{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:08:15Z","timestamp":1791911295204,"version":"4.3.4"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2014,6,5]],"date-time":"2014-06-05T00:00:00Z","timestamp":1401926400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Exp Brain Res"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1007\/s00221-014-3997-7","type":"journal-article","created":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T18:58:53Z","timestamp":1401908333000},"page":"3111-3119","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":65,"title":["Conditioned pain modulation in temporomandibular disorders (TMD) pain patients"],"prefix":"10.1007","volume":"232","author":[{"given":"Yuka","family":"Oono","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lene","family":"Baad-Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simple","family":"Futarmal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hikaru","family":"Kohase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Svensson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Arendt-Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,6,5]]},"reference":[{"key":"3997_CR1","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.pain.2008.09.027","volume":"140","author":"L Arendt-Nielsen","year":"2008","unstructured":"Arendt-Nielsen L, Sluka KA, Nie HL (2008) Experimental muscle pain impairs descending inhibition. Pain 140:465\u2013471","journal-title":"Pain"},{"key":"3997_CR2","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s00221-006-0801-3","volume":"179","author":"EE Ayesh","year":"2007","unstructured":"Ayesh EE, Jensen TS, Svensson P (2007) Somatosensory function following painful repetitive electrical stimulation of the human temporomandibular joint and skin. Exp Brain Res 179:415\u2013425","journal-title":"Exp Brain Res"},{"key":"3997_CR3","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/j.1532-2149.2012.00129.x","volume":"16","author":"Y Baba","year":"2012","unstructured":"Baba Y, Kohase H, Oono Y, Fujii-Abe K, Arendt-Nielsen L (2012) Effects of dexmedetomidine on conditioned pain modulation in humans. Eur J Pain 16:1137\u20131147","journal-title":"Eur J Pain"},{"key":"3997_CR4","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.nurt.2009.07.009","volume":"6","author":"K Bannister","year":"2009","unstructured":"Bannister K, Bee LA, Dickenson AH (2009) Preclinical and early clinical investigations related to monoaminergic pain modulation. Neurotherapeutics 6:703\u2013712","journal-title":"Neurotherapeutics"},{"key":"3997_CR5","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/B978-0-7234-3412-2.10007-0","volume-title":"Orofacial pain and headache","author":"R Benoliel","year":"2008","unstructured":"Benoliel R, Sharav Y (2008) Masticatory myofascial pain, tension-type and chronic daily headache. In: Sharav Y, Benoliel R (eds) Orofacial pain and headache. Elsevier, Amsterdam, pp 109\u2013128"},{"key":"3997_CR6","volume-title":"Orofacial pain: guidelines for assessment, diagnosis and management","author":"R Leeuw De","year":"2008","unstructured":"De Leeuw R (2008) Orofacial pain: guidelines for assessment, diagnosis and management, 4th edn. The American Academy of Orofacial Pain, Quintessence","edition":"4"},{"key":"3997_CR7","first-page":"301","volume":"6","author":"SF Dworkin","year":"1992","unstructured":"Dworkin SF, LeResche L (1992) Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique. J Craniomandib Disord 6:301\u2013355","journal-title":"J Craniomandib Disord"},{"key":"3997_CR8","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0006-8993(97)01480-7","volume":"787","author":"T Graven-Nielsen","year":"1998","unstructured":"Graven-Nielsen T, Babenko V, Svensson P, Arendt-Nielsen L (1998) Experimentally induced muscle pain induces hypoalgesia in heterotopic deep tissues, but not in homotopic deep tissues. Brain Res 