{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T09:59:36Z","timestamp":1789639176093,"version":"4.0.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T00:00:00Z","timestamp":1711411200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T00:00:00Z","timestamp":1711411200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100002429","name":"Amgen","doi-asserted-by":"publisher","award":["307925+307926"],"award-info":[{"award-number":["307925+307926"]}],"id":[{"id":"10.13039\/100002429","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Calcif Tissue Int"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study evaluated the performance of a vertebral fracture detection algorithm (HealthVCF) in a real-life setting and assessed the impact on treatment and diagnostic workflow. HealthVCF was used to identify moderate and severe vertebral compression fractures (VCF) at a Danish hospital. Around 10,000 CT scans were processed by the HealthVCF and CT scans positive for VCF formed both the baseline and 6-months follow-up cohort. To determine performance of the algorithm 1000 CT scans were evaluated by specialized radiographers to determine performance of the algorithm. Sensitivity was 0.68 (CI 0.581\u20130.776) and specificity 0.91 (CI 0.89\u20130.928). At 6-months follow-up, 18% of the 538 patients in the retrospective cohort were dead, 78 patients had been referred for a DXA scan, while 25 patients had been diagnosed with osteoporosis. A higher mortality rate was seen in patients not known with osteoporosis at baseline compared to patients known with osteoporosis at baseline, 12.8% versus 22.6% (p\u2009=\u20090.003). Patients receiving bisphosphonates had a lower mortality rate (9.6%) compared to the rest of the population (20.9%) (p\u2009=\u20090.003). HealthVCF demonstrated a poorer performance than expected, and the tested version is not generalizable to the Danish population. Based on its specificity, the HealthVCF can be used as a tool to prioritize resources in opportunistic identification of VCF\u2019s. Implementing such a tool on its own only resulted in a small number of new diagnoses of osteoporosis and referrals to DXA scans during a 6-month follow-up period. To increase efficiency, the HealthVCF should be integrated with Fracture Liaison Services (FLS).<\/jats:p>","DOI":"10.1007\/s00223-024-01196-2","type":"journal-article","created":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T12:02:19Z","timestamp":1711454539000},"page":"468-479","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Opportunistic Identification of Vertebral Compression Fractures on CT Scans of the Chest and Abdomen, Using an AI Algorithm, in a Real-Life Setting"],"prefix":"10.1007","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4858-4186","authenticated-orcid":false,"given":"Magnus Gr\u00f8nlund","family":"Bendtsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2195-8552","authenticated-orcid":false,"given":"Mette Friberg","family":"Hitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,26]]},"reference":[{"issue":"1","key":"1196_CR1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00198-018-4704-5","volume":"30","author":"JA Kanis","year":"2019","unstructured":"Kanis JA, Cooper C, Rizzoli R, Reginster JY (2019) European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int 30(1):3\u201344. https:\/\/doi.org\/10.1007\/s00198-018-4704-5","journal-title":"Osteoporos Int"},{"issue":"2","key":"1196_CR2","doi-asserted-by":"publisher","first-page":"S12","DOI":"10.1016\/S0002-9343(97)90022-X","volume":"103","author":"C Cooper","year":"1997","unstructured":"Cooper C (1997) The crippling consequences of fractures and their impact on quality of life. Am J Med 103(2):S12\u2013S19. https:\/\/doi.org\/10.1016\/S0002-9343(97)90022-X","journal-title":"Am J Med"},{"issue":"11","key":"1196_CR3","doi-asserted-by":"publisher","first-page":"2611","DOI":"10.1002\/1529-0131(200111)44:11<2611::AID-ART441>3.0.CO;2-N","volume":"44","author":"SL