{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T13:31:38Z","timestamp":1754487098420,"version":"3.37.3"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T00:00:00Z","timestamp":1735171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T00:00:00Z","timestamp":1735171200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004837","name":"Spanish Ministry of Science and Innovation","doi-asserted-by":"crossref","award":["RYC2022-038060-I"],"award-info":[{"award-number":["RYC2022-038060-I"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"crossref"}]},{"name":"European Union\u2019s Horizon 2020 research and innovation programme","award":["101007653"],"award-info":[{"award-number":["101007653"]}]},{"name":"European Union\u2019s Horizon Europe research and innovation programme","award":["101086360"],"award-info":[{"award-number":["101086360"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anal Bioanal Chem"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1007\/s00216-024-05691-1","type":"journal-article","created":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T02:23:12Z","timestamp":1735179792000},"page":"771-783","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Identification of putative volatile biomarkers of canine leishmaniasis in dog\u2019s breath and hair employing a novel algorithm for automated chromatographic peak detection and matching"],"prefix":"10.1007","volume":"417","author":[{"given":"Raluca","family":"Suschinel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aylen Lisset","family":"Jaimes-Mogoll\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siong Fong","family":"Sim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woei","family":"Ting","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Mart\u00edn","family":"C\u00e1ceres-Tarazona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliana","family":"Alvarez-Valdez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milton","family":"Rosero-Moreano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Fethi","family":"Diouani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emira","family":"Chouihi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihai","family":"Brebu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Violeta","family":"Simion","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Angel","family":"Barasona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radu","family":"Ionescu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,12,26]]},"reference":[{"key":"5691_CR1","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.jchromb.2018.12.015","volume":"1105","author":"S Giannoukos","year":"2019","unstructured":"Giannoukos S, Agapiou A, Brki\u0107 B, Taylor S. Volatolomics: a broad area of experimentation. J Chromatogr B. 2019;1105:136\u201347.","journal-title":"J Chromatogr B"},{"key":"5691_CR2","doi-asserted-by":"publisher","first-page":"037562","DOI":"10.1149\/1945-7111\/ab67a6","volume":"167","author":"S Das","year":"2020","unstructured":"Das S, Pal M. Review\u2014non-invasive monitoring of human health by exhaled breath analysis: a comprehensive review. J Electrochem Soc. 2020;167:037562.","journal-title":"J Electrochem Soc"},{"key":"5691_CR3","doi-asserted-by":"publisher","first-page":"11036","DOI":"10.1002\/anie.201500153","volume":"54","author":"YY Broza","year":"2015","unstructured":"Broza YY, Mochalski P, Ruzsanyi V, Amann A, Haick H. Hybrid volatolomics and disease detection. Angew Chem Int Ed. 2015;54:11036\u201348.","journal-title":"Angew Chem Int Ed"},{"key":"5691_CR4","doi-asserted-by":"publisher","first-page":"4611","DOI":"10.1038\/srep04611","volume":"4","author":"YY Broza","year":"2014","unstructured":"Broza YY, Zuri L, Haick H. Combined volatolomics for monitoring of human body chemistry. Sci Rep. 2014;4:4611.","journal-title":"Sci Rep"},{"key":"5691_CR5","doi-asserted-by":"publisher","first-page":"8185","DOI":"10.1007\/s12274-022-4459-3","volume":"15","author":"W Hu","year":"2022","unstructured":"Hu W, Wu W, Jian Y, Haick H, Zhang G, Qian Y, et al. Volatolomics in healthcare and its advanced detection technology. Nano Res. 2022;15:8185\u2013213.","journal-title":"Nano