{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T08:26:51Z","timestamp":1786609611646,"version":"build-2736575974"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"17","license":[{"start":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T00:00:00Z","timestamp":1781913600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T00:00:00Z","timestamp":1781913600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R01GM087964"],"award-info":[{"award-number":["R01GM087964"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anal Bioanal Chem"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1007\/s00216-026-06630-y","type":"journal-article","created":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T09:44:31Z","timestamp":1781948671000},"page":"5577-5585","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Differentiation of wild-type and PAP1-overexpressing tobacco by volatile organic compound profiling using TP-SESI mass spectrometry"],"prefix":"10.1007","volume":"418","author":[{"given":"Sarah M.","family":"Ashbacher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"De-Yu","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Muddiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,20]]},"reference":[{"issue":"4","key":"6630_CR1","doi-asserted-by":"publisher","first-page":"1893","DOI":"10.1104\/pp.104.049981","volume":"135","author":"N Dudareva","year":"2004","unstructured":"Dudareva N, Pichersky E, Gershenzon J. Biochemistry of plant volatiles. Plant Physiol. 2004;135(4):1893\u2013902. https:\/\/doi.org\/10.1104\/pp.104.049981.","journal-title":"Plant Physiol"},{"issue":"3","key":"6630_CR2","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.tplants.2009.12.006","volume":"15","author":"F Loreto","year":"2010","unstructured":"Loreto F, Schnitzler J-P. Abiotic stresses and induced BVOCs. Trends Plant Sci. 2010;15(3):154\u201366. https:\/\/doi.org\/10.1016\/j.tplants.2009.12.006.","journal-title":"Trends Plant Sci"},{"issue":"1","key":"6630_CR3","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1111\/nph.12145","volume":"198","author":"N Dudareva","year":"2013","unstructured":"Dudareva N, Klempien A, Muhlemann JK, Kaplan I. Biosynthesis, function and metabolic engineering of plant volatile organic compounds. New Phytol. 2013;198(1):16\u201332. https:\/\/doi.org\/10.1111\/nph.12145.","journal-title":"New Phytol"},{"key":"6630_CR4","doi-asserted-by":"publisher","unstructured":"Tholl, D. Biosynthesis and biological functions of terpenoids in plants. In Biotechnology of isoprenoids; Advances in biochemical engineering\/biotechnology, 2015; Vol. 148, pp 63\u2013106. https:\/\/doi.org\/10.1007\/10_2014_295.","DOI":"10.1007\/10_2014_295"},{"issue":"23","key":"6630_CR5","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21238956","volume":"21","author":"J Picazo-Aragon\u00e9s","year":"2020","unstructured":"Picazo-Aragon\u00e9s J, Terrab A, Balao F. Plant volatile organic compounds evolution: transcriptional regulation, epigenetics and polyploidy. Int J Mol Sci. 2020;21(23):8956. https:\/\/doi.org\/10.3390\/ijms21238956.","journal-title":"Int J Mol Sci"},{"issue":"19","key":"6630_CR6","doi-asserted-by":"publisher","DOI":"10.3390\/plants11192566","volume":"11","author":"J Midzi","year":"2022","unstructured":"Midzi J, Jeffery DW, Baumann U, Rogiers S, Tyerman SD, Pagay V. Stress-induced volatile emissions and signalling in inter-plant communication. Plants. 2022;11(19):2566. https:\/\/doi.org\/10.3390\/plants11192566.","journal-title":"Plants"},{"issue":"5","key":"6630_CR7","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1111\/tpj.14496","volume":"100","author":"H Bouwmeester","year":"2019","unstructured":"Bouwmeester H, Schuurink RC, Bleeker PM, Schiestl F. The role of volatiles in plant communication. Plant J. 2019;100(5):892\u2013907. https:\/\/doi.org\/10.1111\/tpj.14496.","journal-title":"Plant J"},{"key":"6630_CR8","doi-asserted-by":"publisher","DOI":"10.3389\/fhort.2024.1394041","author":"L Makhlouf","year":"2024","unstructured":"Makhlouf L, El Fakhouri K, Kemal SA, Aasfar A, Meftah Kadmiri I, El Bouhssini M. Advances in analytical techniques for assessing volatile organic compounds in pulse crops: a comprehensive review. Front Hortic. 