{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:12:44Z","timestamp":1762917164437},"reference-count":71,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,9,20]],"date-time":"2008-09-20T00:00:00Z","timestamp":1221868800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Brain Res"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1007\/s00221-008-1559-6","type":"journal-article","created":{"date-parts":[[2008,9,19]],"date-time":"2008-09-19T11:43:20Z","timestamp":1221824600000},"page":"97-112","source":"Crossref","is-referenced-by-count":10,"title":["Eye\u2013head coordination in moderately affected Huntington\u2019s Disease patients: do head movements facilitate gaze shifts?"],"prefix":"10.1007","volume":"192","author":[{"given":"W.","family":"Becker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"J\u00fcrgens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Kassubek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Ecker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Landwehrmeyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,9,20]]},"reference":[{"key":"1559_CR1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0079-6123(08)62678-3","volume":"85","author":"GE Alexander","year":"1990","unstructured":"Alexander GE, Crutcher MD, DeLong MR (1990) Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, \u201cprefrontal\u201d and \u201climbic\u201d functions. Prog Brain Res 85:119\u2013146","journal-title":"Prog Brain Res"},{"key":"1559_CR2","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s00221-005-0143-6","volume":"169","author":"FR Ali","year":"2006","unstructured":"Ali FR, Michell AW, Barker RA, Carpenter RH (2006) The use of quantitative oculometry in the assessment of Huntington\u2019s disease. Exp Brain Res 169:237\u2013245","journal-title":"Exp Brain Res"},{"key":"1559_CR3","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/BF00247585","volume":"69","author":"C Andr\u00e9-Deshays","year":"1988","unstructured":"Andr\u00e9-Deshays C, Berthoz A, Revel M (1988) Eye\u2013head coupling in humans. I. Simultaneous recording of isolated motor units in dorsal neck muscles and horizontal eye movements. Exp Brain Res 69:399\u2013406","journal-title":"Exp Brain Res"},{"key":"1559_CR4","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/BF00231457","volume":"84","author":"C Andr\u00e9-Deshays","year":"1991","unstructured":"Andr\u00e9-Deshays C, Revel M, Berthoz A (1991) Eye\u2013head coupling in humans. II. Phasic components. Exp Brain Res 84:359\u2013366","journal-title":"Exp Brain Res"},{"key":"1559_CR5","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/ng0893-398","volume":"4","author":"SE Andrew","year":"1993","unstructured":"Andrew SE, Goldberg YP, Kremer B, Telenius H, Theilmann J, Adam S, Starr E, Squitieri F, Lin B, Kalchman MA (1993) The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington\u2019s disease. Nat Genet 4:398\u2013403","journal-title":"Nat Genet"},{"key":"1559_CR6","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1136\/jnnp.42.7.581","volume":"42","author":"G Avanzini","year":"1979","unstructured":"Avanzini G, Girotti F, Caraceni T, Spreafico R (1979) Oculomotor disorders in Huntington\u2019s disease. J Neurol Neurosurg Psychiatr 42:581\u2013589","journal-title":"J Neurol Neurosurg Psychiatr"},{"key":"1559_CR7","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1113\/jphysiol.1979.sp012650","volume":"287","author":"GR Barnes","year":"1979","unstructured":"Barnes GR (1979) Vestibulo-ocular function during co-ordinated head and eye movements to acquire visual targets. J Physiol (Lond) 287:127\u2013147","journal-title":"J Physiol (Lond)"},{"key":"1559_CR8","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1093\/acprof:oso\/9780195068207.003.0066","volume-title":"The Head\u2013neck sensory motor system","author":"W Becker","year":"1992","unstructured":"Becker W, J\u00fcrgens R (1992) Gaze saccades to visual targets: does head movement change the metrics? In: Berthoz A, Vidal PP, Graf W (eds) The Head\u2013neck sensory motor system. Oxford University Press, New York, Oxford, pp 