{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T23:07:38Z","timestamp":1778627258659,"version":"3.51.4"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T00:00:00Z","timestamp":1604966400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T00:00:00Z","timestamp":1604966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Exp Brain Res"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1007\/s00221-020-05969-7","type":"journal-article","created":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T05:15:24Z","timestamp":1604985324000},"page":"315-327","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["ALS-CSF-induced structural changes in spinal motor neurons of rat pups cause deficits in motor behaviour"],"prefix":"10.1007","volume":"239","author":[{"given":"Sanjay","family":"Das","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Nalini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8147-9559","authenticated-orcid":false,"given":"T. R.","family":"Laxmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. R.","family":"Raju","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,11,10]]},"reference":[{"key":"5969_CR1","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1002\/cne.21818","volume":"511","author":"J Amendola","year":"2008","unstructured":"Amendola J, Durand J (2008) Morphological differences between wild-type and transgenic superoxide dismutase 1 lumbar motoneurons in postnatal mice. J Comp Neurol 511:329\u2013341. https:\/\/doi.org\/10.1002\/cne.21818","journal-title":"J Comp Neurol"},{"key":"5969_CR2","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1080\/146608200300079536","volume":"1","author":"BR Brooks","year":"2000","unstructured":"Brooks BR, Miller RG, Swash M, Munsat TL (2000) El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 1:293\u2013299","journal-title":"Amyotroph Lateral Scler Other Motor Neuron Disord"},{"key":"5969_CR3","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1002\/brb3.104","volume":"3","author":"C Casas","year":"2013","unstructured":"Casas C, Herrando-Grabulosa M, Manzano R, Mancuso R, Osta R, Navarro X (2013) Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis. Brain Behav 3:145\u2013158. https:\/\/doi.org\/10.1002\/brb3.104","journal-title":"Brain Behav"},{"key":"5969_CR4","doi-asserted-by":"publisher","first-page":"2122","DOI":"10.3389\/fimmu.2018.02122","volume":"9","author":"X Chen","year":"2018","unstructured":"Chen X, Hu Y, Cao Z, Liu Q, Cheng Y (2018) Cerebrospinal fluid inflammatory cytokine aberrations in Alzheimer\u2019s disease, Parkinson\u2019s disease and amyotrophic lateral sclerosis: a systematic review and meta-analysis. Front Immunol 9:2122. https:\/\/doi.org\/10.3389\/fimmu.2018.02122","journal-title":"Front Immunol"},{"key":"5969_CR5","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1002\/mus.20658","volume":"34","author":"A Czaplinski","year":"2006","unstructured":"Czaplinski A, Yen AA, Simpson EP, Appel SH (2006) Predictability of disease progression in amyotrophic lateral sclerosis. Muscle Nerve 34:702\u2013708. https:\/\/doi.org\/10.1002\/mus.20658","journal-title":"Muscle Nerve"},{"key":"5969_CR6","doi-asserted-by":"publisher","first-page":"e82654","DOI":"10.1371\/journal.pone.0082654","volume":"8","author":"P d'Errico","year":"2013","unstructured":"d\u2019Errico P, Boido M, Piras A et al (2013) Selective vulnerability of spinal and cortical motor neuron subpopulations in delta7 SMA mice. PLoS ONE 8:e82654. https:\/\/doi.org\/10.1371\/journal.pone.0082654","journal-title":"PLoS ONE"},{"key":"5969_CR7","doi-asserted-by":"publisher","DOI":"10.1002\/9781444341256","volume-title":"Neurodegeneration: the molecular pathology of dementia and movement disorders","author":"D Dickson","year":"2011","unstructured":"Dickson D, Weller RO (2011) Neurodegeneration: the molecular pathology of dementia and movement disorders. Wiley, New York"},{"key":"5969_CR8","doi-asserted-by":"publisher","first-page":"1723","DOI":"10.1113\/jp275498","volume":"596","author":"SS Dukkipati","year":"2018","unstructured":"Dukkipati SS, Garrett TL, Elbasiouny SM (2018) The vulnerability of spinal motoneurons and soma size plasticity in a mouse model of amyotrophic lateral sclerosis. J Physiol 596:1723\u20131745. https:\/\/doi.org\/10.1113\/jp275498","journal-title":"J Physiol"},{"key":"5969_CR9","volume-title":"Neuropathology E-book: a reference text of CNS pathology","author":"D