{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T05:10:25Z","timestamp":1792300225502,"version":"4.4.0"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Pharmacol"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1007\/s00228-012-1215-8","type":"journal-article","created":{"date-parts":[[2012,1,31]],"date-time":"2012-01-31T08:01:40Z","timestamp":1327996900000},"page":"1043-1047","source":"Crossref","is-referenced-by-count":6,"title":["Differences in lercanidipine systemic exposure when administered according to labelling: in fasting state and 15 minutes before food intake"],"prefix":"10.1007","volume":"68","author":[{"given":"Covadonga","family":"\u00c1lvarez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estrella","family":"G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Sim\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Govantes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Guerra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Fr\u00edas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Garc\u00eda-Arieta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,2,1]]},"reference":[{"issue":"22","key":"1215_CR1","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.2165\/00003495-200363220-00013","volume":"63","author":"LM Bang","year":"2003","unstructured":"Bang LM, Chapman TM, Goa KL (2003) Lercanidipine: a review of its efficacy in the management of hypertension. Drugs 63(22):2449\u20132472","journal-title":"Drugs"},{"issue":"3","key":"1215_CR2","first-page":"173","volume":"1","author":"C Borghi","year":"2005","unstructured":"Borghi C (2005) Lercanidipine in hypertension. Vasc Health Risk Manag 1(3):173\u2013182","journal-title":"Vasc Health Risk Manag"},{"issue":"8","key":"1215_CR3","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1517\/17425250903085135","volume":"5","author":"M Burnier","year":"2009","unstructured":"Burnier M, Pruijm M, Wuerzner G (2009) Treatment of essential hypertension with calcium channel blockers: what is the place of lercanidipine? Exp Opin Drug Metab Toxicol 5(8):981\u2013987","journal-title":"Exp Opin Drug Metab Toxicol"},{"issue":"3","key":"1215_CR4","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1345\/aph.1H299","volume":"41","author":"C Beckey","year":"2007","unstructured":"Beckey C, Lundy A, Lutfi N (2007) Lercanidipine in the treatment of hypertension. Ann Pharmacother 41(3):465\u2013473","journal-title":"Ann Pharmacother"},{"issue":"1\u20132","key":"1215_CR5","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jchromb.2004.09.038","volume":"813","author":"VA Jabor","year":"2004","unstructured":"Jabor VA, Coelho EB, Lanchote VL (2004) Enantioselective pharmacokinetics of lercanidipine in healthy volunteers. J Chromatogr B Analyt Technol Biomed Life Sci 813(1\u20132):343\u2013346","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"issue":"Suppl 2","key":"1215_CR6","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1097\/00005344-199729002-00002","volume":"29","author":"M Barchielli","year":"1997","unstructured":"Barchielli M, Dolfini E, Farina P, Leoni B, Targa G, Vinaccia V, Tajana A (1997) Clinical pharmacokinetics of lercanidipine. J Cardiovasc Pharmacol 29[Suppl 2]:S1\u2013S15","journal-title":"J Cardiovasc Pharmacol"},{"key":"1215_CR7","unstructured":"Medicine and Healthcare products Regulatory Agency (2006) Summary of Products Characteristics of Zanidip 10\u00a0mg tablets. Available at: http:\/\/www.medicines.org.uk\/emc\/medicine\/17624\/SPC . Accessed 1 May 2011"},{"key":"1215_CR8","unstructured":"Medicine and Healthcare products Regulatory Agency (2010) Public Assessment Report of Zanidip Novum 8\u00a0mg and 16\u00a0mg film coated tablets. 2 February 2010. Available at: http:\/\/www.mhra.gov.uk\/home\/groups\/par\/documents\/websiteresources\/con099740.pdf . Accessed 1 May 2011"},{"key":"1215_CR9","unstructured":"Medsafe, New Zealand Medicines and Medical Devices Safety Authority (2002). Zanidip Data Sheet. 23 January 2002. Available at: http:\/\/www.medsafe.govt.nz\/profs\/datasheet\/z\/Zanidiptab.htm . Accessed 1 May 2011"},{"key":"1215_CR10","unstructured":"Therapeutic Goods Administration (2010) Lercanidipine Sandoz Product Information. 30 September 2010. Available at: http:\/\/www.medicines.org.au\/files\/smplercs.pdf . Accessed 1 May 2011"},{"key":"1215_CR11","unstructured":"Medicine and Healthcare products Regulatory Agency (2009) Public assessment report of lercanidipine hydrochloride 10\u00a0mg and 20\u00a0mg film coated tablets. 22 December 2009. Available at: http:\/\/www.mhra.gov.uk\/home\/groups\/par\/documents\/websiteresources\/con120461.pdf . Accessed 1 May 2011"},{"issue":"1","key":"1215_CR12","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.ejpb.2008.02.022","volume":"70","author":"K Higaki","year":"2008","unstructured":"Higaki K, Choe SY, Lobenberg R, Welage LS, Amidon GL (2008) Mechanistic understanding of time-dependent oral absorption based on gastric motor activity in humans. Eur J Pharm Biopharm 70(1):313\u2013325","journal-title":"Eur J Pharm Biopharm"},{"key":"1215_CR13","unstructured":"Society of Hospital Pharmacists of Hong Kong Administration (2009) Zanidip misprints dosage instraction. Posted 24 November 2009. Available at: https:\/\/sites.google.com\/a\/shphk.org.hk\/main\/pharmacists\/medsafe . Accessed 1 May 2011"}],"container-title":["European Journal of Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00228-012-1215-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00228-012-1215-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00228-012-1215-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T12:48:56Z","timestamp":1558702136000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00228-012-1215-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,1]]},"references-count":13,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["1215"],"URL":"https:\/\/doi.org\/10.1007\/s00228-012-1215-8","relation":{},"ISSN":["0031-6970","1432-1041"],"issn-type":[{"value":"0031-6970","type":"print"},{"value":"1432-1041","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,2,1]]}}}