{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T03:06:26Z","timestamp":1789787186432,"version":"4.0.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"19","license":[{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"National Key Research and Development Program of China","award":["2023YFF1105004"],"award-info":[{"award-number":["2023YFF1105004"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anal Bioanal Chem"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1007\/s00216-025-05952-7","type":"journal-article","created":{"date-parts":[[2025,6,15]],"date-time":"2025-06-15T22:44:21Z","timestamp":1750027461000},"page":"4373-4382","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Development of a reference material for simultaneous quantitative determination of multiple veterinary drug residues"],"prefix":"10.1007","volume":"417","author":[{"given":"Cheng","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengping","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunhua","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianhua","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,16]]},"reference":[{"issue":"18","key":"5952_CR1","doi-asserted-by":"publisher","first-page":"5649","DOI":"10.1073\/pnas.1503141112","volume":"112","author":"TP Van Boeckel","year":"2015","unstructured":"Van Boeckel TP, Brower C, Gilbert M, Grenfell BT, Levin SA, Robinson TP, Teillant A, Laxminarayan R. Global trends in antimicrobial use in food animals. Proc Natl Acad Sci U S A. 2015;112(18):5649\u201354. https:\/\/doi.org\/10.1073\/pnas.1503141112.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"5952_CR2","doi-asserted-by":"publisher","first-page":"136168","DOI":"10.1016\/j.foodchem.2023.136168","volume":"421","author":"Z He","year":"2023","unstructured":"He Z, Shi X, Guo Y, Guan F, Gao P, Tang Y, Liu S, Zhu Y, Xie K, Chen H. Simultaneous quantitative determination of residues of abamectin, ivermectin, albendazole and its three metabolites in beef and chicken by HPLC-PDA. Food Chem. 2023;421:136168. https:\/\/doi.org\/10.1016\/j.foodchem.2023.136168.","journal-title":"Food Chem"},{"issue":"11","key":"5952_CR3","doi-asserted-by":"publisher","first-page":"1629","DOI":"10.3390\/foods13111629","volume":"13","author":"HO Khalifa","year":"2024","unstructured":"Khalifa HO, Shikoray L, Mohamed MI, Habib I, Matsumoto T. Veterinary drug residues in the food chain as an emerging public health threat: sources, analytical methods, health impacts, and preventive measures. Foods. 2024;13(11):1629. https:\/\/doi.org\/10.3390\/foods13111629.","journal-title":"Foods"},{"issue":"11","key":"5952_CR4","doi-asserted-by":"publisher","first-page":"e21160","DOI":"10.1016\/j.heliyon.2023.e21160","volume":"9","author":"JEV Sin","year":"2023","unstructured":"Sin JEV, Shen P, Teo GS, Neo LP, Huang L, Chua P, Tan MW, Wu Y, Li A, Er JC, Chan SH. Surveillance of veterinary drug residues in food commonly consumed in Singapore and assessment of dietary exposure. Heliyon. 2023;9(11):e21160. https:\/\/doi.org\/10.1016\/j.heliyon.2023.e21160.","journal-title":"Heliyon"},{"issue":"15","key":"5952_CR5","doi-asserted-by":"publisher","first-page":"286A","DOI":"10.1016\/j.heliyon.2023.e21160","volume":"37","author":"ABA Boxall","year":"2003","unstructured":"Boxall ABA, Kolpin DW, Halling-S\u00f8rensen B, Tolls J. Are veterinary medicines causing environmental risks? Environ Sci Technol. 2003;37(15):286A-294A. https:\/\/doi.org\/10.1016\/j.heliyon.2023.e21160.","journal-title":"Environ Sci Technol"},{"issue":"12","key":"5952_CR6","doi-asserted-by":"publisher","first-page":"5534","DOI":"10.1021\/acs.est.4c00993","volume":"58","author":"S Li","year":"2024","unstructured":"Li S, Zhu Y, Zhong G, Huang Y, Jones KC. Comprehensive assessment of environmental emissions, fate, and risks of veterinary antibiotics in China: an environmental fate modeling approach. Environ Sci Technol. 2024;58(12):5534\u201347. https:\/\/doi.org\/10.1021\/acs.est.4c00993.","journal-title":"Environ Sci Technol"},{"issue":"10","key":"5952_CR7","doi-asserted-by":"publisher","first-page":"1430","DOI":"10.3390\/foods11101430","volume":"11","author":"OM Ghimpe\u021beanu","year":"2022","unstructured":"Ghimpe\u021beanu OM, Pogurschi EN, Popa DC, Dragomir N, Dr\u0103gotoiu T, Mihai OD, Petcu CD. Antibiotic Use in Livestock and Residues in Food-A Public Health Threat: A Review. Foods. 