{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T00:39:45Z","timestamp":1784335185901,"version":"3.55.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2015,12,19]],"date-time":"2015-12-19T00:00:00Z","timestamp":1450483200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"National Research Foundation of Korea (NRF) grant funded by the Korean Government (MEST)","award":["2012R1A5A2051384"],"award-info":[{"award-number":["2012R1A5A2051384"]}]},{"name":"Korean Health Technology R&D Project","award":["HI14C0175"],"award-info":[{"award-number":["HI14C0175"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Calcif Tissue Int"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1007\/s00223-015-0095-1","type":"journal-article","created":{"date-parts":[[2015,12,18]],"date-time":"2015-12-18T23:46:06Z","timestamp":1450482366000},"page":"497-510","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Expression of Caveolin-1 in Periodontal Tissue and Its Role in Osteoblastic and Cementoblastic Differentiation In Vitro"],"prefix":"10.1007","volume":"98","author":[{"given":"So-Youn","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Kyu","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung-Mun","family":"Yun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheol-Hyeon","family":"Bae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eui-Sic","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kook-Sun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Cheol","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,12,19]]},"reference":[{"key":"95_CR1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.5051\/jpis.2011.41.4.167","volume":"41","author":"MH Choi","year":"2011","unstructured":"Choi MH, Noh WC, Park JW, Lee JM, Suh JY (2011) Gene expression pattern during osteogenic differentiation of human periodontal ligament cells in vitro. J Periodontal Implant Sci 41:167\u2013175","journal-title":"J Periodontal Implant Sci"},{"key":"95_CR2","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.archoralbio.2010.11.001","volume":"56","author":"A Mamalis","year":"2011","unstructured":"Mamalis A, Markopoulou C, Lagou A, Vrotsos I (2011) Oestrogen regulates proliferation, osteoblastic differentiation, collagen synthesis and periostin gene expression in human periodontal ligament cells through oestrogen receptor beta. Arch Oral Biol 56:446\u2013455","journal-title":"Arch Oral Biol"},{"key":"95_CR3","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s00441-005-0101-4","volume":"324","author":"S Fujii","year":"2006","unstructured":"Fujii S, Maeda H, Wada N, Kano Y, Akamine A (2006) Establishing and characterizing human periodontal ligament fibroblasts immortalized by SV40T-antigen and hTERT gene transfer. Cell Tissue Res 324:117\u2013125","journal-title":"Cell Tissue Res"},{"key":"95_CR4","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.cellbi.2004.06.004","volume":"28","author":"WP Xu","year":"2004","unstructured":"Xu WP, Shiba H, Mizuno N, Uchida Y, Mouri Y, Kawaguchi H, Kurihara H (2004) Effect of bone morphogenetic proteins-4, -5 and -6 on DNA synthesis and expression of bone-related proteins in cultured human periodontal ligament cells. Cell Biol Int 28:675\u2013682","journal-title":"Cell Biol Int"},{"key":"95_CR5","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.archoralbio.2011.12.003","volume":"57","author":"T Hidaka","year":"2012","unstructured":"Hidaka T, Nagasawa T, Shirai K, Kado T, Furuichi Y (2012) FGF-2 induces proliferation of human periodontal ligament cells and maintains differentiation potentials of STRO-1(+)\/CD146(+) periodontal ligament cells. Arch Oral Biol 57:830\u2013840","journal-title":"Arch Oral Biol"},{"key":"95_CR6","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s00418-011-0908-x","volume":"137","author":"Y Yu","year":"2012","unstructured":"Yu Y, Mu J, Fan Z, Lei G, Yan M, Wang S, Tang C, Wang Z, Yu J, Zhang G (2012) Insulin-like growth factor 1 enhances the proliferation and osteogenic differentiation of human periodontal ligament stem cells via ERK and JNK MAPK pathways. Histochem Cell Biol 137:513\u2013525","journal-title":"Histochem Cell