{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T10:00:37Z","timestamp":1790935237311,"version":"4.1.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:00:00Z","timestamp":1790899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:00:00Z","timestamp":1790899200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003706","name":"Korea Research Institute of Standards and Science","doi-asserted-by":"publisher","award":["Grant no. 25011051"],"award-info":[{"award-number":["Grant no. 25011051"]}],"id":[{"id":"10.13039\/501100003706","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anal Bioanal Chem"],"DOI":"10.1007\/s00216-026-06829-z","type":"journal-article","created":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:47:46Z","timestamp":1790934466000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Accurate determination of vitamin B12 in infant formula using isotope dilution-ultrahigh-performance liquid chromatography-tandem mass spectrometry"],"prefix":"10.1007","author":[{"given":"Hyeonwoo","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yared Getachew","family":"Lijalem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaehyoung","family":"Koo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangdoo","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byungjoo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kihwan","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,2]]},"reference":[{"key":"6829_CR1","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1016\/S0584-8547(00)00271-8","volume":"55","author":"S Baker","year":"2000","unstructured":"Baker S, Miller-Ihli N. Determination of cobalamins using capillary electrophoresis inductively coupled plasma mass spectrometry. Spectrochim Acta B. 2000;55:1823\u201332. https:\/\/doi.org\/10.1016\/S0584-8547(00)00271-8.","journal-title":"Spectrochim Acta B"},{"key":"6829_CR2","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1111\/j.1532-5415.1998.tb04534.x","volume":"46","author":"MA Bernard","year":"1998","unstructured":"Bernard MA, Nakonezny PA, Kashner TM. The effect of vitamin B12 deficiency on older veterans and its relationship to health. J Am Geriatr Soc. 1998;46:1199\u2013206. https:\/\/doi.org\/10.1111\/j.1532-5415.1998.tb04534.x.","journal-title":"J Am Geriatr Soc"},{"key":"6829_CR3","doi-asserted-by":"publisher","first-page":"295","DOI":"10.20471\/acc.2019.58.02.13","volume":"58","author":"HM Serin","year":"2019","unstructured":"Serin HM, Arslan EA. Neurological symptoms of vitamin B12 deficiency: analysis of pediatric patients. Acta Clin Croat. 2019;58:295\u2013301. https:\/\/doi.org\/10.20471\/acc.2019.58.02.13.","journal-title":"Acta Clin Croat"},{"key":"6829_CR4","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1136\/adc.77.2.137","volume":"77","author":"U von Schenck","year":"1997","unstructured":"von Schenck U, Bender-G\u00f6tze C, Koletzko B. Persistence of neurological damage induced by dietary vitamin B-12 deficiency in infancy. Arch Dis Child. 1997;77:137\u20139. https:\/\/doi.org\/10.1136\/adc.77.2.137.","journal-title":"Arch Dis Child"},{"key":"6829_CR5","unstructured":"European Commission. Commission Delegated Regulation (EU) 2016\/127 of 25 September 2015 supplementing Regulation (EU) No 609\/2013 of the European Parliament and of the Council as regards the specific compositional and information requirements for infant formula and follow-on formula and as regards requirements on information relating to infant and young child feeding. Off J Eur Union. 2016. 1\u201329."