Silverman","year":"2001","unstructured":"Silverman SL, Minshall ME, Shen W, Harper KD, Xie S (2001) The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis: results from the multiple outcomes of raloxifene evaluation study. Arthritis Rheum 44(11):2611\u20132619. https:\/\/doi.org\/10.1002\/1529-0131(200111)44:11%3c2611::AID-ART441%3e3.0.CO;2-N","journal-title":"Arthritis Rheum"},{"issue":"1","key":"1196_CR4","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s00256-013-1729-x","volume":"43","author":"A Venmans","year":"2014","unstructured":"Venmans A, Lohle PNM, Van Rooij WJ (2014) Pain course in conservatively treated patients with back pain and a VCF on the spine radiograph (VERTOS III). Skeletal Radiol 43(1):13\u201318. https:\/\/doi.org\/10.1007\/s00256-013-1729-x","journal-title":"Skeletal Radiol"},{"issue":"9","key":"1196_CR5","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1016\/j.jvir.2010.05.018","volume":"21","author":"CAH Klazen","year":"2010","unstructured":"Klazen CAH et al (2010) Clinical course of pain in acute osteoporotic vertebral compression fractures. J Vasc Interv Radiol 21(9):1405\u20131409. https:\/\/doi.org\/10.1016\/j.jvir.2010.05.018","journal-title":"J Vasc Interv Radiol"},{"issue":"2","key":"1196_CR6","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1007\/s00198-003-1516-y","volume":"15","author":"JA Kanis","year":"2004","unstructured":"Kanis JA, Oden A, Johnell O, De Laet C, Jonsson B (2004) Excess mortality after hospitalisation for vertebral fracture. Osteoporos Int 15(2):108\u2013112. https:\/\/doi.org\/10.1007\/s00198-003-1516-y","journal-title":"Osteoporos Int"},{"issue":"2","key":"1196_CR7","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/s00198-020-05602-x","volume":"32","author":"SB Lee","year":"2021","unstructured":"Lee SB et al (2021) Association between mortality risk and the number, location, and sequence of subsequent fractures in the elderly. Osteoporos Int 32(2):233\u2013241. https:\/\/doi.org\/10.1007\/s00198-020-05602-x","journal-title":"Osteoporos Int"},{"issue":"1","key":"1196_CR8","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1359\/jbmr.1999.14.1.90","volume":"14","author":"DM Black","year":"1999","unstructured":"Black DM, Palermo L, Nevitt MC, Genant HK, Christensen L, Cummings SR (1999) Defining incident vertebral deformity: a prospective comparison of several approaches. J Bone Miner Res 14(1):90\u2013101. https:\/\/doi.org\/10.1359\/jbmr.1999.14.1.90","journal-title":"J Bone Miner Res"},{"issue":"4","key":"1196_CR9","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1359\/jbmr.2000.15.4.721","volume":"15","author":"CM Klotzbuecher","year":"2000","unstructured":"Klotzbuecher CM, Ross PD, Landsman PB, Abbott TA, Berger M (2000) Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res 15(4):721\u2013739. https:\/\/doi.org\/10.1359\/jbmr.2000.15.4.721","journal-title":"J Bone Miner Res"},{"issue":"1","key":"1196_CR10","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/s00198-013-2460-0","volume":"25","author":"H Johansson","year":"2014","unstructured":"Johansson H, Od\u00e9n A, McCloskey EV, Kanis JA (2014) Mild morphometric vertebral fractures predict vertebral fractures but not non-vertebral fractures. Osteoporos Int 25(1):235\u2013241. https:\/\/doi.org\/10.1007\/s00198-013-2460-0","journal-title":"Osteoporos Int"},{"issue":"7","key":"1196_CR11","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1007\/s001980070078","volume":"11","author":"SH Gehlbach","year":"2000","unstructured":"Gehlbach SH, Bigelow C, Heimisdottir M, May S, Walker M, Kirkwood JR (2000) Recognition of vertebral fracture in a clinical setting. Osteoporos Int 11(7):577\u2013582. https:\/\/doi.org\/10.1007\/s001980070078","journal-title":"Osteoporos Int"},{"issue":"4","key":"1196_CR12","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1359\/JBMR.041214","volume":"20","author":"PD Delmas","year":"2005","unstructured":"Delmas PD et al (2005) Underdiagnosis of vertebral fractures is a worldwide problem: the IMPACT study. J Bone Miner Res 20(4):557\u2013563. https:\/\/doi.org\/10.1359\/JBMR.041214","journal-title":"J Bone Miner Res"},{"issue":"3","key":"1196_CR13","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1007\/s00198-021-06169-x","volume":"33","author":"MT L\u00f6ffler","year":"2022","unstructured":"L\u00f6ffler MT et al (2022) Epidemiology and reporting of osteoporotic vertebral fractures in patients with long-term hospital records based on routine clinical CT imaging. Osteoporos Int 33(3):685\u2013694. https:\/\/doi.org\/10.1007\/s00198-021-06169-x","journal-title":"Osteoporos Int"},{"issue":"3","key":"1196_CR14","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1001\/jama.285.3.320","volume":"285","author":"R Lindsay","year":"2001","unstructured":"Lindsay R (2001) Risk of new vertebral fracture in the year following a fracture. J Am Med Assoc 285(3):320. https:\/\/doi.org\/10.1001\/jama.285.3.320","journal-title":"J Am Med Assoc"},{"issue":"3","key":"1196_CR15","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1007\/s00198-019-04852-8","volume":"30","author":"J Banefelt","year":"2019","unstructured":"Banefelt J et al (2019) Risk of imminent fracture following a previous fracture in a Swedish database study. Osteoporos Int 30(3):601\u2013609. https:\/\/doi.org\/10.1007\/s00198-019-04852-8","journal-title":"Osteoporos Int"},{"issue":"6","key":"1196_CR16","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1007\/s00198-020-05772-8","volume":"32","author":"L Iconaru","year":"2021","unstructured":"Iconaru L et al (2021) Risk factors for imminent fractures: a substudy of the FRISBEE cohort. Osteoporos Int 32(6):1093\u20131101. https:\/\/doi.org\/10.1007\/s00198-020-05772-8","journal-title":"Osteoporos Int"},{"issue":"7","key":"1196_CR17","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1002\/jbmr.5650110716","volume":"11","author":"HK Genant","year":"1996","unstructured":"Genant HK et al (1996) Comparison of semiquantitative visual and quantitative morphometric assessment of prevalent and incident vertebral fractures in osteoporosis. J Bone Miner Res 11(7):984\u2013996. https:\/\/doi.org\/10.1002\/jbmr.5650110716","journal-title":"J Bone Miner Res"},{"issue":"2","key":"1196_CR18","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.crad.2007.01.031","volume":"63","author":"EK Woo","year":"2008","unstructured":"Woo EK, Mansoubi H, Alyas F (2008) Incidental vertebral fractures on multidetector CT images of the chest: prevalence and recognition. Clin Radiol 63(2):160\u2013164. https:\/\/doi.org\/10.1016\/j.crad.2007.01.031","journal-title":"Clin Radiol"},{"issue":"1","key":"1196_CR19","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.ejrad.2007.08.028","volume":"69","author":"AL Williams","year":"2009","unstructured":"Williams AL, Al-Busaidi A, Sparrow PJ, Adams JE, Whitehouse RW (2009) Under-reporting of osteoporotic vertebral fractures on computed tomography. Eur J Radiol 69(1):179\u2013183. https:\/\/doi.org\/10.1016\/j.ejrad.2007.08.028","journal-title":"Eur J Radiol"},{"issue":"3","key":"1196_CR20","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/j.ejrad.2007.11.036","volume":"69","author":"T Bartalena","year":"2009","unstructured":"Bartalena T et al (2009) Prevalence of thoracolumbar vertebral fractures on multidetector CT. Underreporting by radiologists. Eur J Radiol 69(3):555\u2013559. https:\/\/doi.org\/10.1016\/j.ejrad.2007.11.036","journal-title":"Eur J Radiol"},{"key":"1196_CR21","doi-asserted-by":"publisher","unstructured":"Bar A, Wolf L, Bergman Amitai O, Toledano E, Elnekave E (2017) Compression fractures detection on CT. In: Medical imaging 2017: computer-aided diagnosis. SPIE, p 1013440. https:\/\/doi.org\/10.1117\/12.2249635","DOI":"10.1117\/12.2249635"},{"key":"1196_CR22","doi-asserted-by":"publisher","DOI":"10.1002\/jbm4.10778","author":"JH Page","year":"2023","unstructured":"Page JH, Moser FG, Maya MM, Prasad