{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T13:23:47Z","timestamp":1766755427376,"version":"3.48.0"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,8,31]],"date-time":"2025-08-31T00:00:00Z","timestamp":1756598400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,8,31]],"date-time":"2025-08-31T00:00:00Z","timestamp":1756598400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Calcif Tissue Int"],"DOI":"10.1007\/s00223-025-01427-0","type":"journal-article","created":{"date-parts":[[2025,8,31]],"date-time":"2025-08-31T07:37:24Z","timestamp":1756625844000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bone Density, Microarchitecture, and Geometry Assessment in Patients with Pachydermoperiostosis Using Second-Generation High-Resolution Peripheral Quantitative Computed Tomography: A Case\u2013Control Study"],"prefix":"10.1007","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5110-334X","authenticated-orcid":false,"given":"Durairaj","family":"Arjunan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1980-430X","authenticated-orcid":false,"given":"Jayaditya","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3541-6474","authenticated-orcid":false,"given":"Sayka","family":"Barry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md. Sadam","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3251-3762","authenticated-orcid":false,"given":"Ashutosh","family":"Rai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rimesh","family":"Pal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0410-8778","authenticated-orcid":false,"given":"Sanjay K.","family":"Bhadada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4101-9432","authenticated-orcid":false,"given":"M\u00e1rta","family":"Korbonits","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5415-1611","authenticated-orcid":false,"given":"Pinaki","family":"Dutta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,8,31]]},"reference":[{"issue":"2","key":"1427_CR1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.220120","volume":"43","author":"H Allen","year":"2023","unstructured":"Allen H, Barnthouse NC, Chan BY (2023) Periosteal pathologic conditions: imaging findings and pathophysiology. Radiographics 43(2):e220120","journal-title":"Radiographics"},{"issue":"1","key":"1427_CR2","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-018-1961-z","volume":"13","author":"A Joshi","year":"2019","unstructured":"Joshi A, Nepal G, Shing YK, Panthi HP, Baral S (2019) Pachydermoperiostosis (Touraine-Solente-Gole syndrome): a case report. J Med Case Rep 13(1):39","journal-title":"J Med Case Rep"},{"issue":"3","key":"1427_CR3","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1590\/S0365-05962011000300027","volume":"86","author":"MB Guerini","year":"2011","unstructured":"Guerini MB, Barbato MT, S\u00e1 NB, Nunes DH, Zeni PR (2011) Pachydermoperiostosis: the complete form of the syndrome. An Bras Dermatol 86(3):582\u2013584","journal-title":"An Bras Dermatol"},{"issue":"3","key":"1427_CR4","doi-asserted-by":"publisher","first-page":"280","DOI":"10.5114\/ceji.2022.120171","volume":"47","author":"J W\u00f3jtowicz","year":"2022","unstructured":"W\u00f3jtowicz J, Ko\u0142odziejczyk B, Gazda A, Gietka P (2022) Primary hypertrophic osteoarthropathy\u2014a rare cause of pain and arthritis in children. Description of 5 cases. Cent Eur J Immunol 47(3):280\u2013287","journal-title":"Cent Eur J Immunol"},{"issue":"8","key":"1427_CR5","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.1002\/jbmr.3157","volume":"32","author":"SS Li","year":"2017","unstructured":"Li SS, He JW, Fu WZ, Liu YJ, Hu YQ, Zhang ZL (2017) Clinical, biochemical, and genetic features of 41 Han Chinese families with primary hypertrophic osteoarthropathy, and their therapeutic response to etoricoxib: results from a six-month prospective clinical intervention. J Bone Miner Res 32(8):1659\u20131666","journal-title":"J Bone Miner Res"},{"issue":"8","key":"1427_CR6","doi-asserted-by":"publisher","first-page":"1453","DOI":"10.1007\/s00198-023-06784-w","volume":"34","author":"Q Pang","year":"2023","unstructured":"Pang Q, Xu Y, Liao R, Li Y, Zhang L, Chi Y, Qi X, Li M, Jiang Y, Wang O, Xing X, Qin L, Xia W (2023) Comparison of bone microstructure and strength in the distal radius and tibia between the different types of primary hypertrophic osteoarthropathy: an HR-pQCT study. Osteoporos Int 34(8):1453\u20131464","journal-title":"Osteoporos Int"},{"issue":"1","key":"1427_CR7","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/s00198-019-05168-3","volume":"31","author":"Q