427\u2013433"},{"key":"1559_CR9","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0013-4694(86)90005-2","volume":"63","author":"N Beenen","year":"1986","unstructured":"Beenen N, B\u00fcttner U, Lange HW (1986) The diagnostic value of eye movement recording in patients with Huntington\u2019s disease and their offspring. Electroencephalogr Clin Neurophysiol 63:119\u2013127","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"1559_CR10","doi-asserted-by":"crossref","first-page":"2729","DOI":"10.1016\/j.visres.2004.06.006","volume":"44","author":"TM Blekher","year":"2004","unstructured":"Blekher TM, Yee RD, Kirkwood SC, Hake AM, Stout JC, Weaver MR, Foroud TM (2004) Oculomotor control in asymptomatic and recently diagnosed individuals with the genetic marker for Huntington\u2019s disease. Vision Res 44:2729\u20132736","journal-title":"Vision Res"},{"key":"1559_CR11","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1212\/01.wnl.0000227890.87398.c1","volume":"67","author":"T Blekher","year":"2006","unstructured":"Blekher T, Johnson SA, Marshall J, White K, Hui S, Weaver M, Gray J, Yee R, Stout JC, Beristain X, Wojcieszek J, Foroud T (2006) Saccades in presymptomatic and early stages of Huntington\u2019s disease. Neurology 67:394\u2013399","journal-title":"Neurology"},{"key":"1559_CR12","first-page":"11","volume":"74","author":"E Bollen","year":"1986","unstructured":"Bollen E, Reulen JPH, Den Heyer JPH, Van der Kamp W, Roos RAC, Buruma OJS (1986) Horizontal and vertical saccadic eye movement abnormalities in Huntinton\u2019s Chorea. J Neurosci 74:11\u201322","journal-title":"J Neurosci"},{"key":"1559_CR13","first-page":"1202","volume":"60","author":"RR Brinkman","year":"1997","unstructured":"Brinkman RR, Mezei MM, Theilmann J, Almqvist E, Hayden MR (1997) The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size. Am J Hum Genet 60:1202\u20131210","journal-title":"Am J Hum Genet"},{"key":"1559_CR14","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1093\/brain\/105.1.125","volume":"105","author":"JA B\u00fcttner-Ennever","year":"1982","unstructured":"B\u00fcttner-Ennever JA, B\u00fcttner U, Cohen B, Baumgartner G (1982) Vertical gaze paralysis and the rostral interstitial nucleus of the medial longitudinal fasciculus. Brain 105:125\u2013149","journal-title":"Brain"},{"key":"1559_CR15","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.neuropsychologia.2004.06.026","volume":"43","author":"F Chan","year":"2005","unstructured":"Chan F, Armstrong IT, Pari G, Riopelle RJ, Munoz DP (2005) Deficits in saccadic eye-movement control in Parkinson\u2019s disease. Neuropsychologia 43:784\u2013796","journal-title":"Neuropsychologia"},{"key":"1559_CR16","first-page":"307","volume":"86","author":"H Collewijn","year":"1988","unstructured":"Collewijn H, Went LN, Tamminga EP, Vegter-Van der Vlis M (1988) Oculomotor defects in patients with Huntington\u2019s disease and their offspring. J Neurosci 86:307\u2013320","journal-title":"J Neurosci"},{"key":"1559_CR17","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.1152\/jn.1994.72.6.2648","volume":"72","author":"RJ Cowie","year":"1994","unstructured":"Cowie RJ, Robinson DL (1994) Subcortical contributions to head movements in macaques. I. Contrasting effects of electrical stimulation of a medial pontomedullary region and the superior colliculus. J Neurophysiol 72:2648\u20132664","journal-title":"J Neurophysiol"},{"key":"1559_CR18","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1152\/jn.1994.72.6.2665","volume":"72","author":"RJ Cowie","year":"1994","unstructured":"Cowie RJ, Smith MK, Robinson DL (1994) Subcortical contributions to head movements in macaques. II. Connections of a medial pontomedullary head-movement region. J Neurophysiol 72:2665\u20132682","journal-title":"J Neurophysiol"},{"key":"1559_CR19","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1001\/archneur.1991.00530180102024","volume":"48","author":"J Currie","year":"1991","unstructured":"Currie J, Ramsden B, McArthur C, Maruff P (1991) Validation of a clinical antsaccadic eye movement test in the assessment of dementia. Arch Neurol 