{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:02:30Z","timestamp":1792724550529,"version":"4.5.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2014,7,24]],"date-time":"2014-07-24T00:00:00Z","timestamp":1406160000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Calcif Tissue Int"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1007\/s00223-014-9894-z","type":"journal-article","created":{"date-parts":[[2014,7,23]],"date-time":"2014-07-23T02:33:12Z","timestamp":1406082792000},"page":"308-316","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Lean Mass, Muscle Strength and Gene Expression in Community Dwelling Older Men: Findings from the Hertfordshire Sarcopenia Study (HSS)"],"prefix":"10.1007","volume":"95","author":[{"given":"Harnish P.","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasser","family":"Al-Shanti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy C.","family":"Davies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila J.","family":"Barton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miranda D.","family":"Grounds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross L.","family":"Tellam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire E.","family":"Stewart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyrus","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avan Aihie","family":"Sayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,7,24]]},"reference":[{"key":"9894_CR1","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1093\/ageing\/afs197","volume":"42","author":"HP Patel","year":"2013","unstructured":"Patel HP, Syddall HE, Jameson K, Robinson S, Denison H, Roberts HC, Edwards M, Dennison E, Cooper C, Aihie Sayer A (2013) Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS). Age Ageing 42:378\u2013384","journal-title":"Age Ageing"},{"key":"9894_CR2","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ageing\/afq034","volume":"39","author":"AJ Cruz-Jentoft","year":"2010","unstructured":"Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinkova E, Vandewoude M, Zamboni M (2010) Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing 39:412\u2013423","journal-title":"Age Ageing"},{"key":"9894_CR3","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1046\/j.1532-5415.2003.51105.x","volume":"51","author":"AB Newman","year":"2003","unstructured":"Newman AB, Haggerty CL, Goodpaster B, Harris T, Kritchevsky S, Nevitt M, Miles TP, Visser M (2003) Strength and muscle quality in a well-functioning cohort of older adults: The Health, Aging and Body Composition Study. J Am Geriatr Soc 51:323\u2013330","journal-title":"J Am Geriatr Soc"},{"key":"9894_CR4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1023\/A:1015234709314","volume":"3","author":"MD Grounds","year":"2002","unstructured":"Grounds MD (2002) Reasons for the degeneration of ageing skeletal muscle: a central role for IGF-1 signalling. Biogerontology 3:19\u201324","journal-title":"Biogerontology"},{"key":"9894_CR5","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.3390\/ijms11041509","volume":"11","author":"SJ Meng","year":"2010","unstructured":"Meng SJ, Yu LJ (2010) Oxidative stress, molecular inflammation and sarcopenia. Int J Mol Sci 11:1509\u20131526","journal-title":"Int J Mol Sci"},{"key":"9894_CR6","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1016\/j.cellsig.2011.07.013","volume":"23","author":"CA Goodman","year":"2011","unstructured":"Goodman CA, Mayhew DL, Hornberger TA (2011) Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass. Cell Signal 23:1896\u20131906","journal-title":"Cell Signal"},{"key":"9894_CR7","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.amjmed.2003.05.001","volume":"115","author":"R Roubenoff","year":"2003","unstructured":"Roubenoff R, Parise H, Payette HA, Abad LW, D\u2019Agostino R, Jacques PF, Wilson PW, Dinarello CA, Harris TB (2003) Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: The Framingham Heart Study. Am J Med 115:429\u2013435","journal-title":"Am J