Ellison","year":"2012","unstructured":"Ellison D, Love S, Chimelli LMC et al (2012) Neuropathology E-book: a reference text of CNS pathology. Elsevier Health Sciences, Amsterdam"},{"key":"5969_CR10","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/0006-8993(89)91340-1","volume":"479","author":"JM Fitch","year":"1989","unstructured":"Fitch JM, Juraska JM, Washington LW (1989) The dendritic morphology of pyramidal neurons in the rat hippocampal CA3 area. I. Cell types. Brain Res 479:105\u2013114. https:\/\/doi.org\/10.1016\/0006-8993(89)91340-1","journal-title":"Brain Res"},{"key":"5969_CR11","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1172\/jci17610","volume":"111","author":"C Guegan","year":"2003","unstructured":"Guegan C, Przedborski S (2003) Programmed cell death in amyotrophic lateral sclerosis. J Clin Investig 111:153\u2013161. https:\/\/doi.org\/10.1172\/jci17610","journal-title":"J Clin Investig"},{"key":"5969_CR12","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/0014-4886(79)90129-8","volume":"63","author":"RP Hammer Jr","year":"1979","unstructured":"Hammer RP Jr, Tomiyasu U, Scheibel AB (1979) Degeneration of the human Betz cell due to amyotrophic lateral sclerosis. Exp Neurol 63:336\u2013346","journal-title":"Exp Neurol"},{"key":"5969_CR13","doi-asserted-by":"publisher","first-page":"2313","DOI":"10.1093\/brain\/awq167","volume":"133","author":"E Hedlund","year":"2010","unstructured":"Hedlund E, Karlsson M, Osborn T, Ludwig W, Isacson O (2010) Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection. Brain 133:2313\u20132330. https:\/\/doi.org\/10.1093\/brain\/awq167","journal-title":"Brain"},{"key":"5969_CR14","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1097\/00005072-199810000-00002","volume":"57","author":"PG Ince","year":"1998","unstructured":"Ince PG, Tomkins J, Slade JY, Thatcher NM, Shaw PJ (1998) Amyotrophic lateral sclerosis associated with genetic abnormalities in the gene encoding Cu\/Zn superoxide dismutase: molecular pathology of five new cases, and comparison with previous reports and 73 sporadic cases of ALS. J Neuropathol Exp Neurol 57:895\u2013904. https:\/\/doi.org\/10.1097\/00005072-199810000-00002","journal-title":"J Neuropathol Exp Neurol"},{"key":"5969_CR15","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1080\/14660820510038538","volume":"6","author":"J Kassubek","year":"2005","unstructured":"Kassubek J, Unrath A, Huppertz HJ, Lule D, Ethofer T, Sperfeld AD, Ludolph AC (2005) Global brain atrophy and corticospinal tract alterations in ALS, as investigated by voxel-based morphometry of 3-D MRI. Amyotroph Lateral Scler Other Motor Neuron Disord 6:213\u2013220. https:\/\/doi.org\/10.1080\/14660820510038538","journal-title":"Amyotroph Lateral Scler Other Motor Neuron Disord"},{"issue":"Pt 4","key":"5969_CR16","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1093\/brain\/117.4.747","volume":"117","author":"JA Kiernan","year":"1994","unstructured":"Kiernan JA, Hudson AJ (1994) Frontal lobe atrophy in motor neuron diseases. Brain 117(Pt 4):747\u2013757. https:\/\/doi.org\/10.1093\/brain\/117.4.747","journal-title":"Brain"},{"key":"5969_CR17","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1038\/nature08971","volume":"465","author":"H Maruyama","year":"2010","unstructured":"Maruyama H, Morino H, Ito H et al (2010) Mutations of optineurin in amyotrophic lateral sclerosis. Nature 465:223\u2013226. https:\/\/doi.org\/10.1038\/nature08971","journal-title":"Nature"},{"key":"5969_CR18","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.jneumeth.2006.06.001","volume":"158","author":"C Monville","year":"2006","unstructured":"Monville C, Torres EM, Dunnett SB (2006) Comparison of incremental and accelerating protocols of the rotarod test for the assessment of motor deficits in the 6-OHDA model. J Neurosci Methods 158:219\u2013223. https:\/\/doi.org\/10.1016\/j.jneumeth.2006.06.001","journal-title":"J Neurosci Methods"},{"key":"5969_CR19","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.bbadis.2016.11.025","volume":"1863","author":"JR Morrice","year":"2017","unstructured":"Morrice JR, Gregory-Evans CY, Shaw CA (2017) Necroptosis in amyotrophic lateral sclerosis and other neurological disorders. Biochim Biophys Acta Mol Basis Dis 1863:347\u2013353. https:\/\/doi.org\/10.1016\/j.bbadis.2016.11.025","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"5969_CR20","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1097\/00005072-199804000-00004","volume":"57","author":"M