2024. https:\/\/doi.org\/10.3389\/fhort.2024.1394041.","journal-title":"Front Hortic"},{"issue":"40","key":"6630_CR9","doi-asserted-by":"publisher","first-page":"22335","DOI":"10.1039\/C8RA01574K","volume":"8","author":"J-L Ren","year":"2018","unstructured":"Ren J-L, Zhang A-H, Kong L, Wang X-J. Advances in mass spectrometry-based metabolomics for investigation of metabolites. RSC Adv. 2018;8(40):22335\u201350. https:\/\/doi.org\/10.1039\/C8RA01574K.","journal-title":"RSC Adv"},{"issue":"4","key":"6630_CR10","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1111\/j.1365-313X.2005.02612.x","volume":"45","author":"D Tholl","year":"2006","unstructured":"Tholl D, Boland W, Hansel A, Loreto F, R\u00f6se USR, Schnitzler J. Practical approaches to plant volatile analysis. Plant J. 2006;45(4):540\u201360. https:\/\/doi.org\/10.1111\/j.1365-313X.2005.02612.x.","journal-title":"Plant J"},{"issue":"46","key":"6630_CR11","doi-asserted-by":"publisher","first-page":"12945","DOI":"10.1021\/acs.jafc.9b05339","volume":"67","author":"D Wu","year":"2019","unstructured":"Wu D, Cui M, Hao Y, Liu L, Zhou Y, Wang W, et al. In situ study of metabolic response of Arabidopsis thaliana leaves to salt stress by neutral desorption-extractive electrospray ionization mass spectrometry. J Agric Food Chem. 2019;67(46):12945\u201352. https:\/\/doi.org\/10.1021\/acs.jafc.9b05339.","journal-title":"J Agric Food Chem"},{"issue":"2","key":"6630_CR12","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1021\/ac9907235","volume":"72","author":"C Wu","year":"2000","unstructured":"Wu C, Siems WF, Hill HH. Secondary electrospray ionization ion mobility spectrometry\/mass spectrometry of illicit drugs. Anal Chem. 2000;72(2):396\u2013403. https:\/\/doi.org\/10.1021\/ac9907235.","journal-title":"Anal Chem"},{"issue":"10","key":"6630_CR13","doi-asserted-by":"publisher","first-page":"2741","DOI":"10.1021\/ac0354591","volume":"76","author":"M Tam","year":"2004","unstructured":"Tam M, Hill HH. Secondary electrospray ionization-ion mobility spectrometry for explosive vapor detection. Anal Chem. 2004;76(10):2741\u20137. https:\/\/doi.org\/10.1021\/ac0354591.","journal-title":"Anal Chem"},{"issue":"10","key":"6630_CR14","doi-asserted-by":"publisher","first-page":"1967","DOI":"10.1021\/jasms.2c00201","volume":"33","author":"J Kaeslin","year":"2022","unstructured":"Kaeslin J, W\u00fcthrich C, Giannoukos S, Zenobi R. How soft is secondary electrospray ionization? J Am Soc Mass Spectrom. 2022;33(10):1967\u201374. https:\/\/doi.org\/10.1021\/jasms.2c00201.","journal-title":"J Am Soc Mass Spectrom"},{"issue":"23","key":"6630_CR15","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26237185","volume":"26","author":"O Gould","year":"2021","unstructured":"Gould O, Drabi\u0144ska N, Ratcliffe N, de Lacy Costello B. Hyphenated mass spectrometry versus real-time mass spectrometry techniques for the detection of volatile compounds from the human body. Molecules. 2021;26(23):7185. https:\/\/doi.org\/10.3390\/molecules26237185.","journal-title":"Molecules"},{"key":"6630_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijms.2024.117213","author":"C W\u00fcthrich","year":"2024","unstructured":"W\u00fcthrich C, Giannoukos S. Advances in secondary electrospray ionization for breath analysis and volatilomics. Int J Mass Spectrom. 2024. https:\/\/doi.org\/10.1016\/j.ijms.2024.117213.","journal-title":"Int J Mass Spectrom"},{"issue":"31","key":"6630_CR17","doi-asserted-by":"publisher","first-page":"17004","DOI":"10.1021\/acs.analchem.5c02650","volume":"97","author":"SM Ashbacher","year":"2025","unstructured":"Ashbacher SM, Muddiman DC. Temperature programming secondary electrospray ionization (TP-SESI): a novel approach for mass spectrometry analysis of plant volatile organic compounds. Anal Chem. 2025;97(31):17004\u201311. https:\/\/doi.org\/10.1021\/acs.analchem.5c02650.","journal-title":"Anal Chem"},{"issue":"9","key":"6630_CR18","doi-asserted-by":"publisher","DOI":"10.3390\/metabo10090351","volume":"10","author":"JHJ Lee","year":"2020","unstructured":"Lee JHJ, Zhu J. Optimizing secondary electrospray ionization high-resolution mass spectrometry (SESI-HRMS) for the analysis of volatile fatty acids from gut microbiome. Metabolites. 