Med"},{"key":"9894_CR8","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s12020-012-9751-7","volume":"43","author":"JP Gumucio","year":"2013","unstructured":"Gumucio JP, Mendias CL (2013) Atrogin-1, MuRF-1, and sarcopenia. Endocrine 43:12\u201321","journal-title":"Endocrine"},{"key":"9894_CR9","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/nyas.12129","volume":"1287","author":"S Christakos","year":"2013","unstructured":"Christakos S, Hewison M, Gardner DG, Wagner CL, Sergeev IN, Rutten E, Pittas AG, Boland R, Ferrucci L, Bikle DD (2013) Vitamin D: beyond bone. Ann N Y Acad Sci 1287:45\u201358","journal-title":"Ann N Y Acad Sci"},{"key":"9894_CR10","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1016\/j.cellsig.2011.05.003","volume":"23","author":"Z Huang","year":"2011","unstructured":"Huang Z, Chen X, Chen D (2011) Myostatin:a novel insight into its role in metabolism, signal pathways and expression regulation. Cell Signall 23:1441\u20131446","journal-title":"Cell Signall"},{"key":"9894_CR11","doi-asserted-by":"crossref","first-page":"9306","DOI":"10.1073\/pnas.151270098","volume":"98","author":"SJ Lee","year":"2001","unstructured":"Lee SJ, McPherron AC (2001) Regulation of myostatin activity and muscle growth. Proc Natl Acad Sci U S A 98:9306\u20139311","journal-title":"Proc Natl Acad Sci U S A"},{"key":"9894_CR12","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.mce.2011.05.021","volume":"347","author":"RL Boland","year":"2011","unstructured":"Boland RL (2011) VDR activation of intracellular signaling pathways in skeletal muscle. Mol Cell Endocrinol 347:11\u201316","journal-title":"Mol Cell Endocrinol"},{"key":"9894_CR13","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.mam.2008.07.002","volume":"29","author":"L Ceglia","year":"2008","unstructured":"Ceglia L (2008) Vitamin D and skeletal muscle tissue and function. Mol Asp Med 29:407\u2013414","journal-title":"Mol Asp Med"},{"key":"9894_CR14","doi-asserted-by":"crossref","first-page":"5138","DOI":"10.1210\/en.2003-0502","volume":"144","author":"I Endo","year":"2003","unstructured":"Endo I, Inoue D, Mitsui T, Umaki Y, Akaike M, Yoshizawa T, Kato S, Matsumoto T (2003) Deletion of vitamin D receptor gene in mice results in abnormal skeletal muscle development with deregulated expression of myoregulatory transcription factors. Endocrinology 144:5138\u20135144","journal-title":"Endocrinology"},{"key":"9894_CR15","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1093\/jn\/133.2.374","volume":"133","author":"Y Song","year":"2003","unstructured":"Song Y, Kato S, Fleet JC (2003) Vitamin D receptor (VDR) knockout mice reveal VDR-independent regulation of intestinal calcium absorption and ECaC2 and calbindin D9k mRNA. J Nutr 133:374\u2013380","journal-title":"J Nutr"},{"key":"9894_CR16","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1093\/gerona\/59.1.B10","volume":"59","author":"SM Roth","year":"2004","unstructured":"Roth SM, Zmuda JM, Cauley JA, Shea PR, Ferrell RE (2004) Vitamin D receptor genotype is associated with fat-free mass and sarcopenia in elderly men. J Gerontol A Biol Sci Med Sci 59:10\u201315","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"9894_CR17","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/387083a0","volume":"387","author":"AC McPherron","year":"1997","unstructured":"McPherron AC, Lawler AM, Lee SJ (1997) Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387:83\u201390","journal-title":"Nature"},{"key":"9894_CR18","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1101\/gr.7.9.910","volume":"7","author":"R Kambadur","year":"1997","unstructured":"Kambadur R, Sharma M, Smith TP, Bass JJ (1997) Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle. Genome Res 7:910\u2013916","journal-title":"Genome Res"},{"key":"9894_CR19","doi-asserted-by":"crossref","first-page":"3883","DOI":"10.1113\/jphysiol.2011.206193","volume":"589","author":"D Constantin","year":"2011","unstructured":"Constantin D, McCullough J, Mahajan RP, Greenhaff PL (2011) Novel events in the molecular