{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T05:49:04Z","timestamp":1790920144190,"version":"4.1.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,3,11]],"date-time":"2008-03-11T00:00:00Z","timestamp":1205193600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Brain Res"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1007\/s00221-008-1336-6","type":"journal-article","created":{"date-parts":[[2008,3,10]],"date-time":"2008-03-10T13:33:23Z","timestamp":1205156003000},"page":"33-43","source":"Crossref","is-referenced-by-count":38,"title":["Acute anoxia stimulates proliferation in adult neural stem cells from the rat brain"],"prefix":"10.1007","volume":"188","author":[{"given":"Heinrich F.","family":"B\u00fcrgers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik W.","family":"Schelshorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Kuschinsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin H.","family":"Maurer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,3,11]]},"reference":[{"key":"1336_CR1","first-page":"255","volume":"7","author":"GE Abdelkarim","year":"2001","unstructured":"Abdelkarim GE, Gertz K, Harms C, Katchanov J, Dirnagl U, Szabo C, Endres M (2001) Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke. Int J Mol Med 7:255\u2013260","journal-title":"Int J Mol Med"},{"key":"1336_CR2","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0022-1759(93)90092-L","volume":"157","author":"TM Buttke","year":"1993","unstructured":"Buttke TM, McCubrey JA, Owen TC (1993) Use of an aqueous soluble tetrazolium\/formazan assay to measure viability and proliferation of lymphokine-dependent cell lines. J Immunol Methods 157:233\u2013240","journal-title":"J Immunol Methods"},{"key":"1336_CR3","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1152\/jappl.1953.6.3.189","volume":"6","author":"LC Clark Jr","year":"1953","unstructured":"Clark LC Jr, Wolf R, Granger D, Taylor Z (1953) Continuous recording of blood oxygen tensions by polarography. J Appl Physiol 6:189\u2013193","journal-title":"J Appl Physiol"},{"key":"1336_CR4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1334.001","volume":"1049","author":"M Csete","year":"2005","unstructured":"Csete M (2005) Oxygen in the cultivation of stem cells. Ann N Y Acad Sci 1049:1\u20138","journal-title":"Ann N Y Acad Sci"},{"key":"1336_CR5","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0166-2236(99)01401-0","volume":"22","author":"U Dirnagl","year":"1999","unstructured":"Dirnagl U, Iadecola C, Moskowitz MA (1999) Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 22:391\u2013397","journal-title":"Trends Neurosci"},{"key":"1336_CR6","doi-asserted-by":"crossref","first-page":"11619","DOI":"10.1073\/pnas.96.20.11619","volume":"96","author":"F Doetsch","year":"1999","unstructured":"Doetsch F, Garcia-Verdugo JM, Alvarez-Buylla A (1999) Regeneration of a germinal layer in the adult mammalian brain. Proc Natl Acad Sci USA 96:11619\u201311624","journal-title":"Proc Natl Acad Sci USA"},{"key":"1336_CR7","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/0003-2697(83)90151-3","volume":"131","author":"J Hofmann","year":"1983","unstructured":"Hofmann J, Sernetz M (1983) A kinetic study on the enzymatic hydrolysis of fluorescein diacetate and fluorescein-di-beta-D-galactopyranoside. Anal Biochem 131:180\u2013186","journal-title":"Anal Biochem"},{"key":"1336_CR8","doi-asserted-by":"crossref","unstructured":"Holst G, Glud RN, Kuhl M, Klimant I (1997) A microoptode array for fine-scale measurement of oxygen distribution. Sensors and actuators B: chemical, 3rd European conference on optical chemical sensors and biosensors 38:122\u2013129","DOI":"10.1016\/S0925-4005(97)80181-5"},{"key":"1336_CR9","doi-asserted-by":"crossref","unstructured":"Klimant I, Kuhl M, Glud RN, Holst G (1997) Optical measurement of oxygen and temperature in microscale: strategies and biological applications. Sensors and actuators B: chemical, 3rd European conference on optical chemical sensors and biosensors 38:29\u201337","DOI":"10.1016\/S0925-4005(97)80168-2"},{"key":"1336_CR10","doi-asserted-by":"crossref","first-page":"3485","DOI":"10.1097\/00001756-200011090-00017","volume":"11","author":"P Lewczuk","year":"2000","unstructured":"Lewczuk P, Hasselblatt M, Kamrowski-Kruck H, Heyer A, Unzicker C, Siren AL, Ehrenreich