2022;11(10):1430. https:\/\/doi.org\/10.3390\/foods11101430.","journal-title":"Foods"},{"issue":"11","key":"5952_CR8","doi-asserted-by":"publisher","first-page":"6152","DOI":"10.1002\/fsn3.2568","volume":"9","author":"Y Zhang","year":"2021","unstructured":"Zhang Y, Lu J, Yan Y, Liu J, Wang M. Antibiotic residues in cattle and sheep meat and human exposure assessment in southern Xinjiang. China Food Sci Nutr. 2021;9(11):6152\u201361. https:\/\/doi.org\/10.1002\/fsn3.2568.","journal-title":"China Food Sci Nutr"},{"issue":"8","key":"5952_CR9","doi-asserted-by":"publisher","first-page":"2258","DOI":"10.3390\/ani11082258","volume":"11","author":"HO Khalifa","year":"2021","unstructured":"Khalifa HO, Oreiby A, Abd El-Hafeez AA, Abd El Latif A, Okanda T, Kato Y, Matsumoto T. High \u03b2-Lactam and quinolone resistance of Enterobacteriaceae from the respiratory tract of Sheep and goat with respiratory disease. Animals (Basel). 2021;11(8):2258. https:\/\/doi.org\/10.3390\/ani11082258.","journal-title":"Animals (Basel)"},{"issue":"1","key":"5952_CR10","doi-asserted-by":"publisher","first-page":"e01890","DOI":"10.1128\/AAC.01890-20","volume":"65","author":"HO Khalifa","year":"2020","unstructured":"Khalifa HO, Oreiby AF, Abd El-Hafeez AA, Okanda T, Haque A, Anwar KS, Tanaka M, Miyako K, Tsuji S, Kato Y, Matsumoto T. First report of multidrug-resistant carbapenemase-producing bacteria coharboring mcr-9 associated with respiratory disease complex in pets: potential of animal-human transmission. Antimicrob Agents Chemother. 2020;65(1):e01890-e1920. https:\/\/doi.org\/10.1128\/AAC.01890-20.","journal-title":"Antimicrob Agents Chemother"},{"key":"5952_CR11","doi-asserted-by":"publisher","first-page":"2434","DOI":"10.1007\/s12161-016-0436-3","volume":"9","author":"L An","year":"2016","unstructured":"An L, Wang Y, Pan Y, Tao Y, Chen D, Liu Z, Yang W, Peng D, Yuan Z. Development and validation of a sensitive indirect competitive enzyme-linked immunosorbent assay for the screening of florfenicol and thiamphenicol in edible animal tissue and feed. Food Anal Methods. 2016;9:2434\u201343. https:\/\/doi.org\/10.1007\/s12161-016-0436-3.","journal-title":"Food Anal Methods"},{"issue":"2","key":"5952_CR12","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1080\/10408347.2021.1964342","volume":"53","author":"JR Matos","year":"2023","unstructured":"Matos JR, Santos SS, Silva RAI, Souto RB. Analytical methods for the quality control of veterinary antimicrobials medicines. Crit Rev Anal Chem. 2023;53(2):384\u201395. https:\/\/doi.org\/10.1080\/10408347.2021.1964342.","journal-title":"Crit Rev Anal Chem"},{"key":"5952_CR13","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.jpha.2011.09.007","volume":"2","author":"H Yu","year":"2012","unstructured":"Yu H, Mu H, Hu YM. Determination of fluoroquinolones, sulfonamides, and tetracyclines multiresidues simultaneously in porcine tissue by MSPD and HPLC-DAD. J Pharm Anal. 2012;2:76\u201381. https:\/\/doi.org\/10.1016\/j.jpha.2011.09.007.","journal-title":"J Pharm Anal"},{"key":"5952_CR14","doi-asserted-by":"publisher","unstructured":"Caban M, Hali\u0144ski \u0141P, Kumirska J, Stepnowski P. Gas chromatography applied to the analysis of drug and veterinary drug residues in food, environmental, and biological samples. In determination of target xenobiotics and unknown compound residues in food, environmental, and biological samples. Sherma J, Tuzimski T, Eds, CRC Press: Boca Raton, FL, USA, 2018; p.133\u2013166. https:\/\/doi.org\/10.1201\/9780429446900-9.","DOI":"10.1201\/9780429446900-9"},{"issue":"5","key":"5952_CR15","doi-asserted-by":"publisher","first-page":"651","DOI":"10.3390\/foods9050651","volume":"9","author":"B Wang","year":"2020","unstructured":"Wang B, Wang Y, Xie X, Diao Z, Xie K, Zhang G, Zhang T, Dai G. Quantitative analysis of spectinomycin and lincomycin in poultry eggs by accelerated solvent extraction coupled with gas chromatography tandem mass spectrometry. Foods. 