},{"key":"6829_CR6","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/j.foodchem.2018.10.033","volume":"276","author":"H Wang","year":"2019","unstructured":"Wang H, Shou Y, Zhu X, Xu Y, Shi L, Xiang S, et al. Stability of vitamin B12 with the protection of whey proteins and their effects on the gut microbiome. Food Chem. 2019;276:298\u2013306. https:\/\/doi.org\/10.1016\/j.foodchem.2018.10.033.","journal-title":"Food Chem"},{"key":"6829_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.idairyj.2019.104543","volume":"99","author":"Y Li","year":"2019","unstructured":"Li Y, Gill BD, Grainger MN, Manley-Harris M. The analysis of vitamin B12 in milk and infant formula: a review. Int Dairy J. 2019;99:104543. https:\/\/doi.org\/10.1016\/j.idairyj.2019.104543.","journal-title":"Int Dairy J"},{"key":"6829_CR8","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.ymgme.2009.04.005","volume":"97","author":"L Hannibal","year":"2009","unstructured":"Hannibal L, Kim J, Brasch NE, Wang S, Rosenblatt DS, Banerjee R, et al. Processing of alkylcobalamins in mammalian cells: a role for the MMACHC (cblC) gene product. Mol Genet Metab. 2009;97:260\u20136. https:\/\/doi.org\/10.1016\/j.ymgme.2009.04.005.","journal-title":"Mol Genet Metab"},{"key":"6829_CR9","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1093\/jaoac\/85.1.72","volume":"85","author":"HE Indyk","year":"2002","unstructured":"Indyk HE, Persson BS, Caselunghe MCB, Moberg A, Filonzi EL, Woollard DC. Determination of vitamin B12 in milk products and selected foods by optical biosensor protein-binding assay: method comparison. J AOAC Int. 2002;85:72\u201381. https:\/\/doi.org\/10.1093\/jaoac\/85.1.72.","journal-title":"J AOAC Int"},{"key":"6829_CR10","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1016\/B978-012384430-9\/50029-9","volume-title":"Handbook of milk composition","author":"RG Jensen","year":"1995","unstructured":"Jensen RG. Water-soluble vitamins in bovine milk. In: Jensen RG, editor. Handbook of milk composition. San Diego: Elsevier; 1995. p. 688\u201392."},{"key":"6829_CR11","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1079\/BJN19760063","volume":"36","author":"J Farquharson","year":"1976","unstructured":"Farquharson J, Adams J. The forms of vitamin B12 in foods. Br J Nutr. 1976;36:127\u201336. https:\/\/doi.org\/10.1079\/BJN19760063.","journal-title":"Br J Nutr"},{"key":"6829_CR12","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1177\/1559827612450688","volume":"7","author":"R Pawlak","year":"2013","unstructured":"Pawlak R, James PS, Raj S, Cullum-Dugan D, Lucus D. Understanding vitamin B12. Am J Lifestyle Med. 2013;7:60\u20135. https:\/\/doi.org\/10.1177\/1559827612450688.","journal-title":"Am J Lifestyle Med"},{"key":"6829_CR13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0165458","volume":"11","author":"E Greibe","year":"2016","unstructured":"Greibe E, Nexo E. Forms and amounts of vitamin B12 in infant formula: a pilot study. PLoS ONE. 2016;11:e0165458. https:\/\/doi.org\/10.1371\/journal.pone.0165458.","journal-title":"PLoS ONE"},{"key":"6829_CR14","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1021\/jf60105a005","volume":"7","author":"H Lichtenstein","year":"1959","unstructured":"Lichtenstein H, Beloian A, Reynolds H. Vitamin B12 in foodstuffs, comparative vitamin B12 assay of foods of animal origin by Lactobacillus leichmannii and Ochromonas malhamensis. J Agric Food Chem. 1959;7:771\u20134. https:\/\/doi.org\/10.1021\/jf60105a005.","journal-title":"J Agric Food Chem"},{"issue":"2","key":"6829_CR15","first-page":"90","volume":"47","author":"B Kelleher","year":"1990","unstructured":"Kelleher B, Scott J, O\u2019Broin S. Cryo-preservation of Lactobacillus leichmannii for vitamin B12 microbiological assay. Med Lab Sci. 1990;47(2):90\u20136.","journal-title":"Med Lab Sci"},{"key":"6829_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2020.127945","volume":"340","author":"S Bodur","year":"2021","unstructured":"Bodur S, Erarpat S, Bal\u00e7\u0131k U, Bak\u0131rdere S. A rapid, sensitive and accurate determination of cobalamin with double monitoring system: HPLC-UV and HPLC-ICP-OES. Food Chem. 2021;340:127945. https:\/\/doi.org\/10.1016\/j.foodchem.2020.127945.","journal-title":"Food Chem"},{"key":"6829_CR17","doi-asserted-by":"publisher","first-page":"2442","DOI":"10.1007\/s12161-025-02882-z","volume":"18","author":"MM Wolle","year":"2025","unstructured":"Wolle MM, Escavage J, Gray PJ. Development and validation of a method for vitamin B12 measurement in nutritional products by HPLC-ICP-MS. Food Anal Methods. 