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However, there are no available studies that have determined the frequency of osteoporosis in affected patients using gold standard dual-energy X-ray absorptiometry (DXA). In this retrospective comparative study, we analyzed the DXA results of 40 patients with periprosthetic\u00a0femoral hip fractures who were\u00a0treated surgically\u00a0in our department. DXA measurements were performed at the total hip and the lumbar spine to determine bone mineral density T-scores. Data were compared to two age-, sex-, and BMI-matched control groups in which patients underwent DXA prior to aseptic revision\u00a0surgery for other causes or primary THA (consisting of 40 patients each). The mean T-score in the periprosthetic fracture cohort was significantly lower (\u2212\u00a01.78\u2009\u00b1\u20091.78) than that of the aseptic revision (\u2212\u00a00.65\u2009\u00b1\u20091.58, mean difference \u2212\u00a01.13 [95% CI \u2212\u00a01.88 to \u2212\u00a00.37]; <jats:italic>p<\/jats:italic>\u2009=\u20090.001) and the primary THA cohort (\u2212\u00a00.77\u2009\u00b1\u20091.34, mean difference \u2212\u00a01.01 [95% CI \u2212\u00a01.77 to \u2212\u00a00.26]; <jats:italic>p<\/jats:italic>\u2009=\u20090.005). Accordingly, osteoporosis was detected more frequently (45%) in the fracture cohort compared to patients undergoing aseptic revision (12.5%) and primary THA (10%). In conclusion, almost half of the patients with periprosthetic femoral hip\u00a0fractures have osteoporosis according to DXA measurements. A regular assessment of bone health in THA enables identification of patients with osteoporosis who likely benefit from initiation of osteoporosis medication and cemented stem fixation.<\/jats:p>","DOI":"10.1007\/s00223-024-01237-w","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T07:05:31Z","timestamp":1717484731000},"page":"142-149","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Patients with Periprosthetic Femoral Hip Fractures are Commonly Classified as Having Osteoporosis Based on DXA Measurements"],"prefix":"10.1007","volume":"115","author":[{"given":"Jacob","family":"Ritter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assil-Ramin","family":"Alimy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Simon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Hubert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Ries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1058-1307","authenticated-orcid":false,"given":"Tim","family":"Rolvien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank Timo","family":"Beil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,4]]},"reference":[{"key":"1237_CR1","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1097\/00003086-200403000-00012","volume":"420","author":"BA Masri","year":"2004","unstructured":"Masri BA, Meek RM, Duncan CP (2004) Periprosthetic fractures evaluation and treatment. 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