787:203\u2013210","journal-title":"Brain Res"},{"key":"3997_CR9","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1124\/jpet.104.070656","volume":"311","author":"S Iyengar","year":"2004","unstructured":"Iyengar S, Webster AA, Hemrick-Luecke SK, Xu JY, Simmons RM (2004) Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats. J Pharmacol Exp Ther 311:576\u2013845","journal-title":"J Pharmacol Exp Ther"},{"key":"3997_CR10","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.pain.2008.12.027","volume":"143","author":"CD King","year":"2009","unstructured":"King CD, Wong F, Currie T, Mauderli AP, Fillingim RB, Riley JL 3rd (2009) Deficiency in endogenous modulation of prolonged heat pain in patients with irritable bowel syndrome and temporomandibular disorder. Pain 143:172\u2013178","journal-title":"Pain"},{"key":"3997_CR11","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0304-3959(96)03295-2","volume":"70","author":"E Kosek","year":"1997","unstructured":"Kosek E, Hansson P (1997) Modulatory influence on somatosensory perception from vibration and heterotopic noxious conditioning stimulation (HNCS) in fibromyalgia patients and healthy subjects. Pain 70:41\u201351","journal-title":"Pain"},{"key":"3997_CR12","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/00002508-199709000-00003","volume":"13","author":"S Lautenbacher","year":"1997","unstructured":"Lautenbacher S, Rollman GB (1997) Possible deficiencies of pain modulation in fibromyalgia. Clin J Pain 13:189\u2013195","journal-title":"Clin J Pain"},{"key":"3997_CR13","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0165-0173(02)00186-8","volume":"40","author":"D Bars Le","year":"2002","unstructured":"Le Bars D (2002) The whole body receptive field of dorsal horn multireceptive neurons. Brain Res Rev 40:29\u201344","journal-title":"Brain Res Rev"},{"key":"3997_CR14","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0304-3959(79)90049-6","volume":"6","author":"D Bars Le","year":"1979","unstructured":"Le Bars D, Dickenson AH, Besson JM (1979a) Diffuse noxious inhibitory controls (DNIC). I. Effects on dorsal horn convergent neurons in the rat. Pain 6:283\u2013304","journal-title":"Pain"},{"key":"3997_CR15","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/0304-3959(79)90050-2","volume":"6","author":"D Bars Le","year":"1979","unstructured":"Le Bars D, Dickenson AH, Besson JM (1979b) Diffuse noxious inhibitory controls (DNIC). II. Lack of effect on non-convergent neurons, supraspinal involvement and theoretical implications. Pain 6:305\u2013327","journal-title":"Pain"},{"key":"3997_CR16","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1053\/eujp.2001.0312","volume":"6","author":"AS Leffler","year":"2002","unstructured":"Leffler AS, Hansson P, Kosek E (2002) Somatosensory perception in a remote pain-free area and function of diffuse noxious inhibitory controls (DNIC) in patients suffering from long-term trapezius myalgia. Eur J Pain 6:149\u2013159","journal-title":"Eur J Pain"},{"key":"3997_CR17","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0304-3959(97)00177-2","volume":"74","author":"W Magerl","year":"1998","unstructured":"Magerl W, Wilk SH, Treede RD (1998) Secondary hyperalgesia and perceptual windup following intradermal injection of capsaicin in humans. Pain 74:257\u2013268","journal-title":"Pain"},{"key":"3997_CR18","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0304-3959(95)00068-2","volume":"63","author":"W Maixner","year":"1995","unstructured":"Maixner W, Fillingim R, Booker D, Sigurdsson A (1995) Sensitivity of patients with painful temporomandibular disorders to experimentally evoked pain. Pain 63:341\u2013351","journal-title":"Pain"},{"key":"3997_CR19","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1213\/ANE.0b013e3181d2a768","volume":"110","author":"K Makino","year":"2010","unstructured":"Makino K, Kohase H, Sanada T, Umino M (2010) Phenylephrine suppresses the pain modulation of diffuse noxious inhibitory control in rats. Anesth Analg 110:1215\u20131221","journal-title":"Anesth Analg"},{"key":"3997_CR20","first-page":"364","volume":"25","author":"Y Oono","year":"2011","unstructured":"Oono Y, Wang K, Svensson P, Arendt-Nielsen L (2011a) Conditioned pain modulation evoked by different intensities of mechanical stimuli applied to the craniofacial region in healthy men and women. J Orofac Pain 25:364\u2013375","journal-title":"J Orofac Pain"},{"key":"3997_CR21","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.sjpain.2011.05.006","volume":"2","author":"Y Oono","year":"2011","unstructured":"Oono Y, Nie H, Matos RL, Wang K, Arendt-Nielsen L (2011b) The inter- and intra-individual variance in descending pain modulation evoked by different conditioning stimuli in healthy men. Scand J Pain 2:162\u2013169","journal-title":"Scand J Pain"},{"key":"3997_CR22","first-page":"105","volume":"26","author":"Y Oono","year":"2012","unstructured":"Oono Y, Wang K, Svensson P, Arendt-Nielsen L (2012) Conditioned pain modulation evoked by a mechanical craniofacial stimulus is not influenced by nociceptive stimulation of the temporomandibular joint. J Orofac Pain 26:105\u2013116","journal-title":"J Orofac Pain"},{"issue":"12","key":"3997_CR23","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1016\/j.pain.2013.07.049","volume":"154","author":"Y Oono","year":"2013","unstructured":"Oono Y, Baad-Hansen L, Wang K, Arendt-Nielsen L, Svensson P (2013) Effect of conditioned pain modulation on trigeminal somatosensory function evaluated by quantitative sensory testing. Pain 154(12):2684\u20132690","journal-title":"Pain"},{"key":"3997_CR24","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.pain.2005.08.019","volume":"118","author":"A Pielsticker","year":"2005","unstructured":"Pielsticker A, Haag G, Zaudig M, Lautenbacher S (2005) Impairment of pain inhibition in chronic tension-type headache. Pain 118:215\u2013223","journal-title":"Pain"},{"key":"3997_CR25","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.pain.2006.01.041","volume":"123","author":"R Rolke","year":"2006","unstructured":"Rolke R, Baron R, Maier C, T\u00f6lle TR, Treede RD, Beyer A, Binder A, Birbaumer N, Birklein F, B\u00f6tef\u00fcr IC, Braune S, Flor H, Huge V, Klug R, Landwehrmeyer GB, Magerl W, Maih\u00f6fner C, Rolko C, Schaub C, Scherens A, Sprenger T, Valet M, Wasserka B (2006) Quantitative sensory testing in the German Research Network on neuropathic pain (DFNS): standardized protocol and reference values. Pain 123:231\u2013243","journal-title":"Pain"},{"key":"3997_CR26","first-page":"17","volume":"56","author":"T Sanada","year":"2009","unstructured":"Sanada T, Kohase H, Makino K, Umino M (2009) Effects of alpha-adrenergic agonists on pain modulation in diffuse noxious inhibitory control. J Med Dent Sci 56:17\u201324","journal-title":"J Med Dent Sci"},{"key":"3997_CR27","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1111\/j.1468-2982.2006.01130.x","volume":"26","author":"G Sandrini","year":"2006","unstructured":"Sandrini G, Rossi P, Milanov I, Serrao M, Cecchini AP, Nappi G (2006) Abnormal modulatory influence of diffuse noxious inhibitory controls in migraine and chronic tension-type headache patients. Cephalalgia 26:782\u2013789","journal-title":"Cephalalgia"},{"key":"3997_CR28","first-page":"833","volume":"3","author":"T Smith","year":"2007","unstructured":"Smith T, Nicholson RA (2007) Review of duloxetine in the management of diabetic peripheral neuropathic pain. Vasc Health Risk Manag 3:833\u2013844","journal-title":"Vasc Health Risk Manag"},{"key":"3997_CR29","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.ejpain.2010.06.009","volume":"15","author":"PF Sowman","year":"2011","unstructured":"Sowman PF, Wang K, Svensson P, Arendt-Nielsen L (2011) Diffuse noxious inhibitory control evoked by