_CR28","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.snb.2016.02.139","volume":"231","author":"RHO Montes","year":"2016","unstructured":"Montes RHO, Lima AP, Dos Santos VB, Vidal DTR, Do Lago CL, Richter EM, et al. Carbon-nanotube amperometric sensor for selective determination of 4-chloroaniline in commercial chlorhexidine solutions. Sensors Actuators B Chem. 2016;231:38\u201344.","journal-title":"Sensors Actuators B Chem"},{"key":"2845_CR29","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1002\/elan.1140080713","volume":"8","author":"JJ Pedrotti","year":"1996","unstructured":"Pedrotti JJ, Angnes L, Gutz IGR. Miniaturized reference electrodes with microporous polymer junctions. Electroanalysis. 1996;8:673\u20135.","journal-title":"Electroanalysis."},{"key":"2845_CR30","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1016\/j.snb.2017.07.070","volume":"254","author":"DP Rocha","year":"2018","unstructured":"Rocha DP, Dornellas RM, Cardoso RM, Narciso LCD, Silva MNT, Nossol E, et al. Chemically versus electrochemically reduced graphene oxide: improved amperometric and voltammetric sensors of phenolic compounds on higher roughness surfaces. Sensors Actuators B Chem. 2018;254:701\u20138.","journal-title":"Sensors Actuators B Chem"},{"key":"2845_CR31","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.aca.2018.06.021","volume":"1033","author":"RM Cardoso","year":"2018","unstructured":"Cardoso RM, Mendon\u00e7a DMH, Silva WP, Silva MNT, Nossol E, da Silva RAB, et al. 3D printing for electroanalysis: from multiuse electrochemical cells to sensors. Anal Chim Acta. 2018;1033:49\u201357.","journal-title":"Anal Chim Acta"},{"key":"2845_CR32","first-page":"429","volume":"31","author":"FD Da Silva","year":"2020","unstructured":"Da Silva FD, Rocha DP, Silva MNT, Nossol E, Mu\u00f1oz RAA, Semaan FS, et al. Chemically reduced graphene oxide on gold electrodes from recordable CDs: characterization and potential sensing applications. J Braz Chem Soc. 2020;31:429\u201337.","journal-title":"J Braz Chem Soc"},{"key":"2845_CR33","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/0378-4347(95)00349-5","volume":"675","author":"MB Barroso","year":"1996","unstructured":"Barroso MB, Jim\u00e9nez RM, Alonso RM, Ortiz E. Determination of piretanide and furosemide in pharmaceuticals and human urine by high-performance liquid chromatography with amperometric detection. J Chromatogr B. 1996;675:303\u201312.","journal-title":"J Chromatogr B"},{"key":"2845_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/23312009.2016.1152784","volume":"2","author":"SD Bukkitgar","year":"2016","unstructured":"Bukkitgar SD, Shetti NP. Electrochemical oxidation of loop diuretic furosemide in aqueous acid medium and its analytical application. Cogent Chem. 2016;2:1\u201310.","journal-title":"Cogent Chem"},{"key":"2845_CR35","doi-asserted-by":"crossref","unstructured":"Silva EF, Tanaka AA, Fernandes RN, Alejandro R, Munoz A, da Silva IS. Batch injection analysis with electrochemical detection for the simultaneous determination of the diuretics furosemide and hydrochlorothiazide in synthetic urine and pharmaceutical samples. Microchem J. 2020;In Press.","DOI":"10.1016\/j.microc.2020.105027"}],"container-title":["Analytical and Bioanalytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-020-02845-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00216-020-02845-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-020-02845-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T23:24:17Z","timestamp":1627687457000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00216-020-02845-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,31]]},"references-count":35,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["2845"],"URL":"https:\/\/doi.org\/10.1007\/s00216-020-02845-9","relation":{},"ISSN":["1618-2642","1618-2650"],"issn-type":[{"value":"1618-2642","type":"print"},{"value":"1618-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,31]]},"assertion":[{"value":"10 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 July 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 July 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}