48:644\u2013648","journal-title":"Arch Neurol"},{"key":"1559_CR20","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1176\/appi.ajp.158.1.100","volume":"158","author":"CE Curtis","year":"2001","unstructured":"Curtis CE, Calkins ME, Grove WM, Feil KJ, Lacono WG (2001) Saccadic disinhibition in patients with acute and remitted schizophrenia and their first-degree biological relatives. Am J Psychiatr 158:100\u2013106","journal-title":"Am J Psychiatr"},{"key":"1559_CR21","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/ng0893-387","volume":"4","author":"M Duyao","year":"1993","unstructured":"Duyao M, Ambrose C, Myers R, Novelletto A, Persichetti F, Frontali M, Folstein S, Ross C, Franz M, Abbott M (1993) Trinucleotide repeat length instability and age of onset in Huntington\u2019s disease. Nat Genet 4:387\u2013392","journal-title":"Nat Genet"},{"key":"1559_CR22","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s00221-004-1840-2","volume":"156","author":"EG Freedman","year":"2004","unstructured":"Freedman EG, Quessy S (2004) Electrical stimulation of rhesus monkey nucleus reticularis gigantocellularis\u2014II. Effects on metrics and kinematics of ongoing gaze shifts to visual targets. Exp Brain Res 156:357\u2013376","journal-title":"Exp Brain Res"},{"key":"1559_CR23","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1152\/jn.1997.77.5.2328","volume":"772","author":"EG Freedman","year":"1997","unstructured":"Freedman EG, Sparks DL (1997) Eye\u2013head coordination during head-unrestrained gaze shifts in rhesus monkey. J Neurophysiol 772:2328\u20132348","journal-title":"J Neurophysiol"},{"key":"1559_CR24","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0006-3223(94)90058-2","volume":"36","author":"J Fukushima","year":"1994","unstructured":"Fukushima J, Fukushima K, Miyasaka K, Yamashita I (1994) Voluntary control of saccadic eye movement in patients with frontal cortical lesions and Parkinsonian patients in comparison with that in schizophrenics. Biol Psychiatry 36:21\u201330","journal-title":"Biol Psychiatry"},{"key":"1559_CR25","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/BF00229630","volume":"109","author":"JH Fuller","year":"1996","unstructured":"Fuller JH (1996) Eye position and target amplitude effects on human visual saccadic latencies. Exp Brain Res 109:457\u2013466","journal-title":"Exp Brain Res"},{"key":"1559_CR26","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s001150050775","volume":"72","author":"P Garcia-Ruiz","year":"2001","unstructured":"Garcia-Ruiz P, Font\u00e1n A, Cenjor C, Ulmer E, Gomez Tortosa E, Sanchez Pernaute R, Rojo A, Garc\u00eda de Y\u00e9benez J (2001) St\u00f6rung der Blicksakkaden bei der Huntington-Krankheit. Klinische Korrelationen. Nervenarzt 72:437\u2013440","journal-title":"Nervenarzt"},{"key":"1559_CR27","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1212\/01.wnl.0000218215.43328.88","volume":"67","author":"CVP Golding","year":"2006","unstructured":"Golding CVP, Danchaivijtr C, Hodgson TL, Tabrizi SJ, Kennard C (2006) Identification of an oculomotor biomarker of preclinical Huntington disease. Neurology 67:485\u2013487","journal-title":"Neurology"},{"key":"1559_CR28","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/BF00229557","volume":"111","author":"JE Goldring","year":"1996","unstructured":"Goldring JE, Dorris MC, Corneil BD, Ballantyne PA, Munoz DP (1996) Combined eye\u2013head gaze shifts to visual and auditory targets in humans. Exp Brain Res 111:68\u201378","journal-title":"Exp Brain Res"},{"key":"1559_CR29","first-page":"239","volume-title":"Functional basis of ocular motility disorders","author":"V Henn","year":"1982","unstructured":"Henn V, B\u00fcttner U (1982) Disorders of horizontal gaze. In: Lennerstrand G, Zee DS, Keller EL (eds) Functional basis of ocular motility disorders. Pergamon Press, Oxford, pp 239\u2013245"},{"key":"1559_CR30","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1093\/brain\/107.2.619","volume":"107","author":"V Henn","year":"1984","unstructured":"Henn V, Lang W, Hepp K, Reisine H (1984) Experimental gaze palsies in monkeys and their relation to human