tonic craniofacial pain in humans. Eur J Pain 15:139\u2013145","journal-title":"Eur J Pain"},{"key":"3997_CR30","first-page":"347","volume":"9","author":"P Svensson","year":"1995","unstructured":"Svensson P, Arendt-Nielsen L, Nielsen H, Larsen JK (1995) Effect of chronic and experimental jaw muscle pain on pain-pressure thresholds and stimulus-response curves. J Orofac Pain 9:347\u2013356","journal-title":"J Orofac Pain"},{"key":"3997_CR31","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1111\/j.1365-2842.2010.02196.x","volume":"38","author":"P Svensson","year":"2011","unstructured":"Svensson P, Baad-Hansen L, Pigg M, List T, Eliav E, Ettlin D, Michelotti A, Tsukiyama Y, Matsuka Y, J\u00e4\u00e4skel\u00e4inen SK, Essick G, Greenspan JD, Drangsholt M, Special Interest Group of Oro-facial Pain (2011) Guidelines and recommendations for assessment of somatosensory function in oro-facial pain conditions\u2014a taskforce report. J Oral Rehabil 38:366\u2013394","journal-title":"J Oral Rehabil"},{"key":"3997_CR32","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s10194-007-0385-8","volume":"8","author":"MD Tommaso","year":"2007","unstructured":"Tommaso MD, Difruscolo O, Sardaro M, Libro G, Pecoraro C, Serpino C, Lamberti P, Livrea P (2007) Effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients. J Headache Pain 8:167\u2013174","journal-title":"J Headache Pain"},{"key":"3997_CR33","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1136\/gut.2003.028514","volume":"53","author":"CH Wilder-Smith","year":"2004","unstructured":"Wilder-Smith CH, Schindler D, Lovblad K, Redmond SM, Nirkko A (2004) Brain functional magnetic resonance imaging of rectal pain and activation of endogenous inhibitory mechanisms in irritable bowel syndrome patient subgroups and healthy controls. Gut 53:1595\u20131601","journal-title":"Gut"},{"key":"3997_CR34","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.pain.2007.10.033","volume":"138","author":"D Yarnitsky","year":"2008","unstructured":"Yarnitsky D, Crispel Y, Eisenberg E, Granovsky Y, Ben-Nun A, Sprecher E, Best LA, Granot M (2008) Prediction of chronic post-operative pain: pre-operative DNIC testing identifies patients at risk. Pain 138:22\u201328","journal-title":"Pain"},{"key":"3997_CR35","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.ejpain.2010.02.004","volume":"14","author":"D Yarnitsky","year":"2010","unstructured":"Yarnitsky D, Arendt-Nielsen L, Bouhassira D, Edwards RR, Fillingim RB, Granot M, Hansson P, Lautenbacher S, Marchand S, Wilder-Smith O (2010) Recommendations on terminology and practice of psychophysical DNIC testing. Eur J Pain 14:339","journal-title":"Eur J Pain"},{"key":"3997_CR36","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.pain.2012.02.021","volume":"153","author":"D Yarnitsky","year":"2012","unstructured":"Yarnitsky D, Granot M, Nahman-Averbuch H, Khamaisi M, Granovsky Y (2012) Conditioned pain modulation predicts duloxetine efficacy in painful diabetic neuropathy. Pain 153:1193\u20131198","journal-title":"Pain"}],"container-title":["Experimental Brain Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00221-014-3997-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00221-014-3997-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00221-014-3997-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T07:23:12Z","timestamp":1558682592000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00221-014-3997-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,5]]},"references-count":36,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["3997"],"URL":"https:\/\/doi.org\/10.1007\/s00221-014-3997-7","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718436692.793499281","asserted-by":"object"}]},"ISSN":["0014-4819","1432-1106"],"issn-type":[{"value":"0014-4819","type":"print"},{"value":"1432-1106","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,5]]}}}