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Approval for the study was obtained from the ethical committee at\n                      Hospital Universitario Central de Asturias\n                      (HUCA) (No 275\/19). All samples were collected at\n                      Hospital Universitario Central de Asturias\n                      and stored at\u2009\u2212\u200980\u00a0\u00b0C. All patient codes have been removed in this publication.\n                      \n                        Sample group II\u2014Fecal and plasma samples\n                      \n                      : Fecal and plasma samples were obtained from high-risk pancreatic cancer patients in accordance with the World Medical Association Declaration of Helsinki, and all patients gave written informed consent. Approval for the study was obtained from the ethical committee at Karolinska University Hospital (ethical approval number: Dnr2017\/290\u201331). Plasma and fecal samples were collected using routine clinical collection protocols at Karolinska University Hospital, and all patient codes have been removed in this publication. All samples were stored at\u2009\u2212\u200980\u00a0\u00b0C.","order":1,"name":"Ethics","label":"Ethics approval and source of biological material","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}