pathology. Brain 107:619\u2013636","journal-title":"Brain"},{"key":"1559_CR31","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1152\/jn.1985.53.1.266","volume":"53","author":"O Hikosaka","year":"1985","unstructured":"Hikosaka O, Wurtz RH (1985a) Modification of saccadic eye movements by GABA-related substances. I. Effect of muscimol and bicuculline in monkey superior colliculus. J Neurophysiol 53:266\u2013291","journal-title":"J Neurophysiol"},{"key":"1559_CR32","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1152\/jn.1985.53.1.292","volume":"53","author":"O Hikosaka","year":"1985","unstructured":"Hikosaka O, Wurtz RH (1985b) Modification of saccadic eye movements by GABA-related substances. II. Effects of muscimol in monkey substantia nigra pars reticulata. J Neurophysiol 53:292\u2013309","journal-title":"J Neurophysiol"},{"key":"1559_CR33","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1152\/physrev.2000.80.3.953","volume":"80","author":"O Hikosaka","year":"2000","unstructured":"Hikosaka O, Takikawa Y, Kawagoe R (2000) Role of the basal ganglia in the control of purposive saccadic eye movements. Physiol Rev 80:953\u2013978","journal-title":"Physiol Rev"},{"key":"1559_CR34","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/0092-8674(93)90585-E","volume":"72","author":"Huntington\u2019s Disease Collaborative Research group","year":"1993","unstructured":"Huntington\u2019s Disease Collaborative Research group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington\u2019s disease chromosomes. Cell 72:971\u2013983","journal-title":"Cell"},{"key":"1559_CR35","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1152\/jn.1996.75.6.2229","volume":"75","author":"CRS Kaneko","year":"1996","unstructured":"Kaneko CRS (1996) Effect of ibotenic acid lesions of the omnipause neurons on saccadic eye movements in rhesus monkey. J Neurophysiol 75:2229\u20132242","journal-title":"J Neurophysiol"},{"key":"1559_CR36","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1152\/jn.00256.2006","volume":"98","author":"TA Knight","year":"2007","unstructured":"Knight TA, Fuchs AF (2007) Contribution of the frontal eye field to gaze shifts in the head-unrestrained monkey: Effects of microstimulation. J Neurophysiol 98:618\u2013634","journal-title":"J Neurophysiol"},{"key":"1559_CR37","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0022-510X(89)90082-8","volume":"91","author":"AH Koeppen","year":"1989","unstructured":"Koeppen AH (1989) The nucleus pontis centralis caudalis in Huntington\u2019s disease. J Neurol Sci 91:129\u2013141","journal-title":"J Neurol Sci"},{"key":"1559_CR38","doi-asserted-by":"crossref","first-page":"3639","DOI":"10.1016\/S0042-6989(96)00169-1","volume":"37","author":"AG Lasker","year":"1997","unstructured":"Lasker AG, Zee DS (1997) Ocular motor abnormalities in Huntington\u2019s disease. Vision Res 37:3639\u20133645","journal-title":"Vision Res"},{"key":"1559_CR39","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1212\/WNL.37.3.364","volume":"37","author":"AG Lasker","year":"1987","unstructured":"Lasker AG, Zee DS, Hain TC, Folstein SE, Singer HS (1987) Saccades in Huntington\u2019s disease: initiation defects and distractibility. Neurology 37:364\u2013370","journal-title":"Neurology"},{"key":"1559_CR40","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1212\/WNL.38.3.427","volume":"38","author":"AG Lasker","year":"1988","unstructured":"Lasker AG, Zee DS, Hain TC, Folstein SE, Singer HS (1988) Saccades in Huntington\u2019s disease: slowing and dysmetria. Neurology 38:427\u2013431","journal-title":"Neurology"},{"key":"1559_CR41","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1113\/jphysiol.1986.sp016043","volume":"373","author":"VP Laurutis","year":"1986","unstructured":"Laurutis VP, Robinson DA (1986) The vestibulo-ocular reflex during human saccadic eye movements. J Physiol (Lond) 373:209\u2013233","journal-title":"J Physiol (Lond)"},{"key":"1559_CR42","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1212\/WNL.33.10.1268","volume":"33","author":"RJ Leigh","year":"1983","unstructured":"Leigh RJ, Newman SA, Folstein