Nagao","year":"1998","unstructured":"Nagao M, Misawa H, Kato S, Hirai S (1998) Loss of cholinergic synapses on the spinal motor neurons of amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 57:329\u2013333. https:\/\/doi.org\/10.1097\/00005072-199804000-00004","journal-title":"J Neuropathol Exp Neurol"},{"key":"5969_CR21","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/BF00454899","volume":"86","author":"K Nihei","year":"1993","unstructured":"Nihei K, McKee AC, Kowall NW (1993) Patterns of neuronal degeneration in the motor cortex of amyotrophic lateral sclerosis patients. Acta Neuropathol 86:55\u201364","journal-title":"Acta Neuropathol"},{"key":"5969_CR22","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1111\/j.1440-1827.1995.tb03418.x","volume":"45","author":"Y Oda","year":"1995","unstructured":"Oda Y, Imai S, Nakanishi I, Ichikawa T, Deguchi T (1995) Immunohistochemical study on choline acetyltransferase in the spinal cord of patients with amyotrophic lateral sclerosis. Pathol Int 45:933\u2013939","journal-title":"Pathol Int"},{"key":"5969_CR23","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1111\/j.1750-3639.2003.tb00002.x","volume":"13","author":"YS Piao","year":"2003","unstructured":"Piao YS, Wakabayashi K, Kakita A et al (2003) Neuropathology with clinical correlations of sporadic amyotrophic lateral sclerosis: 102 autopsy cases examined between 1962 and 2000. Brain Pathol 13:10\u201322","journal-title":"Brain Pathol"},{"key":"5969_CR24","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1007\/s10517-017-3609-1","volume":"162","author":"VV Porseva","year":"2017","unstructured":"Porseva VV, Shilkin VV, Strelkov AA, Krasnov IB, Masliukov PM (2017) Changes in the neurochemical composition of motor neurons of the spinal cord in mice under conditions of space flight. Bull Exp Biol Med 162:336\u2013339. https:\/\/doi.org\/10.1007\/s10517-017-3609-1","journal-title":"Bull Exp Biol Med"},{"key":"5969_CR25","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1080\/08037060601145489","volume":"8","author":"PY Ramamohan","year":"2007","unstructured":"Ramamohan PY, Gourie-Devi M, Nalini A, Shobha K, Ramamohan Y, Joshi P, Raju TR (2007) Cerebrospinal fluid from amyotrophic lateral sclerosis patients causes fragmentation of the Golgi apparatus in the neonatal rat spinal cord. Amyotroph Lateral Scler 8:79\u201382. https:\/\/doi.org\/10.1080\/08037060601145489","journal-title":"Amyotroph Lateral Scler"},{"key":"5969_CR26","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1006\/neur.1995.0048","volume":"4","author":"MS Rao","year":"1995","unstructured":"Rao MS, Devi MG, Nalini A, Shahani N, Raju TR (1995) Neurofilament phosphorylation is increased in ventral horn neurons of neonatal rat spinal cord exposed to cerebrospinal fluid from patients with amyotrophic lateral sclerosis. Neurodegeneration 4:397\u2013401","journal-title":"Neurodegeneration"},{"key":"5969_CR27","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1080\/17482960802267530","volume":"10","author":"L Roccatagliata","year":"2009","unstructured":"Roccatagliata L, Bonzano L, Mancardi G, Canepa C, Caponnetto C (2009) Detection of motor cortex thinning and corticospinal tract involvement by quantitative MRI in amyotrophic lateral sclerosis. Amyotroph Lateral Scler 10:47\u201352. https:\/\/doi.org\/10.1080\/17482960802267530","journal-title":"Amyotroph Lateral Scler"},{"key":"5969_CR28","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.bbr.2009.09.009","volume":"206","author":"R Sankaranarayani","year":"2010","unstructured":"Sankaranarayani R, Nalini A, Rao Laxmi T, Raju TR (2010) Altered neuronal activities in the motor cortex with impaired motor performance in adult rats observed after infusion of cerebrospinal fluid from amyotrophic lateral sclerosis patients. Behav Brain Res 206:109\u2013119. https:\/\/doi.org\/10.1016\/j.bbr.2009.09.009","journal-title":"Behav Brain Res"},{"key":"5969_CR29","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s00702-013-1071-4","volume":"121","author":"R Sankaranarayani","year":"2014","unstructured":"Sankaranarayani R, Raghavan M, Nalini A, Laxmi TR, Raju TR (2014) Reach task-associated excitatory overdrive of motor cortical neurons following infusion with ALS-CSF. J Neural Transm (Vienna) 