2020;10(9):351. https:\/\/doi.org\/10.3390\/metabo10090351.","journal-title":"Metabolites"},{"issue":"9","key":"6630_CR19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0108849","volume":"9","author":"T Mitsunami","year":"2014","unstructured":"Mitsunami T, Nishihara M, Galis I, Alamgir KM, Hojo Y, Fujita K, et al. Overexpression of the PAP1 transcription factor reveals a complex regulation of flavonoid and phenylpropanoid metabolism in Nicotiana tabacum plants attacked by Spodoptera litura. PLoS One. 2014;9(9):e108849. https:\/\/doi.org\/10.1371\/journal.pone.0108849.","journal-title":"PLoS One"},{"issue":"1","key":"6630_CR20","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1111\/ppl.12475","volume":"159","author":"X He","year":"2017","unstructured":"He X, Li Y, Lawson D, Xie D. Metabolic engineering of anthocyanins in dark tobacco varieties. Physiol Plant. 2017;159(1):2\u201312. https:\/\/doi.org\/10.1111\/ppl.12475.","journal-title":"Physiol Plant"},{"issue":"6","key":"6630_CR21","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1111\/j.1365-313X.2006.02655.x","volume":"45","author":"D Xie","year":"2006","unstructured":"Xie D, Sharma SB, Wright E, Wang Z, Dixon RA. Metabolic engineering of proanthocyanidins through co\u2010expression of anthocyanidin reductase and the PAP1 MYB transcription factor. Plant J. 2006;45(6):895\u2013907. https:\/\/doi.org\/10.1111\/j.1365-313X.2006.02655.x.","journal-title":"Plant J"},{"issue":"6","key":"6630_CR22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0156673","volume":"11","author":"BE Broeckling","year":"2016","unstructured":"Broeckling BE, Watson RA, Steinwand B, Bush DR. Intronic sequence regulates sugar-dependent expression of Arabidopsis thaliana production of anthocyanin pigment-1\/MYB75. PLoS One. 2016;11(6):e0156673. https:\/\/doi.org\/10.1371\/journal.pone.0156673.","journal-title":"PLoS One"},{"issue":"17","key":"6630_CR23","doi-asserted-by":"publisher","first-page":"5056","DOI":"10.1093\/jxb\/eraf098","volume":"76","author":"J Dieckmann","year":"2025","unstructured":"Dieckmann J, Stracke R, Richter AS. SnRK1 acts upstream of PRODUCTION OF ANTHOCYANIN PIGMENT1 during high light acclimation. J Exp Bot. 2025;76(17):5056\u201370. https:\/\/doi.org\/10.1093\/jxb\/eraf098.","journal-title":"J Exp Bot"},{"issue":"11","key":"6630_CR24","doi-asserted-by":"publisher","first-page":"2070","DOI":"10.1021\/jasms.2c00178","volume":"33","author":"KT Knizner","year":"2022","unstructured":"Knizner KT, Guymon JP, Garrard KP, Bouvr\u00e9e G, Manni J, Hauschild J-P, et al. Next-generation infrared matrix-assisted laser desorption electrospray ionization source for mass spectrometry imaging and high-throughput screening. J Am Soc Mass Spectrom. 2022;33(11):2070\u20137. https:\/\/doi.org\/10.1021\/jasms.2c00178.","journal-title":"J Am Soc Mass Spectrom"},{"issue":"2","key":"6630_CR25","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1021\/jasms.1c00319","volume":"33","author":"KT Knizner","year":"2022","unstructured":"Knizner KT, Bagley MC, Garrard KP, Hauschild JP, Pu F, Elsen NL, et al. Optimized C-trap timing of an Orbitrap 240 mass spectrometer for high-throughput screening and native MS by IR-MALDESI. J Am Soc Mass Spectrom. 2022;33(2):328\u201334. https:\/\/doi.org\/10.1021\/jasms.1c00319.","journal-title":"J Am Soc Mass Spectrom"},{"issue":"1","key":"6630_CR26","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1007\/s13361-017-1809-6","volume":"29","author":"MT Bokhart","year":"2018","unstructured":"Bokhart MT, Nazari M, Garrard KP, Muddiman DC. MSiReader v1.0: evolving open-source mass spectrometry imaging software for targeted and untargeted analyses. J Am Soc Mass Spectrom. 