Biol"},{"key":"95_CR7","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s00441-012-1392-x","volume":"348","author":"JH Lee","year":"2012","unstructured":"Lee JH, Um S, Jang JH, Seo BM (2012) Effects of VEGF and FGF-2 on proliferation and differentiation of human periodontal ligament stem cells. Cell Tissue Res 348:475\u2013484","journal-title":"Cell Tissue Res"},{"key":"95_CR8","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/jre.12136","volume":"49","author":"JH Chung","year":"2014","unstructured":"Chung JH, Kim YS, Noh K, Lee YM, Chang SW, Kim EC (2014) Deferoxamine promotes osteoblastic differentiation in human periodontal ligament cells via the nuclear factor erythroid 2-related factor-mediated antioxidant signaling pathway. J Periodontal Res 49:563\u2013573","journal-title":"J Periodontal Res"},{"key":"95_CR9","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1248\/bpb.32.1328","volume":"32","author":"SK Lee","year":"2009","unstructured":"Lee SK, Choi HI, Yang YS, Jeong GS, Hwang JH, Lee SI, Kang KH, Cho JH, Chae JM, Lee SK, Kim YC, Kim EC (2009) Nitric oxide modulates osteoblastic differentiation with heme oxygenase-1 via the mitogen activated protein kinase and nuclear factor-kappaB pathways in human periodontal ligament cells. Biol Pharm Bull 32:1328\u20131334","journal-title":"Biol Pharm Bull"},{"key":"95_CR10","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.cellbi.2008.12.007","volume":"33","author":"YA Kook","year":"2009","unstructured":"Kook YA, Lee SK, Son DH, Kim Y, Kang KH, Cho JH, Kim SC, Kim YS, Lee HJ, Lee SK, Kim EC (2009) Effects of substance P on osteoblastic differentiation and heme oxygenase-1 in human periodontal ligament cells. Cell Biol Int 33:424\u2013428","journal-title":"Cell Biol Int"},{"key":"95_CR11","first-page":"552","volume":"80","author":"JH Cho","year":"2010","unstructured":"Cho JH, Lee SK, Lee JW, Kim EC (2010) The role of heme oxygenase-1 in mechanical stress-and lipopolysaccharide-induced osteogenic differentiation in human periodontal ligament cells. Angle Orthod 80:552\u2013559","journal-title":"Angle Orthod"},{"key":"95_CR12","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1111\/j.1600-0765.2011.01394.x","volume":"46","author":"YM Lee","year":"2011","unstructured":"Lee YM, Shin SI, Shin KS, Lee YR, Park BH, Kim EC (2011) The role of sirtuin 1 in osteoblastic differentiation in human periodontal ligament cells. J Periodontal 46:712\u2013721","journal-title":"J Periodontal"},{"key":"95_CR13","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1302\/0301-620X.83B1.10604","volume":"83","author":"RA Lofthouse","year":"2001","unstructured":"Lofthouse RA, Davis JR, Frondoza CG, Jinnah RH, Hungerford DS, Hare JM (2001) Identification of caveolae and detection of caveolin in normal human osteoblasts. J Bone Joint Surg 83:124\u2013129","journal-title":"J Bone Joint Surg"},{"key":"95_CR14","doi-asserted-by":"crossref","first-page":"L775","DOI":"10.1152\/ajplung.00327.2009","volume":"298","author":"Y Wang","year":"2010","unstructured":"Wang Y, Maciejewski BS, Drouillard D, Santos M, Hokenson MA, Hawwa RL, Huang Z, Sanchez-Esteban J (2010) A role for caveolin-1 in mechanotransduction of fetal type II epithelial cells. J Physiol Lung Cell Mol Physiol 298:L775\u2013L783","journal-title":"J Physiol Lung Cell Mol Physiol"},{"key":"95_CR15","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/jcp.21517","volume":"217","author":"T Yamaguchi","year":"2008","unstructured":"Yamaguchi T, Naruishi K, Arai H, Nishimura F, Takashiba S (2008) IL-6\/sIL-6R enhances cathepsin B and L production via caveolin-1-mediated JNK-AP-1 pathway in human gingival fibroblasts. J Cell Physiol 217:423\u2013432","journal-title":"J Cell Physiol"},{"key":"95_CR16","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1359\/jbmr.2000.15.12.2391","volume":"15","author":"KR Solomon","year":"2000","unstructured":"Solomon KR, Adolphson LD, Wank DA, McHugh KP, Hauschka PV (2000) Caveolae in human and murine osteoblasts. J Bone Miner Res 15:2391\u20132401","journal-title":"J Bone Miner Res"},{"key":"95_CR17","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1359\/jbmr.2000.15.12.2380","volume":"15","author":"KR Solomon","year":"2000","unstructured":"Solomon KR, Danciu TE, Adolphson LD, Hecht