2020;9(5):651. https:\/\/doi.org\/10.3390\/foods9050651.","journal-title":"Foods"},{"key":"5952_CR16","doi-asserted-by":"publisher","first-page":"138834","DOI":"10.1016\/j.foodchem.2024.138834","volume":"449","author":"L Kenjeric","year":"2024","unstructured":"Kenjeric L, Sulyok M, Malachova A, Greer B, Kolawole O, Quinn B, Elliott CT, Krska R. Extention and interlaboratory comparison of an LC-MS\/MS multi-class method for the determination of 15 different classes of veterinary drug residues in milk and poultry feed. Food Chem. 2024;449:138834. https:\/\/doi.org\/10.1016\/j.foodchem.2024.138834.","journal-title":"Food Chem"},{"issue":"18\u201319","key":"5952_CR17","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.1002\/elps.202000160","volume":"41","author":"TA Donegatti","year":"2020","unstructured":"Donegatti TA, Lobato A, Duek EAR, Moreira Gon\u00e7alves L, Alves PE. Derivatization-free determination of aminoglycosides by CZE-UV in pharmaceutical formulations. Electrophoresis. 2020;41(18\u201319):1576\u201383. https:\/\/doi.org\/10.1002\/elps.202000160.","journal-title":"Electrophoresis"},{"key":"5952_CR18","doi-asserted-by":"publisher","first-page":"e1810","DOI":"10.1002\/elps.202000160","volume":"46","author":"S Zhao","year":"2018","unstructured":"Zhao S, Wang H, Li K, Zhang J, Wang X, Guo G. Fast determination of residual sulfonamides in milk by in-tube solid-phase microextraction coupled with capillary electrophoresis-laser induced fluorescence. Chin J Anal Chem. 2018;46:e1810\u20136. https:\/\/doi.org\/10.1002\/elps.202000160.","journal-title":"Chin J Anal Chem"},{"issue":"23","key":"5952_CR19","doi-asserted-by":"publisher","first-page":"2242","DOI":"10.2174\/1568026623666230718163613","volume":"23","author":"N Amin","year":"2023","unstructured":"Amin N, Almasi A, Ozer T, Henry CS, Hosseinzadeh L, Keshavarzi Z. Recent advances of optical biosensors in veterinary medicine: moving towards the point of care applications. Curr Top Med Chem. 2023;23(23):2242\u201365. https:\/\/doi.org\/10.2174\/1568026623666230718163613.","journal-title":"Curr Top Med Chem"},{"issue":"6","key":"5952_CR20","doi-asserted-by":"publisher","first-page":"433","DOI":"10.3390\/bios12060433","volume":"12","author":"M Calero","year":"2022","unstructured":"Calero M, Fern\u00e1ndez R, Garc\u00eda M, Juan-Borr\u00e1s M, Escriche I, Arnau A, Montoya \u00c1, Jim\u00e9nez Y. High Fundamental Frequency (HFF) monolithic quartz crystal microbalance with Dissipation array for the simultaneous detection of pesticides and antibiotics in complex food. Biosensors (Basel). 2022;12(6):433. https:\/\/doi.org\/10.3390\/bios12060433.","journal-title":"Biosensors (Basel)"},{"key":"5952_CR21","unstructured":"Validation of analytical procedures: text and methodology, european medicines agency Q2. Westferry Circus, Canary Wharf, London. 2023."},{"key":"5952_CR22","doi-asserted-by":"publisher","DOI":"10.1002\/dta.3843","author":"MC Monti","year":"2024","unstructured":"Monti MC, Bauer M, Koch K, Scheurer E, Schlotterbeck G. Evaluation of ATR-FTIR, HPLC-DAD, GC-MS, and GC-IR for the analysis of 145 street drug samples from drug checking services. Drug Test Anal. 2024. https:\/\/doi.org\/10.1002\/dta.3843.","journal-title":"Drug Test Anal"},{"key":"5952_CR23","unstructured":"Iso, 33405. Reference materials-approaches for characterization and assessment of and stability. Geneva: ISO; 2024."},{"issue":"3","key":"5952_CR24","doi-asserted-by":"publisher","first-page":"126","DOI":"10.3390\/vetsci9030126","volume":"9","author":"X Ma","year":"2022","unstructured":"Ma X, Chen L, Yin L, Li Y, Yang X, Yang Z, Li G, Shan H. Risk analysis of 24 residual antibiotics in poultry eggs in Shandong, China (2018\u20132020). Vet Sci. 2022;9(3):126. https:\/\/doi.org\/10.3390\/vetsci9030126.","journal-title":"Vet Sci"},{"key":"5952_CR25","doi-asserted-by":"publisher","first-page":"131733","DOI":"10.1016\/j.foodchem.2021.131733","volume":"374","author":"Y Yang","year":"2022","unstructured":"Yang Y, Lin G, Liu L, Lin T. Rapid determination of multi-antibiotic residues in honey based on modified QuEChERS method coupled with UPLC-MS\/MS. Food Chem. 2022;374:131733. https:\/\/doi.org\/10.1016\/j.foodchem.2021.131733.","journal-title":"Food Chem"},{"key":"5952_CR26","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1016\/j.fct.2019.01.033","volume":"125","author":"M Bacanl\u0131","year":"2019","unstructured":"Bacanl\u0131 M, Ba\u015faran N. Importance of antibiotic residues in animal food. Food Chem Toxicol. 