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Previous studies suggest that brief, high-impact exercise during short-term energy restriction may stimulate an osteogenic response and mitigate the negative effect of LEA on bone health. This randomized, crossover study of twelve recreational female runners (age: 26.4\u2009\u00b1\u20093.9\u00a0years, VO\n                    <jats:sub>2max<\/jats:sub>\n                    : 45.3\u2009\u00b1\u20097.2\u00a0mL\/kg\/min) assessed the short-term effects of jumping exercises on markers of bone formation and resorption after five days of experimentally-controlled LEA (15\u00a0kcal\/kgFFM\/d). Participants completed two LEA conditions that involved daily treadmill running with either no additional exercise (RUN) or an additional 50 jump exercises per day (RUN\u2009+\u2009J). Fasted bone markers and hormone concentrations were measured on the mornings immediately before and after each intervention period. Bone resorption marker \u03b2-CTX was increased over time in both LEA conditions (main effect of time:\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.005; preRUN: 0.32\u2009\u00b1\u20090.21, postRUN: 0.36\u2009\u00b1\u20090.15\u00a0ng\/mL; preRUN\u2009+\u2009J: 0.38\u2009\u00b1\u20090.21, postRUN\u2009+\u2009J: 0.42\u2009\u00b1\u20090.19\u00a0ng\/mL) with no interaction effect (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.716). Bone formation biomarkers, PINP and sclerostin, did not change over time (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.517,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.091) or between conditions (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.187,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.666). In conclusion, performing 50 jumping exercises during short-term LEA did not have an effect on markers of bone resorption or formation during short-term LEA induced by running exercise and dietary energy restriction.\n                  <\/jats:p>","DOI":"10.1007\/s00223-026-01564-0","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T13:43:09Z","timestamp":1782394989000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of High-Impact Exercise on Bone Marker Concentrations During Controlled Low Energy Availability in Recreational Female Runners"],"prefix":"10.1007","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7959-9412","authenticated-orcid":false,"given":"Trisha","family":"Sterringer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5816-4169","authenticated-orcid":false,"given":"Craig","family":"Sale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Morozov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiarui","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9695-5474","authenticated-orcid":false,"given":"D. 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