LE, Hauschka PV (2000) Caveolin-enriched membrane signaling complexes in human and murine osteoblasts. J Bone Miner Res 15:2380\u20132390","journal-title":"J Bone Miner Res"},{"key":"95_CR18","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1242\/jcs.01402","volume":"118","author":"A Nohe","year":"2005","unstructured":"Nohe A, Keating E, Underhill TM, Knaus P, Petersen NO (2005) Dynamics and interaction of caveolin-1 isoforms with BMP-receptors. J Cell Sci 118:643\u2013650","journal-title":"J Cell Sci"},{"key":"95_CR19","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.bone.2007.02.030","volume":"41","author":"N Sawada","year":"2007","unstructured":"Sawada N, Taketani Y, Amizuka N, Ichikawa M, Ogawa C, Nomoto K, Nashiki K, Sato T, Arai H, Isshiki M, Segawa H, Yamamoto H, Miyamoto K, Takeda E (2007) Caveolin-1 in extracellular matrix vesicles secreted from osteoblasts. Bone 41:52\u201358","journal-title":"Bone"},{"key":"95_CR20","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.4161\/cc.4.12.2198","volume":"4","author":"F Sotgia","year":"2005","unstructured":"Sotgia F, Williams TM, Cohen AW, Minetti C, Pestell RG, Lisanti MP (2005) Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt\/beta-catenin signaling. Cell Cycle 4:1808\u20131816","journal-title":"Cell Cycle"},{"key":"95_CR21","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1359\/jbmr.070601","volume":"22","author":"J Rubin","year":"2007","unstructured":"Rubin J, Schwartz Z, Boyan BD, Fan X, Case N, Sen B, Drab M, Smith D, Aleman M, Wong KL, Yao H, Jo H, Gross TS (2007) Caveolin-1 knockout mice have increased bone size and stiffness. J Bone Miner Res 22:1408\u20131418","journal-title":"J Bone Miner Res"},{"key":"95_CR22","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/emm.2005.13","volume":"37","author":"SY Jung","year":"2005","unstructured":"Jung SY, Kwak JO, Kim HW, Kim DS, Ryu SD, Ko CB, Cha SH (2005) Calcium sensing receptor forms complex with and is up-regulated by caveolin-1 in cultured human osteosarcoma (Saos-2) cells. Exp Mol Med 37:91\u2013100","journal-title":"Exp Mol Med"},{"key":"95_CR23","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.bbrc.2006.08.142","volume":"349","author":"M Kitagawa","year":"2006","unstructured":"Kitagawa M, Kudo Y, Iizuka S, Ogawa I, Abiko Y, Miyauchi M, Takata T (2006) Effect of F-spondin on cementoblastic differentiation of human periodontal ligament cells. Biochem Biophys Res Commun 349:1050\u20131056","journal-title":"Biochem Biophys Res Commun"},{"key":"95_CR24","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.bone.2006.07.003","volume":"40","author":"T Hayami","year":"2007","unstructured":"Hayami T, Zhang Q, Kapila Y, Kapila S (2007) Dexamethasone\u2019s enhancement of osteoblastic markers in human periodontal ligament cells is associated with inhibition of collagenase expression. Bone 40:93\u2013104","journal-title":"Bone"},{"key":"95_CR25","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1002\/path.1536","volume":"202","author":"F Afzal","year":"2004","unstructured":"Afzal F, Polak J, Buttery L (2004) Endothelial nitric oxide synthase in the control of osteoblastic mineralizing activity and bone integrity. J Pathol 202:503\u2013510","journal-title":"J Pathol"},{"key":"95_CR26","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s00441-010-1111-4","volume":"343","author":"I Brun-Heath","year":"2011","unstructured":"Brun-Heath I, Ermonval M, Chabrol E, Xiao J, Palkovits M, Lyck R, Miller F, Couraud PO, Mornet E, Fonta C (2011) Differential expression of the bone and the liver tissue non-specific alkaline phosphatase isoforms in brain tissues. Cell Tissue Res 343:521\u2013536","journal-title":"Cell Tissue Res"},{"key":"95_CR27","doi-asserted-by":"crossref","first-page":"E139","DOI":"10.1152\/ajpendo.90677.2008","volume":"296","author":"I Kanazawa","year":"2009","unstructured":"Kanazawa I, Yamaguchi T, Yano S, Yamauchi M, Sugimoto T (2009) Activation of AMP kinase and inhibition of Rho kinase induce the mineralization of osteoblastic MC3T3-E1 cells through endothelial NOS and BMP-2 expression. Am J Physiol Endocrinol Metab 