Res"},{"key":"5691_CR6","doi-asserted-by":"publisher","first-page":"2000397","DOI":"10.1002\/adbi.202000397","volume":"5","author":"AL Jaimes-Mogoll\u00f3n","year":"2021","unstructured":"Jaimes-Mogoll\u00f3n AL, Welearegay TG, Salumets A, Ionescu R. Review on volatolomic studies as a Frontier approach in animal research. Adv Biol. 2021;5:2000397.","journal-title":"Adv Biol"},{"key":"5691_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jchromb.2017.06.044","volume":"1061","author":"CJ Holderman","year":"2017","unstructured":"Holderman CJ, Kaufman PE, Booth MM, Bernier UR. Novel collection method for volatile organic compounds (VOCs) from dogs. J Chromatogr B. 2017;1061:1\u20134.","journal-title":"J Chromatogr B"},{"key":"5691_CR8","doi-asserted-by":"publisher","first-page":"6691","DOI":"10.1007\/s00216-014-8103-2","volume":"406","author":"JT Magalh\u00e3es-Junior","year":"2014","unstructured":"Magalh\u00e3es-Junior JT, Mesquita PRR, dos Santos Oliveira WF, Oliveira FS, Franke CR, de Medeiros RF, et al. Identification of biomarkers in the hair of dogs: new diagnostic possibilities in the study and control of visceral leishmaniasis. Anal Bioanal Chem. 2014;406:6691\u2013700.","journal-title":"Anal Bioanal Chem"},{"key":"5691_CR9","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1016\/j.jchromb.2008.09.028","volume":"875","author":"LS de Oliveira","year":"2008","unstructured":"de Oliveira LS, de M Rodrigues F, de Oliveira FS, Mesquita PRR, Leal DC, Alc\u00e2ntara AC, et al. Headspace solid phase microextraction\/gas chromatography\u2013mass spectrometry combined to chemometric analysis for volatile organic compounds determination in canine hair: a new tool to detect dog contamination by visceral leishmaniasis. J Chromatogr B. 2008;875:392\u20138.","journal-title":"J Chromatogr B"},{"key":"5691_CR10","doi-asserted-by":"publisher","first-page":"750","DOI":"10.12688\/f1000research.11120.1","volume":"6","author":"R Arenas","year":"2017","unstructured":"Arenas R, Torres-Guerrero E, Quintanilla-Cedillo MR, Ruiz-Esmenjaud J. Leishmaniasis: a review. F1000Res. 2017;6:750.","journal-title":"F1000Res"},{"key":"5691_CR11","doi-asserted-by":"publisher","first-page":"124","DOI":"10.4103\/0974-777X.62863","volume":"2","author":"A Clem","year":"2010","unstructured":"Clem A. A current perspective on leishmaniasis. J Glob Infect Dis. 2010;2:124\u20136.","journal-title":"J Glob Infect Dis"},{"key":"5691_CR12","first-page":"379","volume":"58","author":"LA Giraldo-Mart\u00ednez","year":"2022","unstructured":"Giraldo-Mart\u00ednez LA, Petano-Duque JM, Uribe-Garc\u00eda HF, Chac\u00f3n-Novoa RA, Guzm\u00e1n-Barrag\u00e1n BL, Rond\u00f3n-Barrag\u00e1n I. High prevalence of Leishmania spp. in dogs from Central West Colombia. Vet Ital. 2022;58:379\u201389.","journal-title":"Vet Ital"},{"key":"5691_CR13","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.actatropica.2011.03.001","volume":"118","author":"K A\u00eft-Oudhia","year":"2011","unstructured":"A\u00eft-Oudhia K, Harrat Z, Benikhlef R, Dedet JP, Pratlong F. Canine Leishmania infantum enzymatic polymorphism: a review including 1023 strains of the Mediterranean area, with special reference to Algeria. Acta Trop. 2011;118:80\u20136.","journal-title":"Acta Trop"},{"key":"5691_CR14","unstructured":"Un ni\u00f1o muerto por brote de Leishmaniasis visceral en Neiva. La Naci\u00f3n 2017 [Internet]. Available from: https:\/\/www.lanacion.com.co\/un-nino-muerto-por-brote-de-leishmaniasis-visceral-en-neiva\/.\u00a0Accessed 30 Aug 2024."},{"key":"5691_CR15","doi-asserted-by":"publisher","first-page":"1143939","DOI":"10.3389\/fpubh.2023.1143939","volume":"11","author":"R Suschinel","year":"2023","unstructured":"Suschinel R, Jaimes-Mogoll\u00f3n AL, Guti\u00e9rrez-Mar\u00edn R, Pe\u00f1a-Cort\u00e9s LC, Mendoza-Ibarra JA, Fl\u00f3rez-G\u00e9lvez J, et al. Challenges during the realization of an international research project on leishmaniasis in Colombia. Front Public Health. 