H (2000) Survival of hippocampal neurons in culture upon hypoxia: effect of erythropoietin. Neuroreport 11:3485\u20133488","journal-title":"Neuroreport"},{"key":"1336_CR11","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.mehy.2006.12.050","volume":"69","author":"X Li","year":"2007","unstructured":"Li X, Zhu L, Chen X, Fan M (2007) Effects of hypoxia on proliferation and differentiation of myoblasts. Med Hypotheses 69:629\u2013636","journal-title":"Med Hypotheses"},{"key":"1336_CR12","doi-asserted-by":"crossref","first-page":"13114","DOI":"10.1523\/JNEUROSCI.4667-06.2006","volume":"26","author":"J Macas","year":"2006","unstructured":"Macas J, Nern C, Plate KH, Momma S (2006) Increased generation of neuronal progenitors after ischemic injury in the aged adult human forebrain. J Neurosci 26:13114\u201313119","journal-title":"J Neurosci"},{"key":"1336_CR13","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1023\/B:NERE.0000023600.25994.11","volume":"29","author":"MH Maurer","year":"2004","unstructured":"Maurer MH, Feldmann RE Jr, F\u00fctterer CD, Butlin J, Kuschinsky W (2004) Comprehensive proteome expression profiling of undifferentiated versus differentiated neural stem cells from adult rat hippocampus. Neurochem Res 29:1129\u20131144","journal-title":"Neurochem Res"},{"key":"1336_CR14","doi-asserted-by":"crossref","first-page":"4430","DOI":"10.1016\/j.febslet.2006.07.012","volume":"580","author":"MH Maurer","year":"2006","unstructured":"Maurer MH, Geomor HK, B\u00fcrgers HF, Schelshorn DW, Kuschinsky W (2006) Adult neural stem cells express glucose transporters GLUT1 and GLUT3 and regulate GLUT3 expression. FEBS Lett 580:4430\u20134434","journal-title":"FEBS Lett"},{"key":"1336_CR15","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.nbd.2004.04.003","volume":"16","author":"JM Plane","year":"2004","unstructured":"Plane JM, Liu R, Wang TW, Silverstein FS, Parent JM (2004) Neonatal hypoxic-ischemic injury increases forebrain subventricular zone neurogenesis in the mouse. Neurobiol Dis 16:585\u2013595","journal-title":"Neurobiol Dis"},{"key":"1336_CR16","doi-asserted-by":"crossref","first-page":"8237","DOI":"10.1523\/JNEUROSCI.1089-04.2004","volume":"24","author":"I Potrovita","year":"2004","unstructured":"Potrovita I, Zhang W, Burkly L, Hahm K, Lincecum J, Wang MZ, Maurer MH, Rossner M, Schneider A, Schwaninger M (2004) Tumor Necrosis Factor-Like Weak inducer of apoptosis-induced neurodegeneration. J Neurosci 24:8237\u20138244","journal-title":"J Neurosci"},{"key":"1336_CR17","doi-asserted-by":"crossref","first-page":"10291","DOI":"10.1523\/JNEUROSCI.22-23-10291.2002","volume":"22","author":"K Ruscher","year":"2002","unstructured":"Ruscher K, Freyer D, Karsch M, Isaev N, Megow D, Sawitzki B, Priller J, Dirnagl U, Meisel A (2002) Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model. J Neurosci 22:10291\u201310301","journal-title":"J Neurosci"},{"key":"1336_CR18","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1038\/sj.jcbfm.9600285","volume":"26","author":"M Santra","year":"2006","unstructured":"Santra M, Katakowski M, Zhang RL, Zhang ZG, Meng H, Jiang F, Chopp M (2006) Protection of adult mouse progenitor cells and human glioma cells by de novo decorin expression in an oxygen- and glucose-deprived cell culture model system. J Cereb Blood Flow Metab 26:1311\u20131322","journal-title":"J Cereb Blood Flow Metab"},{"key":"1336_CR19","doi-asserted-by":"crossref","first-page":"9733","DOI":"10.1523\/JNEUROSCI.21-24-09733.2001","volume":"21","author":"T Shingo","year":"2001","unstructured":"Shingo T, Sorokan ST, Shimazaki T, Weiss S (2001) Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells. J Neurosci 21:9733\u20139743","journal-title":"J Neurosci"},{"key":"1336_CR20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01331024","volume":"14","author":"W Sontag","year":"1977","unstructured":"Sontag W (1977) A comparative kinetic study on the conversion of fluoresceindiacetate to fluorescein in living cells and in vitro. Radiat Environ Biophys 14:1\u201312","journal-title":"Radiat Environ Biophys"},{"key":"1336_CR21","doi-asserted-by":"crossref","first-page":"7377","DOI":"10.1523\/JNEUROSCI.20-19-07377.2000","volume":"20","author":"L Studer","year":"2000","unstructured":"Studer L, Csete M, Lee SH, Kabbani N, Walikonis J, Wold B, McKay R (2000) Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen. J Neurosci 20:7377\u20137383","journal-title":"J Neurosci"},{"key":"1336_CR22","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1602\/neurorx.1.1.17","volume":"1","author":"T Sugawara","year":"2004","unstructured":"Sugawara T, Fujimura M, Noshita N, Kim GW, Saito A, Hayashi T, Narasimhan P, Maier CM, Chan PH (2004) Neuronal death\/survival signaling pathways in cerebral ischemia. NeuroRx 1:17\u201325","journal-title":"NeuroRx"},{"key":"1336_CR23","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1046\/j.1471-4159.1994.62010240.x","volume":"62","author":"SJ Vannucci","year":"1994","unstructured":"Vannucci SJ (1994) Developmental expression of GLUT1 and GLUT3 glucose transporters in rat brain. J Neurochem 62:240\u2013246","journal-title":"J Neurochem"},{"key":"1336_CR24","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1182\/blood-2003-10-3423","volume":"104","author":"W Wagner","year":"2004","unstructured":"Wagner W, Ansorge A, Wirkner U, Eckstein V, Schwager C, Blake J, Miesala K, Selig J, Saffrich R, Ansorge W, Ho AD (2004) Molecular evidence for stem cell function of the slow-dividing fraction among human hematopoietic progenitor cells by genome-wide analysis. Blood 104:675\u2013686","journal-title":"Blood"},{"key":"1336_CR25","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1007\/s00018-004-4144-6","volume":"61","author":"C Wiese","year":"2004","unstructured":"Wiese C, Rolletschek A, Kania G, Blyszczuk P, Tarasov KV, Tarasova Y, Wersto RP, Boheler KR, Wobus AM (2004) Nestin expression\u2014a property of multi-lineage progenitor cells? Cell Mol Life Sci 61:2510\u20132522","journal-title":"Cell Mol Life Sci"},{"key":"1336_CR26","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1182\/blood.V81.9.2223.2223","volume":"81","author":"H Youssoufian","year":"1993","unstructured":"Youssoufian H, Longmore G, Neumann D, Yoshimura A, Lodish HF (1993) Structure, function, and activation of the erythropoietin receptor. Blood 81:2223\u20132236","journal-title":"Blood"},{"key":"1336_CR27","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/jcbfm.1989.3","volume":"9","author":"AC Yu","year":"1989","unstructured":"Yu AC, Gregory GA, Chan PH (1989) Hypoxia-induced dysfunctions and injury of astrocytes in primary cell cultures. J Cereb Blood Flow Metab 9:20\u201328","journal-title":"J Cereb Blood Flow Metab"},{"key":"1336_CR28","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1038\/sj.jcbfm.9600237","volume":"26","author":"RL Zhang","year":"2006","unstructured":"Zhang RL, Zhang ZG, Lu M, Wang Y, Yang JJ, Chopp M (2006) Reduction of the cell cycle length by decreasing G1 phase and cell cycle reentry expand neuronal progenitor cells in the subventricular zone of adult rat after stroke. J Cereb Blood Flow Metab 26:857\u2013863","journal-title":"J Cereb Blood Flow Metab"},{"key":"1336_CR29","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1159\/000092093","volume":"3","author":"L Zhou","year":"2006","unstructured":"Zhou L, Miller CA (2006) Mitogen-activated protein kinase signaling, oxygen sensors and hypoxic induction of neurogenesis. Neurodegener Dis 3:50\u201355","journal-title":"Neurodegener Dis"},{"key":"1336_CR30","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1385\/MN:31:1-3:231","volume":"31","author":"LL Zhu","year":"2005","unstructured":"Zhu LL, Wu LY, Yew DT, Fan M (2005) Effects of hypoxia on the proliferation and differentiation of NSCs. Mol Neurobiol 31:231\u2013242","journal-title":"Mol Neurobiol"}],"container-title":["Experimental Brain Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00221-008-1336-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00221-008-1336-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00221-008-1336-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,2]],"date-time":"2020-05-02T21:36:34Z","timestamp":1588455394000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00221-008-1336-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,11]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["1336"],"URL":"https:\/\/doi.org\/10.1007\/s00221-008-1336-6","relation":{},"ISSN":["0014-4819","1432-1106"],"issn-type":[{"value":"0014-4819","type":"print"},{"value":"1432-1106","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,11]]}}}