296:E139\u2013E146","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"24","key":"95_CR28","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1034\/j.1600-0757.2000.2240105.x","volume":"2000","author":"NE Saygin","year":"2000","unstructured":"Saygin NE, Giannobile WV, Somerman MJ (2000) Molecular and cell biology of cementum. Periodontol 2000(24):73\u201398","journal-title":"Periodontol"},{"key":"95_CR29","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1034\/j.1600-0757.2000.2240106.x","volume":"24","author":"J Sodek","year":"2000","unstructured":"Sodek J (2000) McKee MD (2000) Molecular and cellular biology of alveolar bone. Periodontol 24:99\u2013126","journal-title":"Periodontol"},{"key":"95_CR30","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/j.1469-7580.2008.01029.x","volume":"214","author":"N Iizuka","year":"2009","unstructured":"Iizuka N, Suzuki A, Nozawa-Inoue K, Kawano Y, Nandasena BG, Okiji T, Maeda T (2009) Differential cell-specific location of Cav-1 and Ca(2+)-ATPase in terminal Schwann cells and mechanoreceptive Ruffini endings in the periodontal ligament of the rat incisor. J Anat 214:267\u2013274","journal-title":"J Anat"},{"key":"95_CR31","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1083\/jcb.200402046","volume":"165","author":"M Murshed","year":"2009","unstructured":"Murshed M, Schinke T, McKee MD, Karsenty G (2009) Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins. J Cell Biol 165:625\u2013630","journal-title":"J Cell Biol"},{"key":"95_CR32","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1002\/(SICI)1097-0177(199703)208:3<432::AID-AJA13>3.0.CO;2-1","volume":"208","author":"S Narisawa","year":"1997","unstructured":"Narisawa S, Fr\u00f6hlander N, Mill\u00e1n JL (1997) Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia. Dev Dyn 208:432\u2013446","journal-title":"Dev Dyn"},{"key":"95_CR33","doi-asserted-by":"crossref","first-page":"3773","DOI":"10.1002\/jcb.24252","volume":"113","author":"N Baker","year":"2012","unstructured":"Baker N, Zhang G, You Y, Tuan RS (2012) Caveolin-1 regulates proliferation and osteogenic differentiation of human mesenchymal stem cells. J Cell Biochem 113:3773\u20133787","journal-title":"J Cell Biochem"},{"key":"95_CR34","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s12964-014-0057-7","volume":"12","author":"J Rey-Barroso","year":"2014","unstructured":"Rey-Barroso J, Alvarez-Barrientos A, Rico-Leo E, Contador-Troca M, Carvajal-Gonzalez JM, Echarri A, Del Pozo MA, Fernandez-Salguero PM (2014) The Dioxin receptor modulates Caveolin-1 mobilization during directional migration: role of cholesterol. Cell Commun Signal 12:57\u201376","journal-title":"Cell Commun Signal"},{"key":"95_CR35","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.archoralbio.2007.12.011","volume":"53","author":"L Liang","year":"2008","unstructured":"Liang L, Yu JF, Wang Y, Wang G, Ding Y (2008) Effect of estrogen receptor beta on the osteoblastic differentiation function of human periodontal ligament cells. Arch Oral Biol 53:553\u2013557","journal-title":"Arch Oral Biol"},{"key":"95_CR36","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.ejcb.2011.12.005","volume":"91","author":"K Diercke","year":"2012","unstructured":"Diercke K, K\u00f6nig A, Kohl A, Lux CJ, Erber R (2012) Human primary cementoblasts respond to combined IL-1\u03b2 stimulation and compression with an impaired BSP and CEMP-1 expression. Eur J Cell Biol 91:402\u2013412","journal-title":"Eur J Cell Biol"},{"key":"95_CR37","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/00002281-199505000-00016","volume":"7","author":"C Cormier","year":"1995","unstructured":"Cormier C (1995) Markers of bone metabolism. Curr Opin Rheumatol 7:243\u2013248","journal-title":"Curr Opin Rheumatol"},{"key":"95_CR38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2220\/biomedres.34.1","volume":"34","author":"N Takizawa","year":"2013","unstructured":"Takizawa N, Sawada S, Chosa N, Ishisaki A, Naruishi K (2013) Secreted caveolin-1 enhances periodontal inflammation by targeting gingival fibroblasts. Biomed Res 34:1\u201311","journal-title":"Biomed Res"},{"key":"95_CR39","doi-asserted-by":"crossref","first-page":"G375","DOI":"10.1152\/ajpgi.00343.2009","volume":"298","author":"M Anitha","year":"2010","unstructured":"Anitha