2019;125:462\u20136. https:\/\/doi.org\/10.1016\/j.fct.2019.01.033.","journal-title":"Food Chem Toxicol"},{"issue":"5","key":"5952_CR27","doi-asserted-by":"publisher","first-page":"534","DOI":"10.3390\/antibiotics10050534","volume":"10","author":"FM Treiber","year":"2021","unstructured":"Treiber FM, Beranek-Knauer H. Antimicrobial residues in food from animal origin-a review of the literature focusing on products collected in stores and markets worldwide. Antibiotics (Basel). 2021;10(5):534. https:\/\/doi.org\/10.3390\/antibiotics10050534.","journal-title":"Antibiotics (Basel)"},{"issue":"5","key":"5952_CR28","doi-asserted-by":"publisher","first-page":"687","DOI":"10.5851\/kosfa.2019.e65","volume":"39","author":"MS Rana","year":"2019","unstructured":"Rana MS, Lee SY, Kang HJ, Hur SJ. Reducing veterinary drug residues in animal products: a review. Food Sci Anim Resour. 2019;39(5):687\u2013703. https:\/\/doi.org\/10.5851\/kosfa.2019.e65.","journal-title":"Food Sci Anim Resour"},{"issue":"39","key":"5952_CR29","doi-asserted-by":"publisher","first-page":"12681","DOI":"10.1021\/acs.jafc.2c03833","volume":"70","author":"P Sang","year":"2022","unstructured":"Sang P, Lu G, Yu D, Song X, Guo Y, Xie Y, Yao W, Qian H, Hu Z. Simultaneous determination of antibiotics, mycotoxins, and hormones in milk by an 8\u201317 DNAzyme-based enzyme-linked immunosorbent assay. J Agric Food Chem. 2022;70(39):12681\u20138. https:\/\/doi.org\/10.1021\/acs.jafc.2c03833.","journal-title":"J Agric Food Chem"},{"issue":"11","key":"5952_CR30","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1631\/jzus.B1100076","volume":"12","author":"H Zhang","year":"2011","unstructured":"Zhang H, Jiang J, Wang Z, Chang X, Liu X, Wang S, Zhao K, Chen J. Development of an indirect competitive ELISA for simultaneous detection of enrofloxacin and ciprofloxacin. J Zhejiang Univ Sci B. 2011;12(11):884\u201391. https:\/\/doi.org\/10.1631\/jzus.B1100076.","journal-title":"J Zhejiang Univ Sci B"},{"key":"5952_CR31","doi-asserted-by":"publisher","first-page":"102397","DOI":"10.1016\/j.fochx.2025.102397","volume":"27","author":"Z Chen","year":"2025","unstructured":"Chen Z, Daka Z, Yao L, Dong J, Zhang Y, Li P, Zhang K, Ji S. Recent progress in the application of chromatography-coupled mass-spectrometry in the analysis of contaminants in food products. Food Chem X. 2025;27:102397. https:\/\/doi.org\/10.1016\/j.fochx.2025.102397.","journal-title":"Food Chem X"},{"issue":"4","key":"5952_CR32","doi-asserted-by":"publisher","first-page":"873","DOI":"10.5851\/kosfa.2024.e24","volume":"44","author":"D Park","year":"2024","unstructured":"Park D, Choi YS, Kim JY, Choi JD, Moon GI. Determination of Flunixin and 5-Hydroxy Flunixin Residues in livestock and fishery products using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS\/MS). Food Sci Anim Resour. 2024;44(4):873\u201384. https:\/\/doi.org\/10.5851\/kosfa.2024.e24.","journal-title":"Food Sci Anim Resour"}],"container-title":["Analytical and Bioanalytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-025-05952-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00216-025-05952-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-025-05952-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T08:35:44Z","timestamp":1753173344000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00216-025-05952-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,16]]},"references-count":32,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["5952"],"URL":"https:\/\/doi.org\/10.1007\/s00216-025-05952-7","relation":{},"ISSN":["1618-2642","1618-2650"],"issn-type":[{"value":"1618-2642","type":"print"},{"value":"1618-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,16]]},"assertion":[{"value":"21 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2025","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 May 2025","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 June 2025","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}