2025;18:2442\u201356. https:\/\/doi.org\/10.1007\/s12161-025-02882-z.","journal-title":"Food Anal Methods"},{"key":"6829_CR18","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.foodcont.2016.07.027","volume":"72","author":"F Al-Taher","year":"2017","unstructured":"Al-Taher F, Cappozzo J, Zweigenbaum J, Lee HJ, Jackson L, Ryu D. Detection and quantitation of mycotoxins in infant cereals in the US market by LC-MS\/MS using a stable isotope dilution assay. Food Control. 2017;72:27\u201335. https:\/\/doi.org\/10.1016\/j.foodcont.2016.07.027.","journal-title":"Food Control"},{"key":"6829_CR19","doi-asserted-by":"publisher","first-page":"39409","DOI":"10.1039\/C6RA03867K","volume":"6","author":"AS Fayed","year":"2016","unstructured":"Fayed AS, Hegazy M-M. Chromatographic analysis of multicomponent mixture of vitamins B1, B6, B12, benfotiamine and diclofenac; Part II: LC-tandem MS\/MS method for simultaneous quantification of five components mixture in pharmaceutical formulations and human plasma. RSC Adv. 2016;6:39409\u201323. https:\/\/doi.org\/10.1039\/C6RA03867K.","journal-title":"RSC Adv"},{"key":"6829_CR20","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.aca.2006.01.073","volume":"562","author":"X Luo","year":"2006","unstructured":"Luo X, Chen B, Ding L, Tang F, Yao S. HPLC-ESI-MS analysis of vitamin B12 in food products and in multivitamins-multimineral tablets. Anal Chim Acta. 2006;562:185\u20139. https:\/\/doi.org\/10.1016\/j.aca.2006.01.073.","journal-title":"Anal Chim Acta"},{"key":"6829_CR21","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.chroma.2015.07.109","volume":"1428","author":"V P\u00e9rez-Fern\u00e1ndez","year":"2016","unstructured":"P\u00e9rez-Fern\u00e1ndez V, Gentili A, Martinelli A, Caretti F, Curini R. Evaluation of oxidized buckypaper as material for the solid phase extraction of cobalamins from milk: its efficacy as individual and support sorbent of a hydrophilic\u2013lipophilic balance copolymer. J Chromatogr A. 2016;1428:255\u201366. https:\/\/doi.org\/10.1016\/j.chroma.2015.07.109.","journal-title":"J Chromatogr A"},{"key":"6829_CR22","doi-asserted-by":"publisher","first-page":"7649228","DOI":"10.1155\/2022\/7649228","volume":"2022","author":"B Huang","year":"2022","unstructured":"Huang B, Zhang J, Wang M, Cai Z. Determination of vitamin B12 in milk and dairy products by isotope-dilution liquid chromatography tandem mass spectrometry. J Food Qual. 2022;2022:7649228. https:\/\/doi.org\/10.1155\/2022\/7649228.","journal-title":"J Food Qual"},{"key":"6829_CR23","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.aca.2013.11.017","volume":"807","author":"XQ Li","year":"2014","unstructured":"Li XQ, Yang Z, Zhang QH, Li HM. Evaluation of matrix effect in isotope dilution mass spectrometry based on quantitative analysis of chloramphenicol residues in milk powder. Anal Chim Acta. 2014;807:75\u201383. https:\/\/doi.org\/10.1016\/j.aca.2013.11.017.","journal-title":"Anal Chim Acta"},{"key":"6829_CR24","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/j.foodchem.2015.05.114","volume":"190","author":"S Ahn","year":"2016","unstructured":"Ahn S, Lee S, Lee J, Kim B. Accurate determination of ochratoxin A in Korean fermented soybean paste by isotope dilution-liquid chromatography tandem mass spectrometry. Food Chem. 2016;190:368\u201373. https:\/\/doi.org\/10.1016\/j.foodchem.2015.05.114.","journal-title":"Food Chem"},{"key":"6829_CR25","doi-asserted-by":"publisher","first-page":"10722","DOI":"10.1021\/acs.jafc.1c03803","volume":"69","author":"M Wang","year":"2021","unstructured":"Wang M, Asam S, Chen J, Rychlik M. Development of stable isotope dilution assays for the analysis of natural forms of