2018;29(1):8\u201316. https:\/\/doi.org\/10.1007\/s13361-017-1809-6.","journal-title":"J Am Soc Mass Spectrom"},{"key":"6630_CR27","doi-asserted-by":"publisher","unstructured":"Alexandrov T, Ovchinnikova K, Palmer A, Kovalev V, Tarasov A, Stuart L, Nigmetzianov R, Fay D, Gaudin M, Lopez CG, Vetter M,\u00a0Swales J, Bokhart M, Kompauer M, McKenzie J, Rappez L, Velickovic D, Lavigne R, Zhang G, Thinagaran D, Ruhland E, Sans M, Triana S, Sammour DA, Aboulmagd S, Bagger C, Strittmatter N, Rigopoulos A, Gemperline E, Joensen AM, Geier B, Quiason C, Weaver E, Prasad M, Balluff B, Nagornov K, Li L, Linscheid M, Hopf C, Heintz D, Liebeke M, Spengler B, Boughton B, Janfelt C, Sharma K, Pineau C, Anderton C, Ellis S, Becker M, P\u00e1ncz\u00e9l J, Violante G. Da, Muddiman D, Goodwin R, Eberlin L, Takats Z, Shahidi-Latham S. METASPACE: a community-populated knowledge base of spatial metabolomes in health and disease. February 3, 2019. https:\/\/doi.org\/10.1101\/539478.","DOI":"10.1101\/539478"},{"issue":"1","key":"6630_CR28","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1038\/nmeth.4072","volume":"14","author":"A Palmer","year":"2017","unstructured":"Palmer A, Phapale P, Chernyavsky I, Lavigne R, Fay D, Tarasov A, et al. FDR-controlled metabolite annotation for high-resolution imaging mass spectrometry. Nat Methods. 2017;14(1):57\u201360. https:\/\/doi.org\/10.1038\/nmeth.4072.","journal-title":"Nat Methods"},{"issue":"1","key":"6630_CR29","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-12-321","volume":"12","author":"K Skogerson","year":"2011","unstructured":"Skogerson K, Wohlgemuth G, Barupal DK, Fiehn O. The volatile compound BinBase mass spectral database. BMC Bioinformatics. 2011;12(1):321. https:\/\/doi.org\/10.1186\/1471-2105-12-321.","journal-title":"BMC Bioinformatics"},{"issue":"2","key":"6630_CR30","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1093\/pcp\/pcr165","volume":"53","author":"FM Afendi","year":"2012","unstructured":"Afendi FM, Okada T, Yamazaki M, Hirai-Morita A, Nakamura Y, Nakamura K, et al. KNApSAcK family databases: integrated metabolite\u2013plant species databases for multifaceted plant research. Plant Cell Physiol. 2012;53(2):e1\u2013e1. https:\/\/doi.org\/10.1093\/pcp\/pcr165.","journal-title":"Plant Cell Physiol"},{"issue":"31","key":"6630_CR31","doi-asserted-by":"publisher","first-page":"19363","DOI":"10.1039\/C7RA00766C","volume":"7","author":"X Fu","year":"2017","unstructured":"Fu X, Zhou Y, Zeng L, Dong F, Mei X, Liao Y, et al. Analytical method for metabolites involved in biosynthesis of plant volatile compounds. RSC Adv. 2017;7(31):19363\u201372. https:\/\/doi.org\/10.1039\/C7RA00766C.","journal-title":"RSC Adv"},{"issue":"11","key":"6630_CR32","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1038\/nbt1251","volume":"24","author":"S Wu","year":"2006","unstructured":"Wu S, Schalk M, Clark A, Miles RB, Coates R, Chappell J. Redirection of cytosolic or plastidic isoprenoid precursors elevates terpene production in plants. Nat Biotechnol. 2006;24(11):1441\u20137. https:\/\/doi.org\/10.1038\/nbt1251.","journal-title":"Nat Biotechnol"},{"issue":"1","key":"6630_CR33","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1146\/annurev.arplant.53.100301.135248","volume":"53","author":"I Feussner","year":"2002","unstructured":"Feussner I, Wasternack C. The lipoxygenase pathway. Annu Rev Plant Biol. 2002;53(1):275\u201397. https:\/\/doi.org\/10.1146\/annurev.arplant.53.100301.135248.","journal-title":"Annu Rev Plant Biol"},{"issue":"3","key":"6630_CR34","first-page":"451","volume":"14","author":"C Gigot","year":"2010","unstructured":"Gigot C, Ongena M, Fauconnier M-L, Wathelet J-P, Du Jardin P, Thonart P. The lipoxygenase metabolic pathway in plants: potential for industrial production of natural green leaf volatiles. Biotechnol Agron Soc Environ. 2010;14(3):451\u201360.","journal-title":"Biotechnol Agron Soc Environ"},{"issue":"5","key":"6630_CR35","doi-asserted-by":"publisher","DOI":"10.3390\/toxics13050364","volume":"13","author":"R Luo","year":"2025","unstructured":"Luo R, Lun X, Gao R, Wang L, Yang Y, Su X, et al. A review of biogenic volatile organic compounds from plants: research progress and future prospects. Toxics. 