2023;11:1143939.","journal-title":"Front Public Health"},{"key":"5691_CR16","doi-asserted-by":"publisher","first-page":"271970","DOI":"10.1155\/2014\/271970","volume":"2014","author":"SF Sim","year":"2014","unstructured":"Sim SF, Lee TZE, Mohd Irwan Lu NAL, Samling B. Synchronized analysis of FTIR spectra and GCMS chromatograms for evaluation of the thermally degraded vegetable oils. J Anal Methods Chem. 2014;2014:271970.","journal-title":"J Anal Methods Chem"},{"key":"5691_CR17","doi-asserted-by":"publisher","first-page":"3631","DOI":"10.1021\/ac034173t","volume":"75","author":"PHC Eilers","year":"2003","unstructured":"Eilers PHC. A perfect smoother. Anal Chem. 2003;75:3631\u20136.","journal-title":"Anal Chem"},{"key":"5691_CR18","doi-asserted-by":"publisher","first-page":"1590","DOI":"10.3390\/pharmaceutics14081590","volume":"14","author":"S Jain","year":"2022","unstructured":"Jain S, Sahu U, Kumar A, Khare P. Metabolic pathways of Leishmania parasite: source of pertinent drug targets and potent drug candidates. Pharmaceutics. 2022;14:1590.","journal-title":"Pharmaceutics"},{"key":"5691_CR19","doi-asserted-by":"publisher","first-page":"632512","DOI":"10.3389\/fimmu.2021.632512","volume":"12","author":"M Ohms","year":"2021","unstructured":"Ohms M, Ferreira C, Busch H, Wohlers I, Guerra de Souza AC, Silvestre R, et al. Enhanced glycolysis is required for antileishmanial functions of neutrophils upon infection with Leishmania donovani. Front Immunol. 2021;12:632512.","journal-title":"Front Immunol"},{"key":"5691_CR20","unstructured":"Stouten H. DECOS and SCG basis for an occupational standard isopropyl acetate. Arbete och H\u00e4lsa 1997;11. https:\/\/gupea.ub.gu.se\/bitstream\/handle\/2077\/4164\/ah1997_11.pdf?sequence=1."},{"key":"5691_CR21","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1042\/bj0560182","volume":"56","author":"S Crowther","year":"1954","unstructured":"Crowther S, Fulton JD, Joyner LP. The metabolism of Leishtmania donovani in culture. Biochem J. 1954;56:182\u20135.","journal-title":"Biochem J"},{"key":"5691_CR22","first-page":"269","volume":"10","author":"L Monzote","year":"2016","unstructured":"Monzote L, Perera C\u00f3rdova WH, Garc\u00eda M, Pi\u00f1\u00f3n A, Setzer WN. In-vitro and in-vivo activities of phenolic compounds against cutaneous leishmaniasis. Rec Nat Prod. 2016;10:269\u201376.","journal-title":"Rec Nat Prod"},{"key":"5691_CR23","doi-asserted-by":"publisher","first-page":"10743","DOI":"10.15446\/rfnam.v77n2.109468","volume":"77","author":"PT Quyen","year":"2024","unstructured":"Quyen PT, Quoc LPT. Chemical composition and biological evaluation of tea tree (Melaleuca alternifolia L.) leaves essential oils. Rev Fac Nac Agron Medellin. 2024;77:10743\u201350.","journal-title":"Rev Fac Nac Agron Medellin"},{"key":"5691_CR24","first-page":"552","volume":"32","author":"CA Pinilla","year":"2021","unstructured":"Pinilla CA, L\u00f3pez \u00c1M, G\u00e1lvez AF, Corpas EJ, Rosero-Moreano M, Stashenko EE. Evaluation of antibacterial activity, chromatographic analysis for rutin and quercetin quantification using HPLC-UV-vis from the hydro-alcoholic extract obtained from bidens pilosa linn\u00e9. J Braz Chem Soc. 2021;32:552\u201363.","journal-title":"J Braz Chem Soc"},{"key":"5691_CR25","doi-asserted-by":"publisher","first-page":"340215","DOI":"10.1155\/2013\/340215","volume":"2013","author":"AP Bartolome","year":"2013","unstructured":"Bartolome AP, Villase\u00f1or IM, Yang WC. Bidens pilosa L. (Asteraceae): botanical properties, traditional uses, phytochemistry, and pharmacology. Evid Based Complement Alternat Med. 2013;2013:340215.","journal-title":"Evid Based Complement Alternat Med"},{"key":"5691_CR26","doi-asserted-by":"publisher","first-page":"e0009062","DOI":"10.1371\/journal.pntd.0009062","volume":"15","author":"IB Hassaballa","year":"2021","unstructured":"Hassaballa IB, Torto B, Sole CL, Tchouassi DP. Exploring the influence of different habitats and their volatile chemistry in modulating sand fly population structure in a leishmaniasis endemic Foci, Kenya. PLoS Negl Trop Dis. 2021;15:e0009062.","journal-title":"PLoS Negl Trop Dis"},{"key":"5691_CR27","doi-asserted-by":"publisher","first-page":"e1700324","DOI":"10.1002\/cbdv.201700324","volume":"14","author":"M Morimoto","year":"2017","unstructured":"Morimoto M, Cantrell CL, Khan S, Tekwani BL, Duke SO. Antimalarial and antileishmanial activities of phytophenolics and their synthetic analogues. Chem Biodivers. 