121:49\u201358. https:\/\/doi.org\/10.1007\/s00702-013-1071-4","journal-title":"J Neural Transm (Vienna)"},{"key":"5969_CR30","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/s1474-4422(05)70142-3","volume":"4","author":"S Sathasivam","year":"2005","unstructured":"Sathasivam S, Shaw PJ (2005) Apoptosis in amyotrophic lateral sclerosis\u2014what is the evidence? Lancet Neurol 4:500\u2013509. https:\/\/doi.org\/10.1016\/s1474-4422(05)70142-3","journal-title":"Lancet Neurol"},{"key":"5969_CR31","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1006\/exnr.1997.6651","volume":"149","author":"N Shahani","year":"1998","unstructured":"Shahani N, Nalini A, Gourie-Devi M, Raju TR (1998) Reactive astrogliosis in neonatal rat spinal cord after exposure to cerebrospinal fluid from patients with amyotrophic lateral sclerosis. Exp Neurol 149:295\u2013298. https:\/\/doi.org\/10.1006\/exnr.1997.6651","journal-title":"Exp Neurol"},{"key":"5969_CR32","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/S0306-4522(00)00462-0","volume":"102","author":"BS Shankaranarayana Rao","year":"2001","unstructured":"Shankaranarayana Rao BS, Govindaiah LTR, Meti BL, Raju TR (2001) Subicular lesions cause dendritic atrophy in CA1 and CA3 pyramidal neurons of the rat hippocampus. Neuroscience 102:319\u2013327","journal-title":"Neuroscience"},{"key":"5969_CR33","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.031997","author":"S Shanmukha","year":"2018","unstructured":"Shanmukha S, Narayanappa G, Nalini A, Alladi PA, Raju TR (2018) Sporadic amyotrophic lateral sclerosis (SALS)\u2014skeletal muscle response to cerebrospinal fluid from SALS patients in a rat model. Dis Model Mech. https:\/\/doi.org\/10.1242\/dmm.031997","journal-title":"Dis Model Mech"},{"key":"5969_CR34","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1007\/s11064-015-1779-7","volume":"41","author":"A Sharma","year":"2016","unstructured":"Sharma A, Varghese AM, Vijaylakshmi K et al (2016) Cerebrospinal fluid from sporadic amyotrophic lateral sclerosis patients induces mitochondrial and lysosomal dysfunction. Neurochem Res 41:965\u2013984. https:\/\/doi.org\/10.1007\/s11064-015-1779-7","journal-title":"Neurochem Res"},{"key":"5969_CR35","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.12113","author":"L Shoenfeld","year":"2014","unstructured":"Shoenfeld L, Westenbroek RE, Fisher E et al (2014) Soma size and Cav1.3 channel expression in vulnerable and resistant motoneuron populations of the SOD1G93A mouse model of ALS. Physiol Rep. https:\/\/doi.org\/10.14814\/phy2.12113","journal-title":"Physiol Rep"},{"key":"5969_CR36","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1007\/BF00691322","volume":"55","author":"G Sobue","year":"1981","unstructured":"Sobue G, Matsuoka Y, Mukai E, Takayanagi T, Sobue I, Hashizume Y (1981) Spinal and cranial motor nerve roots in amyotrophic lateral sclerosis and X-linked recessive bulbospinal muscular atrophy: morphometric and teased-fiber study. Acta Neuropathol 55:227\u2013235","journal-title":"Acta Neuropathol"},{"key":"5969_CR37","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.jns.2005.12.003","volume":"244","author":"B Stephens","year":"2006","unstructured":"Stephens B, Guiloff RJ, Navarrete R, Newman P, Nikhar N, Lewis P (2006) Widespread loss of neuronal populations in the spinal ventral horn in sporadic motor neuron disease. A morphometric study. J Neurol Sci 244:41\u201358. https:\/\/doi.org\/10.1016\/j.jns.2005.12.003","journal-title":"J Neurol Sci"},{"key":"5969_CR38","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/0165-0270(95)00017-O","volume":"61","author":"DA Stuart","year":"1995","unstructured":"Stuart DA, Oorschot DE (1995) Embedding, sectioning, immunocytochemical and stereological methods that optimise research on the lesioned adult rat spinal cord. J Neurosci Methods 61:5\u201314","journal-title":"J Neurosci Methods"},{"key":"5969_CR39","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1007\/BF00690971","volume":"42","author":"M Tomonaga","year":"1978","unstructured":"Tomonaga M, Saito M, Yoshimura M, Shimada H, Tohgi H (1978) Ultrastructure of the Bunina bodies in anterior horn cells of amyotrophic lateral sclerosis. Acta Neuropathol 42:81\u201386","journal-title":"Acta Neuropathol"},{"key":"5969_CR40","doi-asserted-by":"publisher","first-page":"369","DOI":"10.3109\/17482960903420140","volume":"11","author":"MR Turner","year":"2010","unstructured":"Turner