vitamin B12 in meat. J Agric Food Chem. 2021;69:10722\u201330. https:\/\/doi.org\/10.1021\/acs.jafc.1c03803.","journal-title":"J Agric Food Chem"},{"key":"6829_CR26","doi-asserted-by":"publisher","first-page":"5797","DOI":"10.1007\/s00216-023-04860-y","volume":"415","author":"M Wang","year":"2023","unstructured":"Wang M, Schuster K, Asam S, Rychlik M. Challenges in the determination of total vitamin B12 by cyanidation conversion: insights from stable isotope dilution assays. Anal Bioanal Chem. 2023;415:5797\u2013807. https:\/\/doi.org\/10.1007\/s00216-023-04860-y.","journal-title":"Anal Bioanal Chem"},{"key":"6829_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2024.126970","volume":"282","author":"Y Li","year":"2025","unstructured":"Li Y, Gill BD, Manley-Harris M, Grainger MN. A cyanide-free sample preparation methodology prior to determination of vitamin B12 in infant milk formula using hydrophilic interaction liquid chromatography with fluorescence detection. Talanta. 2025;282:126970. https:\/\/doi.org\/10.1016\/j.talanta.2024.126970.","journal-title":"Talanta"},{"key":"6829_CR28","doi-asserted-by":"publisher","first-page":"3939","DOI":"10.1002\/pmic.200900043","volume":"9","author":"NK Bordeerat","year":"2009","unstructured":"Bordeerat NK, Georgieva NI, Klapper DG, Collins LB, Cross TJ, Borchers CH, et al. Accurate quantitation of standard peptides used for quantitative proteomics. Proteomics. 2009;9:3939\u201344. https:\/\/doi.org\/10.1002\/pmic.200900043.","journal-title":"Proteomics"},{"key":"6829_CR29","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1248\/cpb.c20-00296","volume":"69","author":"N Uchiyama","year":"2021","unstructured":"Uchiyama N, Hosoe J, Miura T, Sugimoto N, Ishizuki K, Yamada Y, et al. Determination of absolute purities of hygroscopic substances by quantitative NMR analysis for the standardization of quantitative reagents in the Japanese pharmacopoeia (Part 2). Chem Pharm Bull. 2021;69:26\u201331. https:\/\/doi.org\/10.1248\/cpb.c20-00296.","journal-title":"Chem Pharm Bull"},{"key":"6829_CR30","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/0040-6031(82)87129-3","volume":"59","author":"S Goldstein","year":"1982","unstructured":"Goldstein S, Duca A. Contributions to the analytical chemistry of vitamin B12. The thermal stability of cyanocobalamin, hydroxocobalamin and cobinamide in the solid state. Thermochim Acta. 1982;59:211\u201320. https:\/\/doi.org\/10.1016\/0040-6031(82)87129-3.","journal-title":"Thermochim Acta"},{"key":"6829_CR31","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.chroma.2012.12.047","volume":"1277","author":"S Lee","year":"2013","unstructured":"Lee S, Kim B, Kim J. Development of isotope dilution-liquid chromatography tandem mass spectrometry for the accurate determination of fluoroquinolones in animal meat products: optimization of chromatographic separation for eliminating matrix effects on isotope ratio measurements. J Chromatogr A. 2013;1277:35\u201341. https:\/\/doi.org\/10.1016\/j.chroma.2012.12.047.","journal-title":"J Chromatogr A"},{"key":"6829_CR32","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1016\/j.foodchem.2016.11.112","volume":"221","author":"H Lee","year":"2017","unstructured":"Lee H, Lee J, Choi K, Kim B. Development of isotope dilution-liquid chromatography\/tandem mass spectrometry for the accurate determination of trans-and cis-vitamin K1 isomers in infant formula. Food Chem. 2017;221:729\u201336. https:\/\/doi.org\/10.1016\/j.foodchem.2016.11.112.","journal-title":"Food Chem"},{"key":"6829_CR33","doi-asserted-by":"publisher","first-page":"3139","DOI":"10.5012\/bkcs.2010.31.11.3139","volume":"31","author":"B Kim","year":"2010","unstructured":"Kim B, Hwang E, So H, Son E, Kim Y. Development of a model system of uncertainty evaluations for multiple measurements by isotope dilution mass spectrometry: determination of folic acid in infant formula. Bull Korean Chem Soc. 