regulation of muscle mass in critically ill patients. J Physiol 589:3883\u20133895","journal-title":"J Physiol"},{"key":"9894_CR20","doi-asserted-by":"crossref","first-page":"14938","DOI":"10.1073\/pnas.95.25.14938","volume":"95","author":"NF Gonzalez-Cadavid","year":"1998","unstructured":"Gonzalez-Cadavid NF, Taylor WE, Yarasheski K, Sinha-Hikim I, Ma K, Ezzat S, Shen R, Lalani R, Asa S, Mamita M, Nair G, Arver S, Bhasin S (1998) Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting. Proc Natl Acad Sci U S A 95:14938\u201314943","journal-title":"Proc Natl Acad Sci U S A"},{"key":"9894_CR21","doi-asserted-by":"crossref","first-page":"C124","DOI":"10.1152\/ajpcell.00142.2010","volume":"300","author":"DL Allen","year":"2011","unstructured":"Allen DL, Loh AS (2011) Posttranscriptional mechanisms involving microRNA-27a and b contribute to fast-specific and glucocorticoid-mediated myostatin expression in skeletal muscle. Am J Physiol Cell Physiol 300:C124\u2013C137","journal-title":"Am J Physiol Cell Physiol"},{"key":"9894_CR22","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1042\/BJ20112024","volume":"446","author":"S Lokireddy","year":"2012","unstructured":"Lokireddy S, Wijesoma IW, Bonala S, Wei M, Sze SK, McFarlane C, Kambadur R, Sharma M (2012) Myostatin is a novel tumoral factor that induces cancer cachexia. Biochem J 446:23\u201336","journal-title":"Biochem J"},{"key":"9894_CR23","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/MCO.0b013e32834dd297","volume":"15","author":"I Beyer","year":"2012","unstructured":"Beyer I, Mets T, Bautmans I (2012) Chronic low-grade inflammation and age-related sarcopenia. Curr Opin Clin Nutr Metab Care 15:12\u201322","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"9894_CR24","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1093\/gerona\/glp097","volume":"64","author":"LA Schaap","year":"2009","unstructured":"Schaap LA, Pluijm SM, Deeg DJ, Harris TB, Kritchevsky SB, Newman AB, Colbert LH, Pahor M, Rubin SM, Tylavsky FA, Visser M (2009) Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength. J Gerontol A Biol Sci Med Sci 64:1183\u20131189","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"9894_CR25","doi-asserted-by":"crossref","first-page":"M326","DOI":"10.1093\/gerona\/57.5.M326","volume":"57","author":"M Visser","year":"2002","unstructured":"Visser M, Pahor M, Taaffe DR, Goodpaster BH, Simonsick EM, Newman AB, Nevitt M, Harris TB (2002) Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: The Health ABC Study. J Gerontol A Biol Sci Med Sci 57:M326\u2013M332","journal-title":"J Gerontol A Biol Sci Med Sci"},{"issue":"53C","key":"9894_CR26","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.biocel.2014.04.025","volume":"13","author":"M Barns","year":"2014","unstructured":"Barns M, Gondro C, Tellam RL, Radley-Crabb HG, Grounds MD, Shavlakadze T (2014) Molecular analyses provide insight into mechanisms underlying sarcopenia and myofiber denervation in old skeletal muscles of mice. Int J Biochem Cell Biol 13(53C):174\u2013185","journal-title":"Int J Biochem Cell Biol"},{"key":"9894_CR27","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1093\/gerona\/glt015","volume":"68","author":"D Liu","year":"2013","unstructured":"Liu D, Sartor MA, Nader GA, Pistilli EE, Tanton L, Lilly C, Gutmann L, IglayReger HB, Visich PS, Hoffman EP, Gordon PM (2013) Microarray analysis reveals novel features of the muscle aging process in men and women. J Gerontol A Biol Sci Med Sci 68:1035\u20131044","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"9894_CR28","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/1471-2318-10-43","volume":"10","author":"HP Patel","year":"2010","unstructured":"Patel HP, Syddall HE, Martin HJ, Stewart CE, Cooper C, Sayer AA (2010) Hertfordshire Sarcopenia Study: design and methods. BMC Geriatr 10:43","journal-title":"BMC Geriatr"},{"key":"9894_CR29","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1093\/ije\/dyi127","volume":"34","author":"HE Syddall","year":"2005","unstructured":"Syddall