SE, Lasker AG, Jensen BA (1983) Abnormal ocular motor control in Huntington\u2019s disease. Neurology 33:1268\u20131275","journal-title":"Neurology"},{"key":"1559_CR43","first-page":"247","volume":"71","author":"RJ Leigh","year":"1985","unstructured":"Leigh RJ, Parhad IM, Clark AW, Buettner-Ennever JA, Folstein SE (1985) Brainstem findings in Huntington\u2019s disease. Possible mechanisms for slow vertical saccades. J Neurosci 71:247\u2013256","journal-title":"J Neurosci"},{"key":"1559_CR44","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s00702-006-0571-x","volume":"114","author":"M M\u00fchlau","year":"2007","unstructured":"M\u00fchlau M, Weindl A, Wohlschl\u00e4ger AM, Gaser C, St\u00e4dtler M, Valet M, Zimmer C, Kassubek J, Peinemann A (2007) Voxel-based morphometry indicates relative preservation of the limbic prefrontal cortex in early Huntington disease. J Neural Transm 114:367\u2013372","journal-title":"J Neural Transm"},{"key":"1559_CR45","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1152\/jn.1998.79.3.1193","volume":"79","author":"DP Munoz","year":"1998","unstructured":"Munoz DP, Istvan PJ (1998) Lateral inhibitory interactions in the intermediate layers of the monkey superior colliculus. J Neurophysiol 79:1193\u20131209","journal-title":"J Neurophysiol"},{"key":"1559_CR46","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/BF01833159","volume":"229","author":"G Oepen","year":"1981","unstructured":"Oepen G, Clarenbach P, Thoden U (1981) Disturbance of eye movements in Huntington\u2019s chorea. Arch Psychiatr Nervenkr 229:205\u2013213","journal-title":"Arch Psychiatr Nervenkr"},{"key":"1559_CR47","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1152\/jn.1988.59.3.997","volume":"59","author":"D P\u00e9lisson","year":"1988","unstructured":"P\u00e9lisson D, Prablanc C, Urquizar C (1988) Vestibuloocular reflex inhibition and gaze saccade control characteristics during eye\u2013head orientation in humans. J Neurophysiol 59:997\u20131013","journal-title":"J Neurophysiol"},{"key":"1559_CR48","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1006\/nbdi.1994.0019","volume":"1","author":"F Persichetti","year":"1994","unstructured":"Persichetti F, Srinidhi J, Kanaley L, Ge P, Myers RH, D\u2019Arrigo K, Barnes GT, MacDonald ME, Vonsattel JP, Gusella JF, Bird ED (1994) Huntington\u2019s disease CAG trinucleotide repeats in pathologically confirmed post-mortem brains. Neurobiol Dis 1:159\u2013166","journal-title":"Neurobiol Dis"},{"key":"1559_CR49","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1093\/brain\/112.2.471","volume":"112","author":"C Pierrot-Deseilligny","year":"1989","unstructured":"Pierrot-Deseilligny C, Rivaud S, Pillon B, Fournier E, Agid Y (1989) Lateral visually-guided saccades in progressive supranuclear palsy. Brain 112:471\u2013487","journal-title":"Brain"},{"key":"1559_CR50","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1196\/annals.1325.023","volume":"1039","author":"C Pierrot-Deseilligny","year":"2005","unstructured":"Pierrot-Deseilligny C, M\u00fcri RM, Nyffeler T, Milea D (2005) The role of the human dorsolateral prefrontal cortex in ocular motor behavior. Ann NY Acad Sci 1039:239\u2013251","journal-title":"Ann NY Acad Sci"},{"key":"1559_CR51","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/s00221-003-1787-8","volume":"156","author":"S Quessy","year":"2004","unstructured":"Quessy S, Freedman EG (2004) Electrical stimulation of rhesus monkey nucleus reticularis gigantocellularis\u2014I. Characteristics of evoked head movements. Exp Brain Res 156:342\u2013356","journal-title":"Exp Brain Res"},{"key":"1559_CR52","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/cne.903460104","volume":"346","author":"FR Robinson","year":"1994","unstructured":"Robinson FR, Phillips JO, Fuchs AF (1994) Coordination of gaze shifts in primates: brainstem inputs to neck and extraocular motoneuron pools. J Comp Neurol 346:43\u201362","journal-title":"J Comp Neurol"},{"key":"1559_CR53","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/ajmg.1400","volume":"105","author":"A Rosenblatt","year":"2001","unstructured":"Rosenblatt