{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:45:43Z","timestamp":1791225943332,"version":"4.1.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,7,27]],"date-time":"2011-07-27T00:00:00Z","timestamp":1311724800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Pharmacol"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1007\/s00228-011-1101-9","type":"journal-article","created":{"date-parts":[[2011,7,26]],"date-time":"2011-07-26T06:08:42Z","timestamp":1311660522000},"page":"101-105","source":"Crossref","is-referenced-by-count":9,"title":["Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect?"],"prefix":"10.1007","volume":"68","author":[{"name":"The French Pharmacovigilance Centres Network and The Toxidermia Group of the French Society of Dermatology","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e9lie","family":"Daveluy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Milpied","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annick","family":"Barbaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9n\u00e9dicte","family":"Lebrun-Vignes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurore","family":"Gouraud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Laure","family":"Laroche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ecaterina","family":"Ciobanu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"B\u00e9gaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghada","family":"Miremont-Salam\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Haramburu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,7,27]]},"reference":[{"key":"1101_CR1","unstructured":"Assurance maladie (2009) M\u00e9dicaments rembours\u00e9s par le R\u00e9gime g\u00e9n\u00e9ral au cours des ann\u00e9es 2004 \u00e0 2008. http:\/\/www.ameli.fr\/fileadmin\/user_upload\/documents\/MedicAM_2004-2008_ameli.zip . Accessed 18 January 2011"},{"key":"1101_CR2","unstructured":"Minist\u00e8re de la sant\u00e9: Commission nationale de pharmacovigilance (1987) Enqu\u00eate sur les h\u00e9patites \u00e0 la fluindione"},{"key":"1101_CR3","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1111\/j.1365-2125.1991.tb03922.x","volume":"32","author":"P Tubert","year":"1991","unstructured":"Tubert P, B\u00e9gaud B, Haramburu F, P\u00e9r\u00e9 JC (1991) Spontaneous reporting: how many cases are required to trigger a warning? Br J Clin Pharmacol 32:407\u2013408","journal-title":"Br J Clin Pharmacol"},{"key":"1101_CR4","first-page":"782","volume":"14","author":"M Biour","year":"1990","unstructured":"Biour M, Davy JM, Poynard T, L\u00e9vy VG (1990) La fluindione est-elle h\u00e9patotoxique? Gastroenterol Clin Biol 14:782","journal-title":"Gastroenterol Clin Biol"},{"key":"1101_CR5","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.gcb.2008.07.003","volume":"32","author":"JF Cadranel","year":"2008","unstructured":"Cadranel JF, Demontis R, Seddik M, Ramdani S, Belloula D, Biour M (2008) Toxicit\u00e9 h\u00e9patique et r\u00e9nale de la fluindione (Previscan\u00ae). Gastroenterol Clin Biol 32:816\u2013818","journal-title":"Gastroenterol Clin Biol"},{"key":"1101_CR6","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/0248-8663(96)80823-X","volume":"16","author":"F Grunenberger","year":"1995","unstructured":"Grunenberger F, Thiry L, Sader N, Schlienger JL, Imler M (1995) Fi\u00e8vre prolong\u00e9e induite par la fluindione. Rev Med Interne 16:973\u2013974","journal-title":"Rev Med Interne"},{"key":"1101_CR7","first-page":"390","volume":"46","author":"B Gilson","year":"1991","unstructured":"Gilson B, Aymard JP, Trechot P, Bindi P, Netter P, Gay G (1991) Thrombocytop\u00e9nie et n\u00e9phropathie tubulo-interstitielle associ\u00e9es \u00e0 la prise de fluindione. Therapie 46:390\u2013391","journal-title":"Therapie"},{"key":"1101_CR8","doi-asserted-by":"crossref","first-page":"455","DOI":"10.5414\/CNP66455","volume":"66","author":"S Belmouaz","year":"2006","unstructured":"Belmouaz S, Desport E, Abou Ayache R, Thierry A, Mignot A, Bauwens M, Goujon JM, Bridoux F, Touchard G (2006) Acute immuno-allergic interstitial nephritis caused by fluindione. Clin Nephrol 66:455\u2013458","journal-title":"Clin Nephrol"},{"key":"1101_CR9","first-page":"1014","volume":"128","author":"A Sparsa","year":"2001","unstructured":"Sparsa A, B\u00e9dane C, Benazahary H, De Vencay P, Gauthier ML, Le Brun V, Boulinguez S, Loustaud-Ratti V, Soria P, Vidal E, Bonnetblanc JM (2001) Syndrome d\u2019hypersensibilit\u00e9 m\u00e9dicamenteuse \u00e0 la fluindione. Ann Dermatol Venereol 128:1014\u20131018","journal-title":"Ann Dermatol Venereol"},{"key":"1101_CR10","doi-asserted-by":"crossref","first-page":"445","DOI":"10.2165\/00002018-200225060-00009","volume":"25","author":"EG Brown","year":"2002","unstructured":"Brown EG (2002) Effects of coding dictionary on signal generation: a consideration of use of MedDRA compared with WHO-ART. Drug Saf 25:445\u2013452","journal-title":"Drug Saf"},{"key":"1101_CR11","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1111\/j.1365-2133.2006.07704.x","volume":"156","author":"SH Kardaun","year":"2007","unstructured":"Kardaun SH, Sidoroff A, Valeyrie-Allanore L, Halevy S, Davidovici BB, Mockenhaupt M, Roujeau JC (2007) Variability in the clinical pattern of cutaneous side effects of drugs with systemic symptoms: does a DRESS syndrome really exist? Br J Dermatol 156:609\u2013611","journal-title":"Br J Dermatol"},{"key":"1101_CR12","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.amjmed.2011.01.017","volume":"124","author":"P Cacoub","year":"2011","unstructured":"Cacoub