2017;14:e1700324.","journal-title":"Chem Biodivers"},{"key":"5691_CR28","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1590\/S0102-695X2012005000086","volume":"22","author":"H Paes-Gon\u00e7alves","year":"2012","unstructured":"Paes-Gon\u00e7alves H, Facundo VA, Santos DMF, Silva AGC, Ballico LJ, Lima DKS, et al. The leishmanicidal activity of a cyclopentenedione derivative isolated from the roots of a native Amazonian pepper (Piper carniconnectivum). Brazilian Journal of Pharmacognosy. 2012;22:1018\u201323.","journal-title":"Brazilian Journal of Pharmacognosy"},{"key":"5691_CR29","doi-asserted-by":"publisher","first-page":"4702","DOI":"10.3390\/ijms24054702","volume":"24","author":"M Leroux","year":"2023","unstructured":"Leroux M, Luquain-Costaz C, Lawton P, Azzouz-Maache S, Delton I. Fatty acid composition and metabolism in Leishmania parasite species: potential biomarkers or drug targets for leishmaniasis? Int J Mol Sci. 2023;24:4702.","journal-title":"Int J Mol Sci"},{"key":"5691_CR30","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1590\/S0074-02762010000100013","volume":"105","author":"W Mayrink","year":"2010","unstructured":"Mayrink W, Alberto Pereira Tavares C, Barbosa de Deus R, Barros Pinheiro M, Mara Pinto Dab\u00e9s Guimar\u00e3es T, Monteiro de Andrade H, et al. Comparative evaluation of phenol and thimerosal as preservatives for a candidate vaccine against American cutaneous leishmaniasis. Mem Inst Oswaldo Cruz. 2010;105:86\u201391.","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"5691_CR31","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1016\/j.bbapap.2017.12.002","volume":"1866","author":"B Patel","year":"2018","unstructured":"Patel B, Patel D, Parmar K, Chauhan R, Singh DD, Pappachan AL. donovani XPRT: Molecular characterization and evaluation of inhibitors. Biochim Biophys Acta Proteins Proteom. 2018;1866:426\u201341.","journal-title":"Biochim Biophys Acta Proteins Proteom"},{"key":"5691_CR32","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1136\/thorax-2022-219708","volume":"78","author":"A Peel","year":"2023","unstructured":"Peel A, Wang R, Ahmed W, White I, Wilkinson M, Loke YK, et al. Changes in exhaled volatile organic compounds following indirect bronchial challenge in suspected asthma. Thorax. 2023;78:966\u201373.","journal-title":"Thorax"},{"key":"5691_CR33","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1002\/bmc.1410","volume":"24","author":"ZY Guo","year":"2010","unstructured":"Guo ZY, Gai PP, Duan J, Zhai JX, Zhao SS, Wang S, et al. Simultaneous determination of phthalates and adipates in human serum using gas chromatography-mass spectrometry with solid-phase extraction. Biomed Chromatogr. 2010;24:1094\u20139.","journal-title":"Biomed Chromatogr"}],"container-title":["Analytical and Bioanalytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-024-05691-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00216-024-05691-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-024-05691-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T05:32:10Z","timestamp":1737955930000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00216-024-05691-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,26]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["5691"],"URL":"https:\/\/doi.org\/10.1007\/s00216-024-05691-1","relation":{},"ISSN":["1618-2642","1618-2650"],"issn-type":[{"type":"print","value":"1618-2642"},{"type":"electronic","value":"1618-2650"}],"subject":[],"published":{"date-parts":[[2024,12,26]]},"assertion":[{"value":"30 July 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 November 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 December 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval for this study was obtained from the Committee for Ethics and Environmental Impact in Research of University of Pamplona, Colombia (Approval Certificate No. 002 from April 14, 2021).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Animal welfare statement"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}