Pang","year":"2020","unstructured":"Pang Q, Xu Y, Qi X, Huang L, Hung VW, Xu J, Liao R, Hou Y, Jiang Y, Yu W, Wang O, Li M, Xing X, Xia W, Qin L (2020) Impaired bone microarchitecture in distal interphalangeal joints in patients with primary hypertrophic osteoarthropathy assessed by high-resolution peripheral quantitative computed tomography. Osteoporos Int 31(1):153\u2013164","journal-title":"Osteoporos Int"},{"key":"1427_CR8","doi-asserted-by":"crossref","unstructured":"Stelmachowska-Bana\u015b M, Barry S, Angurala I, Rice T, Magid K, Carreira A, Rai A, Evans A, Bollington M, Kaur V, Singhmar S, Silaghi CA, Mandisodza K, McGregor A, Sahoo J, Gupta R, Behera KK, Roy A, Carr I, Loughrey PB, Dutta P, Korbonits M (2025) Endocrine alterations in patients with pachydermoperiostosis. J Clin Endocrinol Metab","DOI":"10.1210\/clinem\/dgaf050"},{"issue":"3","key":"1427_CR9","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1002\/jbmr.4488","volume":"37","author":"Q Pang","year":"2022","unstructured":"Pang Q, Xu Y, Huang L, Li Y, Lin Y, Hou Y, Hung VW, Qi X, Ni X, Li M, Jiang Y, Wang O, Xing X, Qin L, Xia W (2022) Bone geometry, density, microstructure, and biomechanical properties in the distal tibia in patients with primary hypertrophic osteoarthropathy assessed by second-generation high-resolution peripheral quantitative computed tomography. J Bone Miner Res 37(3):484\u2013493","journal-title":"J Bone Miner Res"},{"issue":"1","key":"1427_CR10","doi-asserted-by":"publisher","first-page":"99","DOI":"10.5604\/15093492.1032795","volume":"15","author":"M Waszczykowski","year":"2013","unstructured":"Waszczykowski M, Fabi\u015b J, Zwierzchowski TJ, Waszczykowska E (2013) Evaluation of effectiveness of osteoporosis treatment in patient with pachydermoperiostosis according to densitometric findings. Case study. Ortop Traumatol Rehabil 15(1):99\u2013105","journal-title":"Ortop Traumatol Rehabil"},{"issue":"1","key":"1427_CR11","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1007\/s11684-013-0246-6","volume":"7","author":"Z Zhang","year":"2013","unstructured":"Zhang Z, Zhang C, Zhang Z (2013) Primary hypertrophic osteoarthropathy: an update. Front Med 7(1):60\u201364","journal-title":"Front Med"},{"issue":"1","key":"1427_CR12","doi-asserted-by":"publisher","first-page":"23480","DOI":"10.1038\/srep23480","volume":"6","author":"AI Birkhold","year":"2016","unstructured":"Birkhold AI, Razi H, Duda GN, Weinkamer R, Checa S, Willie BM (2016) The periosteal bone surface is less mechano-responsive than the endocortical. Sci Rep 6(1):23480","journal-title":"Sci Rep"},{"key":"1427_CR13","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1235040","volume":"14","author":"Q Lu","year":"2023","unstructured":"Lu Q, Xu Y, Zhang Z, Li S, Zhang Z (2023) Primary hypertrophic osteoarthropathy: genetics, clinical features and management. Front Endocrinol (Lausanne) 14:1235040","journal-title":"Front Endocrinol (Lausanne)"}],"container-title":["Calcified Tissue International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00223-025-01427-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00223-025-01427-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00223-025-01427-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T13:21:03Z","timestamp":1766755263000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00223-025-01427-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,31]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["1427"],"URL":"https:\/\/doi.org\/10.1007\/s00223-025-01427-0","relation":{},"ISSN":["1432-0827"],"issn-type":[{"type":"electronic","value":"1432-0827"}],"subject":[],"published":{"date-parts":[[2025,8,31]]},"assertion":[{"value":"29 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Durairaj Arjunan, Jayaditya Ghosh, Sayka Barry, Md. Sadam Hussain, Ashutosh Rai, Rimesh Pal, Sanjay K. Bhadada, M\u00e1rta Korbonits, and Pinaki Dutta declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Obtained.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Patient Consent"}},{"value":"None.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Presentation at a Meeting"}},{"value":"All participants provided written informed consent before undergoing any evaluations or procedures. The study received approval from the Institute Ethics Committee (IEC: INT\/IEC\/2021\/SPL-24) and was conducted in alignment with the Declaration of Helsinki.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and Animal Rights and Informed Consent"}}],"article-number":"116"}}