2025;13(5):364. https:\/\/doi.org\/10.3390\/toxics13050364.","journal-title":"Toxics"},{"issue":"3","key":"6630_CR36","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1105\/tpc.106.046052","volume":"19","author":"T Vellosillo","year":"2007","unstructured":"Vellosillo T, Mart\u00ednez M, L\u00f3pez MA, Vicente J, Casc\u00f3n T, Dolan L, et al. Oxylipins produced by the 9-lipoxygenase pathway in Arabidopsis regulate lateral root development and defense responses through a specific signaling cascade. Plant Cell. 2007;19(3):831\u201346. https:\/\/doi.org\/10.1105\/tpc.106.046052.","journal-title":"Plant Cell"},{"issue":"1","key":"6630_CR37","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1146\/annurev-arplant-042811-105439","volume":"63","author":"H Maeda","year":"2012","unstructured":"Maeda H, Dudareva N. The shikimate pathway and aromatic amino acid biosynthesis in plants. Annu Rev Plant Biol. 2012;63(1):73\u2013105. https:\/\/doi.org\/10.1146\/annurev-arplant-042811-105439.","journal-title":"Annu Rev Plant Biol"},{"key":"6630_CR38","doi-asserted-by":"publisher","DOI":"10.1199\/tab.0132","volume":"8","author":"V Tzin","year":"2010","unstructured":"Tzin V, Galili G. The biosynthetic pathways for shikimate and aromatic amino acids in Arabidopsis thaliana. Arabidopsis Book. 2010;8:e0132. https:\/\/doi.org\/10.1199\/tab.0132.","journal-title":"Arabidopsis Book"},{"key":"6630_CR39","doi-asserted-by":"publisher","DOI":"10.1093\/hr\/uhae220","author":"M Lv","year":"2024","unstructured":"Lv M, Zhang L, Wang Y, Ma L, Yang Y, Zhou X, et al. Floral volatile benzenoids\/phenylpropanoids: biosynthetic pathway, regulation and ecological value. Hortic Res. 2024. https:\/\/doi.org\/10.1093\/hr\/uhae220.","journal-title":"Hortic Res"},{"issue":"19","key":"6630_CR40","doi-asserted-by":"publisher","first-page":"12227","DOI":"10.1021\/acs.chemrev.7b00001","volume":"117","author":"AR Jassbi","year":"2017","unstructured":"Jassbi AR, Zare S, Asadollahi M, Schuman MC. Ecological roles and biological activities of specialized metabolites from the genus Nicotiana. Chem Rev. 2017;117(19):12227\u201380. https:\/\/doi.org\/10.1021\/acs.chemrev.7b00001.","journal-title":"Chem Rev"},{"issue":"19","key":"6630_CR41","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241914570","volume":"24","author":"L Sansone","year":"2023","unstructured":"Sansone L, Milani F, Fabrizi R, Belli M, Cristina M, Zag\u00e0 V, et al. Nicotine: from discovery to biological effects. Int J Mol Sci. 2023;24(19):14570. https:\/\/doi.org\/10.3390\/ijms241914570.","journal-title":"Int J Mol Sci"},{"key":"6630_CR42","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.jare.2021.06.017","volume":"37","author":"M Li","year":"2022","unstructured":"Li M, He X, La Hovary C, Zhu Y, Dong Y, Liu S, et al. A de novo regulation design shows an effectiveness in altering plant secondary metabolism. J Adv Res. 2022;37:43\u201360. https:\/\/doi.org\/10.1016\/j.jare.2021.06.017.","journal-title":"J Adv Res"}],"container-title":["Analytical and Bioanalytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-026-06630-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00216-026-06630-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-026-06630-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T07:27:24Z","timestamp":1786606044000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00216-026-06630-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,20]]},"references-count":42,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["6630"],"URL":"https:\/\/doi.org\/10.1007\/s00216-026-06630-y","relation":{},"ISSN":["1618-2642","1618-2650"],"issn-type":[{"value":"1618-2642","type":"print"},{"value":"1618-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,20]]},"assertion":[{"value":"27 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 May 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 June 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"David C. Muddiman is the part-owner of MSI Software Solutions LLC (Raleigh, NC). He is a member of ABC\u2019s International Advisory Board but was not involved in the peer review of this paper. Sarah M. Ashbacher and De-Yu Xie declare that they have no conflicts of interest.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}