R, Pressman BD (2023) Opportunistic CT screening\u2014machine learning algorithm identifies majority of vertebral compression fractures: a cohort study. JBMR Plus. https:\/\/doi.org\/10.1002\/jbm4.10778","journal-title":"JBMR Plus"},{"issue":"12","key":"1196_CR23","doi-asserted-by":"publisher","first-page":"2307","DOI":"10.1002\/jbmr.4146","volume":"35","author":"N Kolanu","year":"2020","unstructured":"Kolanu N et al (2020) Clinical utility of computer-aided diagnosis of vertebral fractures from computed tomography images. J Bone Miner Res 35(12):2307\u20132312. https:\/\/doi.org\/10.1002\/jbmr.4146","journal-title":"J Bone Miner Res"},{"issue":"1","key":"1196_CR24","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1148\/radiol.220182","volume":"306","author":"SH Park","year":"2023","unstructured":"Park SH et al (2023) Methods for clinical evaluation of artificial intelligence algorithms for medical diagnosis. Radiology 306(1):20\u201331. https:\/\/doi.org\/10.1148\/radiol.220182","journal-title":"Radiology"},{"key":"1196_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/s2589-7500(19)30123-2","author":"X Liu","year":"2019","unstructured":"Liu X et al (2019) A comparison of deep learning performance against health-care professionals in detecting diseases from Medical Imaging: a systematic review and meta-analysis. Lancet Digit Health. https:\/\/doi.org\/10.1016\/s2589-7500(19)30123-2","journal-title":"Lancet Digit Health"},{"issue":"9","key":"1196_CR26","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1007\/s001980170046","volume":"12","author":"F Grados","year":"2001","unstructured":"Grados F, Roux C, de Vernejoul MC, Utard G, Sebert JL, Fardellone P (2001) Comparison of four morphometric definitions and a semiquantitative consensus reading for assessing prevalent vertebral fractures. Osteoporos Int 12(9):716\u2013722. https:\/\/doi.org\/10.1007\/s001980170046","journal-title":"Osteoporos Int"},{"issue":"10","key":"1196_CR27","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1359\/jbmr.060711","volume":"21","author":"JT Schousboe","year":"2006","unstructured":"Schousboe JT, Fink HA, Lui LY, Taylor BC, Ensrud KE (2006) Association between prior non-spine non-hip fractures or prevalent radiographic vertebral deformities known to be at least 10 years old and incident hip fracture. J Bone Miner Res 21(10):1557\u20131564. https:\/\/doi.org\/10.1359\/jbmr.060711","journal-title":"J Bone Miner Res"},{"issue":"3","key":"1196_CR28","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1002\/jbmr.1476","volume":"27","author":"S Gehlbach","year":"2012","unstructured":"Gehlbach S et al (2012) Previous fractures at multiple sites increase the risk for subsequent fractures: the global longitudinal study of osteoporosis in women. J Bone Miner Res 27(3):645\u2013653. https:\/\/doi.org\/10.1002\/jbmr.1476","journal-title":"J Bone Miner Res"},{"issue":"2","key":"1196_CR29","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1002\/jbmr.2028","volume":"29","author":"CF Buckens","year":"2014","unstructured":"Buckens CF, De Jong PA, Mali WP, Verhaar HJ, Van Der Graaf Y, Verkooijen HM (2014) Prevalent vertebral fractures on chest CT: higher risk for future hip fracture. J Bone Miner Res 29(2):392\u2013398. https:\/\/doi.org\/10.1002\/jbmr.2028","journal-title":"J Bone Miner Res"},{"issue":"5","key":"1196_CR30","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1007\/s00198-017-3909-3","volume":"28","author":"G Ballane","year":"2017","unstructured":"Ballane G, Cauley JA, Luckey MM, El-Hajj Fuleihan G (2017) Worldwide prevalence and incidence of osteoporotic vertebral fractures. Osteoporos Int 28(5):1531\u20131542. https:\/\/doi.org\/10.1007\/s00198-017-3909-3","journal-title":"Osteoporos Int"},{"issue":"7","key":"1196_CR31","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1002\/jbmr.5650110719","volume":"11","author":"TW O\u2019Neill","year":"1996","unstructured":"O\u2019Neill TW et al (1996) The prevalence of