P, Musette P, Descamps V, Meyer O, Speirs C, Finzi L, Roujeau JC (2011) The DRESS syndrome: a literature review. Am J Med 124:588\u2013597","journal-title":"Am J Med"},{"key":"1101_CR13","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.annder.2010.01.005","volume":"137","author":"A Perrin-Lamarre","year":"2010","unstructured":"Perrin-Lamarre A, Petitpain N, Trechot P, Cuny J, Schmutz J, Barbaud A (2010) Toxidermies aux glycopeptides: r\u00e9sultats des explorations immunoallergologiques dans une s\u00e9rie de huit cas. Ann Dermatol Venereol 137:101\u2013105","journal-title":"Ann Dermatol Venereol"},{"key":"1101_CR14","first-page":"111","volume":"40","author":"B B\u00e9gaud","year":"1985","unstructured":"B\u00e9gaud B, Evreux JC, Jouglard J, Lagier G (1985) Imputation of the unexpected or toxic effects of drugs. Actualization of the method used in France. Therapie 40:111\u2013118","journal-title":"Therapie"},{"key":"1101_CR15","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.tox.2004.12.022","volume":"210","author":"JC Roujeau","year":"2005","unstructured":"Roujeau JC (2005) Clinical heterogeneity of drug hypersensitivity. Toxicology 210:123\u2013133","journal-title":"Toxicology"},{"key":"1101_CR16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2332\/allergolint.55.1","volume":"55","author":"T Shiohara","year":"2006","unstructured":"Shiohara T, Inaoka M, Kano Y (2006) Drug-induced hypersensitivity syndrome (DIHS): a reaction induced by a complex interplay among herpes viruses and antiviral and antidrug immune responses. Allergol Int 55:1\u20138","journal-title":"Allergol Int"},{"key":"1101_CR17","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1111\/j.1365-2133.2007.07775.x","volume":"156","author":"T Shiohara","year":"2007","unstructured":"Shiohara T, Iijima M, Ikezawa Z, Hashimoto K (2007) The diagnosis of a DRESS syndrome has been sufficiently established on the basis of typical clinical features and viral reactivation. Br J Dermatol 156:1045\u20131092","journal-title":"Br J Dermatol"},{"key":"1101_CR18","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S1085-5629(96)80038-1","volume":"15","author":"H Bocquet","year":"1996","unstructured":"Bocquet H, Bagot M, Roujeau JC (1996) Drug-induced pseudolymphoma and drug hypersensitivity syndrome (drug rash with eosinophilia and systemic symptoms: DRESS). Semin Cutan Med Surg 15:250\u2013257","journal-title":"Semin Cutan Med Surg"},{"key":"1101_CR19","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/S0151-9638(05)79566-1","volume":"132","author":"E Frouin","year":"2005","unstructured":"Frouin E, Roth B, Grange A, Grange F, Tortel MC, Guillaume JC (2005) Syndrome d'hypersensibilit\u00e9 \u00e0 la fluindione (Previscan\u00ae). Positivit\u00e9 des tests \u00e9picutan\u00e9s. Ann Dermatol Venereol 132:1000\u20131002","journal-title":"Ann Dermatol Venereol"},{"key":"1101_CR20","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1001\/jama.1997.03550220101014","volume":"278","author":"RD deShazo","year":"1997","unstructured":"deShazo RD, Kemp SF (1997) Allergic reactions to drugs and biologic agents. JAMA 278:1895\u20131906","journal-title":"JAMA"},{"key":"1101_CR21","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1136\/pgmj.46.537.452","volume":"46","author":"JS Wright","year":"1970","unstructured":"Wright JS (1970) Phenindione sensitivity with leukaemoid reaction and hepato-renal damage. Postgrad Med J 46:452\u2013455","journal-title":"Postgrad Med J"},{"key":"1101_CR22","volume-title":"Martindale. The complete drug reference","author":"SC Sweetman","year":"2009","unstructured":"Sweetman SC (2009) Martindale. The complete drug reference, 36th edn. Pharmaceutical Press, London","edition":"36"},{"key":"1101_CR23","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s00228-011-1005-8","volume":"67","author":"N Pereira de Silva","year":"2011","unstructured":"Pereira de Silva N, Piquioni P, Kochen S, Saidon P (2011) Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic anti-epileptic drugs. Eur J Clin Pharmacol 67:463\u2013470","journal-title":"Eur J Clin Pharmacol"},{"key":"1101_CR24","doi-asserted-by":"crossref","first-page":"385","DOI":"10.2165\/00002018-200629050-00003","volume":"29","author":"L Hazell","year":"2006","unstructured":"Hazell L, Shakir SAW (2006) Under-reporting of adverse drug reactions: a systematic review. Drug Saf 29:385\u2013396","journal-title":"Drug Saf"},{"key":"1101_CR25","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1046\/j.1365-2125.1997.05417.x","volume":"43","author":"Y Moride","year":"1997","unstructured":"Moride Y, Haramburu F, Requejo AA, B\u00e9gaud B (1997) Under-reporting of adverse drug reactions in general practice. Br J Clin Pharmacol 43:177\u2013181","journal-title":"Br J Clin Pharmacol"}],"container-title":["European Journal of Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00228-011-1101-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00228-011-1101-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00228-011-1101-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T12:48:53Z","timestamp":1558702133000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00228-011-1101-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,27]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["1101"],"URL":"https:\/\/doi.org\/10.1007\/s00228-011-1101-9","relation":{},"ISSN":["0031-6970","1432-1041"],"issn-type":[{"value":"0031-6970","type":"print"},{"value":"1432-1041","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7,27]]}}}