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Piot, I. Plotton, S. Boutroy, J. Bacchetta, S. Ailloud, H. Lejeune, R. D. Chapurlat, P. Szulc and C. B. Confavreux declare that they have no conflict of interest concerning this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"It has been approved by the local ethics committee \u201cComit\u00e9 de Protection des Personnes Lyon Sud-Est II\u2014CHU de Lyon, France\u201d (study number 2010-017-2 on June 17th 2010 with amendments on September 9th 2015 and October 10th 2017). 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