vertebral deformity in European men and women: the European vertebral osteoporosis study. J Bone Miner Res 11(7):1010\u20131018. https:\/\/doi.org\/10.1002\/jbmr.5650110719","journal-title":"J Bone Miner Res"},{"issue":"5","key":"1196_CR32","doi-asserted-by":"publisher","first-page":"739","DOI":"10.20945\/2359-3997000000563","volume":"66","author":"L Bandeira","year":"2022","unstructured":"Bandeira L, Silva BC, Bilezikian JP (2022) Male osteoporosis. Arch Endocrinol Metab 66(5):739\u2013746. https:\/\/doi.org\/10.20945\/2359-3997000000563","journal-title":"Arch Endocrinol Metab"},{"issue":"1","key":"1196_CR33","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1177\/1759720X15621227","volume":"8","author":"PM Cawthon","year":"2016","unstructured":"Cawthon PM, Shahnazari M, Orwoll ES, Lane NE (2016) Osteoporosis in men: findings from the Osteoporotic Fractures in Men Study (MrOS). Ther Adv Musculoskelet Dis 8(1):15\u201327. https:\/\/doi.org\/10.1177\/1759720X15621227","journal-title":"Ther Adv Musculoskelet Dis"},{"issue":"3","key":"1196_CR34","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.spinee.2018.08.004","volume":"19","author":"DW Barton","year":"2019","unstructured":"Barton DW, Behrend CJ, Carmouche JJ (2019) Rates of osteoporosis screening and treatment following vertebral fracture. Spine J 19(3):411\u2013417. https:\/\/doi.org\/10.1016\/j.spinee.2018.08.004","journal-title":"Spine J"},{"issue":"6","key":"1196_CR35","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1007\/s00223-019-00611-3","volume":"105","author":"M Behanova","year":"2019","unstructured":"Behanova M, Reichardt B, Stamm TA, Zwerina J, Klaushofer K, Kocijan R (2019) Treatment effects of bisphosphonates and denosumab on survival and refracture from real-world data of hip-fractured patients. Calcif Tissue Int 105(6):630\u2013641. https:\/\/doi.org\/10.1007\/s00223-019-00611-3","journal-title":"Calcif Tissue Int"},{"issue":"5","key":"1196_CR36","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1007\/s00198-021-06264-z","volume":"33","author":"H Iida","year":"2022","unstructured":"Iida H et al (2022) Bisphosphonate treatment is associated with decreased mortality rates in patients after osteoporotic vertebral fracture. Osteoporos Int 33(5):1147\u20131154. https:\/\/doi.org\/10.1007\/s00198-021-06264-z","journal-title":"Osteoporos Int"},{"issue":"11","key":"1196_CR37","doi-asserted-by":"publisher","first-page":"2001","DOI":"10.1002\/jbmr.3816","volume":"34","author":"D Bliuc","year":"2019","unstructured":"Bliuc D et al (2019) Reduced bone loss is associated with reduced mortality risk in subjects exposed to nitrogen bisphosphonates: a mediation analysis. J Bone Miner Res 34(11):2001\u20132011. https:\/\/doi.org\/10.1002\/jbmr.3816","journal-title":"J Bone Miner Res"},{"issue":"2","key":"1196_CR38","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1007\/s12020-018-1824-9","volume":"64","author":"L Degli Esposti","year":"2019","unstructured":"Degli Esposti L et al (2019) Use of antiosteoporotic drugs and calcium\/vitamin D in patients with fragility fractures: impact on re-fracture and mortality risk. Endocrine 64(2):367\u2013377. https:\/\/doi.org\/10.1007\/s12020-018-1824-9","journal-title":"Endocrine"},{"issue":"2","key":"1196_CR39","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1007\/s00198-020-05557-z","volume":"32","author":"E McCloskey","year":"2021","unstructured":"McCloskey E et al (2021) The osteoporosis treatment gap in patients at risk of fracture in European primary care: a multi-country cross-sectional observational study. Osteoporos Int 32(2):251\u2013259. https:\/\/doi.org\/10.1007\/s00198-020-05557-z","journal-title":"Osteoporos Int"},{"issue":"7","key":"1196_CR40","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1007\/s00198-020-05377-1","volume":"31","author":"MK Javaid","year":"2020","unstructured":"Javaid MK et al (2020) A patient-level key performance indicator set to measure the effectiveness of