A, Brinkman RR, Liang KY, Almqvist EW, Margolis RL, Huang CY, Sherr M, Franz ML, Abbott MH, Hayden MR, Ross CA (2001) Familial influence on age of onset among siblings with Huntington disease. Am J Med Genet 105:399\u2013403","journal-title":"Am J Med Genet"},{"key":"1559_CR54","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/ana.10691","volume":"54","author":"A Rosenblatt","year":"2003","unstructured":"Rosenblatt A, Abbort MH, Gourley LM, Troncoso JC, Margolis RL, Brandt J, Ross C (2003) Predictors of Neuropathological severity in 100 patients with Huntington\u2019s disease. Annals of Neurology 54:488\u2013493","journal-title":"Annals of Neurology"},{"key":"1559_CR55","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3109\/01658109309037004","volume":"13","author":"AJ Rubin","year":"1993","unstructured":"Rubin AJ, King WM, Reinbold KA, Shoulson I (1993) Quantitative longitudinal assessment of saccades in Huntington\u2019s disease. J Clin Neuroophthalmol 13:59\u201366","journal-title":"J Clin Neuroophthalmol"},{"key":"1559_CR56","doi-asserted-by":"crossref","first-page":"422","DOI":"10.3109\/00016488709128270","volume":"104","author":"JA Sharpe","year":"1987","unstructured":"Sharpe JA, Zackon DH (1987) Senescent saccades. Acta Otolaryngol (Stockh) 104:422\u2013428","journal-title":"Acta Otolaryngol (Stockh)"},{"key":"1559_CR57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1212\/WNL.29.1.1","volume":"29","author":"I Shoulson","year":"1979","unstructured":"Shoulson I, Fahn S (1979) Huntington\u2019s disease: clinical care and evaluation. Neurology 29:1\u20133","journal-title":"Neurology"},{"key":"1559_CR58","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00221-002-1207-5","volume":"147","author":"N Smyrnis","year":"2002","unstructured":"Smyrnis N, Evdokimidis I, Stefanis NC, Constantinidis TS, Avramopoulos D, Theleritis C, Paximadis C, Efstratiadis C, Kastrinakis G, Stefanis CN (2002) The antisaccade task in a sample of 2,006 young males. II. Effects of task parameters. Exp Brain Res 147:53\u201363","journal-title":"Exp Brain Res"},{"key":"1559_CR59","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/ng0893-393","volume":"4","author":"RG Snell","year":"1993","unstructured":"Snell RG, MacMillan JC, Cheadle JP, Fenton I, Lazarou LP, Davies P, MacDonald ME, Gusella JF, Harper PS, Shaw DJ (1993) Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington\u2019s disease. Nat Genet 4:393\u2013397","journal-title":"Nat Genet"},{"key":"1559_CR60","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1001\/archneur.1980.00500580071012","volume":"37","author":"JW Spooner","year":"1980","unstructured":"Spooner JW, Sakala SM, Baloh RW (1980) Effect of aging on eye tracking. Arch Neurol 37:575\u2013576","journal-title":"Arch Neurol"},{"key":"1559_CR61","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s002210050715","volume":"126","author":"JS Stahl","year":"1999","unstructured":"Stahl JS (1999) Amplitude of human head movements associated with horizontal saccades. Exp Brain Res 126:41\u201354","journal-title":"Exp Brain Res"},{"key":"1559_CR62","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1093\/brain\/90.3.545","volume":"90","author":"A Starr","year":"1967","unstructured":"Starr A (1967) A disorder of rapid eye movements in Huntigton\u2019s chorea. Brain 90:545\u2013564","journal-title":"Brain"},{"key":"1559_CR63","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1212\/WNL.41.6.875","volume":"41","author":"JR Tian","year":"1991","unstructured":"Tian JR, Zee DS, Lasker AG, Folstein SE (1991) Saccades in Huntington\u2019s disease: predictive tracking and interaction between release of fixation and initiation of saccades. Neurology 41:875\u2013881","journal-title":"Neurology"},{"key":"1559_CR64","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1016\/0028-3932(95)00094-1","volume":"33","author":"TT Tsai","year":"1995","unstructured":"Tsai TT, Lasker AG, Zee DS (1995) Visual attention in Huntington\u2019s disease: the effect of cueing on saccade latencies and manual reaction times. Neuropsychologia 