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Following this fact, an improvement for isotope dilution ICP-MS using the new instrumentation has been reported. This study aimed at investigating whether this improvement also meets the requirements of species-specific isotope dilution using GC\/ICP-MS, where short transient signals are recorded. The results of the analysis of monomethylmercury (MMHg) of a sediment reference material show that isotope ratio precision of ICP-MS instruments equipped with quadrupole, sector-field, and time-of-flight mass analyzers is similar within a broad range of peak signal-to-noise ratio when analyzing one isotopic system. The procedural limit of quantification (LOQ) for MMHg, expressed as mass fraction of Hg being present as MMHg, <jats:italic>w<\/jats:italic>(Hg)<jats:sub>MMHg<\/jats:sub>, was similar as well for all investigated instruments and ranged between 0.003 and 0.016 \u03bcg\/kg. Due to the simultaneous detection capability, the ICP-ToF-MS might, however, be more favorable when several isotopic systems are analyzed within one measurement. In a case study, the GC\/ICP-ToF-MS coupling was applied for analysis of MMHg in sediments of Finow Canal, a historic German canal heavily polluted with mercury. Mass fractions between 0.180 and 41 \u03bcg\/kg (<jats:italic>w<\/jats:italic>(Hg)<jats:sub>MMHg<\/jats:sub>) for MMHg, and 0.056 and 126 mg\/kg (<jats:italic>w<\/jats:italic>(Hg)<jats:sub>total<\/jats:sub>) for total mercury were found in sediment samples taken from the canal upstream and downstream of a former chemical plant.<\/jats:p>\n                <jats:p><jats:bold>Graphical abstract<\/jats:bold><\/jats:p>","DOI":"10.1007\/s00216-021-03497-z","type":"journal-article","created":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T21:02:30Z","timestamp":1627074150000},"page":"5279-5289","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Species-specific isotope dilution analysis of monomethylmercury in sediment using GC\/ICP-ToF-MS and comparison with ICP-Q-MS and ICP-SF-MS"],"prefix":"10.1007","volume":"413","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5361-715X","authenticated-orcid":false,"given":"Sebastian","family":"Fa\u00dfbender","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7225-7396","authenticated-orcid":false,"given":"Marcus","family":"von der Au","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Koenig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Pelzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Piechotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0104-748X","authenticated-orcid":false,"given":"Jochen","family":"Vogl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8636-0765","authenticated-orcid":false,"given":"Bj\u00f6rn","family":"Meermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,7,23]]},"reference":[{"key":"3497_CR1","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s12647-010-0017-7","volume":"25","author":"J Vogl","year":"2010","unstructured":"Vogl J, Pritzkow W. 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