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Claire Hill has served in an advisory capacity for Mereo BioPharma and Ultragenyx. Concept and literature search was performed by Claire Hill. All authors contributed to the manuscript, revised the paper critically for intellectual content and have approved the final draft. All authors agree to be accountable for the work and to ensure that any questions relating to the accuracy and integrity of the paper are investigated and properly resolved.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}