M, Shahnavaz N, Qayed E, Joseph I, Gossrau G, Mwangi S, Sitaraman SV, Greene JG, Srinivasan S (2010) BMP2 promotes differentiation of nitrergic and catecholaminergic enteric neurons through a Smad1-dependent pathway. Am J Physiol Gastrointest Liver Physiol 298:G375\u2013G383","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"95_CR40","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/s00223-005-0146-0","volume":"78","author":"C Morsczeck","year":"2006","unstructured":"Morsczeck C (2006) Gene expression of runx2, Osterix, c-fos, DLX-3, DLX-5, and MSX-2 in dental follicle cells during osteogenic differentiation in vitro. Calcif Tissue Int 78:98\u2013102","journal-title":"Calcif Tissue Int"},{"key":"95_CR41","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1126\/science.1071549","volume":"296","author":"RT Moon","year":"2002","unstructured":"Moon RT, Bowerman B, Boutros M, Perrimon N (2002) The promise and perils of wnt signaling through beta-catenin. Science 296:1644\u20131646","journal-title":"Science"},{"issue":"12","key":"95_CR42","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.4161\/cc.4.12.2198","volume":"4","author":"F Sotgia","year":"2005","unstructured":"Sotgia F, Williams TM, Cohen AW, Minetti C, Pestell RG, Lisanti MP (2005) Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt\/beta-catenin signaling. Cell Cycle 4(12):1808\u20131816","journal-title":"Cell Cycle"},{"key":"95_CR43","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1089\/ten.2006.12.257","volume":"12","author":"B Inanc","year":"2006","unstructured":"Inanc B, Elcin AE, Elcin YM (2006) Osteogenic induction of human periodontal ligament fibroblasts under two- and three-dimensional culture conditions. Tissue Eng 12:257\u2013266","journal-title":"Tissue Eng"},{"key":"95_CR44","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/1471-2121-8-51","volume":"8","author":"I Kanazawa","year":"2007","unstructured":"Kanazawa I, Yamaguchi T, Yano S, Yamauchi M, Yamamoto M, Sugimoto T (2007) Adiponectin and AMP kinase activator stimulate proliferation, differentiation, and mineralization of osteoblastic MC3T3\u2013E1 cells. BMC Cell Biol 8:51\u201362","journal-title":"BMC Cell Biol"},{"key":"95_CR45","doi-asserted-by":"crossref","first-page":"33902","DOI":"10.1074\/jbc.M802537200","volume":"283","author":"N Horike","year":"2008","unstructured":"Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T (2008) AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver. J Biol Chem 283:33902\u201333910","journal-title":"J Biol Chem"},{"key":"95_CR46","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.bone.2011.10.028","volume":"50","author":"N Hada","year":"2012","unstructured":"Hada N, Okayasu M, Ito J, Nakayachi M, Hayashida C, Kaneda T, Uchida N, Muramatsu T, Koike C, Masuhara M, Sato T, Hakeda Y (2012) Receptor activator of NF-\u03baB ligand-dependent expression of caveolin-1 in osteoclast precursors, and high dependency of osteoclastogenesis on exogenous lipoprotein. Bone 50:226\u2013236","journal-title":"Bone"},{"key":"95_CR47","doi-asserted-by":"crossref","first-page":"C935","DOI":"10.1152\/ajpcell.00121.2009","volume":"297","author":"JH Park","year":"2009","unstructured":"Park JH, Han HJ (2009) Caveolin-1 plays important role in EGF-induced migration and proliferation of mouse embryonic stem cells: involvement of PI3\u00a0K\/Akt and ERK. Am J Physiol Cell Physiol 297:C935\u2013C944","journal-title":"Am J Physiol Cell Physiol"}],"container-title":["Calcified Tissue International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00223-015-0095-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00223-015-0095-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00223-015-0095-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T14:48:34Z","timestamp":1567435714000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00223-015-0095-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,19]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["95"],"URL":"https:\/\/doi.org\/10.1007\/s00223-015-0095-1","relation":{},"ISSN":["0171-967X","1432-0827"],"issn-type":[{"value":"0171-967X","type":"print"},{"value":"1432-0827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,19]]}}}