33:1617\u20131626","journal-title":"Neuropsychologia"},{"key":"1559_CR65","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1097\/00005072-199805000-00001","volume":"57","author":"JP Vonsattel","year":"1998","unstructured":"Vonsattel JP, DiFiglia M (1998) Huntington disease. J Neuropathol Exp Neurol 57:369\u2013384","journal-title":"J Neuropathol Exp Neurol"},{"key":"1559_CR66","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1097\/00005072-198511000-00003","volume":"44","author":"JP Vonsattel","year":"1985","unstructured":"Vonsattel JP, Myers RH, Stevens TJ, Ferrante RJ, Bird ED, Richardson EP Jr (1985) Neuropathological classification of Huntington\u2019s disease. J Neuropathol Exp Neurol 44:559\u2013577","journal-title":"J Neuropathol Exp Neurol"},{"key":"1559_CR67","doi-asserted-by":"crossref","first-page":"3498","DOI":"10.1073\/pnas.0308679101","volume":"101","author":"NS Wexler","year":"2004","unstructured":"Wexler NS, Lorimer J, Porter J, Gomez F, Moskowitz C, Shackell E, Marder K, Penchaszadeh G, Roberts SA, Gayan J, Brocklebank D, Cherny SS, Cardon LR, Gray J, Dlouhy SR, Wiktorski S, Hodes ME, Conneally PM, Penney JB, Gusella J, Cha JH, Irizarry M, Rosas D, Hersch S, Hollingsworth Z, MacDonald M, Young AB, Andresen JM, Housman DE, De Young MM, Bonilla E, Stillings T, Negrette A, Snodgrass SR, Martinez-Jaurrieta MD, Ramos-Arroyo MA, Bickham J, Ramos JS, Marshall F, Shoulson I, Rey GJ, Feigin A, Arnheim N, Cevedo-Cruz A, Acosta L, Alvir J, Fischbeck K, Thompson LM, Young A, Dure L, O\u2019Brien CJ, Paulsen J, Brickman A, Krch D, Peery S, Hogarth P, Higgins DS Jr, Landwehrmeyer B (2004) Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington\u2019s disease age of onset. Proc Natl Acad Sci USA 101:3498\u20133503","journal-title":"Proc Natl Acad Sci USA"},{"key":"1559_CR68","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0013-4694(93)90068-7","volume":"86","author":"SJ Wilson","year":"1993","unstructured":"Wilson SJ, Glue P, Ball D, Nutt DJ (1993) Saccadic eye movement parameters in normal subjects. Electroencephalogr Clin Neurophysiol 86:69\u201374","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"1559_CR69","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1016\/S0028-3932(03)00096-4","volume":"41","author":"CT Winograd-Gurvich","year":"2003","unstructured":"Winograd-Gurvich CT, Georgiou-Karistianis N, Evans A, Millist L, Bradshaw JL, Churchyard A, Chiu E, White OB (2003) Hypometric primary saccades and increased variability in visually-guided saccades in Huntington\u2019s disease. Neuropsychologia 41:1683\u20131692","journal-title":"Neuropsychologia"},{"key":"1559_CR70","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1093\/brain\/awm210","volume":"130","author":"RC Wolf","year":"2007","unstructured":"Wolf RC, Vasic N, Sch\u00f6nfeldt-Lecuona C, Landwehrmeyer GB, Ecker D (2007) Dorsolateral prefrontal cortex dysfunction in presymptomatic Huntington\u2019s disease: evidence from event-related fMRI. Brain 130:2845\u20132857","journal-title":"Brain"},{"key":"1559_CR71","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3109\/01658108509079664","volume":"5","author":"WH Zangemeister","year":"1985","unstructured":"Zangemeister WH, Mueller-Jensen A (1985) The co-ordination of gaze movements in Huntington\u2019s disease. Neuro-ophthalmology 5:193\u2013206","journal-title":"Neuro-ophthalmology"}],"container-title":["Experimental Brain Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00221-008-1559-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00221-008-1559-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00221-008-1559-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T11:13:02Z","timestamp":1558696382000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00221-008-1559-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,20]]},"references-count":71,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["1559"],"URL":"https:\/\/doi.org\/10.1007\/s00221-008-1559-6","relation":{},"ISSN":["0014-4819","1432-1106"],"issn-type":[{"value":"0014-4819","type":"print"},{"value":"1432-1106","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,20]]}}}