MR, Brockington A, Scaber J, Hollinger H, Marsden R, Shaw PJ, Talbot K (2010) Pattern of spread and prognosis in lower limb-onset ALS. Amyotroph Lateral Scler 11:369\u2013373. https:\/\/doi.org\/10.3109\/17482960903420140","journal-title":"Amyotroph Lateral Scler"},{"key":"5969_CR41","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.jchemneu.2016.01.001","volume":"76","author":"DJ Vidyadhara","year":"2016","unstructured":"Vidyadhara DJ, Yarreiphang H, Abhilash PL, Raju TR, Alladi PA (2016) Differential expression of calbindin in nigral dopaminergic neurons in two mice strains with differential susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Chem Neuroanat 76:82\u201389. https:\/\/doi.org\/10.1016\/j.jchemneu.2016.01.001","journal-title":"J Chem Neuroanat"},{"key":"5969_CR42","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.brainres.2009.01.041","volume":"1263","author":"K Vijayalakshmi","year":"2009","unstructured":"Vijayalakshmi K, Alladi PA, Sathyaprabha TN, Subramaniam JR, Nalini A, Raju TR (2009) Cerebrospinal fluid from sporadic amyotrophic lateral sclerosis patients induces degeneration of a cultured motor neuron cell line. Brain Res 1263:122\u2013133. https:\/\/doi.org\/10.1016\/j.brainres.2009.01.041","journal-title":"Brain Res"},{"key":"5969_CR43","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1016\/j.nbd.2010.12.005","volume":"41","author":"K Vijayalakshmi","year":"2011","unstructured":"Vijayalakshmi K, Alladi PA, Ghosh S et al (2011) Evidence of endoplasmic reticular stress in the spinal motor neurons exposed to CSF from sporadic amyotrophic lateral sclerosis patients. Neurobiol Dis 41:695\u2013705. https:\/\/doi.org\/10.1016\/j.nbd.2010.12.005","journal-title":"Neurobiol Dis"},{"key":"5969_CR44","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1002\/(SICI)1097-4547(19970115)47:2<134::AID-JNR2>3.0.CO;2-G","volume":"47","author":"W Wang","year":"1997","unstructured":"Wang W, Salvaterra PM, Loera S, Chiu AY (1997) Brain-derived neurotrophic factor spares choline acetyltransferase mRNA following axotomy of motor neurons in vivo. J Neurosci Res 47:134\u2013143","journal-title":"J Neurosci Res"},{"issue":"Pt 3","key":"5969_CR45","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1046\/j.1469-7580.1997.19130347.x","volume":"191","author":"UJ Weber","year":"1997","unstructured":"Weber UJ, Bock T, Buschard K, Pakkenberg B (1997) Total number and size distribution of motor neurons in the spinal cord of normal and EMC-virus infected mice\u2014a stereological study. J Anat 191(Pt 3):347\u2013353. https:\/\/doi.org\/10.1046\/j.1469-7580.1997.19130347.x","journal-title":"J Anat"},{"key":"5969_CR46","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1006\/exnr.1996.0159","volume":"141","author":"R Wetts","year":"1996","unstructured":"Wetts R, Vaughn JE (1996) Differential vulnerability of two subsets of spinal motor neurons in amyotrophic lateral sclerosis. Exp Neurol 141:248\u2013255. https:\/\/doi.org\/10.1006\/exnr.1996.0159","journal-title":"Exp Neurol"},{"key":"5969_CR47","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1007\/s11064-006-9166-z","volume":"31","author":"Z Xu","year":"2006","unstructured":"Xu Z, Chen S, Li X, Luo G, Li L, Le W (2006) Neuroprotective effects of (\u2212)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis. Neurochem Res 31:1263\u20131269. https:\/\/doi.org\/10.1007\/s11064-006-9166-z","journal-title":"Neurochem Res"}],"container-title":["Experimental Brain Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00221-020-05969-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00221-020-05969-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00221-020-05969-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T22:30:55Z","timestamp":1613687455000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00221-020-05969-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,10]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["5969"],"URL":"https:\/\/doi.org\/10.1007\/s00221-020-05969-7","relation":{},"ISSN":["0014-4819","1432-1106"],"issn-type":[{"value":"0014-4819","type":"print"},{"value":"1432-1106","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,10]]},"assertion":[{"value":"24 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 October 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 November 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}