2010;31:3139\u201344. https:\/\/doi.org\/10.5012\/bkcs.2010.31.11.3139.","journal-title":"Bull Korean Chem Soc"},{"key":"6829_CR34","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1016\/j.foodchem.2010.11.118","volume":"126","author":"Y Lim","year":"2011","unstructured":"Lim Y, Kim B, Ahn S, Kim J. Improvement of accuracy for the determination of vitamin A in infant formula by isotope dilution-liquid chromatography\/tandem mass spectrometry. Food Chem. 2011;126:1393\u20138. https:\/\/doi.org\/10.1016\/j.foodchem.2010.11.118.","journal-title":"Food Chem"},{"key":"6829_CR35","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s12647-010-0017-7","volume":"25","author":"J Vogl","year":"2010","unstructured":"Vogl J, Pritzkow W. Isotope dilution mass spectrometry\u2014a primary method of measurement and its role for RM certification. Mapan. 2010;25:135\u201364. https:\/\/doi.org\/10.1007\/s12647-010-0017-7.","journal-title":"Mapan"},{"key":"6829_CR36","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s00769-002-0520-9","volume":"8","author":"J Choi","year":"2003","unstructured":"Choi J, Hwang E, So H, Kim B. An uncertainty evaluation for multiple measurements by GUM. Accredit Qual Assur. 2003;8:13\u20135. https:\/\/doi.org\/10.1007\/s00769-002-0520-9.","journal-title":"Accredit Qual Assur"},{"key":"6829_CR37","unstructured":"Commission Decision 2002\/657\/EC. Implementing Council Directive 96\/23\/EC concerning the performance of analytical methods and the interpretation of results. Off J Eur Commun. 2002;221:8\u201336."},{"key":"6829_CR38","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1007\/s12562-013-0596-7","volume":"79","author":"Y Ishihara","year":"2013","unstructured":"Ishihara Y, Ueta K, Bito T, Takenaka S, Yabuta Y, Watanabe F. Characterization of vitamin B12 compounds from the brackish-water bivalve Corbicula japonica. Fish Sci. 2013;79:321\u20136. https:\/\/doi.org\/10.1007\/s12562-013-0596-7.","journal-title":"Fish Sci"},{"key":"6829_CR39","doi-asserted-by":"publisher","first-page":"3875","DOI":"10.1007\/s00253-019-09704-3","volume":"103","author":"C Bernhardt","year":"2019","unstructured":"Bernhardt C, Zhu X, Sch\u00fctz D, Fischer M, Bisping B. Cobalamin is produced by Acetobacter pasteurianus DSM 3509. Appl Microbiol Biotechnol. 2019;103:3875\u201385. https:\/\/doi.org\/10.1007\/s00253-019-09704-3.","journal-title":"Appl Microbiol Biotechnol"},{"key":"6829_CR40","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.jchromb.2012.07.012","volume":"905","author":"HA Schwertner","year":"2012","unstructured":"Schwertner HA, Valtier S, Bebarta VS. Liquid chromatographic mass spectrometric (LC\/MS\/MS) determination of plasma hydroxocobalamin and cyanocobalamin concentrations after hydroxocobalamin antidote treatment for cyanide poisoning. J Chromatogr B Anal Technol Biomed Life Sci. 2012;905:10\u20136. https:\/\/doi.org\/10.1016\/j.jchromb.2012.07.012.","journal-title":"J Chromatogr B Anal Technol Biomed Life Sci"},{"key":"6829_CR41","doi-asserted-by":"publisher","first-page":"765","DOI":"10.5851\/kosfa.2015.35.6.765","volume":"35","author":"J Lee","year":"2015","unstructured":"Lee J, Shin J, Park J, Kim H, Ahn J, Kwak B, et al. Analytical determination of vitamin B12 content in infant and toddler milk formulas by liquid chromatography tandem mass spectrometry (LC-MS\/MS). Food Sci Anim Resour. 2015;35:765. https:\/\/doi.org\/10.5851\/kosfa.2015.35.6.765.","journal-title":"Food Sci Anim Resour"},{"key":"6829_CR42","doi-asserted-by":"publisher","first-page":"1266","DOI":"10.3181\/0703-MR-67","volume":"232","author":"F Watanabe","year":"2007","unstructured":"Watanabe F. Vitamin B12 sources and bioavailability. Exp Biol Med (Maywood). 