fracture liaison services and guide quality improvement: a position paper of the IOF Capture the Fracture Working Group, National Osteoporosis Foundation and Fragility Fracture Network. Osteoporos Int 31(7):1193\u20131204. https:\/\/doi.org\/10.1007\/s00198-020-05377-1","journal-title":"Osteoporos Int"},{"key":"1196_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2023.105574","author":"J Paccou","year":"2023","unstructured":"Paccou J, Philippoteaux C, Cortet B, Fardellone P (2023) Effectiveness of fracture liaison services in osteoporosis. Jt Bone Spine. https:\/\/doi.org\/10.1016\/j.jbspin.2023.105574","journal-title":"Jt Bone Spine"},{"issue":"5","key":"1196_CR42","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1007\/s00198-017-4370-z","volume":"29","author":"CH Wu","year":"2018","unstructured":"Wu CH et al (2018) Identifying characteristics of an effective fracture liaison service: systematic literature review. Osteoporos Int 29(5):1023\u20131047. https:\/\/doi.org\/10.1007\/s00198-017-4370-z","journal-title":"Osteoporos Int"},{"issue":"11","key":"1196_CR43","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1007\/s00402-019-03177-9","volume":"139","author":"J Urrutia","year":"2019","unstructured":"Urrutia J, Besa P, Piza C (2019) Incidental identification of vertebral compression fractures in patients over 60 years old using computed tomography scans showing the entire thoraco-lumbar spine. Arch Orthop Trauma Surg 139(11):1497\u20131503. https:\/\/doi.org\/10.1007\/s00402-019-03177-9","journal-title":"Arch Orthop Trauma Surg"},{"key":"1196_CR44","doi-asserted-by":"publisher","DOI":"10.1186\/s12880-022-00811-8","author":"D Na","year":"2022","unstructured":"Na D et al (2022) Underdiagnosis and underreporting of vertebral fractures on chest radiographs in men aged over 50 years or postmenopausal women with and without type 2 diabetes mellitus: a retrospective cohort study. BMC Med Imaging. https:\/\/doi.org\/10.1186\/s12880-022-00811-8","journal-title":"BMC Med Imaging"},{"issue":"5","key":"1196_CR45","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1007\/s00198-020-05710-8","volume":"32","author":"T Ong","year":"2020","unstructured":"Ong T et al (2020) Integration of a vertebral fracture identification service into a fracture liaison service: a quality improvement project. Osteoporos Int 32(5):921\u2013926. https:\/\/doi.org\/10.1007\/s00198-020-05710-8","journal-title":"Osteoporos Int"}],"container-title":["Calcified Tissue International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00223-024-01196-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00223-024-01196-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00223-024-01196-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T12:12:10Z","timestamp":1714479130000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00223-024-01196-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,26]]},"references-count":45,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,5]]}},"alternative-id":["1196"],"URL":"https:\/\/doi.org\/10.1007\/s00223-024-01196-2","relation":{},"ISSN":["1432-0827"],"issn-type":[{"value":"1432-0827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,26]]},"assertion":[{"value":"22 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Mette Friberg Hitz has received grants from Amgen and UCB Nordic. Speaker honorarium\u00a0from UCB and Amgen and participation in Advisory Boards with UCB and Novo Nordic. Magnus Gr\u00f8nlund\u00a0Bendtsen has received speaker honorarium from UCB Nordic, Gedeon Richter Nordic, and Novo Nordisk.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Informed consent from the patients was not obtained, as the study was approved as a quality assurance\/development study with retrospective collection of data and no intervention by the local data committee (REG-145-2021) and the the hospital\u2019s board of directors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and Animal Rights"}}]}}