HE, Sayer AA, Dennison EM, Martin HJ, Barker DJ, Cooper C (2005) Cohort profile: The Hertfordshire cohort study. Int J Epidemiol 34:1234\u20131242","journal-title":"Int J Epidemiol"},{"key":"9894_CR30","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402\u2013408","journal-title":"Methods"},{"key":"9894_CR31","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.cmpb.2005.12.002","volume":"82","author":"A Tichopad","year":"2006","unstructured":"Tichopad A, Pecen L, Pfaffl MW (2006) Distribution-insensitive cluster analysis in SAS on real-time PCR gene expression data of steadily expressed genes. Comput Methods Progr Biomed 82:44\u201350","journal-title":"Comput Methods Progr Biomed"},{"key":"9894_CR32","doi-asserted-by":"crossref","first-page":"W169","DOI":"10.1093\/nar\/gkm415","volume":"35","author":"DW Huang","year":"2007","unstructured":"Huang DW, Sherman BT, Tan Q, Kir J, Liu D, Bryant D, Guo Y, Stephens R, Baseler MW, Lane HC, Lempicki RA (2007) DAVID bioinformatics resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res 35:W169\u2013W175","journal-title":"Nucleic Acids Res"},{"key":"9894_CR33","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1093\/gerona\/61.10.1059","volume":"61","author":"BH Goodpaster","year":"2006","unstructured":"Goodpaster BH, Park SW, Harris TB, Kritchevsky SB, Nevitt M, Schwartz AV, Simonsick EM, Tylavsky FA, Visser M, Newman AB (2006) The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci 61:1059\u20131064","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"9894_CR34","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1089\/rej.2007.0588","volume":"11","author":"B Leger","year":"2008","unstructured":"Leger B, Derave W, De BK, Hespel P, Russell AP (2008) Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation. Rejuvenation Res 11:163\u2013175B","journal-title":"Rejuvenation Res"},{"key":"9894_CR35","doi-asserted-by":"crossref","first-page":"5483","DOI":"10.1113\/jphysiol.2009.178319","volume":"587","author":"I Rieu","year":"2009","unstructured":"Rieu I, Magne H, Savary-Auzeloux I, Averous J, Bos C, Peyron MA, Combaret L, Dardevet D (2009) Reduction of low grade inflammation restores blunting of postprandial muscle anabolism and limits sarcopenia in old rats. J Physiol 587:5483\u20135492","journal-title":"J Physiol"},{"key":"9894_CR36","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1111\/j.1532-5415.2011.03833.x","volume":"60","author":"B Bartali","year":"2012","unstructured":"Bartali B, Frongillo EA, Stipanuk MH, Bandinelli S, Salvini S, Palli D, Morais JA, Volpato S, Guralnik JM, Ferrucci L (2012) Protein intake and muscle strength in older persons: does inflammation matter? J Am Geriatr Soc 60:480\u2013484","journal-title":"J Am Geriatr Soc"},{"key":"9894_CR37","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1128\/MCB.05397-11","volume":"31","author":"P Londhe","year":"2011","unstructured":"Londhe P, Davie JK (2011) Gamma interferon modulates myogenesis through the major histocompatibility complex class II transactivator, CIITA. Mol Cell Biol 31:2854\u20132866","journal-title":"Mol Cell Biol"},{"key":"9894_CR38","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1189\/jlb.0603252","volume":"75","author":"K Schroder","year":"2004","unstructured":"Schroder K, Hertzog PJ, Ravasi T, Hume DA (2004) Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol 75:163\u2013189","journal-title":"J Leukoc Biol"},{"key":"9894_CR39","doi-asserted-by":"crossref","first-page":"C1183","DOI":"10.1152\/ajpcell.00568.2007","volume":"294","author":"M Cheng","year":"2008","unstructured":"Cheng M, Nguyen MH, Fantuzzi G, Koh TJ (2008) Endogenous interferon-gamma is required for efficient skeletal muscle regeneration. Am J Physiol Cell Physiol 294:C1183\u2013C1191","journal-title":"Am J Physiol Cell Physiol"},{"key":"9894_CR40","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1136\/thx.2007.078030","volume":"63","author":"E Barreiro","year":"2008","unstructured":"Barreiro E, Schols AM, Polkey MI, Galdiz JB, Gosker HR, Swallow