2007;232:1266\u201374. https:\/\/doi.org\/10.3181\/0703-MR-67.","journal-title":"Exp Biol Med (Maywood)"},{"key":"6829_CR43","doi-asserted-by":"publisher","first-page":"2701","DOI":"10.3168\/jds.S0022-0302(97)76230-1","volume":"80","author":"K Sato","year":"1997","unstructured":"Sato K, Wang X, Mizoguchi K. A modified form of a vitamin B12 compound extracted from whey fermented by Lactobacillus helveticus. J Dairy Sci. 1997;80:2701\u20135. https:\/\/doi.org\/10.3168\/jds.S0022-0302(97)76230-1.","journal-title":"J Dairy Sci"},{"key":"6829_CR44","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.5740\/jaoacint.14-119","volume":"97","author":"EC Gim\u00e9nez","year":"2011","unstructured":"Gim\u00e9nez EC. Improved AOAC first action 2011.08 for the analysis of vitamin B12 in infant formula and adult\/pediatric formulas: first action 2014.02. J AOAC Int. 2011;97:1397\u2013402. https:\/\/doi.org\/10.5740\/jaoacint.14-119.","journal-title":"J AOAC Int"},{"key":"6829_CR45","doi-asserted-by":"publisher","DOI":"10.1002\/appl.202200112","volume":"2","author":"T Lenz","year":"2023","unstructured":"Lenz T, Maxones A, Pichner R, Birringer M. Determination of vitamin B12 in commercial pepsin preparations using immunoaffinity chromatography and LC-MS\/MS. Appl Res. 2023;2:e202200112. https:\/\/doi.org\/10.1002\/appl.202200112.","journal-title":"Appl Res"},{"key":"6829_CR46","doi-asserted-by":"publisher","unstructured":"Gim\u00e9nez EC, Martin F. Vitamin B12 (cyanocobalamin) in infant formula adult\/pediatric nutritional formula by liquid chromatography with ultraviolet detection: collaborative study, final action 2014.02. J AOAC Int. 2018;101:1112\u20138.\u00a0https:\/\/doi.org\/10.5740\/jaoacint.17-0452.","DOI":"10.5740\/jaoacint.17-0452"},{"key":"6829_CR47","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.5012\/bkcs.2014.35.4.1057","volume":"35","author":"I Kim","year":"2014","unstructured":"Kim I, Kim B, Hwang E. An approach for the uncertainty evaluation of the overall result from replications of measurement: separately combining individual uncertainty components according to their \u2018systematic\u2019 and \u2018random\u2019 effects. Bull Korean Chem Soc. 2014;35:1057\u201360. https:\/\/doi.org\/10.5012\/bkcs.2014.35.4.1057.","journal-title":"Bull Korean Chem Soc"},{"key":"6829_CR48","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2022.114170","volume":"171","author":"X Wang","year":"2022","unstructured":"Wang X, Li X, Liu X, Zhao X, Li X, Zhang Q, et al. Accurate determination of vitamin B12 in infant formula by liquid chromatography\/isotope dilution high-resolution mass spectrometry. Lwt. 2022;171:114170. https:\/\/doi.org\/10.1016\/j.lwt.2022.114170.","journal-title":"Lwt"},{"key":"6829_CR49","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28010240","volume":"28","author":"\u017d Temova Raku\u0161a","year":"2023","unstructured":"Temova Raku\u0161a \u017d, Ro\u0161kar R, Hickey N, Geremia S. Vitamin B12 in foods, food supplements, and medicines\u2014a review of its role and properties with a focus on its stability. Molecules. 2023;28:240. https:\/\/doi.org\/10.3390\/molecules28010240.","journal-title":"Molecules"}],"container-title":["Analytical and Bioanalytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-026-06829-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00216-026-06829-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00216-026-06829-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:47:48Z","timestamp":1790934468000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00216-026-06829-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,2]]},"references-count":49,"alternative-id":["6829"],"URL":"https:\/\/doi.org\/10.1007\/s00216-026-06829-z","relation":{},"ISSN":["1618-2642","1618-2650"],"issn-type":[{"value":"1618-2642","type":"print"},{"value":"1618-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,2]]},"assertion":[{"value":"1 July 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 September 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 September 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 October 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}