EB, Coronell C, Gea J (2008) Cytokine profile in quadriceps muscles of patients with severe COPD. Thorax 63:100\u2013107","journal-title":"Thorax"},{"key":"9894_CR41","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1097\/BOR.0b013e32834b41d2","volume":"23","author":"S Rayavarapu","year":"2011","unstructured":"Rayavarapu S, Coley W, Nagaraju K (2011) An update on pathogenic mechanisms of inflammatory myopathies. Curr Opin Rheumatol 23:579\u2013584","journal-title":"Curr Opin Rheumatol"},{"key":"9894_CR42","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.ejcb.2011.09.011","volume":"91","author":"C Crescioli","year":"2012","unstructured":"Crescioli C, Sottili M, Bonini P, Cosmi L, Chiarugi P, Romagnani P, Vannelli GB, Colletti M, Isidori AM, Serio M, Lenzi A, Di LL (2012) Inflammatory response in human skeletal muscle cells: CXCL10 as a potential therapeutic target. Eur J Cell Biol 91:139\u2013149","journal-title":"Eur J Cell Biol"},{"key":"9894_CR43","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1161\/CIRCULATIONAHA.111.032680","volume":"124","author":"S Chen","year":"2011","unstructured":"Chen S, Law CS, Grigsby CL, Olsen K, Hong TT, Zhang Y, Yeghiazarians Y, Gardner DG (2011) Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy. Circulation 124:1838\u20131847","journal-title":"Circulation"},{"key":"9894_CR44","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1111\/j.1365-2265.2011.04120.x","volume":"75","author":"DS Han","year":"2011","unstructured":"Han DS, Chen YM, Lin SY, Chang HH, Huang TM, Chi YC, Yang WS (2011) Serum myostatin levels and grip strength in normal subjects and patients on maintenance haemodialysis. Clin Endocrinol (Oxf) 75:857\u2013863","journal-title":"Clin Endocrinol (Oxf)"},{"key":"9894_CR45","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/S0006-291X(02)02953-4","volume":"300","author":"LA Whittemore","year":"2003","unstructured":"Whittemore LA, Song K, Li X, Aghajanian J, Davies M, Girgenrath S, Hill JJ, Jalenak M, Kelley P, Knight A, Maylor R, O\u2019Hara D, Pearson A, Quazi A, Ryerson S, Tan XY, Tomkinson KN, Veldman GM, Widom A, Wright JF, Wudyka S, Zhao L, Wolfman NM (2003) Inhibition of myostatin in adult mice increases skeletal muscle mass and strength. Biochem Biophys Res Commun 300:965\u2013971","journal-title":"Biochem Biophys Res Commun"},{"key":"9894_CR46","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1073\/pnas.0604893104","volume":"104","author":"H Amthor","year":"2007","unstructured":"Amthor H, Macharia R, Navarrete R, Schuelke M, Brown SC, Otto A, Voit T, Muntoni F, Vrbova G, Partridge T, Zammit P, Bunger L, Patel K (2007) Lack of myostatin results in excessive muscle growth but impaired force generation. Proc Natl Acad Sci U S A 104:1835\u20131840","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"9894_CR47","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.exger.2012.11.008","volume":"48","author":"E Schirwis","year":"2012","unstructured":"Schirwis E, Agbulut O, Vadrot N, Mouisel E, Hourde C, Bonnieu A, Butler-Browne G, Amthor H, Ferry A (2012) The beneficial effect of myostatin deficiency on maximal muscle force and power is attenuated with age. Exp Gerontol 48(2):183\u2013190","journal-title":"Exp Gerontol"}],"container-title":["Calcified Tissue International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00223-014-9894-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00223-014-9894-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00223-014-9894-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T23:08:03Z","timestamp":1565651283000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00223-014-9894-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,24]]},"references-count":47,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["9894"],"URL":"https:\/\/doi.org\/10.1007\/s00223-014-9894-z","relation":{},"ISSN":["0171-967X","1432-0827"],"issn-type":[{"value":"0171-967X","type":"print"},{"value":"1432-0827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,24]]}}}